Samantha MartinezPeriod 3

Ritalin

• Ritalin is the trademarked name for methylphenidate.

• IUPAC name: methyl phenyl(piperidin-2-yl)acetate• Chemical Formula: C14H19NO2

• Street Names: Kibbles and Bits, Kiddy Cocaine, Diet Coke, Skittles, R Pop, Coke Junior, Smarties, Rids

Classification

• Ritalin is belongs to the group of medicines known as central stimulants.

• Under the Controlled Substances Act, Ritalin is a Schedule II drug.

History• 1944- Ritalin was first synthesized by chemist Leandro Panizzon.• 1950s- The therapeutic value of Ritalin began to be researched.• 1954- Ritalin became a known stimulant.• 1957- Ciba Pharmaceutical Company began marketing Ritalin to treat

chronic fatigue, depression, and narcolepsy.• 1960s- Ritalin was used to counteract the symptoms of barbiturate

overdose. Also, Ritalin was mixed with other products and was marketed as Ritonic to improve mood. Ritalin was also started to be used to treat kids with ADHD.

• 1970s-1980s- The use of Ritalin increased rapidly.• 1991-1999- Ritalin sales in the United States increased by 500%.• 2000- Janssen Pharmaceutical got the approval to market Concerta.

Production

• Ritalin is synthesized in the United States, Mexico, Spain, and Pakistan.

• There is no information available on the production of Ritalin.

The User

• The common abusers of Ritalin are teens and 20-somethings.

• Ritalin is abused by these people to lose weight, study for exams, or to just get high.

• Ritalin is typically obtained by these people by faking symptoms to get a prescription or bought off of friends.

Effects

• Ritalin is administered orally in the forms of tablets, capsules, or liquid. It can also be snorted or given in the form of a patch. It is a very popular medicine for children with ADHD.

• Ritalin increases the production of dopamine and blocks transporters allowing more dopamine to reach receptors, increasing attention signaling.

• Ritalin is highly addictive and tolerance is developed over time leading to the user taking higher and higher doses.

Risks

Negative Side Effects of Ritalin• Appetite suppression• Wakefulness• Euphoria• Irregular or rapid heart rate • Skin rash• Nausea and vomiting• Agitation• Seizures, followed by coma• Anxiety• Formication

• Ritalin has an LD50 of 190 mg/kg in mice.

Detection

• Since Ritalin has a half life of 3 hours, it leaves the body within a few days.

• Ritalin cannot be detected on a standard 5 panel drug test, but can show up positive for a drug screen panel for amphetamines.

• Ritalin is present in urine for 1-2 days after dosing.

• Ritalin is present in hair for at least 90 days.

Consequences

• Group or individual therapy is available to someone who is addicted to Ritalin once the detox process begins.

• The legal consequences for Ritalin include:– First trafficking offense: 5-20 years in prison and a fine of

up to $1,000,000– Illegal distribution of Ritalin is done in a group of two or

more: 5-20 years in prison and a fine of up to $5,000,000– If the distribution of Ritalin results in death or serious

injury: 20 years-life in prison

Works Cited• Blog, A. (2012, March 27). How long does Ritalin stay in your system?. Retrieved from

http://prescription-drug.addictionblog.org/how-long-does-ritalin-stay-in-your-system/• Myers, R.L. (2007, August 30). The 100 Most Important Chemical Compounds: A Reference Guide (Google

eBook). Retrieved from http://books.google.com/books?id=a4DuGVwyN6cC&pg=PA178&lpg=PA178&dq=named+ritalin+after+his+wife&hl=en#v=onepage&q=named%20ritalin%20after%20his%20wife&f=false

• Seth. (2002, December). Summary of the Medical Uses of Methylphenidate. Retrieved from http://www.erowid.org/pharms/methylphenidate/methylphenidate_info1.shtml

• Sherzada, A. (2012, February 5). An Analysis of ADHD Drugs: Ritalin and Adderall. Retrieved from http://scholarspace.jccc.edu/cgi/viewcontent.cgi?article=1021&context=honors_journal

• (2013). Newly Approved Drug Therapies (637) Concerta, Alza. Retieved from http://www.centerwatch.com/drug-information/fda-approvals/drug-details.aspx?DrugID=637

• Production of Ritalin. Retieved from http://web1.caryacademy.org/facultywebs/gray_rushin/StudentProjects/CompoundWebSites/2000/Ritalin/production.html

• (2005, May 5). Ritalin. Retrieved from http://www.cesar.umd.edu/cesar/drugs/ritalin.asp#history• Ritalin. Retrieved from http://www.drugfree.org/drug-guide/ritalin• (2013). Ritalin Addiction Treatment Help. Retrieved from

http://www.ritalinabusehelp.com/ritalin-addiction-treatment-help• (2013). Ritalin Classification. Retrieved from http://www.healthcentral.com/adhd/h/ritalin-classification.html• (2013). Ritalin Street Names. Retrieved from http://www.ritalinabusehelp.com/ritalin-street-names• (2001, February 25). Teens Abusing And Selling Ritalin for High. Retrieved from

http://abcnews.go.com/GMA/story?id=125327#.UOp9u2-5OSo