SATHYABAMA UNIVERSITYfiles.sathyabamauniversity.ac.in/syllabus/2010 UG SYLLABUS/BIOME… ·...

SATHYABAMA UNIVERSITY(Established under section 3 of UGC Act, 1956)

Jeppiaar Nagar, Rajiv Gandhi Salai, Chennai - 119.

SYLLABUSBACHELOR OF TECHNOLOGY PROGRAMME

INBIOMEDICAL ENGINEERING (8 SEMESTERS)

REGULATIONS 2010

SATHYABAMA UNIVERSITYREGULATIONS – 2010

Effective from the academic year 2010-2011 and applicable to the students admitted to the Degree of Bachelorof Engineering / Technology. (Eight Semesters)

1. Structure of Programme

1.1 Every Programme will have a curriculum with syllabi consisting of theory and practical such as:

(i) General core courses comprising Mathematics, Basic Sciences, Engineering Sciences.

(ii) Core course of Engineering / Technology.

(iii) Elective course for specialization in related fields.

(iv) Workshop practice, Computer Practice, Engineering Graphics, Laboratory Work, IndustrialTraining, Seminar Presentation, Project Work, Educational Tours, Camps etc.

1.2 Each semester curriculum shall normally have a blend of lecture courses not exceeding 7 andpractical courses not exceeding 4.

1.3 The medium of instruction, examinations and project report will be in English.

2. Duration of the Programme

A student is normally expected to complete the B.E/B.Tech. Programme in 8 semesters but in any case notmore than 12 consecutive semesters from the time of commencement of the course (not more than 10semesters for those who join 3rd semester under Lateral entry system) The Head of the Department shallensure that every teacher imparts instruction as per the number of hours specified in the syllabus and that theteacher teaches the full content of the specified syllabus for the course being taught.

3. Requirements for Completion of a Semester

A candidate who has fulfilled the following conditions shall be deemed to have satisfied the requirement forcompletion of a semester.

3.1 He/She secures not less than 90% of overall attendance in that semester.

3.2 Candidates who do not have the requisite attendance for the semester will not be permitted to writethe University Exams.

4. Examinations

The examinations shall normally be conducted between October and December during the odd semesters andbetween March and May in the even semesters. The maximum marks for each theory and practical course(including the project work and Viva Voce examination in the Eighth Semester) shall be 100 with the followingbreakup.

(i) Theory Courses

Internal Assessment : 20 Marks

University Exams : 80 Marks

(ii) Practical Courses

Internal Assessment : - -

University Exams : 100 Marks

SATHYABAMA UNIVERSITY FACULTY OF BIO ENGINEERING

B.Tech. (BIOMEDICAL) i REGULATIONS 2010

5. Passing requirements

(i) A candidate who secures not less than 50% of total marks prescribed for the course (For all coursesincluding Theory, Practicals and Project work) with a minimum of 35 marks out of 80 in the UniversityTheory Examinations, shall be declared to have passed in the Examination.

(ii) If a candidate fails to secure a Pass in a particular course, it is mandatory that he/she shall reappearfor the examination in that course during the next semester when examination is conducted in thatcourse. However the Internal Assessment marks obtained by the candidate in the first attempt shallbe retained and considered valid for all subsequent attempts.

6. Eligibility for the Award of Degree

A student shall be declared to be eligible for the award of the B.E/B.Tech. degree provided the student hassuccessfully completed the course requirements and has passed all the prescribed examinations in all the 8semesters within the maximum period specified in clause 2.

7. Award of Credits and Grades

All assessments of a course will be done on absolute marks basis. However, for the purpose of reporting theperformance of a candidate, Letter Grades will be awarded as per the range of total marks (out of 100) obtainedby the candidate as given below:

RANGE OF MARKS FOR GRADES

Range of Marks Grade Grade Points (GP)

90-100 A++ 10

80-89 A+ 9

70-79 B++ 8

60-69 B+ 7

50-59 C 6

00-49 F 0

ABSENT W 0

CUMULATIVE GRADE POINT AVERAGE CALCULATION

The CGPA calculation on a 10 scale basis is used to describe the overall performance of a student inall courses from first semester to the last semester. F and W grades will be excluded for calculatingGPA and CGPA.

CGPA = Σi Ci GPi

Σi Ci

where Ci - Credits for the subject

GPi - Grade Point for the subject

Σi - Sum of all subjects successfully cleared during all the semesters

8. Classification of the Degree Awarded

1. A candidate who qualifies for the award of the Degree having passed the examination in all thecourses of all the semesters in his/her first appearance within a maximum period of 8 consecutivesemesters after commencement of study (maximum of 6 semesters for Lateral entry system whojoin the course in the third semester) securing a CGPA not less than 9.0 shall be declared tohave passed the examination in First Class – Exemplary.


B.Tech. (BIOMEDICAL) ii REGULATIONS 2010

2. A candidate who qualifies for the award of the Degree having passed the examination in all thecourses of all the semesters in his/her first appearance within a maximum period of 8 consecutivesemesters after commencement of study (maximum of 6 semesters for Lateral entry system whojoin the course in the third semester) securing a CGPA not less than 7.5 shall be declared tohave passed the examination in First Class with Distinction.

3. A candidate who qualifies for the award of the Degree having passed the examination in all thecourses of all the semesters within a maximum period of 8 consecutive semesters aftercommencement of study (maximum of 6 semesters for Lateral entry system who join the course inthe third semester) securing a CGPA not less than 6.0 shall be declared to have passed theexamination in First Class.

4. All other candidates who qualify for the award of the Degree having passed the examination in allthe courses of all the 8 semesters within a maximum period of 12 consecutive semesters (10consecutive semesters for Lateral Entry system who join the course in the third semester) afterhis/her commencement of study securing a CGPA not less than 5.0 shall be declared to havepassed the examination in Second Class.

5. A candidate who is absent in semester examination in a course/project work after having registeredfor the same, shall be considered to have appeared in that examination for the purpose ofclassification of degree. For all the above mentioned classification of Degree, the break of studyduring the programme, will be counted for the purpose of classification of degree.

6. A candidate can apply for revaluation of his/her semester examination answer paper in a theorycourse, within 1 week from the declaration of results, on payment of a prescribed fee along withprescribed application to the Controller of Examinations through the Head of Department. TheController of Examination will arrange for the revaluation and the result will be intimated to thecandidate concerned through the Head of the Department. Revaluation is not permitted for practicalcourses and for project work.

Final Degree is awarded based on the following:

CGPA ≥ 9.0 - First Class - Exemplary

CGPA ≥ 7.50 < 9.0 - First Class with Distinction

CGPA ≥ 6.00 < 7.50 - First Class

CGPA ≥ 5.00 < 6.00 - Second Class

Minimum CGPA requirements for award of Degree is 5.0 CGPA.

9. Discipline

Every student is required to observe disciplined and decorous behaviour both inside and outside the Universityand not to indulge in any activity which will tend to bring down the prestige of the University. If a studentindulges in malpractice in any of the University theory / practical examination, he/she shall be liable for punitiveaction as prescribed by the University from time to time.

10. Revision of Regulations and Curriculum

The University may revise, amend or change the regulations, scheme of examinations and syllabi from time totime, if found necessary.


B.Tech. (BIOMEDICAL) iii REGULATIONS 2010

B.Tech. – BIOMEDICAL ENGINEERINGREGULATIONS 2010 - CURRICULUM

Sl.No. SUBJECT CODE NAME OF THE SUBJECT L T P C Page No.

SEMESTER I

THEORY

1 SCHX1001 Environmental Science & Engineering 3 0 0 3 1

2 SMTX1003 Statistics 3 1 0 4 2

3 SPHX1001 Physics of Materials 3 0 0 3 3

4 SCYX1001 Engineering Chemistry 3 0 0 3 4

5 SCSX1002 Programming in C 3 0 0 3 5

6 SBTX1001 Cell Biology 3 0 0 3 6

7 SBTX1002 Basic Microbiology 3 0 0 3 7

8 SPHY4001 Physics Lab – I 0 0 2 1 8

9 SCYX4001 Chemistry Lab – I 0 0 2 1 8

10 SCSX4002 Programming in C Lab 0 0 4 2 8

TOTAL CREDITS 26

SEMESTER II

THEORY

1 SHSX1001 English for Science and Technology 3 0 0 3 9

2 SMTX1004 Engineering Mathematics 3 1 0 4 10

3 SPHX1002 Applied Physics 3 0 0 3 11

4 SCYX1004 Applied Bioorganic Chemistry 3 0 0 3 12

5 SBTX1003 Genetics 3 0 0 3 13

6 SMEX1001 Engineering Graphics 3 0 0 3 14

7 SEEX1003 Electrical Engineering 3 0 0 3 15

8 SPHX4002 Physics Lab – II 0 0 2 1 16

9 SCYX4002 Chemistry Lab – II 0 0 2 1 16

10 SBMX4001 Microbiology Lab & Biochemisrty Lab 0 0 4 2 16

TOTAL CREDITS 26

L - Lecture hours; T - Tutorial hours; P - Practical hours; C - Credits


B.Tech. (BIOMEDICAL) iv REGULATIONS 2010


SEMESTER III

THEORY

1 SMTX1009 Engineering Mathematics – III 3 1 0 4 17

2 SBTX1007 Introduction to Immunology 3 0 0 3 18

3 SBMX1001 Bioinstrumentation & Measurements 3 0 0 3 19

4 SECX1001 Electronic Devices 3 0 0 3 20

5 SBMX1002 Human Anatomy & Physiology 3 0 0 3 21

6 SECX1004 Signals & Systems 3 1 0 4 22

7 SBMX1003 Biosensors & Transducers 3 0 0 3 23

8 SBMX4002 Biotransducers Lab 0 0 2 1 24

9 SECX4016 Electronic Devices Lab 0 0 2 1 24

10 SBMX4003 Human Anatomy & Physiology Lab 0 0 4 2 24

TOTAL CREDITS 27

SEMESTER IV

THEORY

1 SECX1014 Electronic Circuit 3 0 0 3 25

2 SCSX1003 Programming in C++ 3 0 0 3 26

3 SBMX1004 Medical Pathology 3 0 0 3 27

4 SECX1002 Digital Systems 3 0 0 3 28

5 SBMX1005 Biofluids & Biomechanics 3 0 0 3 29

6 SBMX1006 Digital Signal Processing & its Application 3 1 0 4 30

7 SCSX4007 Programming Lab in C++ Lab 0 0 2 1 31

8 SECX4045 Digital System Lab 0 0 2 1 31

9 SBMX4004 Immunology & Pathology Lab 0 0 4 2 31

TOTAL CREDITS 23


B.Tech. (BIOMEDICAL) v REGULATIONS 2010


SEMESTER V

THEORY

1 SMTX1013 Discrete Mathematics & Numerical Methods 3 1 0 4 32

2 SBMX1007 Radiology 3 0 0 3 33

3 SBMX1008 Artificial Organs & Prosthesis 3 0 0 3 34

4 SBMX1009 Analytical Instrumentation 3 1 0 4 35

5 SECX1015 Microprocessor & Microcontroller 3 0 0 3 36

6 SECX1030 Biosignal Conditioning 3 1 0 4 37

7 SBAX1001 Principles of Management & Professional Ethics 3 0 0 3 38

8 SBMX4005 Medical Electronics Lab 0 0 4 2 39

9 SECX4010 Microprocessor & Microcontroller Lab 0 0 4 2 39

TOTAL CREDITS 28

SEMESTER VI

THEORY

1 SMEX1017 Resource Management Techniques 3 0 0 3 40

2 SEEX1029 Biological Control System 3 1 0 4 41

3 SECX1067 Medical Image Processing 3 0 0 3 42

4 SBMX1010 Diagnostic Instrumentation 3 0 0 3 43

5 Elective – I 3 0 0 3

6 Elective – III 3 0 0 3

7 SBMX4006 Diagnostic Instrumentation Lab 0 0 4 2 44

8 SECX4040 Medical Image Processing Lab 0 0 2 1 44

9 SECX4041 Digital Signal Processing Lab 0 0 2 1 44

TOTAL CREDITS 23


B.Tech. (BIOMEDICAL) vi REGULATIONS 2010


SEMESTER VII

THEORY

1 SBMX1011 Biomaterials 3 0 0 3 45

2 SECX1068 Biotelemetry 3 0 0 3 46

3 SBMX1012 Rehabilitation Engineering 3 0 0 3 47

4 SBMX1013 Therapeutic Insrumentation 3 0 0 3 48

5 Elective – III 3 0 0 3

6 Elective – IV 3 0 0 3

7 SBMX4007 Therapeutic Instrumentation Lab 0 0 4 2 52

TOTAL CREDITS 21

SEMESTER VIII

THEORY

1 SCSX1055 Fuzzy Logic & Neural Networks 3 0 0 3 49

2 SBMX1027 Virtual BioInstrumentation 3 0 0 3 50

3 SBMX1014 Hospital Management 3 0 0 3 51

4 SBMX4008 Virtual Instrumentation Lab 0 0 4 2 52

5 S24XPROJ Project Work 0 0 30 15 52

TOTAL CREDITS 26

TOTAL CREDITS FOR THE COURSE 200


B.Tech. (BIOMEDICAL) vii REGULATIONS 2010

ELECTIVE LIST

Note: ONE SUBJECT IS TO BE CHOSEN FROM EACH GROUP COMPULSORILY


Group I: Computer Science

1 SBMX1016 Telemedicine 3 0 0 3 53

2 SBMX1017 Computers in Medicine 3 0 0 3 54

3 SCSX1053 Artificial Intelligence and Expert Systems 3 0 0 3 55

4 SCSX1054 Computer Graphics and Volume Visualization 3 0 0 3 56

5 SCSX1007 Java Programming 3 0 0 3 57

Group II: Electronic Science

6 SECX1069 Nano Electronics 3 0 0 3 58

7 SICX1016 Fundamental of Mechatronics 3 0 0 3 59

8 SECX1070 Pic and Embedded Systems 3 0 0 3 60

9 SBMX1015 BioMems & Nanotechnology 3 0 0 3 61

10 SBMX1026 Hardware Description Language (VHDL/Verilog) 3 0 0 3 62

Group III: Life Science

11 SBTX1027 Tissue and Stem cell Engineering 3 0 0 3 63

12 SBTX1028 Genetic Engineering and its Application 3 0 0 3 64

13 SBTX1021 Neuroscience 3 0 0 3 65

14 SBMX1023 Pharmacology and Toxicology 3 0 0 3 66

15 SBMX1024 Forensic Science 3 0 0 3 67

16 SBMX1020 Medical Waste Management 3 0 0 3 68

Group IV: Advance Processing Techniques

17 SBMX1018 Advances in Cardiac Signal Processing 3 0 0 3 69

18 SBMX1019 Electrophysiology 3 0 0 3 70

19 SBMX1022 Biophotonics 3 0 0 3 71

20 SBMX1025 Modelling of Physiological System 3 0 0 3 72

21 SICX1020 Theory of Robotics and Automation 3 0 0 3 73

22 SBMX1021 Research Methodology & Medical Ethics 3 0 0 3 74


B.Tech. (BIOMEDICAL) viii REGULATIONS 2010

DUAL DEGREE IN COMPUTER SCIENCE

Provision for candidates from Non-IT Branches of B.E/B.Tech to undergo Dual Degree Programme leading toB.E in Computer Science.

A. Duration and Curriculum

Candidates selected for a Dual degree programme shall undergo additional courses pertaining to ComputerScience. These courses constitute with additional Curriculum as per annexure and consist of both core courseand electives. The additional courses are to be undergone concurrently from the 3rd semester of the B.E/B.Tech.(Non-IT) degree programme and extends for one more year beyond the fourth year of the regular B.E/B.Tech.(Non-IT) degree programme to which he/she was first admitted. The additional courses are to be offered from3rd to 8th Semester after normal working hours so that the regular B.E/B.Tech. (NonIT) remains unaffected.

B. A candidate undergoing dual degree programme should satisfy minimum attendance requirements for the courseof additional Curriculum for each semester, as stipulated for the regular B.E/B.Tech. Degree Programme.

C. For the courses of additional Curriculum, a candidate has to write the same examination that is held for theregular B.E. Computer Science.

D. The passing rules for the dual degree programme shall be same as that of the regular B.E/B.Tech. Degreeprogramme.

E. A candidate shall be declared to be eligible for the additional degree of B.E. Computer Science provided that

(i) The candidate has qualified for the regular B.E. or B.Tech. Degree in the non-IT branch in whichhe/she was originally admitted.

(ii) The candidate has successfully completed all the courses prescribed in the additional Curriculumwithin a maximum period of 12 semesters from the date of first admission.

(iii) There is no disciplinary action pending against the student.


B.Tech. (BIOMEDICAL) ix REGULATIONS 2010

CURRICULUM

SUBJECTS FOR DUAL DEGREE PROGRAMME IN COMPUTER SCIENCE

THIRD SEMESTER

Sl.No. SUBJECT CODE NAME OF THE SUBJECT L T P C

THEORY

1 SCSX1004 Software Engineering 3 0 0 3

2 SCSX1005 Data Structures & Algorithms 3 1 0 4

PRACTICALS

3 SCSX4004 Data Structures Lab 0 0 4 2

TOTAL CREDITS 9

FOURTH SEMESTER

THEORY

1 SCSX1007 Java Programming 3 0 0 3

2 SCSX1009 Computer Architecture & Organization 3 0 0 3

PRACTICALS

3 SCSX4005 Java Programming Lab 0 0 4 2

TOTAL CREDITS 8

FIFTH SEMESTER

THEORY

1 SCSX1017 Data Communication and ComputerNetworks

3 1 0 4

2 SCSX1018 Database Systems 3 1 0 4

PRACTICALS

3 SCSX4011 RDBMS Lab 0 0 4 2

TOTAL CREDITS 10

SIXTH SEMESTER

THEORY

1 SCSX1019 System Programming 3 0 0 3

2 SCSX1022 J2EE 3 0 0 3

PRACTICALS

3 SCSX4010 System Programming Lab 0 0 4 2

TOTAL CREDITS 8


B.Tech. (BIOMEDICAL) x REGULATIONS 2010

SEVENTH SEMESTER

THEORY

1 SCSX1008 C# and .Net 0 0 0 3

2 SCSX1011 Operating System 3 1 0 4

PRACTICALS

3 SCSX4006 C# and .Net Lab 0 0 4 2

TOTAL CREDITS 9

EIGHTH SEMESTER

THEORY

1 SCSX1024 Network Programming & Management 3 0 0 3

2 Elective I 3 0 0 3

3 Elective II 3 0 0 3

PRACTICALS

4 SCSX4012 Network Programming Lab 0 0 4 2

TOTAL CREDITS 11

NINETH SEMESTER

THEORY

1 SCSX1023 Computer Graphics & MultimediaSystems

3 0 0 3

2 SCSX1030 Datamining & Warehousing 3 0 0 3

3 SCSX1025 Wireless & Mobile Networks 3 0 0 3

4 SCSX1027 Hardware Peripherals and Interfacing 3 0 0 3

5 Elective III 3 0 0 3

6 Elective IV 3 0 0 3

PRACTICALS

7 SCSX4014 Hardware Peripherals Lab 0 0 4 2

8 SCSX4015 Case Tools & Testing Lab 0 0 4 2

TOTAL CREDITS 22

TENTH SEMESTER

1 S11XPROJ Project Work and Viva-Voce 0 0 30 15

TOTAL CREDITS 15

TOTAL COURSE CREDITS : 92


B.Tech. (BIOMEDICAL) xi REGULATIONS 2010

ELECTIVES FOR DUAL DEGREE PROGRAMME IN COMPUTER SCIENCE

Sl.No. SUBJECT CODE NAME OF THE SUBJECT L T P C

1. SCSX1020 Component Based Technology 3 0 0 3

2. SCSX1026 Cryptography & Network Security 3 0 0 3

3. SCSX1028 Distributed Computing 3 0 0 3

4. SCSX1032 Management Information System 3 0 0 3

5. SCSX1036 FOSS 3 0 0 3

6. SCSX1038 Software Quality Assurance and Testing 3 0 0 3

7. SCSX1039 Unified Modeling Language 3 0 0 3

8. SCSX1042 Robotics 3 0 0 3

9. SCSX1043 Unix Internals 3 0 0 3

10. SCSX1044 Multicore Programming 3 0 0 3

11. SCSX1047 High Performance Network 3 0 0 3

12. SCSX1048 Grid Computing 3 0 0 3

13. SCSX1049 Client Server Architecture 3 0 0 3

14. SCSX1050 TCP/IP and Socket Programming 3 0 0 3

15. SCSX1057 Cloud Computing 3 0 0 3


B.Tech. (BIOMEDICAL) xii REGULATIONS 2010

SCHX1001ENVIRONMENTAL SCIENCE AND ENGINEERING

(Common to All Branches of B.E / B.Tech)

L T P Credits Total Marks

3 0 0 3 100

UNIT I INTRODUCTION TO ENVIRONMENTAL STUDIES AND NATURAL RESOURCES 12 hrs.

Definition, scope and importance - need for public awareness - forest resources: use and over-exploitation,deforestation, case studies. Timber extraction, mining, dams, floods, drought, conflicts over water, dams-benefits andproblems - mineral resources: use effects on forests and tribal people - water resources: use and over-utilization ofsurface and ground water - exploitation, environmental effects of extracting and using mineral resources, case studies- food resources: world food problems, changes caused by agriculture and overgrazing, effects of modern agriculture,fertilizer-pesticide problems, water logging, salinity, case studies - energy resources: growing energy needs, renewableand non renewable energy sources, use of alternate energy sources. Case studies - land resources: land as a resource,land degradation, man induced landslides, soil erosion and desertification - role of an individual in conservation ofnatural resources - equitable use of resources for sustainable lifestyles. UNIT II ECOSYSTEMS AND BIODIVERSITY 12 hrs.

Concept of an ecosystem - structure and function of an ecosystem - producers, consumers and decomposers- energy flow in the ecosystem - ecological succession - food chains, food webs and ecological pyramids - introduction,types, characteristic features, structure and function of the (a) forest ecosystem (b) grassland ecosystem (c) desertecosystem (d) aquatic ecosystems (ponds, streams, lakes, rivers, oceans, estuaries) - introduction to biodiversity -definition: genetic, species and ecosystem diversity - biogeographical classification of India - value of biodiversity:consumptive use, productive use, social, ethical, aesthetic and option values - biodiversity at global, national and locallevels - India as a mega-diversity nation - hot-spots of biodiversity - threats to biodiversity: habitat loss, poaching ofwildlife, man-wildlife conflicts - endangered and endemic species of India - conservation of biodiversity: in-situ andex-situ conservation of biodiversity.UNIT III ENVIRONMENTAL POLLUTION 10 hrs.

Definition - causes, effects and control measures of: (a) air pollution (b) water pollution (c) soil pollution (d)marine pollution (e) noise pollution (f) thermal pollution (g) nuclear hazards - solid waste management: causes, effectsand control measures of urban and industrial wastes - role of an individual in prevention of pollution - pollution casestudies - disaster management: floods, earthquake, cyclone and landslides.UNIT IV SOCIAL ISSUES AND THE ENVIRONMENT 8 hrs.

From unsustainable to sustainable development - urban problems related to energy - water conservation, rainwater harvesting, watershed management - resettlement and rehabilitation of people; its problems and concerns, casestudies - environmental ethics: issues and possible solutions - climate change, global warming, acid rain, ozone layerdepletion, nuclear accidents and holocaust, case studies. - wasteland reclamation - consumerism and waste products- environment protection act - air (prevention and control of pollution) act - water (prevention and control of pollution)act - wildlife protection act - forest conservation act - issues involved in enforcement of environmental legislation -public awareness.UNIT V HUMAN POPULATION AND THE ENVIRONMENT 8 hrs.

Population growth, variation among nations - population explosion - family welfare programme - environmentand human health - human rights - value education - HIV / AIDS - women and child welfare - role of informationtechnology in environment and human health - case studies.

Visit to a local area to document environmental assets-river/forest/grassland/hill/mountain. Visit to a local pollutedsite-urban/rural/ industrial/agricultural-study of common plants, insects, birds-study of simple ecosystems-pond, river, hillslopes etc.TEXT / REFERENCE BOOKS:1. Meenakshi.P, Elements of Environmental Science and Engineering, 1st Edition, PHI New Delhi, 2009.2. Ravikrishnan. A, Environmental Science & Engineering, 3rdedition, Sri Krishna Publications, Chennai, 2008.3. Wrigh.R.T & Nebel B.J, Environmental science-towards a sustainable future by Richard 8th Edition, Prentice Hall of India, New Delhi,

2006.4. Erach Bharucha ,Text Book of Environmental Studies, University Press, Chennai, 2006.

UNIVERSITY EXAM QUESTION PAPER PATTERN:Max. Marks: 80 Exam Duration: 3 hrs.

PART A : 2 Questions from each unit, each carrying 2 marks 20 marks

PART B : 2 Questions from each unit with internal choice, each carrying 12 marks 60 marks


B.Tech. (BIOMEDICAL) 1 REGULATIONS 2010

SMTX1003STATISTICS

(Common to BIOGROUPS)


3 1 0 4 100

UNIT I BASIC STATISTICS 10 hrs.

Measures of central tendency: Mean, Median, Mode, Harmonic mean, Geometric mean- Measures of dispersion:Range, Mean deviation, Quartile deviation and Standard deviation- coefficients of variation, Skewness and Kurtosis.

UNIT II CORRELATION AND REGRESSION 10 hrs.

Karl Pearson’s Correlation coefficient, Spearman’s Rank correlation coefficient, Tied ranks- Linear RegressionAnalysis - Multiple and Partial Correlation - Multiple Linear Regression (Three variables) Problems only.

UNIT III INTRODUCTION TO PROBABILITY 10 hrs.

Definitions, sample space, events, Addition Law of probability, Multiplication law- conditional probability- Bayestheorem (without proof)

UNIT IV ONE DIMENSIONAL RANDOM VARIABLES 10 hrs.

Definition of a random variable- Discrete and continuous random variables, Probability Mass function, ProbabilityDensity Function, Cumulative Distribution Function- Mathematical expectation - Mean and Variance applications only.

UNIT V BASIC THEORETICAL DISTRIBUTIONS 10 hrs.

Binomial Distribution, Poisson Distribution and Normal Distribution, Mean and Variance (applications only)

TEXT / REFERENCE BOOKS:

1. Irivin Miller and John E Freund, Probability and Statistics for Engineers, Prentice Hall , 1977. 2. Veerarajan T, Probability, Statistics and Random Process, 4th Edition, Tata McGraw Hill, 2008 3. Murray R. Spiegel, Schaum’s Outline of Theory and Problems of Probability and Statistics, Mcgraw-Hill,1975. 4. Ronald E. Walpole, Raymond H. Myers, Sharon L. Myers, Keying Ye , Probability & Statistics for Engineers & Scientists,

8th Edition, Prentice Hall, 2006 5. Stephen Bernstein, Schaum’s Outline of Elements of Statistics I: Descriptive Statistics and Probability, McGraw-Hill,1998.

UNIVERSITY EXAM QUESTION PAPER PATTERN

Max Marks : 80 Exam Duration : 3 hrs





SPHX1001PHYSICS OF MATERIALS

(Common to all Branches of B.E / B.Tech)


3 0 0 3 100

UNIT I CONDUCTING AND SUPERCONDUCTING MATERIALS 10 hrs.Classical Free electron theory of Metals-Derivation of Electrical and Thermal Conductivity- Deduction of

Wiedemann Franz law-Lorentz number. Introduction to Band theory, Difference between Conductors, Semiconductorsand Insulators - Superconductivity-Transition temperature - occurrence of superconductivity - BCS Theory(Qualitative),properties of superconductors -Type I &Type II superconductors, High Tc superconductors, AC & DC Josephson effects.Applications of superconductors – basic concepts of SQUID, cryotron, magnetic levitation.UNIT II MAGNETIC AND DIELECTRIC MATERIALS 10 hrs.

Types based on spin. Hard and soft magnetic materials, domain theory of Ferromagnetism, magnetic bubbles,formation and propagation of magnetic bubbles, applications of magnetic materials - Magnetic storage devices. Dielectricparameters, polarization, polarisability, types of polarization. Internal or local electric field - derivation of Lorentz Equationand Clausius - Mossotti Equation, dielectric loss and breakdown, types of dielectric breakdown, types of dielectricmaterials, applications.UNIT III OPTICAL MATERIALS 10 hrs.

Optical processes and Excitons - types, Traps - Trapping and recombination, types, Point defects –Frenkel andSchottky defects - Colour centers - types and their mechanisms, Luminescence - Photoluminescence - Types-Fluorescence and Phosphorescence- Mechanism and its applications, Cathodoluminescence, Electroluminescence.Non-linear Optical Materials – Basic Principle, Classifications, Properties - Frequency Doubling or Tripling, Optical Mixing- Applications.UNIT IV MODERN ENGINEERING MATERIALS 10 hrs.

Metals and alloys – steel and its properties - Iron-carbon phase diagram, Titanium and Aluminium based alloys- Introduction, properties and Applications. Shape Memory Alloys (SMA) - Principle of shape memory effects, Hysteresiscurve, Two way shape memory alloys, super-elasticity and thermo-mechanical behavior. Characterization methods toidentify the phase transformation of SMA, commercial SMA – Ni-Ti alloys, copper alloys and Cu-Al alloys, Applications.Ceramics – Classification, Properties, fabrication, advanced ceramics and applications. Composites – particle reinforcedcomposites and fiber reinforced composites – processing and applications.UNIT V CHARACTERIZATION OF MATERIALS 10 hrs.

Structural characterization – X-ray diffraction, electron diffraction and neutron diffraction – Determination of crystalstructure. Difference among these diffraction techniques.Micro structural characterization – optical microscope, scanningelectron microscope, transmission electron microscope, atomic force microscopy, micro and nano hardness testing –principle and applications.REFERENCE BOOKS : 1. Ragavan.V, Material science and Engineerimg, 5th Edition, Eastern Eco, 2004. 2. Suresh.R and Jayakumar.V, Materials Science, 1st Edition, Lakshmi Publication, 2003. 3. Wilson.J and Hawkes.J.F.B, Optoelectronics- An Introduction, 2nd Edition, Prentice-Hall of India, 2001. 4. Dr.Arumugam M., Semiconductor Physics and Opto electronics, 1st Edition, Anuradha Publishers, 2003. 5. Gaur.R.K and Gupta.S.L, Engineering Physics, 8th Edition, Dhanbat Rai Publications,2007. 6. Palanisamy.P.K, Engineering Physics, 1st Edition, SCITECH Publications, 2007. 7. Sankar.B.N and Pillai.S.O, A text book of Engineering Physics, 1st Edition, New Age international Publishers, 2007. 8. Rajendran.V, Engineering Physics, 2nd Edition, Tata McGraw-Hill, 2008. 9. Avadhanulu.M.N and P.G. Kshirsagar.P.G, Engineering Physics, 2nd Edition, S. Chand & Company, 2007.10. Dr. Arumugam M., Engineering Physics, 2nd Edition, Anuradha Publications, 2002.11. William D.Callister,Jr, Materials Science and Engineering An introduction, 6th Edition, John-Wiley and Sons,2004.12. Cullity.B.D, Principles of X-ray diffraction, 3rd Edition, Prentice Hall, 2001

UNIVERSITY EXAM QUESTION PAPER PATTERNMax. Marks: 80 Exam Duration: 3 hrs.PART A : 2 Questions from each unit, each carrying 2 marks 20 marks Out of 20 marks, maximum of 10% problems may be asked. PART B : 2 Questions from each unit with internal choice, each carrying 12 marks 60 marks Out of 60 marks, maximum of 10% problems may be asked ‘Applications’ mentioned in the syllabus refer to the basic applications and not to any specific case.



SCYX1001ENGINEERING CHEMISTRY

(Common to All Branches of B.E / B.Tech)


3 0 0 3 100

UNIT I WATER TECHNOLOGY 10 hrs.Introduction: Impurities present in water, Hardness: Types of hardness, Expression, Units. Estimation of hardness

by EDTA method, Problems. Boiler Troubles: Sludge & Scales, Boiler Corrosion. Water Softening: Zeolite process,Demineralization process, Merits and Demerits. Reverse osmosis, Merits and Demerits. Domestic water treatment: Flowchart diagram only.UNIT II BATTERIES AND FUEL CELLS 10 hrs.

Introduction - Battery terminology: Primary cells, Secondary batteries, Charging and Discharging characteristics,Capacity, Energy density, Cycle life, Internal resistance. Secondary batteries: Lead-acid accumulator, Nickel-cadmiumbatteries , Lithium primary cells: Lithium-thionyl chloride cell, Lithium-iodine cell. Lithium secondary batteries: Lithium-ionbatteries. Fuel cells: Hydrogen-Oxygen fuel cell, Solid oxide fuel cell (SOFC): Principle, construction, anode cathodeand electrolyte. Proton Exchange Membrane Fuel Cell.UNIT III CORROSION SCIENCE 10 hrs.

Introduction - Electrochemical cell representation. Electrochemical series: Significance. Galvanic series.Corrosion: Definition of corrosion, Dry corrosion: Mechanism of Dry corrosion, Pilling-Bedworth rule, Wet Corrosion:

Mechanism. Types of corrosion: Galvanic corrosion, Differential aeration corrosion, Pitting corrosion, Microbial Corrosion.Factors influencing corrosion: Nature of the metal, nature of the environment. Corrosion control: Material selection andDesign, Cathodic protection. Corrosion inhibitors: Anodic, cathodic and Vapour phase inhibitors.UNIT IV EXPLOSIVES AND ROCKET PROPELLANTS 10 hrs.

Introduction - Explosives: Requirements, Classification of Explosives: Low explosives, primary explosives andhigh explosives. Assessment of explosives.

Rocket engines: Types of rocket engines. Basic principle, Mass fraction, Specific impulse, Thrust, Effective exhaustvelocity, Specific propellant consumption. Chemical propellants: Requirements, Classification: Liquid fuels, Liquidoxidizers, Solid fuels, Solid oxidizers.UNIT V SURFACE CHEMISTRY 10 hrs.

Introduction. Adsorption: Types, Adsorption of gases on solids, Adsorption of solutes from solution. Adsorptionisotherms: Freundlich adsorption isotherm, Langmuir adsorption isotherm. Industrial adsorbent materials: Role ofadsorbents in catalysis and water softening. Emulsion: Types: water/oil, oil/water. Applications of adsorption: Cottrell’sprecipitator, Coating of rubber on metals, Electrostatic painting.TEXT / REFERENCE BOOKS: 1. Jain P.C. and Monica Jain,Engineering Chemistry, 15th Edition Dhanpat Rai Publishing Co. 2009 2. Dara S.S., Text Book of Engineering Chemistry, S.Chand & Co, 2008 3. Sheik Mideen A., Engineering Chemistry (I & II),13th Edition, Shruthi Publishers, 2010 4. Parameswara Murthy C, Agarwal C V, Andra Naidu, Textbook of Engineering Chemistry, B S Publications, 2006 5. Kuriakose J.C. and Rajaram J., Chemistry in Engineering and Technology",. Vol.1 & 2, 5th reprint, Tata McGraw Hill Publishing

Company (P) Ltd., 2010. 6. Sharma B.K., Engineering Chemistry, 2nd Edition, Krishna Prakasam Media (P) Ltd., 2001 7. Puri Br, Sharma Lr, Madhan S Pathania, Principles of Physical Chemistry, 41st Edition, Vishal Publishing Co., 2004 8. Mars G Fontana, Corrosion Engineering, 3rd Edition, Tata McGraw Hill, 2008 9. David Linden, Thomas B Reddy, Handbook of Batteries, 4th Edition, McGraw-Hill, 201010. George Paul Sutton, Oscar Biblarz, Rocket Propulsion Elements, 8th Edition, John Wiley & Sons, 2010

UNIVERSITY EXAM QUESTION PAPER PATTERN:

Max. Marks: 80 Exam Duration: 3 hrs



One problem for 5 marks may be asked in Unit 1 - Water Technology



SCSX1002PROGRAMMING IN C

(Common to all Branches of B.E / B.Tech.)


3 0 0 3 100

UNIT I INTRODUCTION 10 hrs.Algorithms & flowcharts-Overview of C-Features of C-IDE of C Structure of C program-Compilation & execution

of C program-Identifiers, variables, expression, keywords, data types, constants, scope and life of variables, local andglobal variables. Operators: arithmetic, logical, relational, conditional and bitwise operators- Special operators: size of() & comma (,) operator-Precedence and associativity of operators & Type conversion in expressions.

Basic input/output and library functions: Single character input/output i.e. getch(), getchar(), getche() &putchar()-Formatted input/output: printf() and scanf()-Library Functions: concepts, mathematical and character functions.

UNIT II CONTROL STRUCTURES AND FUNCTIONS 10 hrs.Conditional control-Loop control and Unconditional control structures.

The Need of a function-User defined and library function- Prototype of a function-Calling of a function-Functionargument-Passing arguments to function- Return values-Nesting of function- main()-Command line arguments andrecursion. Storage class specifier – auto, extern, static, & register.

UNIT III ARRAYS, STRINGS, STRUCTURE AND UNION 10 hrs.

Single and multidimensional arrays-Array declaration and initialization of arrays-Array as function arguments.

Declaration-Initialization and string handling functions.

Defining structure-Declaration of structure variable-Accessing structure members-Nested structures-Array ofstructures-Structure assignment-Structure as function argument-Function that returns structure- Union.

UNIT IV POINTERS AND DMA FUNCTIONS 10 hrs.

The ‘&’ and ‘* ’ operators-Pointers expressions-Pointers vs arrays-Pointer to functions-Function returningpointers-Static and dynamic memory allocation in C.

malloc(), calloc(), sizeof(), free() and realloc()-Preprocessor directives.

UNIT V FILE MANAGEMENT AND GRAPHICS 10 hrs.Defining, opening & closing a file, text file and binary file- Functions for file handling: fopen, fclose, gets, puts,fprint,

fscanf, getw, putw, fputs, fgets, fread, fwrite-Random access to files: fseek, ftell, rewind-File name as Command LineArgument.

Graphics in PC-Initialize Graphics Mode-Functions used In Graphics - Drawing a Point on the Screen-Drawinglines, rectangles, ovals, circles, arcs, polygon, filling colors-Using Text in Graphics Display.

REFERENCE BOOKS: 1. Balaguruswami.E, ‘Programming in C’, TMH Publications, 1997 2. Behrouz A. Forouzan & Richard F. Gilberg, “Computer Science A Structured Programming using C”, 3rd Edition, Cengage Learning, 2007. 3. Gottfried , ‘Programming with C’, schaums outline series, TMH publications, 1997 4. Mahapatra , ‘Thinking in C’, 2nd Edition, PHI Publications, 1998 5. Stevens , ‘Graphics Programming in C’, BPB Publication, 2006 6. Subbura.R , ‘Programming in C’, Vikas Publishing, 1st Edition, 2000


Max Marks : 80 Exam Duration : 3 hrs.





SBTX1001 CELL BIOLOGYL T P Credits Total Marks

3 0 0 3 100

UNIT I CELL STRUCTURE AND FUNCTION OF THE ORGANELLES 10 hrs.

Structure and function of Eukaryotic and prokaryotic cells. Structure and function of cell organelles - mitochondria,nucleus, chloroplast ribosomes and golgibodies.

UNIT II MEMBRANES PROTEINS AND CELL DIVISION 10 hrs.

Structure, principles of membrane organization, membrane models, membrane protein types and its functions.Cell division, mitosis and meiosis, cell cycle and cell cycle control.

UNIT III TRANSPORT ACROSS CELL MEMBRANES 10 hrs.

Passive and active transports, permeases, sodium-potassium pumps, Ca2+ ATPase pumps, lysomal and vascularmembrane, ATP dependent proton pumps, co-transport: symport, antiport and transport into prokaryotic cell, endocytosisand exocytosis.

UNIT IV RECEPTORS AND MODELS OF EXTRA CELLULAR SIGNALING & SIGNAL TRANSDUCTION10 hrs.

Cystosolic, nuclear and membrane bound receptors, autocrine. Paracrine and endocrine models of action. Signalsimplification, CAMP, role of IP3, CAMP and G- proteins role in Signal transduction, calcium influx and is role in cellsignaling.

UNIT V CELL CULTURE 10 hrs.

Study of Cell line, types of cell line, generation of cell lines, maintenance of stock cells, characterization andmorphological analysis of cells.

TEXT BOOK:1. Rastogi S.C., Cell Biology, 3rd Edition, 2005.

REFERENCE BOOKS:1. James E. Darnell, Harvey F. Lodish, David Baltimore, Molecular Cell Biology, Scientific American, 1986.2. Kimball, TW - Cell Biology, Addison Wesley Publishers, 1989.


Max Marks: 80 Exam Duration: 3 hrs





SBTX1002 BASIC MICROBIOLOGYL T P Credits Total Marks

3 0 0 3 100

UNIT I INTRODUCTION 10 hrs.

Historical review of the foundation of microbiology. Whittaker’s five- kingdom concept of living organismClassification of microorganism and methods of classifying and identification of microorganism. Microscopy, light andlaser optic systems. Simple, differential and special stains.

UNIT II STRUCTURAL ORGANIZATION 10 hrs.

General structural organization of Bacteria, Virus, Fungi and Actinomycetes and their reproduction. Bacteriophages,multiplication of bacteriophages-lytic and lysogeny cycle.

UNIT III METHODS OF STERILISATION AND DISINFECTION 10 hrs.

Methods of Sterilisation and disinfection- Physical- dry heat, moist heat, UV light, vibration, radiation, filtration,HEPA filter, Chemical-phenol and phenolic compounds, (halogen aliphatic alcohol, formaldehyde, ethylene oxide, heavymetals) anionic and cationic detergents.

UNIT IV MICROBIAL NUTRITION AND ENVIRONMENT 10 hrs.

Growth of microorganisms in different media - growth curve of microbes and different methods of enumerationof multiplying microorganisms.

UNIT V ENVIRONMENTAL APPLICATION OF MICROBIOLOGY 10 hrs.

Ecology, Recycling of biomaterials, production of bio gas, leaching of ores by microorganisms. Application ofbiofertilizers and biopesticides. Pollution control through user consortium of microorganisms.

TEXT / REFERENCE BOOKS:

1. Pelzer. M.J ., Chan E.C.S., Krig, N., Microbiology Tata Megrew hill publishing company Ltd., New Delhi, 1996.2. Prescott., L.M.harley, J.P. & Klein .D.A., Microbiology, Browb publishers, 1990.3. Schelegel., H.G. General microbiology. Cambridge university press. 1993.4. Heywood, V.H., Watson, R.T. Global biodiversity assessment, Cambridge university press. 1998.


Max Marks: 80 Exam. Duration: 3 hrs.





SPHY4001 PHYSICS LAB - IL T P Credits Total Marks

0 0 2 1 50

1. Torsional pendulum- Determination of MI of the disc and rigidity modulus of the wire.

2. Quincke’s method - Determination of magnetic susceptibility of a liquid

3. Semiconductor diode - Determination of width of the forbidden energy gap

4. Ultrasonic interferometer – Determination of Compressibility of liquid

5. Lees disc - Determination of thermal conductivity of a bad conductor.

6. Optical Fiber – Determination of Numerical aperture and attenuation loss.

SCYX4002 CHEMISTRY LAB - IL T P Credits Total Marks

0 0 2 1 50

1. Determination of total, permanent and temporary hardness of a water sample.

2. Estimation of copper in an ore by iodometric titration.

3. Determination of strength of HCl by conductometric titration.

4. Estimation of the amount of ferrous ion by titrating with chromate ion using potentiometer.

5. Verification of the Freundlich isotherm by using acetic acid adsorption on charcoal.

6. Determination of the rate of corrosion of iron metal by hydrogen evolution method.

SCSX4002PROGRAMMING IN C LAB

(Common to all Branches Except CSE/IT)L T P Credits Total Marks

0 0 4 2 100

1. To write a simple menu driven calculator program using switch statement.

2. To write a program to calculate the nCr using functions.

3. To write a program to find the largest and smallest number using arrays.

4. To write a program to generate Fibonacci series.

5. To write a program to find the factorial of a number using recursion.

6. To write a program to print the sum of elements of an array using pointers.

7. To write a program to implement file handling

8. To write a program to perform matrix addition and multiplication.

9. To write a program to check for perfect number.

10. To write a program to implement string manipulation functions without using library functions.

11. To write a program to perform ASCII equivalent keystrokes.

12. To write a program to solve a polynomial equation.



SHSX1001 ENGLISH FOR SCIENCE AND TECHNOLOGYL T P Credits Total Marks

3 0 0 3 100

UNIT I 10 hrs.

Reading comprehension- Skimming and Scanning - Transcoding -Bar diagram, Tables and Pie chart –Discussingtopics of general interest or on current topics and making a presentation in the class - Conjunctions and discoursemarkers- cloze reading- affixes – definitions- tense- voice – jumbled sentences.

UNIT II 10 hrs.

Subject verb agreement - Idioms and phrases, reading passages to answer evaluative, inferential and hypotheticaltype of questions- Listening - Creative thinking and speaking- Formal letters - application for job- resume preparation-inviting dignitaries to department workshops, symposium and university functions - Letter to the editor.

UNIT III 10 hrs.

Reading and summarising reports - Writing a project proposal - Editing - Checking punctuation and grammaticalerrors- Types of Sentences – preparation of Check List- formulating questions and answers - communicating politely.

UNIT IV 10 hrs.

Reported speech- Parts of speech- confusable words - Report on industrial visit - project report - Making effectivePower Point presentations - speaking about the future plans-expressing opinions-reading and guessing meanings ofunknown words from the context – using appropriate verb forms

UNIT V 10 hrs.

Modal auxiliaries – Presentation of problems and solutions – wh- questions- question tags- punctuation- hyponymy-listening and taking notes – study skills – preparing notes

TEXT / REFERENCE BOOKS:1. Aeda Abidi & Ritu Chowdary, “English For Engineers Made Easy”, Cengage India Learning Limited, New Delhi. 20102. Geetha Nagaraj, “A Course In Grammar and Composition”, Foundation Books Pvt. Ltd., New Delhi, 2006.3. Hewings. M, “Advanced English Grammar”, Cambridge University Press, Chennai. 2000.4. Nagini, P S et al, “Excellence Through communication”, Shri Jai Publications, Chennai, 2005.5. Raman M & Sangeetha Sharma, “Technical Communication”, Oxford University Press, USA 2005.6. Reddy Devika and Chowdhary S, “Technical English”, Mac Millan, Chennai. 20097. Rizvi, M.A., “Effective Technical Communication”, Tata McGRaw Hill Publishing Company Limited, New Delhi, 2006.8. Verma. Shivendra K, “Interactive Grammar of Modern English”, Frank Brothers & Company, India, 2000.



Part A: 10 questions of 2 marks each – no choice 20 marks

Part B: 6 questions from the five units with internal choice, each carrying 10 marks 60 marks



SMTX1004ENGINEERING MATHEMATICS

(Common to Bio-Groups)


3 1 0 4 100

UNIT I MATRICES 10 hrs.

Characteristic equation of a matrix - Eigen values and Eigen vectors of a real matrix- Properties of Eigen valuesand Eigen vectors, Cayley-Hamilton theorem (without proof) verification - Finding Inverse and Power of a matrix usingit - Orthogonal transformation - Reduction of quadratic form to canonical form by Orthogonal transformation.

UNIT II DIFFERENTIAL CALCULUS 10 hrs.

Definitions - Derivative of standard functions (Results only) - Addition, subtraction, Multiplication and Quotientrules of differentiation - Differentiation of function of function - Logarithmic derivatives - Derivatives of implicit function.

UNIT III INTEGRAL CALCULUS 10 hrs.

Integral of standard functions (Results only) -Integration by the method of substitution- Integral of functions of

the type lx + m

ax2 + bx + c ,

lx + m

√ax2 + bx + c,

a sin x + b cos x

c sin x + d cos x. Integration using partial fractions - Integration by parts -

Generalization of integration by parts (Bernoulli’s formula) - Definite integral - Properties - Simple problems.

UNIT IV VECTOR CALCULUS AND BETA, GAMMA FUNCTIONS 10 hrs.

Differentiation of a vector function - Gradient, Divergence and Curl - Directional Derivative - Identities (withoutproof) - Irrotational and Solenoidal fields - Definitions of Beta and Gamma integrals - Relation between them - Properties- Evaluation of definite integrals in terms of Beta and Gamma function - (without the applications to double andtriple integral)

UNIT V PERMUTATION AND COMBINATION 10 hrs.

Fundamental principle of counting - Permutation - Circular permutation - Combination - Relation betweenpermutation and combination (Simple problems). Binomial Theorem (Positive Integral Index only) - General term -

Term independent of x - Coefficient of xn.

TEXT / REFERENCE BOOKS

1. Vittal P R, Allied Mathematics, Margham Publications, 3rd Edition, 2002 2. Venkataraman M.K., Engineering Mathematics - First Year, 2nd Edition, National Publishing Co., Chennai, 2000. 3. Frank Ayres and NBSP Elliot Mendelson, Schaum’s Outline of Theory and Problems of Differential and Integral Calculus, Tata

Mcgraw Hill, 1990. 4. Narayanan S., Manicavachagom Pillay T.K., Ramanaiah G., Advanced Mathematics for Engineering students, Volume I, 2nd Edition,

S.Viswanathan Printers and Publishers, 1992. 5. Kreyszig.E, Advanced Engineering Mathematics, 8th Edition, John Wiley & Sons, Singapore, 2001.







SPHX1002APPLIED PHYSICS

(Common For All Branches)


3 0 0 3 100

UNIT I FIBER OPTICS 10 hrs.

Introduction - Principle and structure of optical fibers-Acceptance angle-Numerical aperture-Types of opticalfibers-Preparation of fiber – Double crucible technique-Types of rays-Theory of propagation of light-Energy loss inoptical fiber- Attenuation and distortion-Fiber splicing – Fusion and mechanical splicing-Fiber connectors -Butt joint andexpanded beam connectors-Optical fiber communication system (block diagram) - Advantages and its applications.UNIT II ACOUSTICS OF BUILDINGS 10 hrs.

Introduction – Musical sound & noise-Characteristics of musical sound : pitch, loudness, quality – Weber-Fechnerlaw-Relation between pitch & frequency-Factors on which intensity & loudness depend-Decibel scale-Sound intensitylevel and sound pressure level-Sound absorption-OWU-Sound absorption coefficient and its measurements –Reverberation - Reverberation time – Standard Reverberation time – Sabine’s formula to determine the Reverberationtime (Jaegar method)- Factors affecting the acoustics of a building and the remedies-Principles to be followed in theacoustical design of a good auditorium.UNIT III FUNDAMENTALS OF DIGITAL ELECTRONICS 10 hrs.

Number systems - Binary, decimal, Hexadecimal and Octadecimal-Conversion from one number system toanother-Binary addition-Subtraction - Subtraction by 1’s & 2’s complement- BCD-ASCII-Excess 3 code and gray code.UNIT IV NANO DEVICES 10 hrs.

Definition-Fabrication-Top down approach and bottom up approach-Nanomagnets – Particulate Nanomagnets,Geometrical Nanomagnets-Magneto Resistance – Ordinary Magneto Resistance, Giant Magneto Resistance, TunnelingMagneto Resistance- Probing Nanomagnetic Materials-Nanomagnetism in Technology-Nano Devices – Injection Laser– Quantum Cascade Laser – Optical Memories and Coulomb Blockade DevicesUNIT V MEDICAL PHYSICS 10 hrs.

Ultrasonics –Introduction- Production of ultrasonic waves - Piezo-electric method-properties-Doppler effect - Bloodflow meter – Determination of upward and downward transit time- A- scan, B-scan and M-scan-X-rays –Introduction-Units of X-rays- Diagnostic technologies of X-rays – Radiography-Fluoroscopy-Image intensifier-Nuclearmedicine – Introduction-units of radioactivity, m

99Tc generator, nuclear medicine imaging devices - Gamma camera.

REFERENCE BOOKS : 1. Mathur.D.S, Heat and Thermodynamics, 5th Edition, Sultan Chand & Sons, 2004. 2. Gerd Keiser, Optical fiber communication, 3rd Edition, Tata Mc Graw Hill, 2000. 3. John M. Senior, Optical fiber communications - Principle and Practice, 2nd Edition, Pearson Education, 2006. 4. Franz J.H, Jain V.K, Optical communication – Components and Systems,1st Edition, Narosa Publications, 2001. 5. Malvino,Leach & Gautam Saha, Digital Principles and applications, 6th Edition, McGraw Hill, 2006. 6. William H. Gothman, Digital electronics – An int. to theory and practice, 2nd Edition, PHL of India, 2007. 7. Roy, Medical Bio Physics, 1st Edition, Saras Publications, 2001. 8. Vasantha Pattabhi, Bio Physics, 1st Edition, Narosa, 2004. 9. Gaur. R.K. and Gupta. S.L., Engineering Physics, 8th Edition, Dhanbat Rai Publications, 2007.10. Avadhanulu. M.N. and. Kshirsagar. P.G, Engineering Physics, 2nd Edition, S. Chand & Company, 2007.11. Dr. Arumugam M., Engineering Physics, 2nd Edition, Anuradha Publications, 2002.12. William D.Callister, Jr, Materials Science and Engineering An introduction, 6th Edition, John-Wiley and Sons, 2004.

UNIVERSITY EXAM QUESTION PAPER PATTERNMax. Marks: 80 Exam Duration: 3 hrs.


Out of 20 marks, maximum of 10% problems may be asked


Out of 60 marks, maximum of 10% problems may be asked

‘Applications’ mentioned in the syllabus refer to the basic applications and not to any specific case



SCYX1004APPLIED BIO-ORGANIC CHEMISTRY

(Common to BIOGROUPS)


3 0 0 3 100

UNIT I CARBOHYDRATES 10 hrs.

Introduction. Classification: Sugars and NonSugars. Glucose: Physical and chemical properties, epimerization,mutarotation, structural elucidation of glucose:open chain and closed chain structure. Sucrose: physical and chemicalproperties, structural elucidation of sucrose. Structure and biological importance of important polysaccharides: starch,cellulose, chitin, heparin and glycoproteins.

UNIT II AMINOACIDS AND PROTEINS 10 hrs.

Aminoacids: classification :α, β, and γ aminoacids, acidic, basic, neutral aminoacids, essential and non essentialamino acids. Preparation: HVZ reaction, Strecker synthesis, Gabriel Phthalamide synthesis. Physical properties:isoelectric point. Chemical properties: reaction of amino group, carboxyl group and both. Proteins: Classification: basedon shape and solubility. Structure of proteins: primary, secondary, tertiary and quaternary.

UNIT III ANTIBIOTICS 10 hrs.

Introduction, Importance, Classification of antibiotics. Pencillin : Production, isolation, properties, constitution andstructure of penicillin, different types of penicillin. Structure and uses of chloramphenicol, oxytetracyclin, ciprofloxacin.

UNIT IV BIOCHEMICAL TECHNIQUES 10 hrs.

Chromatography: classification, principles, adsorption and partition, paper, thin layer chromatography. Elutionanalysis. Gas chromatography (GC): Block diagram. Detectors: Flame Ionization detector (FID). Liquid chromatography:principles, adsorption and partition. HPLC: Block diagram only. Electrophoresis: High voltage Electrophoresis, GEL,PAGE.

UNIT V BIOMATERIALS 10 hrs.

Introduction: Definition. Metal implant materials: Composition and Properties of Titanium and Titanium basedalloys. Dental metals: Dental amalgam, Gold and Ni - Ti Alloys. Ceramic biomaterials : Resorbable ceramics:Hydroxyapetite, Al - Ca phosphate. Polymer biomaterials: PMMA, hydrogels, silicone rubber, nylon . Biologicalapplications of Gold, Silver nanoparticles and carbon nano tubes.

TEXT / REFERENCE BOOKS:1. Powar C.B. and Chatwal G.R , Biochemistry, 5th Edition, Himalaya Publishing House, 2006.2. Charles P.Poole Jr, and Frank J Owens, Introduction to Nanotechnology, John Wiley and Sons, 2006.3. Gurdeep R Chatwal, Organic Chemistry of Natural Products Vol II , 2nd revised Edition, Himalaya Publishing House, 19864. Skoog, Holler and Nieman, Principles of Instrumental Analysis, 5th Edition, Thomas Inc., 2003.5. Tewari K.S., Vishnoi N.K. and Mehrotra S.N., A Text Book of Organic Chemistry, 2nd Revised Edition, Vikas Publications, 2004.6. Rastogi S.C., Biochemistry, 6th Reprint, Tata McGraw Hill Publishing Limited, 2007.7. Willard Merit Dean Settle, Instrumental Methods of Analysis, 7th Edition, CBS Publishers and Distributors, 2007.8. Leninger, Principle of Biochemistry, 5th Edition, Macmillan Worth Publications, 2008.9. Sujatha V Bhat, biomaterials, 2nd Edition, Narosa Publishing house, 2007.10. Joon Park, R.S. Lakes, Biomaterials Introduction, 3rd Edition, Springer, 2007.


Max. Marks: 80 Exam Duration: 3 hrs.





SBTX1003 GENETICSL T P Credits Total Marks

3 0 0 3 100

UNIT I MENDELIAN PRINCIPLE 10 hrs.Mendel and his experiments and the laws of inheritance, Variation on Mendel’s Theme: Incomplete dominance;

Gene interactions (Epistasis; Duplicate, Complementary, Supplementary and Lethal factors)

UNIT II CHROMOSOMES 10 hrs.Structural organization, Variations in the number and structure of chromosomes: Haploids; Missing or extra

chromosomes (Euploids, Aneuploids); Deletion; Duplication; Aberrations; Translocation and other structuralrearrangements. Chromosomal studies - Karyotyping. The chromosomal theory of inheritance; Clues from inheritanceof sex; linkage and crossing over; gene mapping; Genetic recombination in Prokaryotes and Eukaryotes

UNIT III CHEMICAL BASIS OF HEREDITY 10 hrs.Evidence for DNA (and RNA) as genetic material; Basic equivalence in DNA; The Watson and Crick model of

DNA structure. Different physico-chemical properties of DNA (Tm value, cot values, Renaturation Kinetics, C-valueparadox)

UNIT IV BACTERIAL GENETICS 10 hrs.Genetic transfer of characters; Bacterial conjugation, Transformation - Cellular competence and environmental

conditions required for transformation - linkages; Transduction - general, restricted and abortive transductions; Finestructure study through transduction

UNIT V HUMAN GENETICS 10 hrs.Human Chromosomes, Dosage Compensation, Chromosomal abnormalities - sex chromosomal and autosomal.

Inherited disorders, Genetic counseling, Genetic engineering and gene therapy, inborn errors of metabolism.

TEXT BOOK:1. David Friefelder, Molecular Genetics, Narosa publishing house, India, 2006.

REFERENCE BOOKS:1. Gardne, E.J, Principles of Genetics, 7th Edition John Wiby & Sons ltd, 1991.2. Griffith, Fundamentals of Genetics analysis, 7th Edition, W.H. Freeman & Company, Newyork, 2000.


Max Marks: 80 Exam. Duration: 3 hrs.





SMEX1001ENGINEERING GRAPHICS

(Common to all Branches of B.E / B.Tech)


1 2 0 3 100

UNIT I CONSTRUCTION OF PLANE CURVES 10 hrs.

Introduction - Importance of graphics in engineering applications – Use of drafting instruments – BIS specificationsand conventions – Size, layout and folding of drawing sheets – Lettering and dimensioning- Polygons used inengineering practice– methods of construction of pentagon and hexagon– Construction of ellipse, parabola andhyperbola.UNIT II PROJECTION OF POINTS AND LINES 10 hrs.

General principles of orthographic projection – first angle projection – layout of views – projections of points,straight lines located in the first quadrant – Determination of true lengths of lines and their inclinations to the planesof projection – TracesUNIT III PROJECTION OF SOLIDS AND SECTION OF SOLIDS 10 hrs.

Projection of solids like prism, pyramid, cylinder and cone when the axis is inclined to only one plane of projection– Change of position method only - Sectioning of above mentioned solids in simple vertical positions by cutting planeinclined to one reference plane and perpendicular to the other – True shapes of sectionsUNIT IV DEVELOPMENT OF SURFACES AND FREE HAND SKETCHING 10 hrs.

Need for development of surfaces – Development of lateral surfaces of simple and truncated solids – Prisms,pyramids, cylinders and cones.- Pictorial representation of engineering objects – Representation of three dimensionalobjects in two dimensional media – Need for multiple views – Developing visualization skills through free hand sketchingof three dimensional objects.UNIT V ISOMETRIC PROJECTIONS & PERSPECTIVE PROJECTIONS 10 hrs.

Principles of isometric projection – Isometric scale – Isometric projections of simple solids and combination ofsolids - Prisms, pyramids, cylinders, cones and spheres (excluding isometric projections of truncated solids) - Perspectiveprojections - Simple objects like – cube, prisms, pyramids by Vanishing point method & Visual Ray method (excludingperspective projections of truncated solids)TEXT / REFERENCE BOOKS:1. Natarajan, K.V, “ A Textbook of Engineering Graphics”, Dhanalakshmi Publishers, Chennai, 2006 .2. Venugopal, K. and Prabhu Raja, V., “Engineering Graphics”, New Age International(P) Ltd.,2008.3. Ramachandran. S, Pandian. K, Ramanamurthy. E.V.V. and Devaraj. R “Engineering Graphics”, AirWalk Publications, Chennai, 20094. IS 10711-2001: Technical Products Documentation – Size and Layout of Drawing Sheets5. IS 9609 (Parts 0 & 1 )-2001: Technical Products Documentation – Lettering6. IS 10714(Part 20)-2001 & SP 46 -2003: Lines for Technical Drawings7. IS 11669-1986 & SP 46-2003: Dimensioning of Technical Drawings8. IS 15021(Parts 1 to 4)-2001: Technical Drawings-Projection Methods

UNIVERSITY EXAM QUESTION PAPER PATTERNMax. Marks : 80 Exam Duration : 3 hrs.


PART A: Equal distribution of questions from each unit.


PART B - Split up:

Unit 1: 1 question from construction of hexagon / pentagon / ellipse &

1 question from construction of parabola / hyperbola

Unit 2: 1 question from projection of points & 1 question from projection of lines inclined to both the planes.

Unit 3: 1 question from projection of solids & 1 question from section of solids.

Unit 4: 1 question from development of surfaces & 1 question from orthographic projection.

Unit 5: 1 question from isometric projection & 1 question from perspective projection.



SEEX1003ELECTRICAL ENGINEERING

(Common to CSE, IT & BIO MED)


2 1 0 3 100

UNIT I D.C.CIRCUITS 12 hrs.Electrical quantities-Ohm’s Law-Resistors – Series and parallel combinations -Kirchoff’s laws-Node and Mesh

Analysis-Star delta Transformation.

UNIT II A.C.CIRCUITS 10 hrs.Sinusoidal functions – RMS (effective) and Average values- Phasor representation – J operator – Sinusoidal

excitation applied to purely resistive, inductive and capacitive circuits – RL, RC and RLC series and parallel circuits– Power and power factor.

UNIT III NETWORK THEOREMS (BOTH DC & AC) 10 hrs.Superposition Theorem – Reciprocity Theorem – Thevenin’s Theorem – Norton’s Theorem – Maximum Power

Transfer Theorem.

UNIT IV MAGNETIC CIRCUITS 10 hrs.Definition of MMF, Flux and reluctance – Leakage factor – Reluctances in series and parallel (series and parallel

magnetic circuits) – Electromagnetic induction – Fleming’s rule – Lenz’s law – Faraday’s laws – Statically anddynamically induced EMF – Self and mutual inductance– Analogy of electric and magnetic circuits.

UNIT V INTRODUCTION TO MACHINES 8 hrs.Construction and principle of DC Generator – Emf equation – Types, Principle of DC Motor – Types, Construction

and principle of single phase Transformer, Stepper motor, AC and DC servomotor.

TEXT BOOKS 1. Mittle. B.N, Aravind Mittle, “Basic Electrical Engineering” , Tata McGraw Hill”, 2nd Edition, Reprint 2009. 2 Theraja. L, “Fundamentals of Electrical Engineering and Electronics”, S.Chand & Co., First Multi colour Edition, 2006, (Reprint

2009).

REFERENCE BOOKS :1. Smarajit Ghosh, “Fundamentals of Electrical and Electronics Engineering” , 2nd Edition, PHI Learning Private Ltd, 2010.2. Wadhwa. C.L, “Basic Electrical Engineering” , 4th Edition, New Age International, 2007.3. Sivanagaraju S, G.Kishor & Srinivasa Rao. C, “Electrical Circuit Analysis”, 1st Edition, Cengage Learning, 2010.4. Nitin Saxena, “ Electrical Engineering”, 2nd Edition, Laxmi Publications Pvt Ltd, 2010.


Max. Marks : 80 Exam Duration : 3 hrs.



(Distribution may be 60% Theory & 40 % Numerical)



SPHX4002 PHYSICS LAB - IIL T P Credits Total Marks

0 0 2 1 50

1. Torsional pendulum- Determination of MI of the disc and rigidity modulus of the wire.

2. Quincke’s method - Determination of magnetic susceptibility of a liquid

3. Semiconductor diode - Determination of width of the forbidden energy gap

4. Ultrasonic interferometer – Determination of Compressibility of liquid

5. Lees disc - Determination of thermal conductivity of a bad conductor.

6. Optical Fiber – Determination of Numerical aperture and attenuation loss.

SCYX4002 CHEMISTRY LAB - IIL T P Credits Total Marks

0 0 2 1 50

1. Determination of total, permanent and temporary hardness of a water sample.

2. Estimation of copper in an ore by iodometric titration.

3. Determination of strength of HCl by conductometric titration.

4. Estimation of the amount of ferrous ion by titrating with chromate ion using potentiometer.

5. Verification of the Freundlich isotherm by using acetic acid adsorption on charcoal.

6. Determination of the rate of corrosion of iron metal by hydrogen evolution method.

SBMX4001 MICROBIOLOGY AND BIOCHEMISTRY LABL T P Credits Total Marks

0 0 4 2 100

MICROBIOLOGY LAB1. Study and Handling of Microscope

2. Staining Procedures

(a) Smear preparation (b) Simple staining (c) Grams staining (d) Capsule staining (e) LPCB staining

3. Sterilization procedures and preparation of solid and liquid media

4. Streak plate method

5. Decimal dilution method

6. Spread plate method

7. Pour plate method

8. Biochemical reactions - Catalase and Oxidase test

BIOCHEMISTRY LAB1. Estimation of Protein by Lowry’s Method

2. Estimation of Inorganic Phosphorus by Fiske Subbareo’s Method

3. Preparation of casein from milk

4. Extraction of fructose from honey

5. Preparation of Aspirin from salicylate

6. Amino acid analysis

7. Carbohydrate analysis



SMTX1009ENGINEERING MATHEMATICS III

(Common to all branches except Bioinformatics)


3 1 0 4 100

UNIT I LAPLACE TRANSFORM 10 hrs.

Transforms of simple functions – properties of transforms – Transforms of derivatives and Integrals – Periodicfunctions – Inverse transforms – Convolution theorems – Initial and final value theorems

UNIT II APPLICATIONS OF LAPLACE TRANSFORM 10 hrs.

Application of Laplace Transforms for solving : linear ordinary differential equations – simultaneous differentialequations – integral equations.

UNIT III COMPLEX VARIABLES 10 hrs.

Analytic functions – Cauchy – Riemann equations in Cartesian and Polar form – properties of analytic functions– construction of analytic functions – conformal mapping – standard types – bilinear transformations.

UNIT IV COMPLEX INTEGRATION 10 hrs.

Cauchy’s integral theorem – integral formula – Taylor’s and Laurent’s series (without proof) – Residues – Cauchy’sresidue theorem – Contour integration and the circle and semi circular contours.

UNIT V THEORY OF SAMPLING AND TEST OF HYPOTHESIS 10 hrs.

Test of Hypothesis – Large sample – test of significance – single proportion - difference of proportions – Singlemean - difference of means. Small sample – students ‘t’ test – single mean – difference of means – Fisher’s test –difference of variance, Exact sample – Chi square test – goodness of fit – independence of attributes.

TEXT / REFERENCE BOOKS:1. Kandasamy, P., Thilagavathy, K., and Gunavathy, K., “Engineering Mathematics”, Volumes II & III (4th Revised Edition), S. Chand

& Co., New Delhi, 2001.2. Venkataraman, M.K. “Engineering Mathematics” Volumes III - A & B, 13th Edition National Publishing Company, Chennai, 1998.3. Veerarajan, T., “Engineering Mathematics”, Tata McGraw Hill Publishing Co., NewDelhi, 1999.4. Grewal, B.S., “Higher Engineering Mathematics” (35th Edition), Khanna Publishers, Delhi, 2000.5. Kreyszig, E., “Advanced Engineering Mathematics” (8th Edition), John Wiley and Sons (Asia) Pvt. Ltd., Singapore, 2001.







SBTX1007 INTRODUCTION TO IMMUNOLOGYL T P Credits Total Marks

3 0 0 3 100

UNIT I INTRODUCTION AND OVERVIEW 10 hrs.

History of the immune system, Types of immunity- Innate and acquired, Cells and Organs of the immune system.Antigens and their characterisitics.

UNIT II HUMORAL IMMUNITY 10 hrs.

Development, differentiation and maturation of B cells; Structure and Function of immunoglobulin, Immunoglobulinclasses and subclasses, Molecular biology of immunologlobulin synthesis, Complement pathways. Hybridoma technologyand application of monoclonal antibodies.

UNIT III CELL MEDIATED IMMUNITY 10 hrs.

Development, differentiation and maturation of T cells; Antigen presenting Cells (APC); Phagocytosis; MajorHistocompatibility complex – MHC Class I and II molecules; Antigen processing and presentation; Cytokines; T cellactivation; Immunological unresponsiveness; Immunosuppression.

UNIT IV IMMUNITY TO SELF AND NON – SELF INFECTION 10 hrs.

Hypersensitivity reactions – Type I, II, III and IV; Organ transplantation – Graft rejection, evidence and mechanismsof graft rejection, prevention of graft rejection, immunosuppressive drugs, HLA and disease; Cancer immunology.Autoimmunity

UNIT V IMMUNOLOGICAL TECHNIQUES 10 hrs.

Agglutination and Precipitation reactions, Immunofluorescence, Immunodiffusion, Immunoelectrophoresis, ELISA,RIA.

TEXT / REFERENCE BOOKS:1. Ivan M.Roitt, “Essential Immunology”, 4th Edition, Blackwell Scientific Publications, Oxford, London, 1980.2. Ivan M. Roitt, Jonathan Brostoff and David K.Male Glower, “Immunology”, 1st Edition, Medical Publishers, London, 1958.3. Richard A.Goldsby, Thomas J.Kindt, Barsara A.Osborne, Janis Kuby, “Immunology”, 5th Edition, Freeman & Company,1991.

UNIVERSITY EXAMINATION QUESTION PAPER PATTERN

Max Marks: 80 Examination duration: 3 hrs.





SBMX1001 BIOINSTRUMENTATION AND MEASUREMENTSL T P Credits Total Marks

3 0 0 3 100


Function elements of measuring instrument-performance characteristics of instruments – static, dynamic -dynamic-errors in measurement-types of errors-sources of errors-statistical analysis. Calibration and standards-processof calibration. Bridge Circuits –Wheatstone bridge. Maxwell’s Inductance capacitance bridge, Wein’s bridge.

UNIT II ANALOG INSTRUMENTS 10 hrs.

Construction and working principle- D’arsonval galvanometer, moving coil instruments-permanent magnet movingcoil instrument, dynamometer instrument, moving iron instruments –attraction type, repulsion type, DC Potentiometerohmmeter.

UNIT III DIGITAL INSTRUMENTS 10 hrs.

Comparison between analog and digital instruments –basic building block of a digital instrument- ramp typedigital voltmeter – digital frequency meter - digital phase meter –digital storage oscilloscope.

UNIT IV SIGNAL GENERATION AND ANALYSIS 10 hrs.

Standard signal generator-a.f.sine and square wave generator-function generator–RF generator. Basic WaveAnalyzer –heterodyne wave analyzer–spectrum analyzer-Harmonic distortion analyzer.

UNIT V DISPLAY DEVICES AND RECORDERS 10 hrs.

Digital Display System and Indicators-classification of display devices-CRT-DOT MATRIX display-light crystaldisplay –strip chart recorders, galvanometer type recorders –self balancing type potentiometric recorders-magnetic tape&disk recorders.

TEXT BOOKS:1. A. K. Sawhney “A course in electronic Measurements and Instruments”, Dhanpat Rai sons, 1991 (Unit: I, II & III)2. H.S. Kalsi “Electronic Instrumentation & Measurement” Tata McGraw HILL, 1995 (Unit: IV & V).

REFERENCES BOOKS:1. W.D cooper and A. D. Helfrick, “Electronic Instruments and Measurements Techniques”, Prentice Hall of India-19912. E. O. Doeblin, “Measurement System – Application & Design”, Mc Graw Hill, 1990

UNIVERSITY EXAM QUESTION PAPER PATTEREN






SECX1001ELECTRONIC DEVICES

(Common to EEE, ECE, E&C, E&I, ETCE and BIO-MED)


3 0 0 3 100

UNIT I SEMICONDUCTOR DIODE 10 hrs.Intrinsic and Extrinsic semiconductor - Charge density, Mobility and Conductivity in Semiconductor, Drift and

diffusion current, Continuity equation, Hall effect - PN junction - Energy band diagram of PN junction, Currentcomponents in PN junction, Junction capacitance - Application of diode - Diode switch, Clipper, Clamper and Voltagemultipliers - Zener diode - Zener voltage regulators.

UNIT II BIPOLAR JUNCTION TRANSISTOR 10 hrs.Construction and Operation of NPN and PNP transistor - Current components in a transistor, Eber moll’s Equation

-Characteristics of CE,CB,CC configuration - Base width modulation, Transistor breakdown, Transistor biasing - BiasStabilization and Compensation, Thermal runway problems, Heat sinks, Switching characteristics.

UNIT III FIELD EFFECT TRANSISTOR 10 hrs.JFET- Construction, Operation and Characteristics, Expression for pinch off voltage and drain current - MOSFET

- Enhancement and Depletion mode operation and characteristics, Handling precautions of MOSFET, Gate capacitance- FET as VVR - Comparison of MOSFET and JFET - Comparison of BJT and JFET.

UNIT IV SPECIAL SEMICONDUCTOR DEVICES 10 hrs.SCR- UJT- Diac- Triac - Varactor diode - PIN diode - Tunnel diode - Gunn diode - Principle of photo electronic

devices - Solar cell, Photo diode and Photo transistor - LED, LCD, LASER diode, CCD - Operation, Characteristicsand Applications.

UNIT V PRINCIPLES OF CRT 10 hrs.Force on charged particle in electric field and magnetic field - Motion of charged particle in electric and magnetic

field - Principles of CRT - Deflection and focusing of electron beam in CRT and TV picture tube-Orientation of electricand magnetic field in CRT - Applications of CRO.

TEXT BOOKS:1. Millman and Halkias, Electronic devices and circuits, 2nd Edition, McGraw Hill Publication, 2007.2. G.K.Mithal, Basic Electronic Devices and circuits, 2nd Edition, G.K.Publishers Pvt. Ltd., 1998.

REFERENCE BOOKS:1. David Bell,Fundamentals of Electronic Devices and Circuits, 5th Edition, Oxford University Press 2008.2. Robert L. Boylestad, Electronic Devices and Circuit Theory, 6th Edition, PHI, 1998.3. Ben G Streetman and Sanjay Banerjee, Solid State Electronic Devices, 6th Edition, Pearson Education, 2005.4. Roody and Coolen, Electronic Communications, 4th Edition, Pearson Education, Reprint 2007.


Max Marks : 80 Exam Duration : 3 hrsPART A : 2 Questions from each unit, each carrying 2 marks 20 marksPART B : 2 Questions from each unit with internal choice, each carrying 12 marks 60 marks



SBMX1002 HUMAN ANATOMY AND PHYSIOLOGYL T P Credits Total Marks

3 0 0 3 100

UNIT I CARDIOVASCULAR PHYSIOLOGY 10 hrs.Composition and physiology of blood; blood group and Rh factor; blood coagulation, structure and function of

hemoglobin. Introduction to the anatomy of heart; orgin, conduction and regulation of heart beat; cardiac cycle;Electrocardiogram; blood pressure; capillary pressure; regulation of blood pressure.

UNIT II DIGESTIVE SYSTEM 10 hrs.Overview of organs of digestive system-mouth, stomach, Small intestine, large intestine, liver and accessory

glands. Digestion & absorption of carbohydrates, lipids and proteins.

UNIT III BONES AND MUSCLES 10 hrs.Classification of bones and types of joints. bone tissue, development and growth of bone. Types of muscle:

skeletal, cardiac and smooth muscle structure. Mechanism of muscle contraction. Structure of neuro muscular junction.

UNIT IV RESPIRATORY PHYSIOLOGY 10 hrs.Structure, mechanics and ventilation of the lung, pulmonary circulation, diffusion and gaseous exchange in the

lungs, convection and transport of gases in the blood, regulation of respiration. structure of eye and ear, physiologyof vision and hearing.

UNIT V RENAL PHYSIOLOGY 10 hrs.Micro-architecture of the kidney, physiology of urine formation, role of the kidney in the regulation of water, salt

and acid base balance, renal disorders.

TEXT BOOKS:1. Ross and Wilson “Anatomy and Physiology in Health and Illness”, 9th Edition, Churchill Livingstone, 2004. (Unit: I, IV & V) 2. Gerard. J. Tortora “Principles of Human Anatomy and physiology”, 7th Edition, Harper Collins College Publishers, 1993.

(Unit: II & III)

REFERENCE BOOKS:1. Arthur C. Guyton& John E. Hall, “Text Book of Medical Physiology”, 10th Edition W.B.Saunders Company, London, 2003.2. P. Saraswathi, “Handbook of Anatomy for Nurses” 1st Edition, Jaypee Brothers Medical Publishers (P) Ltd, 2008


Max. Marks: 80 Exam Duration: 3 hrsPART A : 2 Questions from each unit, each carrying 2 marks 20 marksPART B : 2 Questions from each unit with internal choice, each carrying 12 marks 60 marks



SECX1004SIGNALS AND SYSTEMS

(Common to ECE E&C, E&I and Bio-med Branches)L T P Credits Total Marks

3 1 0 4 100

UNIT I CLASSIFICATION OF SIGNALS 10 hrs.

Continuous time signals (CT signals) and Discrete time signals (DT signals) – Step, Ramp, Pulse, Impulse,Exponential – Classification of CT and DT signals – Periodic, aperiodic and Random signals – Real and Complexsignals – Energy and power signals.

UNIT II ANALYSIS OF CONTINOUS TIME SIGNALS 10 hrs.

Continuous time Fourier Transform and Laplace Transform analysis with examples – Basic properties – Parseval’srelation – Convolution in time and frequency domain – Relation between Fourier transform and Laplace transform.

UNIT III LINEAR TIME INVARIANT CONTINUOUS TIME SYSTEMS 10 hrs.

CT systems – Linear Time invariant Systems – Basic properties of continuous time systems – Linearity, Causality,Time invariance, Stability – Frequency response of LTI systems – Analysis and characterization of LTI systems usingLaplace transform – Computation of impulse response and transfer function using Laplace transform – Differentialequation – Impulse response – Convolution integral and Frequency response.

UNIT IV ANALYSIS OF DISCRETE TIME SIGNALS 10 hrs.

Spectrum of D.T signals, Discrete Time Fourier Transform (DTFT), Discrete Fourier Transform (DFT) – Basicprinciples of z-transform – z-transform definition – Region of convergence – Properties of ROC – Properties ofz-transform – Poles and Zeros – Inverse z-transform using Contour integration – Residue Theorem, Power Seriesexpansion and Partial fraction expansion.

UNIT V LINEAR TIME INVARIANT DISCRETE TIME SYSTEMS 10 hrs.

LTI-DT systems – Characterization using difference equation – Properties of convolution and interconnection ofLTI Systems – Causality and Stability of LTI Systems – Impulse response, Convolution Sum and Frequency response– Computation of Impulse response and Transfer function using Z Transform.

TEXT BOOKS:1. Allan V. Oppenheim et al, ‘Signals and Systems’, 2nd Edition., Prentice Hall of India Pvt. Ltd., 1997.2. P.Ramesh Babu et al, ‘Signals and Systems’, 4th Edition, Scitech publishers, 2010.3. Haykin. S and Van Been. B., ‘Signals and Systems’, 2nd Edition, John Wiley & Sons, .2003.

REFERENCE BOOKS:1. Rao.P, Signals and Systems, 1st Edition, Tata McGraw Hill, 2008.2. Lathi, B. P., Linear Systems and Signals, 2nd Edition, Oxford University Press, 20063. Mrinal Mandal, Amir Asif, Continuous and Discrete Time Signals and Systems, 1st Edition, Cambridge University Press, 2007.4. Roberts, M.J., Fundamentals of Signals and Systems, 1st Edition, Tata McGraw Hill, 20075. S. Salivahanan et al., Digital Signal Processing, 2nd Edition, Tata McGraw Hill, 2009.6. H P Hsu, Signals and Systems, 2nd Edition, Tata McGraw Hill, 2008.





(Distribution may be 40% Theory & 60% Numericals)



SBMX1003 BIOSENSORS AND TRANSDUCERSL T P Credits Total Marks

3 0 0 3 100


General measurement system – purpose, structure and elements-Transducers - Definition, Classification.Resistance type- strain gauges, thermometers, potentiometers. Capacitive type, Inductive type- variable reluctance andLVDT. Biomedical Applications.

UNIT II TRANSDUCERS 10 hrs.

Temperature transducers, Piezoelectric transducers, Piezo resistive transducers, Photoelectric transducers,Pressure transducers. Biomedical applications.

UNIT III BIO POTENTIAL ELECTRODES 10 hrs.

Half cell potential (or) Electrode potential, Types of Electrodes – Micro electrodes, Depth and needle electrodes,Surface electrodes, Chemical electrodes. Catheter type electrodes, stimulation electrodes, electrode paste, electrodematerial.

UNIT IV BIOSENSORS 10 hrs.

Introduction, biological elements, immobilization of biological components. micromachined biosensor – cantileverbased chemical sensors - AFM, FAB. Biochip – introduction, gene chip & proteomic technologies in modern biomedicalscience.

UNIT V APPLICATIONS OF BIOSENSORS 10 hrs.

ISFET for glucose and urea, IMFET, Bananatrode, Enzyme electrodes, PPG sensors, MOSFET biosensors, Ionexchange membrane electrodes.

TEXT BOOKS:1. H.S. Kalsi “Electronic Instrumentation & Measurement” Tata McGraw HILL, 1995 (Unit: I, II & III).2. Brain R Eggins, “Biosensors: An Introduction”, John Wiley Publication, 1997 (Unit: IV & V).

REFERENCE BOOKS:1. A. K.Sawhney “A course in Electronic Measurements and Instruments”, Dhapat Rai & sons, 19912. John G Webster, “Medical Instrumentation: Application and design”, John Wiley Publications, 20013. John P Bentley, “Principles of Measurement Systems”, 3rd Edition, Pearson Education Asia, (2000 Indian reprint)4. Geddes and Baker, “Principles of Applied Biomedical Instrumentation”, 3rd Edition, John Wiley Publications, 2008.







SBMX4002 BIOTRANSDUCERS LABL T P Credits Total Marks

0 0 2 1 50

1. Characteristics of Temperature Transducers.

2. Temperature Measurement using Thermistor and its Linearization characteristics.

3. Characteristics of Optical Transducer.

4. Characteristics of LVDT.

5. Characteristics of Hall effect Transducer.

6. Characteristics of Strain Gauge.

7. Characteristics of Potentiometer Transducer.

SECX4016 ELECTRONIC DEVICES LABL T P Credits Total Marks

0 0 2 1 50

1. Characteristics of PN Diode.

2. Characteristics of Zener Diode.

3. Characteristics of UJT.

4. Characteristics of JFET.

5. Characteristics of DIAC.

6. Characteristics of Common Emitter.

7. Characteristics of Common Collector.

8. Characteristics of Common Base.

9. Characteristics of Transistor.

SBMX4003 HUMAN ANATOMY & PHYSIOLOGY LABL T P Credits Total Marks

0 0 4 2 100

1. Collection, Preservation of Blood and Urine samples

2. Skeletal System

3. Recording of Blood Pressure

4. Determination of Bleeding Time

5. Determination of Clotting Time

6. Estimation of Hemoglobin

7. Red Blood Cell Count

8. Total Leucocytes Count

9. Differential Leucocytes Count

10. Study of Various Types of Tissues



SECX1014ELECTRONIC CIRCUITS(Common to EEE, BIOMED)


3 0 0 3 100

UNIT I RECTIFIERS AND POWER SUPPLIES 10 hrs.Half Wave and Full Wave Rectifier-Bridge rectifier-performance measures of rectifiers-filters-Full Wave rectifier

with inductive filter, capacitive filter, LC filter, π section filter, multiple LC Filter-Regulators-Shunt and series voltageregulators-Performance measures of regulators.

UNIT II BIASING CIRCUITS AND ANALYSIS OF SMALL SIGNAL BJT AMPLIFIERS 10 hrs.Biasing circuit of BJT, DC equivalent circuit of BJT,DC and AC Load Lines, Stability factor analysis, Types of

amplifiers-Small Signal Equivalent circuit-Calculation of gain, Input and Output Impedance of various amplifiers usingh-Parameters.

UNIT III MULTISTAGE AMPLIFIERS AND POWER AMPLIFIERS 10 hrs.Introduction-Two stage RC Coupled amplifier-Cascade amplifier-Darlington emitter follower amplifier-Bootstrap

amplifier

Introduction-Class A Power Amplifier-Push Pull Principle-Class B push pull amplifier and complementary symmetryamplifier-Class C amplifier-Distortion in amplifiers-Collector power dissipation-efficiency and figure of meritcalculation-Maximum power dissipation hyperbola.

UNIT IV FEEDBACK AMPLIFIERS AND OSCILLATORS 10 hrs.Introduction-Performance analysis of feedback amplifiers-Voltage and current feedback amplifiers-Barkhausen

Criterion for Oscillation-RC and Wein bridge oscillator, Hartley Oscillator, Colpitts Oscillator-Crystal Oscillator-Stabilizationin Oscillator.

UNIT V TUNED AMPLIFIERS AND MULTIVIBRATORS 10 hrs.Single tuned amplifier-Stagger tuned amplifier-Tuned amplifier instability-Neutralization and Unilateralization.

TEXT BOOKS: 1. Robert L. Boystead and Louis Nashelky, "Electronic Devices and Circuits", 8th Edition, PHI, 2005.

REFERNCE BOOKS 1. Theodore F. Bogart Jr., Jeffrey S. Beasley, Guillermo Rico, "Electronic devices and circuits", PPH, 2004. 2. Millman & Halkias, "Integrated Electronics", McGraw Hill International Edition. 1991 3. David A. Bell, "Electronic Devices and Circuits", PHI, 2004







SCSX1003PROGRAMMING IN C++(Common to all Branches)


3 0 0 3 100

UNIT I INTRODUCTION TO C++ 10 hrs.Object Oriented Programming Paradigms - Comparison of Programming Paradigms – Object Oriented Languages

- Benefits of Object Oriented Programming - Comparison with C - Overview of C++ -Pointers-References and Structures- Functions - Scope and Namespaces - Source Files and Programs.

UNIT II CLASSES AND OBJECTS 10 hrs.Working with classes – Classes and objects – Class specification-Class objects-Accessing class members-Defining

class members-Inline functions-Accessing member functions within class-Data hiding-Class member accessibility-Emptyclasses, constructors-Parameterized constructors-Constructor overloading-Copy constructors-new, delete operators-”this”pointer-friend classes and friend functions-Function overloading-Operator overloading.

UNIT III DERIVED CLASSES 10 hrs.Base class and derived class relationship-Derived class declaration-Forms of inheritance-Inheritance and member

accessibility- Constructors in derived class-Destructors in derived class-Multiple inheritance-Multi level inheritance-Hybridinheritance-Virtual base classes-Member function overriding-Virtual functions.

UNIT IV I/O AND LIBRARY ORGANIZATION 10 hrs.I/O Stream - File I/O - Exception Handling - Templates - STL – Library Organization and Containers – Standard

Containers - Overview of Standard Algorithms-Iterators and Allocators.

UNIT V OBJECT ORIENTED DESIGN 10 hrs.Development Process – Management - Object Identification – Components - Object Oriented Design

Fundamentals – Case Studies.

TEXT BOOKS:1. Balagurusamy, "Object Oriented Programming with C++", 4th Edition, Tata McGraw Hill, 20102. Venu Gopal.K.R, Ravishankar.T, and Raj kumar, "Mastering C++", Tata McGraw Hill, 1999.

REFERENCE BOOKS:1. Bjarne Stroustrup, "The C++ programming language", 3rd Edition, Addision Wesley, 1998.2. John R Hubbard, “Programming with C++”, Shaums Outline Series, 2nd Edition, McGraw Hill, 2000.3. James Martin & James J.Odell, "Object Oriented methods-A foundation", Prentice Hall, 1997.4. Grady Booch, “Object Oriented Analysis and Design with application”, 2nd Edition, Addission Wesley, 1994.







SBMX1004 MEDICAL PATHOLOGYL T P Credits Total Marks

3 0 0 3 100

UNIT I NORMAL CELL STRUCTURE 10 hrs.

Cell Degeneration and regeneration-Inflammations full process, Pathologic Processes that occur in human body,Inflammation. Apoptosis, Degeneration, Enlargement and Atrophy of organs. Hypertrophy Neoplasia. Basic classification,Difference between benign and malignant tumors - Etiology of tumors - Spread of Tumors.

UNIT II FLUID AND HEAMODYNAMIC DEARRANGEMENT 10 hrs.

Edema, Shock, Hemorrhage – Thrombus –Embolism - Disseminated intra vascular Coagulation-Hematologicaldisorders. Bleeding Disorders - Leukemia-lymphoma.

UNIT III INFECTION AND PATHOLOGICAL PROCESSES 10 hrs.

Bacteria, fungi and virus as potential pathogens, mechanism of pathogenecity, mechanism of development ofresistance. Bacterial– Chlamydial, Mycoplasma, Rickettsial disease - Fungal, protozoal - Helminthic disease.

UNIT IV GENETIC DISORDERS AND IMMUNITY 10 hrs.

Autosomal and sex linked disorders- Storage disorders -Types of hypersensitivity reactions - Immune deficiencysyndrome - Primary-HIV- Autoimmune diseases - SCID, SLE, Rheumatoid arthritis

UNIT V DISORDERS 10 hrs.

Genetic basic of disease - three major classes of genetic disease - chromosomal, monogenic, multifactorial.Molecular basis of Diabetes. Respiratory disorder - Cystic Fibrosis. Tuberculosis and Bronchitis. Cancer - genetic andmolecular basis. Neuropsychiatric disorders - Parkinson’s disease, Alzheimer’s disease.

TEXT BOOK:1. Robbins S.L. &Ramzi S.C, “Pathologic Basic of Diseases”, 7th Edition, W.B. Saunders Co. 1999 (Unit I – V)

REFERENCE BOOKS:1. Anatha Narayanan.R & Jayaram Panicker C.R, “Text Book of Microbiology”, 4th Edition, Orient Laongman, 1998. (Unit III)2. Janis Kuby, “Immunology”, 5thEdition, W.H. Freeman and Company, New York, 2003 (Unit IV)







SECX1002DIGITAL SYSTEMS

(Common to ECE, ETCE, EEE, E&I, E&C and Bio-Med)


3 0 0 3 100

UNIT I DIGITAL CONCEPTS, NUMBER SYSTEMS, BOOLEAN SWITCHING ALGEBRA 10 hrs.

Introduction to Number Systems – Positional Number Systems, Number System conversion, Binary codes –Binary arithmetic, Binary logic functions – Switching algebra – Functionally complete operation sets, Reduction ofswitching equations using Boolean algebra, Realization of switching function.

UNIT II DESIGN OF COMBINATIONAL LOGIC 10 hrs.

Minimal two level networks – Minimization of POS and SOP – Design of two level gate networks – Two levelNAND-NAND and NOR-NOR networks – Karnaugh maps – Advantages and Limitations – Quine McClusky’s method.

UNIT III ARITHMETIC AND STANDARD COMBINATIONAL MODULE AND NETWORKS 10 hrs.

Adders – Subtractors – Binary parallel adders, Parallel subtractors, Parallel adder/subtractors, Binary decodersand encoders – Priority encoders – Multiplexers – MUX as universal combinational modules – Demultiplexers – ALUmodule and comparator modules.

UNIT IV SEQUENTIAL CIRCUITS 10 hrs.

Flip flops – SR, JK, D and T flip flops, Master – Slave flip flops, Characteristic and excitation table – Shiftregisters – Counters – Synchronous and Asynchronous counters – Modulus counters, Up/Down counters – Statediagram, State table, State minimization, Implication chart method.

UNIT V LOGIC FAMILIES AND MEMORIES (QUALITATIVE STUDY ONLY) 10 hrs.

Classification and characteristics of logic family – Bipolar logic family – Saturated logic family – RTL, DTL,DCTL, I2L,TTL, HTL – Non saturated family – Schottky TTL, ECL – Unipolar family – MOS, CMOS – Comparisonof logic families – memories – RAM, ROM, PROM, EPROM, EEPROM, SRAM, DRAM, CCD – PAL, PLA – HCT/HCseries IC’s.

TEXT BOOKS:

1. Morris Mano, “Digital design”, 3rd Edition, Prentice Hall of India, 2008.

REFERENCE BOOKS:

1. Milos Ercegovac, Jomas Lang, “Introduction to Digital Systems”, Wiley publications, 1998.2. John M. Yarbrough, “Digital logic: Applications and Design”, Thomas-Vikas Publishing House, 2002.3. R.P.Jain, “Modern digital Electronics”, 3rd Edition, TMH, 2003.4. William H. Gothmann, “Digital Electronics”, Prentice Hall, 2001.


Max Marks : 80 Exam Duration : 3 Hrs



(Distribution may be 20% Theory & 80 % Numericals)



SBMX1005 BIOFLUIDS AND BIOMECHANICSL T P Credits Total Marks

3 0 0 3 100

UNIT I BIOMECHANICS 10 hrs.

Newton’s Laws, Mechanical Properties -Stress, Strain, Elasticity, Shear, Tension, Compression, PlasticDeformation, Creep, and Fatigue. Microstructure. Mechanical testing of biomaterials-UTM-Basic Engineering mechanics,Resolution of forces, Basic assumptions and Limitations.

UNIT II FLUID MECHANICS 10 hrs.

Viscosity-Definition,properties. Types of fluids- Newtonian fluid, Non- Newtonian fluid,Types of fluid flow.Poiseulle’sequation. Visco-elasticity-Models., Vascular tree, Flow properties of Blood, Physical, Chemical and Rheological propertiesof blood, Apparent and Relative viscosity.

UNIT III HUMAN LOCOMOTION 10 hrs.

Anthropometric Characteristics. Gait analysis. Goniometry. Foot Pressure Measurements-Pedobarograph-Forceplatform. Mechanics of foot. Arthritis-Biomechanical treatment

UNIT IV HARD AND SOFT TISSUE MECHANICS 10 hrs.

Biomechanics of upper extremities-Elbow, Shoulder. Biomechanics of lower extremities-Hip and Knee.-TissueMechanics-Mechanical Properties of Tissues, Biological materials, Properties of Cortical, Cancellous Bone. Soft Tissueproperties Mechanical testing of Soft tissue.

UNIT V SPORTS MECHANICS 10 hrs.

Application of biomechanics to neuromuscular fitness, gymnastics. Application of aerodynamics in sports,hydrodynamics in swimming. Analysis of throw and push patterns.

TEXT BOOKS:1. Susan J Hall, “Basic Biomechanics”, Mc Graw Hill, 1999

REFERENCE BOOKS:1. Y. G. Fung “Biomechanics”, Springer-verlag New York Inc, 19902. Joseph Bronzino “Hand book of Biomedical Engineering”, 2nd Edition, Springer, 20003. Buddy Ratner etal., “Biomaterials Science – An Introduction to Materials in Medicine”, Academic Press, San Diego, 1996.







SBMX1006DIGITAL SIGNAL PROCESSING & ITS

APPLICATIONL T P Credits Total Marks

3 1 0 4 100

UNIT I INTRODUCTION 10 hrs.Characterization and classification of signals-examples of signals-continuous versus discrete signals-analog versus

digital signals – convolutions – sampling and quantization-concepts of signal processing-typical applications- advantagesof digital signal processing compared with analog processing – Applications of signal processing in BiomedicalEngineering.

UNIT II DISCRETE TIME SYSTEMS 10 hrs.Representations – classifications – Analysis of Discrete-Time Linear Invariant Systems- Z-Transform – Inverse

Z transform - Properties

UNIT III FREQUENCY ANALYSIS OF SIGNALS 10 hrs.Discrete Fourier Transform and its properties – computation of DFT – Radix-2 FFT algorithms – DIF and DIT

algorithms. Examples of Biomedical signal processing – Estimation of heart rate in ECG (Harmonic Analysis) – Filteringin Ultrasound (Matched and Wiener filter) – Analysis of EMG signal (Independent component analysis).

UNIT IV FIR FILTER DESIGNING 10 hrs.Digital Filters: FIR filters-designing of FIR filters – Hamming window – Hanning window functions – Rectangular

Window

UNIT V IIR FILTER DESIGN 10 hrs.Butterworth and Chebyshev Filters – Frequency transformation in analog and digital domain, Realization of digital

filters – Direct form I and II.

TEXT BOOK:1. Ramesh Babu, “Digital Signal Processing”, 6th Edition, Scitech Publications, 2008. (Unit-I,II,IV.V)

REFERENCE BOOKS:1. Salivahanan, “Digital Signal Processing”, Tata Mc Graw Hill, 20002. John G. Proakis,Vinay K. Ingle, John G. Proakis “A Self-Study Guide for Digital Signal Processing”, 20073. Nagoorkani, “Digital Signal Processing”, 5th Edition, RBA Publications, 2000.4. Alan V. Oppenheim, Ronald W. Schafer, “Digital Signal Processing”, Prentice-Hall, 19755. Eugene N. Bruce, “Biomedical Signal Processing and Signal Modeling” John Wiley & Sons, 2000.


Max. Marks: 80 Exam Duration: 3 hrsPART A : 2 Questions from each unit, each carrying 2 marks 20 marksPART B : 2 Questions from each unit with internal choice, each carrying 12 marks 60 marks Questions May ask in Part B as 20 % Theory 80 % Problem



SCSX4017 PROGRAMMING IN C++ LABL T P Credits Total Marks

0 0 2 1 50

1. Write a program to find the area of square, rectangle, circle using function overloading concept.

2. Write a program to change the sign of an operands using unary operator overloading concept.

3. Write a program to add two complex numbers using binary operator overloading concept.

4. Implement parametrized constructor, default conctructor, copy constructor and destructor

5. Write a program to enter the sale value and print the agent’s commission using single inheritance.

6. Write a program to count the words and characters in given text using virtual function.

7. Write a program to merge two files into one single file

8. Write a program to sort the numbers using class templates

SECX4045 DIGITAL SYSTEM LABL T P Credits Total Marks

0 0 2 1 50

1. Verification of Logic Gates.

2. Design of Half Adder and Full Adder.

3. Code convertors.

4. Design of Encoder and Decoder.

5. Design of Multiplexer and Demultiplexer.

6. Design of Comparator.

7. Verification of State Transition of Flip Flops.

8. Design of Johnson and Ring Counter.

9. Design of Asynchronous Counter.

10. Design of Shift Registers.

SBMX4004 IMMUNOLOGY & PATHOLOGY LABL T P Credits Total Marks

0 0 4 2 100

Agglutination Test

1. ABO blood grouping

2. Detection of CRP in human serum

3. Pregnancy test

4. Determination of Anti-Streptolysin O antibodies

5. Detection of Rheumatoid factor

6. Widal slide test

7. Widal tube test.

Precipitation Test

8. Ouchterlony Double Diffusion method

9. Immuno Electrophoresis techniques.

Pathology Lab

10. Identification and characterization of various infected tissues.



SMTX1013DISCRETE MATHEMATICS AND NUMERCIAL

METHODS(Common to BIO GROUPS & IT)


3 1 0 4 100

UNIT I LOGIC 10 hrs.

Statements - Truth tables – Connectives – Equivalent Propositions - Tautological Implications - Normal forms -Predicate Calculus, Inference theory for Propositional Calculus and Predicate Calculus.

UNIT II SET THEORY 10 hrs.

Basic concepts of Set theory - Laws of Set theory - Partition of set, Relations - Types of Relations: Equivalencerelation, Partial ordering relation - Graphs of relation - Hasse diagram, Functions: Injective, Surjective , Bijectivefunctions, Compositions of functions, Identity and Inverse functions.

UNIT III GROUP THEORY 10 hrs.

Semi group and Monoid (definition and examples only) – Groups – Properties of groups – Subgroups - Cyclicgroups – Cosets - Lagrange’s theorem.

UNIT IV INTERPOLATION, NUMERICAL DIFFERENTIATION & INTEGRATION 10 hrs.

Interpolation – Gregory Newton’s Forward and Backward Interpolation for equal intervals - Lagrange’s Interpolationfor unequal intervals - Numerical differentiation: Newton’s forward and backward formula to compute the derivatives -Numerical Integration: Trapezoidal rule, Simpson’s 1/3rd rule and Simpson’s 3/8th rule.

UNIT V NUMERICAL METHODS FOR SOLVING EQUATIONS 10 hrs.

Numerical Solution of algebraic and transcendental equations: Regula Falsi method, Newton Raphson method& Secant method. Numerical Solution of simultaneous linear algebraic equations: Gauss Jordan method, Crout’s method,Gauss Jacobi method & Gauss Siedel method.

TEXT / REFERENCE BOOKS:1. Tremblay. S. Manohar. R. Discrete mathematics structure with application to computer science- McGraw-Hill, 1975.2. Kenneth H. Rosen, Discrete mathematics and its applications, 6th Edition, McGraw-Hill, 2007.3. Venkatraman M K, Discrete Structures, National Pub. Co, Madras. 1992.4. Kandaswamy P & Co., Numerical Methods, S.Chand Publications, Chennai 2009.5. Venkataraman M K, Numerical Methods in Science and Engineering, National Pub. Co, Madras. 1992.







SBMX1007 RADIOLOGYL T P Credits Total Marks

3 0 0 3 100


Radioactive elements, Radioactive decay, alpha decay, beta decay, positron decay, decay energy and half-life.Heisenberg uncertainty principle-Radiation units-Roentgen, Rad - rem - sievert-X ray film processing, Intensifyingscreens.

UNIT II RADIATION IMAGING TECHNIQUES 10 hrs.

Fluoroscopy, Angiography, Image intensifier, PET, SPECT, collimators, grids - bucky grids.

UNIT III RADIATION THERAPHY INSTRUMENTS 10 hrs.

Radioisotopes in medicine – COBALT-60, linac, gamma camera, Nuclearscintigraphy, ISODOSE Chart.

UNIT IV INTRODUCTION TO LASERS 10 hrs.

Laser chart - Einsten’s coefficient’s – its significance-population inversion - NdYAG – He - Ne CO2 laser –Holography –Recording & Reconstruction.

UNIT V EFFECTS OF RADIATION 10 hrs.

Protective barrier-primary & secondary somatic & genetic effects of radiation-LD 50/30 effect of radiation on skin,blood forming organs, Radiation carcinogenic, permissible, occupation aldoses, dosimetry.

TEXT BOOKS:1. Thomas S. Curry, III, James E. Dowdey, Robert C. Murry JR., Christensen, "The Physics of Diagnostic Radiology", 4th Edition,

Lea&Febiger, 19902. W.T Meridith & J.B massey, "Fundamental Physics of Radiology", 2nd Edition, Wright, 1972.

REFERENCE BOOKS:1. Gopal,B.Saha , “Physics & Radiology of Nuclear Medicine”, 2nd Edition, Springer, 20062. R.S Khandpur, “Handbook of Biomedical Instrumentation”, Tata McGraw-Hill Publishing Company Ltd, New Delhi, 1997.







SBMX1008 ARTIFICIAL ORGANS AND PROSTHESISL T P Credits Total Marks

3 0 0 3 100


Evolution of organ replacement technology. Organ replacement outlook, Biology of transplantation of tissueproducts matching. Types of tissue grafts, design considerations, evaluation process.

UNIT II ARTIFICIAL ORGANS 10 hrs.

Artificial heart and lung assist devices, Cardiac pace makers, Pacemaker Implantation, cardioverter. Artificialblood, artificial skin, artificial pancreas.

UNIT III ARTIFICIAL KIDNEY AND DEVICES 10 hrs.

The Nephron and Mass Transfer, artificial kidney, dialysis membrane, Dialysis Procedure and the Dialysis System,Dialyzer Cartridge Reuse.

UNIT IV TRANSPLANTATION 10 hrs.

Transplants types, immunological considerations, blood transfusions. Individual organs – Kidney, liver, heart, lung,bone, skin, hair and pancreas. Regeneration and ethical considerations.

UNIT V PROSTHETIC DEVICES 10 hrs.

Engineering concerns-pressure gradient, effective orifice area. Regurgitation, flow, patterns and turbulent shearstresses. Heart valve prosthesis – mechanical and tissue valves, orthotic devices, fundamentals and engineeringprinciples of limb prosthesis.

TEXT BOOK:1. Gerald E. Miller, “Artificial Organs”, 1st Edition, A Publication in the Morgan & Claypool Publishers series, United States of America,

2006.

REFERENCE BOOKS:1. J.B. Park and R.S. Lakes, “Biomaterials: An Introduction” 2nd Edition, Plenum press, New York, 1992.2. Joseph D Bronzino, “The Biomedical Engineering hand Book” Vol-11, CRC press, 2000.







SBMX1009 ANALYTICAL INSTRUMENTATIONL T P Credits Total Marks

3 1 0 4 100

UNIT I INTRODUCTION TO ANALYTICAL INSTRUMENTS 10 hrs.

Analytical methods and instrumentation types, Electromagnetic spectrum, Interaction of radiation with matter,Absorption spectra, Beer-Lambert’s Law. Spectrophotometers: UV and visible ranges, single and Double BeamInstruments, FTIR and Raman Spectra – Basic principles, biomedical applications.

UNIT II AUTOMATED BIOCHEMICAL ANALYSIS 10 hrs.

System concepts – System Components - sampler control units - sampling mechanisms, dialyzer - samac-II.

Gas Analyzers: Paramagnetic Oxygen Analyzer.

UNIT III MASS SPECTROMETER 10 hrs.

Magnetic deflection - Time of flight - quadrupole - Basic Principles and biomedical applications.

RadioChemical Analytical Instruments: Radiation types - Ionization chamber - GM Counter - Proportional counter.

UNIT IV MICROSCOPIC TECHNIQUES 10 hrs.

Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM)and Scanning Tunneling Microscopy (STM) – Basic Principles and Applications.

UNIT V CHROMATOGRAPHY 10 hrs.

Principles, Types of chromatography - Liquid Chromatography - High Pressure Liquid Chromatography –applications in biomedical field.

TEXT BOOK:1. R.S. Khandpur, “A Handbook of Analytical Instrumentation”, 2nd Edition, Tata McGraw Hill Publication, 2009.

REFERENCE BOOKS:1. D.A. Skoog, F.J. Holler & T.A. Nieman, “Principles of Instrumental Analysis”, 5th Edition, Saunders College Publishing, 19982. Williard H.H., Merrit, Dean J.A, Seattle F.L, “Instrumental Methods of Analysis”, 7th Edition, CBS, 2007.3. Ewing G.W., “Instrumental Methods of Analysis”, McGraw Hill, 19924. Robert D. Braun “Introduction to Instrumental Analysis”, McGraw Hill, 1987.







SECX1015 MICROPROCESSOR AND MICROCONTROLLERL T P Credits Total Marks

3 0 0 3 100

UNIT I INTRODUCTION TO INTEL 8085 10 hrs.

Evolution of Microprocessor – Architecture – Instruction format – Addressing modes – Basic timing diagram –Input – Output – Interrupt System – 8085 based system design

UNIT II INTEL 8085 INTERFACING 10 hrs.

8255 Programmable Peripherals Interface Architecture & various modes of operation – 8251 USART Architectureand programming features – 8237 DMA Controller Architecture & Programming features

UNIT III 16 – BIT MICROPROCESSOR 10 hrs.

Architecture of 8086 – Registers set of 8086 – Special function of general purpose register – Addressing modes– Instruction set – pin diagram of 8086 – Timing diagram – Minimum and Maximum mode of operation

UNIT IV MICROCONTROLLER 10 hrs.

Introduction to 8–bit Microcontrollers – 8051 Microcontroller Architecture – Registers set of 8051 – modes ofTimer operation – Serial port operation – Interrupt Structure of 8051 – Memory and Input/Output Interfacing of 8051

UNIT V APPLICATIONS 10 hrs.

Analog to Digital Converter Interfacing – Digital to Analog Converter Interfacing – Stepper motor interfacing –TTL to RS232 Conversion – RS232 to TTL Conversion – Interfacing EPROMs & SRAMs.

TEXT BOOKS:1. Ramesh Goankar, “Microprocessor Architecture, Programming and its applications with 8085”, Pentam International Publications, 2007.2. Kennith J. Ayala, “Microcontroller”, 3rd Edition, Thomson Delmar Learning, 2005.

REFERENCE BOOKS:1. Dougles V, Hall, “Microprocessor and Interfacing”, 2nd Edition, Tata MC Graw Hill Publication, 2006.2. Charles M. Gilmore, “Microprocessor Principle and application”, 2nd Edition, Mc Graw Hill Publication, 2007. 3. NagoorKani, “Microprocessor & Applications”, 2nd Edition, RBA Publication, 2010.4. Renu Singh and B.P Singh, “Microprocessor Interfacing & Applications”, 2nd Edition, New Age, 2006.







SECX1030 BIOSIGNAL CONDITIONINGL T P Credits Total Marks

3 1 0 4 100

UNIT I INTRODUCTION TO OP-AMP 10 hrs.

Introduction, Signal conditioning, 741 General purpose OPAMP: ideal characteristics, offset voltages and currents.Open & Closed Loop Configuration. BASIC OP-AMP APPLICATIONS: Inverting, Non-Inverting, Summing, VoltageFollower, Integrator, differentiators, Log & Anti-Log Amplifiers, Differential Amplifiers, CMRR.

UNIT II AMPLIFIERS 10 hrs.

Power Amplifiers, Three OP-AMP Systems - Instrumentation amplifiers, Bridge Amplifiers. Biopotential Amplifiers;Properties desired, Isolation Amplifiers: Battery Powered, Carrier, optically Coupled, Current Loading, Chopper Stabilizedamplifier, Input Guarding.

UNIT III OSCILLATORS AND SIGNAL GENERATORS 10 hrs.

Comparator, Schmitt Trigger, Linear Half-wave Rectifiers, Precision rectifiers, Peak detectors, RC phase shiftoscillator, Wein Bridge oscillator, Signal generators:Monostable, Astable multivibrators, Sawtooth, Triangular, Sine Wave,Square Wave Generators.

UNIT IV FILTERS 10 hrs.

Introduction, Analog Filters, Active filters, Low Pass Filters, High Pass Filters, Band Pass Filters, Band RejectFilters, All Pass filters and high Order filters and their Design.

UNIT V A/D AND D/A CONVERTERS 10 hrs.

Sample and Hold circuit - D/A converters: Resistive divider and ladder networks, A/D converters: Counting type,Successive approximation, parallel comparator. Voltage to Current Converter, 555 Timer and its applications: Astableand Monostable multivibrator.

TEXT BOOKS:1. Ramakant A. and Gayakward, “Operational Amplifiers & Linear Integrated Circuits”, 4rd Edition, Prentice Hall of India, 20062. Joseph J. Carr & John M. Brown, “Introduction to Biomedical Equipment Technology”, 4th Edition, Pearson Education Pvt. Ltd, 2001.

REFERENCE BOOKS:1. Roy Choudhary, “Linear Integrated Circuits”, 3rd Edition, New Age International Publishers, 20092. John P.Bentley, “Principles of Measurement System”, 3rd Edition, Longman Science & Technology, 1995.3. Jacob Mill man, “Micro Electronics”, McGraw-Hill, 1987.4. Robert Coughlin and Fredrer, “Operational Amplifiers & Linear Integrated Circuits”, 5th Edition, Prentice Hall, 1997.







SBAX1001PRINCIPLES OF MANAGEMENT AND

PROFESSIONAL ETHICSL T P Credits Total Marks

3 0 0 3 100

UNIT I MANAGEMENT FUNCTIONS & STRUCTURE 10 hrs.

Management – Definition – Basic Function – Contribution of Taylor & Fayol. Types of structure – Line, staff,Functional, Committee, Project & Matrix – Structures.

Departmentalization – Centralization – Decentralization – span of control. Management By Objectives –Management By Exception.

UNIT II MANAGEMENT OF ORGINASATION 10 hrs.

Forms of Business / Industrial Ownership – Sole Trader, Partnership, Company, Performance Appraisal – BasicPrinciples – Pitfalls – Methods to Overcome. Industrial Safety – Causes of Accidents – Cost of Accident – How tominimize Accidents. Plant Layout & Maintenance – Need, Types & Managerial Aspects.

UNIT III ORGANISATIONAL BEHAVIOUR 10 hrs.

OB – Definition – Nature & Scope – Contributing Disciplines – Importance of OB to Managers. Personality –Definition – Theories – Factors Influencing Personality. Motivation – Definition – Theories. Theory X & Y – TransactionalAnalysis. Morale & Job Satisfaction – Factors Influencing Job Satisfaction.

UNIT IV GROUP DYNAMICS 10 hrs.

Group – Definition – Types – Determinants of Group Cohesiveness – Communication – Process – Barriers –Effective Communication. Leadership Theories – Factors Contributing to Effective Leadership – Role of Trade Unionin Organizations – Functions of Trade Union – Why Trade Union is required? – Types of Trade Union.

UNIT V PROFESSIONAL ETHICS 10 hrs.

Ethics in Workplace – Formulation of Ethics – Managerial Ethics – Managing Ethical Behaviour – Codes ofEthics – Encouraging Ethical Behaviour – Social Responsibility – Spirituality.

TEXT / REFERENCE BOOKS1. Gupta C.B., Management Theory and Practice, 14th Edition, Sultan Chand & Sons, 2009.2. Dr. Prasad L.M., Principle & Practice of Management, 7th Edition, Sultan Chand & Sons, 2008.3. Aswathappa, Organisational Behaviour, 8th Edition, Himalaya Publishing House, 2010.4. Dr. Prasad L.M., Organisational Behaviour, 4th Edition, Sultan Chand & Sons, 2008.5. Harold Koontz, Principles of Management, 1st Edition, Tata McGraw Hill, 2004.







SBMX4005 MEDICAL ELECTRONICS LABL T P Credits Total Marks

0 0 4 2 100

1. Study of operational amplifier IC 741.

2. Characteristics of operational amplifier IC 741.

3. Inverting and non-inverting mode of operation.

4. Operational amplifier as summer and subtractor.

5. Operational amplifier as integrator and differentiator.

6. Instrumentation amplifier.

7. 555 Timer

8. Active high pass filter (Second order)

9. Active Low Pass filter (Second order)

10. Narrow band pass filter.

11. RC phase shift oscillator.

12. Comparator.

13. Squaring Circuit.

14. Half wave rectifier.

15. Current to voltage converter.

16. Voltage to current converter.

SECX4045 MICROPROCESSOR AND MICROCONTROLLER LABL T P Credits Total Marks

0 0 4 2 100

1. Study of 8-bit microprocessor and interfacing facilities.

2. Addition & subtraction (8-bit & 16-bit numbers).

3. Multiplication and Division (8-bit & 16-bit numbers).

4. Sorting ‘n’ number.

5. Code converters.

6. Interfacing of D/A and A/D converters.

7. Measurement of frequency using 8253.

8. Study of 8-bit Micro controllers and interfacing facility.

9. Addition and subtraction – with carry and without carry in 8-bit micro controllers.

10. Code conversion using micro controllers.

11. Interfacing 8279 with MC.

12. Stepper Motor interfacing with microprocessor and micro controllers.

13. Traffic control interfacing with microprocessor and micro controllers.

14. Transfer external memory data from internal memory area in micro controllers.



SMEX1017RESOURCE MANAGEMENT TECHNIQUES

(Common to All Branches)


3 0 0 3 100

UNIT I INTRODUCTION AND LINEAR PROGRAMMING 10 hrs.

Operations Research(OR)-Nature-Characteristics-Phases.-Role of OR in Decision making- Outline of OR ModelsLinear Programming – Formulation of Linear Programming Problems –Solution by graphical method, simplex method,and big M methods – Applications of O.R. in production management

UNIT II TRANSPORTATION AND ASSIGNMENT MODEL 10 hrs.

Transportation problem – Initial feasible solution- Northwest corner method, Least Cost method, Vogel’sapproximation method – Test for optimality-MODI method

Assignment problems- Hungarian assignment models- Travelling salesman problems

UNIT III RESOURCE SCHEDULING AND NETWORK ANALYSIS 10 hrs.

Problem of Sequencing – Problem with N jobs and 2 machines, 3 jobs and M machines. Project Management– Basic concepts – Case studies – Network construction and scheduling, Program evaluation and resource levelingby network techniques, time – Cost trade off.

UNIT IV INVENTORY CONTROL AND SIMULATION 10 hrs.

Inventory Control – Various Types of inventory models – deterministic inventory models – Production model,Purchase model– with and without shortage- EOQ – Buffer stock – Shortage quantity, Probabilistic inventory models– Quantity Discount and Price Breaks Simulation – Use, advantages & limitations, Monte –Carlo simulation, applicationto queuing, inventory & other problems

UNIT V QUEUEING THEORY, GAME THEORY AND REPLACEMENT MODELS 10 hrs.

Queuing theory – Poisson arrivals and exponential service times, Single channel models only. Game theory-Payoff matrix, competitive games with pure strategy, minimax criterion, principles of dominance and mixed strategiesReplacement policy for items whose maintenance cost increases with time- Consideration of money value- Replacementpolicy- Individual, Group replacement of items that fail completely

TEXT BOOK:1. Kanti Swarup, P.K.Gupta, & Manmohan., "Operations Research", 7th Edition, S. Chand & Sons, 1994.

REFERENCE BOOKS:1. K.V.Mital and C.Mohan,” Optimization Methods in O.R and System Analysis “, New Age International Publishers., 19962. S.D.Sharma,”Operations Research”, Kedarnath Ramnath& Co, 2002.3. Hamdy A. Taha,” Operations Research”, 5th Edition., PHI, 19954. Hiller & Liberman,”Introduction to operation research”, 5th Edition., McGraw Hill, 2001.5. Ravindran,Phillips&Solberg, “Operations Research: principles and practice”, 2nd Edition., Wiley India Ltd, 2007







SEEX1029 BIOLOGICAL CONTROL SYSTEML T P Credits Total Marks

3 1 0 4 100

UNIT I SYSTEM CONCEPTS 10 hrs.

Types of systems - Open loop systems, closed systems, Effects of feed back, Block diagram algebra and Signalflow graphs.

UNIT II TIME RESPONSE ANALYSIS OF CONTROL SYSTEMS 10 hrs.

Standard test signals, Time response of first order and second order systems, Time domain specification, steadystate errors and error constants. Concept of stability and Algebraic Criteria:

UNIT III THE CONCEPT OF STABILITY & ROOT LOCUS TECHNIQUE 10 hrs.

The concept of stability, Routh stability criterion qualitative stability and conditional stability. the Root locus concept,construction of root loci.

UNIT IV FREQUENCY RESPONSE ANALYSIS 10 hrs.

Frequency response of the systems - Correlation between time and frequency responses - Gain and phasemargins, Bode plots. Nyquist stability Criteria: Polar Plots, Nyquist stability Criteria, Relative stability using Nyquistcriteria.

UNIT V BIOMEDICAL APPLICATIONS 10 hrs.

Mathematical Models of Physical systems: Differential equations, Transfer functions and block diagrams of simpleelectrical networks, Translational and Rotational mechanical systems. Examples of Biological control Systems:Cardiovascular Control System, Endocrine Control Systems, Pupil Control System, Skeletal Muscle Servomechanism,Oculo - motor system, sugar level Control Mechanism.

TEXT BOOKS:1. J. Nagrath and Gopal, "Control Systems Engineering", New Age International (P) Limited, Publishers, 2nd Edition.2. Kaushia Ogata, "Modern Control Engineering", 3rd Edition, Prentice Hall of India Pvt Ltd, 1998.3. Milsum John H, "Biological Control System Analysis", 2nd Edition, McGraw Hill Publications, 1996.

REFERENCE BOOKS:1. M. Gopal, "Control Systems: Principles and Design", Tata McGraw-Hill publishing company Ltd, 19972. N.K Sinha, "Control Systems", 3rd Edition, New Age International (P) Limited Publishers, 1998.3. Milhom T.H., "Applications of Control Theory to Physiological Systems", Saunder Publications, 1980.4. Prof. NageswaraRao,"Control Systems", 3rd Edition, A.R. Publications, 2003.





(Distribution may, be 30% Theory & 70% Numericals)



SECX1067 MEDICAL IMAGE PROCESSINGL T P Credits Total Marks

3 0 0 3 100

UNIT I IMAGE FUNDAMENTALS 10 hrs.

Structure of Human Eye - Image formation in eye. Fundamental steps on Image processing – components ofimage processing system. Basic relationship between pixels Image sensing and acquisition. Image formation model,Image processing, Image sampling and quantization, aliasing, Zooming and shrinking of digital images.

UNIT II IMAGE TRANSFORMS AND COLOR IMAGE 10 hrs.

1D DFT, 2D DFT, Cosine, Sine Hadamard, KL transform and their properties. Color image processing – Colormodels, Pseudo color image processing, full color image processing

UNIT III IMAGE ENHANCEMENT 10 hrs.

Enhancement by point processing – Simple intensity transformation – Histogram processing – Image subtraction– Image averaging. Spatial filtering – Smoothing filters, sharpening filters. Enhancement in frequency domain – Lowpass filtering – High pass filtering

UNIT IV IMAGE RESTORATION 10 hrs.

Model of Image degradation / restoration process. Restoration using spatial filtering – Mean filter-Medium filter– Max and Min filter – Midpoint filter. Noise reduction using Frequency domain filtering – Band Reject Filter, Bandpass filter – Notch filter. Inverse filtering, least mean square filter. Edge and Line Detection

UNIT V IMAGE COMPRESSION 10 hrs.

Data Redundancy, Image compression model - Source Encoder and Decoder, Channel encoder and decoderInformation channel – Fundamental coding theorems – Noiseless coding – Noisy coding theorem.

TEXT BOOK:

1. Raphael C. Gonzalez / Richard E. Woods, “Digital Image Processing”, Prentice Hall India, 2nd Edition, 2002.

REFERENCE BOOKS:

1. Anil K.Jain, “Fundamentals of Digital Image Processing”, 2nd Edition, Prentice Hall India, 1995.2. William K.Pratt, “Digital Image Processing” 3rd Edition, John Wiley, 20043. B. Chanda and Durtta Mujamdar, “Digital Image Processing and Analysis”, 1st Edition Prentice Hall of India, 2000







SBMX1010 DIAGNOSTIC INSTRUMENTATIONL T P Credits Total Marks

3 0 0 3 100

UNIT I BIOMEDICAL RECORDER 10 hrs.

Basic Measurement system, ECG-Lead configuration-Instrumentation set-up – effects of artifacts. EEG – 10-20Electrodes configuration – Instrumentation – recording of Evoked potentials, EMG – Measurement of nerve conductionvelocity. ERG, EOG, PCG, Holter Monitoring.

UNIT II IMAGING EQUIPMENTS 10 hrs.

X-Ray machine, CT – Scanning system, processing unit, viewing part & storage unit. MRI – The magnet, RFtransmitter system, Gradient system, imager system, Advantages. Ultrasonic imaging systems – A Scan, B Scan, TMMode Scan, Biomedical Applications Thermographic Equipment.

UNIT III FLOW METERS 10 hrs.

Flow meters and CO2 Measurement, Electromagnetic flow meters, Ultrasonic Blood flow meters, Laser DopplerBlood flow meters, NMR Blood flow meters. Indicator Dilution method, Dye dilution method, Thermal dilution method.

UNIT IV PATIENT MONITORING SYSTEMS 10 hrs.

BP measurement – Direct and indirect method, pulse rate analysis, temperature measurement, Respiration Rate,Biomedical applications, Central monitoring system. Endoscope, Foetal Monitor, Oximetry.

UNIT V AUDIO AND VISUAL EQUIPMENTS 10 hrs.

Basic Audiometer – Pure tone and speech, Conventional hearing aids, Basic Spirometry. Test Standard, Trialcase lenses, Auto Refractometer, Dioptron, Retinoscope, Optometric Instrument.

TEXT BOOKS:1. Khandpur R.S., “Handbook of Biomedical Instrumentation ” Tata McGraw Hill Publication Company Ltd, New Delhi, 19972. R. AnandaNatarajan, “Biomedical Instrumentation & Measurements”, PHI Publication, 2010.

REFERENCE BOOKS:1. John G. Webster, “Medical Instrumentation”, 3rd Edition, John Wiley & Sons, 2004.2. Cromwell, “Biomedical Instrumentation & Measurements” 2nd Edition, Prentice-hall of India private limited, 2009.3. Carr & Brown, “Introduction to Biomedical Equipment Technology”, 7th Edition, Pearson Education, 2004.4. Alan. H. Tunnacliffe, “Introduction to Visual optics”, ABDO College of Education, 19935. David. B. Henson, “Optometric Instrumentation”, 2nd Edition, Butterworth Heinemann, 1996







SBMX4006 DIAGNOSTIC INSTRUMENTATION LABL T P Credits Total Marks

0 0 4 2 100

1. ECG acquisition using BPL cardiart – 8108 (12 lead)

2. Spirometer

3. Heart rate monitor

4. Phonocardiogram monitor

5. Multi parameter monitoring system

6. Respiration rate apnea monitor

7. EMG monitor (nerve conduction velocity)

8. EEG monitor (32 channel)

9. Ultrasound Doppler

10. Design of pacemaker

11. Medical telemetry system

12. Design of audiometer

13. EOG monitor

14. Blood flow monitor

SECX4040 MEDICAL IMAGE PROCESSING LABL T P Credits Total Marks

0 0 2 1 50

1. Study of basic functions of MAT Lab

2. Arithmetic operations on images, Image Complement.

3. Histogram Processing – Techniques.

4. Image cropping

5. Line and Edge detection

6. FT and DCT of images

7. Contrast stretching, Threshold technique - Enhancement

8. Adaptive filters. Sharpening and smoothing Filters.

9. Restoration filters- Median Filtering, Mean, Min-Max, Band Pass / Rejection, and Notch.

10. Compression Techniques.

SECX4041 DIGITAL SIGNAL PROCESSING LABL T P Credits Total Marks

0 0 2 1 50

1. Representation of basic signals

2. Sampling and Quantization

3. Fast Fourier transform of the signals

4. Circular convolution and Linear convolution

5. Digital IIR filter (Butter worth &Chebyshev)

6. FIR filter design (Hamming &Hanning)

7. Correlation of the signals

8. EEG & ECG signal processing basics using MATLAB



SBMX1011 BIOMATERIALSL T P Credits Total Marks

3 0 0 3 100


Biomaterials – Overview, Classification of biomaterials, Interfacial Phenomena and tissue response to biomaterials,Metals and alloys for orthopedic implants-Stainless steel, Cobalt chromium alloy, Titanium and its alloys. Types oforthopedic fixation devices-pins, screws and plates, Intra Medullary and spinal nails.

UNIT II REPLACEMENT AND FIXATION 10 hrs.

Bioelectric effect, Interface Problems with artificial joints and various fixation methods, Hard tissue replacements– total hip and knee joint replacements. Dental implants – materials, types and designs

UNIT III USES AND APPLICATIONS OF POLYMERS 10 hrs.

Polymers in biomedical use, Hydrogels, silicone rubber, biodegradable polymers, Composites – Types andApplications.

UNIT IV INTRODUCTION TO OPTHALMOLOGY 10 hrs.

Ophthalmology- introduction, contact lenses, eye shields and artificial tears. Corrosion, Biocompatibility, BiologicalTests. Material surface characterization

UNIT V BIOCERAMICS 10 hrs.

Bioceramics, types and – bioactive resorbable, non – resorbable, bioceramic coatings on metallic and implantsand bone bonding reactions on implantation. Hydroxyapatite – properties and applications.

TEXT BOOKS:

1. Sujata V Bhat, “Biomaterials”, Narosa Publishing House, New Delhi, 2002. 2. F. Silver and C. Dillon, “Biocompatibility: Interactions of Biological and Implantable Materials” Vol. 1, VCH Publishers, New york,

1989

REFERENCE BOOKS: 1. A.F. Von Recum, “Handbook of Biomaterials Evaluation – Scientific, Technical and Clinical Testing of Implant Materials”, 2nd Edition,

Taylor & Francis, Philadelphia, 1999. 2. J.B Park and R.S Lakes “Biomaterials: An Introduction” 2nd Edition, Plenim press, New York, 1992. 3. Joseph D Bronzino, “The Biomedical Engineering Hand Book”, Vol – 11, CRC press, 2000.







SECX1068 BIOTELEMETRYL T P Credits Total Marks

3 0 0 3 100

UNIT I INTRODUCTION TO TELEMETRY PRINCIPLE 10 hrs.

Basic system – Classification – Non electrical telemetry systems – Voltage and Current telemetry systems –Local transmitters and Converters – Frequency telemetering – Power Line carrier communication (PLCC) .

UNIT II AMPLITUDE MODULATION 10 hrs.

Modulation – Need of modulation, Mathematical representation of AM (AM, DSB – SC – AM, SSB – SC AM,VSB AM) – Frequency spectrum – Bandwidth – power relation - Generation of FM – square law modulator andBalanced modulator – AM transmitter – Detection of AM: square law detector – envelope detector – AM receiver –TRF and super heterodyne receiver.

UNIT III ANGLE MODULATION 10 hrs.

Mathematical representation – Frequency spectrum – Band Width Generation of FM - Varactor Diode modulator– Armstrong modulator – FM transmitter – FM detection: Foster seely discriminator – Ratio detector – FM receiver.

UNIT IV DIGITAL MODULATION AND MULTIPLEXING 10 hrs.

Sampling – Quantization – Pulse Modulation: Overview of PAM, PPM, PWM and Delta modulation – DataTransmission: Overview of ASK, FSK, PSK and QPSK - Multiplexing: Overview of Time Division Multiplexing, FrequencyDivision Multiplexing – Modems – MODEM protocol.

UNIT V APPLICATIONS 10 hrs.

Wireless Telemetry – Single Channel Telemetry systems – Multi channel Telemetry systems – Multi PatientTelemetry – Implantable Telemetry Systems.

TEXT BOOKS:1. K. S. Srinivasan, “Communication Theory”, Anuradha Publication, 2007.2. R. S. Khandpur, “Hand Book of Biomedical instrumentation”, Tata McGraw Hill Publication Company Ltd, New Delhi, 1997

REFERENCE BOOKS:1. Taub and Schilling “Principles of Communication”, 3rd Edition, Tata McGraw Hill Publication, 2008.2. D. Patranabis, “Telemetry Principles”, 1st Edition, Tata McGraw Hill Publication, 1999.







SBMX1012 REHABILITATION ENGINEERINGL T P Credits Total Marks

3 0 0 3 100

UNIT I INTRODUCTION TO REHABILITATION 10 hrs.

Introduction Concepts and principles of rehabilitation engineering, Ergonomics - Positioning anatomical site,simplicity and intuitive operation, adaptability and flexibility, mental and chronological age appropriateness. Basics andFundamentals in Rehabilitation and its applications. Knowledge of disability act 1995 for physically disabled, visuallyimpaired, hearing impaired and others.

UNIT II MOTOR REHABILITATION 10 hrs.

Orthopedic prosthetics and orthotics in Rehabilitation Fundamentals, Applications: Computer Aides Engineeringin customized component design. Intelligent prosthetic knee. A hierarchically controlled prosthetic hand. A self-aligningorthotic knee joint. Externally powered and controlled orthotics and prosthetics: FES System: Restoration of handfunction; restoration of standing and walking. Hybrid Assistive systems (HAS) Active prostheses. Active Above kneeProsthesis. Myoelectric hand and arm prostheses. The MARCUS Intelligent Hand Prosthesis

UNIT III WHEELED MOBILITY 10 hrs.

History and Categories of Wheelchairs. Wheelchair Structure and Component Design. Ergonomics of wheel chairpropulsion. Power Wheelchair Electrical System. Personal transportation. Auxiliary derives and system.

UNIT IV SENSORY AUGMENTATION AND SUBSTITUTION 10 hrs.

Visual System: Visual augmentation, Tactual vision substitution. Auditory vision substitution: Auditory System;Auditory augmentation, Cochlear implantation, Visual auditory substitution, Tactual auditory substitution. Tactual system:Tactual augmentation, Tactual substitution, Augmentative communication, Control and Computer Access: AAC; UserInterface: Outputs: Acceleration Techniques.

UNIT V COMPUTER APPLICATIONS IN REHABILITATION ENGINEERING 10 hrs.

Interfaces in Compensation for visual perception. Improvement of orientation and mobility. Computer – assistedlip reading. Brain – computer interface. Computer – Aided Engineering in customized component design. CostEffectiveness of High Vs Low – Technology Approaches; Intervention and other Issues; Environmental Control andAccess to computers.

TEXT BOOK:1. Bronzino, “Biomedical Engineering” Hand Book, 2nd Edition, Volume 1, IEEE Press, 2000

REFERENCE BOOKS:1. Robinson C.J,“ Rehabilitation Engineering”, CRC Press. 19952. Ballabio E. et al,“ Rehabilitation Technology”, IOS Press. 1993.3. Handbook of “Physical Medicine & Rehabilitation”, W.B.Saunders Publication, 2003.4. Hanfredclynes, “Biomedical Engineering System”, McGraw Hill, 1999







SBMX1013 THERAPEUTIC INSTRUMENTATIONL T P Credits Total Marks

3 0 0 3 100

UNIT I PACEMAKER AND DEFIBRILLATOR 10 hrs.

Cardiac Pacemakers - Need for Cardiac Pacemaker - External Pacemakers - Implantable Pacemakers – RecentDevelopments in Pacemaker system analyzer. Cardiac Defibrillators -Need for a Defibrillator - DC Defibrillator -Implantable Defibrillators – Pacer-cardio vector - Defibrillator analysis.

UNIT II INSTRUMENTS FOR SURGERY AND TREATMENT 10 hrs.

Instruments for surgery - principle of surgical diathermy - surgical diathermy machine - safety aspects inElectro-Surgical diathermy Units. Physiotherapy and electrotherapy equipment - High frequency heat therapy - shortwave Diathermy - Microwave diathermy - Ultrasonic therapy unit – Pain relief through Electrical Stimulation – BladderStimulators – Cerebellar Stimulators.

UNIT III HAEMODIALYSIS MACHINE AND LITHOTRIPTERS 10 hrs.

Haemodialysis Machines - Function of the kidneys - Artificial Kidney – Dialyzers - Membrances of haemodialyzers- Haemodialysis machines - Portable Kidney machines. Lithotripters – The stone disease problem - First lithotriptermachine – modern lithotripter systems - Extracorporeal Shockwave Therapy

UNIT IV ANESTHESIA MACHINE AND RADIO THERAPY EQUIPMENTS 10 hrs.

Need for Anesthesia – Anesthesia machine - Electronics in Anesthesia machine. Radiotherapy Equipment - Useof High voltage X-Ray machines - Development of Betatron, Heart lung Machine.

UNIT V VENTILATORS 10 hrs.

Mechanics of Respiration - Artificial Respiration – Ventilators - Types of ventilators - Ventilator terms -Classification of Ventilators – Pressure – volume - flow Diagrams - Modern ventilators - High frequency ventilators.Humidifiers - Nebulizers and Aspirators.

TEXT BOOK:1. R. S. Khandpur, “Handbook of Biomedical Instrumentation”, Tata McGraw Hill Publication company Ltd, New Delhi, 1997

REFERENCE BOOKS:1. Joseph. J Carry and John. J. Brown, “Introduction to Biomedical Equipment Technology” 4th Edition, Pearson Education, 2003 2. John G Webster, “Medical Instrumentation: Application and Design” John Wiley & Sons, 19983. John G Webster, "Bioinstrumentation", John Wiley & Sons, 2004







SCSX1055 FUZZY LOGIC AND NEURAL NETWORKSL T P Credits Total Marks

3 0 0 3 100


Introduction to Fuzzy Set Theory – Basic Concepts of Fuzzy Sets – Classical Set Vs Fuzzy Set – Propertiesof Fuzzy Set – Fuzzy Logic Operation on Fuzzy Sets – Fuzzy Logic Control Principles –Fuzzy Relations – FuzzyRules – Defuzzification.

UNIT II FUZZY APPLICATIONS 10 hrs.

Logic Controller – Fuzzification Interface – Knowledge Base – Decision Making Logic – Defuzzification Ineterface– Application Of Fuzzy Logic To Control Of Blood Pressure During Anaesthesia – Cardio Vascular Signals – FuzzyLogic Decision By Fuzzifying Boolean Rule, Fuzzy Logic Patient Deterioration Index.

UNIT III ANN INTRODUCTION 10 hrs.

Fundamentals of ANN – Biological Neurons And Their Artificial Models – Types of ANN – Properties – DifferentLearning Rules – Types of Activation Functions – Training Of ANN – Perceptron Model (Both Single & Multi Layer)– Training Algorithm – Problems Solving Using Learning Rules And Algorithms – Linear Separability Limitation AndIts Over Comings

UNIT IV ANN BASIC CONCEPTS 10 hrs.

Back Propagation Training Algorithm – Practical Difficulties – Counter Propagation Network – Structure &Operation – Training of Kohenen And Grossberg Layer – Applications Of BPN & CPN – Statistical Method – TrainingApplication – Boltzmann Training – Cauchy Training – Hop Field Network And Boltzmann Machine – Speed EnergyFunction – Network Capacity – Applications A/D Converter – Travelling Sales Man Problem – RBF Network

UNIT V ANN ADVANCED CONCEPTS 10 hrs.

BAM – Structure – Types – Encoding And Retrieving – Adaptive Resonance Theory – Architecture Of ART 1&ART 2 – Implementation – Training – Characteristics – Introduction To Optical Neural Network – Cognitron &Neocognitron

REFERENCE BOOKS:

1. Timothy J.Ross, “Fuzzy logic with engineering application”, 1st Edition, Tech India, 2002.2. Jack M. .Zurada, “Introduction to Artificial Neural Systems”, Jaico Publishers, 1997.3. James A. Freeman & Davis Skapura, “Neural Networks”, Pearson Education, 2002.4. Philip D.Wasserman, “Neural computing theory & Practice”, Van Nostrand and Reimhold, 5. Simon Haykin, “Neural Networks - A Comprehensive foundation”, 2nd Edition, Pearson Education, 2005.6. B.Yagnanarayana, “Artificial Neural Networks”, PHI, 1999.7. Drainkov, Hallendoor and Reinfrank, “An introduction to fuzzy control”, 2nd Edition, Springer, 1996.


Max.Marks: 80 Exam Duration: 3 hrs





SBMX1027 VIRTUAL BIOINSTRUMENTATIONL T P Credits Total Marks

3 0 0 3 100


Historical perspective, advantages, block diagram and architecture of a virtual instrument, data-flow techniques,graphical programming in data flow, comparison with conventional programming

UNIT II PROGRAMMING TECHNIQUES 10 hrs.

VIS and sub-VIS, loops & charts, arrays, clusters, graphs, case & sequence structures, formula modes, localand global variable, string & file input.

UNIT III DATA ACQUISITION 10 hrs.

Introduction to data acquisition on PC, Sampling fundamentals, Input/Output techniques and buses. ADC, DAC,Digital I/O, counters and timers, DMA, Software and hardware installation, Calibration, Resolution, Data acquisitioninterface requirements.

UNIT IV INSTRUMENT INTERFACES 10 hrs.

Current loop, RS 232C/RS 485, GPIB, System basics, Interface basics: USB, PCMCIA, networking basics foroffice & industrial application VISA & IVI, image acquisition & processing, Motion Control. ADC, DAC, DIO, DMM,waveform generator.

UNIT V APPLICATION OF VI 10 hrs.

Fourier Transforms, Power spectrum, Correlation methods, windowing & flittering. Application in Process Controlprojects, Major equipments - Oscilloscope, Digital Multimeter, Pentium Computers, temperature data acquisition system,motion control employing stepper motor, Image acquisition and processing.

TEXT BOOKS:1. Gary Johnson, LABVIEW Graphical Programming, 2nd Edition, McGraw Hill, 1997.2. Lisa K. Wells and Jeffrey Travis, LABVIEW for Everyone, PHI, 1997.3. Skolkoff, Basic concepts of LABVIEW 4, PHI, 1998.

REFERENCE BOOKS: 1. Kevin James, PC Interfacing and Data Acquisition: Techniques for Measurement, Instrumentation and Control, Newnes, 2000. 2. S. Gupta, J.P. Gupta, PC Interfacing for Data Acquisition and Process Control, ISA, 2nd Edition, 1994. 3. Technical Manuals for DAS Modules of Advantech and National Instruments. 4. Jerome, Virtual Instrumentation Using LabView, PHI, 2010. 5. Virtual Bio-Instrumentation: Biomedical, Clinical, and Healthcare Applications in LabVIEW BY By Jon B. Olansen, Eric Rosow, Pearson

Education, 2001.







SBMX1014 HOSPITAL MANAGEMENTL T P Credits Total Marks

3 0 0 3 100

UNIT I INTRODUCTION TO ADMINISTRATION 10 hrs.

Evolution of health care systems – Concept of Hospital Management – Role of Administrator – Responsibilitiesof Administrator – Hospital Design – Outlines for establishing Departmental Zones – Hospital Engineering.

UNIT II OUTPATIENT SERVICES 10 hrs.

Organization of Out-Patient Services – Problems encountered in functioning of O.P Department – Organizationof In- Patient Services – Casualty & Emergency Services.

UNIT III ANCILLARY SERVICES 10 hrs.

Organization of Ancillary Services: Lab Services – Department of Physiotherapy & Occupational Therapy –Organization of Blood Transfusion Services – Department of Radio – diagnosis.

UNIT IV MANAGEMENT OF DIETARY SERVICES 10 hrs.

Organization and management of Dietary Services – House-keeping and maintenance –Medical Records-Staffingthe hospital.

UNIT V RESOURCE MANAGEMENT 10 hrs.

Resource Mobilization - Management Assisted by Computers: Reservation, Admission, Registration & DischargeModule – Medical Record Index Module – Personnel Registration Module – Employee Registration Module – PatientCare Module – Human Resources Management Systems – Diet Planning – Pharmacy Module – Maintenance ofEquipments & Instruments.

TEXT BOOK:1. Dr. R. D. Lele,“Computers in Medicine”, McGraw Hill, 2005.

REFERENCE BOOKS:1. Dr. L.L. Rao, “Hospital Management”2. Bansal, “Computers in Management”







SBMX4007 THERAPEUTIC INSTRUMENTATION LABL T P Credits Total Marks

0 0 4 2 100

1. Surgical Diathermy Machine

2. Defibrillator

3. Study of Haemodialysis Machine

4. Ventilators

5. Study of Anesthesia Machine

6. Nebulizer

7. Pacemaker

8. Humidifiers

9. Shockwave Therapy

10. Cerebellar Stimulators

11. Physiotherapy equipment – Digi laser, Indsonic, Indotherm – 500W

SBMX4008 VIRTUAL INSTRUMENTATION LABL T P Credits Total Marks

0 0 4 2 100

1. Introduction to NI LabVIEW and Data Acquisition

2. Acquisition of Biopotentials using NI LabVIEW

3. Time domain and Frequency Domain Measurements on Biosignals.

4. Simulation of EEG using LabVIEW

5. Design of an Analog ECG Signal Generator using LabVIEW.

6. Design of a Biosignal Logger.

7. Design of a Heart Rate Analyzer.

8. Spectrum Analysis of ECG and PCG signals.

9. Extraction of Brainwaves from EEG.

10. Design of a Demand type Pacemaker using LabVIEW

11. * GPIB Communication using LabVIEW. [LabVIEW Basics 1 Manual]*

12. * VISA and Serial Communication using LabVIEW. * *[LabVIEW Basics 1 Manual]*

S24XPROJ PROJECT WORK AND VIVA VOCEL T P Credits Total Marks

0 0 30 15 100

The objective of the project work is to make use of the knowledge gained by the student at various stages ofthe degree course. Students, will also be permitted to undertake industrial/consultancy project Work, outside thedepartment, in industries/Research labs.

There shall be three assessments during the semester by a review committee. The student shall make threepresentations on the progress made before the committee at various stages of the Project work. The Head of theDepartment shall constitute the review committee for each branch of study. The total marks obtained in the threereviews, shall be taken in to account. There will be a viva-voce examination at the end of the Project work, conductedby one internal examiner and one external examiner. The total marks secured will be the sum of marks secured inthe Project reviews and Viva Voce Examination.

Each student is required to submit a Project report on the project assigned to him by the department. Thereport should be based on the information available in the literature or data obtained by the student by way ofexperiments conducted in the laboratory / industry.



SBMX1016 TELEMEDICINEL T P Credits Total Marks

3 0 0 3 100


Fundamentals of Telemedicine, Block diagram of Telemedicine, History of telemedicine: Main phases ofTelemedicine, Pre electronic Telemedicine, Electronic Telemedicine. Scope & Benefits and Limitation of Telemedicine.

UNIT II COMMUNICATION AND NETWORK 10 hrs.

Types of information: Audio, Video, Data, Fax, Still Image. Types of Communication and Networks: Overviewof PSTN, POTS, ISDN, ATM, Videoconferencing, Wireless Communication – RF, GSM Satellite and Microwave, CDPD.

UNIT III DATA EXCHANGE AND NETWORK SECURITY 10 hrs.

Basic concepts of internet, Network Configuration, Circuit and Packet Switching, H.320 series, T.120,h.324.Protocols: TCP/P, ISO – OSI, Standards for DICOM, Security: Encryption – DES, RSA, Cryptography.

UNIT IV ETHICAL AND LEGAL ASPECTS 10 hrs.

Confidentiality and law, Patient Right and consent, Access to medical Records, Consent treatment, jurisdictionalissues, Intellectual Property Rights.

UNIT V APPLICATIONS OF TELEMEDICINE 10 hrs.

Teleradiography – Basic parts of a Teleradiography System, Image acquisition and display system,Communication, Interpretation. Telepathology: Applications, Requirements, Security and Confidentiality tools,Telecytology: Applications, Telecardiology, Telehome – Care Home based Applications, Teleoncology: Applications,Telesurgery, Telepsychiatry, Teledermatology: Techniques.

TEXT BOOKS:

1. Olga (EDT), Ferrer – Roca, M. Sosa (EDT), Marcelo C, “Handbook of Telemedicine”, IOS press 1998.2. Ling Guan, “Multimedia image and video processing”, CRC Press, 2000

REFERENCE BOOKS:

1. Thorsten M Buzug, Heinz Handels, Dietrich Holz, “Telemedicine: Medicine and communication”, Springer Verlag 2001.2. Douglas V Goldstein, “E Healthcare: Harness the power of internet, e – commerce and e – care”, Jones and barlett Publishers.3. A. C Norris, “Essentials of Telemedicine and Telecare”, John Wiley & Sons 2002







SBMX1017 COMPUTERS IN MEDICINEL T P Credits Total Marks

3 0 0 3 100


Introduction – Historical review of development of computers and informatics – Use of internet in medicine –Online learning – Internet Vs Online services – computer based medical information retrieval – Prospectus of Medicalinformatics.

UNIT II HARDWARE AND NETWORKING 10 hrs.

Hardware – Microcontroller – Motherboard & its logic – RS232C and IEEE bus standards. PC based video,cards, modems and networking. System design – ECG, EMG, EEG data acquisition, storage and retrieval, transmissionof signals and images.

UNIT III MANAGEMENT INFORMATION SYSTEM 10 hrs.

Database Management – Data from patients, Coding and Classification, Computer based Patient Records, PatientCentered Information systems – Clinical departmental system, Nursing Information system.Decision support system –Artificial Intelligence – Need for expert system, Architecture and Computer based Medical diagnosis with example.

UNIT IV MONITORING AND MODELING 10 hrs.

Patient Monitoring – Physiological Monitoring, Information flow in clinical lab, Interfacing to HIS.Medical systemsmodeling – computer assisted drug discovery and development, Molecular modeling, pharmacophores. Radiotherapy– Role of PET and SPECT in drug discovery.

UNIT V HOSPITAL INFORMATION SYSTEM 10 hrs.

Protein database, Hospital Information System – Human Computer interaction in health care – Cost and benefitof information system - Patient database – security in medical information system.

TEXT BOOK:

1. R. D. Lee, “Computers in Medicine”, Tata McGraw – Hill, New Delhi, 1999.

REFERENCE BOOKS:

1. Mohan Bansal, “Medical Informatics” Tata McGraw Hill, 20022. Douglas V.Hall, “Microprocessors and Interfacing: Programming and hardware”, McGraw – Hill, Singapore, 1999.







SCSX1053ARTIFICIAL INTELLIGENCE AND EXPERT

SYSTEMSL T P Credits Total Marks

3 0 0 3 100

UNIT I AI & INTERNAL REPRESENTATION 10 hrs.

The AI problem – What is AI technology – Level of the Model – Criteria for Success problems, Problem Spaces& Searches & Heuristic Search Technology Problem as a State Space Search – Production Systems – ProductionSystem Characteristics – Generate & Test – Hill Climbing – Best First Search – Constraint Satisfaction – Means EndAnalysis.

UNIT II KNOWLEDGE REPRESENTATION 10 hrs.

Issues in Knowledge Representation – Using Predicate Logic – Representing Simple Facts in Logic, RepresentingInstance & Is a Relationship – Computable Functions & I Predicates – Representing Knowledge Using Rules: ProceduralVs. Declarative Knowledge – Forward Vs. Backward Reasoning.

UNIT III SLOT & FILLER STRUCTURES 10 hrs.

Weak Slot & Filler – Semantic Nets – Frames Strong & filler Structures – Scripts – CYC-CYCL

UNIT IV EXPERT SYSTEMS 10 hrs.

What are Expert Systems – Knowledge Representation in Expert Systems – Symbolic Computation – RuleBased Systems.

UNIT V TOOLS FOR BUILDING EXPERT SYSTEMS 10 hrs.

Using Domain Knowledge – Knowledge Acquisition – Design for Explanation – Black Board Architecture – TruthMaintenance Systems – Machine Learning – Case based Reasoning.

TEXT / REFERENCE BOOKS:1. Elaine Rich, Kevin Knight, “ Artifical Intelligence“ , 2nd Edition, Tata McGraw Hill, 1992.2. Peter Jackson, “Introduction to Expert Systems“, 3rd Edition, Addison Wesley, 1st Indian Reprint 2000







SCSX1054COMPUTER GRAPHICS AND VOLUME

VISUALIZATIONL T P Credits Total Marks

3 0 0 3 100

UNIT I OVERVIEW OF GRAPHICS SYSTEMS 10 hrs.

Video display devices – Raster scan systems – Random scan systems – Input devices- Hardcopy devices –Graphic software – Output primitives – Points and lines – Line drawing algorithms – Circle generating algorithms –Polygon filling algorithms.

UNIT II TWO DIMENSIONAL TRANSFORMATIONS 10 hrs.

Basic Transformations – Translation – Rotation – Scaling – Matrix Representation And Homogeneous Co –Ordinates – Composite Transformations – Two Dimensional Viewing – Viewing Pipeline – Windows To ViewportTransformations – Clipping Operations – Point Clipping – Line Clipping – Polygon Clipping.

UNIT III METHODS AND MODELS 10 hrs.

Visible Surface Detection Methods – Illumination Models – Halftone Patterns – Dithering Techniques – Polygon

Rendering Methods – Ray Tracing Methods – Color Models And Color Applications – Computer Animation

UNIT IV THREE DIMENSIONAL TRANSFORMATIONS 10 hrs.

Three dimensional object representations, Polygon surface – three dimensional transformations, three dimensionalviewing visible surface detection. Depth buffer. Scan line algorithms – BSP trees – octrees – Ray casting.

UNIT V VOLUME VISUALIZATION 10 hrs.

Visualization Pipeline – Reconstruction – 3d Voxel Image – Enhancement – Classification – Mapping – ViewingAnd Shading – Volumetric Shading Techniques – Introduction To Shading – Illumination Models – Light Sources –Basic Illumination Models – Surface Shading – Image Space Shading – Volume Representation – Viewing Algorithms– Marching Cube Algorithm.

TEXT / REFERENCE BOOKS:1. James D. Foley et.al., “ Introduction to Computer Graphics “, Addison Wesley Publishing Co., 1994.2. Donald Hearn, Pauline Baker, ” Computer Graphics“, 2nd Edition, Prentice Hall, 1994.3. Allan Watt, Mark watt, “ Introduction to Animation and Rendering “, Addison Wesley Publishing Co., 1994.4. Arie Kauffman, “ Volume Visualization “, IEEE Computer Society Press Tutorial, Washington, 1990.5. Donald Hearn, M. Pauline Baker, “ Computer Graphics “ , Prentice Hall of India Pvt. Ltd., 1993.6. Tay Vaughan, “ Multimedia“, 5th Edition, Tata McGraw Hill, 2000.







SCSX1007JAVA PROGRAMMING

(Common to CSE, IT, E&C, BIOINFO & BIOMED)


3 0 0 3 100


Classes and Objects – Class Fundamentals – Declaring Objects – Methods – Constructors – Garbage Collection- Inheritance – Basics – Using Super – Method Overriding – Abstract Classes – Using final with inheritance - StringHandling – String class – String buffer class.

UNIT II PACKAGES AND INTERFACES 10 hrs.

Using Packages – Importing packages – Access protection – Interfaces – Exception Handling & I/O Streams –Exception Types – Using try, catch, throw, throws and finally – Byte and Character Streams – Multithreading –JavaThreadModel – Main thread – Creating muliple thread – Thread priorities – Synchronization.

UNIT III APPLET PROGRAMMING 10 hrs.

Java.lang package – Simple type wrappers – Runtime – System – Object – Class – Math thread – Usingclone() and the Cloneable Interface – Applet Class – Applet basics – Applet architecture – HTML APPLET tag –Passing parameters to applets.

UNIT IV EVENT HANDLING 10 hrs.

Delegation Event Model – Handling Mouse and Keyboard Events – Adapter Classes – AWT – AWT Classes– Window Fundamentals – Graphics, Fonts – AWT Controls – Layout Managers – Menus – Dialog Boxes.

UNIT V NETWORKING 10 hrs.

Basics – Inet address – TCP/ IP – URL – UDP - Java beans and swings – Bean concepts - Events in beanbox – Developing a simple Bean using BDK – Swing components.

TEXT / REFERENCE BOOKS:1. Herbert Schildt, ”The Complete Reference JAVA2”, 5th Edition, Tata McgrawHill, 2006.2. Bruce Eckel, ”Thinking in Java”, Pearson Education, 2000.3. Clayton Walnum, ”Java By Example”, QUE Publications, 2000.4. Subrahmanyam Allamaraju and Cedric Buest, “Professional Java Server Programming”, J2EE 1.3 Edition, APress, 2007.


Max. Marks : 80 Exam Duration : 3 Hrs.





SECX1069 NANO ELECTRONICSL T P Credits Total Marks

3 0 0 3 100

UNIT I INTRODUCTION TO NANOSTRUCTURES 10 hrs.

Electronic states in crystal energy bands, Concepts of 2D nanostructures (quantum wells), 1D nanostructures(quantum wires) OD nanostructures (quantum dots), artificial atomic clusters.

UNIT II CHARACTERIZATION OF NANOPARTICLES 10 hrs.

Size dependent properties, Size dependent absorption spectra, Blue shift with smaller sizes, Phonons innanostructures, Contacts at Nano level, AFM, lSTM tip on a surface.

UNIT III FUNDAMENTAL CHARACTERS OF QUANTUM DOTS 10 hrs.

Charging of quantum dots, Coulomb blockade, Quantum mechanical treatment of quantum wells, wires and dots,Widening of band gap in quantum dots, Strong and weak confinement, Properties of coupled quantum dots, Opticalscattering from Nano defects.

UNIT IV NANOCOMPOSITES 10 hrs.

Nanocomposites Electronic and atomic structure of aggregates - nanoparticles Theory - modeling of nanoparticlesfictionalization processes.

UNIT V SYNTHESIS OF NANOPARTICLES 10 hrs.

Synthesis and characterization methods of Synthesis: Molecular beam epitaxy, MOCVD, chemical routes,nanoparticles on polymers, pulsed laser deposition, ion beam assisted techniques including embedded nanoparticles,RF sputtering.

TEXT BOOK:1. Nanoelectronics and Nanosystems , Karl Goser, Peter Glosekotter, Jan Dienstuhl., Springer, 2004

REFERENCE BOOKS:1. K.Bamam and D.Vvedensky Low Dimensional Semiconductor Structures, (Cambrige University Book) 20012. L.Banyai and S.W.Koch Semiconductor Quantum Dots, (World Scientific) 19933. J.H. Davies, An introduction to the physics-a low dimensional semiconductors, Cambridge Press, 1998.4. Karl Goser, Peter Glosekotter, Jan Dienstuhl., Nanoelectronics and Nanosystems, Springer, 2004







SICX1016FUNDAMENTALS OF MECHATRONICS

(Common to EIE, E&C, ECE, EEE, ETCE & BIOMED)


3 0 0 3 100


Mechatronics: Definition & Key Issues – Evolution – Elements – Mechatronics Approach to Modern EngineeringDesign.

UNIT II SENSORS AND TRANSDUCERS 10 hrs.

Types – Displacement, Position and Proximity & Velocity Sensors – Signal Processing – Data Display.

UNIT III ACTUATION SYSTEMS 10 hrs.

Introduction to Mechanical Types and Electrical Types – Pneumatic & Hydraulic Systems – Applications –Selection of Actuators

UNIT IV CONTROL SYSTEMS 10 hrs.

Types of Controllers – Microprocessor Applications in Mechatronics- 2 case studies in automobiles, and 2 casestudies in robotics, – Programming Interfacing – Computer Applications

UNIT V RECENT ADVANCES 10 hrs.

Manufacturing Mechatronics – Automobile Mechatronics -2 Case Studies – Medical Mechatronics – 2 Case Studies

TEXT BOOKS: 1. W.Bolton. N, “Mechatronics: Electronic Control System for Mechanical & Electrical Engineering”, 2nd Edition, Pearson Education,

2004. 2. Dr. K.P. Ramachandran, G.K. Vijaya Raghavan, Mechatronics, 2nd Edition, A.R.S. Publications, 2008.

REFERENCE BOOKS: 1. D.A. Bradly, D. Dawson, N.C.Burd and A.J. Loader, “Mechatronics: Electronics in Products and Processes” Nelson Publisher, 2004. 2. Michael B.Histand & David G.Alciators, “Introduction to Mechatronics & Measurement systems”, McGraw- Hill International Editions,

1998. 3. Dan Necsulescu, “Mechatronics”, Pearson Education, 2005.


Max.Marks : 80 Exam Duration : 3 hrs.





SECX1070 PIC AND EMBEDDED SYSTEMSL T P Credits Total Marks

3 0 0 3 100

UNIT I REVIEW OF EMBEDDED HARDWARE 10 hrs.

Terminology, Gates, Timing Diagram, Microprocessors, Buses - Direct Memory Access- Interrupts- Other commonparts- Built-ins on the Microprocessor- Conventions used on Schematics -Interrupts. Microprocessor Architecture –Interrupts basics- Shared-Data problem- Interrupt latency. Examples of Embedded System.

UNIT II MICROCHIP PIC MICRO CONTROLLER 10 hrs.

Introduction, CPU Architecture- Registers- Instruction sets addressing modes- Loop timing- Timers- Interrupts,Interrupt timing, I/O Expansion, I2C Bus Operation Serial EEPROM, Analog to Digital converter, UART-Baud Rate-DataHandling-Initialization, Special Features – Serial Programming-Parallel Slave Port.

UNIT III SOFTWARE DEVELOPMENT 10 hrs.

Round – Robin, Round robin with Interrupts, function-Queue-Scheduling Architecture, Algorithms. Introduction to- Assembler- Compiler - Cross Compilers and Integrated Development Environment (IDE). Object Oriented Interfacing,Recursion, Debugging strategies, Simulators.

UNIT IV REAL TIME OPERATING SYSTEMS 10 hrs.

Task and Task States, Tasks and data, Semaphores and shared Data Operating system Services-Messagequeues -Timer function – Events - Memory Management, Interrupt Routines in an RTOS environment, Basic designusing RTOS.

UNIT V BUS PROTOCOLS AND APPLICATION 10 hrs.

I2C bus and CAN bus; Internet-Enabled Systems, Design Example-Elevator Controller. Application of embeddedsystem in biomedical engineering.

TEXT BOOKS:1. David E Simon, “An Embedded Software Primer”, Pearson Education Asia, 2001.2. Wayne Wolf, Computers as Components, 2nd Edition, Morgan Kaufmann Publisher, 2008

REFERENCE BOOKS:1. John B Pitman, “Design with PIC Micro controllers”, Pearson Education Asia, 1998.2. Burns, Alan and Wellings, Andy, “Real-Time Systems and Programming Languages”, 3rd Edition, Addision Wesley Longman, 20013. Jane.W.S. Liu, “Real-Time systems”, Pearson Education Asia, 20004. C. M. Krishna and K. G. Shin , “Real-Time Systems”, Mc. Graw Hill, 19975. Jonartthan W. Valvano, “Embedded Micro computer Systems, Real time Interfacing”, Thomson learning 2001.







SBMX1015 BIOMEMS AND NANOTECHNOLOGYL T P Credits Total Marks

3 0 0 3 100


MEMS – definition. Origin of MEMS – Types – Materials used and their properties. MEMS Technology.Applications in health care. Integrated MEMS and microsystem.

UNIT II PROCESSING: MICRO MACHINING TECHNOLOGY 10 hrs.

Lithography- etching- Ion implantation- wafer bonding- Integrated processing- Bulk micro machining- surface micromachining- coating technology and CVD-LIGA process.

UNIT III MICROSYSTEMS AND MICROFLUIDS 10 hrs.

General principles- Microsensors – Actuators- Electrostatic forces- Piezoelectric crystals – Intelligent materialsand structures. Fundamentals of micro fluids, lab – on – a chip devices - Silicon and glass micromachining for micrototal analysis systems.Surface chemistry in polymer microfluidic systems.

UNIT IV APPLICATION IN MEDICINE 10 hrs.

Trends in MEMS for health care. Drug delivery systems - Biochip – Micro needles- Microelectrodes- Neuralprosthesis – shape memory implants.

UNIT V BIOMEDICAL NANOTECHNOLOGY 10 hrs.

Nanotechnology- Medical applications of Nanotechnology- Drug synthesis and delivery- Nanofabrication methods– Nanomaterials in human body- Toxicity in nanomaterials.

TEXT BOOKS:1. Tai-Ran Hsu, “MEMS & Microsystem, Design and manufacture”, McGraw Hill, 2007.2. Malsch, NeelinaH., ed., “Biomedical Nanotechnology”, Washington, DC: CRC Press, 2005

REFERENCE BOOKS:1. Marc J. Madou, “Fundamentals of Microfabrication and Nanotechnology”, 3rd Edition, Three-Volume Set,CRC Press2. Mohamed Gad-el-Hak, “The MEMS Handbook” CRC Press, 20053. L’HocineYahia, “Shape Memory Implants”, Springer, 2000.







SBMX1026HARDWARE DESCRIPTION LANGUAGE

(VHDL / VERILOG)L T P Credits Total Marks

3 0 0 3 100

UNIT I INTRODUCTION TO VHDL 10 hrs.Digital system design process- hardware Simulation- Levels of abstraction- Language elements of VHDL Data

objects – Data types – Operators – Variable assignment. Operators Objects in Classes- Signal Assignments- Inertialdelay mechanism-Transport delay mechanism- Concurrent and sequential assignments- Delta delay.

UNIT II STYLES OF MODELING IN VHDL 10 hrs.Process statement: Declarative part, statement part, sensitivity list, syntax details of process statements, Assertion

Statement, sequential wait statement, behavioral- Dataflow modeling- Structural Modeling- Examples- Componentdeclaration- Component instantiation.

UNIT III ADVANCED FEATURES AND SUBPROGRAM 10 hrs.Genetic- Configurations- Specifications- Declaration- Generate Statements- Guarded signals- Model simulation-

Test Bench- Examples, Subprograms, Subprogram Overloading- Operator Overloading.

UNIT IV PACKAGES, LIBRARIES 10 hrs.Package Declaration- Package body- Design Libraries- Modeling Synchronous logic- State machine modeling-

Moore FSM - Melai FSM.

UNIT V INTRODUCTION TO VERILOG HDL 10 hrs.Introduction to system verilog - Language Elements - Identifiers, Compiler Directives, Value set, data types,

Operands, Operators, Arrays, operators & Expressions - procedural & control flow statements, Behavioral – Data Flow-Structural Modeling.

TEXT BOOK:1. J. Bhaskar, A VHDL primer, 3rd Edition, Pearson Education, 1999.

REFERENCE BOOKS:1. Zainalabedin Navabi, VHDL- Analysis and modeling of digital systems, 2nd Edition, MGH, 1998.2. Peter G. Ashenden, Morgan Kauffman, The Student’s guide to VHDL, 2009.3. Charles H. Roth, Jr, Digital Systems Design using VHDL, Thomson Learning, 2006.4. Stphen Brown "Fundamental of Digital logic with VHDL Design", Tata McGraw Hill, 2008.5. Douglas L. Perry "VHDL", McGraw Hill, 2002.6. J. Bhaskar, A Verilog HDL Primer, 2nd Edition, BS Publications, 2007.







SBTX1027 TISSUE AND STEM CELL ENGINEERINGL T P Credits Total Marks

3 0 0 3 100


Introduction to Tissue Engineering – Structure and organization of tissues – Transport properties of tissues –Mass transfer – Diffusion and reaction of proteins

UNIT II GENERAL ASPECTS OF CELLS 10 hrs.

General aspects of cells in culture – Cell matrix - Cell migration and control – differential cell adhesion andtissue organization – Hormone & Growth factor signaling – Scaffolds & tissue engineering - Angiogenesis.

UNIT III APPLICATION OF STEM CELLS 10 hrs.

Origin, characterization, potential applications of human stem cells - Protocols for isolation and identification ofstem cells – Differentiation of cells from human, neurospheres into neurons, astrocytes and oligodendrocytes –Immunolabelling

UNIT IV GENE THERAPY 10 hrs.

Gene therapy – immunorejection in stem cell therapy – new therapy for autoimmune disease – prenatal diagnosisof genetic abnormalities using fetal CD34+ stem cells

UNIT V REPLACEMENT THERAPY 10 hrs.

Stem cells in treatment for major diseases – cell replacement therapy – germ line therapy

TEXT BOOK:1. Sameul E Lynch, De Robertis, J Geng, Tissue Engineering, 3rd Edition, Elsevier, 2007

REFERENCE BOOKS:1. Robat Lanza and Robert Langer, “Principles of Tissue Engineering”, Elsevieer, 2007.3. John RW Master, Animal Cell Culture – A Practical Approach Oxford University Press, 2004.4. Bernhard Palsson, Jeffery A Hubble, Robert R Lonsey, Tissue Engineering, CRC Press, 2003.5. Kursad and Purksen Embryonic Stemcell, Humana Press, 2002.







SBTX1028 GENETIC ENGINEERING AND ITS APPLICATIONSL T P Credits Total Marks

3 0 0 3 100

UNIT I EXPRESSION AND DETECTION OF CLONES 10 hrs.

Detection of clones and its expression – expression of cloned genes in yeast and E. coil – Blot analysis –Southern, Northern and Western Blot – Genomic and cDNA library construction and its applications.

UNIT- II PCR AND ITS APPLICATIONS 10 hrs.

Principles – designing of primers – PCR methodology – Types of PCR – Identification of PCR products -application in disease profile

UNIT III MOLECULAR MARKERS 10 hrs.

Molecular markers – RFLP – RAPD – AFLP – 16s rRNA typing gene chip and micro array; application indisease profile

UNIT IV APPLICATIONS OF rDNA TECHNOLOGY 10 hrs.

Gene cloning in medicine, transgenic animals. Gene therapy, types of gene therapy methodology advantagesand limitations of gene therapy and its applications

UNIT V OTHER APPLICATION 10 hrs.

Site – directed mutagenesis, methods of gene transfer, plant agrobacterium mediated using gene gun, animalsembryo transfer example dolly. Application of recombinant technology in medicine.

TEXT BOOK: 1. Old RW, Primrose SB, Principle of Gene Manipulation: An Introduction to Genetic Engineering, Black Well Scientific Publications,

1993

REFERENCES:1. T. A. Brown, Gene Cloning, 5th Edition, Blackwell Publishing 2006.2. Ansubel FM., A, Kingston AE, Moore DO, Current protocols in Molecular Biology, Greene Publishing Associates, NY, 1988.3. Berger SL, Kimmer AR, Methods in Enzymology, Vol 152, Academic press, 1987.4. Gerald Karp, Cell and Molecular Biology, 6th Edition, John Wiley & Sons., 2009







SBTX1021 NEUROSCIENCEL T P Credits Total Marks

3 0 0 3 100

UNIT I INTRODUCTION TO NEUROSCIENCE 10 hrs.

History of neuroscience, Applications of neuroscience, neural engineering, Contemporary neuroscience.

UNIT II INTRODUCTION TO NERVOUS SYSTEM 10 hrs.

Nervous system: central nervous system, peripheral nervous system, autonomic nervous system; anatomicalorganization of the nervous system, functional organization of the nervous system, neurons-the nerve cell, neuronsmaking us claim humans (vision, hearing, taste, touch, smell, cognition).

UNIT III ELECTRICAL PROPERTIES OF NERVOUS SYSTEM 10 hrs.

Electrolytes within our neurons; Ion channels, Local signaling, Signal propagation - Action potential, Synapse,Synaptic integration, Modulation of synaptic transmission, Nerve-Muscle interaction, Applied neuroscience.

UNIT IV NEURAL NETWORKS 10 hrs.

Current flow in neurons, Introduction to electro diagnostic signals and their measurement, nerve conduction study,evoked potentials.

UNIT V DISORDERS 10 hrs.

Neuroscience methods and techniques to understand the functions of nervous system – Pathology of Nervoussystem – Molecular and cellular mechanisms of Parkinson’s, Huntington’s and Alzheimer’s diseases.

TEXT BOOKS:1. Richard S Snell, “Clinical Neuro Anaktomy”, 6th Edition., Lippencott Williams & Wikkins, 2006.2. Ganong W.F. “Review of Medical Physiology”, 21st Edition, McGraw Hill, 2003.

REFERENCE BOOKS:1. Eric Kandel, Principles of Neural Science, Elsevier, 2000.2. U.K.Misra, Clinical neurophysiology, Elsevier Health Science, 2006.







SBMX1023 PHARMACOLOGY AND TOXICOLOGYL T P Credits Total Marks

3 0 0 3 100

UNIT I INTRODUCTION 10 hrs.Preclinical studies, Clinical trials, Regulatory aspects in drug development, Role of FDA, Important amendments

in drugs regulation. Indian drugs and cosmetic act.

UNIT II PHARMACEUTICS 10 hrs.A fundamental introduction to solid, semisolid and liquid dosage forms, including powders, true solutions, colloids,

suspensions and emulsions.

UNIT III PHARMACOLOGY 10 hrs.Analgesic, antipyretic and anti-inflammatory agents, drug in rheumatoid arthritis and gout, drug in bronchial asthma,

drug in allergic disorders. Chemical and biological aspects of certain drugs, respiratory drugs, diuretics & prostaglandin’s.

UNIT IV INDUSTRIAL PHARMACEUTICS 10 hrs.Tablets-wet granulation – dry granulation or slugging –coating of tablets. Capsules Sustained action dosage

forms-parental solutions-oral liquids – injections-ointments-topical Applications-ointments Preservation – PackingTechniques.

UNIT V TOXICOLOGY 10 hrs.Environmental toxicants-classification - occurrence-sources-effects on plants. Heavy metal toxicity – lead and

Chromium bioaccumulation. Atmospheric toxicants - Carbon monoxide, Sulphur oxide. Pollution indicators definition ofindicator plants, algae. Toxins of biological origin - botulins, afflotoxins.

TEXT BOOKS:1. Tripathi, “General Pharmacology”, 5th Edition, Jaypee Brothers, 2003.

REFERENCE BOOKS:1. “Howland et Al” Lippincott’s Illustrated Reviews, “Pharmacology”, ISBN Number:0-7817-4118-1, 3rd Edition, 20062. Duffous J.H, “Environmental Toxicology”, Edward Arnold Publiacation, London, 1980.3. Sharma P.D, “Environmental Biological and Toxicology”, Rastogi & co, Meerat, 1993.4. Leon Lachmanetal, “Theory and practice of Industrial Pharmacy”, Lea and Feiger, 1986.


Max. Marks: 80 Exam Duration: 3 hrs.PART A : 2 Questions from each unit, each carrying 2 marks 20 marksPART B : 2 Questions from each unit with internal choice, each carrying 12 marks 60 marks



SBMX1024 FORENSIC SCIENCEL T P Credits Total Marks

3 0 0 3 100


Cell and its inclusions – structure and function – types of cells: Blood & Body fluids – forensic significance –morphological identification of bones – forensic importance.

UNIT II IDENTIFICATION OF HUMAN REMAINS 10 hrs.

Identification of Human remains – methods of reconstruction – personal identity in the living and the dead –DNA fingerprinting – Blotting types (Southern, Northern, Western) – post mortem examination – poisoning – medicolegal aspects.

UNIT III FINGER PRINTS 10 hrs.

Finger Prints – importance of plastic and visible finger prints – transfer methods of finger prints – fingerprintpatterns – their classification – ridge characteristics – foot prints – importance – gait patterns and their characteristics– photography of foot prints – sunken and surface foot prints.

UNIT IV INTRODUCTION TO EXAMINATION OF HANDWRITING 10 hrs.

Introduction to examination of Handwriting – development of handwriting science – handwriting experts – expertwitness in courts – relationship between investigating officers and handwriting experts – relevant sections of IndianPenal Code – criminal procedure code and evidence act

UNIT V SEROLOGY 10 hrs.

Serology – basic principles of serology – concept of antigen and antibody and their reaction – application ofserology in forensic science. Karyotyping – banding patterns - chromosomal abnormalities – sex determination – sexlinked inheritance.

TEXT BOOKS:

1. De Robertis, “General Cytology”, 6th Edition, Saunders, 20082. E J Gardner, “Principles of Genetics”, 7th Edition, McGraw Hill, 2001

REFERENCE BOOKS:

1. M. Krawczak and J. Schmidtke, “DNA Finger printing”, BIOS Scientific Publisher, 1995.2. Richard Saferstein Ed, “Forensic Science Hand Book” Prentice Hall, 2010.3. P L Carpenter,“Immunology and Serology”, W B Saunders Company, 1965.4. David Friedfielder,“Molecular Biology”, 4th Edition, Narosa publications, 1995.







SBMX1020 MEDICAL WASTE MANAGEMENTL T P Credits Total Marks

3 0 0 3 100


General Introduction, Definition of Biomedical Waste, General and Hazardous health care waste – Colour Codingand types of containers for disposal of medical waste, Segregation, Collection & Disposal,

UNIT II BIOMEDICAL WASTES 10 hrs.

Infectious waste, Genotoxic waste, Waste Sharps – Categories, Categorization and composition of Biomedicalwaste. Liquid Biomedical Waste - Radioactive wastes, Metals, Chemicals & drugs

UNIT III BLOOD PRODUCTS 10 hrs.

Human Blood and Blood Products, pathological wastes, Contaminated sharps, Contaminated animal carcasses,body parts, and bedding Basic information about infection, Infectious agents on organizations spread of infection, Basicinformation about Hospital acquired infection.

UNIT IV STERILISATION 10 hrs.

Disinfections unit container for Autoclaving, Sharp waste containers for storage & transportation, autoclaving,Incineration, Plasma Pyrolysis /Gasification systems, Composting.

UNIT V MODERN TECHNOLOGY FOR MEDICAL WASTES 10 hrs.

Modern Technology for handling Biomedical Wastes – Monitoring & Controlling of Cross Infections, ProtectiveDevices – Bioethics and Handling of Waste Management.

TEXT BOOK:1. V. J. Landrum, Medical Waste Management and disposal, Elsevier, 1991

REFERENCE BOOKS:1. Malhotra A., Hospital Management : An Evaluation, Global India Publications, 2009.2. S L Goel, “Hospital Management”, Deep and Deep Publications, 2010.3. J Glyn Hendry & Gary W Heinke, “Environmental Science and Engineering”, Prentice Hall India, 20044. Shyam Divan, “Environmental law and policy in India”, Oxford India Press, 2004.5. Charles A Wentz, “Hazardous Waste Management”, McGraw Hill Inc, Newyork, 1995







SBMX1018 ADVANCES IN CARDIAC SIGNAL PROCESSINGL T P Credits Total Marks

3 0 0 3 100


Bipolar of heart – S.A. Node – Depolarization - Bipolar – unipolar. Arrhythmias – atrial, junctional, ventricular,Atrioventricular blocks, Bundle Branch and Fascicular Blocks Myocardial Ischemia, Injury and Infarction.

UNIT II CARDIO SIGNAL VARIABILITY 10 hrs.

Data Acquisition and Preprocessing - Modeling Techniques – Arrhythmia Detection ,HRV and Blood Pressure,HRV and Nervous System, HRV and Diabetes, HRV and Respiration, HRV and Drugs, HRV and Smoking, HRV andAlcohol.

UNIT III DATA FUNCTION OF CARDIO VASCULAR SIGNAL 10 hrs.

Approaches for Fusion, Rule Based Approach, Fuzzy Based Decision Making, Fuzzy Logic Approach, Patientstates Diagnosis System Implementing Data Fusion.

UNIT IV CLASSIFICATION 10 hrs.

Neural Network Classifier, Inputs to the classifier, Surrogate Data, Fuzzy Classifier, Neuro-Fuzzy Classifier.

UNIT V STORAGE AND TRANSMISSION OF CARDIAC DATA 10 hrs.

Concept of Interleaving, The Interleaving Process – Encryption of the Text File – Encryption of the Graphic File– Interleaving in DFT Domain – Interleaving in DCT – Interleaving in Wavelet Domain – Evaluation and CorrectingCodes.

TEXT BOOK:1. U.R Acharya, J.S. Suri, J.A.E Spaan, S.M. Krishnan, “Advances in cardiac Signal Processing” Springer, 2007.

REFERENCE BOOKS:1. Stergios Stergiopoulos, “Advanced Signal Processing”, CRS press, 20092. Yukihiko Nose, “Cardiac Engineering”, Wiley – Interscience, New York and London, 1970







SBMX1019 ELECTROPHYSIOLOGYL T P Credits Total Marks

3 0 0 3 100

UNIT I FUNDAMENTALS OF ELECTROPHYSIOLOGY 10 hrs.

Introduction of electrophysiology, Cell membrane and membrane potentials, Muscles, muscles spindles andelectrical conductivity in the myocytes

UNIT II FUNDAMENTALS OF NEUROPHYSIOLOGY 10 hrs.

Introduction of neurophysiology, Nerves and neurons, Physiology of nerve conduction, Electrical activity of brain,Evoked potentials.

UNIT III ELECTROPHYSIOLOGICAL TECHNIQUES 10 hrs.

Introduction of ECG, EMG and EEG, ECG and its clinical applications, EMG and its clinical applications, EEGand its clinical applications.

UNIT IV EVOKED POTENTIALS 10 hrs.

Introduction of evoked potentials, NCV studies and its clinical applications, SEP and its clinical application, MEPand its clinical application

UNIT V RECENT TRENDS AND INSTRUMENTS FOR THERAPY 10 hrs.

Surgical diathermy – Electro anesthetic and surgical techniques – Sources of Electric hazards and safetytechniques – Computer Aided Tomography, PET and SPECT – CT scan – MRI – Endoscopy

TEXT BOOKS:1. Raymond Cooper, Colin Binnie and Richard Billings, “Techniques in Clinical Neurophysiology”, Elsevier Publishers, 2005.2. Gerard J.Tortora and Bryan Derrickson, “Principles of Anatomy and Physiology”, 12th Edition, Wiley, 2008.3. U.K.Mishra and J.Kalita, “Clinical Neurophysiology”, B.I. Churchill Livingstone, 2003.

REFERENCE BOOKS:1. U.Windhorst and H.Johansson, “Modern Techniques in Neuroscience Research”, Springer, 19992. Leif Sornmo and Pablo Laguna, “Bioelectrical signal Processing in Cardiac and Neurological Applications”, Elsevier Academic Press,

2005.3. R. S. Khandpur, “Hand Book of Biomedical Instrumentation”, Tata McGraw Hill, 2008.







SBMX1022 BIOPHOTONICSL T P Credits Total Marks

3 0 0 3 100


Optical properties of tissues: fundamental optical properties – refraction, scattering, absorption – light transportin tissue – preliminaries to radiation transport – time resolved propagation of light pulses – tissue properties – refractiveindices, scattering and absorption properties.

UNIT II OPTOTHERMAL INTERACTIION 10 hrs.

Light tissue interactions – light interactions with a strongly Scattering tissue – continuous wave light, short lightpulses, diffused photon density waves. Temperature rise and tissue damage – optothermal and optoacousticeffects.Fluorescence, Speckle effects.

UNIT III INSTRUMENTATION IN PHOTONICS 10 hrs. Instrumentation for absorption, scattering and emission measurement, excitation light sources – high pressure

arc lamp, solid state LEDs, LASERs, optical filters, polarisers, solid state detectors, time resolved and phase resolveddetectors.

UNIT IV BIOPHOTONIC DIAGNOSTICS 10 hrs.Near IR spectroscopy for biological glucose analysis, flow cytometry – basic operation, optical response –

applications – optical biosensors – principles, biorecognition, optical transduction – Bioimaging – cellular, tissue imagingand in vivo imaging. Introduction to Optical Coherence Tomography.

UNIT V BIOPHOTONIC THERAPY 10 hrs.

Photodynamic therapy – basic principle, photosensitizers, mechanism of photodynamic action, applications – Lasertissue welding, lasers in dermatology, neurosurgery, ophthalmology, urology.

TEXT BOOKS:1. William T Silfwast, “Laser fundamentals”, Cambridge University Press, 1998.2. Ed., Tuan Volume Dinh, “Biomedical Photonics Handbook”, CRC Press, 2003.3. Paras N Prasad, “Introduction to Biomedical Photonics”, John Wiley. 2003

REFERENCE BOOKS:1. Leon Goldman, “The Biomedical Laser Technology and Clinical Applications”, Springer Verlag, 1981.2. Leon Goldman and R. James Rockwell, “Lasers in Medicine”, Gordan & Breach, Science Publishers Inc, 19713. Koebmer K R, "Lasers in Medicine", John Wiley & Sons, 1980







SBMX1025 MODELLING OF PHYSIOLOGICAL SYSTEML T P Credits Total Marks

3 0 0 3 100

UNIT I APPROACHES TO MODELING 10 hrs.

The technique of mathematical modeling, classification of models, characteristics of models. Purpose ofphysiological modeling and signal analysis, linearization of nonlinear models. Time invariant and time varying systemsfor physiological modeling.

UNIT II NONPARAMETRIC MODELING 10 hrs.

Volterra models. Wiener models. Efficient volterra kernel estimation Analysis of estimation errors. Parametricmodeling: Basic parametric model forms and Estimation procedures. Volterra kernels of nonlinear differential equations.Discrete-time volterra kernels of NARMAX models. From Volterra kernel measurements to Parametric models.Equivalence between continuous and Discrete -parametric models.

UNIT III EQUIVALENT CIRCUIT MODEL 10 hrs.

Electromotive, resistive and capacitive properties of cell membrane, change in membrane potential with distance,voltage clamp experiment and Hodgkin and Huxley’s model of action potential, the voltage dependent membraneconstant and simulation of the model, model for strength-duration curve, model of the whole neuron. Huxley modelof isotonic muscle contraction, modeling of EMG, motor unit firing: amplitude measurement, motor unit & frequencyanalysis.

UNIT IV PHYSIOLOGICAL MODELING 10 hrs.

Electrical analog of blood vessels, model of systematic blood flow, model of coronary circulation, transfer ofsolutes between physiological compartments by fluid flow, counter current model of urine formation, model of Henle’sloop, and Linearized model of the immune response: Germ, Plasma cell, Antibody, system equation and stabilitycriteria.

UNIT V SYSTEM MODELING 10 hrs.

Electrical circuit model of oxygenation. A model of immune response to disease (Block Diagram). Modeling ofmulti input/multi output systems: The Two-input case. Applications of Two-input modeling to physiological systems. TheMulti input case spatiotemporal and spectro temporal modeling.

TEXT BOOK:1. Michel C Khoo, “Physiological Control Systems - Analysis, simulation and estimation”, Prentice Hall of India, 2001.

REFERENCE BOOKS:1. David T. Westwick, Robert E. Kearney, “Identification of Nonlinear Physiological Systems”, Wiley-IEEE Press, 2003.2. Endele, Blanchard &Bronzino, “Introduction to Biomedical Engineering”, Academic press, 2005.3. Suresh. R. Devasahayam, “Signals & Systems in Biomedical Engineering”, Kluwer Academic, Plenum Publishers, 2000.4. V.Z. Marmarelis, “Advanced methods of physiological modeling”, Springer, 1994.5. J. Candy, “Signal Processing - The Model Based approach”, John Wiley Publications, 20066. Lawrence Stark, “Neurological Control System”, Plenum Press, 1995.7. R.B. Stein, “Nerve and Muscle”, Plenum Press, 1980.







SICX1020THEORY OF ROBOTICS AND AUTOMATION

(Common to EIE, E&C, ECE, ETCE, EEE, BIOMED)


3 0 0 3 100

UNIT I BASIC CONCEPTS 10 hrs.

Origin & various generation of Robots - Robot definition - Robotics system components – Robot classification- Coordinate frames - Asimov’s laws of robotics – degree of freedom – work volume - Need for Automation - typesof automation – fixed, programmable and flexible automation.

UNIT II SENSORS AND VISION SYSTEM 10 hrs.

Sensing - Range, proximity, position, velocity, acceleration, Touch, Force, Torque. Optical & laser sensors.Machine vision - Introduction, Image acquisition, Illumination Techniques, Image conversion, Cameras, Image processingand analysis – image data reduction – segmentation feature extraction – Object recognition.

UNIT III GRIPPERS AND ROBOT DYNAMICS 10 hrs.

Introduction - various types of grippers-design considerations. Construction of Manipulator – Introduction to RobotDynamics – Lagrange formulation – Newton Euler formulation – Properties of robot dynamic equations.

UNIT IV KINEMATICS AND PATH PLANNING 10 hrs.

Forward Kinematics – Denavit Hartenberg Representation. Inverse Kinematics – Geometric approach.

UNIT V PROGRAMMING LANGUAGES AND APPLICATIONS 10 hrs.

Robot programming - Fixed instruction, sequence control, General programming language, Specific programminglanguages. Robots for welding, painting and assembly – Remote Controlled robots – Robots for nuclear, thermal andchemical plants.

TEXT BOOKS:

1. Mikell P. Groover ,Weiss G.M. Nagel R.N. Odraj . N.G. , “Industrial Robotics”, 3rd Reprint Edition, Tata McGraw Hill, 2008.2. Deb.S.R. “Robotics Technology and flexible Automation”, 9th Reprint Edition, Tata Mc Graw Hill, 2004.3. K.S Fu, R C.Gonzalez, CSG Lee- “Robotics”, McGraw Hill, 2008.

REFERENCE BOOKS:

1. John J Craig “Introduction to Robotics Mechanics & control, Low price Edition, 7th Reprint, Pearson Education, 2005.2. Bijoy K Ghosh, “Control in Robotics and Automation : Sensor Based Integration”, Academic Press, 1999


Max.Marks : 80 Exam Duration : 3 hrs.





SBMX1021 RESEARCH METHODOLOGY AND MEDICAL ETHICSL T P Credits Total Marks

3 0 0 3 100


Centrifugation and Calorimeter - Centrifugation: Principle and Types of centrifuges. Ultracentrifugation, densitygradient centrifugation and continuous centrifugation. Calorimeter - Principle, Types and its applications

UNIT II ELECTROPHORESIS 10 hrs.PAGE &

Principle of Gel electrophoresis, Polyacrylamide gel electrophoresis (PAGE & SDS PAGE) and Agarose gelelectrophoresis, comet assay and capillary electrophoresis. Two dimensional electrophoresis and isoelectrofocussing.Radioisotopes and their applications in biology - GM and Scintillation counter.

UNIT III MOLECULAR BIOLOGICAL TECHNIQUES 10 hrs.

Isolation and amplification of nucleic acid-Genome DNA (E.coli), Plasmid DNA, total RNA, Polymerase chainreaction. Southern blot-western blot-Northern blot-DNA finger printing and Microarray

UNIT IV BIOSTATISTICS 10 hrs.

Measures of Central Tendency: Arithmetic Mean, Median, Mode. Measures of Dispersion: Range, varianceand standard deviation. Correlation and Regression: Correlation coefficient Regression equation. Biological significanceof correlation and regression - Tests of significance: Basis of statistical inference - Student’s ’T’ test for mean, differenceof means and test for correlation and regression coefficients - Chi-square test - Analysis of variance.

UNIT V MEDICAL ETHICS 10 hrs.

Introduction to medical ethics, Ethical theory, the relation between medical workers and patients, Beneficenceand autonomy, Competence, Confidentiality. Hastening death, Active and passive euthanasia, the definition of death,the law - involuntary euthanasia.

TEXT BOOKS:1. Primrose, et al, "Principles of Gene Manipulation", Black Well Science, London, 20052. Becker, J.M., Caldwell, G.A. and Zachgo, E.A, "Biotechnology: A Laboratory Course", 2nd Edition, Academic Press Inc., San Diego,

California, 1996.

REFERENCE BOOKS:1. Wilson, K. and Walker, J, "Practical Biochemistry: Principles and Techniques", Cambridge University Press, Cambridge, 1997.2. Chirikjian, J.G, "Biotechnology: Theory and Techniques Vol. I Plant Biotechnology, Animal Cell Culture, Immunobiotechnology" Jones

and Bartlett Publishers, London, England, 1995.3. Sharma, B.K, "Instrumental Methods of Chemical Analysis", Goel Publishing House, Meerut, 1996.4. Sokal, R. R. and Rohlf, F.J, "Introduction to Biostatistic (Biology-Statistics Series)", W.H. Freeman & Company, New York, 1987.5. Forthofer, L, "Introduction to Biostatistics", Academic Press, New York, 1995.6. Thomas A. Mappes and David DeGrazia (editors),"Biomedical Ethics", McGraw Hill, 4th Edition, 1996


Max.Marks: 80 Exam Duration: 3 hrs





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