Revised Pharma II May 2010psychCDONCOLOGY

8/8/2019 Revised Pharma II May 2010psychCDONCOLOGY

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CENTRO ESCOLAR UNIVERSITY

COLLEGE OF NURSING

Manila*Makati*Malolos

Syllabus

PHARMA1 PHARMACOLOGY II Unit: 3 LEC

Subject Title Subject DescriptiveTitle Hours: 54 LEC

PLACEMENT : 3rd Year, 2nd Semester

COURSE DESCRIPTION : The course deals with the study of pharmacology as an integral part of nursing care. This will include pharmacodynamics,

pharmacokinetics, clinical/therapeutic uses and toxicology of drugs.

PRE-REQUISITE : NCM 102, PHARMACOLOGY I

TERMINAL COMPETENCY: Given a client in the clinical setting, the student will be able to apply the concepts and principles of pharmacology to ensure safe

and quality care to patients through correct administration of drugs, effective assessment of drug effects and provision ofrelevant health teaching about drugs and drug regimen .

INTERMEDIATE

COMPETENCIES

CONTENT SUGGESTED TEACHING

STRATEGY/

METHODOLOGY

TIME

ALLOTMENT

At the end of the unit, thestudents will be able to:

1.Discuss the definition ofpsychopharmacology and its

significance to nursing practice.2.Discuss briefly basic concepts

of psychiatric drugs

PRELIM

UNIT I. PSYCHOPHARMACOLOGY

Foundations of Psychopharmacology1. Definition

1.1 antipsychotics,1.2 antidepressants,

1.3 mood stabilizers,

Lecture-Discussion

Case Study

Workshops

1 hour

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1.4 anxiolytics, and

1.5 stimulants

Actual Visits to Clinical Areas

Interviewing nurses in the workplace

UNIT II ANTIPSYCHOTIC DRUGS1. CONVENTIONAL ANTIPSYCHOTICS

2. ATYPICAL ANTIPSYCHOTICS3. NEW GENERATION ANTIPSYCHOTIC

4. DRUGS USED TO TREAT EXTRAPYRAMIDAL SIDE

EFFECTSUNIT III ANTIDEPRESSANTS

1. Tricyclic and the related cyclic antidepressants

2. Selective serotonin reuptake inhibitors (SSRIs)3. Monoamine oxidase inhibitors (MAOIs)

4. Other antidepressants:4.1 Venlafaxine (Effexor),

4.2 Bupropion (Wellbutrin),4.3 Trazodone (Desyrel), and

4.4 Nefazodone (Serzone)

UNIT IV Mood Stabilizers1. Lithium is the most established mood stabilizer;

2. Carbamazepine (Tegretol)

6 hour

3 hours

3 hours

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3. Valproic acid (Depakote, Depakene),

4. Others:4.1.1Gabapentin (Neurontin)

4.1.2Lamotrigine (Lamictal)4.1.3Clonazepam (Klonopin).

UNIT V ANXIOLYTICS1.BENZODIAZEPINES

2. NONBENZODIAZEPINESUNIT VI Stimulants

1. Methylphenidate (Ritalin),2. Pemoline (Cylert), and

3. DextroamphetamineUNIT VII. SPECIAL DRUGS

1. Disulfiram (Antabuse)2. Cognitive enhancers

a. Stimulant Cognitive enhancersi. Donezepil (Aricept)

ii. Galantamine ( Reminyl)iii. Rivastigmine (Exelon)

b. Non-stimulant cognitive enhancersi. Atomoxetine(Strattera)

3 hours

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INTERMEDIATE

COMPETENCIES

CONTENT SUGGESTED TEACHING

STRATEGY/

METHODOLOGY

TIME

ALLOTMENT

EVALUAT

MEASUR

REQUIREM

At the end of the unit, the

students will be able to:At the end of this unit the student

will be able to:A. Provide safe and quality care

1. Explain the mechanism s ofaction of drugs used for

neurological disorders2. Identify the mechanism of

actions, uses, and side effects ofdrugs used for neurologic

disorder3. Describe the three general

adverse effects associated withdrugs for neurologic disorders

4. Describe the nursing processincluding client teaching related

to drugs for neurologic disorders

MIDTERMS

Drugs for Disturbances in Neurologic Function, Eyeand Vision Disorders, Hearing Disorders and

Muskuloskeletal Disorders

UNIT V. Drugs for Neurologic Disorders1. Drugs for Seizure Disorders

12.1. Definition/Classification of Seizures1.2. benzodiazipines

1.3. hydantoins1.4. succinimides

1.5. Miscellaneous Anticonvulsants1.5.1. carbamazepine

1.5.2. gabapentin1.5.3. lamotrigine

1.5.4. levetiracepam1.5.5. oxcarbazepine

1.5.6. primidone1.5.7. tiagabine

1.5.8. topiramate1.5.9. valproic acid1.5.10. zonisamide

1.6. Drug of choice for each type of seizure

2. Parkinsons Disease2.1. Dopamine Agonists

2.1.1. amantadine2.1.2. apomorphine

2.1.3. bromocriptine mesylate2.1.4. carbidopa

2.1.5. levidopa

2.1.6. pergolode mesylate2.1.7. pramipexole2.1.8. ropinirole

2.2. COMT Inhbitor2.2.1. entacapone

2.3. Anticholinergic Agents2.4. Miscellaneous Antiparkinsonian Agents

2.4.1. selegiline

Claytons Basic Pharmacology forNurses 14th edition pp. 296-315

Claytons Basic Pharmacology forNurses 14th edition pp. 231-248

2 hour Paper and Penc

Recitation

Individual/Grou

Requirement:

1.Case Study on

following:- Effective Prac

AdministeringMedications

-Common ReasMedication Err

Among Nurses

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INTERMEDIATE COMPETENCIES CONTENT

At the end of the unit, the students will be able to:1.Discuss the different drugs appropriate for the treatment of

different disorders.2.Discuss briefly basic concepts of drugs like sources, drug

names, standards, information and evaluation.

FINALS

UNIT I. Drugs for Communicable Diseases

5. Pulmonary Tuberculosis5.1 Definition

5.2 Primary Drugs5.2.1 Streptomycin

5.2.2 Isoniazid

5.2.3 Rifampicin5.2.4 Pyrazinamide

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5.2.5 Ethambutol

5.3 Secondary Drugs5.3.1 Capreomycin

5.3.2 Ethionamide5.3.3 Para-aminosalicylate sodium

5.3.4 Cycloserine1.4 Phases of Treatment

1.4.1 Initial Phase1.4.2 Continuation phase

2. Pneumonia2.1 Definition

2.2 Drugs2.2.1 Streptococcal pneumonia

a. Penicillinb. Cefotaxime

c. Fluoroquinolone2.2.2 Haemophilus pneumonia

a. Amoxicillin-Clavulanateb. Non-beta-lactamase- Amoxicillin

2.2.3 Mycoplsma pneumoniaa. Macrolide

b. Tetracycline2.2.4 Viral Pneumonia

a. Oseltamivirb. Zanamivir

2.2.4 Chlamydia pneumoniaa. Fluoroquinolone

2.2.5Hospital-acquired Pneumonia/Pseudomonas Pneumoniaa. Penicillin + Ciprofloxacin

b. Levofloxacinc. Aminoglycoside

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2.2.6 Klebsiella pneumonia

a. Meropenemb. Levofloxacin

c. Piperacillin/Tazobactam + Amikacin3. Malaria

3.1 Definition3.2 Drugs

3.2.1 Chloroquine3.2.2 Primaquine

4. Leptospirosis4.1 Definition

4.2 Drugs4.2.1 Mild Leptospirosis

a. Doxycyclineb. Amoxicillin

4.2.2 Moderate to Severe Leptospirosisa. Penicillin G

b. Ampicillinc. Ceftriaxone

5. Filariasis5.1 Definition

5.2 Drugs5.2.1 Diethylcarbamazine

5.2.2 Albendazole5.2.3 Doxycycline

6. Typhoid fever6.1 Definition

6.2 Drugs6.2.1 Ciprofloxacin

6.2.2 Chloramphenicol6.2.3 Azithromycin

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7. Viral Hepatitis


7.2.1 Lamivudine7.2.2 Interferon

8. Rabies8.1 Definition

8.2 Drugs8.2.1 Rabies Immunoglobulin (RIG)- post-exposure prophylaxis

9. Tetanus9.1 Definition

9.2 Drugs9.2.1 Penicillin

9.2.2 Metronidazole10. Gonorrhea


10.2.1 First Linea. Ceftriaxone

b. Doxycycline10.2.2 Alternative

a. Ceftizoximeb. Cefotetan + Probenecid

11. Chlamydia11.1 Definition

11.2 Drugs11.2.1 Doxycycline

11.2.2 Tetracycline11.2.3 Azithromycin (Pregnant)

12. HIV/AIDS12.1 Definition

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12.2 Drugs

12.2.1 Reverse-Transcriptase inhibitorsa. Zidovudine

b. Didanosinec. Zalcitabine

12.2.2 Protease inhibitorsa. Saquinavir

b. Ritonavir12.2.3 Integrase Inhibitor

a. Raltegravir13. Carbuncle


13.2.1 Penicillin G13.2.2 Vancomycin

14. Scabies14.1 Definition

14.2 Drugs14.2.1 Permethrin cream

14.2.2 Lindane15. Schistosomiasis


15.2.1 Praziquantel16. Ascariasis


16.2.1 Albendazole16.2.2 Ivermectin

17. Enterobiasis17.1 Definition

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17.2 Drugs

17.2.1 Mebendazole17.2.2 Pyrantel pamoate

At the end of this unit the student will be able to:1.Identify the basic principles of cancer treatment

2.Discuss the cell cycle3. Identify the two drug classifications.

4. Identify appropriate drugs for different cancers and their side-effects.

5. Discuss the nursing management of patients undergoingchemotherapy.

UNIT II. ONCOLOGIC PHARMACOLOGY1.Cytotoxic antineoplastic drugs are usually classified in terms

of their mechanisms of action

1.1 alkylating agents ( Nitrogen mustard derivatives, nitrosoureas, platinum compounds)

1.2 and anti-metabolites

1.2.1 folic acid antagonist (eg, methotrexate),

1.2.2 purine antagonists (eg, mercaptopurine), and1.2.3 pyrimidineantagonists (eg, fluorouracil)

2. Cytotoxic antineoplastic drugs are usually classified in terms their sources2.1 Plant alkaloids

2.1.1 camptothecin (eg, topotecan),

2.1.2 podophyllotoxin (eg, etoposide),2..1.3 taxanes (eg, paclitaxel), and2.1.4 plants of the Vinca genus (eg, vincristine)

2.2 Anti-tumor antibiotics.2.2.1 Doxorubucin

2.2.2 Bleomycin3. Other drugs used in chemotherapy are immunostimulants, hormones, hormone inhibitors, a

cytoprotectants.

At the end of this unit the student will be able to:1. define biologic crisis and emergency.

2. Identify different emergency drugs for commonemergencies.

UNIT III. Drugs Used in Acute Biologic Crisis/Emergency Drugs1. Definition

2. Drugs Used in:2.1 Cardiac Arrythmias

2.2 Cerebrovascular Accident2.3 Acute Exacerbation of Bronchial Asthma

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2.4 Seizures

2.5 Pain2.6 Hypertensive Crisis

REFERENCES:

Allen, L, et al., Ansels Pharmaceutical Dosage Forms and Drug Delivery Systems, 8th edition, Lippincott, 2005

Clayton, B., et al., Basic Pharmacology for Nurses, 14th edition, Elsevier, Singapore, 2007Guitierrez, Kathleen, et al, Pharmacology for Nursing Practice, 1st ed., Mosby, 2003

Karch, Amy M., Focus on Nursing Pharmacology, 2nd edition, Lippincott, 2003.Kee, Joyce LeFever et al., Pharmacology A Nursing Process Approach, 2nd edition, W.B. Saunders Company, 2003

Lilley, L., et al., Pharmacology and the Nursing Process, 5th edition, Elsevier, Singapore, 2007Leda Mckenry & Evelyn Salerno. Pharmacology in Nursing. St. Louis: The CV Mosby Company, 1989

.

Drug HandbookSpringhouse, Nurses Drug Guide 2008, Lippincott, 2008Lippincotts Nursing Drug Guide, Lippincott, 2009

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Revised Pharma II May 2010psychCDONCOLOGY

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