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REPORT

Ozone

in

Periodontitis Treatment

byProf. Dr. med. dent. Hans-Georg Schneider

Berlin !o". #$$%

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Ozone in Periodontitis Treatment

&ithin the conte't of a clinically controlled st(dy) *atients +ith the diagnosis of*eriodontitis) *ro"ided that the *robing de*th of the gingi"al *oc,ets +as more than mm $.# in) +here treated +ith the ozone generator /OzonyTron0 of the com*any

mymed.Testing criterions +ere the *a*illa bleeding inde' 1PB23 and the meas(rement of thes(lc(s fl(id flo+ rate /S44R0. T+o "ariables +ere (sed in the methodology56. 7ariable a**lication time in different series of e'*eriments

6$ #$ %$ 8$ sec ozone a**lication *er *oc,et and "isit +ith the intensityremaining constant at le"el 8 1cf. chart in ill(stration 63

#. 7ariable c(rrent intensity and +ith that "ariable ozone concentration bychoosing different le"els from le"el % to le"el +ith the a**lication timeremaining constant at 8$ sec *er *oc,et and "isit

Ozone a**lication +as carried o(t in t+o "isits in % - 8 day inter"als9 follo+-(*a**ointment +as set % - 8 days after the last ozone a**lication.

&ith e"ery *atient) the *roced(res mentioned (nder 6. or #. +here follo+ed for thetreatment of the right-hand side) the teeth *eriodontitis in the left-hand side of the:a+s ser"ed as reference. Each initial diagnosis corres*onded to the state afterdebridement) # % +ee,s before ozone a**lication.D(ring the clinical test) no other treatments +ere carried o(t.The /Pa0 *robe) an e'changeable to* *art of the hand-*iece) +hich loo,s li,e a bl(nt*robe) +as (sed for the thera*y. This *robe-sha*ed to* *art +as inserted for abo(t% mm $.6# in in the gingi"al *oc,et 1not to the f(nd(s of the *oc,et3 +hile the de"ice+as acti"ated and +as mo"ed to and fro +ith *end(lar mo"ement. ;onstant *end(larmo"ement is essential) since it ens(res that air can get into the *oc,et and th(s a

*art of the atmos*heric o'ygen can *ermanently be transformed into ozone 1cf.ill(stration #3.

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2ll(stration #5 2nterdental *oc,ets seen from abo"e 1schematically3.&ith *end(lar mo"ement of the Pa *robe 1green circle3) the gingi"al *oc,et isconstantly /"entilated0. The incoming o'ygen is (sed for ozone formation. 2t +o(ld be+rong to lea"e the *robe in one *osition.

2ll(strations % < 8 clearly de*ict the findings of the st(dy.

The left-hand side of both ill(strations sho+s the "ariable /time0 in 8 *airs of col(mns)the # *airs of col(mns on the right-hand side sho+ the "ariable /c(rrent intensity =ozone concentration0.4rom a com*arison of both ill(strations it is "isible that (nder testing conditions bothtesting criteria react nearly in the same +ay.This is not s(r*rising) beca(se e"ery *racticing dentist daily obser"es the connectionbet+een inflammation intensity and gingi"al secretion and therefore ,no+s it from hiso+n e'*erience.The constant decrease of the PB2 and the S44R sho+56. Ozone a**lication needs #$ seconds to ha"e *erce*tible effects.

There is a cons*ic(o(s red(ction bet+een the #$thand the %$thsecond. Bothtesting criteria contin(e decreasing to the 8$ second) b(t as m(ch as before.

#. The effecti"eness of ozone de*ends on its concentration. >e"el isincontestably more effecti"e than le"el %.

The clinical state of the teeth *eriodontitis that ser"ed as reference had notim*ro"ed.2n some indi"id(al tests) smears +ere ta,en from *oc,ets +ith *robing de*ths of? @ mm $.%6 $.% in +ith sterile *a*er *oints. Then the sam*les +ere +ashed in*hysiological sodi(m chloride sol(tion.

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The sha,en mi't(re or s(s*ension +as s*read on ;ol(mbia Agar 1Blood Agar3 andinc(bated at % ; @ 4.The n(mber of the n(mero(s gro+ing germ-colonies +as limited by means of a gridand then co(nted. The res(lt is de*icted in ill(stration .;onsidering the fact that ozone is highly effecti"e against bacteria 1according to

literat(re also against f(ngi and "ir(ses3 on the one hand) and re"erts bac, tomolec(lar o'ygen 1neglecting bonds to organic str(ct(res3 on the other hand) ozoneis a *erfect thera*e(tic agent. !either resistance formation of the microflora norallergic reactions ha"e been obser"ed. Than,s to its gaseo(s state) the thera*e(ticagent is able to *enetrate e"en narro+) hardly accessible and branched ca"ities 1bi-and trif(rcations) fist(lae) ser*igino(s *oc,ets and the li,e3 m(ch better than liC(id)gel or *aste s(bstances.

Prof. Dr. H.-G. Schneider) Berlin

>egends

2ll(stration %5 E"ol(tion of the *a*illa bleeding inde' 1PB23 beca(se of ozonetreatment of *eriodontitis

2ll(stration 85 2nfl(ence of the ozone a**lication on the s(lc(s fl(id flo+ rate1S44R3 as a testing criterion of the *oc,et secretion

2ll(stration 5 Germ red(ction in the gingi"al *oc,ets +ith *robing de*ths of? @ mm $.%6 $.% in after single ozone treatments +ithdifferent d(ration of a**lication

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8

*a*illa bleeding inde' before after ozone treatment

all data in arithmetic a"erage +ith n=#

*er a**lication at le"el 8 8$ sec at the le"el indicated abo"e

s(lc(s fl(id flo+ rate before after ozone treatment

all data in mm in arithmetic a"erage +ith n=#

*er a**lication at le"el 8 intensityfor 8$ sec

a"erage n(mber of bacterial colonies +ith more than 6mm $.$%@ in in diameterin each Petri dish

ozone a**lication before ta,ing the smear) in sec

normalS44R