REPURPOSING PHARMACEUTICAL FACILITIES TO CREATE PRODUCTIVE ASSETS DELIVERING PROJECTS USING AN INTEGRATED PROGRAM MANAGEMENT SYSTEM

OBG | www.obg.com

Robert F. Patullo - Vice President

Decontamination and Demolition Master Planning and Implementation

� 7-million ft2 R&D and pharmaceutical manufacturing complex

� Strategic facility consolidation and repurposing plan

� Decontamination, demolition, and redevelopment of multiple buildings

� Design and integration of facilities and utilities infrastructure

� Hazardous waste removal

Building Suite Decontamination and Demolition

� Decontamination and demolition of former drug manufacturing suite within existing active facility

� Environmental health and safety plan � Plan for removal of production equipment without impacting operations

� Developed SOPs and self performed all work to prevent contamination

Equipment Removal � Building within a large pharmaceutical R&D campus

� Removal of four 1940s era boilers without impacting operation of two steam turbines

� Hazardous waste abatement � Removal of mechanical and electrical appurtenances

� Newly restored space will support a third steam turbine to generate additional, more efficient power for the campus

The pharmaceutical industry has been going through major restructuring based on business conditions and market demand. This has resulted in mergers and acquisition activity and the need for subsequent repurposing of assets ranging from cGMP suites to full research/manufacturing buildings, to a site wide campus.

OBG has addressed more than $125 million and 25 million square feet of projects for the pharmaceutical industry, providing decontamination through redevelopment at hundreds of sites, from small manufacturing process suites to 2,000-acre campuses.

Based on years of experience providing strategic master planning, estimating and scheduling, design, implementation, and reuse processes for several plant closures and consolidation projects, lessons learned include:

� Focusing on industry requirements within manufacturing spaces � Remaining flexible to changes in market dynamics and end uses for the site(s) � Forging key partnerships in niche areas, such as regulatory specialties and permitting for demolition, and working with partners up front to assemble the right teams with proven experience

A proven, industry-specific process and approach has been developed to assist pharmaceutical industry clients with their repurposing projects. This approach has been utilized for more than 125-million square feet of manufacturing space on pharmaceutical campuses in the past seven years. Integral to the approach is the up-front planning of the projects, including elements such as:

� Taking into account the manufacturing environment and community � End use vision for the site(s) � Client standard operating procedures (SOPs) and planning process � Health & Safety planning and processes with zero incident occurrence � Facility-specific decontamination considerations based on active pharmaceutical ingredients (APIs)

� Strong project management – including people power, safety, scheduling, and budgeting

� Utilization of a proven CM team to implement the project � Project teams that remain flexible to adapt to the changing dynamics of the pharmaceutical market

APPROACH / ACTIVITIESBACKGROUND AND OBJECTIVES

RESULTS / LESSONS LEARNED

WEST POINT, PARAHWAY, NJ

Decontamination and Demolition Support

� Plan for decontamination, decommissioning, and demolition of a production facility

� Plan for utility decontamination, decommissioning, and removal

ELKTON, VA

Campus Decontamination and Demolition

� 4-million ft2 former pharmaceutical manufacturing plant

� Construction management (CM) for complete structural demolition and redevelopment

� Utility removal � Asbestos and lead abatement � Waste management and recycling

Received 2014 National Demolition Association Environmental Excellence Award

ALBANY, GA