Samidirect business-manual

16
Healthy, Wealthy & Wise Healthy, Wealthy & Wise No. 30 & 31, 5th Cross,5th Block, Koramangala, Bangalore - 560034, Karnataka, India. Tel: 91 80 4038 1800 Fax: 91 80 4038 1838 [email protected] www.samidirect.com .. .. .. ... ...... ... .. . .. ... . ...... ...... ..... ..... ...... ...... .. .. . ..... ..... ..... ..... ......... ......... ......... ......... ......... ......... ... ... ... ... ..... ..... ..... ... ... ... ... .... .... .... .. .. .. .. .. .. .. ..... ..... ..... ..... .... .... .... ... .. .. .. .. .. .. .. .. .. .. . . .. .. .. .. .. .. .. ........ ........ ........ ........ ........ ........ ........ ........ ... ... ... ... .... .... .... ... ... ... ... .... .... .... .... .... .... .... .... .... ...................... ................................................... ..................................................... ..................................................... ..................................................... ..................................................... ..................................................... ..................................................... 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Sami Labs Worldwide Sami Labs Worldwide Sami Labs Worldwide

description

Over 20 years we have been unlocking the mystery of the herbs, extracting the goodness, gifting the world with Good health Now we provide you an opportunity to unlock the mystery of Success, Wealth & Better living Sami Direct is the culmination of relentless Research and development for more than 2 decades. We at Sami Direct are committed to offer you an unrivalled range of Nutraceutical followed by cosmeceutical products which has been acknowledged by the world over for its highest quality and safety standards. Sami Direct is supported by its very own indigenous R&D facility - SAMI LABS at Bangalore, A State-of-the-Art multi-disciplinary division pursing diverse fields of research with over 120 Scientists which focuses its efforts towards creating effective and safe products . The six highly advanced, state-of-the-art manufacturing units, which adhere to the strictest quality and safety norms ensures the highest quality of products are being rolled out. Today, Sami Group holds a strong intellectual property portfolio with several US and International Patents to its credit apart from awards and recognitions worldwide. With the perfect blend of world class products and a revolutionary business plan, for you it is a lifetime opportunity not just to enhance your health, but a fruitful and lasting career which would heighten your income.

Transcript of Samidirect business-manual

Page 1: Samidirect business-manual

Healthy, Wealthy & Wise

Healthy, Wealthy & Wise

No. 30 & 31, 5th Cross,5th Block,Koramangala, Bangalore - 560034,Karnataka, India.

Tel: 91 80 4038 1800Fax: 91 80 4038 1838 [email protected]

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Sami Labs WorldwideSami Labs WorldwideSami Labs Worldwide

Page 2: Samidirect business-manual

Dr. Muhammed Majeed is the inspiration and motivation

behind Sami and the Sabinsa Group of Companies. Dr. Majeed

has a Ph.D in Industrial Pharmacy. After a decade and half of

working with respected names in the American pharmaceutical

industry, Dr. Majeed first set up Sabinsa Corporation in New

Jersey, USA in 1988. He later set up Sami Labs Limited Bangalore,

India in 1991, with the vision of research, development and

marketing of a new genre of products – natural therapeutics.

Over the past two decades, the organization has grown into a

health science multinational with presence in USA, Europe,

India, Japan, Australia, China, UAE, South Africa and Brazil. It

employs over a 1000 people with four manufacturing locations

in India and one in USA. Its research facility in Bangalore has

over a hundred scientists involved in specialized work in the

areas of phytochemistry, organic chemistry, biochemistry,

tissue culture and plant biotechnology.

Today, Sami holds a strong intellectual property portfolio with

several US and international patents to its credit apart from

awards and recognitions worldwide.

Founder speaksFounder speaksFounder speaks

Dr. Muhammed Majeed

““

Dear Friend, Congratulations on your decision!

A little over 3 decades ago, I went from a small town of South India to the United States of America seeking fulfillment of my dreams. Today, with a business conglomerate spread across the world, I can confidently say that the future belongs to those who believe in the beauty of their dreams.

The aspiration to dream and the conviction to follow their dreams is what sets apart the extraordinary from the ordinary. Congratulations for choosing to be among the extraordinary.

Now we are in it together. You have chosen the right place and the right means. The awesome combination of extensively researched products and a revolutionary business plan is a definite formula for success. Believe me, making money has never been such fun !

We are with you at every step to help you fulfill your dreams and reach greater heights.

Welcome again,

Dr. Muhammed Majeed

Page 3: Samidirect business-manual

In Nature lies the power… to heal and to protect. A truth

that our ancestors had known and practiced centuries ago

has only now come to the understanding of the modern

generation. Sami was born out of this realization, and exists

for the sole purpose of bringing the healing power of

Nature to cure and nurture human life.

The miraculous properties of nature can be fully extracted

only through innovative use of scientific technology. Thus,

based on market-oriented research, the company

integrates modern scientific techniques with ancient

wisdom of Ayurvedic herbal armamentariums to produce

new drug molecules – health solutions that have brought

back smiles to millions of faces around the world.

As one of the world's largest health science company, the

Sami Group has a responsibility towards the people.

Through innovative research, deep understanding of the

market and production excellence, Sami Labs Ltd. will

provide consumers with the best of natural product

solutions for a healthier and wealthier life

Where innovation is a tradition

From the desk of the CEOFrom the desk of the CEOFrom the desk of the CEO

Mr. Rajesh Kumar, CEO

Welcome on board Sami Direct. As we embark on this journey of fulfilling the dreams of our Business Associates by bringing nutrition to everyday life , we are glad to have you with us.

Sami Direct is the culmination of relentless Research and development for over 22 years. We at Sami Direct are committed to offer you an unrivalled range of Nutraceutical followed by cosmeceutical products which has been acknowledged by the world over for its highest quality and safety standards.

With the perfect blend of world class products and a revolutionary business plan, for you it is a lifetime opportunity not just to enhance your health, but a fruitful and lasting career which would heighten your income.

Your journey as an independent Entrepreneur will be supported by extensive training programmes by the masters themselves as a step by step guide in realizing and fulfilling your dreams, and to top it all recognition and rewards for every milestone that you reach.

Our team of professionals with proven experience in the industry whose constant endeavour will be to offer solutions which are most beneficial to its distributors & customers. A thousand mile journey starts with the single step, and I am confident that you have taken the right step.

I wish you great success and great health.

Once again I welcome you on board.

Yours Truly,

Rajesh Kumar

Page 4: Samidirect business-manual

Our facilitiesOur facilitiesOur facilities

Solid foundation for our dreams

Sami Labs has created a benchmark for standardized herbal medicines

globally. With six highly advanced, state-of-the-art manufacturing units,

which adhere to the strictest quality and safety norms, Sami Labs focuses

all its efforts towards creating effective and safe products.

Every facility is in compliance with rules and regulations. All effluent

streams are treated and disposed off significantly. Reflecting the internal

system of quality and regulatory requirements, the facilities are certified

by National Sanitary Foundation of USA and the Orthodox Union (Kosher)

of USA.

Its Good Manufacturing Practices (GMP) registration is just one of the

many aspects that reflect the company’s commitment to high quality

products.

Sami Labs, Bangalore, India

Manufacturing facility, Kunigal

Biotechnology Facility, Nelamangala

Manufacturing Facility, Hyderabad

Super Critical Fluid Extraction , NelamangalaFacility

Continuous Extraction Unit, Dobaspet

Sabinsa Utah, USAManufacturing,

Page 5: Samidirect business-manual

Research & DevelopmentResearch & DevelopmentResearch & Development

Finding new light

Recognized by the Department of Scientific and Industrial Research, Sami

R&D is a multi-disciplinary division pursuing diverse fields of research.

The R&D also works closely with the Government of India and the Indian

Pharmacopoeia Committee on preparation of Standard Operating

Procedures for Ayurvedic herbs and monographs for Indian herbs.

Equipped with the best of talent and facilities, Sami research is geared to

constantly innovate and sustain high quality output to broaden the

product portfolio, enrich its intellectual property and build up a robust

pipeline of products.

Natural Drug Division:

Phytochemistry:

Synthetic Chemistry :

This division focuses on identifying, isolating and developing drugs from various natural source having a potential to become a drug.

This division does the isolation and development of active ingredients from herbs for various nutraceutical and therapeutic applications.

Sami Labs has set up a strong synthetic chemistry division to manufacture some of the synthetically derived nutraceuticals. This division currently works on:

Development of drug and drug intermediates

Development of selenium amino acid

Development of chiral molecules

Development of peptides for cosmeceuticals

Method development

Validation

Development of specification for all products and

Quality control & Quality Assurance

Biological Research:

This department tests the safety and efficacy of the products developed in the R&D i.e. cosmeceuticals and nutraceutical products. They have developed several in vitro models for testing anti-obesity, anti-diabetic, anti-ageing and several other disease conditions. Non-animal toxicity testing is also undertaken.

It is a key function in the R&D and it supports all the development activities.

Their important roles are:

This department develops natural cosmetic products that have properties to rejuvenate and protect the skin from environmental pollution, toxic chemicals and Ultraviolet A and B radiation resulting in wrinkling, hyper pigmentation (excessive tanning) and inflammations (sunburn). The department also develops dosage formulations in capsules, tablets etc for the nutraceutical products.

Sami Labs ventured into Biotechnology in the year 2000. LactoSpore® is the first commercial production using the in-house R&D technology. This division is currently involved in the production of high-value enzymes as well as other probiotics .

The scientists here develop high-yielding varieties of medicinal plants & multiply them through tissue culture techniques in the laboratory.

Analytical R&D:

Formulations R&D:

Biotechnology:

Tissue Culture:

Page 6: Samidirect business-manual

Intellectual PropertiesIntellectual

Properties Intellectual

Properties

63 International patents and still growingWe have 63 patents to our credit, as on September 2010.

US PATENTS

Title No Brand /IngredientPatent

Title No Brand /IngredientPatent

01.

02.

03.

04.

05.

06.

07.

08.

09.

10.

11.

12.

13.

14.

15.

16.

17.

18.

19.

20.

21.

22.

23.

24.

25.

26.

27.

28.

29.

30.

US 5,536,506

US 5,744,161

US 5,783,603

US 5,804,596

US 5,861,415

US 5,972,382

US 6,054,585

US 6,436,991

US 6,607,712

US 6,653,327

US 6,689,400

US 6,770,782

US 6,794,537

US 6,849,645

US 6,960,300

US 6,982,273

US 6,998,502

US 7,345,196

US 7,014,874

US 7,063,861

US 7,160,562

US 7,202,270

US 7,217,546

US 7,253,324

US 7,300,682

US 7,371,889

US 7,378,442

US 7,514,573

US 7521580

US 7582314

BioPerine®

BioPerine®

Citrin®K

ForsLean®

3Curcumin C Complex®

BioPerine®

BioPerine®

Gugulipid®

Coleus Oil

Tetrahydrocurcuminoids

ZeaLutein®

Citrin® K

Methyselene

Cosmoperine®(THP)

Forskolin Eye Drops

Methyselene®

Efflornithine

Efflornithine

SelenoForce®

GarCitrin®

Metformin-Like Compounds

Liposol

Policosanol

Stilbenes

Cococin™

AKBBA+NSAIDS

AKBBA+NSAIDS

3-Aminotetrahydrofurans

3Curcumin C Complex

®

Use of Piperine to increase bioavailability of nutritional compounds

Use of Piperine as a bioavailability enhancer

Potassium hydroxycitrate for the suppression of appetite and induction of weight loss

Novel Method of preparing a Forskolin composition from Forskolin extract and use of Forskolin for promoting lean body mass and treating mood disorders

Bioprotectant composition, method of use and extraction process of Curcuminoids

Use of Piperine as a bioavailability enhancer

Process for making high purity piperine for nutritional use

Composition and method containing products extracted from Commiphora Sp. for prevention and treatment of abnormal cell growth and proliferation in inflammation, neoplasia and cardiovascular disease

Composition and methods containing an antimicrobial essential oil extracted from Coleus Forskohlii.

Cross regulin composition of turmeric-derived Tetrahydrocurcuminoids for skin lightening and protection against UVB rays

Process of obtaining composition of stable lutein and lutein derivatives

Process for the production of potassium hydroxy citric acid and compositions containing the potassium hydroxy citric acid

Manufacturing Processes for Se-alkylselenocysteine, Se-allylselenocysteine, Se-arylselenocysteine

Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives

Process for preparing water soluble diterpenes and their applications.

Composition and methods containing bioavailable Se-methyl-L-Selenochysteine for human and veterinary.

A Convenient Process of Manufacture For Difluromethylornithine And Related Compounds

A Convenient Process of Manufacture For Difluromethylornithine And Related Compounds

Compositions and Methods containing Allium Sativum Linn, (Garlic) naturally enriched with organic selenium compounds for nutritional supplementation

Bioavailable compositions of Natural and Synthetic HCA

Compositions and methods containing natural compounds from non-conventional sources that are useful in maintaining normal blood sugar levels

Convenient stable non-hygroscopic crystalline solid forms of racemic and chiral LA-plus salts process for their manufacture and uses

Commercially viable process for high purity of fatty alcohol C24 to C36 and its cosmetic application for skin hair and nails

Process for the synthesis of biologically active oxygenated compounds by dealkylation of the corresponding alkylethers

Method of preparation and use of coconut water in mammalian tissue nourishment, growth, and healthy maintenance

New Chemical entities with multiple modes of anti-inflammatory action

New Chemical entities with multiple modes of anti-inflammatory action

Process for the Manufacture of Chiral And Racemic Forms of 3-Aminotetrahydrofurans, their Salts and Derivatives

Non-cytotoxic synthetic analogues of (1E, 6E )-1,7-Bis (4 hydroxy-3-methoxyphenyl)-1,6-heptadiene-3, 5-dione and therapeutic applications thereof in cystic fibrosis)

Composition and methods for the management of hyperproliferative dermatological conditions

Page 7: Samidirect business-manual

INTERNATIONAL PATENTS

Title No Brand /IngredientPatent

Title No Brand /IngredientPatent

01.

02.

03.

04.

05.

06.

07.

08.

09.

10.

11.

12.

13.

14.

15.

16.

17.

18.

19.

20.

21.

22.

23.

24.

25.

26.

27.

28.

29.

30.

31.

32.

33.

AU2006235807

AU773081

CA2247467

CA2281562

EP0810868

EP0839037

EP0977564

EP1171144

EP1254209

EP1341547

EP1328263

GB2380675

IN229695

IN235492

IN238950

JP3953513

JP4098985

JP4205943

JP4227409

MX260326

NZ514884

NZ518116

NZ552027

NZ552997

NZ545765

NZ568652

PH/12006500481

RU12836

RU2366412

SG121197

SG136165

ZA2006/01898

ZA2007/0694

Tetrahydrocurcuminoids

GarCitrin®

BioPerine®

ForsLean®

BioPerine®

3Curcumin C Complex®

ForsLean®

Tetrahydrocurcuminoids

GarCitrin®

Cococin™

Tetrahydrocurcuminoids

Cosmoperine®(THP)

Policosanol

Forskolin Eye Drops

BioPerine®

Cosmoperine®(THP)

GarCitrin®

ZeaLutein®

Forskolin Eye Drops

Tetrahydrocurcuminoids

GarCitrin®

Forskolin

Forskolin Eye Drops

Forskolin-Div1

Forskolin Eye Drops

Forskolin Eye Drops

Forskolin Eye Drops

Forskolin Eye Drops

Use of Tetrahydrocurcuminoids to Regulate Physiological and Pathological Events in the Skin and Mucosa

Bioavailable compositions of Natural and Synthetic HCA

Use of Piperine as a Bioavailability Enhancer

Forskolin for promoting Lean Body Mass

Use of Piperine as a bioavailability enhancer

Bioprotectant composition, method of use and extraction process of Curcuminoids

Forskolin For Promoting Lean Body Mass

Use of Tetrahydrocurcuminoids to Regulate Physiological and Pathological Events in the Skin and Mucosa

Bioavailable compositions of Natural and Synthetic HCA

Coconut water and its method of preparation

Process of making and method of use of tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa cells

Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives

A process for obtaining high purity fatty alcohols

A method for solubilizing forskolin and a composition thereof

A Process of preparing a synergistic composition for treating hyperproliferative dermatological conditions.

Use of Piperine as a Bioavailability Enhancer

Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives

Bioavailable compositions of Natural and Synthetic HCA

Process of obtaining composition of stable lutein and lutein derivatives

Process of preparing water soluble diterpenes and their applications

Use of tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa

Bioavailable compositions of Natural and Synthetic HCA

Compositions and methods for the management of hyperproliferative dermatological conditions

Composition for physiological increase of male and female hormones with diterpene forskolin and its derivatives

Process For Preparing Water Soluble Diterpenes And Their Applications

Commercial Process for Making Forskolin and its Derivatives

Process for preparing water soluble diterpenes and their applications

Process for Preparing Water Soluble Diterpenes and Their Applications

Compositions and methods for the management of hyperproliferative dermatological conditions

Process of preparing water soluble diterpenes and their applications

Compositions and methods for the management of hyperproliferative dermatological conditions

Process for preparing water soluble diterpenes and their applications

Composition and methods for the management of hyperproliferative dermatological Conditions.

AU-Australia

CA-Canada

EP-Europe

GB-Great Britain

IN-India

JP-Japan

MX-Mexico

NZ-New Zealand

PH-Philippines

RU-Russia

SG-Singapore

US-United States

ZA-South Africa

Intellectual PropertiesIntellectual

Properties Intellectual

Properties

Page 8: Samidirect business-manual

Recognition Recognition Recognition The proof of excellence

1994: Dr. Majeed receiving the National Award for Quality and Innovation (Basic Drugs) from (Late) Dr. Shankar Dayal Sharma, President of India.

2008: Dr. Majeed receiving the Certificate of Excellence for Exports from Federation of Indian Export Organisations.

2006-07: Dr. Majeed receiving the Export Excellence Award from Federation of Karnataka Chamber of Commerce & Industry.

2002: Dr. Majeed receives DSIR Award for R&D efforts in the category of "Chemical and Allied Industries"

1996-97: Dr. Majeed receiving the National Award from (Late) Dr. Shankar Dayal Sharma, President of India, awarded by Spice Board.

2009: Sabinsa Received Thomas Alva Edison Patent Award for GarCitrin from Research & Development Council of New Jersey , USA

2004: Sabinsa Received Thomas Alva Edison Patent Award for ForsLean from Research & Development Council of New Jersey , USA

1998-99: Certificate of Honour for Outstanding Performance in the Export of Spices/Spice Products from India issued by Spices Board.

2005: Sabinsa Received Thomas Alva Edison Patent Award for Tetrahydropiperine from Research & Development Council of New Jersey , USA

2008: Export Excellence Award.

2008: Certificate of Excellence for Export Achievement from the Ministry of Commerce, Government of India being received by Mr. K.B. Siva Prakash.

Page 9: Samidirect business-manual

Recognition Recognition Recognition The proof of excellence

2004: Dr. Majeed honored with the prestigious Ellis Island Medal of Honor from National Ethnic Coalition of Organizations, USA.

2010: Dr. Majeed received the Daniel B. Stateman award for distinguished alumni from Dr. David Taft at Long Island University’s 121st graduation ceremony in Brooklyn.

Dr. Majeed Receiving distinguished alumni Award of Trivandrum Medical College from Hon.Vayalar Ravi, Minister for Overseas Indian Affairs.

2009: Mr. Shaheen Majeed, (Marketing Director for Sabinsa) receiving Herbal Industry Leader Award from the American Herbal Products Association

2008 Sabinsa Corporation is the recipient of Frost & Sullivan’s 2008 North American Personal Care Ingredient Green Excellence of the Year Award. The award is in acknowledgment of Sabinsa’s strategically balanced green product offering, proactive and sustainable marketing practices, and the continuous ability to satisfy client needs in an increasingly diverse and green-conscious market space

2006 Sabinsa Corporation was awarded by Nutrition Business Journal (NBJ) * A product merit award for their branded L –(+) – Selenomethionine compound, Selenium SeLECT®

* An investment in science and Research award for Forslean® , the company’s branded and patented coleus forskohlii extract ingredient used to improve body composition.NBJ is a research, publishing and consulting company serving the nutrition, natural Products and alternative health care industries.

2003 Best Export Award - Overall GOLD 2002 Award for Highest Export of Value Added Spices by Spices Board, Govt. of India, Ministry of Commerce &

Industry. 2002 Award for Highest Export of Newly Developed Spice Products by Spices Board, Govt. of India, Ministry of

Commerce & Industry. 2002 Export Award in Recognition of Company’s Performance in “Chemicals Category” for the year 2001 – 02

by the Federation of Karnataka Chambers of Commerce & Industry (FKCCI) 2002 Award for Excellence in Export Achievement under 100% EOU Scheme in “Agro & Food” Sector in

Karnataka from Govt. of India, Ministry of Commerce & Industry for the year 2001-02 2001 Award for Achieving the Highest Export of Newly Developed Value Added Spice Products from India

during the year 1999-2000 by Spices Board, Govt. of India, Ministry of Commerce & Industry 2001 Award for Achieving the Highest Export of Value Added Spices from India during the year 1999-2000 by

Spices Board, Govt. of India, Ministry of Commerce & Industry 2001 Award for Outstanding Performance in the Export of Spices/Spice Products from India during the year

1999-2000 by Spices Board, Govt. of India, Ministry of Commerce & Industry 2001 Approval of In-house Research & Development Unit u/s 35(2AB) of Income-Tax Act 1961 from Govt. of

India, Ministry of Science & Technology, Department of Scientific and Industrial research. 2000 Certificate of Honour for Outstanding Performance in the Export of Spices/Spice Products for the year

1998 – 99 from India issued by Spices Board, Govt. of India, Ministry of Commerce & Industry 1997 Recognition of In-house Research & Development facility (Renewable from time to time) 1997 Recognised Export House from Govt. of India, Ministry of Commerce, DGFT, New Delhi.

1995–96 Certificate of Merit for Outstanding Export Performance in Spice Products, Vegetable Extracts, Organic Fine Chemicals, Essential Oils, Extracts & Oleoresins,Modified Starches & Enzymes, etc., from Govt. of India, Ministry of Commerce.

Page 10: Samidirect business-manual

Corporate Social Responsibility Corporate

Social Responsibility Corporate

Social Responsibility

Considering the importance of biodiversity of medicinal plants and to

maintain the sustainability for future generations, the company has taken

up a successful initiative over the last 10 years by undertaking and

promoting large scale commercial cultivation of medicinal plants globally.

SAMI initiated almost a decade ago, medicinal plant cultivation with a

handful of farmers. Over the years this effort has translated into a large

scale cultivation model involving more than 40000 acres and supporting

thousands of farmer families.

Sami supports its farmers with a buy back guarantee , crop insurance, bank

finance and ensures they receive a reasonable price for the produce

avoiding intermediaries.

Today, this successful model is being replicated in Africa and South East

Asia.

Page 11: Samidirect business-manual

Products Products Products

Sami Direct is a committed to offer you an unrivalled range of

Nutraceuticals followed by cosmeceuticals which has been acknowledged

by the world over for its highest quality and safety standards. Supported by

our own Sami labs R&D and Clinical Studies, Sami Direct is all set to usher in

a novel range of nutraceuticals and cosmeceuticals with a holistic

approach in leading the world to better health.

Sami has also developed the strength and infrastructure to offer services in

the areas of:

Healing in myriad ways

Customized Product Development

Formulation Development

Contract research

Clinical research

Non animal in-vitro efficacy and toxicity studies

Analytical Studies

Women 40+

®OsteoStrong

As women age, the body undergoes many changes and the major concern is

menopause, when hormone levels begin to drop and the menstrual cycle ceases.

Menopause is the permanent cessation of reproductive fertility some time

before the end of the natural life span. The decline in estrogen levels associated

with menopause puts women at increased risk for declining bone density and

fractures.

Osteoporosis literally means porous bone and is sometimes referred to as the

“silent disease” because bone loss occurs without symptoms. Although

osteoporosis can strike at any age, chances of it developing, increases with age.

Statistics show that one in two women of age 50 and older usually suffer an

osteoporosis-related fracture in their lifetime. Fortunately osteoporosis can be

prevented or treated.

OsteoStrong® by Sami Direct is a health supplement for 40+ women who face an

increased risk of declining bone density and fractures. Loaded with natural

ingredients like Calcium Citrate malate, Soy extract, Red Clover extract and

BioPerine®, OsteoStrong® not only strengthens your bones from within but also

helps prevent osteoporosis and postmenopausal symptoms in women.

Binds at estrogen receptors and

prevent the body from over-

producing estradiol

Mimics the action of estrogen &

along with most bio-available form

of calcium, helps in Bone Mineral

Density

Boosts progesterone expression and

help to normalize the body's

important estrogen to progesterone

ratio

KEY BENEFITS

Each Tablet contains:

Ingredient

Soy extract (40% Isoflavones)

Red Clover extract

Calcium Citrate malate

BioPerine®*

Quantity per Tablet

30 mg

10 mg

500 mg

5 mg

Suggested Use :One tablet twice daily

*Patented – US & International Patents

References:

1. Ajmandi, Bahram, H, Journal of the American College of Nutrition, Vol. 20, No. 5, 398S–402S(2001).

2. Van de Weijer, P., Isoflavones from red clover (Promensil®) significantly reduce menopausal hot flush symptoms compared with placebo. Maturitas, Volume 42, Issue 3, Page 187.

Page 12: Samidirect business-manual

Sami Direct’s Orgnanic Spirulina contains Spirulina, a natural source of vitamins, minerals, antioxidants and other nutrients, in combination with *Bioperine®, a patented bioavailability enhancer derived from black pepper fruit that enhances their uptake and utilization.

SpirulinaSpirulina is a marine algal source that supports optimal health and wellness, due to high concentration of essential nutrients. Spirulina is produced primarily from two species of cyanobacteria: Arthrospira platensis and Arthrospira maxima.

Spirulina is a microscopic, blue-green algal culture (a free floating filamentous cyanobacterium). Spirulina for dietary supplements is derived from Arthrospira platensis or Arthrospira maxima), Spirulina is a rich source of vegetable proteins, iron, pro-vitamin A carotenoids, vitamin B (thiamine), B (riboflavin), B 1 2 3

(niacin), B (pyridoxine), B (cobalamin), vitamin C, vitamin D, vitamin E, folate, 6 12

vitamin K, biotin, pantothenic acid, beta carotene (source of vitamin A), inositol, essential amino acids, and the rare essential fatty acid, GLA (gamma-linolenic acid).

Studies show that Spirulina preparations have significant antioxidant activity, benefit metabolism, detoxification, and immune functions; and support the management of inflammation and allergies.

Rich in antioxidant

Boosts energy and Cellular Health

P r o m o t e s M e t a b o l i s m ,

Detoxification & Immune Functions.

Supports the Management of

inflammation and allergies.

KEY BENEFITS

Suggested Use :One tablet twice or thrice daily

References:

1. Park, H.; Lee, Y.; Ryu, H.; Kim, M.; Chung, H.; Kim, W. (2008). "A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans". Annals of nutrition & metabolism 52 (4): 322–328.

2. Lu, H.K., Hsieh, C.C. Hsu, J.J., Yang, Y.K., & Chou, H.N. (2006). "Preventative effects of Spirulina platensis on skeletal muscle damage under exercise induced oxidative stress". European Journal of Applied Physiology 98 (2): 220–226

Alcoholism or alcohol dependency is a disease that manifests the following four

symptoms: craving, loss of control, physical dependence and addiction. Alcohol

hangover, an after-upshot of dehydration and intoxication, is a common

condition that causes substantial impairment to affected individuals. The

dehydration of the body is caused by alcohol, which is a diuretic. Hangover is

characterized by the constellation of unpleasant physical and mental symptoms

that occur after heavy alcohol drinking.

When alcohol is consumed, the liver breaks it down primarily into a toxic

substance called acetaldehyde. The build up of acetaldehyde in the liver results

in hangover symptoms such as headache, nausea, irritability and fatigue.

Accumulation of acetaldehyde at higher concentrations leads to the

development of physical symptoms of hangover, which include rapid pulse,

sweating, skin flushing, increased sensitivity to light and sound, redness of the

eyes, muscle aches and thirst. The dehydrating effect of alcohol is also

responsible for morning dizziness, tiredness and general body weakness.

Liver Support is a unique formulation from Sami Direct that offers a holistic

approach to the problems associated with alcohol dependency. It effectively

maintains balance, manages stress, helps to sober down and deal with the

effects of hangover.

Provides better ‘morning after’

effects

Helps to deal with the symptoms of

nausea, headache and dehydration

Effectively eliminates acetaldehyde,

the toxic by-product of alcohol

intake

Helps maintain healthy liver

functions

KEY BENEFITS

Each Capsule contains:

Ingredient

*

*

3Curcumin C Complex®

Fabenol®

Vit B12

Vit B6

Folic acid

Phyllanthus amarus

BioPerine®

Quantity per Capsule

250 mg

90 mg

5 mcg

1.5 mg

100 mcg

60 mg

5 mg

Suggested Use :One capsule twice daily

*Patented – US & International Patents

References:

1. Bharat B. Aggarwal Chapter 23 Curcumin Derived from Turmeric (Curcuma longa):a Spice for All Seasons. Phytopharmaceuticals in Cancer Chemoprevention. © 2005 by CRC Press LLC. p 349-387.

2. S.Priya and PR Sudhakaran. Curcumin-induced recovery from hepatic injury involves induction of apoptosis of activated hepatic stellate cells. Indian. J. Biochem. Biophys. Vol 45, 2008; pp. 317-325.

3. Chidi U. Igwe et al.,Assessment of the hepatic effects, phytochemical and proximate compositions of Phyllanthus amarus African Journal of Biotechnology Vol. 6 (6), pp. 728-731, 19 March 2007. pp 728 – 731.

Organic SpirulinaMaintaining Good Health For Healthy Liver

Liver Support

Each Tablet contains:

Ingredient

Spirulina

BioPerine®*

Quantity per Tablet

400 mg

2.5 mg

*Patented – US & International Patents

Page 13: Samidirect business-manual

A joint is formed by the ends of two or more bones that are connected by thick

bands of tissue called ligaments. For example, the knee joint is formed by the

lower leg bone, called the tibia or shinbone, and the thighbone, called the femur.

The hip joint is a ball-and-socket joint, formed by the ball, or femoral head, at the

upper end of the thighbone, and the rounded socket, or acetabulum, in the

pelvis.

Joint pain is a very common problem prevailing in almost every part of the world.

It is basically a symptom and not a disease and it has eventually become a part of

everybody’s life, especially aged people

Arthritis is a group of conditions involving damage to the joints of the body. The

most common form, osteoarthritis (degenerative joint disease) is a result of

trauma to the joint, infection of the joint or age.

Other arthritis forms are rheumatoid arthritis, psoriatic arthritis and

autoimmune diseases in which the body attacks itself. Septic arthritis is caused

by joint infection. Gout is another form of arthritis, caused by deposition of uric

acid crystals in the joint, causing inflammation.

3R Power™ is a sustained release composition containing herbal extracts and

nutrients that help support healthy joints and connective tissues in the body.

Helps to overcome joint pains

Effectively reduces inflammation of

joints (arthritis)

Prevents inflammation of the

tendons (tendonitis)

KEY BENEFITS

Suggested Use :One tablet twice daily

References:

1. Research Report – Sami Labs Limited.

Optimum 1 is a unique composition containing herbal extracts and nutrients

that help to support healthy blood sugar level.

Blood sugar refers to the amount of glucose present in the blood. Normally, in

mammals the blood glucose level is maintained at a reference range between

about 3.6 and 5.8 mM (mmol/L) or 64.8 and 104.4 mg/dL. It is tightly regulated as

a part of metabolic homeostasis, by the hormone insulin. Impaired insulin

secretion due to genetic or diet and lifestyle factors, or the inability to use insulin

i.e. insulin resistance encountered sometimes in obese individuals impact

glucose homeostasis.

Failure to maintain blood glucose in the normal range leads to conditions of

persistently high (hyperglycemia) or low (hypoglycemia) blood sugar. Diabetes

mellitus, characterized by persistent hyperglycemia is the most prominent

disease related to failure of blood sugar regulation. If left unchecked, can lead to

a number of serious health problems including blindness, kidney disease, stroke

and heart disease.

Optimum®1 is a carefully formulated product from Sami Direct that contains

effective ingredients that support normal blood sugar levels, when combined

with a healthy diet and lifestyle.

® Supports healthy blood sugar levels

Support the body’s natural ability to

utilize insulin

Effectively manages Impaired

Glucose Tolerance

KEY BENEFITS

Each Tablet contains:

Ingredient

Momordicin®

Chromium Picolinate

Silbinol®

BioPerine®

*

Quantity per Tablet

100 mg

50 mcg

100 mg

2.5 mg

Suggested Use :One tablet twice daily

*Patented – US & International Patents

References:

1. DiSilvestro, R, et al. Acute Absorption of Various Types of Chromium Supplement Complexes. Accepted for presentation at the Federation of American Societies for Experimental Biology (FASEB) annual meeting, San Diego, CA, April 4, 2005..

2. Anderson, RA, et al. Lack of Toxicity of Chromium Chloride and chromium Picolinate in Rats. J Amer Coll Nut Vol. 16, No. 3 1997; 273-279.

3. Saifi, A.Q., Shinde, S., Kavishwar, W.K., and Gupta, S.R. (1971) Some aspects of phytochemistry and hypoglycaemic actions of Pterocarpus marsupium (Papilionaeceae). J. Res. Ind. Med., 6(2), 205-207.

Keep all supplements out of reach of children.

ADVANCED JOINT SUPPORT FORMULARelief Rebuild Restore • •

3 ™R PowerBlood Sugar Balance

®Optimum 1

Each Tablet contains:

Ingredient

Glucosamine HCl

Boswellin® PS

Curcumin C3 Complex®

BioPerine®

**

*

*

Quantity per Tablet

750mg

100mg

100mg

5mg

* **

Patented – US & International PatentsPatent Pending

Page 14: Samidirect business-manual

It is a mistaken belief that in order to lose weight, one must eliminate fat from the diet. On the contrary, eliminating fats from the diet totally can be very harmful to the body as good fats are essential to the body and play critical roles in metabolism and wellness.

Essential fatty acids (EFAs) are beneficial fats chemically classified under polyunsaturated fatty acids (PUFA) that cannot be formed by the body and need to be supplied by the diet. The two primary EFAs are known as alpha-linolenic acid (Omega-3) and linoleic acid (Omega-6). Omega-9 fatty acids (oleic acid) are non-essential fatty acids, as they can be produced from the EFAs. However, deficiency does occur when the diet is deficient in EFAs.

Essential fatty acids are required for energy production in the body, cardiac function, health of hair, skin and nails, hormone production, brain function, and for the integrity of the very structure of cells. Symptoms of omega-3 fatty acid deficiency include extreme tiredness (fatigue), poor memory, dry skin, heart problems, mood swings or depression, and poor circulation.

Omega BioPlus™ contains a vegetable derived omega 3, omega 6 and omega 9 fatty acids composition in a specific scientifically validated proportion to support healthy cell membranes and cellular functions, and attractive skin, hair and nails. The fatty acids composition is combined with sesame oil antioxidants and a bioavailability enhancer derived from black pepper fruit.

It supports the liver and kidney

functions; and helps in maintaining

normal b lood pressure and

cholesterol levels.

It supports a healthy immune

system, and cardiovascular health

and wellness.

I t b e n e f i t s i n s u p p o r t i n g

cardiovascular health, joint health;

neuronal health and healthy skin,

hair and nails.

KEY BENEFITS

Suggested Use :One softgel twice daily

References:

1. Szapary, O. Philippe. The Heart Health Benefits of Omega-3 Fatty acids. Advanced Studies in Medicine. Vol 5 (6A); p-511-517.

2. Harbige L.S.; Layward L.; Morris-Downes M.M.; Dumonde D.C.; Amor S. The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-β1) up-regulation and increased prostaglandin E2 (PGE2) production. Clinical & Experimental Immunology, Volume 122, Number 3, December 2000, pp. 445-452(8).

3. Hirose, N et al. Inhibition of cholesterol absorption and synthesis in rats by sesamin. Journal of Lipid Research Volume 32, 1991. P 629-638.

The word “Detox” means detoxifying the body from toxins and other harmful chemicals and cleansing it for proper functioning and optimal health.

Body cleansing or detoxification helps rid the body of accumulated harmful substances, such as heavy metals and environmental toxins that exert a negative effect on the health of an individual.

There are two major approaches to the detoxification programme.1. Antioxidant Support. Oxidation occurs at the cellular level, so detox must occur there as well. Any deficiency of antioxidants in the diet causes problems associated with removal of toxins .

2. Supporting healthy liver functions. A good detoxifying agent removes impurities from the blood through the liver. Liver is an important organ where toxins are processed so that they can be removed from the system. It is also responsible for detoxifying the body of poisonous substances by transforming and removing toxins and wastes.

SAMI DIRECT’s For Detoxification is a judicious blend of ingredients that can be used to provide these benefits. The ingredients have been chosen with care and formulated scientifically to offer a comprehensive and holistic support to the detoxification process.

Supports the body’s natural

mechanisms to eliminate toxins

Supports digestion

Supports the maintenance of

normal liver functions

S u p p o r t s n o r m a l m eta b o l i c

processes leading to sustained

energy levels and stamina

KEY BENEFITS

Each Capsule contains:

Ingredient Quantity per Capsule

5 mg

100 mg

100 mg

50 mg

50 mg

Suggested Use :One capsule daily upto 30 days. To be repeated after every 6 months.

References:

1. Picrorhiza kurroa Monograph – Alternative Medicine Review, Volume 6, No.3, 2001, 319 – 321.

Omega BioPlus™

EFFECTIVELY REMOVES TOXINS

For Detoxification

Each Softgel contains:

Ingredient

Omega 3 Fatty Acids

Sesamin Complex

BioPerine®*

Quantity per Softgel

500 mg

10 mg

5 mg

*Patented – US & International Patents

Peppermint oil

FenuFibers®

Licorice extract

Neem Leaf Extract

Picroliv® - Apocynin 5% (Picrorhiza kurroa)

LactoSpore® (15 mio)

10 mg

Page 15: Samidirect business-manual

3Curcumin C Power™ offers the health benefits of quality curcuminoids from turmeric roots, in a convenient form that is better absorbed in the body. Curcuminoids are valued for their antioxidant and anti-inflammatory roles in biological systems.

Most degenerative diseases are driven by underlying chronic sub-clinical inflammation. The old view of the inflammation is that it represents the healing process. This is true to a certain extent; however when the inflammation becomes chronic, it becomes a disease.

NF-kB (Nuclear Factor-KappaB) is a cell-signaling molecule for inflammation; its activation induces the expression of cyclooxygenase – (COX-2), an enzyme that triggers tissue inflammation. NF-kB resides in the cytoplasm of the cell and is bound to its inhibitor. Injuries and inflammatory stimuli, such as free radicals, release NF-kB from its inhibitor.

NF-kB activation is a major mediator of inflammation in most diseases and inhibition of NF-kB can help prevent/delay the onset of the disease. Curcuminoids, natural compounds derived from turmeric roots, inhibit NF-kB.

3Curcumin C Power™ is a proprietary composition of Curcuminoids containing 3Sabinsa’s patented Bioprotectant Complex – Curcumin C Complex®* and the

natural patented bioavailability enhancer, BioPerine®*, derived from black pepper fruit, which enhances the absorption of curcuminoids.

F a s t - a c t i n g , l o n g - l a s t i n g ,

bioavailable Curcumin

Supports overall wellness and good

health

KEY BENEFITS

Suggested Use :One tablet twice daily

Obesity is recognized as a chronic disease almost in all countries. High

prevalence of obesity is of great public health concern because excess body fat

leads to a higher risk for premature death, type 2 diabetes, hypertension,

dyslipidemia, cardiovascular disease, stroke, gall bladder disease, respiratory

dysfunction, gout, osteoarthritis, and certain kinds of cancers.

Overweight and obesity are the results of several factors. For each individual,

body weight is determined by a combination of genetic, metabolic, behavioral,

environmental, cultural and socioeconomic influences. For the vast majority of

individuals, however, overweight and obesity are the results of excess calorie

consumption and/or inadequate physical activity. Weight management means

keeping body weight at a healthy level. LeanGard® contains an advanced

spectrum of natural ingredients that work synergistically to support satiety, lean

body mass, and a healthy body composition, with a beneficial impact on healthy

body weight.

LeanGard® is a proprietary blend of natural extracts that support healthy body

composition and weight management. It is a botanical weight management

formula composed of Coleus forskohlii extract, Garcinia cambogia extract with

Garcinol and Piper nigrum extract. The composition of LeanGard® is aimed at

overcoming the shortcomings of the individual botanical ingredients, facilitating 1their actions and improved bioavailability to the target tissues and cells.

Helps to increase the lean body

mass

Decreases body fat accumulation

Stimulates the release of fatty acids

from the body fat for energy uptake

Provides antioxidant benefits

Supports satiety

Supports general fitness and overall

well-being

KEY BENEFITS

Each Capsule contains:

Ingredient

LeanGard® Blend

Quantity per Capsule

500 mg

Suggested use level: One Capsule twice daily

References:

1. A Prospective, Controlled, Randomized, Double Blind, Parallel-Group Study Comparing “The Efficacy and Safety of Oral Administration of LeanGard® Capsule with respect to Placebo for Twelve Weeks in Weight Management”. Sabinsa Study Report Protocol Number: CPL/09/LGD/MAR/07.

2. Conte A.A. A Non-Prescription Alternative in Weight Reduction Therapy. The Bariatrician. 1993: 17-19.

3. Conte A.A. The effects of (-) - Hydroxycitrate And Chromium (GTF) On Obesity. J Amer Coll Nutr.1994 (October);13 (5): 535 .

4. Katts GR, Pullin D, Parker LK, Keith PL, Keith S. Reduction Of Body Fat As A Function Of Taking A Dietary Supplement Containing Garcinia Cambogia Extract, Chromium Picolinate And L-Carnitine - A Double Blind Placebo Controlled Study. Abstract/Poster presented at a symposium on obesity organized by the Mexican Sociedad Medical del Sureste para el Estudio de la Obesidad, March 4, 1995, Merida, Yucatan, Mexico.

5. Badmaev V, Majeed M. Open Field, Physician Controlled, Clinical Evaluation Of Botanical Weight Loss Formula Citrin®. Nutracon 1995: Nutraceuticals, Dietary Supplements And Functional Foods. Day One (Sponsored by Global Business Research Ltd.). Published in the symposium proceedings.

6. Thom E. (-)Hydroxycitrate (HCA) In The Treatment Of Obesity. Int J Obesity. 20 (4): 75.

Each Tablet contains:

Ingredient

*

*

3Curcumin C Complex®

BioPerine®

Quantity per Tablet

525 mg

5mg

*Patented – US & International Patents

Weight Management

LeanGard®

Natural Bioprotectant

3Curcumin C Power™

Page 16: Samidirect business-manual

Free radicals are highly reactive byproducts of biological processes in the body. Antioxidants neutralize free radicals in the body, and protect cells against the ravages of environmental and ingested toxins, that accelerate the aging process, and trigger inflammation, which is the root cause of chronic diseases.

A good quality natural antioxidant derived from dietary sources or in the form of supplements, provides anti-aging protection against degenerative diseases and helps to slow down the aging process of the skin, cells, tissues and organs. Our bodies produce their own antioxidants, but as we get older, the ability to produce antioxidants weakens.

The multifaceted benefits of antioxidant supplementation will be considerably useful, for people dealing with stress, dieters limiting their calories to 1,200 per day or less, people on a low-fat diet, smokers, older adults, and people with a family history of heart disease or cancer.

AntiOxidant is a proprietary blend of natural ingredients from Sami Direct that captures the combined benefits of powerful antioxidant molecules.

Inflammation is a natural response to injury, and triggers healing. However, uncontrolled inflammation is believed to be the underlying cause of chronic conditions including cardiovascular disease, various forms of cancer, metabolic syndrome, and obesity.

Supports a healthy immune system

and a balanced inflammatory

response

Not only scavenges free radicals, but

also prevents their formation

KEY BENEFITS

References:

1. Osawa,T. et al. (1995) Antioxidative activity of the tetrahydrocurcuminoids. Biosci. Biotechnol. Biochem. 59(9): 1609-12.

Dr. Peter Mitchell was awarded the 1978 Nobel Prize for Chemistry for his

discovery of the Chemiosmotic mechanism of ATP Synthesis which includes the

vital role of Coenzyme Q in the body’s energy systems.10

Coenzyme Q10

Coenzyme Q , abbreviated at times to CoQ is a 1, 4 - benzoquinone, where Q 10 10

refers to the quinone chemical group, and 10 refers to the number of isoprenyl

chemical subunits.

Coenzyme Q (CoQ ) is a compound found naturally in the energy-producing 10 10

center of the cell known as the mitochondria in most eukaryotic cells. CoQ is a 10

component of the electron transport chain and participates in aerobic cellular

respiration. It is involved in generating energy in the form of ATP (Adenosine

triphosphate). 95% of the human body’s energy is generated this way. Therefore,

those organs with the highest energy requirements—such as the heart, liver and

kidney – have the highest CoQ concentrations. It is logical to conclude that a 10

deficiency in coenzyme Q in any of the body's cells would affect cellular 10

functions, metabolic processes and energy generation.

Coenzyme Q supports cardiovascular functions, boosts energy metabolism, a 10

healthy immune system and the body’s natural healing processes.

Supports vitality and energy Level.

Supports a healthy immune system

and resistance to stress and

infections.

Supports improved exerc ise

tolerance and athletic performance.

Effects “beauty from within”

supporting healthy skin, hair and

nails.

Supports healthy ageing and

longevity.

Helps in prevention of loss of muscle

tone, when given as an adjunct

therapy alongwith cholesterol

lowering products.

CoQ Energizer™ is responsible for

95% of body’s Energy Production.

With ageing and other medication,

the CoQ Energizer™ level comes

down hence CoQ Energizer has to be

supplemented externally.

Assists in improving cardiac Health

& Heart related diseases.

Assists in treating male infertility

cases.

KEY BENEFITS

Each Softgel contains:

Ingredient

Coenzyme Q10

Vitamin E

BioPerine®*

Quantity per Softgel

60 mg

50 mg

2.5 mg

Suggested use level: One Softgel twice daily.

*Patented – US & International Patents

Each Softgel contains:

Ingredient

*

*

*

3Curcumin C Complex®

Tetrahydrocurcuminoids

Alpha tocopherol acetate

Selenium SeLECT® Pure

BioPerine®

Quantity per Softgel

50 mg

10 mg

25 mg

50 mcg

1 mg

Suggested Use :One softgel twice daily

*Patented – US & International Patents

Cellular Bio-energizer

CoQ Energizer™

Powerful Antioxidant

AntiOxidant