Responsible Conduct of Research:IACUC &IBC

Office of Regulatory Research Compliance

To provide an overview of the Office of Regulatory Research Compliance and the role of

institutional review committees;

To describe the animal care and use and biosafety protections program;

To discuss the importance of responsible conduct of research involving animal

use and biosafety.

Objectives:

Regulatory Committee Chairs

To provide an overview of the Office of Regulatory Research Compliance and the role of institutional

review committees;

To describe the animal care and use, and biosafety protections program;

To discuss responsible conduct of research involving animal use and biosafety.

Objectives:

IACUC REVIEW PROCESS

Protocol Submission Flow

WHAT IS THE IACUC?• The IACUC (Institutional Animal Care and Use

Committee is the institutional review board that oversees research involving the use of animals.

• IACUC is charged with the duty to protect animals used in research, ensure proper care, and oversee animal research facilities.

• IACUC reviews all research protocols where animals are considered for use.

SPECIAL NOTE!

NO HUMAN SUBJECTS RESEARCH, ANIMAL

RESEARCH, OR RESEARCH INVOLVING BIOAGENTS AND RADIATION CAN BEGIN UNTIL IT HAS RECEIVED APPROVAL

BY AN INSTITUTIONAL REVIEW COMMITTEE.

HU IACUC PROTOCOL FLOWCHART (CONT.)

HU IACUC PROTOCOL FLOWCHART (CONT.)

IBC REVIEW PROCESS

Protocol Submission Flow

WHAT IS THE IBC?• The IBC (Institutional Biosafety Committee) is

the institutional review board charged with overseeing research involving biohazards, biological agents, radiation, human tissue, DNA, and other entities that may pose a risk to the welfare of the institution.

IBC Submission Flow

Questions and Answers

The Office of Regulatory Research Compliance

Location: The Office of Regulatory Research Compliance (ORRC)

1840 Seventh Street, NWHURB-1, Suite 309Washington, DC 20001202-865-8597 (Office)

Yonette F. Thomas, PhDAssociate Vice President for Research

Compliance