Sample Premium Expert Witness Profile Report

2020

PROVIDER DATA EXPERTS

727-667-9262

2

TABLE OF CONTENTS

Personal Information Page 4 Judgements and Liens Page 4-7 Licensing Information Licenses Page 8-9 License Discipline Actions Page 9 Other Discipline Actions Page 9 Education Information Schooling Page 10 Specialties / Certifications Page 10-11 Claimed Certification Courses Page 11-13 Expert Witness Agencies Expert Witness Agencies Page 13 From SEAK Page 13 From Juris Pro Page 14 David Mayer’s Fees Page 14-15 Experience Claims Page 15 Career History From Mayer Page 18 Current Medical Positions Page 19 Current Law Positions Page 20 Current Teaching Positions Page 20 Previous Medical Positions Page 21-24 Previous Law Positions Page 24 Previous Staff Positions Page 24-25 Career Details Professional Memberships Page 25 Other Memberships Page 26 Reviews Page 26 Health.usnews.com Page 27 Caredash.com Page 28 News Articles Page 29 Investigations Owned Entities Page 30 Possible Owned Entities Page 30 Medical Exclusion Agencies Page 31 State and Federal Exclusion / Sanction Agencies Page 31

3

Court Records Medical Malpractice Page 31-34 Court Cases-Other Page 34-38 Expert Witness Testimony Page 38-51 Daubert Challenges Page 52-56 Publication Activity Editorial Contributions Page 57 Book Chapters Page 57-58 Articles Page 58-60 Articles Awaiting Submission Page 60 Research Claimed Clinical Trials Page 61 Presentations Page 61-62 Scientific Exhibitor Events Page 63 Cited Publications Page 63-71

Attachments • Rutherford v Baltimore Washington Medical

Center Mayer Depo.pdf • Quinn v Mayer.pdf • Howe v Mayer.pdf • McEnaney v Mayer.pdf • Obadiah v Mayer.pdf • Carnevale v Mayer.pdf • Mayer v Shayani.pdf • Mayer v Frey.pdf • Mayer v Frey 2.pdf • David A Mayer Chapter 11.pdf • Denimarck v Jagust Mayer Transcript.pdf • Dellacamera v Tripodi Mayer Depo.pdf • Kinne v White Mayer Depo.pdf • Testaverdi v Leventhal Mayer Transcript.pdf • Chipman v Herbert Mayer Depo.pdf • Laney v Heifrich Mayer Affadavit.pdf • Guigno v Griffin Hospital Mayer Depo.pdf • Borut v Craig Mayer Transcript.pdf

• Sellars v Rosario Mayer Transcript.pdf • Hinlicky v O Frank Mayer Transcript.pdf • Esposito v Abbott Mayer Depo.pdf • Raj v Allendinger Mayer Depo.pdf • Carchia v Yale-New Haven Hospital Mayer

Depo.pdf • Leffler v Columbia Mayer Depo.pdf • Wall v Bridgeport Mayer Depo 2-8-05.pdf • Wall v Bridgeport Mayer Depo 3-7-05.pdf • MacDonald v Brown Mayer Transcript.pdf • Cruz v Benedicto Mayer Transcript.pdf • Marus v Semegran Mayer Transcript.pdf • Butler v Gorenstein Mayer Transcript.pdf • Butler v Gorenstein Other Witness

Transcript.pdf • Villanueva v Khan Mayer Testimony.pdf

4

DAVID ALAN MAYER, MD FACS

Other Names Mayer DA (For publishing) Known Addresses 956 Madeira Blvd Melville, NY 11747 27 Landview Drive Dix Hills, NY 11746 22 Wall Street Apartment 190 Huntington, NY 11743 20 Fox Meadow Lane Lloyd Harbor, NY 11743 (Sold on 02/07/2011 for $2,100,000) Ex-Wife Shirley Mayer Mobile 631-255-3304 Email Dmayer3091@aol.com Judgments and Liens Lien: The IRS placed a Federal Tax Lien against David A. Mayer at 22 Wall Street Apt 190 Huntington, NY 11743 on 09/18/2017 for $73,860.01

5

Lien: Dix Hills Air Conditioning Inc placed a lien against David A Mayer and Shirley Mayer on 01/09/2009 for $2,850 Judgement: A judgment against David A Mayer at 223 Wall Street, Apt 190 Huntington, NY on on 09/06/2016 by the Commissioner of Taxation & Finance for $10,152.82

Judgment: The Clerk of the Court for Suffolk County placed a judgment against David A Mayer at 27 Landview Drive Dix Hills, NY 11746 11/26/2014 for $105.00 (Traffic Related) – Corrected on 12/08/2014

6

Judgment: The Clerk of the Court for Suffolk County placed a judgment against David A Mayer at 956 Madeira Blvd Melville, NY 11747 on 07/31/2014 for $75.00 (Traffic Related)- Corrected on 12/08/2014

Judgement: A judgment against David A Mayer and Shirley Mayer at 956 Madeira Blvd Melville, NY on on 04/12/2013 by the Commissioner of Taxation & Finance for $898.37 -Satisfied on 04/28/2014

7

Judgment: The Workers Compensation Board of the State of New York placed a judgment against Minimally Invasive Surgery and David Mayer at 19 Southdown Rd Huntington, NY 11743 on 08/05/2013 for $76,000-Satisfied on 1/6/2016

Judgement: The Commissioner of Taxation & Finance judgment placed a judgement on David A Mayer and Shirley Mayer at 20 Fox Meadow Lane Lloyd Harbor, NY 11743 on 02/26/2009 for $16,165.33 – Satisfied on 10/19/2010

8

LICENSING INFORMATION

Licensees NPI # 1265471007 Issue Date 07/08/2007

Main Practicing State: New York License # 124152

License Type Physician Original License Issue Date 07/01/1975 License Status Licensed

Specialty Listed Surgery-General/Vascular Surgery Additional Medical License States: Florida License # ME86909

License Type Medical Doctor Original Issue Date 01/29/2003 Expiration Date 01/31/2009 License Status Null & Void Additional Medical License States: Florida License # ME31849

License Type Medical Doctor Original Issue Date 02/03/1978 Expiration Date 01/31/2009 License Status Authority Void

Additional Medical License States: Florida License # MEE5752

License Type Medical Expert Witness Original Issue Date 06/19/2018 Expiration Date 06/18/2020 License Status Null & Void Additional Medical License States: Florida License # MEE1760

License Type Medical Expert Witness Original Issue Date 02/19/2014 Expiration Date 02/18/2016 License Status Null & Void

9

Additional Medical License States: Florida License # MEE1234

License Type Medical Expert Witness Original Issue Date 06/25/2013 Expiration Date 06/24/2015 License Status Null & Void Law License Attorney License States: New York License # 4940664

Admission Date 05/25/2011 Expiration Date 01/01/2021 License Status Currently Registered License Discipline Actions New York Medical Board Discipline None Reported by the Board New York Department of Health None Reported by the Board Florida Medical Board Discipline None Reported by the Board Florida Department of Health Discipline None Reported by the Board New York State Unified Court System None Reported by the Board Other Discipline Actions Criminal Convictions, Pleas and Admissions None Reported by the Board Hospital Privilege Restrictions None Reported by the Board Hospital Failure to renew Privileges None Reported by the Board Out of State Board Discipline None Reported by the Board License Limitations None Reported by the Board

10

EDUCATIONAL INFORMATION

Schooling

Medical School Weill University Medical College Grad Date 1974 New York, N.Y

Residency The New York Hospital Dates 1974-1978 Cornell Medical Center Specialty Surgery Law School Hofstra University Grad Date 2010 Long Island, NY Master’s Degree Carnegie Melon Grad Date Unknown American College of Physicians Executives Specialty Medical Management Bachelor of Science Lafayette College Grad Date 1970 Easton, Pennsylvania Specialty

Specialties / Certifications American Board of Surgery Certification # 025124 Certification Area Surgery Initial Certification Date 09/12/1979 Expiration Date 12/31/2023 Status Certified- Clinically Inactive Participating in (MOC)* Yes Subspecialties None Listed Recertification Dates 10/26/1990, 10/22/1999,11/27/2012 * Maintenance of Certification

11

Certification Courses CO2 Laser Workshop for General Surgeons UMD Course Certification in the Use of CO2 Laser New Jersey 1988 Unconfirmed Duplex Scanning of the Carotid and Deep Venous System Ultrasonix Course Certification Yonkers, New Jersey 1986 Unconfirmed Transcranial Doppler Sonography Medasonics Course Certification Mountainview, California 1987 Unconfirmed Laparoscopic Laser Cholecystectomy E.J. Reddick, M.D., Course Certification Nashville, Tennessee 1990 Unconfirmed Advanced Laparoscopic Surgery including appendectomy, hernia repair, vagotomy, bowel resection and adhesio-lysis University of Medicine & Dentistry of New Jersey Course Certification Newark, New Jersey 1991 Unconfirmed

12

Laparoscopic Transperitoneal and Preperitoneal Hernia Repair Ethicon Course Certification New Jersey 1992 Unconfirmed Nissen Hiatal Hernia Repair Ethicon Course Certification New Jersey 2001 Unconfirmed American College of Surgeons Clinical Congress 1981 Unconfirmed Clinical Congress 1985 Unconfirmed Clinical Congress 1989 Unconfirmed Clinical Congress 1999 Unconfirmed Clinical Congress 2000 Unconfirmed Selected Readings in General Surgery (58 Category I CME credits a year) The University of Texas Southwestern Medical School Dallas, Texas 1974-Present Unconfirmed Sentinel Node Biopsy Moffitt Cancer Center Tampa, Florida 1997 Unconfirmed Laparoscopic Bowel Resection Course Medical Education Collaborative Bolder, CO 1998 Unconfirmed Laparoscopic Nissen Fundoplication Course Medical Education Collaborative Bolder, CO 1998 Unconfirmed BLS, ATLS, ACLS Certification Unconfirmed Mini-Fellowship in Bariatric Surgery Dr. Hans Schmidt-Hackensack Medical Center New Jersey 2005 Unconfirmed Top Gun Advanced Laparoscopic Suturing Course US Surgical Norwalk, CT 2006 Unconfirmed Lap-Band Course Inamed Chicago, IL 2005 Unconfirmed

13

Adipose Derived Stem Cell Therapy Cell Surgical Network Course Certification 2015 Unconfirmed SESAP 1 -12 American College of Surgeons Self-Assessment Program Course Certification Unconfirmed EXPERT WITNESS AGENCIES

Expert Witness Agencies SEAK Experts https://www.seakexperts.com/members/6769-david-a-mayer JurisPro https://www.jurispro.com/expert/david-mayer-md-fics-1823 National Medical Consultants No Profile for David Mayer, MD LexVisio https://www.lexvisio.com/expert-witness/david-a-mayer-md-facs-minimally-invasive-surgery-pc American Medical Forensic Services 1985 - 1995 No Profile for David Mayer, MD

From SEAK Expert Witness Website

General Specialties: General Surgery and Vascular Surgery Specialty Focus: General surgery, vascular surgery, bariatric surgery, breast cancer, trauma surgery, critical care and laparoscopic surgery expert. Number of Times Deposed/Testified in Last 4 Yrs: 20 Additional Information Chairman of Surgery Emeritus, Associate Professor of Surgery. Over 25 year’s experience as medical expert witness in all jurisdictions.

14

From JurisPro Expert Witness Website Dr. Mayer's areas of expertise include general surgery, vascular surgery, and bariatric surgery. He has over 35 years in practice and over 25 year’s experience as an expert witness. Dr. Mayer is an Associate Professor of Surgery at New York Medical College and Chairman of Surgery Emeritus at Northwell Syosset. Recorded Introduction https://www.jurispro.com/expert/david-mayer-md-fics-1823

This is Dr David Mayer. I am an expert in general, vascular and bariatric surgery. I have had 25 years of experience in case evaluation, deposition and trial testimony. I am, an associate professor of surgery -chairman of surgery at a major teaching hospital in New York state, and have 50 publications to my credit. I can be reached at 631-421-5151. Thank you. David Mayer’s Fees From a 2016 Deposition- Rutherford v Baltimore Washington Medical Center where David Mayer speaks about National Medical Consultants. (Attachment -Rutherford v Baltimore Washington Medical Center Mayer Depo.pdf) Q- “What is your fee for review of medical records?” A- “Well, this case was billed through National Medical Consultants, as you can see by the invoice, so they do a fair amount of billing for me, so I don't handle it directly, so -- so you probably have to refer to the invoices to see what the hourly fee is, et cetera.” Q- “Okay.So you do not know what your fee is for review of records? A- “ Well, it's generally 500 an hour for review

Q- “Okay. Do you charge any other fees for your forensic involvement in a case? A- “ Well, you know, trial fees.”

15

Q- “ Okay. What are your trial fees?” A- “ I think it's 6,000 for a day of trial.” Q- “And is that whether you go through National Medical Consultants or someone contacts you directly?” A- “ That would be as for this case. My fee could be 10,000 if I did not go through them.”

Experience Claims Mayer & Associates, PLLC 956 Madeira Blvd Melville, NY 11747 631-848-5535 From David Mayer’s Law License 223 Wall Street Suite 190 Huntington, NY 11743 877-417-0281 631-255-3304 www.DavidMayerMDLaw.com Note: website is not working, this address appears to be inactive Practice Areas:

• Medical Malpractice • Catastrophic Personal Injury

Member, Hofstra Law Review. (Also Of Counsel to Laurence M. Deutsch Law Firm, P.C., New York, New York Office)

16

From Lawyers.com https://www.lawyers.com/huntington/new-york/mayer-and-associates-p-l-l-c-157569565-f/ Areas of Law Automobile Accidents Cerebral Palsy Dental Malpractice Legal Malpractice Litigation

Medical Malpractice Personal Injury Slip and Fall Toxic Torts Wrongful Death

From LawyerDB.com http://www.lawyerdb.org/LawFirm/Mayer-Associates-Huntington/ Practice Areas: Automobile Accidents; Cerebral Palsy; Dental Malpractice; Legal Malpractice; Litigation; Medical Malpractice; Personal Injury; Slip and Fall; Toxic Torts; Wrongful Death. Facebook Comment from David Mayer, MD https://www.facebook.com/181597185231103/posts/david-a-mayer-md-associates-pllcmedical-malpractice-attorneys223-wall-street-sui/916770375047110/ DAVID A. MAYER, M.D. & ASSOCIATES, PLLC Medical Malpractice Attorneys 223 Wall Street, Suite 190 Huntington, New York 11743 Office: (631) 421-5151 dmayer3091@aol.com __________________________________ January 4, 2015 I am writing as one of Dr. Eric Braverman’s attorneys in the above-captioned custody matter recently decided before Judge Deborah Kaplan in Supreme Court, County of New York. Dr. Braverman has asked me to briefly summarize for you the salient points regarding possible judicial and/or attorney misconduct resulting in a hostile bench (at least to Dr. Braverman) that appeared to continually pander to attorneys from Raoul Felder’s firm as well to Susan Bender, the so-called attorney for the children who instead, to this observer, acted solely as a de facto member of Raoul Felder’s legal team often to her own clients’ detriment. The conduct of the trial, including the constant sustaining of Felder and Bender’s frivolous objections designed to delay and stonewall Defendant’s case, the Judge’s refusal to bring key forensic experts back to complete their examinations, and the imposition of progressively heinous sanctions for Dr. Braverman’s purported minor transgressions, resulted in quite an even playing field which fatally and prejudicially disadvantaged Dr. Braverman, all but guaranteeing an unjust outcome. In fact the outcome was not simply

17

unjust, it left the three Braverman boys in the sole custody of a mother who, according to a multitude of world class physician experts, endangered them through years of neglect and physical and sexual child abuse. The overall tenor of the case begs the question whether the entire system is flawed, requires judicial administrative review and a thorough overhaul. The following are a small sample of my observations which might prove useful: 1. The lead court-appointed forensic expert, Dr. Rodrigo Pizzaro, concluded that Dr. Braverman was delusional and could not tell whether Puss in Boots was a real or fictional character. He reached this absurd conclusion without administering a single psychiatric test to Dr. Braverman, in contravention of all prevailing ethical codes and standards of care promulgated by the American Psychiatric Society. He was at a loss to explain how Dr. Braverman was able to run a 50 member medical practice on Park Avenue in New York, to become a world renowned author and lecturer; and to be a confidant of Governors Pataki, Patterson and Cuomo while being psychotic and delusional. He was paid $158,000 for this incredibly unprofessional testimony which was enthusiastically endorsed and accepted as true by the Court. As a physician I was ethically bound to file a grievance regarding Dr. Pizzaro’s “paid for” fallacious testimony with the New York State Office of Professional Misconduct (currently pending before the OPMC). It was the first time I ever filed such a complaint regarding expert witness trial testimony. 2. The Court found that Dr. Braverman was dangerous to the children and guilty of medical child abuse because on numerous occasions he was forced to bypass a totally incompetent pediatrician to seek competent medical care for his three boys when they presented with various conditions and illnesses caused or exacerbated by the mother’s neglect and likely abuse. 3. Despite competent trial testimony from highly respected medical experts, the Court ignored evidence that the mother sent the children to Dr. Braverman for visitation with ticks embedded in their faces; needle marks on their foreheads with secondary infection and cellulitis; untreated strep throat; anemia from starvation; intentional hair cutting mimicking alopecia; and, bruised genitalia. Incredibly, Dr. Braverman was sanctioned and suffered a progressive loss of parenting time (eventually extremely limited visits supervised by child protective services) when he rushed the boys to emergency rooms and physicians for urgent medical care for such problems the mother had neglected (or caused through Munchausen’s by Proxy Syndrome). The Court concluded, against the weight of all credible evidence, that it was Dr. Braverman who committed medical child abuse by taking the boys to doctors thereby ensuring the boys received prompt and appropriate care. 4. Dr. Eli Newberger, a Harvard medical child abuse expert, testified that Daniel had a hematoma on his penis caused by an intentional pinch or bite that occurred on his mother’s parenting time. He stated that it was clear cut evidence of sexual child abuse. This testimony was ignored by the attorney for the children, and discounted by the Court. In fact, again I was ethically compelled as a mandated physician reporter in New York State to file a complaint against the mother with Child Protective Services for the presumptive abuse. CPS never even conducted a diligent investigation nor issued a finding on the matter. Roul Felder made a comment to Dr. Braverman in the hallway outside the courtroom that “[t]he kids’ penises can be cut off but as director of CPS in New York nothing would be done.” 5. On Dr. Braverman’s court-ordered sporadic visits with his boys (first at home then later at CFS headquarters) social workers began to “monitor” his visits. I observed that their reports were designed to find minor faults with his parenting and blow them way out of proportion so the Judge could progressively obstruct and limit his parenting time. I find no nefarious intent on the part of the social workers to hurt Dr. Braverman. I believe they were “just following orders” designed to facilitate the Court reaching the predetermined outcome.

18

6. I was present at a conference where the Judge concluded that Dr. Braverman should have further reduction in his parenting time because he allowed the boys to eat several harmless fish oil gummy bear vitamins. (I can enumerate a seemingly endless list of such counterintuitive rulings by the Court) As both an Associate Professor and Chairman of Surgery Emeritus at North Shore-LIJ as well as member of the New York trial bar, Dr. Braverman’s case offends me on multiple levels. He appears to have fallen victim to an unjust matrimonial court system in which attorneys like Roul Felder, Susan Bender and others, appear before the same Judges again and again, and manipulate the system, often to their own clients detriment, using the same court appointed experts (whose opinions are guaranteed by obscene fees and the promise of continuing future business) with the overarching goal of generating legal fees and profits for all players, with apparent disregard for just outcomes and ethical disposition of cases. How else can one explain the award of child custody to a neglectful mother who likely committed physical and sexual child abuse? How else can one explain medical decision making being taken away from a world class physician like Dr. Braverman? Please contact me should you wish to discuss this further. Sincerely, David A. Mayer, MD, JD CAREER HISTORY

From David Mayer related to his period of disability Q. You mentioned that you stopped operating because you went on a medical leave? A. Yeah. Q. Did you stop operating for any other reason? A. Oh, no. Q. And what did you do between December of 2010 when you began working at the surgicenter at the end of 2015? A. Well, I was fully disabled at the time with an orthopedic problem in the hip hat I eventually had operated and fixed, but I have a law degree from Hofstra Law School, so and I've been an expert for a while. So what I did in that interim was I taught at Hofstra Medical School in their structures course and I kept my clinical associate professor position at New York Medical College. So I was working with students and residents there and I was consulting with various law firms who would use me as expert and was helping them analyze cases as they were coming in and getting experts for hem, et cetera. I was doing my own expert work during that time, so I had a small law practice during that time handling like, you know, minor cases. I never had a law office or staff, so any cases I got in I referred to lawyers I knew, all with an eye toward recovering and getting back to the medical practice.

19

Current Medical Positions Advanced Robotic Hair Restoration Centers 1324 Motor Pkwy Suite 101 Hauppauge, NY 11749 631-215-3947 Position: Founder and Hair Restoration & Transplant Surgeon Note: Verbal confirmation confirmed he practices at this location From Advances Robotic Hair’s Website https://www.advancedrobotichair.com/provider/david-a-mayer-md About Dr. Mayer Board-certified surgeon, David A. Mayer, MD, brings more than 30 years of experience in hair restoration and hair transplants to Advanced Robotic Hair Restoration Centers, serving men and women in Hauppauge, New York, and throughout Suffolk County. Dr. Mayer began his professional pursuits at the Joan & Sanford I. Weill Medical College of Cornell University in New York City, where he earned his Doctor of Medicine, finishing first in his class. Following graduation, he completed a residency in surgery at New York-Presbyterian Hospital - Weill Cornell Medical Center in New York City. Before founding Advanced Robotic Hair Restoration Centers, Dr. Mayer practiced surgery for more than three decades, serving in the North Shore-Long Island Jewish (LIJ) Medical Center Health System in New York. He remains the director of surgery emeritus at one of these facilities and holds the academic rank of an associate professor of clinical surgery. Dr. Mayer is also an award-winning hair restoration expert. He’s performed thousands of hair restoration procedures during the course of his career and offers his patients state-of-the-art robotic hair replacement as a same-day procedure. Patients love spending time with Dr. Mayer because of his warm, welcoming bedside manner and great sense of humor. When he isn’t developing treatment plans or augmenting his professional skills, Dr. Mayer loves sharing his knowledge with others. He currently teaches at three New York area medical schools, is widely published in peer-reviewed medical literature, and regularly presents his research at conferences in the United States and abroad. Dr. Mayer welcomes patients experiencing thinning hair or hair loss to schedule an appointment at Advanced Robotic Hair Restoration Centers today

20

Current Law Positions David A. Mayer & Associates, P.L.L.C. 223 Wall Street Suite 190 Huntington, NY 11743 (631)421-5151 Lander and Cernigliarno, PC One Old Country Road Suite 400 Carle Place, NY 11514 516-742-6000 Position: Counsel Confirmed David A. Mayer, M.D., J.D., is of counsel to our firm. He is a summa cum laude graduate of Hofstra Law School and a member of the Law Review. A former Chairman and current Associate Professor of Surgery, Dr. Mayer had an active career as a practicing General, Vascular and Bariatric surgeon at hospitals in the North Shore-LIJ Health System until switching the focus of his career to protecting the rights of those injured by negligence and medical error. His current memberships include the New York State Bar Association, New York State Trial Lawyers Association, New York Academy of Trial lawyers, American Bar Association, and the American Association for Justice. http://landersandc.com/about-us.html Current Teaching Positions New York Medical College 40 Sunshine Cottage Rd Valhalla, NY 10595 914-594-4000 Position: Clinical Associate Professor of Surgery 1993 – Present Confirmed Hofstra Medical School 500 Hofstra Blvd Hempstead, NY 11549 516-463-7516 Position: Volunteer Teacher (Special Professor) 2014 - Present Confirmed Structures Course – Anatomy & Clinical

21

Previous Medical Positions Maxim Hair Restoration 15 Barstow Road Great Neck, NY 11021 (516) 447-7307 Note: Upon verbal query, the receptionist said David Mayer does not work there and that he left recently Maxim Cosmetic Surgery Clinic Address 903 Park Avenue New York, NY 10075 646-475-2099 Note: Upon verbal query, the receptionist said David Mayer does not work there From Maxim Cosmetic Surgery’s Website https://www.maximcosmeticsurgery.com/surgeons/david-a-mayer-md/ David A. Mayer, MD

• 30 Years’ Experience • Chief Executive Officer of the Patient Safety Movement Foundation • Executive Director of the MedStar Institute for Quality and Safety • Well-Known Critical Care and Laparoscopic Surgery Expert • Experienced in Nonsurgical (PRP Therapy) and Surgical Hair Restoration Procedures • Highly Regarded Director and Associate Professor Emeritus of Clinical Surgery • Renowned Expert in Regenerative Medicine • Pioneer in Stem Cell Therapy • Graduated at the Top of the Class at Weill Cornell Medical College • General Surgery Residency at New York Presbyterian Hospital – Cornell Campus

Procedures Performed:

• Hybrid Procedures (Combining Surgical and Nonsurgical Hair Restoration) • Stem Cell Therapy • Follicular Unit Transplant (FUT) Hair Transplants • Follicular Unit Extraction (FUE) Hair Transplants • Platelet-Rich Plasma (PRP) Therapy

22

North Shore University Hospital 300 Community Drive Manhasset, NY 11030 516-562-0100 Position: Attending Surgeon General, Vascular and Bariatric Surgery 1978 – 2010 Confirmed Huntington (NY) Noninvasive Vascular Laboratory Position: Medical Director 1978-2010 Confirmed From David Mayer

• Responsible for standardization of day-to-day operations of the Vascular Laboratory, including direct supervision of participating MD’s as well as the technical director and vascular technologists.

• Successfully directed accreditation process with the Intersocietal Commission for Accreditation of

Vascular Laboratories (ICAVL).

• Responsible for benchmarking and collection of data for quality assurance.

• Developed comprehensive policy and procedure manual for laboratory operations.

• Led implementation of process changes that were validated by Quality Assurance Program. Note: This is part of an umbrella corporation called The Center for General and Minimally Invasive Surgery LLC C/O Mayer & Co LLP, owned by Mayer North Shore/LIJ Syosset Hospital 221 Jericho Turnpike Syosset, NY 11791 516-496-6400 Position: Director of Surgery 2005-2008 Confirmed Position: Chairman 2005-2008 Confirmed From David Mayer

• Responsible for all quality assurance activities, credentialing, strategic planning within the Department of Surgery.

23

• All Chiefs of General Surgery, Vascular Surgery, Orthopedic Surgery, Obstetrics and Gynecologic Surgery, Plastic Surgery, etc report to the position of Director of Surgery, who also serves on the Medical Board and runs weekly morbidity and mortality conferences for the Department.

• Oversee minimally invasive/bariatric fellowship program.

Huntington (NY) Hospital Position: Medical Director, Surgical Intensive Care Unit 1995-2007 Confirmed From David Mayer

• Oversaw policy and procedures for the unit, including ongoing quality improvement initiatives.

• Led successful accreditation process conducted by Joint Commission for Accreditation of Healthcare Organizations (JCAH).

Position: Chairman, Critical Care Integrated Committee 1995-2007 Confirmed From David Mayer

• Led quality improvement initiatives that extensively reviewed structure and process issues in critical care units at Huntington Hospital.

• Led initiative for data collection and benchmarking throughout the North Shore Long Island Jewish Health System.

Standardization of intensive care practice at Huntington Hospital was achieved through ongoing evaluation and benchmarking with intensive care areas in the overall hospital network.

MDNY Healthcare Melville, NY Position: Member, Medical Delivery Committee 2002-2006 Confirmed From David Mayer

• Collaborate in development of quality initiatives, including alerts and disease management guidelines for HMO.

• Review drug formulary.

• Assess new medical technology.

24

Long Island Surgicenter Melville, NY Position: Chief of Surgery 2000 -2005 Confirmed From David Mayer

• As Chief of Surgery and member of Board of Directors, introduced state-of-art Chief of Surgery technology which attracted new MD surgeons to utilize facility.

• Assessed new technology in terms of its impact on patient care and the financial well-being of the

organization. Favorable risk assessment led to the creation of state-of-the-art laparoscopic surgery and orthopedic arthroscopy suites, facilitating recruitment of new MD surgeons.

• Created standards and credentialing tools for physicians, conducted monthly quality assurance reviews

and activities.

• Together with the Board of Directors, developed capital and operating budget Gurwin Jewish Geriatric Center Position: Director of Surgery and Wound Care 1985 - 2005 Unconfirmed Previous Law Positions Sanocki, Newman & Turret llp 225 Broadway #8 New York, NY 10007 212- 962-1190 Position: Counsel Confirmed Previous Staff Privileges North Shore/LIJ Syosset Hospital 221 Jericho Turnpike Syosset, NY 11791 516-496-6400 Huntington Hospital 270 Park Ave Huntington, NY 11743 631-351-2000

25

North Shore University Hospital 300 Community Drive Manhasset, NY 11030 516-562-0100 Plainview Hospital 888 Old Country Rd Plainview, NY 11803 516-719-3000 Stony Brook University Hospital 101 Nicolls Road Stony Brook, NY 11794 631-689-8333

CAREER DETAILS

Professional Memberships International College of Surgeons Fellow and Vice Regent New York Society for Cardiovascular Surgery Member American Society of Abdominal Surgeons Life Fellow Society for Minimally Invasive Therapy Member New York Metropolitan Breast Cancer Group Member Surgical Society of the New York Medical College Member Cell Surgical Network Member New York State Trial Lawyers Association Member New York Academy of Trial Lawyers Member American Association for Justice Member

26

Other Memberships New York Friar's Club Board of Governors South Huntington Jewish Center Board of Directors Suffolk Chapter of the American Cancer Society Board of Directors Y.M.C.A. of Huntington Board of Directors Reviews Review Site Review Average # of Reviews Vitals.com No Ratings 0 Healthgrades 4.7 24 MD.com No Ratings 0 Yelp No Rating 0 RateMds 4.0 2 Regenerative Medicine 5.0 1 Doctorschoice.com 5.0 3 Health.usnews.com Excellent 24

27

Health.usnews.com Note: U.S. News publishes patient experience ratings from Fountain Analytics, which aggregates patient reviews from over a hundred sites to compile information about 10 different patient experience metrics. These ratings are not intended as indicators of medical quality — how good a provider is — but rather reflect patients' feedback on factors such as good communication, clarity of instructions, etc. Patient experience ratings are issued in the context of a specific physician's specialty, as patients tend to rate types of providers differently.

28

Caredash.com

29

News Articles Sentinel Node Biopsy for Malignant Melanoma. Unconfirmed TV: Channel 4 Eyewitness News,1998 WLIR FM Radio Unconfirmed Series of Surgical Health Programs Vascular Surgery and Pacemakers - 1981 Hofstra University-Law News July 10, 2014 This article was inspired when Dr. Mayer was a student in Professor McGrath’s popular New York Civil Practice course at Hofstra Law. Dr. Mayer, a widely published and cited professor and chairman of surgery at New York Medical College, was struck by the unjust appellate reversal of the trial court’s decision in the case of Williams v. Nassau County Medical Center, which constitutes the centerpiece of the forthcoming article. https://lawnews.hofstra.edu/2010/09/22/prof-christopher-mcgrath-dr-david-mayer-co-author-article-to-appear-in-minnesota-journal-of-law-science-technology/ Parkview Stemcell A slideshow presentation – To Study adipose derived stem cells under IRB approved research protocols using customized equipment https://slideplayer.com/slide/10692185/

30

INVESTIGATIONS

Owned Entities Entity Name David A Mayer, M.D. & Associates PLLC ID# 4168638 Filing Date 11/22/2011 County Suffolk, NY Status Active Entity Name The Center for General and Minimally Invasive Surgery LLC C/O Mayer & Co LLP ID# 3221147 Filing Date 06/21/2005 County New York, New York Status Active Possible Owned Entity Entity Name Advanced Robotic Hair Restoration Centers, LLC Prior Entity Name Advanced Robotic Hair Replacement Centers, LLC ID# 5627686 Filing Date 09/25/2019 County Suffolk, NY Status Active Address 1324 Motor Parkway Suite 101 Hauppauge, NY 11749

31

Medical Exclusion Agencies Searched List of Excluded Individuals and Entities (LEIE) (Medicare) None Found New York Office of the Medicaid Inspector (NY’s Medicare) None Found Agency for Health Care Administration (Florida Medicaid) None Found State and Federal Exclusion / Sanction Agencies Searched Office of Inspector General-(HHS) Civil Monetary Penalties None Found US Department of Justice None Found Drug Enforcement Agency None Found Food & Drug Administration Citations None Found Food & Drug Clinical Disqualification Proceedings None Found Federal Bureau of Investigations None Found System for Award Management None Found

COURT RECORDS

Medical Malpractice

Counties Searched

Suffolk County (8) Found Date 01/07/1986 Court Supreme Court-State of New York, Suffolk County Case # 0013437/1982 Case Name Christopher Reinhart v David A Mayer, MD Nature of Suit Medical Malpractice Position Defendant Disposition Motion to Vacate Granted (Settled Before Trial) Status Closed

32

Date 11/05/1987 Court Supreme Court-State of New York, Suffolk County Case # 0022547 Case Name Jean Woods v David Mayer Nature of Suit Medical Malpractice Position Defendant Disposition Case Withdrawn (Settled Before Trial) Status Closed Date 09/28/1994 Court Supreme Court-State of New York, Suffolk County Case # 0009199/1994 Case Name Karen Quinn v David Mayer, MD Nature of Suit Medical Malpractice Position Defendant Disposition Verdict for Defendant Status Closed Attachment Quinn v Mayer.pdf Note: from a David Mayer Deposition for Guigno v Griffin Hospital et al I had done a breast biopsy on the patient which was incidental but the screening chest X ray was misread by the radiologist as normal, but it had a lung nodule that later turned out to be a missed lung cancer, and the radiologist settled, but for some reason the patient sued me, and I got a defendant's verdict at trial. That was about a year-and-a-half ago. Quinn was the patient's name, Karen Quinn. Date 08/16/1999 Court Supreme Court-State of New York, Suffolk County Case # 0010685/1999 Case Name Federico Norden v David A Mayer, MD Nature of Suit Medical Malpractice Position Defendant Disposition Settled Before Trial Status Closed Date 01/06/2003 Court Supreme Court-State of New York, Suffolk County Case # 0010173/2005 Case Name Caroline Howe v David Mayer, MD Nature of Suit Medical Malpractice Position Defendant Disposition Stipulation of Discontinuance Status Closed Attachment Howe v Mayer.pdf

33

Date 11/03/2003 Court Supreme Court-State of New York, Suffolk County Case # 99-10950 Case Name Edward McEnaney and Carolyn McEnaney v Huntington Hospital and David Mayer Nature of Suit Medical Malpractice Position Defendant Disposition Unknown Status Unknown Attachment McEnaney v Mayer.pdf Note: ORDERED that this unopposed motion by defendant Mayer for an order dismissing this action pursuant to CPLR 3 126 (sic) for want of prosecution is denied. By order, dated June 18,2003 (Burke, J.), the Court granted a motion by plaintiffs’ counsel for leave to withdraw subject to compliance with certain directives pertaining to service of that order upon the plaintiffs. By its terms the order also imposed a sixty day stay on the action. The period of the stay was to commence upon service of a copy of that order upon the plaintiffs. Defendant now moves for an order dismissing the action for want of prosecution contending that plaintiffs failed to appear when the matter was last called for trial on September 5,2003. At that time the matter was marked off the trial calendar. Counsel states he notified plaintiffs by letter, dated September 12,2003, that the matter had been marked off the trial calendar. Counsel argues that because plaintiffs have thus far failed to resume prosecution of the action, the matter should be dismissed. Defendant Mayer has, however, failed to support his motion with proof of the date that plaintiffs were served with the Court’s order, dated June 18,2003. Consequently, the Court cannot determine whether the stay provided for in that order is presently in effect and thus, the dismissal of this action for want of prosecution is precluded at this time. Date 01/26/2006 Court Supreme Court-State of New York, Suffolk County Case # 0010173/2005 Case Name Caroline & Albert Obadiah v David A Mayer, MD Nature of Suit Medical Malpractice Position Defendant Disposition Settled Before Trial Status Closed Attachment Obadiah v Mayer.pdf

34

Date 04/01/2010 Court Supreme Court-State of New York, Suffolk County Case # 06-32506 Case Name James Carnevale v Jalil Anwar md and David A Mayer, MD Nature of Suit Medical Malpractice Position Defendant Disposition Unknown Status Unknown Attachment Carnevale v Mayer.pdf Note: ORDERED that the motion by defendant David A. Mayer, for summary judgment dismissing the action as asserted against him, is granted, without opposition… Nassau County (2) Found Date 04/02/1987 Court Nassau Supreme Court Case # 0005991/1987 Case Name John Basta v David Mayer Nature of Suit Torts Negligence Position Defendant Disposition Case Withdrawn (Settled Before Trial) Status Closed Date 07/29/1998 Court Nassau Supreme Court Case # 0002301/1998 Case Name Kathy-Jo Devos v David A Mayer, MD Nature of Suit Medical Malpractice Position Defendant Disposition Withdrawn Status Closed Kings County None Found Queens County None Found Richmond County None Found New York County None Found Bronx County None Found Westchester County None Found

35

Court Cases - Other

Suffolk County (9) Found Date 05/03/1996 Court Supreme Court-State of New York, Suffolk County Case # 0009743/1996 Case Name David A Mayer v George M Gates Nature of Suit Equity Position Plaintiff Disposition Summary Judgment for Defendant Status Closed Date 08/08/1997 Court Supreme Court-State of New York, Suffolk County Case # 0019527/1997 Case Name Huntington Medical Group, Inc v David A Mayer Nature of Suit Other-Special Proceedings Position Defendant Disposition Plaintiff Summary Judgement Denied Status Closed Date 08/11/1997 Court Supreme Court-State of New York, Suffolk County Case # 0018313/1997 Case Name David A Mayer v Huntington Hospital Nature of Suit Other- Special Proceedings Position Plaintiff Disposition Unknown Status Closed Date 04/30/1999 Court Supreme Court-State of New York, Suffolk County Case # 0003465/1999 Case Name Huntington Medical Group, Inc v David A Mayer Nature of Suit Contract Position Plaintiff Disposition Unknown Status Closed

36

Date 03/02/1999 Court Supreme Court-State of New York, Suffolk County Case # 0028741/1998 Case Name David A Mayer v Huntington Medical Group, Inc Nature of Suit Contract Position Plaintiff Disposition Settlement Status Closed Date 07/19/2012 Court Supreme Court-State of New York, Suffolk County Case # 0009421/2012 Case Name David M Mayer v Steven Shayani, MD Nature of Suit Other- Real Property Position Plaintiff Disposition Settlement Status Closed Attachment Mayer v Shayani.pdf Note: There was most likely a typo with this case. New York State has not licensed an MD named David M Mayer, only David A Mayer, MD. Date 11/20/2014 Court Supreme Court-State of New York, Suffolk County Case # 0016087/2014 Case Name David A Mayer v Steven Shayani, MD Nature of Suit Other- Real Property Position Plaintiff Disposition Settlement Status Closed Date 08/12/2014 Court Supreme Court-State of New York, Suffolk County Case # 0027136/2013 Case Name David A Mayer, MD v Roger F Frey, MD & Joel M Schwartz, MD Nature of Suit Defamation Position Plaintiff Disposition Discontinuance with Prejudice Status Closed Attachment Mayer v Frey.pdf Mayer v Frey 2.pdf

37

Note: Plaintiff commenced this action to recover damages for alleged defamation arising out of the publication of an accusation by the defendants to the Central Judiciary Committee (CJC) of the American College of Surgeons. The accusation filed with the CJC alleged that Dr. Mayer had made false and misleading statements during his testimony as an expert witness at the trial of a medical malpractice action in which Dr. Frey and Dr. Schwartz were named defendants. Among the allegedly defamatory statements set forth in the complaint in this action are statements that “. . . Dr. Mayer was partial and prejudicial; misrepresented the standard of care; and was repeatedly untruthful”, that “Dr. Mayer repeatedly testified in a biased manner . . .”, and that “[Dr. Mayer’s statement was] factually incorrect and stated to prejudice the jury in the plaintiffs [sic] behalf’. Plaintiff also alleges in his complaint that defendants made the statements with malice. Defendants now seek an order dismissing the complaint for failure to state a cause of action on the ground that the statements made to the CJC are protected by privilege. Plaintiff has opposed the application. ….to the extent that a privilege may apply to the communications at issue, the allegation of malice set forth in the plaintiff’s complaint precludes dismissal of the complaint for failure to state a cause of action Date 06/04/2015 Court Supreme Court-State of New York, Suffolk County Case # 0002361/2015 Case Name David A Mayer v Michele D’A’rco Nature of Suit Other- Torts Position Plaintiff Disposition Settlement Status Closed Nassau County (2) Found Date 12/16/2005 Court Supreme Court-State of New York, Nassau County Case # 0018960/2005 Case Name David A Mayer v Administration for.. Nature of Suit Other Position Plaintiff Disposition Withdrawn Status Closed Date 02/16/2010 Court Supreme Court-State of New York, Nassau County Case # 0021548/2009 Case Name David A Mayer v Lloyd D Landsman Nature of Suit Other Position Plaintiff Disposition Verdict for Defendant Status Closed

38

Kings County None Found Queens County None Found Richmond County None Found New York County None Found Bronx County None Found Westchester County None Found Miscellaneous (1 ) Found Date 02/03/2017 Court United States Bankruptcy Court, Eastern District of New York Case # 8-15-73216 Case Name In re: David A Mayer Nature of Suit Chapter 11 Position Defendant Disposition Chapter 11 Dismissed Status Closed Attachment David A Mayer Chapter 11.pdf On July 29, 2015, Debtor filed this chapter 11 case. In his affidavit filed in accordance with Rule 1007-4 of the Local Bankruptcy Rules of this Court, Debtor stated his reason for filing for relief under chapter 11 – “[m]y current financial problems are due to a decline in my regular income and the results of an onerous divorce settlement.” Debtor is employed by and is the sole owner of David A. Mayer & Associates PLLC. On August 27, 2015, Debtor filed a motion seeking a declaration that no monies were owed to Movant under the Separation Agreement based upon the parties’ Alleged Oral Agreement and that he overpaid Movant by the sum of $70,061. On October 28, 2015, Movant filed a priority claim for prepetition unpaid domestic support obligations in the amount of $286,242.15. See Claims Register, Claim 6-2. Movant asserts that Debtor has failed to pay post-petition spousal and maintenance support, exclusive of attorneys’ fees, of at least $55,202.59. Debtor’s motion was adjourned on consent to allow Debtor and Movant to negotiate a consensual resolution. Having reached an impasse in their negotiations, Movant filed the Motion. Movant alleges four separate grounds for dismissal under § 1112(b)(1). She asserts that cause exists to dismiss this case due to Debtor’s (i) unexcused failure to comply with the reporting requirements set forth in Bankruptcy Rule 2015.3; (ii) failure to pay postpetition domestic support obligations; (iii) inability to effectuate a chapter 11 plan; and (iv) lack of good faith. The Court will address each ground in turn. For the reasons discussed above, the Motion is granted and Debtor’s chapter 11 case is hereby dismissed pursuant to 11 U.S.C. § 1112(b)(1).

39

EXPERT WITNESS TESTIMONY

1999 Date 11/04/1999 Court Supreme Court of New York, Suffolk County Case # 22357/96 Case Name Lisa Denimarck v Mark J Jagust, MD and Zosimo Ev Micabalo MD Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Denimarck v Jagust Mayer Transcript.pdf 2000 Date 09/06/2000 Court Connecticut Superior Court, Waterbury Case # X01 CV 96 0134612S Case Name John Dellacamera v Guiseppe Tripodi, MD et al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Dellacamera v Tripodi Mayer Depo.pdf 2001 Date 01/23/2001 Court Superior Court of Maine, Cumberland County Richmond County Case # CV 99 305 Case Name Daniel Kinne v Raymond R White, MD and Maine Medical Center Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Kinne v White Mayer Depo.pdf Date 06/14/2001 Court Supreme Court of New York, Richmond County Case # 12932/94 Case Name Ralph L Gelter (Testaverdi) v Harvey Leventhal MD, Victor Ho,

MD and Neuroscience Associates of New York Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Testaverdi v Leventhal Mayer Transcript.pdf

40

Date 07/17/2001 Court Superior Court of Maine, Cumberland County Case # Unknown Case Name Robert Chipman and Irene Chipman v William E Herbert, MD and

Main Surgical Care Group, Inc Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Chipman v Herbert Mayer Depo.pdf 2002 Date 02/01/2002 Court Unknown Case # Unknown Case Name Hattie Laney v Dr G Baird Heifrich Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Laney v Heifrich Mayer Affadavit.pdf 2003 Date 03/20/2003 Court Connecticut Superior Court, Ansonia-Milford Case # CV 98-00620338-S Case Name Maria Giugno v Griffin Hospital el al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Guigno v Griffin Hospital Mayer Depo.pdf Date 10/09/2003 Court Supreme Court of New York, Suffolk County Case # 24434/1998 Case Name Robert Borut and Frances Borut v Nicholas P Craig, MD Andrew N

Zeniou, MD North County Surgical, PC John T Mather Memorial Hospital

Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Borut v Craig Mayer Transcript.pdf

41

Date 12/04/2003 Court Supreme Court of New York, Suffolk County Case # 1000002/00 Case Name Melissa Cecera-Sellars and James Sellars v Mary Lucille Del

Rosario, MD and Huntington Medical Group Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Sellars v Rosario Mayer Transcript.pdf Date 12/12/2003 Court Supreme Court of New York, Broome County Case # RJI 99-0209-M Index 98-1393 Case Name Timothy J Hinlicky v Robert O Frank, MD, Surgical Associates, PC,

David Drefuss, MD and Riverside Associates in Anesthesia Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Hinlicky v O Frank Mayer Transcript.pdf 2004 Date 03/02/2004 Court Connecticut Superior Court, Hartford Judicial District Case # Unknown Case Name Carrie Esposito v Jay Abbott, MD Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Esposito v Abbott Mayer Depo.pdf Date 07/13/2004 Court Connecticut Superior Court, Hartford Judicial District Case # CV 02 0817093 S Case Name Irene Raj v Philip Allendinger MD, et al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Raj v Allendinger Mayer Depo.pdf

42

Date 08/10/2004 Court Connecticut Superior Court, New Britain District Case # Cv-03-0476048 S Case Name Americo R Carchia v Yale-New Haven Hospital, et al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Carchia v Yale-New Haven Hospital Mayer Depo.pdf 2005 Date 01/27/2005 Court Circuit Court of Illinois, Cook County Case # Unknown Case Name Lawrence Leffler v Columbia-Lagrange Memorial Hospital, et al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Leffler v Columbia Mayer Depo.pdf Date 02/08/2005 Court Superior Court New York Case # cv 00-0177329 S Case Name Susan Wall v Bridgeport Hospital Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Wall v Bridgeport Mayer Depo 2-8-05.pdf Wall v Bridgeport Mayer Depo 3-7-05.pdf Date 05/05/2005 Court Supreme Court of New York, Bronx Case # L-74-15 Case Name Area Macdonald and Joseph Brown v Chittur Mohan, MD

Westchester Vascular Associates, LLP Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment MacDonald v Brown Mayer Transcript.pdf

43

Date 08/09/2005 Court Supreme Court of New York, Kings County Case # 36074/02 Case Name Betsy Cruz v Ramon Benedicto, MD Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Cruz v Benedicto Mayer Transcript.pdf 2006 Date 01/17/2006 Court Supreme Court of New York, Westchester County Case # 2905-03 Case Name Lillian Marus v Village Medical, Adam Semegran, Vincent Bosco Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Marus v Semegran Mayer Transcript.pdf Date 02/01/2006 Court Supreme Court of New York, New York County Case # 101654/01 Case Name Bridget Butler and Richard Butler v Lyall A Gorenstein, MD et al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Butler v Gorenstein Mayer Transcript.pdf Butler v Gorenstein Other Witness Transcript.pdf Date 03/02/06 Court Supreme Court of New York, Bronx County Case # 21290/2000 Case Name Ralph Villanueva v Ivan Kahn, MD, Herzl Ragins, MD, NY Medical

Group, PC and Montefiore Center Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Villanueva v Khan Mayer Testimony.pdf

44

Date 04/25/2006 Court Circuit Court of Illinois, Cook County Case # 03 L 12955 Case Name Juan Maldonado v Ravenswood Hospital Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Maldonado v Ravenswood Mayer Depo.pdf Date 06/20/2006 Court Supreme Court of New York, Rockland County Case # 7253/2002 Case Name Barbara Elipoulos v HealthCheck, Inc et al (Including Roger Frey) Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Elipoulos v Healthcheck Mayer Depo.pdf Note: This is the case Mayer sued Dr Frey for defamation Date 07/13/2006 Court Supreme Court of New York, New Youk County Case # 113205-02 Case Name Felix Pichardo v Hapry R Schanzer, MD and Mount Sinai Medical

Center Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Pichardo v Schanzer Mayer Testimony.pdf Date 09/07/2006 Court Supreme Court of New York, Kings County Case # 22024/03 Case Name Maria Velonis v Michael Vitale, MD, Charles Jacob Stolar, MD,

Eric J Lazar, MD Ralph Mosca, MD and NY Presbyterian Hospital Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Velonis v Vitale Mayer Testimony.pdf

45

2007 Date 02/27/2007 Court Superior Court of Connecticut Case # NNH CV 05 4009963-S Case Name Jaqueline Wrobel v CBS Surgical group, PC et al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Wrobel v CBS Mayer Depo.pdf Date 04/24/2007 Court Circuit Court of Illinois, Rock Island County Case # 05 L 100 Case Name Morgan Brunstrom v Jason Jun-Gon Suh, MD Medical Arts

Associates, Afzal Abdullah, Christopher Cunningham, MD and Vascular & Thoracic Associates, LTD

Nature of Suit Medical Malpractice Position Expert Witness for Defendant Attachment Brunstrom v Suh Mayer Depo.pdf Date 07/3/2007 Court Superior Court of Connecticut, Litchfield Case # LLICV-05-500101S Case Name Karen Beyer v Stefanie Durstin, MD and Litchfield County

Obstetrics and Gynecology, PC Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Beyer v Durstin Mayer Depo.pdf Date 07/29/2007 Court Supreme Court of New York, Albany County Case # 3642-04 Case Name Rodney Hammond v Tejinder Singh and Albany Medical Center Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Hammond v Singh Mayer Transcript.pdf

46

Date 08/09/2007 Court US District Court for the Southern District of New York Case # 06CIV544 Case Name J Al-Hariri v Abe Minako, MD and David Riley MD, et al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Al-Hariri v Minako Mayer Depo.pdf Date 09/25/2007 Court Colorado District Court, Jefferson County Case # 2005cv2111 Case Name Shawn Blake and Lisa Blake v Carber Huang, MD Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Blake v Haung Mayer Depo.pdf 2008 Date 06/23/2008 Court Supreme Court of New York, Nassau County Case # 4495/04 Case Name Paula Caroppoli v Winthrop-University Hospital Association, Saul

M Modlin, MD et al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Caroppoli v Winthrop Mayer Transcript.pdf Date 08/19/2008 Court Superior Court if the District of Columbia Case # 2007-CA-002096 M Case Name Paulette Nielson v Washington Hospital Center Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Nielson v Washington Mayer Depo.pdf

47

2009 Date 07/23/2009 Court Superior Court of Connecticut, Hartford Case # CV 07 5009671 Case Name Anthony Gulan v Connecticut Surgeons, LLC Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Gulan v CT Surgeons Mayer Depo.pdf Gulan v CT Surgeons Depo of Paul P Lin MD.pdf Date 10/02/2009 Court Superior Court of Connecticut, New Britain Case # HHB CV 07 50047995 Case Name Kathy Broduer v Dr Abdel Richi, et al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Brodier v Richi Mayer Depo.pdf Date 10/09/2009 Court Circuit Court of Orange County Florida Case # 05-CA-9541-(35) Case Name Eunice Payne v Adventist Health Systems et al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Payne v Adventist Mayer Depo.pdf Date 11/04/2009 Court Superior Court of Connecticut, Waterbury Case # UWY CV 07 5005165-5 Case Name William Matkin v Mark Schoenfield Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Matkin v Schoenfield Mayer Depo.pdf

48

2010 Date 08/09/2010 Court Circuit Court of Michigan, Macomb County Case # 10-003607-NH Case Name Grace Nepa v Dr Abdelkader A Hawasii MD, el at Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Nepa v Hawasii Mayer Affadavit.pdf 2011 Date 10/26/2011 Court Georgia State Court, Wayne County Case # 08CV50202 Case Name Albert Paul Stephens v Dennis Davis, MD Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Stephens v David Mayer Depo.pdf 2014 Date 10/21/2014 Court Common Pleas Court of Philadelphia Case # 0623 Case Name Karen Crane v Andrew A Gumbs, MD and Fox Chase Cancer

Center Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Crane v Gumbs Mayer Transcript.pdf Date 10/26/2011 Court Supreme Court of New York, Nassau County Case # 12428/09 Case Name JoanMarie Glover v Henry Partridge, MD and Kenneth Becker,

MD Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Glover v Partridge Mayer Transcript.pdf

49

2016 Date 05/23/2016 Court Supreme Court of New York, Special Term, Erie County Case # 2013-000772 Case Name David M Flowers v David J Altman, MD Altman Dermatology PC

and Anil K Mahur, MD Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Flowers v Altman Mayer Transcript.pdf Date 09/14/2016 Court Supreme Court of New York, Special Term, Nassau County Case # 003062/12 Case Name Joselin Medina v David Aaron DO, Goof Samaritan Hospital

Medical Center, Steven Zimmerman, MD and Soujanya Tummuru, DL

Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Medina v Aaron Mayer Transcript.pdf 2017 Date 03/03/2017 Court Supreme Court of New York, Sullivan County Case # 2496-2007 Case Name Mira Longobardo and Anthony Longobardo v Abdul R Shahzad,

MD, Abdul R Shahzad, MD, PC, Surya Challa, MD , Surya Challa MD PC, et al

Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Disposition Settlement Attachment longobardo v_ Shahzad Mayer Transcript 3-13-17.pdf Longobardo v_ Shahzad Mayer Transcript 3-13-17. (2)pdf

50

Date 03/22/2017 Court Circuit Court of Anne Arundel County Case # c-02-CV-16-002412 Case Name Theodore E Rutherford, Jr v Baltimore Washington Medical

Center, Inc Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Rutherford v Baltimore Washington Medical Center Mayer Depo.pdf Date 04/26/2017 Court Superior Court of New Jersey, Law Division, Hunterdon County Case # L-74-15 Case Name John Sypa v Hunterdon Medical Center Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Sypa v Hunterdon Mayer Depo.pdf Date 07/12/2017 Court Supreme Court of New York, Special Term, Ontario County Case # 2017-010 Case Name Margaret L Monzon v John Porter, MD, Surgical Associates of the

Finger Lakes, Geneva General Hospital Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Monzon v. Porter Mayer Depo.pdf Date 09/13/2017 Court Supreme Court of New York, Onondaga County Case # 2014EF412 / 33-14-1864 Case Name Sandra Latimer v Atul Maini, MD and Upstate Surgical group, PC Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Latimer vs. Maini Mayer Transcript.pdf

51

Date 10/26/2017 Court Jefferson Circuit Court, Kentucky Case # 14-CI-003609 Case Name Norma Jean Troutman v Norton Hospitals, Inc et al Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Troutman v Norton Mayer Depo.pdf 2018 Date 01/09/2018 Court Circuit Court of the Thirteenth Judicial Circuit of Florida, Hillsborough County Case # 17-CA-003948 Case Name William C Livley v Gopal S Grandige, MD, Michael G Siegman,

MD, Suncoast Surgical Associates, PA and St Joseph Hospital Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Livley v Grandige Mayer Depo.pdf Date 10/04/2018 Court Indiana Superior Court, Marion County Case # 49D14-1603-CT-010927 Case Name Catherine Dudenhoeffer v. Todd M. Dudley, M.D.; Franciscan

Alliance, Inc.; Indiana Internal Medicine Consultants, PC; Jonathan A. Mendelbaum, M.D.; et al

Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Dudenhoeffer v Dudley Mayer Depo.pdf

52

Daubert Challenge Court Cases (14 ) Found Court Supreme Court New York County Case # 805347 Case Name Christine Laspalakis v Steven Weinfield and Mt Sinai Medical

Center Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Attachment Laspalakis v Weinfield.pdf Note: Plaintiff asserts that she has a meritorious action, and submits David Mayer, M.D.'s ("Dr. Mayer") Affidavit of Merit. Plaintiff argues that Defendants will not be prejudiced by the vacatur. Moreover, Plaintiff argues that she has provided Defendants with all outstanding discovery, she has set forth a reasonable excuse, and has demonstrated that she has a meritorious case. In opposition, Defendants contend that Plaintiff has failed to demonstrate that Defendants will not be prejudiced by the vacatur and that Plaintiff has a meritorious case. Defendants argue that Plaintiff "repeatedly ignored Court Orders" and Defendants attempted to obtain discovery since 2016. Defendants assert that the treatment rendered by Defendants was in 2014 and Defendants have not been able to obtain relevant records and interview crucial witnesses. Furthermore, Defendants argue that Dr. Mayer's Affidavit of Merit is insufficient to show that Plaintiff has a meritorious case. Defendants assert that Dr. Mayer is a general surgeon/bariatric surgeon with no expertise in the field of orthopaedic surgery, and Dr. Mayer's opinions are not based on the post-operative medical records but rather based on assumptions and hearsay. Defendants contend that Dr. Mayer incorrectly states that Plaintiff saw Dr. Weinfeld on twenty occasions post-operative and was seen by Dr. Weinfeld's "colleagues". Defendants assert that according to Dr. Weinfeld's post-operative treatment notes, Plaintiff was seen by Dr. Weinfeld on six occasions and was not seen by Dr. Weinfeld's "colleagues". Defendants contend that Dr. Mayer also fails to correctly state the antibiotic treatment Dr. Weinfeld provided to Plaintiff and Dr. Mayer's opinions are conclusory and not based on facts. Additionally, Defendants contend that Dr. Mayer states in a "conclusory fashion" that Defendants must have been negligent if Plaintiff was diagnosed with an infection by an outside physician and had surgery, four months after stopping treatment with Dr. Weinfeld. Defendants assert that Dr. Mayer incorrectly states that Plaintiff underwent "revision" surgery, when instead Plaintiff underwent surgery to remove hardware after the bone had healed. ORDERED that Plaintiff's motion to vacate the default judgment and restore the above referenced action is granted; and it is further ORDERED that the parties are to appear for a compliance conference scheduled for July 30, 2019 at 9:30 AM in Part 6; and it is further ORDERED that Plaintiff serve a copy of this order with notice of entry upon all parties and upon the Clerk of the Trial Support Office (Room 158).

53

Court Common Pleas Court of Philadelphia County, Pennsylvania, Civil Trial Division Case # 0.01473 / 1007001473 Case Name Bowser vs. Albert Einstein Med. Ctr. Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Testimony properly allowed; affirmed. Mayer was retained by the Plaintiff as an expert in the instant case. The Appellate Court observed that The trial Court erred and abused its discretion in denying Defendants' Motion for Judgment n.o.v. in their favour as to Plaintiffs' claim for future medical and related expenses or, in the alternative, Defendants' request for a remittitur of the award for future medical and related expenses, or a complete new trial due to the Court's underlying errors in denying Defendants' Motions in Limine seeking to bar Mrs. Bowser from recovering any amount for future medical expenses and seeking to bar Dr. Mayer from testifying beyond the scope of his pre-trial expert reports, in denying Defendants' Motion for Nonsuit and Motion for Directed Verdict, in allowing Dr. Mayer to testify beyond the scope of his pre-trial expert reports and in providing the jurors with instructions and a verdict sheet permitting a recovery of future medical and related expenses. The estimates set forth by Dr. Mayer as to future medical care were not supported by the evidence, were lacking in foundation and were completely incompetent. The Court erred and abused its discretion in allowing the jury to award future medical and related expenses based upon Dr. Mayer's speculative testimony . The Appellate Court held The Defendants' objections to the award of future medical expenses are without merit. The judgment was affirmed on appeal. Note: On July 19, 2007, plaintiff Leola Bowser, 56, underwent a subtotal gastrectomy performed by general surgeons Paul Steerman and Joseph Grisafi at Albert Einstein Medical Center in Philadelphia. Court Common Pleas Court of Philadelphia County, Pennsylvania, Civil Trial Division Case # 0.01473 / 1007001473 Case Name Barbara Eliopoulas v Healthcheck, Inc Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Testimony challenged as being speculative at appeal; outcome unknown. Note: Mayer was retained by the Plaintiff as an expert in the instant case. According to the Brief For Defendants-Appellants it was argued that his testimony was speculative as to how the stroke was caused. The outcome of Defendants challenge regarding his testimony is unknown. Court Superior Court Of Arizona Case # CV 2008-054988 Case Name Elwartowski V. Banner Health, Inc. Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff

54

Note: David A Mayer’s Testimony was challenged in this case. Motion to strike filed; outcome unknown. Note: Mayer was retained by the Plaintiff as a general surgeon in the instant case. Defendant filed a motion to strike his testimony. The outcome of Defendants motion to strike his testimony is unknown. Court United States District Court for the Northern District of Illinois, Eastern Division Case # 14-cv-10117 Case Name Johnson vs. Estate of Saleh Obaisi & Wexford Health Sources Nature of Suit Civil Rights Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Testimony partly sufficient and partly insufficient to defeat summary judgment motion. Court Ohio Common Pleas Court, Lucas County Case # G-4801-CI-200707088 Case Name Kenneth T Duty V. Bay Park Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Motion in limine to exclude filed; outcome unknown. Court Supreme Court Of New York Case # 06-16457 Case Name McDonald V. Branch Pediatric & Adolescent Group, P.C. Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Motion to preclude filed; outcome unknown. Note: Mayer was retained by the Plaintiff as an expert in the instant case. Defendant filed a motion to preclude him from testifying to departures and the standard of care applicable to the Defendants in the present case as it was outside the area of his expertise. Court Circuit Court Of Illinois, County Department, Law Division Case # 09L11346 Case Name Moore V. Rush University Medical Center Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Motion in Limine to bar denied.

55

Court Superior Court Of Massachusetts Case # 1573CV01086 Case Name Paiva V. Randy Kaplan Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Motion in limine to preclude filed; outcome unknown. Court Court Of Common Pleas Of Pennsylvania Chester County Case # 03-05371 / 2004 WL 6028212 Case Name Phillips V. Brandywine Hospital Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Motion in Limine to preclude filed; outcome unknown. Note: Mayer was retained by the Plaintiff as an expert in the instant case. Defendant filed a motion in limine to preclude his testimony arguing that he was not qualified to testify as to the standard of care applicable to Dr. Budier, Dr. Gammiantoni and Brandywine Surgical Group. Defendant further stated that during his trial testimony, he had rendered an opinion on the subject and discussed differing medications and routes of administration which were never disclosed in his report. The outcome of Defendants motion in limine to preclude his testimony is unknown. Court Superior Court Of Rhode Island Case # KC97-1077,98-1049 Case Name Potter V. Hughes Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Motion to exclude filed; outcome unknown. Note: Mayer was retained by the Plaintiff as an expert in the instant case. Defendant stated that the Court should exclude his affidavit since it failed to meet the requirements of R.I.G.L. §9-19-27. Court United States District Court, E.D. Pennsylvania Case # 2:15-CV-06749 Case Name Robinson V. Delaware County Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Objection regarding deposition partly overruled.

56

Note: The Court overruled Defendants objection regarding Plaintiffs expert Mayers deposition in part. Court United States District Court, C.D. California Case # 8:17-CV-00201 Case Name Torralbo V. Davol, Inc. Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Objection regarding testimony filed; not ruled upon due to termination of the suit. Court Supreme Court, Appellate Division, Second Department, New York Case # 2007-01799 Case Name Velonis V. Vitale Nature of Suit Medical Malpractice Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Motion to strike granted at trial; outcome of appeal is unknown . Note: Mayer was retained by the Plaintiff as a general and vascular surgeon in the instant case. According to the Brief for Plaintiff-Appellant it was stated that Upon a motion to strike the testimony of Dr. Mayer, Plaintiffs expert in general and vascular surgery, Justice Levine outright dismissed Defendants Drs. Stolar, Lazar, Mosca and Presbyterian from the case. The trial judge had quoted upon Defendants motion to strike his testimony that Based on the testimony of Doctor Mayer, whose testimony was in many ways tainted by his own admissions, that he presented himself as a board certified vascular surgeon when he wasn't and that was further presented by the hospital from his representation after finding out that it was contained in the record he did nothing about it either since January 2006 or some other time, it still contains in the record by his admission in Huntington Hospital. I just feel that his presentation here was so poor and so unbelievable that I cannot in good conscience give to the jury any interrogatory regarding the surgeons who did the repair. Motion is granted. Plaintiff contended that Justice Levine's determination that the testimony of Plaintiffs expert, Dr. Mayer, was unbelievable, was reversible error since it was beyond dispute that issues of witness credibility and proximate cause were for the jury and not for the judge. The outcome of appeal is unknown. Court U.S. Court Of Federal Claims Case # 1:16-VV-01641 Case Name Worcester V. Secretary of Health And Human Services Nature of Suit Civil Position Expert Witness for Plaintiff Note: David A Mayer’s Testimony was challenged in this case. Testimony struck.

57

PUBLICATION ACTIVITY

Editorial Contributions Preventing Balloon Catheter Associated Arterial Injuries. Surgical Capsule & Comment. Mayer, D.A., Contributing Editor Vol 8(6), 1989 Minimal Access Surgical Anatomy Archives of Surgery, 136(10):115, 2001 Mayer, D.A. et al. Book Review Carotid Endarterectomy in Nonagenarians. Mayer, D.A. Invited Critique Archives of Surgery. 140:628, 2005 Book Chapters Book Chapter-Aspects of Human Parasites in Which Surgical Intervention May Be Important Mayer, D.A., and Fried, B Advances in Parasitology. 51:1-94, 2002 Abstract Until recently, physicians and surgeons in developed countries only occasionally encountered patients with parasitic protozoan and helminthic infections. High-speed travel, immigration and the popularity of the tropics as vacation areas have increased the number of people at risk for parasitic disease. This chapter examines the significant literature on a select number of protozoan and helminthic parasites for which surgical intervention is important in the diagnosis, treatment or cure of the disease. Although traditional surgical approaches are covered, emphasis is placed on recent advances in the areas of transplantation and minimally invasive surgery. Combining the disciplines of parasitology and surgery, this chapter covers three protozoan and seven helminthic parasites for which surgery is a valid treatment option based on the frequency of cases reported in the literature. Following coverage of the selected parasites, a table is included listing additional helminths for which surgery contributes to patient management. Physicians in the USA, UK, and Europe need to be more aware of the presentation and treatment of parasitic infections. It is our sincere hope that this review accomplishes that goal, and ultimately benefits the patients we serve. https://pubmed.ncbi.nlm.nih.gov/12238889/ Book Chapter: The Role of Helminth Infections in Carcinogenesis. Mayer, D.A., and Fried, B. Advances in Parasitology. 65: 239-96, 2007

58

Abstract This review examines the significant literature on the role of helminth infections in carcinogenesis. Both parasitic infections and cancer have complex natural histories and long latent periods during which numerous exogenous and endogenous factors interact to obfuscate causality. Although only two helminths, Schistosoma haematobium and Opisthorchis viverrini, have been proven to be definitely carcinogenic to humans, others have been implicated in facilitating malignant transformation. The known mechanisms of helminth-induced cancer include chronic inflammation, modulation of the host immune system, inhibition of intracellular communication, disruption of proliferation-antiproliferation pathways, induction of genomic instability and stimulation of malignant stem cell progeny. Approximately 16% of all cancer cases worldwide are attributable to pathogenic agents, including schistosomes and liver flukes. This equates to 1,375,000 preventable cancer deaths per year. Means to reduce the incidence of helminth-associated malignancies are discussed. https://pubmed.ncbi.nlm.nih.gov/18063098/ Book Chapter: A review of selected helminths involved in human carcinogenesis. Mayer, D.A., Aditya Reddy, and Fried, B. Invited contribution in Cancer Letters, Spring, 2010 Articles Infectivity of Leucochloridiamorpha constantiae in the chick and on the chorioallantois Mayer, D.A., and Fried, B. Journal of Parasitology, 58(2):213-6, 1972 Carcinoma of the Gastric Cardia and Hiatal Hernia Mayer, D.A., et. Al Journal of Thoracic and Cardiovascular Surgery, Vol 71(4):592, 1976 Pacemakers: Dual versus Single Chamber Implantation Mayer, D.A., and Tsapogas, M.J. Vascular Surgery, 26(5):400-7, 1992 Duplex Scanning of e-PTFE Dialysis Shunts: Impact on Patient Management and Graft Survival. Mayer, D.A., and Tsapogas, M.J. Vascular Surgery, 27(9):647-58, 1993 Effect of Povidone-Iodine on Wounds. Mayer, D.A. Wounds, 5(1):14-23, 1993

59

Gluteal Abscess: An Unusual Presentation of Spontaneous Retroperitoneal Perforation in Crohn's Disease. Mayer, D.A., and Tsapogas, M.J. Ostomy/Wound Management, 39(5):30-34, 1993 Peritoneoscopic Placement of CAPD Catheters. Mayer, D.A., and Zingale, R.G. Society of Laparoendoscopic Surgeons Report, Winter 93 Necrotizing Pancreatitis: Improved Survival. Mayer, D.A., and Tsapogas, M.J. American Journal of Gastroenterology, 89(9):1659, 1994 Conflicting Points of View Regarding the Use of Povidone Iodine. Mayer, D.A. Osteotomy – Wound Management. Vol 40(8):6-8, 1994 Surgeon Beware: Bladder injury during TAPP Laparoscopic Inguinal Herniorrhaphy. Mayer, D.A. Society of Laparoendoscopic Surgeons Report, Winter, 1995 Central Venous Puncture versus Cutdown for Permanent Pacemaker Lead Insertion: A Modified Double Introducer Technique. Mayer, D.A., and Kolker, A Minerva 4 Cardiolangiol. Vol 44(1-2): 39-44, 1996 Modified Cephalic Vein Guide Wire Technique for Pacemaker Lead Introduction. Mayer, D.A., and Kolker, A. Journal of Cardiovascular Surgery, 1996 Leiomyosarcoma of the Pulmonary Vein Mayer, D.A., et al. Journal Cardiovascular Surgery, 37:421-3, 1996 Tips Offered for Handling Iatrogenic Bladder Injuries. Mayer, D.A., and Patane, J. Laparoscopic Surgery Update, Vol 4(2):16, 1996 Spontaneous Idiopathic Rupture of the Urinary Bladder. Mayer, D.A., et al. Urology - 5/98

60

Leiomyosarcoma of the Pulmonary Vein. Mayer, D.A., et al. Proceedings of Second International Congress on Coronary Artery Disease. Florence, Italy. Oct 18-21, 1998 Self Expanding Knitted Polypropylene Mesh Facilitates Laparoscopic Inguinal Herniorrhaphy. Mayer, D.A., and Steinberg, S. Journal of Laparoendoscopic and Advanced Surgical Techniques, 9(4):371-2, 1999 Pacemaker Leads. A Simple Atraumatic Method for Replacing Pacemaker Electrodes. Mayer, D.A., and Steinberg, S. Annals Thoracic Surgery, 70:1428, 2000 Balloon Blunt Tip Trocar for Laparoscopic Cholecystectomy: Improvement over Traditional Hassan and Veress Needle Methods. Mayer, D.A., et al. Journal of Laparoendoscopic and Advanced Surgical Techniques, 11(2):73-8, 2001 Self Expanding Knitted Polypropylene Mesh versus Standard Marlex for Laparoscopic Inguinal Hernia Repair. Mayer, D.A., and Steinberg, S. Journal of Laparoendoscopic Surgery, 2001 Repair of Post-CABG Subxiphoid Hernias with Mesh Plug Technique. Mayer, D.A., and Steinberg, S. The Annals of Thoracic Surgery, 2005 Repair of Post-CABG Subxiphoid Hernias with Mesh Plug Technique. Mayer, D.A., and Steinberg, S. The Annals of Thoracic Surgery, 2005 And Justice for All: An Alternative Decision to Williams v. Nassau County Medical Center to Ameliorate the Harsh Impact of New York’s Late Notice of Claim Statute on Infant Medical Malpractice Plaintiffs. Mayer, D.A. and McGrath, C. 12(1) Minnesota J. of Law, Science & Technology 23-59 (2011). Articles Awaiting Submission Open Roux-en-Y Gastric Bypass: An Ideal Operation for a Community Hospital-based Bariatric Program. Mayer, D.A., et al. Awaiting submission in Journal of Surgery for Obesity and Related Diseases

61

RESEARCH ACTIVITY

Claimed Clinical Trials Note: These clinical trials may not be registered under the names provided or may be subsets of a registered clinical trial. Phase 5 PAIRED Trial of N-Pacemaker Telemetry in early detection of atrial fibrillation - 2005. Position: Principal Investigator Not Found Phase 5 ER2 Trial comparing emotional response versus accelerometer technology in rate response of pacemakers - 2005. Position: Principal Investigator Not Found Principal Investigator: IRB for Human Adipose Derived Stem Cell Therapy – 2015, ongoing. Position: Principal Investigator Not Found Presentations Laparoscopic Inguinal Hernia Repair Made Easy With Self Expanding Mesh. Mayer, D.A. Proceedings of 9th International Congress of EAES. Maastricht, NE. June 13-16, 2001 Subxiphoid Post-Sternotomy Incisional Hernia: A Simplified Mesh Plug Repair. Mayer, D.A., et al. Proceedings of 4th International Congress on Coronary Artery Disease. Prague, CZ. Oct 21-24, 2001 Pacemaker Leads. A Simple Atraumatic Method for Replacing Pacemaker Electrodes. Mayer, D.A., et al. Proceedings of 3rd International Congress on Coronary Disease - Lyon, France, 2000

62

A Rare Tumor of the Pulmonary Vein. Mayer, D.A., et al. Proceedings of International Academy of Cardiology. First International Congress on Heart Disease. Washington, D.C. May 16-19, 1999 Recognition of the Acute Abdomen in the Bariatric Patient North Shore - LIJ Plainview, 2007 Current Trends in Bariatric Surgery Grand Rounds, Huntington Hospital, NY 2006 Abdominal Compartment Syndrome Grand Rounds, Huntington Hospital, 2005 Sentinel Node Biopsy for Malignant Melanoma Nassau-Suffolk Oncology Association Annual Meeting, 1998 Peritoneoscopic Placement of CAPD Catheters Video Presentation: The Society of Laparoendoscopic Surgeons - International Video Festival, August 19-20, 1994, Maui, Hawaii. Laparoscopic Placement of Permanent PD Catheters. Video Presentation: Fall Meeting, Society of Laparoendoscopic Surgeons, 1993, Orlando, Florida. Breast Cancer Update National Cancer Society, Long Island Division,1984 Pacemaker Mediated Tachycardia Eastern Long Island Chapter of the American College of Surgeons,1983 Management of Liver Trauma Eastern Long Island Chapter of the American College of Surgeons - 1978

63

Scientific Exhibitor Events Mesh Plug Repair of Subxiphoid Post CABG Hernias. Scientific Exhibitor - American College of Surgeons, Chicago, Ill. Fall, 2000 Self Expanding Polypropylene Mesh Facilitates Laparoendoscopic Inguinal Hernia Repair. Scientific Exhibitor - American College of Surgeons Meeting, San Francisco, 1999 Improved Mesh Placement for Laparoscopic Herniorrhaphy. Scientific Exhibitor - American College of Surgeons. New York City. Fall, 1999 The Effect of Povidone-Iodine on Wounds. Scientific Exhibitor - Clinical Congress of American College of Surgeons, Atlanta, Georgia - 1989 Cited Publications Hepatic vein reconstruction in ex situ split-liver transplantation. Noujaim HM, Mirza DF, Mayer DA, De Ville De Goyet J. Transplantation. 2002 Oct 15;74(7):1018-21. doi: 10.1097/00007890-200210150-00021.PMID: 12394848 Abstract Background: Anatomy of the left hepatic vein (LHV) was studied in a series of 53 consecutive cadaveric liver grafts that were divided for transplantation. Methods: All divisions were performed ex situ and provided a left split graft with only the LHV as the hepatic outflow. The anatomy was categorized into three types: (A) single LHV trunk, (B) two veins closely merging toward the median hepatic vein, or (C) a double outflow. Results: Direct implantation of the graft was performed in type A and was possible in type B after simple plasty of the ostia to create a single orifice. In type C, a venous jump graft could be interposed at bench work to allow direct anastomosis into the recipient. There were no related complications, except one type A case with late outflow obstruction. Conclusion: Liver division can be performed safely in liver grafts with variant LHV anatomy, if appropriate techniques for reconstruction are used. Also ex situ liver division has the advantage of allowing a detailed anatomic evaluation before dividing LHV: reconstruction can be performed ex situ, allowing a single-step direct anastomosis in the recipient, thus shortening suturing time. https://pubmed.ncbi.nlm.nih.gov/12394848/?from_term=david+a+mayer&from_size=200&from_pos=1

64

The role of helminth infections in carcinogenesis. Mayer DA, Fried B. Adv Parasitol. 2007;65:239-96. doi: 10.1016/S0065-308X(07)65004-0.PMID: 18063098 Review. Abstract This review examines the significant literature on the role of helminth infections in carcinogenesis. Both parasitic infections and cancer have complex natural histories and long latent periods during which numerous exogenous and endogenous factors interact to obfuscate causality. Although only two helminths, Schistosoma haematobium and Opisthorchis viverrini, have been proven to be definitely carcinogenic to humans, others have been implicated in facilitating malignant transformation. The known mechanisms of helminth-induced cancer include chronic inflammation, modulation of the host immune system, inhibition of intracellular communication, disruption of proliferation-antiproliferation pathways, induction of genomic instability and stimulation of malignant stem cell progeny. Approximately 16% of all cancer cases worldwide are attributable to pathogenic agents, including schistosomes and liver flukes. This equates to 1,375,000 preventable cancer deaths per year. Means to reduce the incidence of helminth-associated malignancies are discussed. https://pubmed.ncbi.nlm.nih.gov/18063098/?from_term=david+a+mayer&from_size=200&from_pos=2 Web-based image transmission: a novel approach to aid communication in split liver transplantation. Bhati CS, Wigmore SJ, Reddy S, Mayer DA, Buckels JA, Derek M, Mirza DF. Clin Transplant. 2010 Jan-Feb;24(1):98-103. doi: 10.1111/j.1399-0012.2009.01125.x. Epub 2009 Oct 30.PMID: 19878514 Abstract Background: Split liver transplantation (SLT) is technically demanding and requires good communication between transplant centers. The recipient surgeon receiving a shipped split liver needs detailed information on allocation of inflow and outflow vessels. We describe the first use of an image transmission system to facilitate SLT. Methods: Twenty cadaver livers undergoing ex situ splitting were studied. Fifteen were shared between the geographically separate Birmingham adult and pediatric centers and five were shared with other UK centers. Results: A total of six to eight images of each split graft were taken with a camera at standardized settings using the National Organ Retrieval Imaging System (NORIS), showing details of appearance, size, and anatomy of allocated inflow and outflow vessels. These were uploaded using a personal digital assistant to a secure website (http://www.noris.org.uk). The remote recipient surgeon then viewed these images by logging onto the password-protected website. Minimum time interval between division of the hilar vessels and completion of the split procedure was two h, allowing remote surgeon to view their allocated "shipped" graft in advance of commencing surgery. Conclusion: This advanced yet simple image transmission system has the potential for routine application in transplant surgery, not only for splitting but also for reporting injuries and graft steatosis. https://pubmed.ncbi.nlm.nih.gov/19878514/?from_term=david+a+mayer&from_size=200&from_pos=3 Combined liver-intestine grafts compared with isolated intestinal transplantation in children: a single-center experience. Dopazo C, Gupte GL, Sharif K, Perera MT, Hartley J, Muiesan P, Mayer DA, Bromley P, Bennett J, Kelly DA, van Mourik I, McKiernan P, Beath SV, Mirza DF. Transplantation. 2012 Oct 27;94(8):859-65. doi: 10.1097/TP.0b013e318265c508.PMID: 23018880 Abstract Background: Intestinal transplantation is known to be associated with a high risk of early complications and mortality.

65

Methods: We analyzed prospective data of 51 primary small bowel transplantations from December 1999 to August 2009 and identified perioperative factors that impact on early mortality (≤6 months after transplantation) after isolated intestinal (IITx; n=12) and combined liver-intestinal transplantation (CLITx group; n=39). Results: Ten patients died during the first 6 months after transplantation, all of them in CLITx group (n=10/51, 19%). Multivariate analyses demonstrated intraoperative red blood cell transfusion greater than 70 mL/kg (P=0.019, odds ratio [OR]=13.79) and base excess 30-min after reperfusion less than -16 (P=0.001, OR=14.05), thrombocytopenia (<50,000 per dL) between day 1 and day 15 after transplantation (P=0.047, OR=5.22), and occurrence of vascular complications (P=0.003, OR=8.96) during the posttransplantation period as predictors of early mortality in CLITx group. Conclusion: Risk of mortality at 6 months after intestinal transplantation increased when the liver is included as combined graft. Strategies to reduce mortality such as refining selection for transplantation and early referral before the development of liver failure should be a priority. Aspects of human parasites in which surgical intervention may be important. Mayer DA, Fried B. Adv Parasitol. 2002;51:1-94. doi: 10.1016/s0065-308x(02)51003-4.PMID: 12238889 Review. Abstract Until recently, physicians and surgeons in developed countries only occasionally encountered patients with parasitic protozoan and helminthic infections. High-speed travel, immigration and the popularity of the tropics as vacation areas have increased the number of people at risk for parasitic disease. This chapter examines the significant literature on a select number of protozoan and helminthic parasites for which surgical intervention is important in the diagnosis, treatment or cure of the disease. Although traditional surgical approaches are covered, emphasis is placed on recent advances in the areas of transplantation and minimally invasive surgery. Combining the disciplines of parasitology and surgery, this chapter covers three protozoan and seven helminthic parasites for which surgery is a valid treatment option based on the frequency of cases reported in the literature. Following coverage of the selected parasites, a table is included listing additional helminths for which surgery contributes to patient management. Physicians in the USA, UK, and Europe need to be more aware of the presentation and treatment of parasitic infections. It is our sincere hope that this review accomplishes that goal, and ultimately benefits the patients we serve. https://pubmed.ncbi.nlm.nih.gov/12238889/?from_term=david+a+mayer&from_size=200&from_pos=5 Embryonal rhabdomyosarcoma of the ampulla of Vater in early childhood: report of a case and review of literature. Perera MT, McKiernan PJ, Brundler MA, Hobin DA, Mayer DA, Mirza DF, Sharif K. J Pediatr Surg. 2009 Feb;44(2):e9-e11. doi: 10.1016/j.jpedsurg.2008.10.113.PMID: 19231522 Review. Abstract Embryonal rhabdomyosarcoma of the ampullary region is a very rare childhood tumor (2 reported cases), and herein we describe a child presenting with obstructive jaundice at early age owing to such tumor in the ampullary region. Successful management with multidisciplinary approach is discussed with reference to the literature. https://pubmed.ncbi.nlm.nih.gov/19231522/?from_term=david+a+mayer&from_size=200&from_pos=6

66

Renal function recovery in children undergoing combined liver kidney transplants. Perera MT, McKiernan PJ, Sharif K, Milford DV, Lloyd C, Mayer DA, Kelly DA, Mirza DF. Transplantation. 2009 May 27;87(10):1584-9. doi: 10.1097/TP.0b013e3181a4e710.PMID: 19461498 Abstract Background and method: Combined liver kidney transplant (CLKT) is a recognized treatment option for end-stage renal disease due to primary hyperoxaluria (PH-I) and cystic disorders, yet there is only limited data on posttransplant renal function recovery. The objective of this study was to assess postoperative renal function of children with PH-I (group A) undergoing CLKT and to compare this with a cohort of children (group B) who received CLKT for other indications. Results: Twenty-three patients underwent CLKT between 1994 and 2008 (group A: 9 patients; median age 8.6 [1.6-16.7] years; group B: 14 patients; median age 8.5 [1.9-14.6] years). The median follow-up was 88 (14-112) and 22 (4-109) months. Both groups were transplanted with comparable organs. Eight (8/9) and six (6/14) patients received preoperative renal support in each group, respectively, whereas an equal proportion of them required early postoperative renal support (4/8; 50% and 3/6; 50%, respectively). Glomerular function was significantly different between groups until first year posttransplant (median estimated glomerular filtration rate: groups A vs. B; at pretransplant, 3 mo, 6 mo, and 12 mo posttransplant, respectively; 11.06 vs. 12.61 [P=0.4], 40.78 vs. 75.83 [P=0.03], 42.59 vs. 80.56 [P=0.04] and 53.57 vs. 76.75 [P=0.005]). Overall 1-year survival is 89% versus 90% and 5-year survival is 89% versus 62%, respectively. Summary: Children with PH-I receiving CLKT seem to have delayed recovery of renal function compared with polycystic disease, possibly due to mobilization of systemic oxalate. Consideration should be given to earlier or preemptive transplantation for children with PH-I. https://pubmed.ncbi.nlm.nih.gov/19461498/?from_term=david+a+mayer&from_size=200&from_pos=7 Improved outcomes of combined liver and kidney transplants in small children (<15 kg). Perera MT, Silva MA, Sharif K, McKiernan PJ, Kelly DA, Lloyd C, Milford DV, Mayer DA, Mirza DF. Transplantation. 2009 Sep 15;88(5):711-5. doi: 10.1097/TP.0b013e3181b29f0c.PMID: 19741470 Abstract Background: Combined liver and kidney transplantation (CLKT) is a surgical challenge in small children because of technical aspects, lack of pediatric donors, and restrictions related to the size of the abdominal cavity. We report outcomes after CLKT in this challenging group of smaller children. Method: A review of prospective data on all children undergoing CLKT at the Birmingham Children's Hospital between 1994 and 2008 was performed. An analysis of perioperative data, complications, and survival in children less than 15 kg was carried out, with figures expressed as median (range) and compared with that of children more than 15 kg. Results: A total of 23 children underwent CLKT (14 male [61%] and age 8.6 [1.6-16.7] years), of which 8 (35%) were less than or equal to 15 kg, median age 2.2 (1.6-5.4) years, weight 11.6 (9.1-14.9) kg, and height 76 (66-95) cm, followed up for a median 26 (12-126) months. Donor details included age 13 (3-40) years, weight 60 (15-78) kg, and height 156 (83-168) cm. The median donor-to-recipient weight ratio was 4.8 compared with 1.7 for larger children. The median waiting time was 291 (48-523) compared with 150 (6-455) days for children more than 15 kg. Four of eight (50%) children received preoperative renal support, when compared with 10 of 16 (62%) children more than 15 kg. The intensive care unit and inpatient stay was 2 (2-22) days and 25 (19-93) days, respectively. Mortality was seen in one of eight because of sepsis and multiorgan failure. When compared with children more than 15 kg, survival figures at 1 and 2 years were 87% versus 93% and 78%, respectively. Conclusions: CLKT in small children results in comparable outcomes despite challenges related to donor-recipient size mismatch and longer waiting times. Consequently, body size/stature should not be a limiting factor for multiorgan transplantation. https://pubmed.ncbi.nlm.nih.gov/19741470/?from_term=david+a+mayer&from_size=200&from_pos=8

67

ABO-incompatible pediatric liver transplantation in very small recipients: Birmingham's experience. Gelas T, McKiernan PJ, Kelly DA, Mayer DA, Mirza DF, Sharif K.Pediatr Transplant. 2011 Nov;15(7):706-11. doi: 10.1111/j.1399-3046.2011.01541.x. Epub 2011 Jul 15.PMID: 21762327 Abstract Liver transplantation (LT) for very small recipients is challenging but in experienced centres, good results can be achieved. Despite the risk of antibody-mediated acute rejection, some studies have demonstrated the safety of ABO incompatible liver transplantation (ILT) in children and particularly in infants. The aim of our study was to describe the outcome of liver transplantation in infants <5 kg and the safety of using ILT in this group. All LT performed between 1991 and 2010 in children <5 kg were reviewed. Twenty-nine patients were included, five of whom had an ILT. Acute liver failure was encountered in 20 cases. The recipient age and weight at transplantation were respectively 63 days (range: 14-268 days) and 4 kg (range: 2.4-5 kg). The graft-to-recipient ratio was 6.1% (range 2.3-9%). An aortic conduit and delayed abdominal closure were used respectively in 76% and 81% of the procedures. The ABO compatible liver transplantation (CLT) and ILT groups were similar regarding recipient's demographics, graft types or technical transplantation data. The one- and five-yr patient and graft survival were respectively 62%, 62% and 62%, 57.9% with a median follow-up of 95 months. Vascular complications occurred in six cases (21.4%) and biliary complications were encountered in five patients (17%). Acute and chronic rejection developed respectively in 37% and 26% of the recipients. The five patients undergoing ILT are all alive without graft lost after a median follow-up of 34 months (range 7-55 months). When compared with the CLT group, no significant differences were found regarding patient or graft survival, vascular or biliary complications and rejection rates. In our experience, ILT in small infants has short and long term outcomes comparable to ABO-compatible grafts and excellent results can be achieved with a standard immunosuppressive protocol. To avoid mortality on the waiting list for neonatal recipients, ABO-incompatible liver grafts can be used safely. https://pubmed.ncbi.nlm.nih.gov/21762327/?from_term=david+a+mayer&from_size=200&from_pos=9 Corticosteroid-free immunosuppression with tacrolimus following induction with daclizumab: a large randomized clinical study. Boillot O, Mayer DA, Boudjema K, Salizzoni M, Gridelli B, Filipponi F, Trunecka P, Krawczyk M, Clavien PA, Ducerf C, Margarit C, Margreiter R, Pallardo JM, Hoeckerstedt K, Pageaux GP. Liver Transpl. 2005 Jan;11(1):61-7. doi: 10.1002/lt.20307.PMID: 15690537 Free article. Clinical Trial. Abstract This open, randomized (1 : 1), multicenter, 3-month study compared a dual tacrolimus plus steroids (Tac / steroids) regimen with a steroid-free immunosuppressive regimen of tacrolimus following daclizumab induction therapy (Tac / Dac) in adult liver transplant recipients. The full analysis set comprised 347 patients in the Tac / steroids group and 351 in the Tac / Dac group. Mean tacrolimus dose during month 3 was 0.11 mg/kg/day in both groups; mean whole-blood trough levels during month 3 were 10.9 ng/mL (Tac / steroids) and 10.6 ng/mL (Tac / Dac). The incidence of biopsy-confirmed acute rejection that required treatment was similar in both groups: 26.5% in the Tac / steroids group and 25.4% in the Tac / Dac group (P = .727). However, the incidence of biopsy-confirmed corticosteroid-resistant acute rejection was higher in the Tac / steroids group than in the Tac / Dac group (6.3 vs. 2.8%; P = .027). Kaplan-Meier estimates of graft survival (92.2 vs. 90.5%) and patient survival (94.5 vs. 93.7%) were similar in both groups. While also the overall adverse event profiles were similar, the incidences of diabetes mellitus (15.3 vs. 5.7%, respectively; P < .001) and cytomegalovirus infection (11.5 vs. 5.1%, respectively; P = .002) were higher in the Tac / steroids group compared with the Tac / Dac group. Mean cholesterol levels increased by 16% in the Tac / steroids group, but were unchanged in the Tac / Dac group during the study. In conclusion, tacrolimus monotherapy following daclizumab induction is an effective and safe regimen, with an advantage over concomitant steroid-maintenance therapy in terms of a lower incidence of diabetes and viral infection, and a lower incidence of steroid-resistant acute rejection. https://pubmed.ncbi.nlm.nih.gov/15690537/?from_term=david+a+mayer&from_size=200&from_pos=10

68

Application of Portsmouth modification of physiological and operative severity scoring system for enumeration of morbidity and mortality (P-POSSUM) in pancreatic surgery. Tamijmarane A, Bhati CS, Mirza DF, Bramhall SR, Mayer DA, Wigmore SJ, Buckels JA. World J Surg Oncol. 2008 Apr 9;6:39. doi: 10.1186/1477-7819-6-39.PMID: 18400108 Free PMC article. Abstract Background: Pancreatoduodenectomy (PD) is associated with high incidence of morbidity and mortality. We have applied P-POSSUM in predicting the incidence of outcome after PD to identify those who are at the highest risk of developing complications. Method: A prospective database of 241 consecutive patients who had PD from January 2002 to September 2005 was retrospectively updated and analysed. P-POSSUM score was calculated for each patient and correlated with observed morbidity and mortality. Results: 30 days mortality was 7.8% and morbidity was 44.8%. Mean physiological score was 16.07 +/- 3.30. Mean operative score was 13.67 +/- 3.42. Mean operative score rose to 20.28 +/- 2.52 for the complex major operation (p < 0.001) with 2 fold increase in morbidity and 3.5 fold increase in mortality. For groups of patients with a physiological score of (less than or equal to) 18, the O:P (observed to Predicted) morbidity ratio was 1.3-1.4 and, with a physiological score of >18, the O:P ratio was nearer to 1. Physiological score and white cell count were significant in a multivariate model. Conclusion: P-POSSUM underestimated the mortality rate. While P-POSSUM analysis gave a truer prediction of morbidity, underestimation of morbidity and potential for systematic inaccuracy in prediction of complications at lower risk levels is a significant issue for pancreatic surgery. https://pubmed.ncbi.nlm.nih.gov/18400108/?from_term=david+a+mayer&from_size=200&from_pos=11 Ex situ preparation of left split-liver grafts with left vascular pedicle only: is it safe? A comparative single-center study. Noujaim HM, Gunson B, Mirza DF, Mayer DA, Candinas D, Buckels JA, McMaster P, de Ville de Goyet J. Transplantation. 2002 Nov 27;74(10):1386-90. doi: 10.1097/00007890-200211270-00007.PMID: 12451236 Abstract The procurement of left-lateral-segment grafts from living donors for transplantation in children is performed by retaining only the left branches of the artery and veins. New techniques and the implementation of microsurgery in the transplant operation made this procedure a successful approach. However, controversy persists about using such an approach for division of liver grafts from cadaveric donors, and many teams prefer retaining the main arterial trunk with the left split graft, with or without the main portal vein trunk. Since 1998, in our center, when a donor-liver graft is divided we prefer retaining the main vessels with the right split graft if graft vascular anatomy is favorable. After 1998, 40 liver grafts from cadaveric donors were divided, and all divisions were performed ex situ. This experience was retrospectively reviewed to compare the outcome of left split grafts prepared for implantation with the left vasculature only (group A), or with the main arterial supply (group B). A single vascular complication occurred (one hepatic artery thrombosis in group B). Three patients died (one in group A and two in group B) and three other grafts were lost (one in group A and two in group B). One-year and 3-year graft survival rates were 94% and 86% in group A, and 83% and 83% in group B, respectively (not significantly [NS] different). We conclude that left split grafts can be safely transplanted with the left vascular supply only, provided that division is guided by careful anatomical evaluation and that vascular reconstructions are adequate. https://pubmed.ncbi.nlm.nih.gov/12451236/?from_term=david+a+mayer&from_size=200&from_pos=12

69

Surgical complications after intestinal transplantation in infants and children--UK experience. Gupte GL, Haghighi KS, Sharif K, Mayer DA, Beath SV, Kelly DA, Buckels J, de Goyet Jd, Mirza DF, Millar AJ.J Pediatr Surg. 2010 Jul;45(7):1473-8. doi: 10.1016/j.jpedsurg.2009.08.026.PMID: 20638527 Abstract Surgical complications have a significant impact on morbidity and mortality following intestinal transplantation (ITx). Birmingham Children's Hospital commenced intestinal transplantation in 1993 and the following surgical strategies evolved: (a) pretransplant abdominal tissue expanders, 1998; (b) combined en-bloc reduced liver and intestinal transplantation (CRLITx), 1998; (c) staged abdominal closure, 2001; (d) preservation of graft duodenal artery, 2005. Aim: An internal audit was performed to document the surgical complications after ITx and to evaluate strategies in the management and prevention of complications. Methods: A retrospective analysis of the medical records from January 1993 to June 2007 was conducted to identify surgical complications, evaluate management strategies, and report outcome following ITx. Results: Forty-six children underwent 49 ITx (9 isolated intestinal, 39 combined liver and intestinal [CLITx], and 1 multivisceral transplant). Twenty three children had CRLITx since 1998, although there were none before 1997. The median donor: recipient weight ratio in CLITx was 2.2:1 (range, 0.67:1-6.70:1). Twenty-six children experienced 29 (59%) surgical complications: portacaval shunt thrombosis (n = 2, none alive); graft duodenal stump leakage (n = 3, 2 alive); spontaneous bowel perforation(n = 6, 2 alive); sub-acute bowel obstruction (n = 6, all alive); abdominal compartment syndrome ([ACS], n = 4, 2 alive); pancreatic leak (n = 3, 2 alive); biliary complications (n = 22, 17 alive ) failed staged abdominal closure with wound sepsis requiring skin grafting into the bowel (n = 1, alive), wound dehiscence (n = 1, alive), anastomotic leak (n = 1, alive) and intra-abdominal bleeding (n = 1,alive), primary nonfunction (n = 1, 1 died). Following the complications of ACS in children with primary abdominal closure and graft duodenal stump leaks in 2004, we modified our strategies in 2005 to include staged abdominal closure with recipient to donor weight mismatch, and preservation of the gastroduodenal artery during donor organ procurement in addition to pre transplant abdominal tissue expansion. Fifteen children with recipient and donor weight mismatch subsequently required staged closure of the abdomen and none of them developed ACS. Twelve children had gastroduodenal artery preserved and none developed graft duodenal stump leaks. Twenty-four of the 46 (52%) are alive 6 months to 10 years post transplant. Conclusion: Evolving strategies may avoid or reduce surgical complications commonly seen after intestinal transplantation and thus contribute to an improved outcome. Copyright 2010 Elsevier Inc. All rights reserved. https://pubmed.ncbi.nlm.nih.gov/20638527/?from_term=david+a+mayer&from_size=200&from_pos=13 Worth continuing doing ex situ liver graft splitting? A single-center analysis. Noujaim HM, Gunson B, Mayer DA, Mirza DF, Buckels JA, Candinas D, McMaster P, de Ville de Goyet J.Am J Transplant. 2003 Mar;3(3):318-23. doi: 10.1034/j.1600-6143.2003.00047.x.PMID: 12614288 Abstract Grafts for split liver transplantation can be prepared in situ during the retrieval operation, or ex situ on the back table. The in situ technique has theoretical advantages because it minimizes the cold ischemic time and allows excellent hemostasis at the cut surface. However, in situ liver division prolongs the retrieval procedure, may precipitate hemodynamic instability in the donor, and may cause logistical difficulties for some centers. This report is a single-center analysis comparing results of ex situ liver division (group I: 1992-97; and group II: 1998-2001) before and after a new protocol for liver graft division was introduced in our center. Eighty-nine split liver transplants (SLT) were reviewed increased from 59% to 78% (p = 0.03). Since 1998, 1-year graft survival of SLT has been similar to that of conventional liver graft transplantation in our center (78% and 74%, respectively). In conclusion, good results can be achieved from splitting livers ex situ and this procedure should be considered when the in situ technique is not feasible. https://pubmed.ncbi.nlm.nih.gov/12614288/?from_term=david+a+mayer&from_size=200&from_pos=14

70

A reaudit of specialist-managed liver trauma after establishment of regional referral and management guidelines. Ramkumar K, Perera MT, Marudanayagam R, Coldham C, Olliff SP, Mayer DA, Bramhall SR, Buckels JA, Mirza DF.J Trauma. 2010 Jan;68(1):84-9. doi: 10.1097/TA.0b013e3181bdd1ee.PMID: 20065762 Abstract Background: An earlier liver trauma audit (52 patients) noted that 50% were surgically managed at referring hospitals with a high morbidity and mortality, after which a regional referral and management algorithm was implemented in 2001. This study aims to reaudit specialist-managed liver trauma outcomes. Methods: Prospective analysis of 99 patients (68 male) treated for liver injury (LI) between 2001 and 2008. Patient characteristics, management, and outcome results of these were compared with the results of previous audit. LI severity was determined by computed tomography, operative findings, and classified according to liver Organ Injury Scale. Results: As implementation of guidelines, referrals increased from 5.2 patients/yr to 14.1 patients/yr, while LI profile was unchanged. Fewer patients were managed surgically with lower surgical intervention at referring hospitals (26 of 52 [50%] vs. 29 of 77 [38%]; p = 0.2). There has been a decrease in liver resection rates (14 of 26 [54%] vs. 3 of 37 [8%]; p = 0.0001]), overall mortality rate (12 of 52 [23%] vs. 11 of 99 [11%]; p = 0.059), and postoperative deaths. Conclusion: This reaudit confirms the role of nonoperative management of liver trauma. Early use of computed tomography scan with specialist discussion, selective use of perihepatic packing, and transfer to a specialist unit should be standard practice in the management of complex liver trauma. https://pubmed.ncbi.nlm.nih.gov/20065762/?from_term=david+a+mayer&from_size=200&from_pos=15 Impact of change in the United Kingdom pediatric donor organ allocation policy for intestinal transplantation. Giovanelli M, Gupte GL, McKiernan P, Pocock P, Beath SV, Lloyd C, Sharif K, Mayer DA, Mirza DF. Transplantation. 2009 Jun 15;87(11):1695-9. doi: 10.1097/TP.0b013e3181a5e9f8. Abstract Background: Graft availability remains a problem in pediatric intestinal transplantation (IT), with most children waiting being less than 10 kg weight. In November 2004, wait-listed children in the United Kingdom were prioritized nationally to receive pediatric donor organs to improve donor availability for IT. We aimed to evaluate the impact of this change on the recipient population. Methods: Data regarding pediatric donor organ availability and allocation were accessed from the National Transplant database. Recipient demographics and outcomes were recorded from the Liver Unit database. Between 2001 and 2006, there were 228 pediatric donors in the United Kingdom (nonheart-beating donors were excluded), of which 39 livers were allocated to emergency super-urgent liver candidates. A total of six isolated intestine and 21 liver-intestine transplants (15 reduced size, six full grafts) were performed in the same period. Results: Since January 2001, there has been a progressive reduction in overall pediatric organ donation. Increasing awareness about IT has resulted in a significant increase in number of small bowel organs being offered (71.8% vs. number of IT being performed (2.6 vs. 7.7 mean transplants per year), waiting list mortality still remains high in smaller children (<10 kg weight). No mortality was observed in larger children and in candidates for isolated IT. Conclusions: The new prioritization of the national pediatric donor allocation favoring IT has resulted in an increased number of procedures, without an impact on waiting list mortality for small children. https://pubmed.ncbi.nlm.nih.gov/19502962/?from_term=david+a+mayer&from_size=200&from_pos=16

71

Outcomes after identical and compatible orthotopic liver transplantation for fulminant hepatic failure: a single center experience in UK. Koukoutsis I, Bellagamba R, Tamijmarane A, Gunson B, Muralidharan V, Wigmore SJ, Mayer DA, Mirza DF, Buckels JA, Bramhall SR. Transpl Int. 2007 Aug;20(8):659-65. doi: 10.1111/j.1432-2277.2007.00458.x. Epub 2007 Mar 1. Abstract To analyze the outcomes between identical and compatible liver transplantation (OLT) for fulminant hepatic failure (FHF) from September 1984 to November 2005. The patients were divided in three groups; group 1 (identical), group 2 (compatible) and group 3 (incompatible), according to the donor-recipient blood type matching. We analyzed several outcomes regarding mortality, patient and graft survival, incidence of acute graft rejection during the first postoperative month (30 days), incidence of biliary complications and indications of re-transplantation. We also analyzed the relationship of Coomb's positive test with postoperative hemolysis to all the above mentioned factors. During the study period, 168 males and 112 females underwent their first OLT for FHF, with 37.1% overall mortality and 42.1% overall graft failure rate. The results between group 1 (203 patients) and group 2 (73 patients) were comparable. A statistically significant difference was recorded in 1 year and overall graft survival between group 1 and group 2 (P = 0.049 and log-rank = 0.035 respectively). Coomb's positive test did not influence the outcomes. OLT in FHF can be safely carried out whether the donor organs are identical or compatible. Hemolysis (Coomb's positive test) after identical or compatible OLT does not influence the outcomes. https://pubmed.ncbi.nlm.nih.gov/17343687/?from_term=david+a+mayer&from_size=200&from_pos=17 Catheter-directed tissue plasminogen activator infusion and concurrent systemic anticoagulation with heparin to treat portal vein thrombosis post orthoptic liver transplantation. Gill P, Oniscu GC, Mayer DA, Mirza DF, Olliff S. Transplantation. 2009 Aug 27;88(4):595-6. No abstract available