(RR

JH

S)

Research & Reviews

Journal of

Oncology & Hematology

STM JOURNALSScientific Technical Medical

(RRJoOH) eISSN: 2319-3387

Jan - April 2014

www.stmjournals.com

sCurrent Aspects of Nanomedicine for Cancer.

sEffectiveness of an Informational Booklet on Prevention of Cervical Cancer in

Terms of Knowledge and Attitude of Female College Students.

sEfficacy of Home Based Progressive Resistance Exercise Program Verses Aerobic

Exercise Program in Improving Quality of Life in Elderly Subjects.

sTreatment Planning Techniques in External Beam Photon Radiation Therapy.

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Research & Reviews: Journal of Oncology and Hematology

(ISSN: 2319-3387)

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Industrial Tribology Machine Dynamics & Maintenance

Engineering Centre (ITMMEC)

Indian Institute of Technology Delhi, India

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Alternative Energy Technology Laboratory,

Department of Physics,

Indian Institute of Technology, Chennai, India

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Varanasi, India

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Applied Chemistry, BIT Mesra,

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Gargi Asha Jha

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STM Journal (s) Advisory Board

Dr. Ashish RunthalaLecturer, Biological Sciences Group,

Birla Institute of Technology & Science, Pilani Rajasthan, India.

Dr. Baldev RajDistinguished Scientist & Director,

Indira Gandhi Centre for Atomic Research

(ICGAR)Kalpakkam, India.

Dr. Baskar KaliyamoorthyAssociate Professor, Department

of Civil Engineering National Institute of Technology Trichy, India.

Prof. Bankim Chandra RayProfessor and Head, Department of

Metallurgical and Materials Engineering National Institute of Technology,

Rourkela, India.

Prof.D. N. Rao Professor, Department of Biochemistry,

AIIMS, New Delhi, India.

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Medicine, Maulana Azad Medical College, New Delhi, India.

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Indian Institute of Technology, Madras, India.

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Dr. Priyavrat TharejaHead, Materials and Metallurgical

Engineering department, PEC University of Technology,

Chandigarh, India.

STM Journal (s) Advisory Board

Editorial Board

Prof. Satheesan BalasubramanianDirector, Professor and Head of

Department of Surgical Oncology Malabar Cancer Centre, Thlassery,

Kannur, India.

Professor Keechilat PavithranDepartment of Medicaloncology and

Hematology, Amrita Institute of Medical Sciences P.O. AIMS Ponekkara

Cochin, India.

Dr. Rakesh JalaliProfessor of Radiation Oncology

Convener, NeuroOncology Group, Tata Memorial Hospital Parel, Mumbai India.

Dr Dillip Kumar ParidaHead, Department of Oncology, Maw Diang

Diang, Shillong, Meghalaya, India.

Chinmay Kumar PandaDept. of Oncogene Regulation Chittaranjan National Cancer Institute, Kolkata, India.

Prof Thangarajan RajkumarProfessor and Head, Dept. of Molecular

Oncology,Cancer Institute (WIA), Adyar, Madras, India.

Dr. Pritha RayAssistant Professor and Principle

Investigator Tata Memorial Centre, India.

Dr. Lalit KumarDr. B.R. Ambedkar Institute-Rotary Cancer

Hospital, AIIMS Department of Medical Oncology, India.

Fayaz Ahmad MalikScientist Department of Cancer

Pharmacology Indian Institute of Integrative Medicine, India.

Ms Krishna P. GuptaCarcinogenesis Labratory,Indian Institute of

Toxicology Research,M.G.Marg, Lucknow, India.

Dr Arun ChaturvediSenior Consultant & Head of Surgical

Oncology Sahara India Medical Institute Ltd. Lucknow, India.

Dr. D.K. Vijaykumar Prof. & Head, Dept. of Surgical Oncology

Amrita Institute of Medical Sciences & Research CentrePonekkara P.O., Cochin

Kerala, India.

I take the privilege to present the hard copy compilation for the [Volume 3 Issue (1)] of Research &

Reviews: Journal of Oncology and Hematology. The intension of RRJoOH is to create an

atmosphere that stimulates creativeness, research and growth in the area of Oncology and

Hematology.

The development and growth of the mankind is the consequence of brilliant Research done by

eminent Scientists and Engineers in every field. RRJoOH provides an outlet for Research findings

and reviews in areas of Oncology and Hematology found to be relevant for National and

International recent developments & research initiative.

The aim and scope of the Journal is to provide an academic medium and an important reference for

the advancement and dissemination of Research results that support high level learning, teaching and

research in the domain of Oncology and Hematology.

Finally, I express my sincere gratitude and thanks to our Editorial/ Reviewer board and Authors for

their continued support and invaluable contributions and suggestions in the form of authoring write-

ups/ reviewing and providing constructive comments for the advancement of the journals. With

regards to their due continuous support and co-operation, we have been able to publish quality

Research/Reviews findings for our customers base.

I hope you will enjoy reading this issue and we welcome your feedback on any aspect of the Journal.

Dr. Archana Mehrotra

Director

STM Journals

Director's Desk

STM JOURNALS

1. Current Aspects of Nanomedicine for Cancer Markna J. H., Raval C. S., Shah N. A. 1

2. Effectiveness of an Informational Booklet on Prevention of Cervical Cancer in Terms of Knowledge and Attitude of Female College Students Sharma P., Kumari V., Bishnoi A. 5

3. Efficacy of Home Based Progressive Resistance Exercise Program Verses Aerobic Exercise Program in Improving Quality of Life in Elderly Subjects Improving Quality of Life in Elderly Subjects Choudhuri B., Patra P 11

4. Treatment Planning Techniques in External Beam Photon Radiation Therapy Michieka A 20

ContentsResearch & Reviews: Journal of Oncology and Hematology

RRJoOH (2014) 1-4 © STM Journals 2014. All Rights Reserved Page 1

Research & Reviews: Journal of Oncology and Hematology ISSN: 2319 -3387

Volume 3, Issue 1

www.stmjournals.com

Current Aspects of Nanomedicine for Cancer

Markna J. H.1*, Raval C. S.

1, Shah N. A.

2

1Department of Nanotechnology, V. V. P. Engineering College, Gujarat Technological University,

Rajkot-360005, India 2Department of Electronics, Saurashtra University, Rajkot-360005, India

Abstract Nanotechnology is an advanced as well as budding branch of the science. It involves the

studies of materials at the nano scale. It has demonstrated its enormous applications in

almost every discipline like in biotechnology, medicines, electronics, etc. Among its nanotechnology, when applied to medical specialties than it is called nanomedicines.

Nanomedicines are surprisingly effective in case of cancer. Nanomedicines provide

better drug delivery as well as more efficacious against tumor cells and with the help of

various nanoparticles better imaging of cancerous tissues can be possible. This article

briefly describes the current as well as future trends of nanomedicines in the case of cancers. It also pronounces benefits of these advanced medicines over the traditional

medicines.

Keywords: Nanotechnology, nanomedicines, cancer, nano particles, drug delivery

RRJoOH (2014) 5-10 © STM Journals 2014. All Rights Reserved Page 5

Research & Reviews: Journal of Oncology and Hematology ISSN: 2319 -3387

Volume 3, Issue 1

www.stmjournals.com

Effectiveness of an Informational Booklet on Prevention of

Cervical Cancer in Terms of Knowledge and Attitude of

Female College Students

Sharma P., Kumari V.*, Bishnoi A. M.M. College of Nursing, M.M. University, Mullana, Ambala, Haryana, India

Abstract Cancer of the uterine cervix is the leading cause of mortality and morbidity among

women worldwide. An experimental study was undertaken with the objectives to assess

and evaluate the effectiveness of an informational booklet on prevention of cervical cancer in terms of knowledge and attitude among female college students before and after

the administration of informational booklet. The research design adopted for the study was one-group pre-test post-test design. The sample comprised of 150 female college

students of M.M. Engineering College, Mullana which were selected by convenience

sampling. A knowledge questionnaire was used to assess knowledge of female college students regarding prevention of cervical cancer and 5-point. Attitude scale to assess

attitude of female college students regarding prevention of cervical cancer. Paired “t”

test was used to find out the significance of difference in mean pretest and posttest knowledge and attitude score. The findings suggest that the mean post test knowledge

score (25.9) was significantly higher than mean pre-test knowledge score (20.2) at p < 0.05. The subjects after exposure to the informational booklet gained a significantly

higher attitude score (96.56 versus 68.11 at p < .05.) The study concluded that

informational booklet was effective in enhancing knowledge as well as modifying the attitude of female college students on prevention of cervical cancer.

Keywords: Cervical cancer, informational booklet, knowledge and attitude

RRJoOH (2014) © STM Journals 2014. All Rights Reserved

Research & Reviews: Journal of Oncology and Hematology ISSN: 2319 -3387

Volume 3, Issue 1

www.stmjournals.com

Efficacy of Home Based Progressive Resistance Exercise

Program Verses Aerobic Exercise Program in Improving

Quality of Life in Elderly Subjects

Choudhuri B., Patra P.* Department of Physiotherapy, Dolphin (P.G.) Institute, Dehradun, India

Abstract The purpose of the present study is to compare the effectiveness of resistance training versus aerobic training for reduction of cancer related fatigue and improvement in

quality of life. A comparative study. Participants were selected from The Government Cancer Hospital, Agartala and few private cancer clinics. A total of 20 subjects were

recruited for the study on the basis of inclusion and exclusion criteria after signing the

informed consent form. MFSI-SF was used to measure cancer related fatigue and QOLS

was used to measure quality of life. The result of present study indicates that both

resistance and aerobic training improved the quality of life in subjects with CRF.

However, resistance trainings were more effective in both physical score (PS) and mental score (MS). The present study concluded that resistance training is more effective in

reducing fatigue in subjects with CRF as compared to aerobic exercise.

Keywords: cancer related fatigue (CRF), resisted training, aerobic training, quality

of life (QOL), multidimensional fatigue symptom inventory – short form (MFSI-SF),

quality of life scale (QOLS)

RRJoOH (2014) © STM Journals 2014. All Rights Reserved

Research & Reviews: Journal of Oncology and Hematology ISSN: 2319 -3387

Volume 3, Issue 1

www.stmjournals.com

Treatment Planning Techniques in External Beam Photon

Radiation Therapy

Michieka A.* Interdisciplinary Research, University of Nairobi, Nairobi, Kenya

Abstract Volumetric modulated radiation therapy (VMAT) is a modern treatment technique in

radiation therapy, and it delivers conformal radiation dose to the tumor while minimizing dose to the normal tissues. The beam delivery is done in the form of one or multiple arcs,

with gantry rotating around the treatment isocenter. A number of literature suggests that VMAT could be an attractive option to treat prostate cancer. However, there is no

consensus about which treatment technique produces better dosimetric results. In this

article, some of the factors which may influence the results of the studies are addressed. Furthermore, major dosimetric findings comparing different treatment planning

techniques for prostate cancer in external beam photon radiation therapy are

summarized.

Keywords: Treatment planning, VMAT, prostate cancer