RICHARD MK ADANU UNIVERSITY OF GHANA MEDICAL SCHOOL MEDICAL RESEARCH.
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Transcript of RICHARD MK ADANU UNIVERSITY OF GHANA MEDICAL SCHOOL MEDICAL RESEARCH.
RICHARD MK ADANUUNIVERSITY OF GHANA MEDICAL SCHOOL
MEDICAL RESEARCH
What is research?
The search for knowledge or any systematic investigation to establish facts
Basic research
Research that is carried out to increase understanding of fundamental principles.
Usually has no direct or immediate commercial benefits
Serves as the basis for many commercial products
Generates new ideas, principles and theories
Applied research
Research that is aimed at discovering, interpreting and the development of methods and systems for the advancement of knowledge on a wide variety of scientific matters
Other terminology
Observational researchInterventional research
Reasons for doing research
To obtain answers to questionsTo solve a problemTo improve the health of peopleTo improve practiceTo advance one’s career
Enjoying and advancing in research
Gaining research skillsLearning from established researchersBeing part of a research teamCollaborating with other researchers
Conducting research
In a university (medical school) settingIn regular clinical practice
Regulating research
Need for ethical committeesNeed to submit research proposals for reviewNeed to protect the rights of research
subjectsNeed for informed consent of participants
Belmont Report: 1974
Three Ethical Principles should guide medical research
1. Respect for Persons2. Beneficence3. Justice
Belmont Report
1. Respect for Persons individuals be treated as autonomous human beings
and be allowed to choose for themselves extra protection for individuals with impaired ability
to decide for themselves
Belmont Report
2. Beneficence Do no harm (non-maleficence) Minimization of harms Maximization of benefits
Belmont Report
3. Justice research is designed so that its burdens and benefits
are shared equitably among groups of populations fairness in the selection of research subjects, e.g.,
one should not select subjects based on their easy availability or their compromised position (e.g., individuals in a mental institutions)
Steps in conducting research
Identify a research topicFormulate research questionsDo a literature reviewRevise your research questionsFormulate a hypothesisDesign a data collection instrumentSubmit proposal for ethical approvalSubmit proposal for fundingCollect dataEnter and analyze dataReport research findings
WRITING GRANT PROPOSALS
Building skills
Writing scientific papers with referencesFollowing instructionsBeing at home with the internetChecking e-mailsWriting and getting feedbackWriting and justifying budgetsMaking oral presentations
Process
Identify call for proposalsRead instructions carefullyDo background researchWrite proposalObtain peer reviewSubmit
Call for proposals
Google searchInformation from friends and international
contactsInformation from journalsNIH calls for proposals
Preparations
Develop research or intervention ideas into proposals which you keep
Talk with other people
Following instructions
Cover letterPage limitWord countFont sizeProposal sections and orderSubmission deadlineReference format
Background research
Literature review What is known about topic What is not known about topic
Find knowledge gaps that your work can fill How will your work add to knowledge
Give enough time for work on submission
Components of proposal
Executive summaryStatement of needProject DescriptionBudgetConclusion
Executive Summary
Summarize key informationShould include
Problem Solution Funding Requirements Characteristics of your organization
Statement of need
Support your statements with factsGet straight to the pointBe persuasive
Project description
Describes project implementation and evaluation
Should include Objectives Methodology Analysis Staffing Evaluation Dissemination Sustainability
Budget
Must be an obvious product of project designCan be divided into personnel and non-
personnel costs Personnel
Salaries, benefits, consultants Non-personnel
Travel, equipment, printing
Budget justification
Reason why so much money is neededStraight to the pointObjective arguments
Conclusion
Summarizes main pointsBriefState what you want to do and whyEmphasize need for funding
Peer review
Consult experts while writing proposalListen to comments and make changesWrite and re-writeNo typos or grammatical errors
Basic elements of a proposal
What is the problem?What do you intend to do about it?How will you measure your success?
Writing a research document
Sections of a dissertation or thesis
AbstractIntroductionLiterature ReviewMethodologyResultsLimitationsDiscussionConclusion and recommendationsReferences
Modification for a journal article
AbstractIntroductionMethodologyResultsDiscussionConclusion and recommendationsReferences
Abstract
Usually a 150 word limitStructured abstract
Objectives Setting Methods Results Conclusion
Descriptive abstract Summary of paper without headings
Introduction for a thesis
Background information Reasons for selecting topic Information about study area
Problem statement A detailed and expanded description of the
subject being studied What are the problems arising because this
research has not been doneJustification
Reasons why this subject is worth studyingObjectives
What do you hope to learn from the study
Parts of the introduction for a journal article
What is known about the topic Current knowledge about research topic Brief account of most important work in the field
What is unknown about the topic Questions raised by important current research
What does this work seek to add to current knowledge Questions being addressed by this work
Content of introduction for a journal article
The known, the unknown, the research question
Existing key researchStatement of type of study designObjective of studyUse only a few references
Literature review
What is known about the subject?What questions have been raised by previous
research?What will this study add to the existing pool
of knowledge?
Methodology
Subject selectionData collectionData collection toolsData handlingData analysis
Results
What was found? Best divided into sections
Limitations
What are the shortcomings of the study?
Discussion
Summary of main resultsExplanation of resultsComparison of results with previous work
For each result item there should be a discussion
Conclusions and Recommendations
What have you learnt?What needs to be done?
References
Vancouver styleHarvard style
Getting published
Select appropriate journalRead instructions for authorsRead papers from journalGet your manuscript to match journal
requirementsSubmit paperAct on reviewer commentsHave no fear of reject letters
Finally…..
A research career is a worthwhile and enjoyable one to pursue
Research should not be far removed from practice
Anyone with research and writing skills can get published