Restylane and Restylane (stylized) are registered trademarks of HA North American Sales AB. ©...

Restylane and Restylane (stylized) are registered trademarks of HA North American Sales AB. © 2004-2005 Medicis Aesthetics Holdings Inc. RES04089AR

Innovations in Aesthetic MedicineA Patient’s Guide to Restylane®


What happens as we age?

• Young skin is smooth and elastic

• As we age, skin loses volume and wrinkles appear

• This is due, in part, to skin losing its ability to produce enough of a naturally occurring substance called hyaluronic acid (HA)

Line

Wrinkle

Fold


What can be done?

• Dermal fillers with HA are an effective nonsurgical option– Fillers can fill in lines,

restore lost volume, and soften facial folds

– Fillers should be chosen by you and your doctor with care

For illustration purposes only; not actual results.


What defines an ideal filler?

• Natural-looking results

• Long-lasting, but not permanent

• Quick and easy treatment

• Cost-effective

• Non-animal in origin

• No allergy testing required*

• Minimal side effects

*Restylane contains traces of gram-positive bacterial proteins and is contraindicated for patients with allergies to such material.


Restylane® is an innovative dermal filler

• Restylane is a crystal-clear, non-animal, biodegradable HA gel

• First non-animal HA dermal filler approved for cosmetic use in the United States

• Gel is injected into the skin using a very fine needle to minimize discomfort

Note: Volume injected depends on patient, location, and degree of correction required. Photo courtesy of Q-Med.


Restylane® is natural and safe

• Used by dermatologists and plastic surgeons worldwide since 1996

• Contains HA, which is a natural part of human skin

• Free from animal proteins. This limits any risk of animal-based disease transmission or allergic reaction*

• Maintains an excellent safety profile– More than 1.5 million treatments worldwide

• Most clinical experience worldwide*Restylane contains traces of gram-positive bacterial proteins and is contraindicated for patients with allergies to such material.


Restylane® is long-lasting, not permanent

• Restylane effects generally last for about six months

• Because the face changes with age, permanent fillers may not look good over time

• Unlike permanent dermal fillers, your future needs can be re-evaluated when the treatment wears off

• With Restylane, follow-up treatments can be performed at any time


How do other fillers compare?

• Collagen– Bovine collagen is derived from animals (cows)

and requires an allergy test

– Restylane® lasts for about six months

• Other HA-based products– Restylane has the highest HA concentration

available (20 mg/mL)– Free from animal proteins - this limits any risk of

animal-based disease transmission or allergic reaction*



How does Botox® Cosmetic differ?

• Restylane® is a natural cosmetic filler and Botox Cosmetic is a drug that relaxes the underlying muscles that cause wrinkles

• Some physicians use Botox Cosmetic for the upper third of the face and Restylane for the lower third

• Patients have been very pleased after treatment with both products


What do Restylane® treatments cost?

• Restylane is a customized treatment based on your specific needs, so the cost will vary from patient to patient

• In general, the cost of a treatment is comparable to the cost of similar procedures

• However, because Restylane is long-lasting, it may be more economical over time


What should be done before treatment?

• There are things you can do before being treated with Restylane® to improve your experience and results– Avoid using St. John’s Wort, high doses of

vitamin E supplements, aspirin, or nonsteroidal anti-inflammatory medications, such as ibuprofen, for one week prior to treatment because these may increase bruising or bleeding at the injection site

– For patients prone to facial cold sores, treatment can cause a recurrence; a medication may be prescribed to reduce your risk


Treatment: Getting the look you desire

• Restylane® is injected directly into the skin using an ultra fine needle to minimize discomfort

• The procedure is short, simple, and convenient, and the results are nearly instantaneous


Will I feel discomfort?

• Many patients experience little to no discomfort during treatment, but everyone is different and certain parts of the face are more sensitive

• After the procedure, many patients felt that the pain was not as bad as expected


How to increase comfort during treatment

• A topical cream applied half an hour before treatment

• An injection of anesthesia, usually needed only when treating the sensitive area around the mouth

• Ice, which can be applied at the time of injection


• Avoid touching the area for at least six hours

• Keep a low profile that day– Postpone social engagements for one to two days– Avoid alcohol and vigorous exercise

• After your treatment, you might have some redness or swelling. This will normally last less than seven days

• Cold compresses can be applied immediately after treatment to reduce swelling

• Next morning, the area can be gently washed and light makeup applied

• Sunbathing and cold outdoor activities should be avoided until any redness or swelling disappear. If you are pregnant, breastfeeding, or under 18, you shouldn't use Restylane®

What to do after treatment


Restylane® Results


Restylane® Results

• Creates volume in the skin to smooth wrinkles and folds

• Produces an instantaneous, long-lasting, natural-looking enhancement

• Effects generally last for about six months


Restylane® Results

Before After

Individual results may vary.

Treatment of smile lines with 1 mL syringes


Restylane® is redefining satisfaction

• Provides immediate, long-lasting results

• Effects generally last for about six months

• No allergy testing required*

• More than 1.5 million treatments worldwide

• Excellent safety profile

• A simple, convenient procedure

Ask for Restylane by name!



Product Information

• Visit www.RestylaneUSA.com to register for exclusive offers and benefits!

• This site features – Restylane RewardsTM of up to $ 475– Facts about Restylane®

– Demonstrations and videos– Newsletters– Before-and-after photos– Complete product and safety information

Don’t miss out!

Restylane and Restylane (stylized) are registered trademarks of HA North American Sales AB. ©...

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