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Slide 2 Safe Composition of Complex Medical System University of Illinois at Urbana-Champaign Computer Science Department Fall 2010 Slide 3 Medical Accidents More than 100,000 safety-related medical incidents a year in US According to Health Grades Caused by human error Drug-based adverse events Overlooked device interlocks Alarm fatigue Preventable by automated supervision Slide 4 The MDPnP Program MDPnP : The Medical Device Plug-and-Play MDPnP Chair: Dr. Julian Goldman Inter-disciplinary, multi-institutional medical device informatics research program. Leading patient-centric Integrated Clinical Environment (ICE) standard MDPnP group is based at CIMIT and Massachusetts General Hospital.CIMITMassachusetts General Hospital Slide 5 System Overview Device Virtual Device Virtual Device False Alarm Detector.. Device Virtual Device ICE Supervisor.. Pre-condition Checker Safety Interlock Manager Patient Clinician Slide 6 UIUC Demos We demonstrate three related safe MDPnP technologies: NASS Framework- Airway Laser Surgery Ensuring distributed medical devices to enter failure safe states when the supervisor loop fails Context Aware Alarm Processing Using correlations between vital signs under a given medical procedure to validate alarms or reconstruct missing measurement Patient Screening for Safe MDPnP Identify potential safety hazards Slide 7 UIUC Demos The presentations are based on the live demo at MDPnP lab at CIMIT. We would like to thank all the participants from Mass General, FDA, UPenn and U of Kansas, for their comments. Slide 8 Publications Y. Li, Y. Sun, P. Sondhi, L. Sha, and C. Zhai, Reconstructing missing signals in multi-parameter physiologic data by mining the aligned contextual information, in Proceedings of Computing in Cardiology Conference 2010, Belfast, Northern Ireland, United Kingdom, Sep. 26-29, 2010. P. Sondhi, J. Sun, C. Zhai, R. Sorrentino, M. S. Kohn, S. Ebadollahi, and Y. Li, Medical case-based retrieval by leveraging medical ontology and physician feedback, UIUC-IBM at ImageCLEF 2010. CLEF Y. Li, J. H, C. Zhai, and Y. Chen, Improving one-class collaborative filtering by incorporating rich user information, in CIKM 2010: Proceedings of the 19th ACM international conference on Information and knowledge management, Toronto, Canada, 2010. ACM. (acceptance ratio: 13.4%) Slide 9 Publications P. Sondhi, M. Gupta, C. Zhai and J. Hockenmaier, Shallow information extraction from medical forum data, in Proceedings of COLING 2010,pp. 1158- 1166 C. Kim, M. Sun, S. Mohan, H. Yun, L. Sha, and T. F. Abdelzaher, A framework for the safe interoperability of medical devices in the presence of network failures, in Proceedings of the 1 st ACM/IEEE International Conference of Cyber-Physical Systems, 2010, pp. 149-158 M. Rahmaniheris, C. Kim, S. Bak, and L. Sha, A multi-layer dependency framework for analysis of safety-critical embedded systems, submitted to DSN 2011