PowerPoint-Prsentation

Bioptigen

Eric BucklandCo-Founder and CEO

EnFocus OCTThe Future of Surgical Imaging

1

Optical Coherence Tomography because Images MatterFounded 2004 Duke University (Joe Izatt)

2006 First 510(k) Dual Retina/Cornea OCT 2012 First 510(k) Pediatric Handheld OCT2015 First 510(k) Surgical Retrofit OCT

East Coast Angel FundedBrien Holden Vision InstituteNEI SBIR (2 Phase II, 1 FastTrack)50+ PatentsFrost & Sullivan Awards 2007 & 2015

Bioptigen Acquired by Leica Microsystems June 2015 because Images Matter

2

i

ii

iii

iv

Envisu C2300 Accelerates Intrasurgical OCT

PrePostImages courtesy Dr. Justis Ehlers

PrePost*Cleveland Clinic PIONEER Study

EnFocus made great by design

OCT

ObjectiiveOcularsMaximum Scan RangeCoaxial and TelecentricLatency-Free ImagingOCT Focus and DoFResolution: < 4 mmDepth: 2.5 mmENFOCUS Ultra HD OCTENFOCUS Ultra Deep OCTResolution: < 9 mmDepth: 11 mm*Depth and resolution as measured in tissue

EnFocus 4400 Ultra DeepFull Depth Anterior Imaging

Images courtesy Dr. Mathew Kurian, Narayana Nethralaya

EnFocus 4400 Ultra DeepRetinal Stem Cell ResearchImages courtesy Dr. Juan Amaral, NEINEI Stem Cell Research, porcine models

6

7

EnFocus 2300 High DefinitionMacular Hole Buckle PlacementImages courtesy Dr. Barbara Parolini, Brescia

7

Prepare corneaPrepare donor tissuePlace donor tissueSmooth, remove airEVALUATE

ABCDE

EnFocus 2300 High DefinitionDSAEK Cornea Transplant

What Will You DoDifferently With Your Surgical FieldEnFocus ?

Picture of EnFocus in use. 9