Resporite Elisa Fung Lindsay Kugler BeiXian Tang Gabriela Vargas Little Patients, Big Demands.
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Transcript of Resporite Elisa Fung Lindsay Kugler BeiXian Tang Gabriela Vargas Little Patients, Big Demands.
Resporite
Elisa FungLindsay Kugler
BeiXian TangGabriela Vargas
Little Patients, Big Demands
Motivation
• Mortality rate for children under the age of 5 in Africa is double that of the rest of the developing world– 166 deaths per 1000 children
• Respiratory distress syndrome (RDS) is the leading cause of death for underweight infants– Can be treated with ventilators
• Design a reliable, easy-to-use, and low-cost ventilator for use in the developing world
Design
Power source
Warning system/
system shut down
Tire pump
Pressure storage
chamber Valve 1: Regulates
pressure to 5psi
Valve 2: Regulates
pressure to 5cm H2O
Humidifier:Humidifies and
filters air
Nasal cannulae
Bubbling indicates system is working
Pressure, humidity, & temperature
sensors
Bike pump
Design
Midterm Goals
• Establish connections between components
• Test components individually and as a system• Determine length of time to fill & empty chamber• Set outgoing air pressure to 5-7 cmH2O• Determine flow rate• Humidify and filter air
Design Process
• Component 1: Air compressor– Attempt 1: Mattress pump– Attempt 2: Tire pump
• Component 2: Pressure storage chamber• Component 3: Valves
– Valve 1 (0-150 psi)– Valve 2 (0-2 psi)
• Component 4: Humidifier
Testing: Pressure Storage Chamber
• Purpose– Determine the time required to fill the pressure storage chamber.
• Results– Exponential relationship between time and pressure
Testing: Regulating Pressure
• Purpose– Determine if desired output pressure (5-7 cmH2O, or 0.07-0.10 psi)
• Results– Desired pressure achieved
0 cmH2O 5 cmH2O
Testing: Pressure Duration
• Purpose– Determine how long constant pressure will be observed at valve output with
varying chamber pressure
• Results– Determined that optimal starting pressure is 60 psi– Pressure in chamber does not last as long as desired
Time for Chamber Exhaustion
0
50
100
150
200
250
300
350
20 40 60 80Initial Pressure (psi)
Tim
e (s
econ
ds)
Time at 5 cmH2OTime until 0 psi
Testing: Humidifier
• Purpose– Determine effects of humidifier on system
• Results– Increases amount of time chamber can sustain desired pressure– Air is humidified
Time for Chamber Exhaustion with Humidifier
0
50
100
150
200
250
300
350
20 40 60Pressure (psi)
Tim
e (s
econ
ds)
Time at 5 cmH2OTime until 0 psi
Testing: Flow Rate
• Purpose– Determine flow rate at 5-7 cmH2O
• Results– Flow rate approximately 2.5 L/min
• Ideal flow rate is 5 L/min
Water (mL) Time (s)
100 2.07
200 4.34
300 7.13
400 9.88
500 12.34
Conclusion
• Macroscale Prototype– Major components of system connected– Pressure of 5-7 cmH2O achieved– Air flow rate of 2.5 L/min achieved– Humidified and purified air
Future Work
• Optimize flow rate for macroscale system• Incorporate temperature parameters• Backup system: bike pump, battery
• Microscale device to optimize current ventilator system– Electrical feedback system using LEDs and buzzer
Acknowledgments
• Dr. Gordana Vunjak-Novakovic• Dr. Samuel Sia• Dr. Helen Towers• Dr. Jen-Tien Wung• Yukkee Cheung• Keith Yeager• Sean Burgess• Rob Maidhof• Jonathan Belmont
Questions
?