SciFinder® Mobile: Innovation for today's chemical researchers
SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006...
-
date post
23-Jan-2016 -
Category
Documents
-
view
230 -
download
0
Transcript of SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006...
![Page 1: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/1.jpg)
SciFinder®: Part of the process™2006 Edition
Preview
![Page 2: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/2.jpg)
SciFinder®: Part of the process™2006 Edition
SciFinder® 2006 provides new, powerful capabilities for scientists
• New structure searching capabilities
• New reaction display capabilities
• New navigation and usability improvements
![Page 3: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/3.jpg)
SciFinder®: Part of the process™2006 Edition
SciFinder 2006 provides outstanding new capabilities for scientists
• New structure searching capabilities
• New reaction display capabilities
• New navigation and usability improvements
![Page 4: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/4.jpg)
SciFinder®: Part of the process™2006 Edition
Several new structure search capabilities are available
• Similarity Searching
• Powerful new query tools
• New and improved structure search options
![Page 5: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/5.jpg)
SciFinder®: Part of the process™2006 Edition
• Similarity search ranks all compounds in the CAS RegistrySM
database via the Tanimoto algorithm
• Compounds with highest scores included in results
• Similarity search is complementary to substructure search
Similarity searching allows scientists to find new types of answers to their structure questions
![Page 6: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/6.jpg)
SciFinder®: Part of the process™2006 Edition
The Tanimoto algorithm utilizes various chemical descriptors
• Atoms and their direct attachments • Atom sequences• Bond sequences• Degree of connectivity • Type of ring fusion• Element counts• Atom counts• Ring counts
![Page 7: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/7.jpg)
SciFinder®: Part of the process™2006 Edition
An example of a Tanimoto score calculation
• QS = Number of query descriptors = 143• FS = Number of file substance descriptors = 169• C = Number of descriptors common to both = 139
Score = 100 * C = 100 * 139 = 80 (QS + FS – C) (143 + 169 – 139)
![Page 8: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/8.jpg)
SciFinder®: Part of the process™2006 Edition
The fewer the differences between query and answer, the higher the score
Query
![Page 9: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/9.jpg)
SciFinder®: Part of the process™2006 Edition
Similarity searching is accessed via Get Substances
![Page 10: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/10.jpg)
SciFinder®: Part of the process™2006 Edition
An analysis is performed based on similarity scores
![Page 11: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/11.jpg)
SciFinder®: Part of the process™2006 Edition
Selected answers are presented in similarity score order
![Page 12: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/12.jpg)
SciFinder®: Part of the process™2006 Edition
Substances with lower scores show increasing variance with the query
![Page 13: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/13.jpg)
SciFinder®: Part of the process™2006 Edition
Substances with lower scores show increasing variance with the query
![Page 14: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/14.jpg)
SciFinder®: Part of the process™2006 Edition
New structure query tools are available in SciFinder 2006
• Draw a variable attachment point
• Draw a repeating group
![Page 15: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/15.jpg)
SciFinder®: Part of the process™2006 Edition
These new tools are available in the structure editor tool palette
New Variable Attachment Position tool
New Repeating group tool
![Page 16: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/16.jpg)
SciFinder®: Part of the process™2006 Edition
New search options allow scientists to control the relevancy of their answer set
Eliminate substances with no literature references
Describe literature roles of resulting substances
Only retrieve commercially available substances
Control the type of substance retrieved by its chemical classification
![Page 17: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/17.jpg)
SciFinder®: Part of the process™2006 Edition
SciFinder 2006 provides outstanding new capabilities for scientists
• New structure searching capabilities
• New reaction capabilities
• New navigation and usability improvements
![Page 18: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/18.jpg)
SciFinder®: Part of the process™2006 Edition
Reaction searching is being enriched with new content and new features
• Enhanced access to RXN linking
• Query highlighting
• Reaction conditions
• Elucidation of interim RXN steps
• Improved search options, including limit by number of steps
![Page 19: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/19.jpg)
SciFinder®: Part of the process™2006 Edition
New Reaction search options allow scientists to control the relevancy of their answer set
![Page 20: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/20.jpg)
SciFinder®: Part of the process™2006 Edition
Reaction conditions show time, temperature and other parameters
![Page 21: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/21.jpg)
SciFinder®: Part of the process™2006 Edition
Intermediate reactions in a multi-step reaction can be conveniently reviewed
Click on any substance to check substance details, commercial availability or other reactions where this compound is the product or starting material
![Page 22: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/22.jpg)
SciFinder®: Part of the process™2006 Edition
Click any substance in the reaction to get additional information, including retro-synthetic pathways
Reactions ►
![Page 23: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/23.jpg)
SciFinder®: Part of the process™2006 Edition
Click any substance in the reaction to get additional information, including retro-synthetic pathways
![Page 24: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/24.jpg)
SciFinder®: Part of the process™2006 Edition
SciFinder 2006 provides outstanding new capabilities for scientists
• New structure searching capabilities
• New reaction display capabilities
• New navigation and usability improvements
![Page 25: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/25.jpg)
SciFinder®: Part of the process™2006 Edition
New navigation and usability improvements make SciFinder a better research tool
• Duplicate detection and removal• Direct to document/Direct to Library• Mouse-wheel enabled!• New user assistance• New navigation windows• Quick reference lookup with Locate by
Bibliographic Information
![Page 26: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/26.jpg)
SciFinder®: Part of the process™2006 Edition
Duplicate detection and removal are useful when searching in both CAplussm and MEDLINE®
Duplicate references are removed with the click of a mouse!
![Page 27: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/27.jpg)
SciFinder®: Part of the process™2006 Edition
Convenient access to source documents is provided by links from every reference, direct to the document or your library!
![Page 28: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/28.jpg)
SciFinder®: Part of the process™2006 Edition
New user assistance options will provide in-context help
Launched via user assistance button
![Page 29: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/29.jpg)
SciFinder®: Part of the process™2006 Edition
New task navigation windows will reduce mouse clicks for scientists
All explore options in one window!
New Locate capability when looking up something specific
![Page 30: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/30.jpg)
SciFinder®: Part of the process™2006 Edition
The Locate feature allows quick access to specific references
Journal references or patents can be obtained
Input as much or as little of what you know about the reference
Journal names, author names, title words and publication date can be combined
![Page 31: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/31.jpg)
SciFinder®: Part of the process™2006 Edition
SciFinder has become an essential part of the research process!
• Convenient access to CAS content – enriched over time with vital content to support
discovery research
• An array of powerful search technologies– supporting a variety of scientists across the
research enterprise
• Enabled with an easy-to-use interface – designed to maximize efficiency for scientists
![Page 32: SciFinder ® : Part of the process™ 2006 Edition. SciFinder ® : Part of the process™ 2006 Edition SciFinder ® 2006 provides new, powerful capabilities.](https://reader035.fdocuments.in/reader035/viewer/2022062305/56649d4b5503460f94a28719/html5/thumbnails/32.jpg)
SciFinder®: Part of the process™2006 Edition