REPORT - ISWSI 1st INTERNATIONAL SYMPOSIUM AND WORKSHOP ON SPECTRAL IMAGING: ......

REPORT1 s t I N T E R N A T I O N A L S Y M P O S I U M A N D W O R K S H O P O N S P E C T R A L I M A G I N G :

A P P L I C A T I O N S I N B A S I C S C I E N C E S A N D B I O M E D I C A L R E S E A R C H

OCTOBER 18 - 20, 2013

I S W S I 2 0 1 3Kohinoor Bal lroom, Majest ic Park Plaza, Ludhiana, Punjab

B e t t y C o w a n R e s e a r c h a n d I n n o v a t i o n C e n t r e , C h r i s t i a n M e d i c a l C o l l e g e a n d H o s p i t a l , L u d h i a n a , P u n j a b -

1 4 1 0 0 8 • t e l e p h o n e / f a x : + 9 1 - 1 6 1 - 5 0 8 6 0 0 4 • w w w. i s w s i . i n • w w w. b c r i c . i n • w w w. c m c l u d h i a n a . i n

“The real role of leadership is climate control - creating a climate of

possibility. If you do that, people will rise to it and achieve things that

you completely did not anticipate and couldn’t have expected”

- Sir Kenneth Robinson -

(Author, Speaker and International Advisor on Education, Creativity and Innovation)

© NDSK BCRIC 2013

All images, logos, and designs are the sole property of the organizer. No reproduction will be

permitted without prior written approval.

We believe in

Science + Service

to

Society

Table of contents

Introduction 1

List of Speakers 2

Brief bio on the speakers 2

Yuval Garini, PhD. 2

T Pradeep, PhD. 2

Nir Katzir, MSc. 3

James Burger, PhD. (Delivered live presentation and workshop via Skype) 3

Prasanth Perugupalli 3

Bhushan Dhakras 3

Asher Srigiri 4

Manjeet Kaur Sangha, PhD. 4

Neeta D Sinnappah-‐Kang, DBiol. 4

Background disciplines of participants 5

The composition of the participants 6

Locations for student participants 7

List of participants 8

Benefits of organizing the event 10

Press coverage 11

October 19, 2013 11

Punjab News Live (online) 11

October 20, 2013 12

Ajit (#1 Punjabi Newspaper) 12

October 20, 2013 (continued ...) 13

Ludhiana Savera (Hindi Newspaper) 13


Ludhiana Kesari (Hindi Newspaper) 14


Dainik Jagran (Hindi Newspaper) 15

Daily Ludhiana 15

October 21, 2013 16

Ajit (#1 Punjabi Newspaper) 16

Acknowledgements 17

Photos from the ISWSI 18

C h r i s t i a n M e d i c a l C o l l e g e a n d H o s p i t a l , L u d h i a n a

I S W S I 2 0 1 3 R E P O RT


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“Education is the most powerful weapon which you can use to change the world”

– Nelson Mandela

Introduction

! The 1st International Symposium and Workshop on Spectral Imaging: Applications in Basic Sciences and Biomedical Research, was held on October 18-20, 2013 at Kohinoor Ballroom, Majestic Park Plaza (Ludhiana, Punjab, India). This was the first time such an event was organized in India, and I believe, internationally, to focus on applications of Spectral Imaging in the areas of Basic Sciences and Biomedical Research. It was the first attempt at bridging the gap between multiple disciplines and applications. The workshop presented a unique platform for teaching current applications while allowing the participants to get hands-on experience at working with their samples. It was inaugurated by Dr. Abraham G Thomas, Director, Christian Medical College and Hospital, Ludhiana.

! Science is advancing at such a fast pace that it becomes virtually impossible to keep up without collaborations. The advances in spectral imaging have shown their potential in many areas, such as cancer research, basic pathology, nano-bioresearch, cell biology, plant sciences, bacteriology, and forensic research, to name a few. Understanding what others have achieved successfully in their respective applications and "translocating" those same ideas into another field (of course, with some fine-tuning) could help speed up what we need to achieve ourselves in our respective domains.

! Our goals for the workshop were not only to help participants understand the theory, applications and potential of spectral imaging, but also to choose the appropriate imaging system and consumables for their application, which included proper microscope/lens setup and access to the list of consumables in the market to help make their progress in research smooth.


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“Many of life’s failures are people who did not realize how close they were to

success when they gave up.”

- Thomas Edison

“What counts in life is not the mere fact that we have lived. It is what difference we have

made to the lives of others that will determine the significance of the life we lead.”

- Nelson Mandela

Students taking notes during the lectures.

Panel discussion.

Postgraduate students asking questions.(L: from PAU; R: from NIPER)

List of Speakers

Name Institution/Company (Country)National/

International

1 Prof. Dr. Thalappil PradeepIndian Institute of Science, Madras

(INDIA)National

2 Mr. Prasanth Perugupalli IMEC-India, Bangalore (INDIA) National

3 Dr. Manjeet Kaur SanghaPunjab Agricultural University,

Ludhiana (INDIA)National

4 Mr. Bhushan Dhakras Pixelteq, Mumbai (INDIA) National

5Dr. Neeta Devi Sinnappah-

Kang

Christian Medical College and

Hospital, Ludhiana (INDIA)National

6 Prof. Dr. Yuval Garini Bar-Ilan University, Ramat Gan (ISRAEL) International

7 Mr. Nir KatzirApplied Spectral Imaging, Yokneam

(ISRAEL)International

8 Dr. James Burger BurgerMetrics SIA, Riga (LATVIA) International

Brief bio on the speakers

Yuval Garini, PhD.Yuval Garini acts as an Associate Professor at the Physics Department and the Institute of

Nanotechnology at Bar-Ilan University since 2006. His work is centered in studying physical properties of biological systems by using optical microscopy and spectroscopy methods, including the use of nano-structures and single molecule detection methods. He is heading a group of about 10 graduate and undergraduate students, teaching courses in the fields of advanced optical microcopy, Biophysics and Nanoscience and author of dozens of scientific publications. Yuval

graduated his PhD in Physics at the Technion in Israel working on optical properties of quantum structures. He then established a startup company and developed spectral imaging systems for biomedical applications, including spectral karyotyping (SKY) that is used all around the world for research and diagnostics. In 2002 he became an assistant professor at the Applied Sciences Department in Delft University, The Netherlands.

T Pradeep, PhD.T. Pradeep is a Professor of Chemistry at the Indian Institute of Technology Madras, Chennai, India. He earned his PhD. from the Indian Institute of Science in 1991 and had post doctoral training at the Lawrence Berkeley Laboratory, University of California, Berkeley and Purdue University, West

Lafayette. He held visiting positions at many leading universities and institutes in Asia and Europe. His research interests are in molecular and nanoscale materials and he develops instrumentation for those studies. He has authored 285 scientific papers in journals and is an inventor in 50 patents or patent applications. He is involved in the development of affordable technologies for drinking water purification. Some of his technologies have been commercialized. Along with his associates,

he has incubated a company. He is a recipient of several awards including the Shanti Swaroop Bhatnagar Prize, BM Birla Science Prize, National Award for Nanoscience and Nanotechnology and the India Nanotech Innovation Award. He is an adjunct professor at the Institute of Life Sciences, Ahmedabad University and PSG Institutes of Advanced Study, Coimbatore. He is a Fellow of the


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Indian Academy of Sciences. He is the author of the introductory textbook, Nano: The Essentials (McGraw-Hill) and is one of the authors of the monograph, Nanofluids (Wiley-Interscience) and an advanced textbook, A Textbook of Nanoscience and Nanotechnology (McGraw-Hill).

Nir Katzir, MSc.Nir Katzir was a member of Applied Spectral Imaging's founding team in 1993. Since then, he has managed key projects and played a major role in the design and the development of ASI's unique products and applications. As an ASI executive leading the Research and Development activity of

ASI, he is in charge of the algorithms that form the substructure of the company's intellectual property. He is the co-author of many of ASI's patents and papers. Prior to 1993, Mr. Katzir worked on a PhD at a prestigious Institute of Technology. He received his MSc. degree in Electrical Engineering and BSc degree in Computer Engineering, both summa cum laude. He specialized in computer vision, image analysis, and spectral and multi-dimensional imaging. Mr. Katzir was

awarded several prizes, fellowships and honors, such as the P. Martin Excellence Award, the Ollendorf Award for excellence in the field of image analysis, the Jury Award, the Gutvirt Scholarship, and many teaching awards.

James Burger, PhD. (Delivered live presentation and workshop via Skype)

James Burger, the founding Director of SIA BurgerMetrics, is a leading specialist in chemical imaging research with over 35 years of experience in the development of analytical chemistry instrumentation and scientific workstation software applications. Dr. Burger completed a PhD. degree at the Swedish University of Agricultural Sciences, Umea, Sweden, focusing on theoretical aspects of hyperspectral imaging. He was awarded the 2008 Gerald Birth Award for outstanding

publication in diffuse spectroscopy, based on his doctoral thesis entitled “Hyperspectral NIR Image Analysis: Data Exploration, Correction, and Regression”. After completing his PhD. Dr. Burger recognized the need for the development of expert chemical analysis software for hyperspectral imaging and in 2007 formed BurgerMetrics. The company is now a world leader in the development of hyperspectral chemical imaging, including both image analysis software, and

customized fully integrated imaging system hardware. Its products can be used in an unlimited range of research or industrial applications, spanning airborne, macro, and microscopic spatial domains and visible through infrared (IR) spectral domains.

Prasanth Perugupalli

Prasanth Perugupalli is the Director of R&D at IMEC-India lab in Bangalore. He has a master's degree in semiconductor device physics from University of Illinois at Chicago and 16 years of experience in the field of semiconductor devices and wireless communications. Most recently, he managed the technology development of 7Gbps WiFi technology at Broadcom Corporation and was the board member of the Wireless Gigabit Alliance. IMEC is a semiconductor research organization from

Leuven, Belgium that is bringing semiconductor process technology to address problems in imaging, healthcare and life sciences. IMEC India is working with these technologies to target specific applications such as diagnosis of diabetes and eye diseases, skin care, etc. They use hyperspectral imagers extensively to gather signatures from pathology samples, human skin, wounds, etc and develops algorithms to extract spectral information and build classification

frameworks. Prasanth also facilitates R&D collaboration opportunities with other IMEC teams worldwide that are involved in development of technologies such as micro-PCR, MEMS, Image sensors, Body sensors, lens free imaging, mmWave technology, etc.

Bhushan Dhakras

Bhushan Dhakras is the Business Development Manager for PIXELTEQ in India. He has a strong background in the manufacture and technical sales of high tech instruments used in the Optics, Electrical, Automotive & Semiconductor Industry. He is a valued member of the PIXELTEQ team with


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a total experience of more than 15 years in technical sales. He is an important support resource for developing partnerships with academic labs, researchers & high tech OEM’s. Bhushan holds a Mechanical Engineering and Business Management Degree from Mumbai University. He uses his

expertise in promoting the unique Multi-Spectral technology of Pixelteq for various applications and research projects in India like Biomedical Science, Cancer Research, Agriculture, Forensic, Art Conservation, to name a few. Pixelteq specializes and offers dichroic optical filters and precision optics for scientific, defense, metrology and entertainment applications. It is known for its patented precision pixel technology and aims to take multi-spectral imaging to the next level.

Asher SrigiriAsher Srigiri has a masters in Business Management and is presently working with Amigo Optima Software Solutions Pvt Ltd.. Hyderabad as its Director of Sales. Amigo Optima is into providing end to end bespoke solutions for the education, research and commercial markets in the field of Imaging.

He started his career in market research with Dalmia group in New Delhi and later moved into a career in sales. During 24 years of his career in sales, he has been actively involved in sale of products and projects in the technology areas such as HVAC, Telecom, Environment, IT and Imaging, of which, a decade into the Hyperspectral Imaging Solutions including analytical software development in Indian market. He is associated with various organizations in Defense, Agriculture,

Forensics’, CSIR labs, Pharma Industry, Multinational R&D establishments, Indian Space Research Organizations, to name a few, and is closely involved in ongoing projects with Defense Research Organizations, Agriculture Research, ISRO, Pharma Industry for the last five years.

Manjeet Kaur Sangha, PhD.

Dr Manjeet Kaur Sangha is working as Associate Biochemist in the Department of Biochemistry, Punjab Agricultural University (PAU), Ludhiana. She got her MSc and PhD degrees, in 1988 and 1993 respectively, from Postgraduate Institute of Medical Education and Research, Chandigarh. She worked as Research Fellow, in an ICAR Adhoc scheme for two years from 1996-98, in Department of Farm, Power and Machienery, PAU, Ludhiana. She worked on the production and

characterization of Biodiesel from various plant oils for their use in Compression Ignition engines. She joined as Assistant Biochemist in the Department of Biochemistry, PAU, Ludhiana in 1998. She worked on characterization of extracellular enzymes of fungus Botrytis cinerea and estimated defensive enzymes of chickpea against Botrytis cinerea. She estimated and characterized lectins from lentil cultivars differing in their nodulation ability. She also worked as Assistant and Associate

Biochemist in Oilseed Section, Department of Plant Breeding and Genetics, PAU, Ludhiana. She evaluated Brassica germplasm for various nutritional and anti-nutritional traits viz. oil content, fatty acid composition, tocopherols, carotenoids, proteins, sinapine and glucosinolates. She prepared near-infrared (NIR) calibration equation for estimation of various traits of Brassicas in one go. She also studied the role of lectins as entomotoxic proteins against mustard aphid and purified lectins

from various non-Brassica sources and tested their efficacy against mustard aphid. She worked on quality evaluation of some cotton genotypes. Presently, she is screening cotton genotypes for salinity tolerance and trying to study biochemical traits responsible for salinity tolerance. She has guided seven MSc and two PhD students and is teaching various courses of Biochemistry. She has two research projects to her credit as Principle Investigator. She has twenty five research

publications in national and international journals of repute.

Neeta D Sinnappah-Kang, DBiol.Neeta Sinnappah-Kang is Head and Senior Scientist at Betty Cowan Research and Innovation Centre, Christian Medical College and Hospital, Ludhiana. She was a Research Investigator at the

Division of Pediatrics, MD Anderson Cancer Centre (Houston, Texas, USA) before coming to India. Dr. Neeta D Sinnappah-Kang received her Bachelors in Science with Honors in Biochemistry from University Malaya in 1992. She went on to receive her Master of Biotechnology from the same


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university in 1995 in the area of Algal Molecular Systematics. Dr. Kang received her Doctor of Biology in Molecular Evolution and Parasitology from the Centre of Tropical and Mediterranean Biology and Ecology, National Centre for Scientific Research, University of Perpignan (France) in

1998. She was a CNOUS scholarship holder from the French Government. Her research experience included work she conducted in labs in Canada and Spain in addition to other labs in France. She joined as a Lecturer at the Faculty of Science and Technology, The National University of Malaysia from 1999 - 2002. She completed her postdoctoral training in pediatric brain tumor biology at the Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State

University, Baton Rouge (USA) from 2003 - 2006. Dr. Kang became a Research Investigator at Division of Pediatric, Children’s Cancer Hospital, MD Anderson Cancer Centre (USA) from 2006 - 2007. In 2006, she attended a course on “Neuronal Differentiation and Brain Tumors” at Cold Spring Harbor, New York (USA) and received a stipend award. In November 2007, Dr. Kang joined as the Head of Innovation at the newly built Betty Cowan Research and Innovation Centre, Christian

Medical College and Hospital (ranked among the top 5% of Medical Colleges in India), Ludhiana. Since 2009, she has brought in a total of USD$250K in funding towards research and infrastructure building. She has built a state-of-the-art, environmentally-friendly, molecular research laboratory from zero. Her recent success is her largest grant from Sir Ratan Tata Trust and Navajbai Ratan Tata Trust (one of the largest philanthropic organizations in India) for the purchase of a Hyperspectral

Imaging System. She has more than 21 years of combined experience in the fields of molecular biology, bioinformatics and biochemistry. In addition, she has 10 years of experience in the field of cancer biology, drug testing and microRNAs. Since 2009, she has been using multispectral imaging and has now started working on hyperspectral imaging as a technology for her current ongoing research work on different biomedical applications.

Background disciplines of participants

We welcomed participants from the following disciplines/research interest:

1. Biochemistry2. Bioinformatics3. Biophysics

4. Biotechnology5. Cancer Biology6. Chemistry7. Cytogenetics8. Engineering

9. Medicine10. Nanotechnology11. Pharmacology12. Plant Sciences13. Stem Cell Research


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The composition of the participants

The participants (including speakers) are divided into the following categories: Faculty (Academia), Students (Academia), Industry (Non-profit) and Industry (For profit).

The students represented close to 50% of the group of participants.

19%

9%

48%

24%

Faculty (Academic)Students (Academic)Industry (Non-profit)Industry (For profit)


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“Anyone who has never made a mistake has never tried anything new.”

– Albert Einstein (1921 Nobel Prize in Physics)

“The world as we have created it is a process of our thinking. It cannot be changed without changing our thinking.”


Locations for student participants

Map of India with location (at the state level) of student participants (represented by small red stars).


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List of participants

The table below lists the name of the participants, their institution or company and category.

Name Institution/Company Category

1 Dr. Guramrinder Singh ThindSDM College of Medical Sciences and

Hospital, DharwadStudent

2 Mr. Kanav KheraManipal College of Pharmaceutical

Sciences, ManipalStudent

3 Mr. Ashish Joel Joseph Karunya University, Coimbatore Student

4 Mr. Prasanth Perugupalli IMEC-India, Bangalore Industry

5 Mr. Sumit Nath Kumar IMEC-India, Bangalore Industry

6 Mr. Raghubansh Gupta IMEC-India, Bangalore Industry

7 Dr. Jarnail SinghNational Institute for Research in

Reproductive Health, Mumbai

Post-doctoral

fellow

8 Dr. Anu Kalia Punjab Agricultural University, Ludhiana Faculty

9 Ms. Gagandeep Kaur Punjab Agricultural University, Ludhiana Student

10 Dr. Rajinder ChawlaChristian Medical College and Hospital,

LudhianaFaculty

11 Mr. Bhushan Dhakras Pixelteq, Mumbai Industry

12 Mr. Krishna Singh Pixelteq, Mumbai Industry

13 D. Prabhu Eletrotek International Inc., Chennai Industry

14 Ms. Kumari Anupam Punjab University, Chandigarh Student

15 Mr. Ganesh SheteNational Institute of Pharmaceutical

Education and Research, MohaliStudent

16 Mr. Asher Srigiri AmigoOptima, Hyderabad/New Delhi Industry

17 Ms. Jyoti Shree AmigoOptima, Hyderabad/New Delhi Industry

18 Ms. Apinder Kaur Punjabi University, Patiala Student

19 Ms. Amandip Kaur Punjabi University, Patiala Student

20 Ms. Nisha Bhatia Punjab University, Chandigarh Student

21 Ms. Shashi Bala Punjab University, Chandigarh Student

22 Ms. Jasmine Sati Punjab University, Chandigarh Student

23 Ms. Nisha Gautam Punjabi University, Patiala Student


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Name Institution/Company Category

24 Mr. Ajay Francis ChristopherChristian Medical College and Hospital,

Ludhiana

Research

Associate

25 Ms. Simranjeet KaurChristian Medical College and Hospital,

Ludhiana

Project

Assistant

26 Ms. Veena RawatChristian Medical College and Hospital,

Ludhiana

Project

Assistant

27 Dr. Parveen BansalBaba Farid University of Health Sciences, Faridkot

Faculty (Joint-

Director, UCER)

28 Dr. Surinder Singh Banga Punjab Agricultural University, Ludhiana Faculty

29 Dr. Manjeet Kaur Sangha Punjab Agricultural University, Ludhiana Faculty

30 Dr. Yuval Garini Bar-Ilan University, Ramat Gan (Israel) Faculty

31 Dr. Thalappil Pradeep Indian Institute of Science, Madras Faculty

32 Mr. Nir KatzirApplied Spectral Imaging, Yokneam

(Israel)Industry

33 Dr. Neeta D Sinnappah-KangChristian Medical College and Hospital,

LudhianaFaculty


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“I have no special talents. I am only passionately curious”


Benefits of organizing the event

By bringing together people from academia, industry and students on a single platform, the following benefits were observed during the two and a half days event:

1. we brought speakers who had extensive background in spectral imaging from various

fields (spectral karyotyping, biophysics, nano bioresearch, plant sciences, cancer research and pathology, to name a few) and the participants benefited immensely from their lectures and one-on-one interactions with them.

2. there was networking among the speakers, industry people, and students.

3. the half-a-day workshop gave the participants an opportunity to actually see the imaging

systems in action and this had an impact on understanding the technology in real-time, which enhanced what they learnt from the two days of lectures.

4. the speaker from Indian Institute of Technology Madras (Dr. T Pradeep, IIT Madras) has offered to host the next ISWSI at his institution in Chennai in 2014 and it will be theme-based.

5. almost 50% of the participants were postgraduate students. They are the future scientists and will take this technology further in different fields of study.

6. one of the most crucial point from organizing such a focused event was that everyone who attended it gave it their 100% attention. Those who brought their samples and participated in the workshop were very happy to see how spectral imaging could be

beneficial for their research.

7. the event was a win-win situation for those from academia and industry.

8. the sponsors were very happy with the outcome of the event that they have indicated their interest in being part of the group and part of all future events.


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Press coverage

October 19, 2013

Punjab News Live (online)


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October 20, 2013

Ajit (#1 Punjabi Newspaper)


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October 20, 2013 (continued ...)

Ludhiana Savera (Hindi Newspaper)


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Ludhiana Kesari (Hindi Newspaper)


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Dainik Jagran (Hindi Newspaper)

Daily Ludhiana


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October 21, 2013

Ajit (#1 Punjabi Newspaper)


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Acknowledgements

We would like to acknowledge the following exhibitors for sponsorship:

• DSS Imagetech Pvt Ltd

• Pixelteq

We would like to acknowledge our online partners:

We would like to acknowledge and thank the following people from Christian Medical College and Hospital, Ludhiana:

Dr. Abraham G Thomas, DirectorDr. SM Bhatti, Principal Medical CollegeDr. Kanwal Masih, Medical SuperintendentMr. Amit Aggarwal, Finance OfficerMr. Prabakaran, Finance Office

Mr. Unnikrishnan Nair, Department of Medical InformaticsMr. Satish Nair, Department of Medical InformaticsMr. Param Veer Singh, Public Relations/Marketing CoordinatorMs. Amarjeet Kaur, Media PersonMr. Avtar and Mr. Yunus (CMCL’s photographer)

Fellowship Department

The Spectra-View Hyperspectral Imaging System of Betty Cowan Research and Innovation Centre, Christian Medical College and Hospital, Ludhiana was supported by a grant from Sir Ratan Tata Trust and Navajbai Ratan Tata Trust. The HSI system was used during the workshop.

We thank our travel partner: MakeMyTrip


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Photos from the ISWSI


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Dr. Yuval Garini, Bar-Ilan University (Israel)

Dr. Manjeet Kaur Sangha, PAU (India)

Dr. Neeta D Sinnappah-Kang, CMCH (India)

Mr. Asher Srigiri, AmigoOptima (India)

Dr. T. Pradeep, IIT Madras (India)

Mr. Prasanth Perugupalli, IMEC (India)

Mr. Nir Katzir (centre), ASI (Israel)

Mr. Bhushan Dhakras, PIXELTEQ (India)

PIXELTEQ (Exhibitor Booth)

Workshop in progress


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Contact info:Dr. Neeta D Sinnappah-‐Kang

Betty Cowan Research and Innovation CentreChristian Medical College and Hospital

Brown Road, LudhianaPunjab -‐ 141008

INDIATel/Fax: +91-‐161-‐5086004

[email protected]

www.cmcludhiana.in

REPORT - ISWSI 1st INTERNATIONAL SYMPOSIUM AND WORKSHOP ON SPECTRAL IMAGING: ......

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