Research and Innovation at Rutgers2010

RESEARCH AND INNOVATION AT RUTGERS

Welcome from the Vice President for Research and Graduate and Professional Education .......................... p.3

THE WIZARD OF MENLO PARK ......................................................................................................................... p.4

MAJOR CENTERS AND RESEARCH GROUPS ................................................................................................ p.5 Armed Forces Institute of Regenerative Medicine ................................................................................................ p.6 Institute of Marine and Coastal Sciences-Coastal Ocean Observatory Laboratory ......................................... p.6 Center for Transportation Safety, Security and Risk ............................................................................................. p.7 Wireless Information Network Laboratory............................................................................................................. p.7 Center for Discrete Mathematics and Theoretical Computer Science ................................................................ p.8 Rutgers University Cell and DNA Repository ........................................................................................................ p.9 Rutgers Helps Pharmaceutical Companies Move Towards Personalized Medicine ......................................... p.10 Crystallography Powerhouse ................................................................................................................................... p.10 Energy Storage Research Group; Coast to Coast on a Single Tank? ................................................................. p.11 Center for Molecular and Behavioral Neuroscience .............................................................................................p.11 Center for Advanced Infrastructure and Transportation ..................................................................................... p.12 Automated Nondestructive Evaluation and Rehabilitation System (ANDERS) for Bridge Decks ................. p.12 Putting Stimulus Funds to Work at Rutgers ........................................................................................................... p.13 A $9.6 Million Construction Grant for New Laboratory Creates Jobs ............................................................... p.13

NATIONAL INSTITUTES OF HEALTH CHALLENGE GRANTS .................................................................. p.14Dr. Linda Brzustowicz: Searching for the Roots of Autism .................................................................................. p.15Dr. Eileen White: Probing How Cancer Cells Work ............................................................................................ p.15 Dr. Ron Hart: A “Wild” Search for the Switches in Stem Cells ........................................................................... p.16 Dr. Danielle McCarthy: If Smokers Won’t Quit, Rutgers Researcher Won’t Either .......................................... p.16

MAJOR INSTRUMENTATION AWARDS ............................................................................................................ p.17 Ultra-High Resolution STEM Microscope ............................................................................................................. p.18Sharing a Valued Resource ....................................................................................................................................... p.18Imaging the Brain in Action .................................................................................................................................... p.18Fighting Disease with Computational and Structural Biology ........................................................................... p.19Looking Very Closely ............................................................................................................................................... p.19New Technology and New Uses for Carbon 14 ..................................................................................................... p.19

RUTGERS DIVERSITY PROGRAMS ................................................................................................................... p.20 STEM/Q-STEP ........................................................................................................................................................... p.20 The Rutgers Future Scholars Program Helps Area Students Succeed in College .............................................. p.21 Louis Stokes Alliance for Minority Participation .................................................................................................. p.21

K-12 PROGRAMS ..................................................................................................................................................... p.22 Science Preparation Alliance of Rutgers and Camden ......................................................................................... p.22Engineering Research Center on Structured Organic Particulate Systems ....................................................... p.22Institute of Marine and Coastal Sciences ............................................................................................................... p.22Center for Advanced Infrastructure and Transportation ..................................................................................... p.22Center for Discrete Mathematics and Theoretical Computer Science ............................................................... p.22Rutgers Science Explorer .......................................................................................................................................... p.22

BRIEFS ON RUTGERS RESEARCH PROGRAMS ............................................................................................. p.23Presidential Early Career Awards for Scientists and Engineers .......................................................................... p.23Magnetic Resonance Imaging as a Tool to Pinpoint Prostate Cancer ................................................................ p.24American Council of Learned Societies New Faculty Fellows ............................................................................ p.24National Institutes of Health Director’s Award ..................................................................................................... p.24 National Institutes of Health MERIT Awards ....................................................................................................... p.24

INDUSTRY – UNIVERSITY INTERFACE ........................................................................................................... p.26Professional Science Master’s Program ................................................................................................................... p.26National Science Foundation Industry/University Cooperative Research Centers .......................................... p.26

FUNDING TO SUPPORT RUTGERS GRADUATE EDUCATION .................................................................. p.28Graduate Assistance in Areas of National Need .................................................................................................... p.28Integrative Graduate Education and Research Training ...................................................................................... p.28Mellon Foundation Grant ......................................................................................................................................... p.28Institutional National Research Service Awards ................................................................................................... p.29

ENDING ON A MUSICAL NOTE: CONRAD HERWIG .................................................................................. p.29

APPENDICES - RUTGERS SPONSORED RESEARCH HIGHLIGHTS ......................................................... p.32

2

Welcome from the Vice President for Research and Graduate and Professional Education

I am pleased to present Research and Innovation at Rutgers. In the following pages we highlight the tech-nology, programs and competitive grant funding that make Rutgers, the State University of New Jersey, an internationally recognized research university known for excellent scholarship and teaching.

As the flagship research university of New Jersey with over 2,700 faculty, 37,000 undergraduates, and 13,000 graduate and professional students, the faculty at Rut-

gers includes 19 members of the National Academy of Sciences and 13 mem-bers of the National Academy of Engineering. Rutgers holds the distinction of being a member of the prestigious Association of American Universities.

In FY2010, Rutgers faculty were awarded four of the highly competitive NIH Challenge Grants, an impressive number for one university. Of 20,000 appli-cations, only several hundred were funded across the country.

Grant funding in total at Rutgers for FY2010 was $434 million, including over $329.5 million from the federal government.

Rutgers also garnered three out of only twenty Presidential Early Career Awards for Scientists and Engineers from the National Science Foundation (NSF), the highest honor bestowed by the United States government on pro-fessors in the early stages of their independent research careers. The recipi-ents were invited to the White House and recognized by President Obama.

The expanding research enterprise at Rutgers is a tribute to the excellence of the Rutgers research faculty, truly exemplifying “Jersey Roots, Global Reach.” I invite you to stay updated on Rutgers most recent grant awards, patents, and faculty start-ups at http://vpr.rutgers.edu.

Michael J. Pazzani, Ph.D.Vice President for Research and Graduate and Professional Education

Michael J. Pazzani, Ph.D. BiographyVice President for Research and Graduate and Professional Education

Dr. Michael J. Pazzani’s responsibilities at Rutgers include oversight of research and graduate education, research grants and sponsored programs, human subjects protection, laboratory and animal services, and technology commercialization. He is a Professor II of Computer Science, a member of the Rutgers University Center for Cognitive Science, and has a courtesy appointment in Library and Information Science. He has been funded by the National Science Foundation, the U.S. Department of Education, DARPA, AFOSR, ARO, and several companies including SAIC, Hughes Aircraft, Qualcomm, NYNEX, Websense, and Touchstone Software.

Prior to his appointment at Rutgers, Dr. Pazzani was the Director of the Information and Intelligent Systems Division at the National Science Foundation from 2002–2006 where he provided oversight for a research budget of $200M and helped to coordinate NSF’s homeland security research. He served as the Chair of Information and Computer Science at the University of California, Irvine. He also served as a member on the Board of Regents of the National Library of Medicine at the National Institutes of Health from 2003–2005.

Dr. Pazzani was a founder and CEO of AdaptiveInfo, has served on the board of directors of Combichem (NASDAQ: CCHM), now part of DuPont, and was a member of the scientific advisory board of several companies, including Pharsight Corporation (NASDAQ: PHST) and TripleHop Technologies, Inc. now part of Oracle.

3

THE WIZARD OF MENLO PARK

Dr. Paul Israel came east from California more than three decades ago to do research for a book on Thomas Alva Edison and the electric light. He soon became part of a massive project to document the contributions of the prolific inventor by combing through millions of his drawings, letters, business papers and research papers.

Today, Israel is the director and general editor of the Thomas A. Edison Papers project at Rutgers, and the group has just submitted its seventh volume to be published next year.

Edison did much of his most important research in New Jersey and was known as “the Wizard of Menlo Park.” He remains the most prolific inventor in American history – with an amazing 1,093

patents. He is famous for developing the phonograph, the motion picture camera, sound recording, and the modern light bulb, but he also invented numerous other devices that are less well known, such as the stock ticker, a mechanical vote recorder, and the electric car battery.

Israel says he has enjoyed learning about how Edison’s mind worked through his many years working with the project and his own research. “I’ve enjoyed it immensely,” he says. “It’s a lot of fun to rummage around in his brain and to see how he did things and to gain an appreciation of how sophisticated he was.”

Israel originally had a six-month contract to work on the Edison papers, but he ended up staying to work on his book and get his Ph.D. at Rutgers. His dissertation on the invention of the telegraph gave him insight into Edison’s many roles as an inventor and an entrepreneur.

In some ways Edison was an old-fashioned inventor, Israel explains, but in other ways he was very modern, and his Menlo Park lab is often seen as one of the first modern research and development laboratories. “He’s this transitional figure from the older side of invention to newer R&D,” Israel explains. Edison was modern in other ways as well and was a savvy marketer and promoter who knew how to use his fame as an inventor to promote his businesses and other inventions.

The upcoming volume coming out next year covers the period between 1883 and 1884 when Edison was working to build central electric stations in large towns and small cities in what was the beginning of the modern electric utility industry.

With some 5 million papers to comb through, there is no time to pause between volumes, so researchers are already at work on the next Edison volume which deals with the next period in Edison’s life when he settled down in West Orange, N.J. and built his new laboratory. The most recent volumes have been available digitally online, making it easy for researchers to use the documents.

“Part of our job is not just to understand what Edison did but also to make it accessible so people can use this in a variety of ways,” Israel explains.

The nationally renowned project is located on Rutgers’ Busch campus and is sponsored by Rutgers, the New Jersey Historical Commission, and the National Parks Service. The project received a $105,000 grant from the New Jersey Historical Commission this year and is in the second year of a two-year $300,000 grant from the National Endowment for the Humanities. It has a three-year $133,800 grant from the National Historic Publications and Records Commission.

Meanwhile, a revised version of Israel’s 1980 book on Edison’s invention of the light bulb retitled “Edison’s Electric Light: Biogra-phy of an Invention,” which he coauthored with Robert Friedel at the University of Maryland, was published last spring by Johns Hopkins University. It’s a slimmer volume that includes new insights about Edison’s famous invention and links to a website where readers can find many of the documents and illustrations referred to in the book.

“There are still a lot of people who see Edison as the old-fashioned, cut and dried inventor, and he’s much more sophisticated than that,” says Israel. “It’s been fascinating to understand how he does what he does.”

4

Innovation often requires contributions from a broad range

of specialties. At Rutgers University, there are over one hundred

research centers based on concepts that cross various fields of

science and technology. Collaboration at Rutgers is a major

driver for sponsored research, from addressing the Gulf oil

disaster, to creating biomaterials for face transplants and

addressing national security issues. Rutgers researchers and

faculty generate ideas for solutions to problems.

A sampling of the centers follows.

MAJOR CENTERS AND RESEARCH GROUPS

5

Armed Forces Institute of Regenerative Medicine; Rutgers/Cleveland Clinic Consortium Attracts Global Recognition for First Face Transplant Surgery in the United States

Although she may never have stepped foot in New Jersey, Con-nie Culp, the recipient of the first face transplant surgery in the United States, owes a lot to the work of the New Jersey Center for Biomaterials located at Rutgers University.

Many of the materials used in the surgery were designed by a consortium led by Dr. Joachim Kohn, Board of Governors Pro-fessor of Chemistry and Chem-ical Biology and Director of the New Jersey Center for Biomate-rials.

Ms. Culp, who underwent the final surgery in July of 2010, initially underwent 22 hours of surgery in December 2008 by a

team of doctors who were part of the Armed Forces Institute of Regenerative Medicine (AFIRM) program.

The Rutgers-Cleveland Clinic Consortium was formed by the New Jersey Center for Biomaterials in collaboration with the Cleveland Clinic, after Dr. Kohn was awarded a 5-year $42.5 million grant by the U.S. Army Medical Research and Material Command, in conjunction with the Office of Naval Research, the National Institutes of Health, the Air Force and the Depart-ment of Veterans Affairs for the development of new battlefield injury therapies and medical materials.

Dr. Kohn’s expertise in the field has also lead to the creation of new biomaterials designed to accelerate the growth of damaged tissue. Read more at http://www.njbiomaterials.org/web/index.php.

Institute Of Marine And Coastal Sciences- Coastal Ocean Observatory Laboratory; Helping Out Remotely with the Gulf Oil Disaster

When the Deep Water Horizon oil rig exploded off the Gulf Coast in April spewing thousands of gallons of oil a day into the water, the Rutgers Institute of Marine & Coastal Sciences (IMCS) sent two remote-controlled gliders to patrol the waters off the Florida coast.

The spill became the worst oil disaster in history dumping more than 200 million gallons of oil into the ocean over a five-month

period, and federal officials from the National Oceanic and At-mospheric Administration asked Rutgers Coastal Ocean Obser-vatory Lab (COOL) to send the gliders to try to predict where the oil would wash ashore.

The research gliders are small robotic submarines that can be programmed for various tasks. In this case, they measured the currents for ocean forecasts and the salinity and water tempera-tures so NOAA could predict where the oil would go. It also took readings on plant life to be analyzed later.

“We weren’t down on the ground with all the folks who were down there, but we were participating and we could get our stu-dents participating right from New Jersey,” says Josh Kohut, an oceanography professor who was involved with the Gulf moni-toring.

Kohut, who is a member of the New Jersey Department of En-vironmental Protection’s oil spill task force, says the oil from the spill has dissipated but he still worries about the impact. “A lot of the impact we see from the oil we may never see with our own eyes,” Kohut says. “There’s potential impacts within the ocean itself we’ll never see on cameras.”

Rutgers has 22 of the 7-foot, 100-pound gliders that look like rockets with fins but glide slowly along at just half a mile an hour. They have small batteries and they work by taking water in the nose of the gliders that pushes them down and then lets the water out to come up again. Every six hours they come to the surface, stick their tail out of the water, and literally call home with an update on their status and the data they’ve collected.

Those calls are taken in a room at the IMCS building on Rutgers’ Cook Campus where the gliders’ progress through the ocean is charted on six huge TV screens that, Kohut says, is “kind of like our Houston.” In another room, technicians program the glid-ers for their next missions.

A glider is currently moving up and down the New Jersey Coast from Sandy Hook to Cape May where it is collecting data about the ocean off the New Jersey Coast and sending the information to Stevens Institute of Technology, which uses the information for daily ocean forecasts used by the Coast Guard.

These gliders not only measure temperature and salinity but also how much dissolved oxygen there is in the water. When there is too much algae or bacteria, the oxygen level goes down so it’s a good indicator of the water quality. The measurements could be used as base measurements if there is ever an environ-mental crisis off New Jersey’s coast.

Last year, COOL sent a glider that Rutgers President, Richard L. McCormick, dubbed the “Scarlet Knight” across the Atlantic Ocean. This winter, the gliders will go even further afield with projects in the Antarctic aimed at measuring global warming.

Gliders have already been sent to the Antarctic for different

6

projects. One of those projects will use the gliders to measure whether phytoplankton, the base of the food chain, is decreas-ing along the Antarctic Peninsula.

Researchers will also take part in a study funded by both NASA and the NSF that will use satellite data and data from the glid-ers to document the reasons behind the decline of Adeline pen-guins from about 15,000 pairs in the mid 1970s to about 3,000 breeding pairs today. The penguins have been moving south as they lose their habitat, and the project will tag them to trace them while the gliders will be used to map their habitat.

Kohut is also working on a project in the Antarctica that will begin in February to study the role of iron in the growth of phy-toplankton, the base of the food chain. His hypothesis is that warmer water plays a role in delivering the iron.

Still another project has been monitoring water temperature and other conditions off the Antarctic Peninsula since the 1980s that may offer some clues about global warming. “Antarctica ac-celerated changes are happening so quickly,” Kohut explains. “If we concentrate our studies down there, we might learn things that we can apply to other parts of the world that might not be changing as rapidly.”

Center for Transportation Safety, Security and Risk

After President Barack Obama announced plans for a network of high speed rail lines and improvements to Amtrak’s Northeast Corridor rail line, the need for making sure the nation’s transpor-tation systems are safe and secure became greater than ever.

Transit security is particularly important for New Jersey where so many people and companies depend on the transit system.

The Bloustein School of Planning and Public Policy’s Center for Transportation Safety, Security and Risk (CTSSR) is focused on doing just that. Funded by two grants from the federal Depart-ment of Homeland Security totaling $1.5 million, the center is looking at nine different security issues. The topics range from preparing for a possible chemical or biological weapons attack to training school bus drivers in how to communicate effectively with the children they are transporting during a crisis.

“It’s a different kind of challenge because it’s right here, right in our backyard here and in the area I live in and we all live in,” says Michael Greenberg, the director of the center.

Rutgers is one of seven institutions comprising the National Transportation Security Center of Excellence, and the CTSSR works with the Na-

tional Transit Institute to evaluate transportation security in the U.S. and looks at issues from preparing for a possible chemical

or biological weapon attack to training school bus drivers.

“The whole idea is not to sit around and wait. The whole idea is to figure out what might occur,” explains Greenberg, “and then introduce ways in which the event could be completely stopped or if they occur could be completely less, and make sure the system bounces back as soon as possible. That’s really what cuts across all of this work, to mitigate and make resilient.”

One of the center’s programs is aimed at increasing rail security by building a risk-based model called “A Smart Model for Rail Corridor Resilience” that will come up with ways to avoid a di-saster or attack on the rail lines and come up with the best ways to recover from such events if they do occur.

Other projects include training agencies to support populations with limited English during a crisis, training bus drivers to re-spond to suspicious behavior to stop potential terrorist attacks, training transit employees to communicate in a crisis and de-veloping a computer game that trains transit employees to deal with security situations.

Wireless Information Network Laboratory; Preparing The Internet of The Future

In the not so distant future, the Internet will go where you go. When you get into your car, for example, the Internet might be built into your car so that it can tell you and other cars when there’s a traffic jam ahead or send instant commands to other cars to avoid a collision.

Dr. Dipankar Raychaudhuri, the Di-rector of Rutgers’ WINLAB, knows this may sound a little bit like science fiction, but he says the technology is happening already. “This has a very futuristic feel to it,” he admits. “Grad-ually you’ll see things happen.”

He explains that the future of the Internet is a mobile Internet that no longer exists in a virtual world but is built into the envi-ronment, and WINLAB will be one of the leaders in developing the Internet of the future with the help of a three-year, $7.5 mil-lion grant from the National Science Foundation.

WINLAB is leading a group of nine universities on a “Mobility-First” team on the NSF’s Future Internet Architecture program that began in September. “It’s very exciting,” says Raychaudhuri. “This is one of those projects where technology meets society , and it has a lot of interesting dimensions.”

There are currently 4 billion cell phones in use worldwide, and in the next five years Internet-connected cell phones are expect-

7

ed to vastly outnumber wired devices like traditional personal computers using Internet servers.

Raychaudhuri explains that the Internet today allows access only through a server that provides access at your home, office or even a local coffee shop and requires you to have an Inter-net protocol or IP address. Cell phones, on the other hand, are able to reach you wherever you go, but they also have certain problems, like losing the signal in certain places. “We’re trying to merge the good qualities of cellular with the Internet,” Ray-chaudhuri says.

The next generation Internet will provide information much more quickly to enable you to find someone on the Internet al-most instantly, for example, or to be able to find out where the nearest Starbucks is without logging in to an Internet server.

The three-year project will design the network, evaluate its per-formance, come up with a large-scale prototype and do trials trying out the system in the real world. The research team will have to address numerous technical issues for a mobile Internet system, such as how to ensure reliable network connections de-spite variations in the strength and quality of wireless signals.

Because the future Internet will be able to go anywhere, it would need to constantly assign new network addresses to users while still ensuring the network’s security and protecting users’ pri-vacy.

WINLAB began looking at the future of the Internet through an earlier NSF project called FIND (Future Internet Design), which started in 2006. WINLAB faculty members, including Drs. Raychaudhuri, Marco Gruteser and Roy D. Yates, received three separate grants to study various aspects of Internet design such as location-aware geographic services, cognitive networks and mobile content delivery.

WINLAB, which is located on Route 1 in North Brunswick, has been a key participant since 2005 in the NSF program called Global Environment for Network Innovation or GENI. The GENI project is focused on developing a global scale, experi-mental infrastructure that can be used for research on the archi-tecture, design and protocols for the Future Internet project.

The GENI project uses WINLAB’s ORBIT laboratory to test some of the technology, and WINLAB is collaborating with several different institutions, including Stanford, the University of Massachusetts, UCLA and the Polytechnic Institute of New York University, to build a wireless Internet infrastructure that would be used on several campuses.

ORBIT was funded with an initial grant of $6 million in 2003, and it became operational as a community testbed in 2005. It

received an additional $1.5 million grant in 2007 and a $2 mil-lion grant for major equipment upgrades in 2009. The combined funding has made Rutgers one of the best-equipped campuses in the nation for Internet research.

ORBIT is an open, fully programmable testbed that is set up with 400 radio transmitters that can be programmed to emu-late various conditions for wireless technology and new mobile services. For example, the laboratory can be programmed to simulate wireless devices being used in cars on a highway. More than 250 university and company research groups have used the ORBIT laboratory worldwide to test new wireless technology.

Rutgers WINLAB has been a leader in wireless technology since it was first established in 1989 as a university and industry co-operative research center. In that time, it has made several im-portant contributions to mobile computing, high-speed modem design, radio resource management and network architectures and protocols.

WINLAB has also educated future scientists and engineers in this growing field. Some 140 students have graduated with M.S. or Ph.D.s in wireless technology since it began.

The research center gets about 80 percent of its funding from federal grants but also has some 15 industry sponsors, including Erikson, Qualcomm, Alcatel-Lucent, and Toyota.

Center for Discrete Mathematics and Theoretical Computer Science; Using Mathematics for National Security

The Center for Discrete Mathematics and Theoretical Computer Science, or DIMACS, has been deeply involved in the effort to protect our nation’s security since the September 11th attacks.

DIMACS is home to the Command, Control and Interoperabil-ity Center for Advanced Data Analysis (CCICADA), a center of excellence established by the Department of Homeland Security (DHS) in 2009 charged with data analysis for homeland secu-rity. It’s part of the DHS Center of Excellence in Command, Control and Interoperability that also includes Purdue Univer-sity, which is in charge of the visualization sciences.

“This is important because it gives Rutgers a major national vis-ibility as an important contributor to homeland security,” ex-plains Dr. Fred Roberts, the Director of DIMACS.

DHS said the Center of Excellence “will create the scientific basis and enduring technologies needed to analyze massive amounts of information from multiple sources to more reliably detect threats to the security of the nation and its infrastructures and to the health and welfare of its populace.”

Rutgers and its 13 partner organizations that are part of CCICA-

8

DA have a six-year grant from the DHS of $2.5 million a year to develop a new generation of computational tools for homeland security that will analyze massive amounts of information from books, newspapers, reports, blogs, images, geospatial data, sen-sor readings, and audio and video streams.

DIMACS was founded in 1989 with Rutgers’ partners, Prince-ton University, and two telecommunications companies, AT&T Laboratories and Bellcore, with a $22 million grant from the National Science Foundation to establish a Science and Tech-nology Center. It soon led the way in showing how mathemati-cal solutions could be applied to a variety of subjects, including science, engineering, the environment, economics, agriculture and public policy.

CCICADA is working on several projects, some of which build on work that was done at DIMACS beginning shortly after the September 11 attacks, including looking at ways to moni-tor email messages and to find clusters of messages during cri-ses, ways to identify the authors of email messages and other documents, infectious diseases, locating sensors such as those to detect bioterrorist attacks, finding ways to defend the cy-ber network from attack, and developing “crime maps” to help law enforcement with allocation or reallocation of human and monetary resources.

“Dealing with massive amounts of data gets us very much in-volved in the entire homeland security area,” says Roberts.

CCICADA is involved in other crucial national security areas as well. It received a grant of $561,000 from DHS that will exam-ine the trade-off between security and economic activity. “Our piece of it is really to try to use data analysis methods and math-ematical modeling methods to assess the risks associated with investing more or less in security and to look at the connections between making more investments and whether that will hurt economic activity,” Roberts explained.

Researchers will look at the intersection between commerce and security, with a focus on the World Trade Center site in Lower Manhattan, and the Port of Los Angeles/Long Beach, as well as other sites that might pose national security risks.

Another project CCICADA is working on is a $2 million grant that began last year to establish a domestic nuclear detection of-fice. It will develop algorithmic methods for detecting the prob-ability there are nuclear materials in containers at ports and will look at a lot of data such as x-ray data and launching data. One goal is to decide what other tests can be performed to detect nuclear materials. The project will also look at the possibility of having moving nuclear detectors at borders and ports and other places by attaching the detectors to police cars and taxicabs.

Researchers at CCICADA are also working on a project funded with a $250,000 grant from DHS that will prepare simulations for sports stadiums in the event of an emergency. The project will look at the behavioral aspects of crowd behavior in evacuations at

stadiums such as the New Jersey’s Meadowland Stadium. The DHS is also funding fellowships for six Rutgers graduate students with a new grant of $500,000 and two previous grants of $400,000 and $500,000 respectively.

In addition to homeland security, DIMACS has led the way in computational epidemiology through grants that ended this year that got DIMACS into the emerging fields of biosurveillance us-ing mathematical models to predict the spread of disease. Their research has led them into new programs and collaborations, like a biomathematics initiative with Africa, through a $940,000 grant from the National Science Foundation.

The project on epidemiology led DIMACS into work on climate change. DIMACS is looking at the possible health effects of se-vere temperatures caused by global warming. It is also investi-gating potential security threats due to climate change through a $92,000 grant from the NSF.

Rutgers University Cell and DNA Repository; Utilized Worldwide to Tackle Research on Global Diseases and Disorders

The Rutgers University Cell & DNA Repository (RUCDR) is the world’s leading repository of sam-ples supporting genetics research on the leading causes of complex diseases, including autism, alco-holism, schizophrenia, bipolar dis-orders and drug addiction, as well as diabetes and kidney disease. Led by Jay Tischfield, Ph.D., RUCDR

has aggressively pursued funding for many years and has con-sistently topped the funding list at Rutgers. The repository has won close to $200 million in support since it started and recent-ly was awarded a $9.6 million grant from NIH stimulus funds to expand its space for storing samples.

Housed on the Busch Campus of Rutgers, the State University of New Jersey, RUCDR is part of the Rutgers Department of Genetics and the Human Genetics Institute of New Jersey. It is the principal provider of resources such as DNA, RNA and cell lines to hundreds of research laboratories worldwide.

Dr. Tischfield estimates that researchers have used RUCDR samples to support research resulting in more than 1,000 papers since he first began the center about 20 years ago, and he puts the value of that research in the billions of dollars.

9

The RUCDR facility has distributed nearly 1 million DNA and other biological samples over the past decade for researchers as far away as Central America, Europe, Australia, and Taiwan.

A study on Tourette Syndrome, co-authored by Drs. Tischfield and Gary Heinman, found the gene mutation in one family in which the father and all eight children have the neurological disorder, which can cause body, facial and verbal tics. Samples for the disease came from the New Jersey Center for Tourette Syndrome Sharing Repository, which is housed at the RUCDR. The study was published in the New England Journal of Medi-cine in May, 2010.

Rutgers Helps Pharmaceutical Companies Move Towards Personalized Medicine

With all of the debate about the high cost of pharmaceutical treatments, one Rutgers University center is helping. The Na-tional Science Foundation (NSF) Engineering Research Center for Structure Organic Particulate Systems (C-SOPS) located at Rutgers University and led by Fernando Muzzio, Ph.D. is devel-oping new and novel ways for drug manufacturers to produce specialized medications while reducing the cost of production. Drug treatments, such as those designed for cancer patients or patients with rare diseases, can top $100,000 a year.

“We started working on the topic of continuous and specialized manufacturing a few years ago,” explains Dr. Muzzio. “When we started, the industry was using very blunt instruments to produce very large quantities of medications; however, with the processes designed and implemented at C-SOPS, drug manu-facturers can reduce the size needed to run a production se-quence reducing the overall cost and making it more practical to move towards personalized medicine.”

Recent research has indicated that the pharmaceutical industry may be wasting in excess of $50 billion a year in inefficiencies in manufacturing. These reports cite cycle time, deviations and yields, which all are directly correlated to the eventual cost that is transferred to the customer. New methods are being developed at C-SOPS to reduce these costs, which can be re-invested into future research & development for the individual companies.

“There is a huge demand for smaller and more versatile manu-facturing by big pharma,” said Dr. Muzzio. “We are continuing to expand their capabilities for manufacturing by developing new systems, materials and techniques that resemble simple printing. Our mission is to develop methods that can make per-sonalized medicine more practical for the industry.”

According to Dr. Muzzio, C-SOPS is also a very diverse Uni-versity Center where students, researchers and faculty are be-

tween 30-35 percent minority and approximately 30-40 percent female. This diverse workforce allows C-SOPS to be very cre-ative in their thinking, according to Dr. Muzzio, which is a key reason for C-SOPS continued success.

The mission of C-SOPS is to 1) develop a scientific foundation for the optimal design of structured organic particulate systems, 2) develop science and engineering methods for designing, scal-ing, optimizing and controlling relevant manufacturing pro-cesses, 3) establish effective educational and technology transfer vehicles and 4) establish effective mechanisms for the inclusion and participation of minorities and women at all levels.

Dr. Muzzio concludes, “If we can lower the cost of pharmaceuti-cal manufacturing and make it more financially achievable for advances like personalized medicine and if we can do this on a global scale, then it’s going to be something available every-where and to everyone and then it is worth the effort.”

Crystallography Powerhouse; Rutgers Protein Data Bank to Move into New $55 Million Center for Integrative Proteomics Technologies on Busch Campus

The new $55 million building on Busch Campus called the Cen-ter for Integrative Proteomics Technologies (CIPT) will be the new home for the world-wide archive of nearly 66,000 3-D mole-cules and nucleic acids structures, among other research groups.

Today, the Rutgers Protein Data Bank (PDB) attracts nearly 20 million file downloads each month from scientists around the world. Led by Dr. Helen Berman, the Rutgers Board of Gover-nors Professor of Chemistry and Director of the Rutgers PDB, the repository was created by Dr. Berman and several colleagues to facilitate a central resource for protein crystallographers.

10

The PDB’s lead funding resource is the National Science Foun-dation which awarded Dr. Berman a $30 million contract. The National Institutes of Health and the U.S. Department of Energy also provide funding support. The CIPT facility will include over 70,000 square feet of lab space and it will house nearly 14 research groups working in both experimental and computational pro-teomics, structural biology, and computational biology.

Established in 1971 with seven structures at Brookhaven Na-tional Laboratory, the archive is managed by a consortium called the worldwide Protein Data Bank (wwPDB). The RCSB (Research Collaboratory for Structural Bioinformatics) PDB, based in the Department of Chemistry and Chemical Biology at Rutgers, and the University of California-San Diego (UCSD) Skaggs School of Pharmacy and Pharmaceutical Sciences, is re-sponsible for releasing PDB entries into the archive after they have been reviewed and annotated.

The archive receives approximately 25 new structures from scientists each day. Users include structural biologists, com-putational biologists, biochemists, and molecular biologists in academia, government and industry as well as educators and students. The PDB presents a comprehensive website and da-tabase that lets users search, analyze, and visualize the struc-tures of biological macromolecules and their relationships to sequence, function and disease.

The unique aspect of wwPDB is that structural information is included (other protein data banks have information about se-quence and function only). The crystal structure is important in order to understand how molecules fit together which is use-ful in rational drug design.

Energy Storage Research Group: Coast To Coast on a Single Tank? – Pushing the Envelope with Battery Technologies

During the next 10 years, gas pumps may just be a memory of the industrial revolution and fodder for history textbooks. That is if Glenn Amatucci, Ph.D. and the Energy Storage Research Group (ESRG), housed in a 26,000-square-foot facility at the Rutgers Technology Center II in North Brunswick, N.J., have anything to say about it. The ESRG’s cutting-edge research into key atom-ic-scale processes, governing electrode function in rechargeable batteries, and their ability to develop novel characterization and theoretical tools will drastically improve the functionality of tomorrow’s batteries. Energy storage and rechargeable bat-teries are important to the automotive industry and the next generation of low-emission designed vehicles, ESRG will be the architects designing the next generation of batteries.

The global economic concerns over oil volatility, gasoline short-ages and environmental change have prompted a cross indus-try emphasis to commercialize new and affordable methods for battery design, manufacturing and energy storage. Amatucci

and the team of researchers in the ESRG are part of a larger pro-gram called the Northeastern Center for Chemical Energy Stor-age (NECCES), which is a collaboration among SUNY Stony Brook, Rutgers, SUNY Binghamton, Massachusetts Institute of Technology, University of California San Diego, the University of Michigan Ann Arbor and the Lawrence Berkley, Argonne and Brookhaven national laboratories. It has recently received $17 million over 5 years from the United States Department of En-ergy’s Energy Frontier Research Center (EFRC) Program.

Center for Molecular and Behavioral Neuroscience

The Center for Molecular and Behavioral Neuroscience (CMBN) located at Rutgers University - Newark was established by the Board of Governors of Rutgers University in 1985. Designed by then Rutgers Newark Provost Norman Samuels, the CMBN was the integration of the departments of chemistry, biology, and psychology into a center for neuroscience to integrate molecu-lar and behavioral neuroscience. Samuels engaged Paula Tal-lal, Ph.D. and Ian Creese, Ph.D. to lead the efforts, and both faculty are co-directors of CMBN. Overall CMBN brought in $4,457,059 in funding in FY 2010 from various sources, includ-ing the National Institutes of Health and the National Science Foundation.

The CMBN houses 13 research teams that are at the forefront of neuroscience research. The researchers of tomorrow are being trained at the CMBN in the graduate program in Integrative Neuroscience and introductory courses and summer intern-ships for undergraduate students.

By attracting both external funding and public interest through research, the CMBN continues to build the various strengths of behavior and neurobiological research among the 13 member faculty. CMBN has a mission to conduct leading edge research and to also teach the next generation of researchers. The goal of

11

the Graduate Program in Behavioral and Neural Science (BNS), according to their mission, “is to provide both outstanding training across the subdisciplines of neuroscience as well as to provide intensive training within one area of focus so that our graduates will be prepared for careers as academicians, educa-tors and research scientists.”

There are currently 33 Ph.D. candidates and 18 post-doctoral students in the program who assist the 13-member faculty in their continued research. In addition to the Ph.D. program, CMBN also offers introductory courses and summer intern-ships for undergraduate students enrolled at Rutgers.

Center for Advanced Infrastructure and Transportation

Rutgers’ Center for Advanced Infrastructure and Transporta-tion (CAIT) is engaged in research, education, and technology transfer activities that address every aspect of transportation and infrastructure. CAIT is a Tier I University Transportation Center (UTC), one of an elite group of academic research in-stitutions sanctioned and supported by the U.S. Department of Transportation, led by Professor Ali Maher.

The center partners with government, industry, and academia to solve mounting infrastructure challenges, advance state-of-the-art technologies, and prepare the next generation of trans-portation professionals.

Addressing the broad spectrum of multimodal transportation, CAIT is helping to meet the need for safe, efficient, and environ-mentally sound movement of people and goods in our nation and beyond.

In April 2008, CAIT was awarded a $25.5 million competitive con-tract to lead the Long-Term Bridge Performance (LTBP) program, an initiative of the Federal Highway Administration (FHWA).

LTBP is envisioned as a 20-year comprehensive examination of our nation’s “workhorse” highway bridges—structures we drive on every day—which include what many people commonly think of as elevated roadways. The study hopes to provide a more detailed and timely picture of bridge health, improve our knowledge of bridge performance, and ultimately promote the safety, mobility, longevity, and reliability of our nation’s highway transportation assets.

Over a five-year period, the CAIT team will inspect, document, evaluate and periodically monitor a representative sample of bridges nationwide, taking advantage of advanced condition monitoring technologies in addition to detailed visual inspec-tions. They will examine bridges holistically, looking at all of

the factors and forces that affect how bridges perform—in other words how they “behave”—over time. This includes monitoring environment and climate, traffic, materials, and design.

The high-quality data gathered in the process and the subse-quent data analysis and mining will lead to improved life-cycle cost and predictive models, better understanding of bridge dete-rioration, and more effective maintenance and repair strategies. LTBP results should also support improved design methods and bridge preservation practices and help develop the next genera-tion of bridges and bridge management systems.

Automated Nondestructive Evaluation and Rehabilitation System (ANDERS) for Bridge Decks

In December 2009, CAIT’s Infrastructure Condition Monitor-ing Program (ICMP) was awarded a U.S. Commerce Depart-ment grant that will support a $17.9 million project aimed at improving bridge maintenance and safety. Funding came from the National Institute of Standards and Technology (NIST) un-der its Technology Innovation Program (TIP). TIP is a merit-based, competitive program that provides cost-shared funding for innovative, high-risk research in technologies that address critical national needs.

The ICMP team at CAIT identified a great need for advances in condition evaluation and early-intervention repairs for bridge decks. Between 50 and 85 percent of bridge maintenance costs go toward repair or replacement of decks. The need for new as-sessment and repair methods was confirmed by interviews with bridge engineers across the country done in connection with CAIT’s work on the Federal Highway Administration (FHWA) Long-Term Bridge Performance Program.

The NIST-TIP project is formally known as the Automated Nondestructive Evaluation and Rehabilitation System (AN-DERS) for Bridge Decks. A quantitative condition assessment component of ANDERS will use nondestructive evaluation (NDE) technologies to identify and characterize localized dete-rioration. Expectation is that this data will also help shed light on how deterioration affects the bridge’s overall performance. A second component of the ANDERS project will develop materi-als and robotic equipment for deployment of early deterioration stage repairs.

ANDERS is a joint-venture project with partners from indus-try and academia including MALÅ GeoScience USA, Pennoni Associates Inc., PD-LD, Inc., Drexel University, University of Texas at Austin, and Georgia Institute of Technology.

12

Putting Stimulus Funds to Work at Rutgers

“Our investments in innovation are creating jobs, creating new industries, making existing industries more competitive, and in the process, they’re driving down costs for new technologies that are badly needed, and helping our nation reassert our place as the world’s center for inventors and entrepreneurs.”

Vice President Joe Biden in an Aug. 24, 2010 speech announcing the Recovery Act Innovation Report.

The White House cited a groundbreaking project to build the most advanced electron microscope in the world at Rutgers as an example of projects funded by President Obama’s stimulus package that are transforming the U.S. economy and helping to create jobs.

The new microscope is one of numerous innovative research projects at Rutgers that are leading the way to new discover-ies in technology, medicine and education through funds from the $787 billion American Recovery and Reinvestment Act (ARRA).

Rutgers has received $52 million from the stimulus funds for a wide range of projects that have been used to support jobs and research, including $28.5 million from the NIH for research into cancer, autism, obesity and other serious health problems, and $12.9 million from NSF.

One big project that is putting people to work in New Jersey is funded by a $9.6 million award from NIH stimulus funds to create new storage space for samples at the Rutgers University Cell and DNA Repository. More than 100 jobs were created.

Not only have the ARRA funds helped create jobs at Rutgers, ARRA funds have been used to train young people for jobs in today’s high-tech competitive economy through programs like the Rutgers’ new Professional Science Master’s program. Funded by NSF with ARRA funds, the PSM offers advanced courses in business as well as science, math, engineering and technology.

Rutgers’ WINLAB used stimulus funding to upgrade its experi-mental campus network infrastructure as part of its Global En-vironment for Network Innovation (GENI) and which in turn helped Rutgers get a $7.5 million grant from the National Science Foundation to develop plans for the future mobile Internet.

A $9.6 Million Construction Grant for New Laboratory Creates Jobs

The Rutgers University Cell and DNA Repository (RUCDR) received a $9.6 million grant that will be used to expand its fa-cility on the Busch Campus by creating a new robotics-driven laboratory on the second floor of Nelson Biological Laboratory on Busch Campus.

“I’m very excited,” said Jay Tischfield, the Director of the RUCDR. “This is the first time we’ve gotten construction fund-ing and one of the few times that Rutgers has.”

Rutgers was one of 146 institutions to receive construction grants from a $1 billion fund to construct and improve scientific laboratories throughout the United States.

“These Recovery Act dollars will provide state-of-the-art facili-ties in hundreds of researchers to conduct cutting-edge science with the latest technologies,” said NIH Director Francis S. Col-lins when the grants were announced. “At the same time, they will create job opportunities nationwide.”

Tischfield says the RUCDR has outgrown its current facilities for the past few years and the workload has doubled every two to three years. The robots at the new laboratory will help process hundreds of thousands of samples.

He estimates that the laboratory will hold 30 employees and will allow the RUCDR to hire an additional 20 people and the construction would provide 50 to 100 jobs for the one year it’s under construction.

Work on the facility should begin early next year and will take about a year to complete. The new laboratory should open at the end of 2011 or early in 2012.

13

NATIONAL INSTITUTES OF HEALTH CHALLENGE GRANTS

Through the American Recovery and Reinvestment Act the National Institutes of Health (NIH) formed a new initiative called the NIH Challenge Grants in Health and Science Research. Only several hundred awards were issued nationwide. According to the program, receiving these funds needed to pass “a rigorous evaluation of the impact of different options that are available for treating a given medical condition for a particular set of patients. Such a study may compare similar treatments, such as competing drugs, or it may analyze very different approaches, such as surgery and drug therapy.” With over 20,000 applications for the NIH Challenge Grant Program, Rutgers University was part of an exclusive group of research institutions to have multiple faculty members awarded these prestigious grants. The awardees were Dr. Linda Brzustowicz, Dr. Eileen White, Dr. Danielle McCarthy and Dr. Ron Hart.

14

Dr. Linda Brzustowicz : Searching For The Roots of Autism

Autism is a lifelong disorder that has no cure and affects an estimated 9 in 1,000 children in the U.S. and an even larger percentage in New Jersey, with an estimated 10.6 cases per 1,000 children.

Dr. Linda M. Brzustowicz was award-ed a $500,000 NIH Challenge Grant to research the genetic roots of the dis-

ease. The Rutgers genetics professor and her team are studying autistic people and their family members to try to find genetic biomarkers that can be used to identify specific language prob-lems in autistic people.

While there can be a tremendous range of severity in autism from mild to severe, autistic children often have great difficulty communicating and have problems with social interactions and behavior. Their parents and families face huge challenges as well. That’s why some 100 families of autistic children from New Jersey and neighboring states are participating in the study.

“It’s a devastating illness and I think families want to help,” says Brzustowicz. “Whatever they can do to prevent someone else from having that heartbreak they’re very interested in doing.”

Brzustowicz’s team is trying to correlate language difficulties in autistic people with common variations in genes. “The hypoth-esis is that what happened with people with autism is that they probably have multiple genetic problems that are causing the illness,” Brzustowicz explains.

The researchers look at the family history of people with autism and they include a wide circle of family members that includes aunts, uncles and grandparents. They give them a detailed bat-tery of tests that probes factors that could be linked to autism, such as obsessive-compulsive disorders or language problems. One part of the test, for example, shows whether people can understand and respond to ambiguity in language.

The researchers also get samples of the family members’ DNA, which gives them a detailed genetic profile of each individual.

That profile will show them where their subjects’ DNA varies from the DNA in the general population. The data will then be crosschecked against the behavioral data to see if the variations correlate with certain behavior.

Dr. Brzustowicz is a board-certified psychiatrist with training in molecular and statistical genetics whose Psychiatric Genet-ics Laboratory at Rutgers has researched a variety of serious behavioral disorders including autism and schizophrenia. Her research has often focused specifically on language problems.

The answers to the genetic roots of autism will likely not be simple, Brzustowicz warns. There could be 20 different genes or more that cause autism. But finding these biomarkers will not only lead to a better understanding of the root causes of autism, it could also one day lead to medications to treat the disease or even lead to a blood-based DNA test.

For the families, any answers about autism will be worth the ef-fort. “They really would like something more to be known about this illness,” Brzustowicz says. “Their hope is that maybe we’ll find something that will help their child in particular. They real-ly do recognize it may not be for their kids - it might be for kids in future generations that might benefit from this research.”

Dr. Eileen White: Probing How Cancer Cells Work

Death rates in the U.S. from cancer are on the decline, but more than half a million people died in the U.S. from cancer last year.

Dr. Eileen White, a Rutgers Professor of Molecular Biology and Biochemistry and the Associate Director for Basic Science at the Cancer Institute of New Jersey, won a $500,000 Challenge grant from the NIH for her work on the metabolism of cancer cells.

Dr. White is working with research partners at Princeton University to identify how the metabolism of cancer cells dif-fers from that of normal cells. Cancer cells divide rapidly and they have to produce energy both for cell division and produce building blocks for new cells, Dr. White explains. If scientists can pinpoint those metabolic differences, that could lead to new cancer therapies that would differentiate between the cancer

15

cells and normal cells.

“The cancer cells have a different metabolism,” she says. “If we poison their ability to make the building blocks for new cells, that would interrupt cell division and we would have a good drug.”

Dr. White and her research partners are analyzing the metabolic pathways of cancer cells and then trying to determine whether they can interfere with the genes that regulate those pathways. Identify-ing those genes may help lead to new drugs to fight cancer.

“This is a very exciting area of cancer research,” Dr. White says. “It’s probably one of the hottest areas in the field of cancer research.”

Dr. Ron Hart: A “Wild” Search for the Switches in Stem Cells

Dr. Ronald Hart uses words like “odd,” “wild,” “crazy,” and “far-fetched” to describe the research on stem cells that won him and his research partners at MIT a $1 million Challenge Grant from the National Cancer Institute.

The research concerns what signals the human epigenome–regulatory proteins that are bound to the DNA and control the function of the DNA beyond the regulation built into the DNA itself. Recent research suggests that enzymes modify the pro-teins to act as signals to switch cells on and off when cells begin differentiating at the beginning of life.

Hart and his partners’ idea is based on work by Dr. Hart’s former graduate student, Dr. Loyal Goff, who now works with Dr. Man-olis Kelli, of the Computer Science and Artificial Intelligence Laboratories and the Broad Institute at MIT, on the project.

They are researching whether “a newly described group of very small modules of RNA participate in this regulatory scheme and help decide where to mark the genome for switching on and off,” Hart explains.

“If they can understand the mechanisms that control how a stem cell shuts off genes as it becomes specialized, that will help researchers understand how some cells differentiate into cancer cells,” Hart says.

The research could also help contribute to regenerative medicine by allowing scientists to target specific areas of the body, he explains. “In some respects, this is going to be the most important grant

I’ve had in my career,” Hart says. “This is really the most inter-esting thing I’ve done in the entire time I’ve been here.”

Dr. Danielle McCarthy: If Smokers Won’t Quit, Rutgers Researcher Won’t Either – Smoking Cessation Lab Links Lifestyle to Treatment

It’s not over for prominent “Stop Smoking” or “Smoking Cessation” campaigns, not even close.

According to the Centers for Disease Control and Prevention’s recent report, after close to 40 years of continuous declines, the smoking rate among Americans has been stable since 2005 with roughly 25 percent of the population still addicted.

Dr. Danielle McCarthy, an assistant professor of Psychology at Rutgers-New Brunswick, is poised to test the efficacy of behav-ioral and pharmacological treatments that can interrupt learned habits.

Dr. McCarthy was awarded a Challenge grant for her proposal, “Phenotypic Markers for Smoking Cessation: Impulsive Choice and Impulsive Action,” which according to Dr. McCarthy will “study and test the ability of the Common-Sense Model of Self-Regulation to explain why smokers who have already experi-enced serious smoking-related health consequences continue to smoke, as well as studying impulsive decision-making and impulsive behavior as markers of difficulty quitting smoking.”

Cigarette smoking causes over 440,000 premature deaths annu-ally in the United States alone and costs the United States health system over $190 billion. Dr. McCarthy collaborates with Dr. Gretchen Chapman (Rutgers-New Brunswick Department of Psychology).

16

MAJOR INSTRUMENTATION AWARDSModern science requires state of the art instruments to be successful and produce new knowledge.

17

Ultra-High Resolution STEM Microscope; Rutgers Plans to Build World’s Most Advanced Electron Microscope

A project to build one of the most advanced electron microscopes in the world was singled out by the White House as an example of how federal stimulus funds are being used to fund innovative projects that are not only creating jobs but also bringing the econo-my into the future.

It was one of 100 projects men-tioned in a White House report on the American Recovery and Reinvestment Act. The report

said the research could lead to many new applications in indus-tries and create valuable high-tech jobs.

The $2 million in federal funds will make New Jersey home to a world-leading electron microscope that could lead to the devel-opment of new nano-materials in areas such as energy produc-tion and storage. For example, the new microscope could lead to more efficient batteries, ways to convert light to electricity, and chemical reactions that produce hydrogen.

A team of researchers led by Dr. Philip Batson, of the Depart-ment of Physics and Astronomy, a leading scientist in the field of microscopy, will work with the Nion Company in Kirkland, Washington, to create the ultra-high resolution scanning trans-mission electron microscope.

The device, which is expected to be finished by the end of 2012, will be a huge advance in the capabilities of electron micro-scopes, allowing scientists and engineers to view not only atoms but also vibrations of atoms.

The new microscope will also be used to help educate the public about science and will help prepare scientists and engineers in the emerging field of nanotechnology.

Sharing a Valued Resource

Dr. Nilgun Tumer received a Shared Instrumentation Grant from the NIH for a confocal microscope, which will be used as a shared resource for several research programs at the School of Environ-mental and Biological Sciences (SEBS) located on the Cook Cam-pus of Rutgers. The award was $419,000 and funded by ARRA.

It will be the nucleus of a multi-user Biological Imaging Facility on the Cook Campus. At least nine research labs spread across six de-partments will immediately benefit from access to such a facility.

The Biological Imaging Facility will provide investigators re-sources and training in modern cell biological imaging tech-niques and will enhance interdisciplinary activities among investigators. The major focus of the multi-user Biological Im-aging Facility will be the application of fluorescent probes as a means of investigating cellular processes relevant to protein and lipid transport with emphasis on the integration of highly sensi-tive and quantitative modern light microscopy techniques with molecular, biochemical and genomic approaches.

Imaging the Brain in Action

Rutgers University was recently awarded an NSF Major Re-search Instrumentation Award to create a research-dedicated neuroimaging center led by Dr. Stephen J. Hanson (Psychology) with Dr. Bart Krekelberg (Center for Molecular and Behavioral Neuroscience) and Dr. Mauricio Delgado (Psychology). The proposal involved 18 neuroimaging researchers from the New Brunswick and Newark Campuses.

The $1.8 million award will be used to acquire a Siemens TRIO 3T MRI scanner for a Brain Imaging Center that will be called Rutgers Brain Imaging Center (RUBIC). The center will sup-port diverse research in cognitive, perceptual and social neuro-science from all Rutgers campuses. The neuroimaging research embraces both basic and applied studies.

Neuroimaging has become a key technology in the brain and psychological sciences due to both the spatial and temporal resolution of functional Magnetic Resonance Imaging (fMRI) which can provide sub-second and sub-millimeter resolution of brain dynamics. These capabilities now allow precise mea-surement of local brain volumes and visualization of the source and destination of major neural pathways. Blood flow dynam-ics reflect changes in local neural activity, and its mapping has become a critical measure in exploring brain mechanisms of a variety of functions that underlay components of the learning sciences in terms of perceptual, cognitive, and social behavior.

18

Fighting Disease with Computational and Structural Biology

Dr. David Case from the BioMAPs group - Biology at the Inter-face with the Mathematical and Physical Sciences - received a NIH ARRA award of $433,000 for a computer cluster (80 spe-cialized computers) to utilize computational and structural bi-ology, structural genomics, and proteomics to study protein fold-ing. Abberant protein structures (misfolding) characterize such disease states characteristic of Parkinson’s and Alzheimer’s. The group of eight researchers using the computer cluster al-ready have NIH funding for specific projects which require this technology. A primary goal will be to improve methods for the characterization of protein structures and assemblies as a ba-sis for improving methods of structure-based drug design for treatments of AIDS and other diseases.

Looking Very Closely

An NSF Major Instrumentation Grant for $319,000 was awarded to Dr. Piotr Piotrowiak, from the Chemistry Department in New-ark, to acquire a Field Emission Scanning Electron Microscope.

This particular type of microscope permits microanalysis and imaging at the sub-micron to nanometer level. The research groups utilizing this microscope focus on the behavior of com-plex, inhomogeneous materials which have properties and functions linked to their micro and nanoscale structures.

New Technology and New Uses for Carbon 14

Dr. Daniel Murnick is in the Physics Department located in Newark. He was awarded an NSF grant for $740,000 to develop a Carbon 14 Analyzer. The use of Carbon 14 as an isotopic trac-er is widespread in many areas of science – it is a “natural” label of living systems used for carbon dating and tracing carbon in the atmosphere and biosphere systems. Labeling with 14C is important in biology and medical research and diagnostics and drug discovery.

Traditional methods to quantify 14C rely on the detection of a nuclear decay event, which is inefficient due to the need for high levels of radioactivity or very large samples and count-ing time. The new analyzer under development will use ultra-sensitive laser-based technology, called intracavity optogalvanic spectroscopy, eventually allowing the use of smaller samples for

new research and expediting existing research. Applications will range from pharmaceutical analyses to carbon dating and environmental monitoring.

19

RUTGERS DIVERSITY PROGRAMSRutgers University is consistently ranked as one of the top insti-tutions for diversity in higher education. According to U.S. News and World Report: America’s Best Colleges, Rutgers-Newark has been the #1 school for diversity for 14 consecutive years. Diversi-ty Inc. ranks Rutgers as one of the top 5 institutions for diversity management. Rutgers has many ongoing programs designed to attract, retain and educate students of all backgrounds.

STEM/Q-STEP: Two Camden Programs Aim to Make Today’s Students Tomorrow’s Scientists

“I’m committed to moving our country from the middle to the top of the pack in science and math education over the next decade… This is probably going to make more of a difference in determining how well we do as a country than just about anything else that we do here.”

- President Barack ObamaNovember 3, 2009

Today’s economy demands that young people have the skills in science, technology, engineering, and math (STEM) that will prepare them for an advanced, high-tech economy. But a report from the National Academies of Science noted in 2007 that U.S. students are falling behind students in other developed coun-tries in these areas and that women and minorities continue to be underrepresented.

That’s where programs like the Rutgers-Camden Q-STEP and the STEM Scholars program come in. Unlike colleges and uni-versities in most of the country, Rutgers-Camden has managed to attract more students majoring in these fields over the past few years and has more than doubled the number of women and minority students in the sciences over the past five years. But at the same time, the number of minority students graduat-ing in those fields has only increased by about 10 percent.

The Q-STEP (Quantitative-STEM Talent Expansion Program) has set itself an ambitious goal aimed at reversing that trend. Through a $307,000 grant from the National Science Founda-tion, Q-STEP hopes to increase the rate of STEM graduates at Rutgers-Camden by 25 percent.

The STEM program is aimed at helping students graduate in the science, technology, math and engineering fields by giving them financial help, mentoring and extra help with their college courses and career preparation. It offers need-based scholar-ships to students with a STEM major through a $600,000 Na-tional Science Foundation Scholarships in Science, Technology, Engineering and Mathematics (S-STEM) program.

Starting in the fall of 2010, up to eight incoming freshman re-ceived tenure scholarships of $3,000 per year for four years, while another five current students received scholarships of $3,000 for one year. They also can participate in the mentoring and workshops offered by the Q-STEP program.

“The overall purpose of this grant is to take this increase in sci-ence majors and help them go through and actually graduate,” explains Dr. Joseph Martin, a Professor of Biology who directs the Q-STEP program. “The NSF perspective is that we’ll bring a larger and different group of talent into the science area.”

The 20 Q-STEP scholars enrolled in the program since its start in 2009 were chosen from a group of students interested in the sciences who reflect the Camden student population. The stu-dents attend weekly workshops to help them with their course work and meet with student mentors who are upperclassmen in STEM subjects. The Q-STEP students also had the opportunity to take part in research projects at Camden, and students assisted with re-search on circadian rhythms and the developmental patterns of the fruit fly over the summer.

Q-STEP is working to create a community of students in the sciences where students can learn and interact with each other.

20

The program is renovating a building on Cooper Street where students can meet each other, talk to mentors and attend work-shops and meetings.

The five-year program will eventually serve a total of 90 stu-dents with 30 paid mentors.

The Rutgers Future Scholars Program Helps Area Students Succeed in College

There is widespread agreement that today’s students must have strong backgrounds in mathematics in order to be prepared to be leaders in science, technology and mathematics. That makes the nationwide and statewide achievement gap between black and white students all the more alarming. Black students scored 31 points behind white students in mathematics nationwide in 2007, while black students in New Jersey were 25 points behind white students.

Rutgers has a strong commitment to narrowing that gap, and the Rutgers Future Scholars Program is evidence of that mis-sion. It’s one of the most ambitious pre-college programs in the country and it’s one of the few that begins working with young people as early as middle school and then provides successful students with full scholarships.

Studies show that people with a college education earn higher salaries, are more healthy, are more economically independent and less likely to be involved with the criminal justice system and they’re much more likely to be skilled workers who pay their taxes. Taking all these factors into account, the program estimates that the total fiscal gain for each scholar averages out to $150,000.

The Future Scholars Program begins working with a select group of promising low-income students when they’re enter-ing the eighth grade and keeps providing academic help, en-couragement and inspiration with the goal of giving qualified students a full-tuition scholarship to attend Rutgers.

The program began in 2008 and each year selects 50 students each from Rutgers’ home communities of Camden, Newark, New Brunswick and Piscataway whose parents did not attend college. The students receive tutoring mentorship during the school year, and they learn about everything from forensics to poetry, take trips and spend a week on the college campus each summer. This year, The Center for Structured Organic Particu-

late Systems (C-SOPS) participated in the program and intro-duced students to the pharma field.

Louis Stokes Alliance for Minority Participation: Rutgers Joins Statewide Program Aimed to Increase the Number of Minority Students in the STEM Fields

It’s not enough to recruit minority students into the science, math, engineering and technology fields. Many minority stu-dents also need financial and academic help in order to gradu-ate in those fields.

Rutgers is part of a statewide program called the Garden State Louis Stokes Alliance for Minority Participation(LSAMP) that joins nine New Jersey colleges and universities with a nation-wide program.

“Everybody gets so gung ho about doing this,” says Professor Alexander Gates, the Executive Director of the program. “They just think it’s a fantastic opportunity. They think it’s great. Even that improvement in self-confidence – that you’re going to be successful. I think that helps a lot.”

Established in 1989 with a $5 million grant from the National Science Foundation, the program has an ambitious goal: dou-bling the number of minority students graduating in the STEM fields. That would mean increasing the number of minorities who graduate in the STEM fields at the nine schools in the alli-ance to 1,000 by the year 2014.

The LSAMP program just kicked off last fall. The program strives to create a learning community designed to make ev-eryone successful. That means providing academic support through tutoring and peer-led team learning that includes workshops on subjects like how to take notes or how to apply and interview for jobs. It pays some of the LSAMP scholars who are high-achieving students in the science fields a stipend to work with the other students. They also get the opportunity to do research with faculty members. Those students who go on to graduate programs may qualify for a full scholarship to take graduate courses abroad.

The “hidden agenda,” Gates says, is not just to get students to graduate from college with a STEM degree but to encourage those students to go on to graduate school in those fields. “The underlying agenda is to get them to pursue science, technology, engineering, math at a higher level,” he says.

If the LSAMP program is successful in meeting its goals, it will be eligible for another $5 million NSF grant. More importantly, it will help hundreds of minority students at Rutgers and at uni-versities across the state to graduate in the sciences.

21

K-12 PROGRAMSRutgers University has always maintained a commitment to education, not only undergraduate and graduate students but also to future Scarlet Knights in the K–12 pipeline. The eco-nomic future of our state and our nation depend on our having young people who have the skills and knowledge to contribute to an increasingly complex and technological world.

Rutgers has a myriad of programs that reach out to youngsters from kindergarten through twelfth grade throughout the state of New Jersey aimed at preparing our leaders of the future. The University is strongly committed to fulfilling its commitment to helping disadvantaged young people in the state to go to college.

Science Preparation Alliance of Rutgers & Camden: Trying to Ignite Students’ Interest in the 3-B Sciences

One pre-college program at Camden is SPARC, the Science Preparation Alliance of Rutgers & Camden. SPARC is an al-liance of educational, scientific and service organizations that is focused on sparking students’ interest in the sciences, par-ticularly the “3-B” sciences: the biological, brain, behavioral and cognitive sciences.

Engineering Research Center on Structured Organic Particulate Systems: Reaching Out to Tomorrow’s Engineers

Major research centers on the Rutgers Campus are also reach-ing out to K-12 students. The Engineering Research Center on Structured Organic Particulate Systems (ERC-SOPS) is part of a program with several other universities with the theme “Build-ing Foundations: From A.B.C. to P.H.D. to J.O.B.” It includes the “Engineering the Future Outreach Program” that offers en-gineering education programs for students, parents and teach-ers. Its Education and Training Institute trains undergraduates, graduates, postdocs and professionals in pharmaceutical re-search and manufacturing and holds educational programs for industry professionals.

Institute of Marine and Coastal Sciences: Students Find IMCS’s COOL Classroom Really is Cool

The IMCS also has K-12 programs as one of its core missions and developed a curriculum in conjunction with the Jacques Cousteau National Estuarine Research Reserve and several oth-er partners with support from the National Ocean Partnership Program. The result is the Coastal Ocean Observation Labora-tory’s C.O.O.L. Classroom website that links middle school and high school teachers and students to lesson plans and activi-ties with active research taking place at IMCS off New Jersey’s coastline.

Center for Advanced Infrastructure and Transportation: Future Engineers Learn About Transportation Careers

The CAIT program is working with youngsters through a part-nership with the Garrett Morgan Academy, a charter school in Paterson, N.J. CAIT takes part in a pre-college program for future engineers that just graduated its first class. It also col-laborated with the Morgan Academy on the New Jersey Sum-mer Transportation Institute, a four-week program to train 25 incoming high school students about careers in transportation.

CAIT takes part in a nationwide celebration of engineering for K-12 students called Engineers Week, or E-Week, that culmi-nates with Future City, a full-day competition for middle-school students in which students design the city of the future.

Center for Discrete Mathematics and Theoretical Computer Science: Reaching Out to Young Mathematicians

DIMACS has a program that focuses on high school students who are gifted in mathematics. Each summer, 30 students come to Rutgers for the Young Scholars Program in Discrete Math-ematics where they learn about the many applications of math-ematics to research, do problem-solving of their own and get to meet professionals who serve as role models and mentors. They go on field trips, do research activities and get to take part in technology activities like robot building.

Rutgers Science Explorer: A Rolling Science Laboratory Travels N.J.

Hundreds of children in New Jersey have gotten to know the Rutgers Science Explorer over the years. It’s a 40-foot, state-of-the-art mobile classroom and laboratory that brings hands-on science activities to middle schools and junior high schools all over the state. The Rutgers Science Explorer is staffed by Rut-gers graduate and undergraduate students who received special teaching fellowships funded by the National Science Founda-tion. Students can learn about forensics, find out all about pe-troleum and oil, learn about marine ecology or matter or mi-crobes that cause disease.

22

BRIEFS ON RUTGERS RESEARCH PROGRAMSPresidential Early Career Awards for Scientists and Engineers: Rutgers Tops the List

Rutgers was the only institution in the country to have three faculty members win a prestigious Presidential Early Career Award for Scientists and Engineers (PECASE) at a White House ceremony hosted by President Barack Obama in January.

The three winners were Dr. Jimmy de la Torre of the Depart-ment of Educational Psychology, Dr. Charles R. Keeton II of the Department of Physics and Astronomy, and Dr. Hao Lin of the Department of Aerospace Engineering.

Dr. De la Torre won the award for his research into how diagnostic assessments can be used to improve classroom teaching. Dr. Lin was awarded for his innovative research applying principles of fluid me-chanics to biological sciences by exploring how electrical fields could be used to open cell walls to deliver medicines or genes.

Dr. Keeton received the award for his work on “gravitational lensing”, in which distant galaxies bend light with their gravity and for his research on new theories and methods to describe dark matter.

The three young researchers previously received five-year NSF Early Faculty Career Development (CAREER) awards given to outstanding young faculty members to pursue their research and share their knowledge through outreach programs.

Magnetic Resonance Imaging as a Tool to Pinpoint Prostate Cancer

Rutgers University researchers received a $3.4 million federal grant to develop tools that will help pinpoint prostate cancer us-ing MRIs, or magnetic resonance imaging, under the leadership of Dr. Anant Madabhushi.

The five-year grant from the National Institutes of Health is funded in the first two years with stimulus funds from the American Recovery and Reinvestment Act of 2009.

The research could help the diagnosis and treatment of prostate cancer, which kills 27,000 men each year. Some 190,000 new

23

cases are diagnosed annually.

Rutgers is working with researchers from the Hospital of the University of Pennsylvania and with Siemens USA on studies that show how MRIs can be used to determine the exact loca-tion of cancerous tissue in prostate glands. It could eventually provide a non-invasive method of diagnosing cancer. With im-proved diagnostic methods, surgery could be avoided in some patients with low-risk cancers.

American Council of Learned Societies New Faculty Fellows: Seven Fellowship Winners Choose Rutgers

Fifty promising young scholars received the New Faculty Fel-lowships from the American Council of Learned Societies. This year, seven selected Rutgers as their fellowship site.

Rutgers is proud of the fact that it attracted so many of these promising young fellows – more than any other university par-ticipating in the program.

The New Faculty Fellowships are a kind of “stimulus” for schol-ars in the humanities and social sciences who work hard for their Ph.D.s only to face what the ACLS calls a “jobless market.”

Funded by the Andrew W. Mellon Foundation, the program pays a $50,000 stipend, plus a $5,000 allowance for travel and research and moving expenses, to new fellows at participating universities and colleges where they will have a good chance of being offered a permanent position.

Dean of Humanities James Swenson attributes Rutgers’ success to its taking an “aggressive stance” to attract the scholars. Led by Vice Dean Robin Davis, the university gave “carte blanche” to departments to make offers to fellows in the program, Dean Swenson says. And it comes at a time when Rutgers has its own tight budget to worry about. As Dean Swenson puts it, “In this era of budgetary constraints and uncertainty, this program has allowed Rutgers to recruit some of the finest and most innova-tive young scholars in the humanities.”

The ACLS New Faculty Fellows at Rutgers are: Jefferson Decker, Columbia University and Andrew T. Urban, University of Min-nesota, American Studies; C. Michael Sampson, University of Michigan, Ann Arbor, Classics; Jamie L. Pietruska, MIT, Histo-ry; Matthew Walker, Yale, Philosophy; Karen Bishop, University of Chicago, Spanish and Portuguese; Kyla C. Schuller, Univer-sity of California San Diego, Women’s and Gender Studies.

National Institutes of Health Director’s Awards: Grant Awards Innovative Research Using Nanotechnology

The NIH awarded one of its prestigious Director’s New Innova-tor Awards to KiBum Lee, an Assistant Professor in the Depart-ment of Chemistry and Chemical Biology.

The $2.3 million five-year grant is intended to promote highly innovative research that has the potential of being very benefi-cial to society and to support exceptionally creative new inves-tigators.

Lee leads a research group that is working on developing and using nanotechnologies and chemicals to alter the signaling pathways of cells such as cancer or stem cells to induce the cell to behave in a certain way. They are focusing specifically on how microenvironmental cues affect stem cells.

By using nanotechnology to manipulate human stem cells, the researchers hope to ultimately develop therapies for neurode-generative diseases.

National Institutes of Health MERIT Awards: Rutgers Research in Obesity is Recognized

Method to Extend Research in Time (MERIT) awards support investigators whose research competence and productivity are distinctly superior and who are highly likely to continue to per-form in an outstanding manner. Investigators may not apply for a NIH MERIT award. Scientists within the NIH identify can-didates for the MERIT award during the course of reviewing competing research grant applications.

Rutgers has the distinction of having three active MERIT-fund-ed faculty: Dr. Eddie Arnold, who studies how HIV-1 resists the drug AZT; Dr. Patrick J. Sinko, (who also won the Rutgers Board of Trustees Award for Excellence in Research) who con-ducts research on the use of nanotechnology for drug delivery to treat HIV; and Dr. George M. Carman, who has been study-ing the underlying cell processes that cause obesity.

“Obesity is such an epidemic in the whole world,” says Dr. Car-man. “People are more concerned with obesity than they are with cancer.”

More than 30 percent of adults and 17 percent of children in the U.S. are obese, and this national epidemic has an economic cost. The Organization for Economic Cooperation and Devel-opment issued a report this fall warning that the U.S. already pays 1 percent of its gross domestic product in healthcare costs and lost production due to obesity and that amount could triple over the next decade.

Dr. Carman is a food science professor and Director of the Rut-

24

gers Center for Lipid Research whose laboratory has received NIH grants for 28 years – one of the longest running grants at Rutgers.

The laboratory discovered the gene for the enzyme the body uses to make fat and has since been trying to pinpoint how the enzyme works and what switches the enzyme on and off.

“Our ultimate goal is to find inhibitors of the enzyme to combat obesity,” Carman explains. “An inhibitor might combat obesity and an activator might produce more fat for people who need it.”

25

INDUSTRY – UNIVERSITY INTERFACEThroughout the region, Rutgers plays an important part in the design, discovery and the development of ideas and innovation. Rutgers also utilizes its vast network of partner companies to commercialize many of the technologies, techniques and know-how that Rutgers faculty possess. Through a variety of programs Rutgers continues to be a resource for companies that want to hire students and graduates or commercialize University tech-nologies.

Professional Science Master’s Program: A New Program in Business and Science Offers a Path for Science Graduates

A 2008 report by the National Research Council recommended four-year research universities like Rutgers invest in Profession-al Science Master’s (PSM) programs as a way of making U.S. industries more competitive globally. Advocates say the degrees offer a strong academic background to the 80 percent of science and technology students who are entering the workforce and are not interested in getting a Ph.D. or pursuing an academic career. Rutgers is taking the lead in that effort with a new PSM program that gives students a strong background in science and technol-ogy and top-notch business skills. The university’s PSM program received a $700,000 grant from the National Science Foundation to support recruitment and fel-lowships for students. The National Science Foundation selected

Rutgers and just 21 schools nationwide out of a pool of 210 appli-cants to receive $14.5 million in funding for PSM programs from the American Recovery and Reinvestment Act of 2009. The master’s of business and science degree offers students graduate level courses in the sciences and business and policy at all three of its campuses. Students can choose from more than a dozen concentrations that include drug discovery and develop-ment, biotechnology, genomics and sustainability. Rutgers’ Master’s of Business and Science (MBS) program has also begun a collaboration with Pohang University in South Korea that will allow the two universities to share resources through exchange programs and visiting scholars, and more partnerships are planned in the future. The university also began a BS/MBS program this year that al-lows highly qualified Rutgers juniors to begin MBS graduate courses in their senior year.

National Science Foundation Industry/University Cooperative Research Centers: Rutgers Promotes Partnerships

The NSF Industry and University Cooperative Research Pro-gram (I/UCRC) provides opportunities to research universities to partner with other leading institutions to conduct industri-ally relevant research, receive seed funding and recognition as a National Science Foundation (NSF) research center and access to professional resources and guidance aimed towards enhanc-ing global competitiveness.

Each center is established to conduct research that is of inter-

26

est to both the industry and the university with which it is in-volved, with the provision that the industry must provide major support to the center at all times. The centers rely primarily on the involvement of graduate students in their research projects, thus developing students who are knowledgeable in industrially relevant research.

The mission of the Ceramic and Composite Materials Center (CCMC), led by Professor Richard Haber, is to develop new interdisciplinary technologies to make the United States more competitive in ceramic science and engineering and to trans-fer these technologies to its industrial members in order to foster the development of competitive, reproducible ceramic and polymer/ceramic composite materials for advanced, high-performance systems. Rutgers University serves as the lead in-stitution in collaboration with University of New Mexico and Pennsylvania State University.

The Center for the Integration of Composites into Infrastruc-ture is a National Science Foundation (NSF) Industry/Universi-ty Cooperative Research Center which began operations in July 2009. The primary objective of the center is to usher applica-tions of composites in civil and military infrastructures to the next level through collaborative efforts among West Virginia University, Rutgers, the State University of New Jersey, North Carolina State University and the University of Miami, Florida. The goal is to synergize different fibers and polymers to create new application areas expanding market potential. At Rutgers the efforts are led by Professor Perumalsamy Balaguru.

The Center for Autonomic Computing (CAC), led in New Jersey by Rutgers Co-Director Manish Parashar, covers a broad area of scientific and engineering research on methods, architectures and technologies for the design, implementation, integration and evaluation of special- and general-purpose computing sys-tems that are capable of autonomously achieving desired be-

haviors. CAC research activities involve several disciplines that impact the specification, design, engineering and integration of autonomic computing and information processing systems. In collaboration with the founding companies, including BAE Systems, Citrix EWA Government Systems, IBM, Intel, Imagin-estics, ISCA Technologies, Merrill-Lynch, Microsoft, Motorola, Northrop-Grumman, NEC, Raytheon and Xerox, the research is conducted at University of Florida, Mississippi State Univer-sity, University of Arizona and Rutgers University.

With support from NSF, Dr. Dimitri Metaxas is planning an NSF I/UCRC entitled Center for Dynamic Data Analytics – CDDA. The purpose of this center will be to advance knowledge about how to analyze and visualize massive, complex, multidimensional and multiscale dynamic data.

There are two universities which are the founding members of CDDA: Rutgers University and Stony Brook University. The Center intends to conduct innovative research and develop ap-plications based on the collaborative efforts between the two Universities and the member companies (Adobe, IBM, Intellec-tual Ventures, Lawrence Livermore Laboratory, Siemens) in the emerging field of dynamic data analytics. The end result will be novel science, algorithms and applications that transform chaos (due to the size of the data) into knowledge.

Many of today’s and future scientific applications are confronted with the need for analysis and/or visualization of complex data. Such data pose new challenges in algorithm design for analysis and visualization that traditionally have not been addressed.

The Rutgers center intends to close a necessary loop between science and applications that is often not present in computer science research and education. The algorithm design will be tested, validated and improved based on the close collaboration and research between the two participating universities and in-dustry. This loop of algorithm design, testing and improvement can only be done by a University-Industry collaboration and is absolutely necessary due to the complexity of the data and the present absence of relevant algorithms.

The center will not only advance the science of dynamic data analytics but will also accelerate its transfer to industry by closely working with industrial partners in the definition and prioritization of projects to be pursued by the CDDA. It will also seek to involve students and faculty from underrepresented groups through several dissemination and recruiting initiatives. Students will also spend time at industrial affiliates during the academic year or in the form of summer internships.

27

FUNDING TO SUPPORT RUTGERS GRADUATE EDUCATIONRutgers graduate programs continue to be recognized for both their achievements in education and also for their dedication to the exploration of innovative thinking and research practices.

Each of the competitive programs that follow are awarded to a faculty member in a Rutgers graduate program which identify the graduate students who will benefit the most from the par-ticular research experience available.

Graduate Assistance in Areas of National Need

Rutgers has eight active GAANN (Graduate Assistance in Areas of National Need) awards of $450,000 to $650,000 each from the U.S. Department of Education that are used to provide fel-lowships to numerous graduate students in science, engineering and mathematics. The current grants were awarded to:

Mathematics (PI: Michael Saks), Chemistry & Chemical Biol-ogy (PI: Martha Cotter), Physics (PI: Ronald Dean Ransome), Pharmaceutical Engineering (PI: Yee Chiew), Environmental Science (PI: Daniel Gimenez), Biomedical Engineering, (PI: Martin Yarmush), Education (PI: Jimmy de la Torre), and Bi-ology at the Interface with the Mathematical and Physical Sci-ences (PI: Ron Levy).

Integrative Graduate Education and Research Training

Rutgers holds six IGERT grants (Integrative Graduate Educa-tion and Research Training) from the National Science Founda-tion - among the most of any school in the nation – for science and engineering graduate students pursuing research that cuts across academic disciplines and could potentially have a broad social impact.

The two newest IGERTs, totaling more than $6.4 million, are focused on graduate research on clean and sustainable energy.

• A project to develop a training program in sustainable and clean energy technologies with an emphasis on innovations in nanotechnology, and to conduct an exchange program be-tween the U.S. and Africa, led by Dr. Manish Chhowalla en-titled Nanotechnology for Clean Energy.

• A project to develop a training program in renewable and sustainable fuel solutions and collaborate with universities in the U.S., Brazil, China and South Africa led by Dr. Eric Lam entitled Solutions for Renewable and Sustainable Fuels.

The additional IGERTs follow:

• A graduate training program at Rutgers in perceptual science trains students in various disciplines to use the formal tools of computer models, as well as theoretical and experimental tools to study human perception led by Dr. Eileen Kowler, entitled Interdisplinary Training in Perceptual Science.

• Dr. Prabhas Moghe directs two IGERTS: Integrated Science and Engineering of Stem Cells, and a second, Integratively Engineered Biointerfaces. Together the research will integrate stem cell biology with research in biomaterials, process engi-neering and computational modeling.

• Dr. Fernando Muzzio leads the IGERT: NanoPharmaceuti-cal Engineering and Science program focusing on the appli-cation of nanotechnology for the design and optimization of pharmaceutical products.

Mellon Foundation Grant: Graduate Support for the Humanities

Rutgers is the recipient of a three-year grant in the amount of nearly $3 million to support graduate humanities programs in the School of Arts and Sciences (SAS). The grant targets six SAS humanities programs to help them recruit the most qualified students and provide support towards their doctorates.

Rutgers supports more than 100 students in Art History, Com-28

parative Literature, English, History, Linguistics, and Philosophy with the Mellon award. The three pillars of the grant include 1) stipend enhancements designed to help recruit and support the students best prepared to work with faculty in English, History, and Philosophy, 2) summer research/writing grants designed to support students who are making excellent progress on course-work and dissertation research, and 3) competitive dissertation fellowships administered by SAS.

Institutional National Research Service Awards

The Institutional National Research Service Award is a five-year grant from the National Institutes of Health that allows insti-tutions to award support to individuals to do predoctoral and postdoctoral research training in specified shortage areas.

This year Rutgers received nine such grants for research training in areas that range from studies of criminal justice and mental illness to research in biomaterials and pharmacology. ENDING ON A MUSICAL NOTE: CONRAD HERWIG

Dr. Conrad Herwig is balancing dozens of activities as a performer, composer and Rutgers professor, but to Herwig, all those strands of his life fit together.

“The great thing about teaching at Rut-gers is it’s sort of like your job is your hobby or your hobby is your job,” he ex-plains. “Our craft of music and jazz is what you teach. The process is a holistic process.”

Herwig and his band just performed at the Newport Jazz Fes-tival last summer, and he’s just released his 20th CD as a leader and performed at Carnegie Hall with the Mingus Big Band in September.

He was born in Oklahoma and grew up in Hawaii where he at-tended the Punahou School at the same time as President Ba-rack Obama. He is a member of the Oklahoma Jazz Hall of Fame where he is performing a concert this fall. He is also a visiting professor at New York’s prestigious Julliard School of Music.

He has performed in dozens of bands for singers that included Frank Sinatra and Tito Puente.

Herwig has often served as musical director and arranger for The Mingus Big Band, named for the late renowned jazz per-former and composer Charlie Mingus. He performed with them at Carnegie Hall and was Artist in Residence with the band at the University of Vermont.

The jazz trombonist sees all those strands as part of improvising that is part of life and part of his goal as an educator. “What you see is that life is really jazz and jazz is life. In a sense we’re all im-provising daily,” he explains. “What we’re trying to do at Rutgers is create innovative, improvisational thinking. My belief is that jazz has formed that process.”

Herwig is a prolific composer and performer. He and his band, the Latin-Side All Star Band, have been nominated for a Gram-my three times, most recently in 2009 for “The Latin Side of Wayne Shorter” featuring Eddie Palmieri. The group’s latest CD is “The Latin Side of Herbie Hancock” featuring Afro-Caribbe-an arrangements by Herwig. The music had the audience up on its feet dancing at the Newport Jazz Festival. The band has also performed recently at the Monterey Jazz Festival, the Heineken Puerto Rico Jazz Festival and they will appear at the Panama Jazz Festival in January.

He has also given an Afro-Caribbean beat to the music of jazz greats like John Coltrane and Miles Davis. “When you create a fusion between the two styles, it kind of gives it a new life,” Herwig explains. “You’re creating a new hybrid, so to speak, that excites people because rhythmically Afro-Caribbean music is very exciting. It gives these compositions that are familiar a different flavor.”

The musician says pursuing all these activities and teaching at Rutgers is a matter of time management. He uses a composing software called Sibelius Music Notation software that allows him to work on airplanes and in hotel rooms and wherever he goes.

Herwig holds a National Endowment for the Humanities grant for performing and recording. He has received a Rutgers Board of Trustees Research Fellowship for Scholarly Excellence award and is an associate professor of Jazz Studies at Rutgers. He used part of the funds from the fellowship to create the Rutgers Jazz Library, an ongoing project that is archiving and preserving Rutgers’ jazz scores and storing the pieces digitally. He is also the founder of the Rutgers Summer Jazz Institute.

And as if those activities weren’t enough, Herwig is also working on his own original compositions. The Rutgers Symphony per-formed the composer’s suite of original Afro-Caribbean music “Reflections of a Man Facing South,” commissioned by Princ-eton University at Symphony Space, and it will be performed again at Lawrence University in Wisconsin.

Herwig compares being a jazz musician to being a painter. “You’re painting in sound and the audience is the canvas for a jazz musician,” he says. “Going out and doing these performanc-es is really the way that a jazz musician practices his craft.”

29

Photo Credit: Daniel Miller

Research Leadership at Rutgers

Michael J. Pazzani, Ph.D. Vice President for Research and Graduate and Professional Education

Patrick Sinko, Ph.D. Associate Vice President for Research

Richard Mammone, Ph.D. Associate Vice President for Corporate Liaison

Office of Research and Sponsored Programs

New Brunswick:Sheryl N. Goldberg

Director, Office of Research and Sponsored Programs Editor, Research and Innovation at Rutgers 2010

Newark Campus:Jacqueline Cornelius

Director Sponsored Programs

Camden Campus:Carberta Morrison

Director of Sponsored Research

Photography: John Emerson, Don Hamerman, Nick Romanenko, Daniel Miller

30

Office of Research and Sponsored Programs New Brunswick

Sheryl N. GoldbergDirector

D. Dee EvansAssistant Director for Grants and Contracts

Grant Specialists:Casandra BurrowsFana CampbellMichele CoralLori DeMartinoSarah DumaisMonika InczeNicole NicholasMichael Toleno

Michelle GibelIRB Administrator

Lauren ZizzaCompliance Administrator

Lena FullemBusiness Analyst

Diane FrenchProgram Coordinator

Thao WillamsAdministrative Assistant

Cathy RiveraAdministrative Assistant

31

APPENDIX - I RUTGERS SPONSORED RESEARCH HIGHLIGHTS

The following graphs and tables break down Rutgers

extramural funding for FY2010. Rutgers received $433.9M

in sponsored research funding, 10.7% more than the prior

year. The federal government provided $329.9M in funds up

$61.5M from the prior year. Corporate funding for research

was up slightly to $18.8M from $17.0M. 805 Rutgers faculty

members received a total of 2011 grants and contracts, up

from 772 faculty receiving 1921 awards the prior year.

32

33

34

35

36

Commission on Science and Technolog $2 6 $3 1

Total Rutgers Awards Over Five Years by Funding Source(In Millions of Dollars)

Funding Source Sponsor 2006 2007 2008 2009 2010

FederalDepartment of Commerce $5.4 $3.6 $6.0 $4.5 $10.0National Aeronautics and Space Administration $2.8 $1.2 $2.8 $1.8 $2.8National Institutes of Health $70.3 $101.7 $65.5 $83.2 $131.7National Science Foundation $48.4 $43.2 $48.3 $58.6 $75.4Department of Agriculture $9.6 $6.5 $13.1 $22.7 $30.3Department of Defense $12.2 $16.1 $22.5 $55.8 $20.0Department of Education $4.0 $5.2 $6.3 $7.3 $8.3Department Of Energy $4.7 $4.9 $9.3 $5.2 $10.3Department of Labor $0.0 $0.3 $2.6 $2.3 $2.3Department of Transportation $6.7 $4.4 $23.7 $12.5 $18.6Environmental Protection Agency $2.3 $1.4 $1.8 $.6 $3.9Other Federal $5.3 $7.9 $9.4 $13.8 $16.1Total $171.6 $196.3 $211.2 $268.4 $329.5

Associations/FoundationsNonprofit Associations & Foundations $44.4 $47.0 $45.1 $62.1 $39.9Other State, Local & Foreign Governments $0.6 $0.8 $0.9 $1.5 $2.0Total $45.0 $47.8 $46.0 $63.6 $41.9

State of New JerseyCommission on Cancer Research $1.5 $2.4 $2.8 $2.3 $1.9Commission on Science and Technology y $2 6. $ 8$.8 $3 1. $ 9$.9 $ 3$.3Department of Children and Families* * * * $3.9 $6.3Department of Community Affairs $1.8 $2.2 $2.7 $2.9 $1.8Department of Education $4.5 $3.8 $5.3 $4.2 $3.0Department of Environmental Protection $2.4 $2.5 $2.7 $2.6 $1.8Department of Health and Senior Services $3.4 $2.8 $1.5 $4.4 $2.3Department of Human Services $22.5 $8.7 $11.8 $7.1 $10.8Department of Labor $1.6 $1.7 $1.2 $2.9 $3.2Department of Law and Public Safety $1.7 $1.1 $1.0 $.9 $2.2Department of State $1.5 $1.4 $1.3 $.8 $.7Department of the Treasury $4.4 $1.5 $3.7 $.0 $.3Department of Transportation $4.8 $3.9 $6.3 $4.1 $3.6County, Local, & Other NJ Agencies $7.3 $8.0 $10.4 $5.7 $5.5Total $60.1 $40.7 $53.9 $42.8 $43.7

* Agency Newly Formed in 2008

CorporationsCorporate Contracts $17.3 $22.8 $14.7 $15.5 $17.7Corporate Grants-in-Aid $3.7 $2.0 $1.4 $1.5 $1.1Total $21.0 $24.8 $16.1 $17.0 $18.8

GRAND TOTAL $297.8 $309.7 $327.2 $391.9 $433.9

37

20. AMATUCCI, GLENN G Ceramics / Ctr Ceramics Rsch 7 $2,425,000.00

Largest Total Dollar Awards by PI: Top Thirty

PI Name Related Unit(s)# of Awd Total

1. TISCHFIELD, JAY A Genetics / Human Genetics Institute 17 $54,635,549.09

2. EDWARDS, RICHARD Institute for Families / School of Social Work 4 $13,924,173.00

3. MONTELIONE, GAETANO T Ctr Advanced Biotechnology & Medicine 7 $13,241,982.00

4. MAHER, ALI Ctr Adv Infrastructure & Transportation / Civil & Environ Engineering 6 $11,126,700.00

5. BERMAN, HELEN M Chemistry & Chemical Biology 4 $9,191,010.00

6. BARON, JERRY J Office of IR-4 8 $8,217,026.72

7. PALMER, DEBRA Administration & Central Services 3 $7,485,263.00

8. BARONE, JOSEPH Pharmacy - Dean's Office / Pharmacy Practice & Administration 24 $6,109,420.00

9. MUZZIO, FERNANDO J Engineering Research Center / Bureau of Engineering Rsch 8 $5,627,723.00

10. ROBERTS, FRED S DIMACS 13 $5,588,254.00

11. LARROUSSE, PAUL J Bloustein - National Transit Institute 5 $5,107,437.00

12. GLENN, SCOTT M Institute of Marine & Coastal Sciences 6 $4,945,755.00

13. KOHN, JOACHIM Chemistry & Chemical Biology 12 $4,705,318.89

14. HOPPER, BRENDA B Grad School of Management - Small Business Development Center 11 $4,299,995.61

15. GARFUNKEL, ERIC L Inst Adv Materials, Devices & Nanotech / Chemistry & Chemical Biology 5 $2,750,443.00

16. LEE, KI BUM Chemistry / Chemistry & Chemical Biology 2 $2,688,043.00

17. LIPMAN, EDWARD V JR Office Continuing Professional Education 12 $2,627,600.00

18. IERAPETRITOU, MARIANTHI Chemical & Biochem Engineering / Engineering Rsch Ctr 8 $2,426,062.00

19. BRUZIOS, CHRISTOPHER Bloustein - Center for Survey Research 15 $2,426,048.00

20. AMATUCCI, GLENN G Ceramics / Ctr Ceramics Rsch 7 $2,425,000.00

21. MILLER, JANE E Institute for Health 1 $2,370,658.00

22. PLINIO, ALEX J Rutgers Business School - Organization Management 6 $2,322,500.00

23. BONILLA, GLORIA Public Policy & Admin / Ctr Strategic Urban Community Leadership 14 $2,294,945.23

24. OBROPTA, CHRISTOPHER C Environmental Science 10 $2,211,953.00

25. COHEN-CORWIN, AMY Ctr Math Science & Computer Education 2 $2,194,669.00

26. GUCUNSKI, NENAD Ctr Adv Infrastructure & Transportation 2 $2,141,966.00

27. LASKIN, DEBRA L Pharmacy - Pharmacology & Toxicology 7 $2,092,442.00

28. DE LUCA, MICHAEL P Institute of Marine & Coastal Sciences 8 $2,049,940.00

29. BATSON, PHILIP E Inst for Adv Materials, Devices & Nanotech 1 $1,972,867.00

30. RAYCHAUDHURI, DIPANKAR Electrical &Computer Engineering / Wireless Information Network Lab 7 $1,967,000.00

Total for Top 30 Investigators 235 $191,167,743.54

FY2010 GRAND TOTAL 2013 $433,878,925.54

38

CORPORATIONS

Largest Projects by Sponsor Category: Top Five

PI/Related Unit Sponsor Award

FEDERAL

1. TISCHFIELD, JAY A National Institutes of Health $20,124,323.00Human Genetics Institute

2. MONTELIONE, GAETANO T National Institutes of Health $12,592,442.00Ctr Adv Biotechnology & Medicine

3. TISCHFIELD, JAY A National Institutes of Health $9,492,078.00Human Genetics Institute

4. PALMER, DEBRA US Department of Agriculture $7,116,243.00Administration & Central Services

5. BERMAN, HELEN M National Science Foundation $6,382,943.00Chemistry & Chemical Biology

STATE OF NEW JERSEY

1. EDWARDS, RICHARD New Jersey Department of Human Services $8,556,601.00Institute for Families

2. EDWARDS, RICHARD New Jersey Department of Children & Families $3,500,000.00School of Social Work

3. EDWARDS, RICHARD New Jersey Department of Children & Families $1,649,000.00School of Social Work

4. GIESE, MARY LOU New Jersey Department of Community Affairs $1,500,000.00Bloustein Center for Government Services

5. MAHER, ALI New Jersey Department of Transportation $1,300,000.00Civil &Environmental Engineering

CORPORATIONS

1. PLINIO, ALEX J Prudential $2,000,000.00RU Business School Organization Mgmt

2. RIMAN, RICHARD CCS Materials, Inc. $1,212,753.00Center for Ceramics Research

3. BARONE, JOSEPH Hoffmann-LaRoche Inc. $1,041,390.00Pharmacy Practice & Administration

4. BARONE, JOSEPH Merck & Co $1,041,390.00Pharmacy Practice & Administration

BARONE, JOSEPH Novartis Pharmaceuticals $1,022,280.00Pharmacy Practice & Administration

ASSOCIATIONS/FOUNDATIONS

1. TISCHFIELD, JAY A Simons Foundation $8,590,469.40Human Genetics Institute

2. MILLER, JANE E Robert Wood Johnson Foundation $2,370,658.00Institute for Health

3. HARTLING, GRETCHEN TS Robert Wood Johnson Foundation $994,860.00Institute for Health

4. YEDIDIA, MICHAEL J Robert Wood Johnson Foundation $759,998.00Institute for Health

5. VANDENBERGHE, EDUARD Alfred P. Sloan Foundation $750,000.00Institute of Marine & Coastal Sciences

39

Largest Single Projects by PI: Top Twenty

PI/Related Unit Sponsor / Project Title Award

1. TISCHFIELD, JAY A National Institutes of Health $20,124,323.00Human Genetics Institute NIMH Center for Collaborative Genetic Studies

2. MONTELIONE, GAETANO T National Institutes of Health $12,592,442.00Ctr Adv Biotechnology & Medicine Structural Genomics of Eukaryotic Domain Families

3. TISCHFIELD, JAY A National Institutes of Health $9,492,078.00Human Genetics Institute Rutgers University Cell and DNA Repository Renovation

4. TISCHFIELD, JAY A Simons Foundation $8,590,469.40Human Genetics Institute Simons Complex Collection

5. EDWARDS, RICHARD New Jersey Department of Human Services $8,556,601.00Institute for Families New Jersey Child Support Training Institute

6. PALMER, DEBRA US Department of Agriculture $7,116,243.00Administration & Central Services NJ Food Stamp Nutrition Education

7. BERMAN, HELEN M National Science Foundation $6,382,943.00Chemistry & Chemical Biology PDB Management by the Research Collaboratory for Structural Bioinformatics

8. BARON, JERRY J US Department of Agriculture $6,302,679.00Office of IR-4 IR-4 Minor Crop Pest Management

9. MAHER, ALI US Department of Transportation $5,650,000.00Ctr Adv Infrastructure & Transportation Long Term Bridge Performance Program

10. TISCHFIELD, JAY A National Institutes of Health $4,753,341.00Genetics NIDA Center for Genetic Studies

11. LARROUSSE, PAUL J US Department of Transportation $4,300,000.00Bloustein - National Transit Institute US DOT-FTA-NTI Transit Training

12. ROBERTS, FRED S US Department of Homeland Security $3,797,499.00DIMACS Center of Excellence for Command, Control, and Interoperability

13. MUZZIO, FERNANDO J National Science Foundation $3,750,000.00Bureau of Engineering Research The Center for Structured Organic Composites (C-SOC) for Pharmaceutica Nutraceutical

14. EDWARDS, RICHARD New Jersey Department of Children and Families $3,500,000.00School of Social Work The New Jersey Partnership for Child Welfare Program

15. GLENN, SCOTT M US Department of Commerce-NOAA $3,486,000.00Inst of Marine & Coastal Sciences Phased Deployment & Operation of the Mid-Atlantic Regional Coastal Ocean Observing System

16. MAHER, ALI U.S. Department of Transportation $3,000,000.00Ctr Adv Infrastructure & Transportation Heavy Load Vehicle Simulator for Bridge Deck Testing Application

17. HOPPER, BRENDA B Small Business Administration $2,994,605.00Graduate School of Management New Jersey Small Business Development Center

18. BERMAN, HELEN M National Institutes of Health $2,455,892.00Chemistry & Chemical Biology The Protein Structure Initiative Knowledgebase

19. TISCHFIELD, JAY A National Institutes of Health $2,427,078.00Human Genetics Institute Integration of Genomics & Transcriptomics in Normal Twins & Major Depression

20. MILLER, JANE E Robert Wood Johnson Foundation $2,370,658.00Institute for Health Internship to Diversify Perspectives in Health Research

40

41