Remembered Questions for Step 1 Usmle Forum

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Remembered questions for STEP 1 - USMLE Forum http://www.usmleforum.com/files/forum/2007/1/193828.php[11/7/2011 2:10:26 PM] USMLE Forum Step 1 Step 2 CK Step 2 CS Matching & Residency Step 3 Miscellaneous Archives << < * Step 1 * > >> * Remembered questions for STEP 1 #193828 nassab - 06/12/07 04:05 This is the compilation or remembered questions. Many you might have it but thought it might help the new comers pharmocology: 1. SE of Cyclophosamide: h. cystitis 2. Tx of h. cystitis: MESNA 3. Tx of Pnumonia 4. MOA of Gancyclovir 5. MOA of Vincristine 6. MOA of Metotrexate 7. Prozosine...BPH, alpha1, HTN 8. Action potential curve...Ca++ channels closed 9. Cefataxime , indication 10. MOA of Glybride 11. Rifampin: tx for TB pt. 12. Asked x drug (warferin) MOA: acts like anti vit-K drug(choice) 13. Identify Partial antagonist on the graph 14. MOA of Colchicine 15. Tx for tonic clonic seizure? 16. Tx for a Kid with absent seizure beside ethosuximide? 17. Tx for a pt. with depression? Phenelzine 18. Furosemide : pick the correct area affected on the diagram of nephron. 19. Dopamin affects what NT? Ephineprine, NE, ... 20. What drug is given post MI? I picked Aspirine 21. Tx for sleep apnea? methylamphedamine 22. MOA of Cocaine 23. Ketoconazole? 24. MOA of AZT? 25. Tx for a pt with fever, productive cough, greenish sputum? 26. MOA of Rifampin? inhibits what assembly? 27. MOA and SE of Amphotrecine? 28. MOA of Gentamicine? Ristricts polysome formation 1. A pt has orchitis and has decreased libido how do you treat him? (Testosterone, hCG, I cann’t see the other choices) 2- a man and a woman have autosomal doiminant disease got married, If you know that they have natural stature, which disease of the following, their children have a big chance to get it: cystic fibrosis b- achondroplasia c- MELAS. 3- what happened if the dashed part is affected (look at the diagram at Q3) many choices I choose loss of vibration an touch. 4- A girl got sore throat and was treated with penicillin without improvement, after sometime she died with heart problems, what is the cause? a. cocci b. CMV c. coxackie virus. 5- Viruses that carry virion associated polymerase what is the enzyme that is not found in the cytoplasm and this enzyme is used instead? a. DNA dependant DNA polymerase b. DNA dependant RNA polymerase c. RNA dependant RNA polymerase. 6- What do we need for PCR? a.deoxyribonuleotide b. DNA ligase. 7- How does mRNA exit the nuleouse? Transport dependant on ATP 8- What produce superoxide? a. superoxide dismutase b. NADPH oxidase c. catalase d. glutathione peroxidase

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Rememberedquestions for STEP 1

193828 nassab - 061207 0405

This is the compilation or remembered questions Many you might haveit but thought it might help the new comers

pharmocology1 SE of Cyclophosamide h cystitis 2 Tx of h cystitis MESNA3 Tx of Pnumonia4 MOA of Gancyclovir5 MOA of Vincristine6 MOA of Metotrexate7 ProzosineBPH alpha1 HTN8 Action potential curveCa++ channels closed9 Cefataxime indication10 MOA of Glybride11 Rifampin tx for TB pt12 Asked x drug (warferin) MOA acts like anti vit-K drug(choice)13 Identify Partial antagonist on the graph14 MOA of Colchicine15 Tx for tonic clonic seizure 16 Tx for a Kid with absent seizure beside ethosuximide17 Tx for a pt with depression Phenelzine18 Furosemide pick the correct area affected on the diagram ofnephron19 Dopamin affects what NT Ephineprine NE 20 What drug is given post MI I picked Aspirine21 Tx for sleep apnea methylamphedamine22 MOA of Cocaine23 Ketoconazole24 MOA of AZT25 Tx for a pt with fever productive cough greenish sputum26 MOA of Rifampin inhibits what assembly27 MOA and SE of Amphotrecine28 MOA of Gentamicine Ristricts polysome formation1 A pt has orchitis and has decreased libido how do you treat him(Testosterone hCG I cannacirceurotradet see the other choices)

2- a man and a woman have autosomal doiminant disease got marriedIf you know that they have natural stature which disease of thefollowing their children have a big chance to get it cystic fibrosis b-achondroplasia c- MELAS

3- what happened if the dashed part is affected (look at the diagram atQ3) many choices I choose loss of vibration an touch

4- A girl got sore throat and was treated with penicillin withoutimprovement after sometime she died with heart problems what is thecause a cocci b CMV c coxackie virus

5- Viruses that carry virion associated polymerase what is the enzymethat is not found in the cytoplasm and this enzyme is used instead aDNA dependant DNA polymerase b DNA dependant RNA polymerase cRNA dependant RNA polymerase

6- What do we need for PCR adeoxyribonuleotide b DNA ligase

7- How does mRNA exit the nuleouse Transport dependant on ATP

8- What produce superoxide a superoxide dismutase b NADPHoxidase c catalase d glutathione peroxidase

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9- A boy has deficiency of skull mineralization what is affected afibrillin b chondroiin c collagen d heparin sulfate

10- A pt has kidney stones how do you treat him a mannitol bfurosemide c spironolactone d hydrochlorothiazide e indapamide11- Not clear12- Not clear13- MRI of brain with a mass in the ventricle this tumor most probablyfrom a melanocyte b epithelial cells c meningioma14- Q about apoptosis

15- A labeled draw of virus infecting a cell asked about which level dothe nucleoside RT inhibitors affect16- A pt had heart transplant and now is treated with cyclosporinethen he got respiratory problem with decreased lung functions what isthe cause a CMV b PCP17- A pt has cardiac tamponade what do you see under microscopeafter two hours prove that itacirceurotrades irreversible injury A acute swellingof mitochondria b acute swelling of plasma membrane c migration ofnucleus18- What is the most important factor for otitis externa APaeurginosa b S pneumoniae19- A female with STD she has microorganism covering skin cells andclue cells what is the diagnosis A candida b trichomonas c bacterialvaginosis20- Two girls 16 and 14 years old came to you the 14 years girl hasSTD what is your next step A treat her with permission of her oldersister b treat her without permission c treat her with her parentspermission21- A pt with cancer in need to surgery but his response is that acirceuroœwhat is the benefit if Iacirceurotradem gonna die soonacirceuro your response is Aask him to go and get help b show him cases with the same disease sohe can agree for surgery

11- Not clear12- Not clear13- MRI of brain with a mass in the ventricle this tumor most probablyfrom a melanocyte b epithelial cells c meningioma14- Q about apoptosis

15- A labeled draw of virus infecting a cell asked about which level dothe nucleoside RT inhibitors affect16- A pt had heart transplant and now is treated with cyclosporinethen he got respiratory problem with decreased lung functions what isthe cause a CMV b PCP17- A pt has cardiac tamponade what do you see under microscopeafter two hours prove that itacirceurotrades irreversible injury A acute swellingof mitochondria b acute swelling of plasma membrane c migration ofnucleus18- What is the most important factor for otitis externa APaeurginosa b S pneumoniae19- A female with STD she has microorganism covering skin cells andclue cells what is the diagnosis A candida b trichomonas c bacterialvaginosis20- Two girls 16 and 14 years old came to you the 14 years girl hasSTD what is your next step A treat her with permission of her oldersister b treat her without permission c treat her with her parentspermission21- A pt with cancer in need to surgery but his response is that acirceuroœwhat is the benefit if Iacirceurotradem gonna die soonacirceuro your response is Aask him to go and get help b show him cases with the same disease sohe can agree for surgery

Viruses that carry virion associated polymerase what is the enzyme thatis not found inthe cytoplasm and this enzyme is used instead a DNA dependant DNApolymerase b DNAdependant RNA polymerase c RNA dependant RNA polymerase

Re2007 Crush Bank 653475 ericvorheese - 020907 1935

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great idea heres my contributionan experience from a test thatwas taken earlier this week -

Biochem some key enzyme deficiency ones (Lesch Nyhan Maple SyrupDisease) but all of the questions were very obvious and did not requireyou to put much thought into it Dont blow off porphyria and leadpoisoning-- for some reason I got so many questions on that

Molecular Bio This was a big one lots of questions about DNAregulation transcription translation bacterial plasmids etc Sometimesthese questions look very scary -- they are always so long and use longnames for molecules or restriction enzymes that you have never heardof You need to get used to the question style and realize that whatthey are asking is very simple The NBME forms have questions verysimilar to the molecular bio ones I saw on the exam

Pharm Another one I thought would be difficult but not Big drugs youshould know a lot about (like antihypertensives drugs forhyperlipidemias cardic drugs etc) know side effects -- especially thechemo and immunosupressant drugs that kept on tripping me up somuch

MicroImmuno mostly bacterial processes and what you would use totreat them or what was their mechanism of disease (ie endotoxnexotoxin etc) Know immunology and cytokines well as well as thefunctions of all the cells Different immune deficiencies were all askedon my exam (there is one page in First Aid that sums them up verywell)

AnatomyNeuroanatomy Always combined with a pathology question oran imagine I had a few branchial plexuslumbar plexus questionsMany questions would give you a clinical scenario then ask you toidentiy the arterynerveorgan on a CT scanMRIangiogrambrain crosssection

Physio This was almost always combined with Pathology--they wouldask the physiology behind some path process I had so many questionswhere the question asked what would be the levels of x y and zenzymeshormones answer choices being increased decreased etc

Pathology lot of images -- MANY more than Qbanks representation

images from NBME test were repeated on my actual exam

Goljans book and lectures were great He pointed out lots of thingsthat wound up being on the exam and presents them in a way thatreally sticks Also his images are a great resource

as i already gave 1 qs which i heard from 1 of my frnd the qs is a female birth a baby who died soon after birth and her placenta wasedematous she has another child who goes to day carewat is thediagnosis of the child death1 ebv2 cmv3 parvovirusans is parvovirus

MLC - Most likely causeMLO - Most likely outome MLM - Most likely mechanismAE - adverse effect

MLM Cytochalasin D - actin polymerization diaphragm innervationtheophylline MOAVincristine MOACyclophosphamide - AEPotters syndrome - emb connectionSarcoidosis - hypercalcemia MLMADH MOAMLO paraxial mesoderm

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Paraneoplastic syn - SqCC AssociationMM - electrophoresis band patternApoptosis - blot picWNT 11 gene - nephro developmentRetinoic Acid - MOAgp 120abciximab AEOpen Angle glaucoma - RxBells palsy ML cause from a list of 10 or soIsoasthenuria MLCSpousal abuse next stepHS - AD disease - inheritance pattern from pedigreeMetanephrine VMA are metabolites in Nblastoma and Pheochromo -how would you differentiateBlunt trauma - damage to speenCT scan - medial meniscus - locateX ray skull - pit fossa - Sheehan syndromeACTH control over AC layersperoxidase - thyroid - HMP shunt connectionCarbamoyl Phos contribution to NT structureDavenport diagram - R-AlkalosisAs - Sq cell ca connectionzona pellucida glycoproteins

here is some stuff which i got just now1 anaphylaxis reaction in a ptgave epinephrine so wat mao of epi isans beta 2 effect2 placebo amp safety in which phase ans phase 13 turner synd pt has ammenorhea but she treted with estrogenprogesterone therapyto have regular menseturationshe want to bepregnant what possibility she haveans ova donation4 dantrolene moa 5 12 yr boy smooking cigratte and also steel mothers cigratte she isconcered abt itwat ans of a doca he send mom pap fprsmookingtherapyb he tells boy abt lung ca c give boy busprinone5 a pt have hypersensitivity bleeding easy brusing wat next complictionshe have ans was utrine rupture6 a pt have tetis and vagina a 5alpha redutase def Bdihydrotestosterone defc receptor respond ans c7 predisposition ovarian ca8 a female brt grand pa to doc he had alziemerswhen doc chek hefound stages of healing ans was elder abuse9 which heart diesease in turner10 64 yr old male bone pain lytic lesion ans multiple fracture11 a 16 yr old grl bt inc pt incwhich factor absent ans 812 moa of cholestyramine13 in copd contraindicated drug is proparanol14 asthma frst line of tretment15 2 qs abt dilated cardiomyopathy16 5 qs abt b12 def17 moa cisplatin18 a women homeless live near by pesticide comp he sensoryinnervation goneand has stocking glove pattern skin infectionwat is thecoz a lead poisioning b leprosy ans is b19 a pt whose daughter took him to er tell abt she found near herfather bed theophyline bottle codine albuterolthr is some more historywat treatment shld antidote naloxaone

Q) on how would you differentiate bt Klebsiella from Salmonella ALactose fermentation

Q) about Lesch Nyhan Syndrome- What Accumulates A uric acid

Q)drug of choice for increased VLDL A Niacin

Q) asks about what part of the Antibody binds to cells A FC portion

Q) describes a child with eczema low platelets and immune def- askdiagnosis A Wiscott Aldrich Syndrome

Dx of herpes vesicular painful lesions2 Conversion disorder saying pt paralyzed on one side3 Schizotypal DO pt lives with a lot of cats and is happy by herself4 Sublimation defense mechanism burned victum goes out for fund

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raising5 Arteriogram of ACA pt with lower exteremity paralysis6 MRI of spine shown pt cant feel pain and temp on lowerexteremites7 Esophageal veins initiates from what vein8 Gag reflex9 Thymus anatomical location between manubrium and hyoid bone10 1st part of doudinum fed by what artery11 loss of dorsiflexion what nerve12 what artery supplies testicles where does it comes from13 what nerve supplies anal area14 Histologic pic shown Dx Diabetic GN15 IgA def pulmonary problems Dx16 Described skin infection DXHZV17 Arrest of ovum prophase I18 40 yo undecended testes his spermatogonia is in what phasehaploid diploid n 2n19 Odd ratio just simply know the formula20 Beta error 1-B 90 (dont recall the whole thing

21 Case control study retrospective22 Describe specifity23 eyes can not do lateral gase but looking down and up is ok Whatnerve damaged24 pt can not look medially what nerve damaged25 Renal cell carcinomavit D26 Thyroxine T4 activates what receptor eg thyrosine kinase27 Steroid receptors28 PDAcyanosiscontinious murmur at the ApexgtL hrthyperthpy29 Older pt calcification of valves vegitation30 Heme synthesis option was Succinyl CoA

PX with signs amp symptoms of goodpasture what would lm show onbiopsycresentphoto of plasma cella pt with lytic lesion vertebra wat diseasewat drug usually given pretreatment for leukemiamoa of doxurubicinmoa abacavir(ans reverse transcriptase inhibitor)ho pt having gynecomastia labast alt incans ketoconazola Diag exactlly 4m frst aid ans chancrestaright qs abt BPHASKING qs abt endometriosispedigree of mito inheritancecleft lip failure of watcase of alcholic hepatitisho UMN lesion identify the lesion MRICASE SENSITIVITY AND SPECIFICITYpt having wt lose some psychtic symptom dilated pupil asking abt drugabuset

31 Rate limiting step in heme synthesisacirceurobrvbarALA32 steatoureaacirceurobrvbarbc of HMG-CoA reductase33 what is increased in lack of HMG-CoA reductaseTriglycerides Chylomicrons34 pt Macrocytic neurological defacirceurobrvbargtB12 def35 pt with gastritis fundus region anti-bodyagainst IFacirceurobrvbarwhat will be deficient36 B12 def acirceurobrvbarterminal illium37 Described Chronacirceurotrades dizacirceurobrvbarasked lesions are whereJujunium with bloody diarrhea38 Rhumatiod arthritis39 Pic of swallen finger Septic arthritis40 pic of small petichia on skinacirceurobrvbarwhat is def vit Cdef

PT in hot sun gets red on her faceacirceurobrvbarbc of Options Melanocytes-ADA deficient what cumulates Options Adenineuric acid urea- MOA Colchicine- pt has low O2 satacirceurobrvbar 75 bc of options 23BPG

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decreasedacirceurobrvbar- acirceurotrades given DM1 ketoacidosis MetabolicAlkolysis and acidosis- post-op 7 days MRI shownacirceurobrvbaroption PE- UTI older pt no Ecoli in the optionsacirceurobrvbarbut G-diplocco- Picnic meat watery diaacirceurobrvbarwhat bug Optionscamplobacter juju strep saphraticus c basillus - Pt With bloody diarrhea what bug - umbilical vein or artery thrombus to wherecauses cerebral infarct why Options open foramensecondum- VQ mismatch options perfusion decreased atapex or higher O2

acirceurobrvbarKNOW ENDOCRINE PHYSIOLOGY AND PATHOPHYSIOLOGY acirceurobrvbaracirceurobrvbar Know your vitamins very wellImmuno-know all the cytokines neuro - know the cerebral cortex very wellall the areas-brocaswernickes etcmany questions on spinal cord segmentsmost of the neuro questionswere based on imagesa nurse use iodine before giving insulin why--to sterlize that areafrom virusbacteria and fungi a girl has 28 days cyclephyscian do her hormone teston the day26 what hormone will be increase ---option are FSHLHTSHHCG MAKE SURE HOW TO READ CT SCANS AND MRIS THE ANATOMYQUESTIONS HAD ALOT OF CT SCANS SHOWING VARIOUS MUSCLESLike for example some person had a superior gluteal nerve lesion andit had a CT scan of the pelvis and you had to identify the MUSCLEAlso 2 QUESTIONS ON EPIDURAL HEMATOMA ASKED WHICH ARTERYIS DAMAGED FETAL ALCOHOL SYNDROME KNOW THE SIGNS (DONT GETCONFUSED WITH DOWNS SYNDROME)HYPERHYPO THYROIDISM

1)Pituitary tumor on visual fields PITUTARY TUMOUR ISCRANIOPHRANGIOMA CAUSES BITEMPORAL HEMIANOPSIA

2)Tumor anterior to temporal fossa affects wot 3)Tends to fall to one side tongue deviates to othersite of lesion THIS is problem in 12 cranial nerve which is locted inlower medulla4)Pediatric infratentorial tumor most of the paediatric tumours areinfra tentorialthey are celleblarastrocytoma2medulloblastoma3gliomas

5)Midline neck mass at level of hyoid BRANCHIAL CYST

6)Esophagal hiatus of diaphragm IT OPENS AT THE LEVEL OF T10 IVChiatus at T8descending aorta opening at T12

7)Splenic venous drainage VENOUS SINUSOIDS IN CORDS OFBILROTH8)Ambiguous genitalia AMBIGOUS GENITIAL is in female with excessof testosterone or in male with lack of testorone

9)Melanosis coli MELONOSIS COLI I is due over use of laxativescolonappers black in colour Melanosis coli is due to use of laxatives notantibiotics Usually anthraquinone ( senna and cascara)10)Inhalational antigen stimulation leading to antibodyrecovery from vaginal mucosa of experimental animalHow It is called Dissemination of Immunologic Memory and it is thesame mechanism used in Adenovirus Vaccine The adenovirus vaccine used by the military against adenovirus types 4and 7 is an enteric-coated live non-attenuated virus preparation This vaccine produces an asymptomatic intestinal infection and therebyinduces mucosal IgA memory cells These cells then populate the mucosal immune system throughout thebody ( Because Memory cells tend to home in a tissue-specific fashion presumably returning to the type of tissue in which they first

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encountered antigen)Vaccine recipients are thus protected against adenovirus acquired byaerosol which could otherwise produce pneumonia

11)x-ray foot with calcification parallel to firstmetatarsal with decreased dorsalis pedis myositis ossificens12)Ligament that holds tibia from goin back ant and posterior cruciateligments--- that holds tibia from going back is Posterior crusiate ligament -----ligament that prevents tibia from coming forward is Anterior cruciateligament13)Obturator nerve section effects obtutaror nerve injury leads to lossof adduction of thigh14)Pelvic ascites site of drainage on standing position the site ofdrainage is vescicouteric pouch in females and rectovescical poch inmales15)Aortic aneurysm rupture effect on urinalysis in thebackground of anuria aortic aneurysm leads to renal infarctionso therewill rbc in urine16)Hand decreased sensation lateral aspect median nerve injury17)Hand sensation ok but extention ofmetacarpophalangeal joints difficult exention and flexion are done bylumbricals and interossis muscles the extension at MP joint by---gtextensors of the fingersflexion at MP joint by---gtlumbricals and introssei so if extension isdifficult means extensors are weakwhich are supplied by radialnerve

18)Clubbing description choices bronchiectasis asthma clubbing isseen in bronchiectasis

Q1) Cystic fibrosis heterozygous frequency Q2) Chemotherapy heart failure acirceuroldquo left heartrightheartmyocardial fibrosis Maybe Doxorubicin (Adriamycin) FA p330 orDaunorubicin But have no idea what is the mechanismQ3) Stimulants and inhibitors of pancreatic secretionsexocrine and endocrine Exocrine- Stimulants CCK Secretin parasympathetics Inhibitors None Endocrine- Insulin Stimulants Glucose Amino Acid GIP Glucagon Insulin Inhibitors Somatostatin Sympathetics (Alpha) Glucagon Stimulants Amino acid Glucagon Inhibitors Insulin Somatostatin

Q4) Cellular barrier between gall bladder cavity andwallacirceurotrades epithelial cells is maybe asking for Tight junction Tightjunction must be there to protect the internal celluar structures fromnasty bileQ5) Embryology neural tube formation cellular dnafragmentation indicates Apoptosis Q6) War veteran describing killing business like acirceuroldquo defence mech

Q7) Trigeminal nerve nucleus identification in medulla ct cross section(you can just say verbally where its located) Q8) Efferent renal constriction effects on GFR ampFiltration fraction GFR amp FF both increasesQ9)Premature birth surfactant and steroid therapy fails due to surfacetension increasedecrease etc Q10) Barret esophageal cancer type Adenocarcinoma since barrettsis Metaplasia full of intesinal cellsQ11)GERD cuz of secretions from which type of gastric cells BRS Physiology(p223) says that the relaxaton of loweresophageal sphincter is vagally mediated and the neurotransmitter isVIP Or maybe GERD could be due to gastric acid therefore parietal cellcould be an answerQ12) Cholecystectomy patients absorb fat from Cholecystectomy ptwill still absorbing fat from terminal ileum I think well ofcourse fromsmall intestine cholecystectomy has nothing to do with the site ofabsorbtion the person still produces bile( in liver) just no storage or conecentrationof bile thats why post op cholecystectomy patients are put on low fatdiet

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but site of absorbtion remains small intestine (ileum) as usual

Q13)Sputum silver staining for bugs silver staining reminds me of twobugsbut I am not sure Pneumocysyis carinii Legionella pneumoniaeBut silver staining of PCP is done on pts Bronchoalveolar lavage IguessQ14) First thing to say to dad patient brought by 2daughters who express wish to remain with patientBest statement to make to build rapport with patientplaying crossword on encounter May be Doctor have to ask the ptwhether he wants their daughter in the room while interviewingQ15) Post break-up with boyfriend mother of patient finds synthroidtablets in nursing student daughteracirceurotrades belongings Docacirceurotrades responseto patient synthyroid is Thyroid hormone I guess but not sure if it isT3 or T4 the pt may be planning on weight loss because boyfriendhated her obesity q16)Fragile X family parents concern regarding testing of normal 14-year daughteracirceurotrades genome for similar problems Q 17) Girl child dumps classes since uncleacirceurotrades death and mother findsit helpful for daughter to be around home Intervention requiredFamily therapypsychotherapyacirceurobrvbaretc Q18) Porphyrias like the back of ur hands q19) Carbon tetrachloride how it affects liver CCl4 - The liver convertsCCl4 to a CCl3 free radical which damages the liver (fulminanthepatitis fatty change) from Goljans STARS pathology review p93

Acyclovir mechanism of action inhibhits DNA viral poymerase andphosphorylated by viral thymidine kinaseQ20) Hernia above n lateral to pubis Hernia above the inguinal lig isInguinal hernia and below the lig is femoral hernia So it could beboth Indirect and direct inguinal hernia since it doesnt say anythingabout hernias relation to inf epigastric vesselsQ21)Hydatidiform mole learn how to interpret genotypes of moles

Which 2 Joints are Never affected in RA Distal interphalangeal and theBack joints r never involved in RAQ1) Best means of bringing down temperature of seizingpatient with meningitis pharmacologic and otherwise think nonpharamacologic tt shd be hydrotherapy to bring down tempnpharamacologic may be paracetamol by rectal routeQ2) Acetaminophen overdose how it damages In overdose the storesof GSH are depleted and and the metabolite N-acetylbenzoquinoneiminereacts with hepatocytes leading to liver necrosis Acetaminophen formsfree radicals in the liver and results in fulminant hepatitis renalpapillary necrosisdamages by free radicals which r removed by glutathioneNACETYLCYSTEIN its antidote restores the glutathione levelsQ3) Antimicrosomal antibodies involved in hashimotos autoimmunethyroiditis and autoimmune hepatitisQ4)Dialysis patient on transplant list gets angry often and missesdialysis appointments - intervention need to spend more time withpatientdiscuss regardingreconsideration of transplant listacirceurobrvbaretc Dialysis patient on transplantlist gets angry often and misses dialysis appointments - interventionneed to spend more time with patientdiscuss regarding reconsiderationof transplant listacirceurobrvbaretc need to spend more time with patient toknow what exactly is his probQ5) Adenovirus acirceuroldquo structure nonenvelopedds linear DNA icosahedralnucleocapsid only virus with a fibre protruding from each of 12 verticesof teh capsidQ6) Brown fat of neonates Function site of heat production in aneonate---brown adipose tissue contain natural uncoupling proteinwhich allows energy loss in the form of heat to maintain basal tempQ7) Longterm steroid use effect on adrenals adrenal suppressiontherefore tapered slowly neg feed back on ant pit so decreased ACTHso less stim of adrenalsacirceurobrvbarhypothalamo pituitary axis and eventuallyleads to atrophy of the adrenal glandQ8) Trypanosome cruzi life cycle try cruzi lifecycle involves reduvidbud as a vector and both humans and animals as reservoirs life cycleacirceurobrvbar reservoirs are cats dogsacirceurobrvbar reduviid bug passes the trypomastigoteas it bites and scratching implants in bite siteacirceurobrvbaracirceurobrvbaracirceurobrvbarreservoir isrodents armadillos vector is reduviid bug it transmits the trypo-mastigote form which turns into the amastigote form inside the body Atthe bite site the lseion is called chagoma Systemic symptoms are

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fever lymphadenopathy Tachycardia meningoencephalitis Thencomes the intermediate phase where the patient is asymptomatic withlow levels of the parasite and antibodies against it decades later-thechronic form emerges with dilated cardiomyopathy megacolonmegaesophagusTreatment is NifurtimoxQ9)Patient requiring dialysis says donacirceurotradet want machines to keep mealive Docacirceurotrades next step Q10)Antifungals big time Drug interactions Mechanism of actions(letswrite few antifungals with mech of action and main side effectswe willnever forget it if we do so) amphotericin B binds ergosterol creates poresflucytosine-inhibit thymidilate synthaseazole-inhibit ergosterol synthesisgriesofulvin-interfere with microtubule functionterbinafine- inhibit squalene epoxideDRUG INERACTIONSAZOLE GRP INCREASE TOXICITY OF FOLL BY INHIBITING ITSMETABOLISMbdzcisapridecyclosporinefluoxetinelovastatinomeprazoleQ11) Alcoholic with nosebleed Wot to expect in terms of AST PT andforgotacirceurobrvbar( I dont know exactly whats being askedlets see who figuresit out) AST is increased platelet count is decreased prolonged PTQ12)Picture of normal hand and a slender hand shown and asked fordiagnosis Q13)Wernicke mammillary body identification on CT( here just name thestructures affected in wernickes encephalopathy and ofcourse do knowhow to identify themvery very HY) mammillary bodies anddorsomedial nucleus of thalamusacirceurobrvbarMamillary bodies on the ventralsurface of the brain stemQ14) How HBV causes liver cancer HBV DNA integrates in hostgenomic DNAMODIFICATIONOF GENE EXPRESSION HBVINCORPORATES itself into the hepatocyte dna and triggers malignantgrowth theres is a 200 X Risk of developing HCC in carriers versusnoncarriersQ15)Patient taking OCP Smoker Wot u wanna check first smokinginduces met enzymes increased metabolism of OCPSdecreased efficacySmoking itself is thrombogenic and estrogen also isacirceurobrvbar ask for historyof thrombosis may be check PT PTTQ16)Allopurinol acirceuroldquo effect on renal stones It inhibits xanthine oxidasedecreasing uric acidallopurinol used in pts of renal stones as calcium oxalate stone formersare hyperuricemicQ17)Radiation alopecia acirceuroldquo dermal histopathology sparse mixeddermal inflammatory infiltrate consisting mainly of lymphocytes Mucinous deposits confirmed by alcian bluePAS stain were observedwithin the epidermis of the hair follicleQ18)Streptococcus pyogenes acirceuroldquo patient penicillin allergicNext step Can give Clavulanic acid Sulbactam TazobactamCephalosporins should be avoided in patients allergic to penicillinbecause of cross sensitivity Cephalosporins are susceptible to betalactamase but less than penicillin penicillin allergic pts erythromycinor azithromycin are the alternatives all GRP A Streptoccoci r susceptibleto pencillin G but neither Rhematic fever nor allergic pats benefit frompencillin treatment after onset In pencillin allergies pats should geterythromycin or azithromycinHOWEVER ENTEROCOCCAL ENDOCARDITIS CAN BE ERADICATED ONLYBY PENICILLIN OR VANCOMYCIN COMBINED WITH ANAMINOGLYCOSIDEQ19)t-Rna triplet codon function The anti codon on the tRNA pairs withthe codon for aa in mRNA Q20) Nuclear membrane acirceuroldquo evolutionary importance betweeneukaryotes and prokaryotes all I know is nucleus membrane is absentin prokaryotes and present in euk may be evolutionary imp is to protectthe genetic information

there are 4 trigeminal nuclei---gt1)primary sensory nuclei for sensations of face2)spinal trigeminal nucleus for pain and tempreature sensation of face3)Mesencepahalic nucleus for proprioception4)primary motor nucleus for muscles of mastication

ZEBRA genesZ EBV replication activator (ZEBRA) as lytic cycle

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markersZEBRA is one of the immediate early genes of EBVit isconsidered to be expressed in the initial stage of the lytic cycle beforethe viral particles have been dispersed Zebra sign Hemorrhage is often characterized by a typical streakybleeding pattern due to blood spreading in the cerebellar sulci thiszebra-pattern hemorrhage seems to be typical in a postoperative lossof CSF Zebra bodies - lipid inclusions with concentric lamellar structure withalternating light and dark-staining bands in neuronal cells in neimannpicks Zebra tumor = acoustic neuromaQ1)Lead poisoning( symptoms) --Lead poisoningacirceurobrvbar lead inhibitsferrochelatase and ALA dehydraseacirceurobrvbar coproporhyrin and ALAaccumulate in urine sympacirceurordquoabdominal colic sideroblastic anemiawrist and foot drop lead lines in gingivae and epiphysis of long bonesencephalopathy basophilic stipplingQ2) Glutamine in urea cycle Q3) Large intestine gross section tumor shown Type(felt like the napkin constriction)I never heard of this kind oftumoranyone knows Q4) Radiation therapy pelvis Cause for urinary retention cystitsfibrosisQ5) Osteogenesis imperfecta defect d AD mutation in collagen genesQ6) Medial side of arm numbness after mastectomy nerve involvedintercostobrachial n also known as the lateral cutaneous br of theventral primary ramus of T2Q7) Interleukins big time Learn function of eachwe can namesomeand functionIL1- stim produced mainly by macrophages IL2 syn pyrogenic activates TH IL2- downreg TH2 Tcell growthfactor stim BcellIL3- stim BM stem cellsIL4-class switch to IgEIL5-Class swish to eosinophil promote B cell prolifIL6- produc of acute phase reactantsIL8-chemotactic and adhesion of neutrophilsIL10-Inhibit TH1 inhibit cytokine from macrophageIL12-induce TH0 to TH1Q8) Plummer Vinson esophageal defect Esophageal websacirceurobrvbar irondeficiency anemia o Stomatitis o Glossitis o Dysphagia o Spoon-shaped nails o Esophageal webs

Q9)Scurvy enzymereaction involved Prolyl and lysyl hydroxylase theenzymes that catalyzes the hydroxylation require vitamin CQ10)Reiter syndrome vs Sjogren Reiter syndrome--- urethritis conjunctivitis and ant uveitis arthritisSjogrenXerophthalmia xerostomia arthritis parotid enlargementQ11)Managing hypertensive crisis in MAO inhibitor patient on cheeseitacirceurotrades pathogenesis Treatment ot a Hypertensive Crisis from MAOIReactionThis is a medical emergency with cerebral vascular accidents being oneof the greatest concerns Medical consultation is warranted Patientsshould report to an immediately to an emergency department Initialtreatment options include Phentolamine 5 mg IV or Thorazine 50 to 100 mg po Care should be taken to ensure that the patient does not becomedangerously hypotensive or that the hypertensive state returns once theintervention medication has worn off Tyramine is actively transportedinto neurons and displaces NE leading to intraneuronal release of NEIt can be degraded by MAO but if you are on MAOI its interaction willcause tyramine build up Tons of NE will be replaced and hence theHTN crisisQ12) Neurotransmitter involved in Huntington Decreased GABA andAChQ13)Aortic coarctation site of constriction and symptoms infantile typeis preductal Cardiomegaly Pulmonary venous congestion RightVentricular HypertrophyAdult is postductal asso with notching of ribs Displaced esophagealshadow rightward Left Ventricular Hypertrophy HT in UL weak pulsesin LL

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Q14) Chronic antiplatelet drug in aspirin sensitive Clopidogrel ampTiclopidine They are back-up or alternative drugs to aspirin Theyblock ADP receptors on platelets hence decrease activationQ15)Stroke patient getting MI treated with streptokinasedies due to cva Cause concluded that death of the patient occurreddue to rebleeding on administration of streptokinase 1 IntracranialHemorrhage As PRS has mentioned the death could be due to intracranialhemorrhage Since CVA refers to both ischemic (80) andhemorrhagic(20)This is more likely than other explanation to me

2 Therapeutic Failure It could be due to strptokinases property itselfSince most individuals have had a streptococcal infection sometime intheir lives circulating antibodies against streptokinase are likely to bepresent in most patients These antibodies can combine withstreptokinase and neutralize its fibrinolytic properties (Therapeuticfailure)(lippincott Pharmacology 2nd edition p203) 3 Property of all Thrombolytic agents As the thrombolytic agents dissolute clot Increased local thrombinmay occur as the clot dissolves leading to enhanced plateletaggregability and thrombosis Strategies to prevent this includeadministration of antiplatelet drugs such as aspirin orantithrombotics such as heparin

Drugs that have been implicated in the development of serum sickness-like reactions include the following allopurinol (Zyloprim) arsenicalsand mercurial derivatives barbiturates captopril (Capoten)cephalosporins furazolidone (Furoxone) gold salts griseofulvin(Fulvicin Grifulvin) halothane hydralazine (Apresoline) iodidesmethyldopa para-aminosalicylic acid penicillamine penicillinsphenytoin (Dilantin) piperazine procainamide (Procan SR ProcanbidPronestyl-SR) quinidine (Quinaglute Quinalan Quinidex Quinora)streptokinase (Streptase Kabikinase) sulfonamides and thiouracils

Q16)Leukotriene inhibitors ZafirlukastacirceurobrvbarLT receptor antagonistQ17) Chromolyn sodium Mechanism of action prevent degranulation ofmast cellsQ18)Graveacirceurotrades pathophysiology autoimmune TSH receptor antibodiestype II hypersensitivityQ19) Couple in for infertility counseling High BMI Wifesays acirceuroœit kills me not to be able to have a babyacirceuroDocacirceurotrades best response obese wife possibly has Polycystic OvarianSyndrome (PCOS)74 of PCOS pt has infertility and PCOS accounts for 30 of overallinfertilityTherefore the doctor may have to evaluate for PCOS by Lab bloodtest and Ultrasonography The lab blood test will show Increasedandrogen LH fasting insulin prolactin and estrogens Theultrasonography is the most sensitive diagnostic study If the Dx of PCOS have been confirmed Tx should be Weightreduction quit smoking and antiandrogen(because of hirsutism) andantiestrogen(clomiphen)

Q20)Baby awakens at night frightened goes back to sleepDoes not respond to questions b parents on that awakening Best nextstep The boy is possibly having Night Terrors It occurs in Delta sleep so you cant wake them and they cant remember what happened Andnight terror is shown to be precursor to temporal lobe epilepsyThe doctors response should be either examine for any epilepsy in the pt(prevent or tx the temporal lobeepilepsy) or Identify amp dealing with waking-time anxiety to relieve night terrorsceliac disease is the proximal bowel and tropical sprue involves the entire bowel

Q1) Prematue ejaculation Best next step Ans- selective seratononreuptake inhibhitors like fluoxetine or even clorpramine (which is themost seratonin specific hetrocyclics)Q2)Delirium big time ( just define) Ans-Impaired conciousness(incontrast to dementia which is loss of

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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9- A boy has deficiency of skull mineralization what is affected afibrillin b chondroiin c collagen d heparin sulfate

10- A pt has kidney stones how do you treat him a mannitol bfurosemide c spironolactone d hydrochlorothiazide e indapamide11- Not clear12- Not clear13- MRI of brain with a mass in the ventricle this tumor most probablyfrom a melanocyte b epithelial cells c meningioma14- Q about apoptosis

15- A labeled draw of virus infecting a cell asked about which level dothe nucleoside RT inhibitors affect16- A pt had heart transplant and now is treated with cyclosporinethen he got respiratory problem with decreased lung functions what isthe cause a CMV b PCP17- A pt has cardiac tamponade what do you see under microscopeafter two hours prove that itacirceurotrades irreversible injury A acute swellingof mitochondria b acute swelling of plasma membrane c migration ofnucleus18- What is the most important factor for otitis externa APaeurginosa b S pneumoniae19- A female with STD she has microorganism covering skin cells andclue cells what is the diagnosis A candida b trichomonas c bacterialvaginosis20- Two girls 16 and 14 years old came to you the 14 years girl hasSTD what is your next step A treat her with permission of her oldersister b treat her without permission c treat her with her parentspermission21- A pt with cancer in need to surgery but his response is that acirceuroœwhat is the benefit if Iacirceurotradem gonna die soonacirceuro your response is Aask him to go and get help b show him cases with the same disease sohe can agree for surgery

11- Not clear12- Not clear13- MRI of brain with a mass in the ventricle this tumor most probablyfrom a melanocyte b epithelial cells c meningioma14- Q about apoptosis

15- A labeled draw of virus infecting a cell asked about which level dothe nucleoside RT inhibitors affect16- A pt had heart transplant and now is treated with cyclosporinethen he got respiratory problem with decreased lung functions what isthe cause a CMV b PCP17- A pt has cardiac tamponade what do you see under microscopeafter two hours prove that itacirceurotrades irreversible injury A acute swellingof mitochondria b acute swelling of plasma membrane c migration ofnucleus18- What is the most important factor for otitis externa APaeurginosa b S pneumoniae19- A female with STD she has microorganism covering skin cells andclue cells what is the diagnosis A candida b trichomonas c bacterialvaginosis20- Two girls 16 and 14 years old came to you the 14 years girl hasSTD what is your next step A treat her with permission of her oldersister b treat her without permission c treat her with her parentspermission21- A pt with cancer in need to surgery but his response is that acirceuroœwhat is the benefit if Iacirceurotradem gonna die soonacirceuro your response is Aask him to go and get help b show him cases with the same disease sohe can agree for surgery

Viruses that carry virion associated polymerase what is the enzyme thatis not found inthe cytoplasm and this enzyme is used instead a DNA dependant DNApolymerase b DNAdependant RNA polymerase c RNA dependant RNA polymerase

Re2007 Crush Bank 653475 ericvorheese - 020907 1935

Remembered questions for STEP 1 - USMLE Forum

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great idea heres my contributionan experience from a test thatwas taken earlier this week -

Biochem some key enzyme deficiency ones (Lesch Nyhan Maple SyrupDisease) but all of the questions were very obvious and did not requireyou to put much thought into it Dont blow off porphyria and leadpoisoning-- for some reason I got so many questions on that

Molecular Bio This was a big one lots of questions about DNAregulation transcription translation bacterial plasmids etc Sometimesthese questions look very scary -- they are always so long and use longnames for molecules or restriction enzymes that you have never heardof You need to get used to the question style and realize that whatthey are asking is very simple The NBME forms have questions verysimilar to the molecular bio ones I saw on the exam

Pharm Another one I thought would be difficult but not Big drugs youshould know a lot about (like antihypertensives drugs forhyperlipidemias cardic drugs etc) know side effects -- especially thechemo and immunosupressant drugs that kept on tripping me up somuch

MicroImmuno mostly bacterial processes and what you would use totreat them or what was their mechanism of disease (ie endotoxnexotoxin etc) Know immunology and cytokines well as well as thefunctions of all the cells Different immune deficiencies were all askedon my exam (there is one page in First Aid that sums them up verywell)

AnatomyNeuroanatomy Always combined with a pathology question oran imagine I had a few branchial plexuslumbar plexus questionsMany questions would give you a clinical scenario then ask you toidentiy the arterynerveorgan on a CT scanMRIangiogrambrain crosssection

Physio This was almost always combined with Pathology--they wouldask the physiology behind some path process I had so many questionswhere the question asked what would be the levels of x y and zenzymeshormones answer choices being increased decreased etc

Pathology lot of images -- MANY more than Qbanks representation

images from NBME test were repeated on my actual exam

Goljans book and lectures were great He pointed out lots of thingsthat wound up being on the exam and presents them in a way thatreally sticks Also his images are a great resource

as i already gave 1 qs which i heard from 1 of my frnd the qs is a female birth a baby who died soon after birth and her placenta wasedematous she has another child who goes to day carewat is thediagnosis of the child death1 ebv2 cmv3 parvovirusans is parvovirus

MLC - Most likely causeMLO - Most likely outome MLM - Most likely mechanismAE - adverse effect

MLM Cytochalasin D - actin polymerization diaphragm innervationtheophylline MOAVincristine MOACyclophosphamide - AEPotters syndrome - emb connectionSarcoidosis - hypercalcemia MLMADH MOAMLO paraxial mesoderm

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Paraneoplastic syn - SqCC AssociationMM - electrophoresis band patternApoptosis - blot picWNT 11 gene - nephro developmentRetinoic Acid - MOAgp 120abciximab AEOpen Angle glaucoma - RxBells palsy ML cause from a list of 10 or soIsoasthenuria MLCSpousal abuse next stepHS - AD disease - inheritance pattern from pedigreeMetanephrine VMA are metabolites in Nblastoma and Pheochromo -how would you differentiateBlunt trauma - damage to speenCT scan - medial meniscus - locateX ray skull - pit fossa - Sheehan syndromeACTH control over AC layersperoxidase - thyroid - HMP shunt connectionCarbamoyl Phos contribution to NT structureDavenport diagram - R-AlkalosisAs - Sq cell ca connectionzona pellucida glycoproteins

here is some stuff which i got just now1 anaphylaxis reaction in a ptgave epinephrine so wat mao of epi isans beta 2 effect2 placebo amp safety in which phase ans phase 13 turner synd pt has ammenorhea but she treted with estrogenprogesterone therapyto have regular menseturationshe want to bepregnant what possibility she haveans ova donation4 dantrolene moa 5 12 yr boy smooking cigratte and also steel mothers cigratte she isconcered abt itwat ans of a doca he send mom pap fprsmookingtherapyb he tells boy abt lung ca c give boy busprinone5 a pt have hypersensitivity bleeding easy brusing wat next complictionshe have ans was utrine rupture6 a pt have tetis and vagina a 5alpha redutase def Bdihydrotestosterone defc receptor respond ans c7 predisposition ovarian ca8 a female brt grand pa to doc he had alziemerswhen doc chek hefound stages of healing ans was elder abuse9 which heart diesease in turner10 64 yr old male bone pain lytic lesion ans multiple fracture11 a 16 yr old grl bt inc pt incwhich factor absent ans 812 moa of cholestyramine13 in copd contraindicated drug is proparanol14 asthma frst line of tretment15 2 qs abt dilated cardiomyopathy16 5 qs abt b12 def17 moa cisplatin18 a women homeless live near by pesticide comp he sensoryinnervation goneand has stocking glove pattern skin infectionwat is thecoz a lead poisioning b leprosy ans is b19 a pt whose daughter took him to er tell abt she found near herfather bed theophyline bottle codine albuterolthr is some more historywat treatment shld antidote naloxaone

Q) on how would you differentiate bt Klebsiella from Salmonella ALactose fermentation

Q) about Lesch Nyhan Syndrome- What Accumulates A uric acid

Q)drug of choice for increased VLDL A Niacin

Q) asks about what part of the Antibody binds to cells A FC portion

Q) describes a child with eczema low platelets and immune def- askdiagnosis A Wiscott Aldrich Syndrome

Dx of herpes vesicular painful lesions2 Conversion disorder saying pt paralyzed on one side3 Schizotypal DO pt lives with a lot of cats and is happy by herself4 Sublimation defense mechanism burned victum goes out for fund

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raising5 Arteriogram of ACA pt with lower exteremity paralysis6 MRI of spine shown pt cant feel pain and temp on lowerexteremites7 Esophageal veins initiates from what vein8 Gag reflex9 Thymus anatomical location between manubrium and hyoid bone10 1st part of doudinum fed by what artery11 loss of dorsiflexion what nerve12 what artery supplies testicles where does it comes from13 what nerve supplies anal area14 Histologic pic shown Dx Diabetic GN15 IgA def pulmonary problems Dx16 Described skin infection DXHZV17 Arrest of ovum prophase I18 40 yo undecended testes his spermatogonia is in what phasehaploid diploid n 2n19 Odd ratio just simply know the formula20 Beta error 1-B 90 (dont recall the whole thing

21 Case control study retrospective22 Describe specifity23 eyes can not do lateral gase but looking down and up is ok Whatnerve damaged24 pt can not look medially what nerve damaged25 Renal cell carcinomavit D26 Thyroxine T4 activates what receptor eg thyrosine kinase27 Steroid receptors28 PDAcyanosiscontinious murmur at the ApexgtL hrthyperthpy29 Older pt calcification of valves vegitation30 Heme synthesis option was Succinyl CoA

PX with signs amp symptoms of goodpasture what would lm show onbiopsycresentphoto of plasma cella pt with lytic lesion vertebra wat diseasewat drug usually given pretreatment for leukemiamoa of doxurubicinmoa abacavir(ans reverse transcriptase inhibitor)ho pt having gynecomastia labast alt incans ketoconazola Diag exactlly 4m frst aid ans chancrestaright qs abt BPHASKING qs abt endometriosispedigree of mito inheritancecleft lip failure of watcase of alcholic hepatitisho UMN lesion identify the lesion MRICASE SENSITIVITY AND SPECIFICITYpt having wt lose some psychtic symptom dilated pupil asking abt drugabuset

31 Rate limiting step in heme synthesisacirceurobrvbarALA32 steatoureaacirceurobrvbarbc of HMG-CoA reductase33 what is increased in lack of HMG-CoA reductaseTriglycerides Chylomicrons34 pt Macrocytic neurological defacirceurobrvbargtB12 def35 pt with gastritis fundus region anti-bodyagainst IFacirceurobrvbarwhat will be deficient36 B12 def acirceurobrvbarterminal illium37 Described Chronacirceurotrades dizacirceurobrvbarasked lesions are whereJujunium with bloody diarrhea38 Rhumatiod arthritis39 Pic of swallen finger Septic arthritis40 pic of small petichia on skinacirceurobrvbarwhat is def vit Cdef

PT in hot sun gets red on her faceacirceurobrvbarbc of Options Melanocytes-ADA deficient what cumulates Options Adenineuric acid urea- MOA Colchicine- pt has low O2 satacirceurobrvbar 75 bc of options 23BPG

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decreasedacirceurobrvbar- acirceurotrades given DM1 ketoacidosis MetabolicAlkolysis and acidosis- post-op 7 days MRI shownacirceurobrvbaroption PE- UTI older pt no Ecoli in the optionsacirceurobrvbarbut G-diplocco- Picnic meat watery diaacirceurobrvbarwhat bug Optionscamplobacter juju strep saphraticus c basillus - Pt With bloody diarrhea what bug - umbilical vein or artery thrombus to wherecauses cerebral infarct why Options open foramensecondum- VQ mismatch options perfusion decreased atapex or higher O2

acirceurobrvbarKNOW ENDOCRINE PHYSIOLOGY AND PATHOPHYSIOLOGY acirceurobrvbaracirceurobrvbar Know your vitamins very wellImmuno-know all the cytokines neuro - know the cerebral cortex very wellall the areas-brocaswernickes etcmany questions on spinal cord segmentsmost of the neuro questionswere based on imagesa nurse use iodine before giving insulin why--to sterlize that areafrom virusbacteria and fungi a girl has 28 days cyclephyscian do her hormone teston the day26 what hormone will be increase ---option are FSHLHTSHHCG MAKE SURE HOW TO READ CT SCANS AND MRIS THE ANATOMYQUESTIONS HAD ALOT OF CT SCANS SHOWING VARIOUS MUSCLESLike for example some person had a superior gluteal nerve lesion andit had a CT scan of the pelvis and you had to identify the MUSCLEAlso 2 QUESTIONS ON EPIDURAL HEMATOMA ASKED WHICH ARTERYIS DAMAGED FETAL ALCOHOL SYNDROME KNOW THE SIGNS (DONT GETCONFUSED WITH DOWNS SYNDROME)HYPERHYPO THYROIDISM

1)Pituitary tumor on visual fields PITUTARY TUMOUR ISCRANIOPHRANGIOMA CAUSES BITEMPORAL HEMIANOPSIA

2)Tumor anterior to temporal fossa affects wot 3)Tends to fall to one side tongue deviates to othersite of lesion THIS is problem in 12 cranial nerve which is locted inlower medulla4)Pediatric infratentorial tumor most of the paediatric tumours areinfra tentorialthey are celleblarastrocytoma2medulloblastoma3gliomas

5)Midline neck mass at level of hyoid BRANCHIAL CYST

6)Esophagal hiatus of diaphragm IT OPENS AT THE LEVEL OF T10 IVChiatus at T8descending aorta opening at T12

7)Splenic venous drainage VENOUS SINUSOIDS IN CORDS OFBILROTH8)Ambiguous genitalia AMBIGOUS GENITIAL is in female with excessof testosterone or in male with lack of testorone

9)Melanosis coli MELONOSIS COLI I is due over use of laxativescolonappers black in colour Melanosis coli is due to use of laxatives notantibiotics Usually anthraquinone ( senna and cascara)10)Inhalational antigen stimulation leading to antibodyrecovery from vaginal mucosa of experimental animalHow It is called Dissemination of Immunologic Memory and it is thesame mechanism used in Adenovirus Vaccine The adenovirus vaccine used by the military against adenovirus types 4and 7 is an enteric-coated live non-attenuated virus preparation This vaccine produces an asymptomatic intestinal infection and therebyinduces mucosal IgA memory cells These cells then populate the mucosal immune system throughout thebody ( Because Memory cells tend to home in a tissue-specific fashion presumably returning to the type of tissue in which they first

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encountered antigen)Vaccine recipients are thus protected against adenovirus acquired byaerosol which could otherwise produce pneumonia

11)x-ray foot with calcification parallel to firstmetatarsal with decreased dorsalis pedis myositis ossificens12)Ligament that holds tibia from goin back ant and posterior cruciateligments--- that holds tibia from going back is Posterior crusiate ligament -----ligament that prevents tibia from coming forward is Anterior cruciateligament13)Obturator nerve section effects obtutaror nerve injury leads to lossof adduction of thigh14)Pelvic ascites site of drainage on standing position the site ofdrainage is vescicouteric pouch in females and rectovescical poch inmales15)Aortic aneurysm rupture effect on urinalysis in thebackground of anuria aortic aneurysm leads to renal infarctionso therewill rbc in urine16)Hand decreased sensation lateral aspect median nerve injury17)Hand sensation ok but extention ofmetacarpophalangeal joints difficult exention and flexion are done bylumbricals and interossis muscles the extension at MP joint by---gtextensors of the fingersflexion at MP joint by---gtlumbricals and introssei so if extension isdifficult means extensors are weakwhich are supplied by radialnerve

18)Clubbing description choices bronchiectasis asthma clubbing isseen in bronchiectasis

Q1) Cystic fibrosis heterozygous frequency Q2) Chemotherapy heart failure acirceuroldquo left heartrightheartmyocardial fibrosis Maybe Doxorubicin (Adriamycin) FA p330 orDaunorubicin But have no idea what is the mechanismQ3) Stimulants and inhibitors of pancreatic secretionsexocrine and endocrine Exocrine- Stimulants CCK Secretin parasympathetics Inhibitors None Endocrine- Insulin Stimulants Glucose Amino Acid GIP Glucagon Insulin Inhibitors Somatostatin Sympathetics (Alpha) Glucagon Stimulants Amino acid Glucagon Inhibitors Insulin Somatostatin

Q4) Cellular barrier between gall bladder cavity andwallacirceurotrades epithelial cells is maybe asking for Tight junction Tightjunction must be there to protect the internal celluar structures fromnasty bileQ5) Embryology neural tube formation cellular dnafragmentation indicates Apoptosis Q6) War veteran describing killing business like acirceuroldquo defence mech

Q7) Trigeminal nerve nucleus identification in medulla ct cross section(you can just say verbally where its located) Q8) Efferent renal constriction effects on GFR ampFiltration fraction GFR amp FF both increasesQ9)Premature birth surfactant and steroid therapy fails due to surfacetension increasedecrease etc Q10) Barret esophageal cancer type Adenocarcinoma since barrettsis Metaplasia full of intesinal cellsQ11)GERD cuz of secretions from which type of gastric cells BRS Physiology(p223) says that the relaxaton of loweresophageal sphincter is vagally mediated and the neurotransmitter isVIP Or maybe GERD could be due to gastric acid therefore parietal cellcould be an answerQ12) Cholecystectomy patients absorb fat from Cholecystectomy ptwill still absorbing fat from terminal ileum I think well ofcourse fromsmall intestine cholecystectomy has nothing to do with the site ofabsorbtion the person still produces bile( in liver) just no storage or conecentrationof bile thats why post op cholecystectomy patients are put on low fatdiet

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but site of absorbtion remains small intestine (ileum) as usual

Q13)Sputum silver staining for bugs silver staining reminds me of twobugsbut I am not sure Pneumocysyis carinii Legionella pneumoniaeBut silver staining of PCP is done on pts Bronchoalveolar lavage IguessQ14) First thing to say to dad patient brought by 2daughters who express wish to remain with patientBest statement to make to build rapport with patientplaying crossword on encounter May be Doctor have to ask the ptwhether he wants their daughter in the room while interviewingQ15) Post break-up with boyfriend mother of patient finds synthroidtablets in nursing student daughteracirceurotrades belongings Docacirceurotrades responseto patient synthyroid is Thyroid hormone I guess but not sure if it isT3 or T4 the pt may be planning on weight loss because boyfriendhated her obesity q16)Fragile X family parents concern regarding testing of normal 14-year daughteracirceurotrades genome for similar problems Q 17) Girl child dumps classes since uncleacirceurotrades death and mother findsit helpful for daughter to be around home Intervention requiredFamily therapypsychotherapyacirceurobrvbaretc Q18) Porphyrias like the back of ur hands q19) Carbon tetrachloride how it affects liver CCl4 - The liver convertsCCl4 to a CCl3 free radical which damages the liver (fulminanthepatitis fatty change) from Goljans STARS pathology review p93

Acyclovir mechanism of action inhibhits DNA viral poymerase andphosphorylated by viral thymidine kinaseQ20) Hernia above n lateral to pubis Hernia above the inguinal lig isInguinal hernia and below the lig is femoral hernia So it could beboth Indirect and direct inguinal hernia since it doesnt say anythingabout hernias relation to inf epigastric vesselsQ21)Hydatidiform mole learn how to interpret genotypes of moles

Which 2 Joints are Never affected in RA Distal interphalangeal and theBack joints r never involved in RAQ1) Best means of bringing down temperature of seizingpatient with meningitis pharmacologic and otherwise think nonpharamacologic tt shd be hydrotherapy to bring down tempnpharamacologic may be paracetamol by rectal routeQ2) Acetaminophen overdose how it damages In overdose the storesof GSH are depleted and and the metabolite N-acetylbenzoquinoneiminereacts with hepatocytes leading to liver necrosis Acetaminophen formsfree radicals in the liver and results in fulminant hepatitis renalpapillary necrosisdamages by free radicals which r removed by glutathioneNACETYLCYSTEIN its antidote restores the glutathione levelsQ3) Antimicrosomal antibodies involved in hashimotos autoimmunethyroiditis and autoimmune hepatitisQ4)Dialysis patient on transplant list gets angry often and missesdialysis appointments - intervention need to spend more time withpatientdiscuss regardingreconsideration of transplant listacirceurobrvbaretc Dialysis patient on transplantlist gets angry often and misses dialysis appointments - interventionneed to spend more time with patientdiscuss regarding reconsiderationof transplant listacirceurobrvbaretc need to spend more time with patient toknow what exactly is his probQ5) Adenovirus acirceuroldquo structure nonenvelopedds linear DNA icosahedralnucleocapsid only virus with a fibre protruding from each of 12 verticesof teh capsidQ6) Brown fat of neonates Function site of heat production in aneonate---brown adipose tissue contain natural uncoupling proteinwhich allows energy loss in the form of heat to maintain basal tempQ7) Longterm steroid use effect on adrenals adrenal suppressiontherefore tapered slowly neg feed back on ant pit so decreased ACTHso less stim of adrenalsacirceurobrvbarhypothalamo pituitary axis and eventuallyleads to atrophy of the adrenal glandQ8) Trypanosome cruzi life cycle try cruzi lifecycle involves reduvidbud as a vector and both humans and animals as reservoirs life cycleacirceurobrvbar reservoirs are cats dogsacirceurobrvbar reduviid bug passes the trypomastigoteas it bites and scratching implants in bite siteacirceurobrvbaracirceurobrvbaracirceurobrvbarreservoir isrodents armadillos vector is reduviid bug it transmits the trypo-mastigote form which turns into the amastigote form inside the body Atthe bite site the lseion is called chagoma Systemic symptoms are

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fever lymphadenopathy Tachycardia meningoencephalitis Thencomes the intermediate phase where the patient is asymptomatic withlow levels of the parasite and antibodies against it decades later-thechronic form emerges with dilated cardiomyopathy megacolonmegaesophagusTreatment is NifurtimoxQ9)Patient requiring dialysis says donacirceurotradet want machines to keep mealive Docacirceurotrades next step Q10)Antifungals big time Drug interactions Mechanism of actions(letswrite few antifungals with mech of action and main side effectswe willnever forget it if we do so) amphotericin B binds ergosterol creates poresflucytosine-inhibit thymidilate synthaseazole-inhibit ergosterol synthesisgriesofulvin-interfere with microtubule functionterbinafine- inhibit squalene epoxideDRUG INERACTIONSAZOLE GRP INCREASE TOXICITY OF FOLL BY INHIBITING ITSMETABOLISMbdzcisapridecyclosporinefluoxetinelovastatinomeprazoleQ11) Alcoholic with nosebleed Wot to expect in terms of AST PT andforgotacirceurobrvbar( I dont know exactly whats being askedlets see who figuresit out) AST is increased platelet count is decreased prolonged PTQ12)Picture of normal hand and a slender hand shown and asked fordiagnosis Q13)Wernicke mammillary body identification on CT( here just name thestructures affected in wernickes encephalopathy and ofcourse do knowhow to identify themvery very HY) mammillary bodies anddorsomedial nucleus of thalamusacirceurobrvbarMamillary bodies on the ventralsurface of the brain stemQ14) How HBV causes liver cancer HBV DNA integrates in hostgenomic DNAMODIFICATIONOF GENE EXPRESSION HBVINCORPORATES itself into the hepatocyte dna and triggers malignantgrowth theres is a 200 X Risk of developing HCC in carriers versusnoncarriersQ15)Patient taking OCP Smoker Wot u wanna check first smokinginduces met enzymes increased metabolism of OCPSdecreased efficacySmoking itself is thrombogenic and estrogen also isacirceurobrvbar ask for historyof thrombosis may be check PT PTTQ16)Allopurinol acirceuroldquo effect on renal stones It inhibits xanthine oxidasedecreasing uric acidallopurinol used in pts of renal stones as calcium oxalate stone formersare hyperuricemicQ17)Radiation alopecia acirceuroldquo dermal histopathology sparse mixeddermal inflammatory infiltrate consisting mainly of lymphocytes Mucinous deposits confirmed by alcian bluePAS stain were observedwithin the epidermis of the hair follicleQ18)Streptococcus pyogenes acirceuroldquo patient penicillin allergicNext step Can give Clavulanic acid Sulbactam TazobactamCephalosporins should be avoided in patients allergic to penicillinbecause of cross sensitivity Cephalosporins are susceptible to betalactamase but less than penicillin penicillin allergic pts erythromycinor azithromycin are the alternatives all GRP A Streptoccoci r susceptibleto pencillin G but neither Rhematic fever nor allergic pats benefit frompencillin treatment after onset In pencillin allergies pats should geterythromycin or azithromycinHOWEVER ENTEROCOCCAL ENDOCARDITIS CAN BE ERADICATED ONLYBY PENICILLIN OR VANCOMYCIN COMBINED WITH ANAMINOGLYCOSIDEQ19)t-Rna triplet codon function The anti codon on the tRNA pairs withthe codon for aa in mRNA Q20) Nuclear membrane acirceuroldquo evolutionary importance betweeneukaryotes and prokaryotes all I know is nucleus membrane is absentin prokaryotes and present in euk may be evolutionary imp is to protectthe genetic information

there are 4 trigeminal nuclei---gt1)primary sensory nuclei for sensations of face2)spinal trigeminal nucleus for pain and tempreature sensation of face3)Mesencepahalic nucleus for proprioception4)primary motor nucleus for muscles of mastication

ZEBRA genesZ EBV replication activator (ZEBRA) as lytic cycle

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markersZEBRA is one of the immediate early genes of EBVit isconsidered to be expressed in the initial stage of the lytic cycle beforethe viral particles have been dispersed Zebra sign Hemorrhage is often characterized by a typical streakybleeding pattern due to blood spreading in the cerebellar sulci thiszebra-pattern hemorrhage seems to be typical in a postoperative lossof CSF Zebra bodies - lipid inclusions with concentric lamellar structure withalternating light and dark-staining bands in neuronal cells in neimannpicks Zebra tumor = acoustic neuromaQ1)Lead poisoning( symptoms) --Lead poisoningacirceurobrvbar lead inhibitsferrochelatase and ALA dehydraseacirceurobrvbar coproporhyrin and ALAaccumulate in urine sympacirceurordquoabdominal colic sideroblastic anemiawrist and foot drop lead lines in gingivae and epiphysis of long bonesencephalopathy basophilic stipplingQ2) Glutamine in urea cycle Q3) Large intestine gross section tumor shown Type(felt like the napkin constriction)I never heard of this kind oftumoranyone knows Q4) Radiation therapy pelvis Cause for urinary retention cystitsfibrosisQ5) Osteogenesis imperfecta defect d AD mutation in collagen genesQ6) Medial side of arm numbness after mastectomy nerve involvedintercostobrachial n also known as the lateral cutaneous br of theventral primary ramus of T2Q7) Interleukins big time Learn function of eachwe can namesomeand functionIL1- stim produced mainly by macrophages IL2 syn pyrogenic activates TH IL2- downreg TH2 Tcell growthfactor stim BcellIL3- stim BM stem cellsIL4-class switch to IgEIL5-Class swish to eosinophil promote B cell prolifIL6- produc of acute phase reactantsIL8-chemotactic and adhesion of neutrophilsIL10-Inhibit TH1 inhibit cytokine from macrophageIL12-induce TH0 to TH1Q8) Plummer Vinson esophageal defect Esophageal websacirceurobrvbar irondeficiency anemia o Stomatitis o Glossitis o Dysphagia o Spoon-shaped nails o Esophageal webs

Q9)Scurvy enzymereaction involved Prolyl and lysyl hydroxylase theenzymes that catalyzes the hydroxylation require vitamin CQ10)Reiter syndrome vs Sjogren Reiter syndrome--- urethritis conjunctivitis and ant uveitis arthritisSjogrenXerophthalmia xerostomia arthritis parotid enlargementQ11)Managing hypertensive crisis in MAO inhibitor patient on cheeseitacirceurotrades pathogenesis Treatment ot a Hypertensive Crisis from MAOIReactionThis is a medical emergency with cerebral vascular accidents being oneof the greatest concerns Medical consultation is warranted Patientsshould report to an immediately to an emergency department Initialtreatment options include Phentolamine 5 mg IV or Thorazine 50 to 100 mg po Care should be taken to ensure that the patient does not becomedangerously hypotensive or that the hypertensive state returns once theintervention medication has worn off Tyramine is actively transportedinto neurons and displaces NE leading to intraneuronal release of NEIt can be degraded by MAO but if you are on MAOI its interaction willcause tyramine build up Tons of NE will be replaced and hence theHTN crisisQ12) Neurotransmitter involved in Huntington Decreased GABA andAChQ13)Aortic coarctation site of constriction and symptoms infantile typeis preductal Cardiomegaly Pulmonary venous congestion RightVentricular HypertrophyAdult is postductal asso with notching of ribs Displaced esophagealshadow rightward Left Ventricular Hypertrophy HT in UL weak pulsesin LL

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Q14) Chronic antiplatelet drug in aspirin sensitive Clopidogrel ampTiclopidine They are back-up or alternative drugs to aspirin Theyblock ADP receptors on platelets hence decrease activationQ15)Stroke patient getting MI treated with streptokinasedies due to cva Cause concluded that death of the patient occurreddue to rebleeding on administration of streptokinase 1 IntracranialHemorrhage As PRS has mentioned the death could be due to intracranialhemorrhage Since CVA refers to both ischemic (80) andhemorrhagic(20)This is more likely than other explanation to me

2 Therapeutic Failure It could be due to strptokinases property itselfSince most individuals have had a streptococcal infection sometime intheir lives circulating antibodies against streptokinase are likely to bepresent in most patients These antibodies can combine withstreptokinase and neutralize its fibrinolytic properties (Therapeuticfailure)(lippincott Pharmacology 2nd edition p203) 3 Property of all Thrombolytic agents As the thrombolytic agents dissolute clot Increased local thrombinmay occur as the clot dissolves leading to enhanced plateletaggregability and thrombosis Strategies to prevent this includeadministration of antiplatelet drugs such as aspirin orantithrombotics such as heparin

Drugs that have been implicated in the development of serum sickness-like reactions include the following allopurinol (Zyloprim) arsenicalsand mercurial derivatives barbiturates captopril (Capoten)cephalosporins furazolidone (Furoxone) gold salts griseofulvin(Fulvicin Grifulvin) halothane hydralazine (Apresoline) iodidesmethyldopa para-aminosalicylic acid penicillamine penicillinsphenytoin (Dilantin) piperazine procainamide (Procan SR ProcanbidPronestyl-SR) quinidine (Quinaglute Quinalan Quinidex Quinora)streptokinase (Streptase Kabikinase) sulfonamides and thiouracils

Q16)Leukotriene inhibitors ZafirlukastacirceurobrvbarLT receptor antagonistQ17) Chromolyn sodium Mechanism of action prevent degranulation ofmast cellsQ18)Graveacirceurotrades pathophysiology autoimmune TSH receptor antibodiestype II hypersensitivityQ19) Couple in for infertility counseling High BMI Wifesays acirceuroœit kills me not to be able to have a babyacirceuroDocacirceurotrades best response obese wife possibly has Polycystic OvarianSyndrome (PCOS)74 of PCOS pt has infertility and PCOS accounts for 30 of overallinfertilityTherefore the doctor may have to evaluate for PCOS by Lab bloodtest and Ultrasonography The lab blood test will show Increasedandrogen LH fasting insulin prolactin and estrogens Theultrasonography is the most sensitive diagnostic study If the Dx of PCOS have been confirmed Tx should be Weightreduction quit smoking and antiandrogen(because of hirsutism) andantiestrogen(clomiphen)

Q20)Baby awakens at night frightened goes back to sleepDoes not respond to questions b parents on that awakening Best nextstep The boy is possibly having Night Terrors It occurs in Delta sleep so you cant wake them and they cant remember what happened Andnight terror is shown to be precursor to temporal lobe epilepsyThe doctors response should be either examine for any epilepsy in the pt(prevent or tx the temporal lobeepilepsy) or Identify amp dealing with waking-time anxiety to relieve night terrorsceliac disease is the proximal bowel and tropical sprue involves the entire bowel

Q1) Prematue ejaculation Best next step Ans- selective seratononreuptake inhibhitors like fluoxetine or even clorpramine (which is themost seratonin specific hetrocyclics)Q2)Delirium big time ( just define) Ans-Impaired conciousness(incontrast to dementia which is loss of

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

Remembered questions for STEP 1 - USMLE Forum

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

Remembered questions for STEP 1 - USMLE Forum

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

Remembered questions for STEP 1 - USMLE Forum

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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great idea heres my contributionan experience from a test thatwas taken earlier this week -

Biochem some key enzyme deficiency ones (Lesch Nyhan Maple SyrupDisease) but all of the questions were very obvious and did not requireyou to put much thought into it Dont blow off porphyria and leadpoisoning-- for some reason I got so many questions on that

Molecular Bio This was a big one lots of questions about DNAregulation transcription translation bacterial plasmids etc Sometimesthese questions look very scary -- they are always so long and use longnames for molecules or restriction enzymes that you have never heardof You need to get used to the question style and realize that whatthey are asking is very simple The NBME forms have questions verysimilar to the molecular bio ones I saw on the exam

Pharm Another one I thought would be difficult but not Big drugs youshould know a lot about (like antihypertensives drugs forhyperlipidemias cardic drugs etc) know side effects -- especially thechemo and immunosupressant drugs that kept on tripping me up somuch

MicroImmuno mostly bacterial processes and what you would use totreat them or what was their mechanism of disease (ie endotoxnexotoxin etc) Know immunology and cytokines well as well as thefunctions of all the cells Different immune deficiencies were all askedon my exam (there is one page in First Aid that sums them up verywell)

AnatomyNeuroanatomy Always combined with a pathology question oran imagine I had a few branchial plexuslumbar plexus questionsMany questions would give you a clinical scenario then ask you toidentiy the arterynerveorgan on a CT scanMRIangiogrambrain crosssection

Physio This was almost always combined with Pathology--they wouldask the physiology behind some path process I had so many questionswhere the question asked what would be the levels of x y and zenzymeshormones answer choices being increased decreased etc

Pathology lot of images -- MANY more than Qbanks representation

images from NBME test were repeated on my actual exam

Goljans book and lectures were great He pointed out lots of thingsthat wound up being on the exam and presents them in a way thatreally sticks Also his images are a great resource

as i already gave 1 qs which i heard from 1 of my frnd the qs is a female birth a baby who died soon after birth and her placenta wasedematous she has another child who goes to day carewat is thediagnosis of the child death1 ebv2 cmv3 parvovirusans is parvovirus

MLC - Most likely causeMLO - Most likely outome MLM - Most likely mechanismAE - adverse effect

MLM Cytochalasin D - actin polymerization diaphragm innervationtheophylline MOAVincristine MOACyclophosphamide - AEPotters syndrome - emb connectionSarcoidosis - hypercalcemia MLMADH MOAMLO paraxial mesoderm

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Paraneoplastic syn - SqCC AssociationMM - electrophoresis band patternApoptosis - blot picWNT 11 gene - nephro developmentRetinoic Acid - MOAgp 120abciximab AEOpen Angle glaucoma - RxBells palsy ML cause from a list of 10 or soIsoasthenuria MLCSpousal abuse next stepHS - AD disease - inheritance pattern from pedigreeMetanephrine VMA are metabolites in Nblastoma and Pheochromo -how would you differentiateBlunt trauma - damage to speenCT scan - medial meniscus - locateX ray skull - pit fossa - Sheehan syndromeACTH control over AC layersperoxidase - thyroid - HMP shunt connectionCarbamoyl Phos contribution to NT structureDavenport diagram - R-AlkalosisAs - Sq cell ca connectionzona pellucida glycoproteins

here is some stuff which i got just now1 anaphylaxis reaction in a ptgave epinephrine so wat mao of epi isans beta 2 effect2 placebo amp safety in which phase ans phase 13 turner synd pt has ammenorhea but she treted with estrogenprogesterone therapyto have regular menseturationshe want to bepregnant what possibility she haveans ova donation4 dantrolene moa 5 12 yr boy smooking cigratte and also steel mothers cigratte she isconcered abt itwat ans of a doca he send mom pap fprsmookingtherapyb he tells boy abt lung ca c give boy busprinone5 a pt have hypersensitivity bleeding easy brusing wat next complictionshe have ans was utrine rupture6 a pt have tetis and vagina a 5alpha redutase def Bdihydrotestosterone defc receptor respond ans c7 predisposition ovarian ca8 a female brt grand pa to doc he had alziemerswhen doc chek hefound stages of healing ans was elder abuse9 which heart diesease in turner10 64 yr old male bone pain lytic lesion ans multiple fracture11 a 16 yr old grl bt inc pt incwhich factor absent ans 812 moa of cholestyramine13 in copd contraindicated drug is proparanol14 asthma frst line of tretment15 2 qs abt dilated cardiomyopathy16 5 qs abt b12 def17 moa cisplatin18 a women homeless live near by pesticide comp he sensoryinnervation goneand has stocking glove pattern skin infectionwat is thecoz a lead poisioning b leprosy ans is b19 a pt whose daughter took him to er tell abt she found near herfather bed theophyline bottle codine albuterolthr is some more historywat treatment shld antidote naloxaone

Q) on how would you differentiate bt Klebsiella from Salmonella ALactose fermentation

Q) about Lesch Nyhan Syndrome- What Accumulates A uric acid

Q)drug of choice for increased VLDL A Niacin

Q) asks about what part of the Antibody binds to cells A FC portion

Q) describes a child with eczema low platelets and immune def- askdiagnosis A Wiscott Aldrich Syndrome

Dx of herpes vesicular painful lesions2 Conversion disorder saying pt paralyzed on one side3 Schizotypal DO pt lives with a lot of cats and is happy by herself4 Sublimation defense mechanism burned victum goes out for fund

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raising5 Arteriogram of ACA pt with lower exteremity paralysis6 MRI of spine shown pt cant feel pain and temp on lowerexteremites7 Esophageal veins initiates from what vein8 Gag reflex9 Thymus anatomical location between manubrium and hyoid bone10 1st part of doudinum fed by what artery11 loss of dorsiflexion what nerve12 what artery supplies testicles where does it comes from13 what nerve supplies anal area14 Histologic pic shown Dx Diabetic GN15 IgA def pulmonary problems Dx16 Described skin infection DXHZV17 Arrest of ovum prophase I18 40 yo undecended testes his spermatogonia is in what phasehaploid diploid n 2n19 Odd ratio just simply know the formula20 Beta error 1-B 90 (dont recall the whole thing

21 Case control study retrospective22 Describe specifity23 eyes can not do lateral gase but looking down and up is ok Whatnerve damaged24 pt can not look medially what nerve damaged25 Renal cell carcinomavit D26 Thyroxine T4 activates what receptor eg thyrosine kinase27 Steroid receptors28 PDAcyanosiscontinious murmur at the ApexgtL hrthyperthpy29 Older pt calcification of valves vegitation30 Heme synthesis option was Succinyl CoA

PX with signs amp symptoms of goodpasture what would lm show onbiopsycresentphoto of plasma cella pt with lytic lesion vertebra wat diseasewat drug usually given pretreatment for leukemiamoa of doxurubicinmoa abacavir(ans reverse transcriptase inhibitor)ho pt having gynecomastia labast alt incans ketoconazola Diag exactlly 4m frst aid ans chancrestaright qs abt BPHASKING qs abt endometriosispedigree of mito inheritancecleft lip failure of watcase of alcholic hepatitisho UMN lesion identify the lesion MRICASE SENSITIVITY AND SPECIFICITYpt having wt lose some psychtic symptom dilated pupil asking abt drugabuset

31 Rate limiting step in heme synthesisacirceurobrvbarALA32 steatoureaacirceurobrvbarbc of HMG-CoA reductase33 what is increased in lack of HMG-CoA reductaseTriglycerides Chylomicrons34 pt Macrocytic neurological defacirceurobrvbargtB12 def35 pt with gastritis fundus region anti-bodyagainst IFacirceurobrvbarwhat will be deficient36 B12 def acirceurobrvbarterminal illium37 Described Chronacirceurotrades dizacirceurobrvbarasked lesions are whereJujunium with bloody diarrhea38 Rhumatiod arthritis39 Pic of swallen finger Septic arthritis40 pic of small petichia on skinacirceurobrvbarwhat is def vit Cdef

PT in hot sun gets red on her faceacirceurobrvbarbc of Options Melanocytes-ADA deficient what cumulates Options Adenineuric acid urea- MOA Colchicine- pt has low O2 satacirceurobrvbar 75 bc of options 23BPG

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decreasedacirceurobrvbar- acirceurotrades given DM1 ketoacidosis MetabolicAlkolysis and acidosis- post-op 7 days MRI shownacirceurobrvbaroption PE- UTI older pt no Ecoli in the optionsacirceurobrvbarbut G-diplocco- Picnic meat watery diaacirceurobrvbarwhat bug Optionscamplobacter juju strep saphraticus c basillus - Pt With bloody diarrhea what bug - umbilical vein or artery thrombus to wherecauses cerebral infarct why Options open foramensecondum- VQ mismatch options perfusion decreased atapex or higher O2

acirceurobrvbarKNOW ENDOCRINE PHYSIOLOGY AND PATHOPHYSIOLOGY acirceurobrvbaracirceurobrvbar Know your vitamins very wellImmuno-know all the cytokines neuro - know the cerebral cortex very wellall the areas-brocaswernickes etcmany questions on spinal cord segmentsmost of the neuro questionswere based on imagesa nurse use iodine before giving insulin why--to sterlize that areafrom virusbacteria and fungi a girl has 28 days cyclephyscian do her hormone teston the day26 what hormone will be increase ---option are FSHLHTSHHCG MAKE SURE HOW TO READ CT SCANS AND MRIS THE ANATOMYQUESTIONS HAD ALOT OF CT SCANS SHOWING VARIOUS MUSCLESLike for example some person had a superior gluteal nerve lesion andit had a CT scan of the pelvis and you had to identify the MUSCLEAlso 2 QUESTIONS ON EPIDURAL HEMATOMA ASKED WHICH ARTERYIS DAMAGED FETAL ALCOHOL SYNDROME KNOW THE SIGNS (DONT GETCONFUSED WITH DOWNS SYNDROME)HYPERHYPO THYROIDISM

1)Pituitary tumor on visual fields PITUTARY TUMOUR ISCRANIOPHRANGIOMA CAUSES BITEMPORAL HEMIANOPSIA

2)Tumor anterior to temporal fossa affects wot 3)Tends to fall to one side tongue deviates to othersite of lesion THIS is problem in 12 cranial nerve which is locted inlower medulla4)Pediatric infratentorial tumor most of the paediatric tumours areinfra tentorialthey are celleblarastrocytoma2medulloblastoma3gliomas

5)Midline neck mass at level of hyoid BRANCHIAL CYST

6)Esophagal hiatus of diaphragm IT OPENS AT THE LEVEL OF T10 IVChiatus at T8descending aorta opening at T12

7)Splenic venous drainage VENOUS SINUSOIDS IN CORDS OFBILROTH8)Ambiguous genitalia AMBIGOUS GENITIAL is in female with excessof testosterone or in male with lack of testorone

9)Melanosis coli MELONOSIS COLI I is due over use of laxativescolonappers black in colour Melanosis coli is due to use of laxatives notantibiotics Usually anthraquinone ( senna and cascara)10)Inhalational antigen stimulation leading to antibodyrecovery from vaginal mucosa of experimental animalHow It is called Dissemination of Immunologic Memory and it is thesame mechanism used in Adenovirus Vaccine The adenovirus vaccine used by the military against adenovirus types 4and 7 is an enteric-coated live non-attenuated virus preparation This vaccine produces an asymptomatic intestinal infection and therebyinduces mucosal IgA memory cells These cells then populate the mucosal immune system throughout thebody ( Because Memory cells tend to home in a tissue-specific fashion presumably returning to the type of tissue in which they first

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encountered antigen)Vaccine recipients are thus protected against adenovirus acquired byaerosol which could otherwise produce pneumonia

11)x-ray foot with calcification parallel to firstmetatarsal with decreased dorsalis pedis myositis ossificens12)Ligament that holds tibia from goin back ant and posterior cruciateligments--- that holds tibia from going back is Posterior crusiate ligament -----ligament that prevents tibia from coming forward is Anterior cruciateligament13)Obturator nerve section effects obtutaror nerve injury leads to lossof adduction of thigh14)Pelvic ascites site of drainage on standing position the site ofdrainage is vescicouteric pouch in females and rectovescical poch inmales15)Aortic aneurysm rupture effect on urinalysis in thebackground of anuria aortic aneurysm leads to renal infarctionso therewill rbc in urine16)Hand decreased sensation lateral aspect median nerve injury17)Hand sensation ok but extention ofmetacarpophalangeal joints difficult exention and flexion are done bylumbricals and interossis muscles the extension at MP joint by---gtextensors of the fingersflexion at MP joint by---gtlumbricals and introssei so if extension isdifficult means extensors are weakwhich are supplied by radialnerve

18)Clubbing description choices bronchiectasis asthma clubbing isseen in bronchiectasis

Q1) Cystic fibrosis heterozygous frequency Q2) Chemotherapy heart failure acirceuroldquo left heartrightheartmyocardial fibrosis Maybe Doxorubicin (Adriamycin) FA p330 orDaunorubicin But have no idea what is the mechanismQ3) Stimulants and inhibitors of pancreatic secretionsexocrine and endocrine Exocrine- Stimulants CCK Secretin parasympathetics Inhibitors None Endocrine- Insulin Stimulants Glucose Amino Acid GIP Glucagon Insulin Inhibitors Somatostatin Sympathetics (Alpha) Glucagon Stimulants Amino acid Glucagon Inhibitors Insulin Somatostatin

Q4) Cellular barrier between gall bladder cavity andwallacirceurotrades epithelial cells is maybe asking for Tight junction Tightjunction must be there to protect the internal celluar structures fromnasty bileQ5) Embryology neural tube formation cellular dnafragmentation indicates Apoptosis Q6) War veteran describing killing business like acirceuroldquo defence mech

Q7) Trigeminal nerve nucleus identification in medulla ct cross section(you can just say verbally where its located) Q8) Efferent renal constriction effects on GFR ampFiltration fraction GFR amp FF both increasesQ9)Premature birth surfactant and steroid therapy fails due to surfacetension increasedecrease etc Q10) Barret esophageal cancer type Adenocarcinoma since barrettsis Metaplasia full of intesinal cellsQ11)GERD cuz of secretions from which type of gastric cells BRS Physiology(p223) says that the relaxaton of loweresophageal sphincter is vagally mediated and the neurotransmitter isVIP Or maybe GERD could be due to gastric acid therefore parietal cellcould be an answerQ12) Cholecystectomy patients absorb fat from Cholecystectomy ptwill still absorbing fat from terminal ileum I think well ofcourse fromsmall intestine cholecystectomy has nothing to do with the site ofabsorbtion the person still produces bile( in liver) just no storage or conecentrationof bile thats why post op cholecystectomy patients are put on low fatdiet

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but site of absorbtion remains small intestine (ileum) as usual

Q13)Sputum silver staining for bugs silver staining reminds me of twobugsbut I am not sure Pneumocysyis carinii Legionella pneumoniaeBut silver staining of PCP is done on pts Bronchoalveolar lavage IguessQ14) First thing to say to dad patient brought by 2daughters who express wish to remain with patientBest statement to make to build rapport with patientplaying crossword on encounter May be Doctor have to ask the ptwhether he wants their daughter in the room while interviewingQ15) Post break-up with boyfriend mother of patient finds synthroidtablets in nursing student daughteracirceurotrades belongings Docacirceurotrades responseto patient synthyroid is Thyroid hormone I guess but not sure if it isT3 or T4 the pt may be planning on weight loss because boyfriendhated her obesity q16)Fragile X family parents concern regarding testing of normal 14-year daughteracirceurotrades genome for similar problems Q 17) Girl child dumps classes since uncleacirceurotrades death and mother findsit helpful for daughter to be around home Intervention requiredFamily therapypsychotherapyacirceurobrvbaretc Q18) Porphyrias like the back of ur hands q19) Carbon tetrachloride how it affects liver CCl4 - The liver convertsCCl4 to a CCl3 free radical which damages the liver (fulminanthepatitis fatty change) from Goljans STARS pathology review p93

Acyclovir mechanism of action inhibhits DNA viral poymerase andphosphorylated by viral thymidine kinaseQ20) Hernia above n lateral to pubis Hernia above the inguinal lig isInguinal hernia and below the lig is femoral hernia So it could beboth Indirect and direct inguinal hernia since it doesnt say anythingabout hernias relation to inf epigastric vesselsQ21)Hydatidiform mole learn how to interpret genotypes of moles

Which 2 Joints are Never affected in RA Distal interphalangeal and theBack joints r never involved in RAQ1) Best means of bringing down temperature of seizingpatient with meningitis pharmacologic and otherwise think nonpharamacologic tt shd be hydrotherapy to bring down tempnpharamacologic may be paracetamol by rectal routeQ2) Acetaminophen overdose how it damages In overdose the storesof GSH are depleted and and the metabolite N-acetylbenzoquinoneiminereacts with hepatocytes leading to liver necrosis Acetaminophen formsfree radicals in the liver and results in fulminant hepatitis renalpapillary necrosisdamages by free radicals which r removed by glutathioneNACETYLCYSTEIN its antidote restores the glutathione levelsQ3) Antimicrosomal antibodies involved in hashimotos autoimmunethyroiditis and autoimmune hepatitisQ4)Dialysis patient on transplant list gets angry often and missesdialysis appointments - intervention need to spend more time withpatientdiscuss regardingreconsideration of transplant listacirceurobrvbaretc Dialysis patient on transplantlist gets angry often and misses dialysis appointments - interventionneed to spend more time with patientdiscuss regarding reconsiderationof transplant listacirceurobrvbaretc need to spend more time with patient toknow what exactly is his probQ5) Adenovirus acirceuroldquo structure nonenvelopedds linear DNA icosahedralnucleocapsid only virus with a fibre protruding from each of 12 verticesof teh capsidQ6) Brown fat of neonates Function site of heat production in aneonate---brown adipose tissue contain natural uncoupling proteinwhich allows energy loss in the form of heat to maintain basal tempQ7) Longterm steroid use effect on adrenals adrenal suppressiontherefore tapered slowly neg feed back on ant pit so decreased ACTHso less stim of adrenalsacirceurobrvbarhypothalamo pituitary axis and eventuallyleads to atrophy of the adrenal glandQ8) Trypanosome cruzi life cycle try cruzi lifecycle involves reduvidbud as a vector and both humans and animals as reservoirs life cycleacirceurobrvbar reservoirs are cats dogsacirceurobrvbar reduviid bug passes the trypomastigoteas it bites and scratching implants in bite siteacirceurobrvbaracirceurobrvbaracirceurobrvbarreservoir isrodents armadillos vector is reduviid bug it transmits the trypo-mastigote form which turns into the amastigote form inside the body Atthe bite site the lseion is called chagoma Systemic symptoms are

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fever lymphadenopathy Tachycardia meningoencephalitis Thencomes the intermediate phase where the patient is asymptomatic withlow levels of the parasite and antibodies against it decades later-thechronic form emerges with dilated cardiomyopathy megacolonmegaesophagusTreatment is NifurtimoxQ9)Patient requiring dialysis says donacirceurotradet want machines to keep mealive Docacirceurotrades next step Q10)Antifungals big time Drug interactions Mechanism of actions(letswrite few antifungals with mech of action and main side effectswe willnever forget it if we do so) amphotericin B binds ergosterol creates poresflucytosine-inhibit thymidilate synthaseazole-inhibit ergosterol synthesisgriesofulvin-interfere with microtubule functionterbinafine- inhibit squalene epoxideDRUG INERACTIONSAZOLE GRP INCREASE TOXICITY OF FOLL BY INHIBITING ITSMETABOLISMbdzcisapridecyclosporinefluoxetinelovastatinomeprazoleQ11) Alcoholic with nosebleed Wot to expect in terms of AST PT andforgotacirceurobrvbar( I dont know exactly whats being askedlets see who figuresit out) AST is increased platelet count is decreased prolonged PTQ12)Picture of normal hand and a slender hand shown and asked fordiagnosis Q13)Wernicke mammillary body identification on CT( here just name thestructures affected in wernickes encephalopathy and ofcourse do knowhow to identify themvery very HY) mammillary bodies anddorsomedial nucleus of thalamusacirceurobrvbarMamillary bodies on the ventralsurface of the brain stemQ14) How HBV causes liver cancer HBV DNA integrates in hostgenomic DNAMODIFICATIONOF GENE EXPRESSION HBVINCORPORATES itself into the hepatocyte dna and triggers malignantgrowth theres is a 200 X Risk of developing HCC in carriers versusnoncarriersQ15)Patient taking OCP Smoker Wot u wanna check first smokinginduces met enzymes increased metabolism of OCPSdecreased efficacySmoking itself is thrombogenic and estrogen also isacirceurobrvbar ask for historyof thrombosis may be check PT PTTQ16)Allopurinol acirceuroldquo effect on renal stones It inhibits xanthine oxidasedecreasing uric acidallopurinol used in pts of renal stones as calcium oxalate stone formersare hyperuricemicQ17)Radiation alopecia acirceuroldquo dermal histopathology sparse mixeddermal inflammatory infiltrate consisting mainly of lymphocytes Mucinous deposits confirmed by alcian bluePAS stain were observedwithin the epidermis of the hair follicleQ18)Streptococcus pyogenes acirceuroldquo patient penicillin allergicNext step Can give Clavulanic acid Sulbactam TazobactamCephalosporins should be avoided in patients allergic to penicillinbecause of cross sensitivity Cephalosporins are susceptible to betalactamase but less than penicillin penicillin allergic pts erythromycinor azithromycin are the alternatives all GRP A Streptoccoci r susceptibleto pencillin G but neither Rhematic fever nor allergic pats benefit frompencillin treatment after onset In pencillin allergies pats should geterythromycin or azithromycinHOWEVER ENTEROCOCCAL ENDOCARDITIS CAN BE ERADICATED ONLYBY PENICILLIN OR VANCOMYCIN COMBINED WITH ANAMINOGLYCOSIDEQ19)t-Rna triplet codon function The anti codon on the tRNA pairs withthe codon for aa in mRNA Q20) Nuclear membrane acirceuroldquo evolutionary importance betweeneukaryotes and prokaryotes all I know is nucleus membrane is absentin prokaryotes and present in euk may be evolutionary imp is to protectthe genetic information

there are 4 trigeminal nuclei---gt1)primary sensory nuclei for sensations of face2)spinal trigeminal nucleus for pain and tempreature sensation of face3)Mesencepahalic nucleus for proprioception4)primary motor nucleus for muscles of mastication

ZEBRA genesZ EBV replication activator (ZEBRA) as lytic cycle

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markersZEBRA is one of the immediate early genes of EBVit isconsidered to be expressed in the initial stage of the lytic cycle beforethe viral particles have been dispersed Zebra sign Hemorrhage is often characterized by a typical streakybleeding pattern due to blood spreading in the cerebellar sulci thiszebra-pattern hemorrhage seems to be typical in a postoperative lossof CSF Zebra bodies - lipid inclusions with concentric lamellar structure withalternating light and dark-staining bands in neuronal cells in neimannpicks Zebra tumor = acoustic neuromaQ1)Lead poisoning( symptoms) --Lead poisoningacirceurobrvbar lead inhibitsferrochelatase and ALA dehydraseacirceurobrvbar coproporhyrin and ALAaccumulate in urine sympacirceurordquoabdominal colic sideroblastic anemiawrist and foot drop lead lines in gingivae and epiphysis of long bonesencephalopathy basophilic stipplingQ2) Glutamine in urea cycle Q3) Large intestine gross section tumor shown Type(felt like the napkin constriction)I never heard of this kind oftumoranyone knows Q4) Radiation therapy pelvis Cause for urinary retention cystitsfibrosisQ5) Osteogenesis imperfecta defect d AD mutation in collagen genesQ6) Medial side of arm numbness after mastectomy nerve involvedintercostobrachial n also known as the lateral cutaneous br of theventral primary ramus of T2Q7) Interleukins big time Learn function of eachwe can namesomeand functionIL1- stim produced mainly by macrophages IL2 syn pyrogenic activates TH IL2- downreg TH2 Tcell growthfactor stim BcellIL3- stim BM stem cellsIL4-class switch to IgEIL5-Class swish to eosinophil promote B cell prolifIL6- produc of acute phase reactantsIL8-chemotactic and adhesion of neutrophilsIL10-Inhibit TH1 inhibit cytokine from macrophageIL12-induce TH0 to TH1Q8) Plummer Vinson esophageal defect Esophageal websacirceurobrvbar irondeficiency anemia o Stomatitis o Glossitis o Dysphagia o Spoon-shaped nails o Esophageal webs

Q9)Scurvy enzymereaction involved Prolyl and lysyl hydroxylase theenzymes that catalyzes the hydroxylation require vitamin CQ10)Reiter syndrome vs Sjogren Reiter syndrome--- urethritis conjunctivitis and ant uveitis arthritisSjogrenXerophthalmia xerostomia arthritis parotid enlargementQ11)Managing hypertensive crisis in MAO inhibitor patient on cheeseitacirceurotrades pathogenesis Treatment ot a Hypertensive Crisis from MAOIReactionThis is a medical emergency with cerebral vascular accidents being oneof the greatest concerns Medical consultation is warranted Patientsshould report to an immediately to an emergency department Initialtreatment options include Phentolamine 5 mg IV or Thorazine 50 to 100 mg po Care should be taken to ensure that the patient does not becomedangerously hypotensive or that the hypertensive state returns once theintervention medication has worn off Tyramine is actively transportedinto neurons and displaces NE leading to intraneuronal release of NEIt can be degraded by MAO but if you are on MAOI its interaction willcause tyramine build up Tons of NE will be replaced and hence theHTN crisisQ12) Neurotransmitter involved in Huntington Decreased GABA andAChQ13)Aortic coarctation site of constriction and symptoms infantile typeis preductal Cardiomegaly Pulmonary venous congestion RightVentricular HypertrophyAdult is postductal asso with notching of ribs Displaced esophagealshadow rightward Left Ventricular Hypertrophy HT in UL weak pulsesin LL

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Q14) Chronic antiplatelet drug in aspirin sensitive Clopidogrel ampTiclopidine They are back-up or alternative drugs to aspirin Theyblock ADP receptors on platelets hence decrease activationQ15)Stroke patient getting MI treated with streptokinasedies due to cva Cause concluded that death of the patient occurreddue to rebleeding on administration of streptokinase 1 IntracranialHemorrhage As PRS has mentioned the death could be due to intracranialhemorrhage Since CVA refers to both ischemic (80) andhemorrhagic(20)This is more likely than other explanation to me

2 Therapeutic Failure It could be due to strptokinases property itselfSince most individuals have had a streptococcal infection sometime intheir lives circulating antibodies against streptokinase are likely to bepresent in most patients These antibodies can combine withstreptokinase and neutralize its fibrinolytic properties (Therapeuticfailure)(lippincott Pharmacology 2nd edition p203) 3 Property of all Thrombolytic agents As the thrombolytic agents dissolute clot Increased local thrombinmay occur as the clot dissolves leading to enhanced plateletaggregability and thrombosis Strategies to prevent this includeadministration of antiplatelet drugs such as aspirin orantithrombotics such as heparin

Drugs that have been implicated in the development of serum sickness-like reactions include the following allopurinol (Zyloprim) arsenicalsand mercurial derivatives barbiturates captopril (Capoten)cephalosporins furazolidone (Furoxone) gold salts griseofulvin(Fulvicin Grifulvin) halothane hydralazine (Apresoline) iodidesmethyldopa para-aminosalicylic acid penicillamine penicillinsphenytoin (Dilantin) piperazine procainamide (Procan SR ProcanbidPronestyl-SR) quinidine (Quinaglute Quinalan Quinidex Quinora)streptokinase (Streptase Kabikinase) sulfonamides and thiouracils

Q16)Leukotriene inhibitors ZafirlukastacirceurobrvbarLT receptor antagonistQ17) Chromolyn sodium Mechanism of action prevent degranulation ofmast cellsQ18)Graveacirceurotrades pathophysiology autoimmune TSH receptor antibodiestype II hypersensitivityQ19) Couple in for infertility counseling High BMI Wifesays acirceuroœit kills me not to be able to have a babyacirceuroDocacirceurotrades best response obese wife possibly has Polycystic OvarianSyndrome (PCOS)74 of PCOS pt has infertility and PCOS accounts for 30 of overallinfertilityTherefore the doctor may have to evaluate for PCOS by Lab bloodtest and Ultrasonography The lab blood test will show Increasedandrogen LH fasting insulin prolactin and estrogens Theultrasonography is the most sensitive diagnostic study If the Dx of PCOS have been confirmed Tx should be Weightreduction quit smoking and antiandrogen(because of hirsutism) andantiestrogen(clomiphen)

Q20)Baby awakens at night frightened goes back to sleepDoes not respond to questions b parents on that awakening Best nextstep The boy is possibly having Night Terrors It occurs in Delta sleep so you cant wake them and they cant remember what happened Andnight terror is shown to be precursor to temporal lobe epilepsyThe doctors response should be either examine for any epilepsy in the pt(prevent or tx the temporal lobeepilepsy) or Identify amp dealing with waking-time anxiety to relieve night terrorsceliac disease is the proximal bowel and tropical sprue involves the entire bowel

Q1) Prematue ejaculation Best next step Ans- selective seratononreuptake inhibhitors like fluoxetine or even clorpramine (which is themost seratonin specific hetrocyclics)Q2)Delirium big time ( just define) Ans-Impaired conciousness(incontrast to dementia which is loss of

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

Remembered questions for STEP 1 - USMLE Forum

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Paraneoplastic syn - SqCC AssociationMM - electrophoresis band patternApoptosis - blot picWNT 11 gene - nephro developmentRetinoic Acid - MOAgp 120abciximab AEOpen Angle glaucoma - RxBells palsy ML cause from a list of 10 or soIsoasthenuria MLCSpousal abuse next stepHS - AD disease - inheritance pattern from pedigreeMetanephrine VMA are metabolites in Nblastoma and Pheochromo -how would you differentiateBlunt trauma - damage to speenCT scan - medial meniscus - locateX ray skull - pit fossa - Sheehan syndromeACTH control over AC layersperoxidase - thyroid - HMP shunt connectionCarbamoyl Phos contribution to NT structureDavenport diagram - R-AlkalosisAs - Sq cell ca connectionzona pellucida glycoproteins

here is some stuff which i got just now1 anaphylaxis reaction in a ptgave epinephrine so wat mao of epi isans beta 2 effect2 placebo amp safety in which phase ans phase 13 turner synd pt has ammenorhea but she treted with estrogenprogesterone therapyto have regular menseturationshe want to bepregnant what possibility she haveans ova donation4 dantrolene moa 5 12 yr boy smooking cigratte and also steel mothers cigratte she isconcered abt itwat ans of a doca he send mom pap fprsmookingtherapyb he tells boy abt lung ca c give boy busprinone5 a pt have hypersensitivity bleeding easy brusing wat next complictionshe have ans was utrine rupture6 a pt have tetis and vagina a 5alpha redutase def Bdihydrotestosterone defc receptor respond ans c7 predisposition ovarian ca8 a female brt grand pa to doc he had alziemerswhen doc chek hefound stages of healing ans was elder abuse9 which heart diesease in turner10 64 yr old male bone pain lytic lesion ans multiple fracture11 a 16 yr old grl bt inc pt incwhich factor absent ans 812 moa of cholestyramine13 in copd contraindicated drug is proparanol14 asthma frst line of tretment15 2 qs abt dilated cardiomyopathy16 5 qs abt b12 def17 moa cisplatin18 a women homeless live near by pesticide comp he sensoryinnervation goneand has stocking glove pattern skin infectionwat is thecoz a lead poisioning b leprosy ans is b19 a pt whose daughter took him to er tell abt she found near herfather bed theophyline bottle codine albuterolthr is some more historywat treatment shld antidote naloxaone

Q) on how would you differentiate bt Klebsiella from Salmonella ALactose fermentation

Q) about Lesch Nyhan Syndrome- What Accumulates A uric acid

Q)drug of choice for increased VLDL A Niacin

Q) asks about what part of the Antibody binds to cells A FC portion

Q) describes a child with eczema low platelets and immune def- askdiagnosis A Wiscott Aldrich Syndrome

Dx of herpes vesicular painful lesions2 Conversion disorder saying pt paralyzed on one side3 Schizotypal DO pt lives with a lot of cats and is happy by herself4 Sublimation defense mechanism burned victum goes out for fund

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raising5 Arteriogram of ACA pt with lower exteremity paralysis6 MRI of spine shown pt cant feel pain and temp on lowerexteremites7 Esophageal veins initiates from what vein8 Gag reflex9 Thymus anatomical location between manubrium and hyoid bone10 1st part of doudinum fed by what artery11 loss of dorsiflexion what nerve12 what artery supplies testicles where does it comes from13 what nerve supplies anal area14 Histologic pic shown Dx Diabetic GN15 IgA def pulmonary problems Dx16 Described skin infection DXHZV17 Arrest of ovum prophase I18 40 yo undecended testes his spermatogonia is in what phasehaploid diploid n 2n19 Odd ratio just simply know the formula20 Beta error 1-B 90 (dont recall the whole thing

21 Case control study retrospective22 Describe specifity23 eyes can not do lateral gase but looking down and up is ok Whatnerve damaged24 pt can not look medially what nerve damaged25 Renal cell carcinomavit D26 Thyroxine T4 activates what receptor eg thyrosine kinase27 Steroid receptors28 PDAcyanosiscontinious murmur at the ApexgtL hrthyperthpy29 Older pt calcification of valves vegitation30 Heme synthesis option was Succinyl CoA

PX with signs amp symptoms of goodpasture what would lm show onbiopsycresentphoto of plasma cella pt with lytic lesion vertebra wat diseasewat drug usually given pretreatment for leukemiamoa of doxurubicinmoa abacavir(ans reverse transcriptase inhibitor)ho pt having gynecomastia labast alt incans ketoconazola Diag exactlly 4m frst aid ans chancrestaright qs abt BPHASKING qs abt endometriosispedigree of mito inheritancecleft lip failure of watcase of alcholic hepatitisho UMN lesion identify the lesion MRICASE SENSITIVITY AND SPECIFICITYpt having wt lose some psychtic symptom dilated pupil asking abt drugabuset

31 Rate limiting step in heme synthesisacirceurobrvbarALA32 steatoureaacirceurobrvbarbc of HMG-CoA reductase33 what is increased in lack of HMG-CoA reductaseTriglycerides Chylomicrons34 pt Macrocytic neurological defacirceurobrvbargtB12 def35 pt with gastritis fundus region anti-bodyagainst IFacirceurobrvbarwhat will be deficient36 B12 def acirceurobrvbarterminal illium37 Described Chronacirceurotrades dizacirceurobrvbarasked lesions are whereJujunium with bloody diarrhea38 Rhumatiod arthritis39 Pic of swallen finger Septic arthritis40 pic of small petichia on skinacirceurobrvbarwhat is def vit Cdef

PT in hot sun gets red on her faceacirceurobrvbarbc of Options Melanocytes-ADA deficient what cumulates Options Adenineuric acid urea- MOA Colchicine- pt has low O2 satacirceurobrvbar 75 bc of options 23BPG

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decreasedacirceurobrvbar- acirceurotrades given DM1 ketoacidosis MetabolicAlkolysis and acidosis- post-op 7 days MRI shownacirceurobrvbaroption PE- UTI older pt no Ecoli in the optionsacirceurobrvbarbut G-diplocco- Picnic meat watery diaacirceurobrvbarwhat bug Optionscamplobacter juju strep saphraticus c basillus - Pt With bloody diarrhea what bug - umbilical vein or artery thrombus to wherecauses cerebral infarct why Options open foramensecondum- VQ mismatch options perfusion decreased atapex or higher O2

acirceurobrvbarKNOW ENDOCRINE PHYSIOLOGY AND PATHOPHYSIOLOGY acirceurobrvbaracirceurobrvbar Know your vitamins very wellImmuno-know all the cytokines neuro - know the cerebral cortex very wellall the areas-brocaswernickes etcmany questions on spinal cord segmentsmost of the neuro questionswere based on imagesa nurse use iodine before giving insulin why--to sterlize that areafrom virusbacteria and fungi a girl has 28 days cyclephyscian do her hormone teston the day26 what hormone will be increase ---option are FSHLHTSHHCG MAKE SURE HOW TO READ CT SCANS AND MRIS THE ANATOMYQUESTIONS HAD ALOT OF CT SCANS SHOWING VARIOUS MUSCLESLike for example some person had a superior gluteal nerve lesion andit had a CT scan of the pelvis and you had to identify the MUSCLEAlso 2 QUESTIONS ON EPIDURAL HEMATOMA ASKED WHICH ARTERYIS DAMAGED FETAL ALCOHOL SYNDROME KNOW THE SIGNS (DONT GETCONFUSED WITH DOWNS SYNDROME)HYPERHYPO THYROIDISM

1)Pituitary tumor on visual fields PITUTARY TUMOUR ISCRANIOPHRANGIOMA CAUSES BITEMPORAL HEMIANOPSIA

2)Tumor anterior to temporal fossa affects wot 3)Tends to fall to one side tongue deviates to othersite of lesion THIS is problem in 12 cranial nerve which is locted inlower medulla4)Pediatric infratentorial tumor most of the paediatric tumours areinfra tentorialthey are celleblarastrocytoma2medulloblastoma3gliomas

5)Midline neck mass at level of hyoid BRANCHIAL CYST

6)Esophagal hiatus of diaphragm IT OPENS AT THE LEVEL OF T10 IVChiatus at T8descending aorta opening at T12

7)Splenic venous drainage VENOUS SINUSOIDS IN CORDS OFBILROTH8)Ambiguous genitalia AMBIGOUS GENITIAL is in female with excessof testosterone or in male with lack of testorone

9)Melanosis coli MELONOSIS COLI I is due over use of laxativescolonappers black in colour Melanosis coli is due to use of laxatives notantibiotics Usually anthraquinone ( senna and cascara)10)Inhalational antigen stimulation leading to antibodyrecovery from vaginal mucosa of experimental animalHow It is called Dissemination of Immunologic Memory and it is thesame mechanism used in Adenovirus Vaccine The adenovirus vaccine used by the military against adenovirus types 4and 7 is an enteric-coated live non-attenuated virus preparation This vaccine produces an asymptomatic intestinal infection and therebyinduces mucosal IgA memory cells These cells then populate the mucosal immune system throughout thebody ( Because Memory cells tend to home in a tissue-specific fashion presumably returning to the type of tissue in which they first

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encountered antigen)Vaccine recipients are thus protected against adenovirus acquired byaerosol which could otherwise produce pneumonia

11)x-ray foot with calcification parallel to firstmetatarsal with decreased dorsalis pedis myositis ossificens12)Ligament that holds tibia from goin back ant and posterior cruciateligments--- that holds tibia from going back is Posterior crusiate ligament -----ligament that prevents tibia from coming forward is Anterior cruciateligament13)Obturator nerve section effects obtutaror nerve injury leads to lossof adduction of thigh14)Pelvic ascites site of drainage on standing position the site ofdrainage is vescicouteric pouch in females and rectovescical poch inmales15)Aortic aneurysm rupture effect on urinalysis in thebackground of anuria aortic aneurysm leads to renal infarctionso therewill rbc in urine16)Hand decreased sensation lateral aspect median nerve injury17)Hand sensation ok but extention ofmetacarpophalangeal joints difficult exention and flexion are done bylumbricals and interossis muscles the extension at MP joint by---gtextensors of the fingersflexion at MP joint by---gtlumbricals and introssei so if extension isdifficult means extensors are weakwhich are supplied by radialnerve

18)Clubbing description choices bronchiectasis asthma clubbing isseen in bronchiectasis

Q1) Cystic fibrosis heterozygous frequency Q2) Chemotherapy heart failure acirceuroldquo left heartrightheartmyocardial fibrosis Maybe Doxorubicin (Adriamycin) FA p330 orDaunorubicin But have no idea what is the mechanismQ3) Stimulants and inhibitors of pancreatic secretionsexocrine and endocrine Exocrine- Stimulants CCK Secretin parasympathetics Inhibitors None Endocrine- Insulin Stimulants Glucose Amino Acid GIP Glucagon Insulin Inhibitors Somatostatin Sympathetics (Alpha) Glucagon Stimulants Amino acid Glucagon Inhibitors Insulin Somatostatin

Q4) Cellular barrier between gall bladder cavity andwallacirceurotrades epithelial cells is maybe asking for Tight junction Tightjunction must be there to protect the internal celluar structures fromnasty bileQ5) Embryology neural tube formation cellular dnafragmentation indicates Apoptosis Q6) War veteran describing killing business like acirceuroldquo defence mech

Q7) Trigeminal nerve nucleus identification in medulla ct cross section(you can just say verbally where its located) Q8) Efferent renal constriction effects on GFR ampFiltration fraction GFR amp FF both increasesQ9)Premature birth surfactant and steroid therapy fails due to surfacetension increasedecrease etc Q10) Barret esophageal cancer type Adenocarcinoma since barrettsis Metaplasia full of intesinal cellsQ11)GERD cuz of secretions from which type of gastric cells BRS Physiology(p223) says that the relaxaton of loweresophageal sphincter is vagally mediated and the neurotransmitter isVIP Or maybe GERD could be due to gastric acid therefore parietal cellcould be an answerQ12) Cholecystectomy patients absorb fat from Cholecystectomy ptwill still absorbing fat from terminal ileum I think well ofcourse fromsmall intestine cholecystectomy has nothing to do with the site ofabsorbtion the person still produces bile( in liver) just no storage or conecentrationof bile thats why post op cholecystectomy patients are put on low fatdiet

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but site of absorbtion remains small intestine (ileum) as usual

Q13)Sputum silver staining for bugs silver staining reminds me of twobugsbut I am not sure Pneumocysyis carinii Legionella pneumoniaeBut silver staining of PCP is done on pts Bronchoalveolar lavage IguessQ14) First thing to say to dad patient brought by 2daughters who express wish to remain with patientBest statement to make to build rapport with patientplaying crossword on encounter May be Doctor have to ask the ptwhether he wants their daughter in the room while interviewingQ15) Post break-up with boyfriend mother of patient finds synthroidtablets in nursing student daughteracirceurotrades belongings Docacirceurotrades responseto patient synthyroid is Thyroid hormone I guess but not sure if it isT3 or T4 the pt may be planning on weight loss because boyfriendhated her obesity q16)Fragile X family parents concern regarding testing of normal 14-year daughteracirceurotrades genome for similar problems Q 17) Girl child dumps classes since uncleacirceurotrades death and mother findsit helpful for daughter to be around home Intervention requiredFamily therapypsychotherapyacirceurobrvbaretc Q18) Porphyrias like the back of ur hands q19) Carbon tetrachloride how it affects liver CCl4 - The liver convertsCCl4 to a CCl3 free radical which damages the liver (fulminanthepatitis fatty change) from Goljans STARS pathology review p93

Acyclovir mechanism of action inhibhits DNA viral poymerase andphosphorylated by viral thymidine kinaseQ20) Hernia above n lateral to pubis Hernia above the inguinal lig isInguinal hernia and below the lig is femoral hernia So it could beboth Indirect and direct inguinal hernia since it doesnt say anythingabout hernias relation to inf epigastric vesselsQ21)Hydatidiform mole learn how to interpret genotypes of moles

Which 2 Joints are Never affected in RA Distal interphalangeal and theBack joints r never involved in RAQ1) Best means of bringing down temperature of seizingpatient with meningitis pharmacologic and otherwise think nonpharamacologic tt shd be hydrotherapy to bring down tempnpharamacologic may be paracetamol by rectal routeQ2) Acetaminophen overdose how it damages In overdose the storesof GSH are depleted and and the metabolite N-acetylbenzoquinoneiminereacts with hepatocytes leading to liver necrosis Acetaminophen formsfree radicals in the liver and results in fulminant hepatitis renalpapillary necrosisdamages by free radicals which r removed by glutathioneNACETYLCYSTEIN its antidote restores the glutathione levelsQ3) Antimicrosomal antibodies involved in hashimotos autoimmunethyroiditis and autoimmune hepatitisQ4)Dialysis patient on transplant list gets angry often and missesdialysis appointments - intervention need to spend more time withpatientdiscuss regardingreconsideration of transplant listacirceurobrvbaretc Dialysis patient on transplantlist gets angry often and misses dialysis appointments - interventionneed to spend more time with patientdiscuss regarding reconsiderationof transplant listacirceurobrvbaretc need to spend more time with patient toknow what exactly is his probQ5) Adenovirus acirceuroldquo structure nonenvelopedds linear DNA icosahedralnucleocapsid only virus with a fibre protruding from each of 12 verticesof teh capsidQ6) Brown fat of neonates Function site of heat production in aneonate---brown adipose tissue contain natural uncoupling proteinwhich allows energy loss in the form of heat to maintain basal tempQ7) Longterm steroid use effect on adrenals adrenal suppressiontherefore tapered slowly neg feed back on ant pit so decreased ACTHso less stim of adrenalsacirceurobrvbarhypothalamo pituitary axis and eventuallyleads to atrophy of the adrenal glandQ8) Trypanosome cruzi life cycle try cruzi lifecycle involves reduvidbud as a vector and both humans and animals as reservoirs life cycleacirceurobrvbar reservoirs are cats dogsacirceurobrvbar reduviid bug passes the trypomastigoteas it bites and scratching implants in bite siteacirceurobrvbaracirceurobrvbaracirceurobrvbarreservoir isrodents armadillos vector is reduviid bug it transmits the trypo-mastigote form which turns into the amastigote form inside the body Atthe bite site the lseion is called chagoma Systemic symptoms are

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fever lymphadenopathy Tachycardia meningoencephalitis Thencomes the intermediate phase where the patient is asymptomatic withlow levels of the parasite and antibodies against it decades later-thechronic form emerges with dilated cardiomyopathy megacolonmegaesophagusTreatment is NifurtimoxQ9)Patient requiring dialysis says donacirceurotradet want machines to keep mealive Docacirceurotrades next step Q10)Antifungals big time Drug interactions Mechanism of actions(letswrite few antifungals with mech of action and main side effectswe willnever forget it if we do so) amphotericin B binds ergosterol creates poresflucytosine-inhibit thymidilate synthaseazole-inhibit ergosterol synthesisgriesofulvin-interfere with microtubule functionterbinafine- inhibit squalene epoxideDRUG INERACTIONSAZOLE GRP INCREASE TOXICITY OF FOLL BY INHIBITING ITSMETABOLISMbdzcisapridecyclosporinefluoxetinelovastatinomeprazoleQ11) Alcoholic with nosebleed Wot to expect in terms of AST PT andforgotacirceurobrvbar( I dont know exactly whats being askedlets see who figuresit out) AST is increased platelet count is decreased prolonged PTQ12)Picture of normal hand and a slender hand shown and asked fordiagnosis Q13)Wernicke mammillary body identification on CT( here just name thestructures affected in wernickes encephalopathy and ofcourse do knowhow to identify themvery very HY) mammillary bodies anddorsomedial nucleus of thalamusacirceurobrvbarMamillary bodies on the ventralsurface of the brain stemQ14) How HBV causes liver cancer HBV DNA integrates in hostgenomic DNAMODIFICATIONOF GENE EXPRESSION HBVINCORPORATES itself into the hepatocyte dna and triggers malignantgrowth theres is a 200 X Risk of developing HCC in carriers versusnoncarriersQ15)Patient taking OCP Smoker Wot u wanna check first smokinginduces met enzymes increased metabolism of OCPSdecreased efficacySmoking itself is thrombogenic and estrogen also isacirceurobrvbar ask for historyof thrombosis may be check PT PTTQ16)Allopurinol acirceuroldquo effect on renal stones It inhibits xanthine oxidasedecreasing uric acidallopurinol used in pts of renal stones as calcium oxalate stone formersare hyperuricemicQ17)Radiation alopecia acirceuroldquo dermal histopathology sparse mixeddermal inflammatory infiltrate consisting mainly of lymphocytes Mucinous deposits confirmed by alcian bluePAS stain were observedwithin the epidermis of the hair follicleQ18)Streptococcus pyogenes acirceuroldquo patient penicillin allergicNext step Can give Clavulanic acid Sulbactam TazobactamCephalosporins should be avoided in patients allergic to penicillinbecause of cross sensitivity Cephalosporins are susceptible to betalactamase but less than penicillin penicillin allergic pts erythromycinor azithromycin are the alternatives all GRP A Streptoccoci r susceptibleto pencillin G but neither Rhematic fever nor allergic pats benefit frompencillin treatment after onset In pencillin allergies pats should geterythromycin or azithromycinHOWEVER ENTEROCOCCAL ENDOCARDITIS CAN BE ERADICATED ONLYBY PENICILLIN OR VANCOMYCIN COMBINED WITH ANAMINOGLYCOSIDEQ19)t-Rna triplet codon function The anti codon on the tRNA pairs withthe codon for aa in mRNA Q20) Nuclear membrane acirceuroldquo evolutionary importance betweeneukaryotes and prokaryotes all I know is nucleus membrane is absentin prokaryotes and present in euk may be evolutionary imp is to protectthe genetic information

there are 4 trigeminal nuclei---gt1)primary sensory nuclei for sensations of face2)spinal trigeminal nucleus for pain and tempreature sensation of face3)Mesencepahalic nucleus for proprioception4)primary motor nucleus for muscles of mastication

ZEBRA genesZ EBV replication activator (ZEBRA) as lytic cycle

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markersZEBRA is one of the immediate early genes of EBVit isconsidered to be expressed in the initial stage of the lytic cycle beforethe viral particles have been dispersed Zebra sign Hemorrhage is often characterized by a typical streakybleeding pattern due to blood spreading in the cerebellar sulci thiszebra-pattern hemorrhage seems to be typical in a postoperative lossof CSF Zebra bodies - lipid inclusions with concentric lamellar structure withalternating light and dark-staining bands in neuronal cells in neimannpicks Zebra tumor = acoustic neuromaQ1)Lead poisoning( symptoms) --Lead poisoningacirceurobrvbar lead inhibitsferrochelatase and ALA dehydraseacirceurobrvbar coproporhyrin and ALAaccumulate in urine sympacirceurordquoabdominal colic sideroblastic anemiawrist and foot drop lead lines in gingivae and epiphysis of long bonesencephalopathy basophilic stipplingQ2) Glutamine in urea cycle Q3) Large intestine gross section tumor shown Type(felt like the napkin constriction)I never heard of this kind oftumoranyone knows Q4) Radiation therapy pelvis Cause for urinary retention cystitsfibrosisQ5) Osteogenesis imperfecta defect d AD mutation in collagen genesQ6) Medial side of arm numbness after mastectomy nerve involvedintercostobrachial n also known as the lateral cutaneous br of theventral primary ramus of T2Q7) Interleukins big time Learn function of eachwe can namesomeand functionIL1- stim produced mainly by macrophages IL2 syn pyrogenic activates TH IL2- downreg TH2 Tcell growthfactor stim BcellIL3- stim BM stem cellsIL4-class switch to IgEIL5-Class swish to eosinophil promote B cell prolifIL6- produc of acute phase reactantsIL8-chemotactic and adhesion of neutrophilsIL10-Inhibit TH1 inhibit cytokine from macrophageIL12-induce TH0 to TH1Q8) Plummer Vinson esophageal defect Esophageal websacirceurobrvbar irondeficiency anemia o Stomatitis o Glossitis o Dysphagia o Spoon-shaped nails o Esophageal webs

Q9)Scurvy enzymereaction involved Prolyl and lysyl hydroxylase theenzymes that catalyzes the hydroxylation require vitamin CQ10)Reiter syndrome vs Sjogren Reiter syndrome--- urethritis conjunctivitis and ant uveitis arthritisSjogrenXerophthalmia xerostomia arthritis parotid enlargementQ11)Managing hypertensive crisis in MAO inhibitor patient on cheeseitacirceurotrades pathogenesis Treatment ot a Hypertensive Crisis from MAOIReactionThis is a medical emergency with cerebral vascular accidents being oneof the greatest concerns Medical consultation is warranted Patientsshould report to an immediately to an emergency department Initialtreatment options include Phentolamine 5 mg IV or Thorazine 50 to 100 mg po Care should be taken to ensure that the patient does not becomedangerously hypotensive or that the hypertensive state returns once theintervention medication has worn off Tyramine is actively transportedinto neurons and displaces NE leading to intraneuronal release of NEIt can be degraded by MAO but if you are on MAOI its interaction willcause tyramine build up Tons of NE will be replaced and hence theHTN crisisQ12) Neurotransmitter involved in Huntington Decreased GABA andAChQ13)Aortic coarctation site of constriction and symptoms infantile typeis preductal Cardiomegaly Pulmonary venous congestion RightVentricular HypertrophyAdult is postductal asso with notching of ribs Displaced esophagealshadow rightward Left Ventricular Hypertrophy HT in UL weak pulsesin LL

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Q14) Chronic antiplatelet drug in aspirin sensitive Clopidogrel ampTiclopidine They are back-up or alternative drugs to aspirin Theyblock ADP receptors on platelets hence decrease activationQ15)Stroke patient getting MI treated with streptokinasedies due to cva Cause concluded that death of the patient occurreddue to rebleeding on administration of streptokinase 1 IntracranialHemorrhage As PRS has mentioned the death could be due to intracranialhemorrhage Since CVA refers to both ischemic (80) andhemorrhagic(20)This is more likely than other explanation to me

2 Therapeutic Failure It could be due to strptokinases property itselfSince most individuals have had a streptococcal infection sometime intheir lives circulating antibodies against streptokinase are likely to bepresent in most patients These antibodies can combine withstreptokinase and neutralize its fibrinolytic properties (Therapeuticfailure)(lippincott Pharmacology 2nd edition p203) 3 Property of all Thrombolytic agents As the thrombolytic agents dissolute clot Increased local thrombinmay occur as the clot dissolves leading to enhanced plateletaggregability and thrombosis Strategies to prevent this includeadministration of antiplatelet drugs such as aspirin orantithrombotics such as heparin

Drugs that have been implicated in the development of serum sickness-like reactions include the following allopurinol (Zyloprim) arsenicalsand mercurial derivatives barbiturates captopril (Capoten)cephalosporins furazolidone (Furoxone) gold salts griseofulvin(Fulvicin Grifulvin) halothane hydralazine (Apresoline) iodidesmethyldopa para-aminosalicylic acid penicillamine penicillinsphenytoin (Dilantin) piperazine procainamide (Procan SR ProcanbidPronestyl-SR) quinidine (Quinaglute Quinalan Quinidex Quinora)streptokinase (Streptase Kabikinase) sulfonamides and thiouracils

Q16)Leukotriene inhibitors ZafirlukastacirceurobrvbarLT receptor antagonistQ17) Chromolyn sodium Mechanism of action prevent degranulation ofmast cellsQ18)Graveacirceurotrades pathophysiology autoimmune TSH receptor antibodiestype II hypersensitivityQ19) Couple in for infertility counseling High BMI Wifesays acirceuroœit kills me not to be able to have a babyacirceuroDocacirceurotrades best response obese wife possibly has Polycystic OvarianSyndrome (PCOS)74 of PCOS pt has infertility and PCOS accounts for 30 of overallinfertilityTherefore the doctor may have to evaluate for PCOS by Lab bloodtest and Ultrasonography The lab blood test will show Increasedandrogen LH fasting insulin prolactin and estrogens Theultrasonography is the most sensitive diagnostic study If the Dx of PCOS have been confirmed Tx should be Weightreduction quit smoking and antiandrogen(because of hirsutism) andantiestrogen(clomiphen)

Q20)Baby awakens at night frightened goes back to sleepDoes not respond to questions b parents on that awakening Best nextstep The boy is possibly having Night Terrors It occurs in Delta sleep so you cant wake them and they cant remember what happened Andnight terror is shown to be precursor to temporal lobe epilepsyThe doctors response should be either examine for any epilepsy in the pt(prevent or tx the temporal lobeepilepsy) or Identify amp dealing with waking-time anxiety to relieve night terrorsceliac disease is the proximal bowel and tropical sprue involves the entire bowel

Q1) Prematue ejaculation Best next step Ans- selective seratononreuptake inhibhitors like fluoxetine or even clorpramine (which is themost seratonin specific hetrocyclics)Q2)Delirium big time ( just define) Ans-Impaired conciousness(incontrast to dementia which is loss of

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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raising5 Arteriogram of ACA pt with lower exteremity paralysis6 MRI of spine shown pt cant feel pain and temp on lowerexteremites7 Esophageal veins initiates from what vein8 Gag reflex9 Thymus anatomical location between manubrium and hyoid bone10 1st part of doudinum fed by what artery11 loss of dorsiflexion what nerve12 what artery supplies testicles where does it comes from13 what nerve supplies anal area14 Histologic pic shown Dx Diabetic GN15 IgA def pulmonary problems Dx16 Described skin infection DXHZV17 Arrest of ovum prophase I18 40 yo undecended testes his spermatogonia is in what phasehaploid diploid n 2n19 Odd ratio just simply know the formula20 Beta error 1-B 90 (dont recall the whole thing

21 Case control study retrospective22 Describe specifity23 eyes can not do lateral gase but looking down and up is ok Whatnerve damaged24 pt can not look medially what nerve damaged25 Renal cell carcinomavit D26 Thyroxine T4 activates what receptor eg thyrosine kinase27 Steroid receptors28 PDAcyanosiscontinious murmur at the ApexgtL hrthyperthpy29 Older pt calcification of valves vegitation30 Heme synthesis option was Succinyl CoA

PX with signs amp symptoms of goodpasture what would lm show onbiopsycresentphoto of plasma cella pt with lytic lesion vertebra wat diseasewat drug usually given pretreatment for leukemiamoa of doxurubicinmoa abacavir(ans reverse transcriptase inhibitor)ho pt having gynecomastia labast alt incans ketoconazola Diag exactlly 4m frst aid ans chancrestaright qs abt BPHASKING qs abt endometriosispedigree of mito inheritancecleft lip failure of watcase of alcholic hepatitisho UMN lesion identify the lesion MRICASE SENSITIVITY AND SPECIFICITYpt having wt lose some psychtic symptom dilated pupil asking abt drugabuset

31 Rate limiting step in heme synthesisacirceurobrvbarALA32 steatoureaacirceurobrvbarbc of HMG-CoA reductase33 what is increased in lack of HMG-CoA reductaseTriglycerides Chylomicrons34 pt Macrocytic neurological defacirceurobrvbargtB12 def35 pt with gastritis fundus region anti-bodyagainst IFacirceurobrvbarwhat will be deficient36 B12 def acirceurobrvbarterminal illium37 Described Chronacirceurotrades dizacirceurobrvbarasked lesions are whereJujunium with bloody diarrhea38 Rhumatiod arthritis39 Pic of swallen finger Septic arthritis40 pic of small petichia on skinacirceurobrvbarwhat is def vit Cdef

PT in hot sun gets red on her faceacirceurobrvbarbc of Options Melanocytes-ADA deficient what cumulates Options Adenineuric acid urea- MOA Colchicine- pt has low O2 satacirceurobrvbar 75 bc of options 23BPG

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decreasedacirceurobrvbar- acirceurotrades given DM1 ketoacidosis MetabolicAlkolysis and acidosis- post-op 7 days MRI shownacirceurobrvbaroption PE- UTI older pt no Ecoli in the optionsacirceurobrvbarbut G-diplocco- Picnic meat watery diaacirceurobrvbarwhat bug Optionscamplobacter juju strep saphraticus c basillus - Pt With bloody diarrhea what bug - umbilical vein or artery thrombus to wherecauses cerebral infarct why Options open foramensecondum- VQ mismatch options perfusion decreased atapex or higher O2

acirceurobrvbarKNOW ENDOCRINE PHYSIOLOGY AND PATHOPHYSIOLOGY acirceurobrvbaracirceurobrvbar Know your vitamins very wellImmuno-know all the cytokines neuro - know the cerebral cortex very wellall the areas-brocaswernickes etcmany questions on spinal cord segmentsmost of the neuro questionswere based on imagesa nurse use iodine before giving insulin why--to sterlize that areafrom virusbacteria and fungi a girl has 28 days cyclephyscian do her hormone teston the day26 what hormone will be increase ---option are FSHLHTSHHCG MAKE SURE HOW TO READ CT SCANS AND MRIS THE ANATOMYQUESTIONS HAD ALOT OF CT SCANS SHOWING VARIOUS MUSCLESLike for example some person had a superior gluteal nerve lesion andit had a CT scan of the pelvis and you had to identify the MUSCLEAlso 2 QUESTIONS ON EPIDURAL HEMATOMA ASKED WHICH ARTERYIS DAMAGED FETAL ALCOHOL SYNDROME KNOW THE SIGNS (DONT GETCONFUSED WITH DOWNS SYNDROME)HYPERHYPO THYROIDISM

1)Pituitary tumor on visual fields PITUTARY TUMOUR ISCRANIOPHRANGIOMA CAUSES BITEMPORAL HEMIANOPSIA

2)Tumor anterior to temporal fossa affects wot 3)Tends to fall to one side tongue deviates to othersite of lesion THIS is problem in 12 cranial nerve which is locted inlower medulla4)Pediatric infratentorial tumor most of the paediatric tumours areinfra tentorialthey are celleblarastrocytoma2medulloblastoma3gliomas

5)Midline neck mass at level of hyoid BRANCHIAL CYST

6)Esophagal hiatus of diaphragm IT OPENS AT THE LEVEL OF T10 IVChiatus at T8descending aorta opening at T12

7)Splenic venous drainage VENOUS SINUSOIDS IN CORDS OFBILROTH8)Ambiguous genitalia AMBIGOUS GENITIAL is in female with excessof testosterone or in male with lack of testorone

9)Melanosis coli MELONOSIS COLI I is due over use of laxativescolonappers black in colour Melanosis coli is due to use of laxatives notantibiotics Usually anthraquinone ( senna and cascara)10)Inhalational antigen stimulation leading to antibodyrecovery from vaginal mucosa of experimental animalHow It is called Dissemination of Immunologic Memory and it is thesame mechanism used in Adenovirus Vaccine The adenovirus vaccine used by the military against adenovirus types 4and 7 is an enteric-coated live non-attenuated virus preparation This vaccine produces an asymptomatic intestinal infection and therebyinduces mucosal IgA memory cells These cells then populate the mucosal immune system throughout thebody ( Because Memory cells tend to home in a tissue-specific fashion presumably returning to the type of tissue in which they first

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encountered antigen)Vaccine recipients are thus protected against adenovirus acquired byaerosol which could otherwise produce pneumonia

11)x-ray foot with calcification parallel to firstmetatarsal with decreased dorsalis pedis myositis ossificens12)Ligament that holds tibia from goin back ant and posterior cruciateligments--- that holds tibia from going back is Posterior crusiate ligament -----ligament that prevents tibia from coming forward is Anterior cruciateligament13)Obturator nerve section effects obtutaror nerve injury leads to lossof adduction of thigh14)Pelvic ascites site of drainage on standing position the site ofdrainage is vescicouteric pouch in females and rectovescical poch inmales15)Aortic aneurysm rupture effect on urinalysis in thebackground of anuria aortic aneurysm leads to renal infarctionso therewill rbc in urine16)Hand decreased sensation lateral aspect median nerve injury17)Hand sensation ok but extention ofmetacarpophalangeal joints difficult exention and flexion are done bylumbricals and interossis muscles the extension at MP joint by---gtextensors of the fingersflexion at MP joint by---gtlumbricals and introssei so if extension isdifficult means extensors are weakwhich are supplied by radialnerve

18)Clubbing description choices bronchiectasis asthma clubbing isseen in bronchiectasis

Q1) Cystic fibrosis heterozygous frequency Q2) Chemotherapy heart failure acirceuroldquo left heartrightheartmyocardial fibrosis Maybe Doxorubicin (Adriamycin) FA p330 orDaunorubicin But have no idea what is the mechanismQ3) Stimulants and inhibitors of pancreatic secretionsexocrine and endocrine Exocrine- Stimulants CCK Secretin parasympathetics Inhibitors None Endocrine- Insulin Stimulants Glucose Amino Acid GIP Glucagon Insulin Inhibitors Somatostatin Sympathetics (Alpha) Glucagon Stimulants Amino acid Glucagon Inhibitors Insulin Somatostatin

Q4) Cellular barrier between gall bladder cavity andwallacirceurotrades epithelial cells is maybe asking for Tight junction Tightjunction must be there to protect the internal celluar structures fromnasty bileQ5) Embryology neural tube formation cellular dnafragmentation indicates Apoptosis Q6) War veteran describing killing business like acirceuroldquo defence mech

Q7) Trigeminal nerve nucleus identification in medulla ct cross section(you can just say verbally where its located) Q8) Efferent renal constriction effects on GFR ampFiltration fraction GFR amp FF both increasesQ9)Premature birth surfactant and steroid therapy fails due to surfacetension increasedecrease etc Q10) Barret esophageal cancer type Adenocarcinoma since barrettsis Metaplasia full of intesinal cellsQ11)GERD cuz of secretions from which type of gastric cells BRS Physiology(p223) says that the relaxaton of loweresophageal sphincter is vagally mediated and the neurotransmitter isVIP Or maybe GERD could be due to gastric acid therefore parietal cellcould be an answerQ12) Cholecystectomy patients absorb fat from Cholecystectomy ptwill still absorbing fat from terminal ileum I think well ofcourse fromsmall intestine cholecystectomy has nothing to do with the site ofabsorbtion the person still produces bile( in liver) just no storage or conecentrationof bile thats why post op cholecystectomy patients are put on low fatdiet

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but site of absorbtion remains small intestine (ileum) as usual

Q13)Sputum silver staining for bugs silver staining reminds me of twobugsbut I am not sure Pneumocysyis carinii Legionella pneumoniaeBut silver staining of PCP is done on pts Bronchoalveolar lavage IguessQ14) First thing to say to dad patient brought by 2daughters who express wish to remain with patientBest statement to make to build rapport with patientplaying crossword on encounter May be Doctor have to ask the ptwhether he wants their daughter in the room while interviewingQ15) Post break-up with boyfriend mother of patient finds synthroidtablets in nursing student daughteracirceurotrades belongings Docacirceurotrades responseto patient synthyroid is Thyroid hormone I guess but not sure if it isT3 or T4 the pt may be planning on weight loss because boyfriendhated her obesity q16)Fragile X family parents concern regarding testing of normal 14-year daughteracirceurotrades genome for similar problems Q 17) Girl child dumps classes since uncleacirceurotrades death and mother findsit helpful for daughter to be around home Intervention requiredFamily therapypsychotherapyacirceurobrvbaretc Q18) Porphyrias like the back of ur hands q19) Carbon tetrachloride how it affects liver CCl4 - The liver convertsCCl4 to a CCl3 free radical which damages the liver (fulminanthepatitis fatty change) from Goljans STARS pathology review p93

Acyclovir mechanism of action inhibhits DNA viral poymerase andphosphorylated by viral thymidine kinaseQ20) Hernia above n lateral to pubis Hernia above the inguinal lig isInguinal hernia and below the lig is femoral hernia So it could beboth Indirect and direct inguinal hernia since it doesnt say anythingabout hernias relation to inf epigastric vesselsQ21)Hydatidiform mole learn how to interpret genotypes of moles

Which 2 Joints are Never affected in RA Distal interphalangeal and theBack joints r never involved in RAQ1) Best means of bringing down temperature of seizingpatient with meningitis pharmacologic and otherwise think nonpharamacologic tt shd be hydrotherapy to bring down tempnpharamacologic may be paracetamol by rectal routeQ2) Acetaminophen overdose how it damages In overdose the storesof GSH are depleted and and the metabolite N-acetylbenzoquinoneiminereacts with hepatocytes leading to liver necrosis Acetaminophen formsfree radicals in the liver and results in fulminant hepatitis renalpapillary necrosisdamages by free radicals which r removed by glutathioneNACETYLCYSTEIN its antidote restores the glutathione levelsQ3) Antimicrosomal antibodies involved in hashimotos autoimmunethyroiditis and autoimmune hepatitisQ4)Dialysis patient on transplant list gets angry often and missesdialysis appointments - intervention need to spend more time withpatientdiscuss regardingreconsideration of transplant listacirceurobrvbaretc Dialysis patient on transplantlist gets angry often and misses dialysis appointments - interventionneed to spend more time with patientdiscuss regarding reconsiderationof transplant listacirceurobrvbaretc need to spend more time with patient toknow what exactly is his probQ5) Adenovirus acirceuroldquo structure nonenvelopedds linear DNA icosahedralnucleocapsid only virus with a fibre protruding from each of 12 verticesof teh capsidQ6) Brown fat of neonates Function site of heat production in aneonate---brown adipose tissue contain natural uncoupling proteinwhich allows energy loss in the form of heat to maintain basal tempQ7) Longterm steroid use effect on adrenals adrenal suppressiontherefore tapered slowly neg feed back on ant pit so decreased ACTHso less stim of adrenalsacirceurobrvbarhypothalamo pituitary axis and eventuallyleads to atrophy of the adrenal glandQ8) Trypanosome cruzi life cycle try cruzi lifecycle involves reduvidbud as a vector and both humans and animals as reservoirs life cycleacirceurobrvbar reservoirs are cats dogsacirceurobrvbar reduviid bug passes the trypomastigoteas it bites and scratching implants in bite siteacirceurobrvbaracirceurobrvbaracirceurobrvbarreservoir isrodents armadillos vector is reduviid bug it transmits the trypo-mastigote form which turns into the amastigote form inside the body Atthe bite site the lseion is called chagoma Systemic symptoms are

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fever lymphadenopathy Tachycardia meningoencephalitis Thencomes the intermediate phase where the patient is asymptomatic withlow levels of the parasite and antibodies against it decades later-thechronic form emerges with dilated cardiomyopathy megacolonmegaesophagusTreatment is NifurtimoxQ9)Patient requiring dialysis says donacirceurotradet want machines to keep mealive Docacirceurotrades next step Q10)Antifungals big time Drug interactions Mechanism of actions(letswrite few antifungals with mech of action and main side effectswe willnever forget it if we do so) amphotericin B binds ergosterol creates poresflucytosine-inhibit thymidilate synthaseazole-inhibit ergosterol synthesisgriesofulvin-interfere with microtubule functionterbinafine- inhibit squalene epoxideDRUG INERACTIONSAZOLE GRP INCREASE TOXICITY OF FOLL BY INHIBITING ITSMETABOLISMbdzcisapridecyclosporinefluoxetinelovastatinomeprazoleQ11) Alcoholic with nosebleed Wot to expect in terms of AST PT andforgotacirceurobrvbar( I dont know exactly whats being askedlets see who figuresit out) AST is increased platelet count is decreased prolonged PTQ12)Picture of normal hand and a slender hand shown and asked fordiagnosis Q13)Wernicke mammillary body identification on CT( here just name thestructures affected in wernickes encephalopathy and ofcourse do knowhow to identify themvery very HY) mammillary bodies anddorsomedial nucleus of thalamusacirceurobrvbarMamillary bodies on the ventralsurface of the brain stemQ14) How HBV causes liver cancer HBV DNA integrates in hostgenomic DNAMODIFICATIONOF GENE EXPRESSION HBVINCORPORATES itself into the hepatocyte dna and triggers malignantgrowth theres is a 200 X Risk of developing HCC in carriers versusnoncarriersQ15)Patient taking OCP Smoker Wot u wanna check first smokinginduces met enzymes increased metabolism of OCPSdecreased efficacySmoking itself is thrombogenic and estrogen also isacirceurobrvbar ask for historyof thrombosis may be check PT PTTQ16)Allopurinol acirceuroldquo effect on renal stones It inhibits xanthine oxidasedecreasing uric acidallopurinol used in pts of renal stones as calcium oxalate stone formersare hyperuricemicQ17)Radiation alopecia acirceuroldquo dermal histopathology sparse mixeddermal inflammatory infiltrate consisting mainly of lymphocytes Mucinous deposits confirmed by alcian bluePAS stain were observedwithin the epidermis of the hair follicleQ18)Streptococcus pyogenes acirceuroldquo patient penicillin allergicNext step Can give Clavulanic acid Sulbactam TazobactamCephalosporins should be avoided in patients allergic to penicillinbecause of cross sensitivity Cephalosporins are susceptible to betalactamase but less than penicillin penicillin allergic pts erythromycinor azithromycin are the alternatives all GRP A Streptoccoci r susceptibleto pencillin G but neither Rhematic fever nor allergic pats benefit frompencillin treatment after onset In pencillin allergies pats should geterythromycin or azithromycinHOWEVER ENTEROCOCCAL ENDOCARDITIS CAN BE ERADICATED ONLYBY PENICILLIN OR VANCOMYCIN COMBINED WITH ANAMINOGLYCOSIDEQ19)t-Rna triplet codon function The anti codon on the tRNA pairs withthe codon for aa in mRNA Q20) Nuclear membrane acirceuroldquo evolutionary importance betweeneukaryotes and prokaryotes all I know is nucleus membrane is absentin prokaryotes and present in euk may be evolutionary imp is to protectthe genetic information

there are 4 trigeminal nuclei---gt1)primary sensory nuclei for sensations of face2)spinal trigeminal nucleus for pain and tempreature sensation of face3)Mesencepahalic nucleus for proprioception4)primary motor nucleus for muscles of mastication

ZEBRA genesZ EBV replication activator (ZEBRA) as lytic cycle

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markersZEBRA is one of the immediate early genes of EBVit isconsidered to be expressed in the initial stage of the lytic cycle beforethe viral particles have been dispersed Zebra sign Hemorrhage is often characterized by a typical streakybleeding pattern due to blood spreading in the cerebellar sulci thiszebra-pattern hemorrhage seems to be typical in a postoperative lossof CSF Zebra bodies - lipid inclusions with concentric lamellar structure withalternating light and dark-staining bands in neuronal cells in neimannpicks Zebra tumor = acoustic neuromaQ1)Lead poisoning( symptoms) --Lead poisoningacirceurobrvbar lead inhibitsferrochelatase and ALA dehydraseacirceurobrvbar coproporhyrin and ALAaccumulate in urine sympacirceurordquoabdominal colic sideroblastic anemiawrist and foot drop lead lines in gingivae and epiphysis of long bonesencephalopathy basophilic stipplingQ2) Glutamine in urea cycle Q3) Large intestine gross section tumor shown Type(felt like the napkin constriction)I never heard of this kind oftumoranyone knows Q4) Radiation therapy pelvis Cause for urinary retention cystitsfibrosisQ5) Osteogenesis imperfecta defect d AD mutation in collagen genesQ6) Medial side of arm numbness after mastectomy nerve involvedintercostobrachial n also known as the lateral cutaneous br of theventral primary ramus of T2Q7) Interleukins big time Learn function of eachwe can namesomeand functionIL1- stim produced mainly by macrophages IL2 syn pyrogenic activates TH IL2- downreg TH2 Tcell growthfactor stim BcellIL3- stim BM stem cellsIL4-class switch to IgEIL5-Class swish to eosinophil promote B cell prolifIL6- produc of acute phase reactantsIL8-chemotactic and adhesion of neutrophilsIL10-Inhibit TH1 inhibit cytokine from macrophageIL12-induce TH0 to TH1Q8) Plummer Vinson esophageal defect Esophageal websacirceurobrvbar irondeficiency anemia o Stomatitis o Glossitis o Dysphagia o Spoon-shaped nails o Esophageal webs

Q9)Scurvy enzymereaction involved Prolyl and lysyl hydroxylase theenzymes that catalyzes the hydroxylation require vitamin CQ10)Reiter syndrome vs Sjogren Reiter syndrome--- urethritis conjunctivitis and ant uveitis arthritisSjogrenXerophthalmia xerostomia arthritis parotid enlargementQ11)Managing hypertensive crisis in MAO inhibitor patient on cheeseitacirceurotrades pathogenesis Treatment ot a Hypertensive Crisis from MAOIReactionThis is a medical emergency with cerebral vascular accidents being oneof the greatest concerns Medical consultation is warranted Patientsshould report to an immediately to an emergency department Initialtreatment options include Phentolamine 5 mg IV or Thorazine 50 to 100 mg po Care should be taken to ensure that the patient does not becomedangerously hypotensive or that the hypertensive state returns once theintervention medication has worn off Tyramine is actively transportedinto neurons and displaces NE leading to intraneuronal release of NEIt can be degraded by MAO but if you are on MAOI its interaction willcause tyramine build up Tons of NE will be replaced and hence theHTN crisisQ12) Neurotransmitter involved in Huntington Decreased GABA andAChQ13)Aortic coarctation site of constriction and symptoms infantile typeis preductal Cardiomegaly Pulmonary venous congestion RightVentricular HypertrophyAdult is postductal asso with notching of ribs Displaced esophagealshadow rightward Left Ventricular Hypertrophy HT in UL weak pulsesin LL

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Q14) Chronic antiplatelet drug in aspirin sensitive Clopidogrel ampTiclopidine They are back-up or alternative drugs to aspirin Theyblock ADP receptors on platelets hence decrease activationQ15)Stroke patient getting MI treated with streptokinasedies due to cva Cause concluded that death of the patient occurreddue to rebleeding on administration of streptokinase 1 IntracranialHemorrhage As PRS has mentioned the death could be due to intracranialhemorrhage Since CVA refers to both ischemic (80) andhemorrhagic(20)This is more likely than other explanation to me

2 Therapeutic Failure It could be due to strptokinases property itselfSince most individuals have had a streptococcal infection sometime intheir lives circulating antibodies against streptokinase are likely to bepresent in most patients These antibodies can combine withstreptokinase and neutralize its fibrinolytic properties (Therapeuticfailure)(lippincott Pharmacology 2nd edition p203) 3 Property of all Thrombolytic agents As the thrombolytic agents dissolute clot Increased local thrombinmay occur as the clot dissolves leading to enhanced plateletaggregability and thrombosis Strategies to prevent this includeadministration of antiplatelet drugs such as aspirin orantithrombotics such as heparin

Drugs that have been implicated in the development of serum sickness-like reactions include the following allopurinol (Zyloprim) arsenicalsand mercurial derivatives barbiturates captopril (Capoten)cephalosporins furazolidone (Furoxone) gold salts griseofulvin(Fulvicin Grifulvin) halothane hydralazine (Apresoline) iodidesmethyldopa para-aminosalicylic acid penicillamine penicillinsphenytoin (Dilantin) piperazine procainamide (Procan SR ProcanbidPronestyl-SR) quinidine (Quinaglute Quinalan Quinidex Quinora)streptokinase (Streptase Kabikinase) sulfonamides and thiouracils

Q16)Leukotriene inhibitors ZafirlukastacirceurobrvbarLT receptor antagonistQ17) Chromolyn sodium Mechanism of action prevent degranulation ofmast cellsQ18)Graveacirceurotrades pathophysiology autoimmune TSH receptor antibodiestype II hypersensitivityQ19) Couple in for infertility counseling High BMI Wifesays acirceuroœit kills me not to be able to have a babyacirceuroDocacirceurotrades best response obese wife possibly has Polycystic OvarianSyndrome (PCOS)74 of PCOS pt has infertility and PCOS accounts for 30 of overallinfertilityTherefore the doctor may have to evaluate for PCOS by Lab bloodtest and Ultrasonography The lab blood test will show Increasedandrogen LH fasting insulin prolactin and estrogens Theultrasonography is the most sensitive diagnostic study If the Dx of PCOS have been confirmed Tx should be Weightreduction quit smoking and antiandrogen(because of hirsutism) andantiestrogen(clomiphen)

Q20)Baby awakens at night frightened goes back to sleepDoes not respond to questions b parents on that awakening Best nextstep The boy is possibly having Night Terrors It occurs in Delta sleep so you cant wake them and they cant remember what happened Andnight terror is shown to be precursor to temporal lobe epilepsyThe doctors response should be either examine for any epilepsy in the pt(prevent or tx the temporal lobeepilepsy) or Identify amp dealing with waking-time anxiety to relieve night terrorsceliac disease is the proximal bowel and tropical sprue involves the entire bowel

Q1) Prematue ejaculation Best next step Ans- selective seratononreuptake inhibhitors like fluoxetine or even clorpramine (which is themost seratonin specific hetrocyclics)Q2)Delirium big time ( just define) Ans-Impaired conciousness(incontrast to dementia which is loss of

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

Remembered questions for STEP 1 - USMLE Forum

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

Remembered questions for STEP 1 - USMLE Forum

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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decreasedacirceurobrvbar- acirceurotrades given DM1 ketoacidosis MetabolicAlkolysis and acidosis- post-op 7 days MRI shownacirceurobrvbaroption PE- UTI older pt no Ecoli in the optionsacirceurobrvbarbut G-diplocco- Picnic meat watery diaacirceurobrvbarwhat bug Optionscamplobacter juju strep saphraticus c basillus - Pt With bloody diarrhea what bug - umbilical vein or artery thrombus to wherecauses cerebral infarct why Options open foramensecondum- VQ mismatch options perfusion decreased atapex or higher O2

acirceurobrvbarKNOW ENDOCRINE PHYSIOLOGY AND PATHOPHYSIOLOGY acirceurobrvbaracirceurobrvbar Know your vitamins very wellImmuno-know all the cytokines neuro - know the cerebral cortex very wellall the areas-brocaswernickes etcmany questions on spinal cord segmentsmost of the neuro questionswere based on imagesa nurse use iodine before giving insulin why--to sterlize that areafrom virusbacteria and fungi a girl has 28 days cyclephyscian do her hormone teston the day26 what hormone will be increase ---option are FSHLHTSHHCG MAKE SURE HOW TO READ CT SCANS AND MRIS THE ANATOMYQUESTIONS HAD ALOT OF CT SCANS SHOWING VARIOUS MUSCLESLike for example some person had a superior gluteal nerve lesion andit had a CT scan of the pelvis and you had to identify the MUSCLEAlso 2 QUESTIONS ON EPIDURAL HEMATOMA ASKED WHICH ARTERYIS DAMAGED FETAL ALCOHOL SYNDROME KNOW THE SIGNS (DONT GETCONFUSED WITH DOWNS SYNDROME)HYPERHYPO THYROIDISM

1)Pituitary tumor on visual fields PITUTARY TUMOUR ISCRANIOPHRANGIOMA CAUSES BITEMPORAL HEMIANOPSIA

2)Tumor anterior to temporal fossa affects wot 3)Tends to fall to one side tongue deviates to othersite of lesion THIS is problem in 12 cranial nerve which is locted inlower medulla4)Pediatric infratentorial tumor most of the paediatric tumours areinfra tentorialthey are celleblarastrocytoma2medulloblastoma3gliomas

5)Midline neck mass at level of hyoid BRANCHIAL CYST

6)Esophagal hiatus of diaphragm IT OPENS AT THE LEVEL OF T10 IVChiatus at T8descending aorta opening at T12

7)Splenic venous drainage VENOUS SINUSOIDS IN CORDS OFBILROTH8)Ambiguous genitalia AMBIGOUS GENITIAL is in female with excessof testosterone or in male with lack of testorone

9)Melanosis coli MELONOSIS COLI I is due over use of laxativescolonappers black in colour Melanosis coli is due to use of laxatives notantibiotics Usually anthraquinone ( senna and cascara)10)Inhalational antigen stimulation leading to antibodyrecovery from vaginal mucosa of experimental animalHow It is called Dissemination of Immunologic Memory and it is thesame mechanism used in Adenovirus Vaccine The adenovirus vaccine used by the military against adenovirus types 4and 7 is an enteric-coated live non-attenuated virus preparation This vaccine produces an asymptomatic intestinal infection and therebyinduces mucosal IgA memory cells These cells then populate the mucosal immune system throughout thebody ( Because Memory cells tend to home in a tissue-specific fashion presumably returning to the type of tissue in which they first

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encountered antigen)Vaccine recipients are thus protected against adenovirus acquired byaerosol which could otherwise produce pneumonia

11)x-ray foot with calcification parallel to firstmetatarsal with decreased dorsalis pedis myositis ossificens12)Ligament that holds tibia from goin back ant and posterior cruciateligments--- that holds tibia from going back is Posterior crusiate ligament -----ligament that prevents tibia from coming forward is Anterior cruciateligament13)Obturator nerve section effects obtutaror nerve injury leads to lossof adduction of thigh14)Pelvic ascites site of drainage on standing position the site ofdrainage is vescicouteric pouch in females and rectovescical poch inmales15)Aortic aneurysm rupture effect on urinalysis in thebackground of anuria aortic aneurysm leads to renal infarctionso therewill rbc in urine16)Hand decreased sensation lateral aspect median nerve injury17)Hand sensation ok but extention ofmetacarpophalangeal joints difficult exention and flexion are done bylumbricals and interossis muscles the extension at MP joint by---gtextensors of the fingersflexion at MP joint by---gtlumbricals and introssei so if extension isdifficult means extensors are weakwhich are supplied by radialnerve

18)Clubbing description choices bronchiectasis asthma clubbing isseen in bronchiectasis

Q1) Cystic fibrosis heterozygous frequency Q2) Chemotherapy heart failure acirceuroldquo left heartrightheartmyocardial fibrosis Maybe Doxorubicin (Adriamycin) FA p330 orDaunorubicin But have no idea what is the mechanismQ3) Stimulants and inhibitors of pancreatic secretionsexocrine and endocrine Exocrine- Stimulants CCK Secretin parasympathetics Inhibitors None Endocrine- Insulin Stimulants Glucose Amino Acid GIP Glucagon Insulin Inhibitors Somatostatin Sympathetics (Alpha) Glucagon Stimulants Amino acid Glucagon Inhibitors Insulin Somatostatin

Q4) Cellular barrier between gall bladder cavity andwallacirceurotrades epithelial cells is maybe asking for Tight junction Tightjunction must be there to protect the internal celluar structures fromnasty bileQ5) Embryology neural tube formation cellular dnafragmentation indicates Apoptosis Q6) War veteran describing killing business like acirceuroldquo defence mech

Q7) Trigeminal nerve nucleus identification in medulla ct cross section(you can just say verbally where its located) Q8) Efferent renal constriction effects on GFR ampFiltration fraction GFR amp FF both increasesQ9)Premature birth surfactant and steroid therapy fails due to surfacetension increasedecrease etc Q10) Barret esophageal cancer type Adenocarcinoma since barrettsis Metaplasia full of intesinal cellsQ11)GERD cuz of secretions from which type of gastric cells BRS Physiology(p223) says that the relaxaton of loweresophageal sphincter is vagally mediated and the neurotransmitter isVIP Or maybe GERD could be due to gastric acid therefore parietal cellcould be an answerQ12) Cholecystectomy patients absorb fat from Cholecystectomy ptwill still absorbing fat from terminal ileum I think well ofcourse fromsmall intestine cholecystectomy has nothing to do with the site ofabsorbtion the person still produces bile( in liver) just no storage or conecentrationof bile thats why post op cholecystectomy patients are put on low fatdiet

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but site of absorbtion remains small intestine (ileum) as usual

Q13)Sputum silver staining for bugs silver staining reminds me of twobugsbut I am not sure Pneumocysyis carinii Legionella pneumoniaeBut silver staining of PCP is done on pts Bronchoalveolar lavage IguessQ14) First thing to say to dad patient brought by 2daughters who express wish to remain with patientBest statement to make to build rapport with patientplaying crossword on encounter May be Doctor have to ask the ptwhether he wants their daughter in the room while interviewingQ15) Post break-up with boyfriend mother of patient finds synthroidtablets in nursing student daughteracirceurotrades belongings Docacirceurotrades responseto patient synthyroid is Thyroid hormone I guess but not sure if it isT3 or T4 the pt may be planning on weight loss because boyfriendhated her obesity q16)Fragile X family parents concern regarding testing of normal 14-year daughteracirceurotrades genome for similar problems Q 17) Girl child dumps classes since uncleacirceurotrades death and mother findsit helpful for daughter to be around home Intervention requiredFamily therapypsychotherapyacirceurobrvbaretc Q18) Porphyrias like the back of ur hands q19) Carbon tetrachloride how it affects liver CCl4 - The liver convertsCCl4 to a CCl3 free radical which damages the liver (fulminanthepatitis fatty change) from Goljans STARS pathology review p93

Acyclovir mechanism of action inhibhits DNA viral poymerase andphosphorylated by viral thymidine kinaseQ20) Hernia above n lateral to pubis Hernia above the inguinal lig isInguinal hernia and below the lig is femoral hernia So it could beboth Indirect and direct inguinal hernia since it doesnt say anythingabout hernias relation to inf epigastric vesselsQ21)Hydatidiform mole learn how to interpret genotypes of moles

Which 2 Joints are Never affected in RA Distal interphalangeal and theBack joints r never involved in RAQ1) Best means of bringing down temperature of seizingpatient with meningitis pharmacologic and otherwise think nonpharamacologic tt shd be hydrotherapy to bring down tempnpharamacologic may be paracetamol by rectal routeQ2) Acetaminophen overdose how it damages In overdose the storesof GSH are depleted and and the metabolite N-acetylbenzoquinoneiminereacts with hepatocytes leading to liver necrosis Acetaminophen formsfree radicals in the liver and results in fulminant hepatitis renalpapillary necrosisdamages by free radicals which r removed by glutathioneNACETYLCYSTEIN its antidote restores the glutathione levelsQ3) Antimicrosomal antibodies involved in hashimotos autoimmunethyroiditis and autoimmune hepatitisQ4)Dialysis patient on transplant list gets angry often and missesdialysis appointments - intervention need to spend more time withpatientdiscuss regardingreconsideration of transplant listacirceurobrvbaretc Dialysis patient on transplantlist gets angry often and misses dialysis appointments - interventionneed to spend more time with patientdiscuss regarding reconsiderationof transplant listacirceurobrvbaretc need to spend more time with patient toknow what exactly is his probQ5) Adenovirus acirceuroldquo structure nonenvelopedds linear DNA icosahedralnucleocapsid only virus with a fibre protruding from each of 12 verticesof teh capsidQ6) Brown fat of neonates Function site of heat production in aneonate---brown adipose tissue contain natural uncoupling proteinwhich allows energy loss in the form of heat to maintain basal tempQ7) Longterm steroid use effect on adrenals adrenal suppressiontherefore tapered slowly neg feed back on ant pit so decreased ACTHso less stim of adrenalsacirceurobrvbarhypothalamo pituitary axis and eventuallyleads to atrophy of the adrenal glandQ8) Trypanosome cruzi life cycle try cruzi lifecycle involves reduvidbud as a vector and both humans and animals as reservoirs life cycleacirceurobrvbar reservoirs are cats dogsacirceurobrvbar reduviid bug passes the trypomastigoteas it bites and scratching implants in bite siteacirceurobrvbaracirceurobrvbaracirceurobrvbarreservoir isrodents armadillos vector is reduviid bug it transmits the trypo-mastigote form which turns into the amastigote form inside the body Atthe bite site the lseion is called chagoma Systemic symptoms are

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fever lymphadenopathy Tachycardia meningoencephalitis Thencomes the intermediate phase where the patient is asymptomatic withlow levels of the parasite and antibodies against it decades later-thechronic form emerges with dilated cardiomyopathy megacolonmegaesophagusTreatment is NifurtimoxQ9)Patient requiring dialysis says donacirceurotradet want machines to keep mealive Docacirceurotrades next step Q10)Antifungals big time Drug interactions Mechanism of actions(letswrite few antifungals with mech of action and main side effectswe willnever forget it if we do so) amphotericin B binds ergosterol creates poresflucytosine-inhibit thymidilate synthaseazole-inhibit ergosterol synthesisgriesofulvin-interfere with microtubule functionterbinafine- inhibit squalene epoxideDRUG INERACTIONSAZOLE GRP INCREASE TOXICITY OF FOLL BY INHIBITING ITSMETABOLISMbdzcisapridecyclosporinefluoxetinelovastatinomeprazoleQ11) Alcoholic with nosebleed Wot to expect in terms of AST PT andforgotacirceurobrvbar( I dont know exactly whats being askedlets see who figuresit out) AST is increased platelet count is decreased prolonged PTQ12)Picture of normal hand and a slender hand shown and asked fordiagnosis Q13)Wernicke mammillary body identification on CT( here just name thestructures affected in wernickes encephalopathy and ofcourse do knowhow to identify themvery very HY) mammillary bodies anddorsomedial nucleus of thalamusacirceurobrvbarMamillary bodies on the ventralsurface of the brain stemQ14) How HBV causes liver cancer HBV DNA integrates in hostgenomic DNAMODIFICATIONOF GENE EXPRESSION HBVINCORPORATES itself into the hepatocyte dna and triggers malignantgrowth theres is a 200 X Risk of developing HCC in carriers versusnoncarriersQ15)Patient taking OCP Smoker Wot u wanna check first smokinginduces met enzymes increased metabolism of OCPSdecreased efficacySmoking itself is thrombogenic and estrogen also isacirceurobrvbar ask for historyof thrombosis may be check PT PTTQ16)Allopurinol acirceuroldquo effect on renal stones It inhibits xanthine oxidasedecreasing uric acidallopurinol used in pts of renal stones as calcium oxalate stone formersare hyperuricemicQ17)Radiation alopecia acirceuroldquo dermal histopathology sparse mixeddermal inflammatory infiltrate consisting mainly of lymphocytes Mucinous deposits confirmed by alcian bluePAS stain were observedwithin the epidermis of the hair follicleQ18)Streptococcus pyogenes acirceuroldquo patient penicillin allergicNext step Can give Clavulanic acid Sulbactam TazobactamCephalosporins should be avoided in patients allergic to penicillinbecause of cross sensitivity Cephalosporins are susceptible to betalactamase but less than penicillin penicillin allergic pts erythromycinor azithromycin are the alternatives all GRP A Streptoccoci r susceptibleto pencillin G but neither Rhematic fever nor allergic pats benefit frompencillin treatment after onset In pencillin allergies pats should geterythromycin or azithromycinHOWEVER ENTEROCOCCAL ENDOCARDITIS CAN BE ERADICATED ONLYBY PENICILLIN OR VANCOMYCIN COMBINED WITH ANAMINOGLYCOSIDEQ19)t-Rna triplet codon function The anti codon on the tRNA pairs withthe codon for aa in mRNA Q20) Nuclear membrane acirceuroldquo evolutionary importance betweeneukaryotes and prokaryotes all I know is nucleus membrane is absentin prokaryotes and present in euk may be evolutionary imp is to protectthe genetic information

there are 4 trigeminal nuclei---gt1)primary sensory nuclei for sensations of face2)spinal trigeminal nucleus for pain and tempreature sensation of face3)Mesencepahalic nucleus for proprioception4)primary motor nucleus for muscles of mastication

ZEBRA genesZ EBV replication activator (ZEBRA) as lytic cycle

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markersZEBRA is one of the immediate early genes of EBVit isconsidered to be expressed in the initial stage of the lytic cycle beforethe viral particles have been dispersed Zebra sign Hemorrhage is often characterized by a typical streakybleeding pattern due to blood spreading in the cerebellar sulci thiszebra-pattern hemorrhage seems to be typical in a postoperative lossof CSF Zebra bodies - lipid inclusions with concentric lamellar structure withalternating light and dark-staining bands in neuronal cells in neimannpicks Zebra tumor = acoustic neuromaQ1)Lead poisoning( symptoms) --Lead poisoningacirceurobrvbar lead inhibitsferrochelatase and ALA dehydraseacirceurobrvbar coproporhyrin and ALAaccumulate in urine sympacirceurordquoabdominal colic sideroblastic anemiawrist and foot drop lead lines in gingivae and epiphysis of long bonesencephalopathy basophilic stipplingQ2) Glutamine in urea cycle Q3) Large intestine gross section tumor shown Type(felt like the napkin constriction)I never heard of this kind oftumoranyone knows Q4) Radiation therapy pelvis Cause for urinary retention cystitsfibrosisQ5) Osteogenesis imperfecta defect d AD mutation in collagen genesQ6) Medial side of arm numbness after mastectomy nerve involvedintercostobrachial n also known as the lateral cutaneous br of theventral primary ramus of T2Q7) Interleukins big time Learn function of eachwe can namesomeand functionIL1- stim produced mainly by macrophages IL2 syn pyrogenic activates TH IL2- downreg TH2 Tcell growthfactor stim BcellIL3- stim BM stem cellsIL4-class switch to IgEIL5-Class swish to eosinophil promote B cell prolifIL6- produc of acute phase reactantsIL8-chemotactic and adhesion of neutrophilsIL10-Inhibit TH1 inhibit cytokine from macrophageIL12-induce TH0 to TH1Q8) Plummer Vinson esophageal defect Esophageal websacirceurobrvbar irondeficiency anemia o Stomatitis o Glossitis o Dysphagia o Spoon-shaped nails o Esophageal webs

Q9)Scurvy enzymereaction involved Prolyl and lysyl hydroxylase theenzymes that catalyzes the hydroxylation require vitamin CQ10)Reiter syndrome vs Sjogren Reiter syndrome--- urethritis conjunctivitis and ant uveitis arthritisSjogrenXerophthalmia xerostomia arthritis parotid enlargementQ11)Managing hypertensive crisis in MAO inhibitor patient on cheeseitacirceurotrades pathogenesis Treatment ot a Hypertensive Crisis from MAOIReactionThis is a medical emergency with cerebral vascular accidents being oneof the greatest concerns Medical consultation is warranted Patientsshould report to an immediately to an emergency department Initialtreatment options include Phentolamine 5 mg IV or Thorazine 50 to 100 mg po Care should be taken to ensure that the patient does not becomedangerously hypotensive or that the hypertensive state returns once theintervention medication has worn off Tyramine is actively transportedinto neurons and displaces NE leading to intraneuronal release of NEIt can be degraded by MAO but if you are on MAOI its interaction willcause tyramine build up Tons of NE will be replaced and hence theHTN crisisQ12) Neurotransmitter involved in Huntington Decreased GABA andAChQ13)Aortic coarctation site of constriction and symptoms infantile typeis preductal Cardiomegaly Pulmonary venous congestion RightVentricular HypertrophyAdult is postductal asso with notching of ribs Displaced esophagealshadow rightward Left Ventricular Hypertrophy HT in UL weak pulsesin LL

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Q14) Chronic antiplatelet drug in aspirin sensitive Clopidogrel ampTiclopidine They are back-up or alternative drugs to aspirin Theyblock ADP receptors on platelets hence decrease activationQ15)Stroke patient getting MI treated with streptokinasedies due to cva Cause concluded that death of the patient occurreddue to rebleeding on administration of streptokinase 1 IntracranialHemorrhage As PRS has mentioned the death could be due to intracranialhemorrhage Since CVA refers to both ischemic (80) andhemorrhagic(20)This is more likely than other explanation to me

2 Therapeutic Failure It could be due to strptokinases property itselfSince most individuals have had a streptococcal infection sometime intheir lives circulating antibodies against streptokinase are likely to bepresent in most patients These antibodies can combine withstreptokinase and neutralize its fibrinolytic properties (Therapeuticfailure)(lippincott Pharmacology 2nd edition p203) 3 Property of all Thrombolytic agents As the thrombolytic agents dissolute clot Increased local thrombinmay occur as the clot dissolves leading to enhanced plateletaggregability and thrombosis Strategies to prevent this includeadministration of antiplatelet drugs such as aspirin orantithrombotics such as heparin

Drugs that have been implicated in the development of serum sickness-like reactions include the following allopurinol (Zyloprim) arsenicalsand mercurial derivatives barbiturates captopril (Capoten)cephalosporins furazolidone (Furoxone) gold salts griseofulvin(Fulvicin Grifulvin) halothane hydralazine (Apresoline) iodidesmethyldopa para-aminosalicylic acid penicillamine penicillinsphenytoin (Dilantin) piperazine procainamide (Procan SR ProcanbidPronestyl-SR) quinidine (Quinaglute Quinalan Quinidex Quinora)streptokinase (Streptase Kabikinase) sulfonamides and thiouracils

Q16)Leukotriene inhibitors ZafirlukastacirceurobrvbarLT receptor antagonistQ17) Chromolyn sodium Mechanism of action prevent degranulation ofmast cellsQ18)Graveacirceurotrades pathophysiology autoimmune TSH receptor antibodiestype II hypersensitivityQ19) Couple in for infertility counseling High BMI Wifesays acirceuroœit kills me not to be able to have a babyacirceuroDocacirceurotrades best response obese wife possibly has Polycystic OvarianSyndrome (PCOS)74 of PCOS pt has infertility and PCOS accounts for 30 of overallinfertilityTherefore the doctor may have to evaluate for PCOS by Lab bloodtest and Ultrasonography The lab blood test will show Increasedandrogen LH fasting insulin prolactin and estrogens Theultrasonography is the most sensitive diagnostic study If the Dx of PCOS have been confirmed Tx should be Weightreduction quit smoking and antiandrogen(because of hirsutism) andantiestrogen(clomiphen)

Q20)Baby awakens at night frightened goes back to sleepDoes not respond to questions b parents on that awakening Best nextstep The boy is possibly having Night Terrors It occurs in Delta sleep so you cant wake them and they cant remember what happened Andnight terror is shown to be precursor to temporal lobe epilepsyThe doctors response should be either examine for any epilepsy in the pt(prevent or tx the temporal lobeepilepsy) or Identify amp dealing with waking-time anxiety to relieve night terrorsceliac disease is the proximal bowel and tropical sprue involves the entire bowel

Q1) Prematue ejaculation Best next step Ans- selective seratononreuptake inhibhitors like fluoxetine or even clorpramine (which is themost seratonin specific hetrocyclics)Q2)Delirium big time ( just define) Ans-Impaired conciousness(incontrast to dementia which is loss of

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

Remembered questions for STEP 1 - USMLE Forum

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

Remembered questions for STEP 1 - USMLE Forum

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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encountered antigen)Vaccine recipients are thus protected against adenovirus acquired byaerosol which could otherwise produce pneumonia

11)x-ray foot with calcification parallel to firstmetatarsal with decreased dorsalis pedis myositis ossificens12)Ligament that holds tibia from goin back ant and posterior cruciateligments--- that holds tibia from going back is Posterior crusiate ligament -----ligament that prevents tibia from coming forward is Anterior cruciateligament13)Obturator nerve section effects obtutaror nerve injury leads to lossof adduction of thigh14)Pelvic ascites site of drainage on standing position the site ofdrainage is vescicouteric pouch in females and rectovescical poch inmales15)Aortic aneurysm rupture effect on urinalysis in thebackground of anuria aortic aneurysm leads to renal infarctionso therewill rbc in urine16)Hand decreased sensation lateral aspect median nerve injury17)Hand sensation ok but extention ofmetacarpophalangeal joints difficult exention and flexion are done bylumbricals and interossis muscles the extension at MP joint by---gtextensors of the fingersflexion at MP joint by---gtlumbricals and introssei so if extension isdifficult means extensors are weakwhich are supplied by radialnerve

18)Clubbing description choices bronchiectasis asthma clubbing isseen in bronchiectasis

Q1) Cystic fibrosis heterozygous frequency Q2) Chemotherapy heart failure acirceuroldquo left heartrightheartmyocardial fibrosis Maybe Doxorubicin (Adriamycin) FA p330 orDaunorubicin But have no idea what is the mechanismQ3) Stimulants and inhibitors of pancreatic secretionsexocrine and endocrine Exocrine- Stimulants CCK Secretin parasympathetics Inhibitors None Endocrine- Insulin Stimulants Glucose Amino Acid GIP Glucagon Insulin Inhibitors Somatostatin Sympathetics (Alpha) Glucagon Stimulants Amino acid Glucagon Inhibitors Insulin Somatostatin

Q4) Cellular barrier between gall bladder cavity andwallacirceurotrades epithelial cells is maybe asking for Tight junction Tightjunction must be there to protect the internal celluar structures fromnasty bileQ5) Embryology neural tube formation cellular dnafragmentation indicates Apoptosis Q6) War veteran describing killing business like acirceuroldquo defence mech

Q7) Trigeminal nerve nucleus identification in medulla ct cross section(you can just say verbally where its located) Q8) Efferent renal constriction effects on GFR ampFiltration fraction GFR amp FF both increasesQ9)Premature birth surfactant and steroid therapy fails due to surfacetension increasedecrease etc Q10) Barret esophageal cancer type Adenocarcinoma since barrettsis Metaplasia full of intesinal cellsQ11)GERD cuz of secretions from which type of gastric cells BRS Physiology(p223) says that the relaxaton of loweresophageal sphincter is vagally mediated and the neurotransmitter isVIP Or maybe GERD could be due to gastric acid therefore parietal cellcould be an answerQ12) Cholecystectomy patients absorb fat from Cholecystectomy ptwill still absorbing fat from terminal ileum I think well ofcourse fromsmall intestine cholecystectomy has nothing to do with the site ofabsorbtion the person still produces bile( in liver) just no storage or conecentrationof bile thats why post op cholecystectomy patients are put on low fatdiet

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but site of absorbtion remains small intestine (ileum) as usual

Q13)Sputum silver staining for bugs silver staining reminds me of twobugsbut I am not sure Pneumocysyis carinii Legionella pneumoniaeBut silver staining of PCP is done on pts Bronchoalveolar lavage IguessQ14) First thing to say to dad patient brought by 2daughters who express wish to remain with patientBest statement to make to build rapport with patientplaying crossword on encounter May be Doctor have to ask the ptwhether he wants their daughter in the room while interviewingQ15) Post break-up with boyfriend mother of patient finds synthroidtablets in nursing student daughteracirceurotrades belongings Docacirceurotrades responseto patient synthyroid is Thyroid hormone I guess but not sure if it isT3 or T4 the pt may be planning on weight loss because boyfriendhated her obesity q16)Fragile X family parents concern regarding testing of normal 14-year daughteracirceurotrades genome for similar problems Q 17) Girl child dumps classes since uncleacirceurotrades death and mother findsit helpful for daughter to be around home Intervention requiredFamily therapypsychotherapyacirceurobrvbaretc Q18) Porphyrias like the back of ur hands q19) Carbon tetrachloride how it affects liver CCl4 - The liver convertsCCl4 to a CCl3 free radical which damages the liver (fulminanthepatitis fatty change) from Goljans STARS pathology review p93

Acyclovir mechanism of action inhibhits DNA viral poymerase andphosphorylated by viral thymidine kinaseQ20) Hernia above n lateral to pubis Hernia above the inguinal lig isInguinal hernia and below the lig is femoral hernia So it could beboth Indirect and direct inguinal hernia since it doesnt say anythingabout hernias relation to inf epigastric vesselsQ21)Hydatidiform mole learn how to interpret genotypes of moles

Which 2 Joints are Never affected in RA Distal interphalangeal and theBack joints r never involved in RAQ1) Best means of bringing down temperature of seizingpatient with meningitis pharmacologic and otherwise think nonpharamacologic tt shd be hydrotherapy to bring down tempnpharamacologic may be paracetamol by rectal routeQ2) Acetaminophen overdose how it damages In overdose the storesof GSH are depleted and and the metabolite N-acetylbenzoquinoneiminereacts with hepatocytes leading to liver necrosis Acetaminophen formsfree radicals in the liver and results in fulminant hepatitis renalpapillary necrosisdamages by free radicals which r removed by glutathioneNACETYLCYSTEIN its antidote restores the glutathione levelsQ3) Antimicrosomal antibodies involved in hashimotos autoimmunethyroiditis and autoimmune hepatitisQ4)Dialysis patient on transplant list gets angry often and missesdialysis appointments - intervention need to spend more time withpatientdiscuss regardingreconsideration of transplant listacirceurobrvbaretc Dialysis patient on transplantlist gets angry often and misses dialysis appointments - interventionneed to spend more time with patientdiscuss regarding reconsiderationof transplant listacirceurobrvbaretc need to spend more time with patient toknow what exactly is his probQ5) Adenovirus acirceuroldquo structure nonenvelopedds linear DNA icosahedralnucleocapsid only virus with a fibre protruding from each of 12 verticesof teh capsidQ6) Brown fat of neonates Function site of heat production in aneonate---brown adipose tissue contain natural uncoupling proteinwhich allows energy loss in the form of heat to maintain basal tempQ7) Longterm steroid use effect on adrenals adrenal suppressiontherefore tapered slowly neg feed back on ant pit so decreased ACTHso less stim of adrenalsacirceurobrvbarhypothalamo pituitary axis and eventuallyleads to atrophy of the adrenal glandQ8) Trypanosome cruzi life cycle try cruzi lifecycle involves reduvidbud as a vector and both humans and animals as reservoirs life cycleacirceurobrvbar reservoirs are cats dogsacirceurobrvbar reduviid bug passes the trypomastigoteas it bites and scratching implants in bite siteacirceurobrvbaracirceurobrvbaracirceurobrvbarreservoir isrodents armadillos vector is reduviid bug it transmits the trypo-mastigote form which turns into the amastigote form inside the body Atthe bite site the lseion is called chagoma Systemic symptoms are

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fever lymphadenopathy Tachycardia meningoencephalitis Thencomes the intermediate phase where the patient is asymptomatic withlow levels of the parasite and antibodies against it decades later-thechronic form emerges with dilated cardiomyopathy megacolonmegaesophagusTreatment is NifurtimoxQ9)Patient requiring dialysis says donacirceurotradet want machines to keep mealive Docacirceurotrades next step Q10)Antifungals big time Drug interactions Mechanism of actions(letswrite few antifungals with mech of action and main side effectswe willnever forget it if we do so) amphotericin B binds ergosterol creates poresflucytosine-inhibit thymidilate synthaseazole-inhibit ergosterol synthesisgriesofulvin-interfere with microtubule functionterbinafine- inhibit squalene epoxideDRUG INERACTIONSAZOLE GRP INCREASE TOXICITY OF FOLL BY INHIBITING ITSMETABOLISMbdzcisapridecyclosporinefluoxetinelovastatinomeprazoleQ11) Alcoholic with nosebleed Wot to expect in terms of AST PT andforgotacirceurobrvbar( I dont know exactly whats being askedlets see who figuresit out) AST is increased platelet count is decreased prolonged PTQ12)Picture of normal hand and a slender hand shown and asked fordiagnosis Q13)Wernicke mammillary body identification on CT( here just name thestructures affected in wernickes encephalopathy and ofcourse do knowhow to identify themvery very HY) mammillary bodies anddorsomedial nucleus of thalamusacirceurobrvbarMamillary bodies on the ventralsurface of the brain stemQ14) How HBV causes liver cancer HBV DNA integrates in hostgenomic DNAMODIFICATIONOF GENE EXPRESSION HBVINCORPORATES itself into the hepatocyte dna and triggers malignantgrowth theres is a 200 X Risk of developing HCC in carriers versusnoncarriersQ15)Patient taking OCP Smoker Wot u wanna check first smokinginduces met enzymes increased metabolism of OCPSdecreased efficacySmoking itself is thrombogenic and estrogen also isacirceurobrvbar ask for historyof thrombosis may be check PT PTTQ16)Allopurinol acirceuroldquo effect on renal stones It inhibits xanthine oxidasedecreasing uric acidallopurinol used in pts of renal stones as calcium oxalate stone formersare hyperuricemicQ17)Radiation alopecia acirceuroldquo dermal histopathology sparse mixeddermal inflammatory infiltrate consisting mainly of lymphocytes Mucinous deposits confirmed by alcian bluePAS stain were observedwithin the epidermis of the hair follicleQ18)Streptococcus pyogenes acirceuroldquo patient penicillin allergicNext step Can give Clavulanic acid Sulbactam TazobactamCephalosporins should be avoided in patients allergic to penicillinbecause of cross sensitivity Cephalosporins are susceptible to betalactamase but less than penicillin penicillin allergic pts erythromycinor azithromycin are the alternatives all GRP A Streptoccoci r susceptibleto pencillin G but neither Rhematic fever nor allergic pats benefit frompencillin treatment after onset In pencillin allergies pats should geterythromycin or azithromycinHOWEVER ENTEROCOCCAL ENDOCARDITIS CAN BE ERADICATED ONLYBY PENICILLIN OR VANCOMYCIN COMBINED WITH ANAMINOGLYCOSIDEQ19)t-Rna triplet codon function The anti codon on the tRNA pairs withthe codon for aa in mRNA Q20) Nuclear membrane acirceuroldquo evolutionary importance betweeneukaryotes and prokaryotes all I know is nucleus membrane is absentin prokaryotes and present in euk may be evolutionary imp is to protectthe genetic information

there are 4 trigeminal nuclei---gt1)primary sensory nuclei for sensations of face2)spinal trigeminal nucleus for pain and tempreature sensation of face3)Mesencepahalic nucleus for proprioception4)primary motor nucleus for muscles of mastication

ZEBRA genesZ EBV replication activator (ZEBRA) as lytic cycle

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markersZEBRA is one of the immediate early genes of EBVit isconsidered to be expressed in the initial stage of the lytic cycle beforethe viral particles have been dispersed Zebra sign Hemorrhage is often characterized by a typical streakybleeding pattern due to blood spreading in the cerebellar sulci thiszebra-pattern hemorrhage seems to be typical in a postoperative lossof CSF Zebra bodies - lipid inclusions with concentric lamellar structure withalternating light and dark-staining bands in neuronal cells in neimannpicks Zebra tumor = acoustic neuromaQ1)Lead poisoning( symptoms) --Lead poisoningacirceurobrvbar lead inhibitsferrochelatase and ALA dehydraseacirceurobrvbar coproporhyrin and ALAaccumulate in urine sympacirceurordquoabdominal colic sideroblastic anemiawrist and foot drop lead lines in gingivae and epiphysis of long bonesencephalopathy basophilic stipplingQ2) Glutamine in urea cycle Q3) Large intestine gross section tumor shown Type(felt like the napkin constriction)I never heard of this kind oftumoranyone knows Q4) Radiation therapy pelvis Cause for urinary retention cystitsfibrosisQ5) Osteogenesis imperfecta defect d AD mutation in collagen genesQ6) Medial side of arm numbness after mastectomy nerve involvedintercostobrachial n also known as the lateral cutaneous br of theventral primary ramus of T2Q7) Interleukins big time Learn function of eachwe can namesomeand functionIL1- stim produced mainly by macrophages IL2 syn pyrogenic activates TH IL2- downreg TH2 Tcell growthfactor stim BcellIL3- stim BM stem cellsIL4-class switch to IgEIL5-Class swish to eosinophil promote B cell prolifIL6- produc of acute phase reactantsIL8-chemotactic and adhesion of neutrophilsIL10-Inhibit TH1 inhibit cytokine from macrophageIL12-induce TH0 to TH1Q8) Plummer Vinson esophageal defect Esophageal websacirceurobrvbar irondeficiency anemia o Stomatitis o Glossitis o Dysphagia o Spoon-shaped nails o Esophageal webs

Q9)Scurvy enzymereaction involved Prolyl and lysyl hydroxylase theenzymes that catalyzes the hydroxylation require vitamin CQ10)Reiter syndrome vs Sjogren Reiter syndrome--- urethritis conjunctivitis and ant uveitis arthritisSjogrenXerophthalmia xerostomia arthritis parotid enlargementQ11)Managing hypertensive crisis in MAO inhibitor patient on cheeseitacirceurotrades pathogenesis Treatment ot a Hypertensive Crisis from MAOIReactionThis is a medical emergency with cerebral vascular accidents being oneof the greatest concerns Medical consultation is warranted Patientsshould report to an immediately to an emergency department Initialtreatment options include Phentolamine 5 mg IV or Thorazine 50 to 100 mg po Care should be taken to ensure that the patient does not becomedangerously hypotensive or that the hypertensive state returns once theintervention medication has worn off Tyramine is actively transportedinto neurons and displaces NE leading to intraneuronal release of NEIt can be degraded by MAO but if you are on MAOI its interaction willcause tyramine build up Tons of NE will be replaced and hence theHTN crisisQ12) Neurotransmitter involved in Huntington Decreased GABA andAChQ13)Aortic coarctation site of constriction and symptoms infantile typeis preductal Cardiomegaly Pulmonary venous congestion RightVentricular HypertrophyAdult is postductal asso with notching of ribs Displaced esophagealshadow rightward Left Ventricular Hypertrophy HT in UL weak pulsesin LL

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Q14) Chronic antiplatelet drug in aspirin sensitive Clopidogrel ampTiclopidine They are back-up or alternative drugs to aspirin Theyblock ADP receptors on platelets hence decrease activationQ15)Stroke patient getting MI treated with streptokinasedies due to cva Cause concluded that death of the patient occurreddue to rebleeding on administration of streptokinase 1 IntracranialHemorrhage As PRS has mentioned the death could be due to intracranialhemorrhage Since CVA refers to both ischemic (80) andhemorrhagic(20)This is more likely than other explanation to me

2 Therapeutic Failure It could be due to strptokinases property itselfSince most individuals have had a streptococcal infection sometime intheir lives circulating antibodies against streptokinase are likely to bepresent in most patients These antibodies can combine withstreptokinase and neutralize its fibrinolytic properties (Therapeuticfailure)(lippincott Pharmacology 2nd edition p203) 3 Property of all Thrombolytic agents As the thrombolytic agents dissolute clot Increased local thrombinmay occur as the clot dissolves leading to enhanced plateletaggregability and thrombosis Strategies to prevent this includeadministration of antiplatelet drugs such as aspirin orantithrombotics such as heparin

Drugs that have been implicated in the development of serum sickness-like reactions include the following allopurinol (Zyloprim) arsenicalsand mercurial derivatives barbiturates captopril (Capoten)cephalosporins furazolidone (Furoxone) gold salts griseofulvin(Fulvicin Grifulvin) halothane hydralazine (Apresoline) iodidesmethyldopa para-aminosalicylic acid penicillamine penicillinsphenytoin (Dilantin) piperazine procainamide (Procan SR ProcanbidPronestyl-SR) quinidine (Quinaglute Quinalan Quinidex Quinora)streptokinase (Streptase Kabikinase) sulfonamides and thiouracils

Q16)Leukotriene inhibitors ZafirlukastacirceurobrvbarLT receptor antagonistQ17) Chromolyn sodium Mechanism of action prevent degranulation ofmast cellsQ18)Graveacirceurotrades pathophysiology autoimmune TSH receptor antibodiestype II hypersensitivityQ19) Couple in for infertility counseling High BMI Wifesays acirceuroœit kills me not to be able to have a babyacirceuroDocacirceurotrades best response obese wife possibly has Polycystic OvarianSyndrome (PCOS)74 of PCOS pt has infertility and PCOS accounts for 30 of overallinfertilityTherefore the doctor may have to evaluate for PCOS by Lab bloodtest and Ultrasonography The lab blood test will show Increasedandrogen LH fasting insulin prolactin and estrogens Theultrasonography is the most sensitive diagnostic study If the Dx of PCOS have been confirmed Tx should be Weightreduction quit smoking and antiandrogen(because of hirsutism) andantiestrogen(clomiphen)

Q20)Baby awakens at night frightened goes back to sleepDoes not respond to questions b parents on that awakening Best nextstep The boy is possibly having Night Terrors It occurs in Delta sleep so you cant wake them and they cant remember what happened Andnight terror is shown to be precursor to temporal lobe epilepsyThe doctors response should be either examine for any epilepsy in the pt(prevent or tx the temporal lobeepilepsy) or Identify amp dealing with waking-time anxiety to relieve night terrorsceliac disease is the proximal bowel and tropical sprue involves the entire bowel

Q1) Prematue ejaculation Best next step Ans- selective seratononreuptake inhibhitors like fluoxetine or even clorpramine (which is themost seratonin specific hetrocyclics)Q2)Delirium big time ( just define) Ans-Impaired conciousness(incontrast to dementia which is loss of

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

Remembered questions for STEP 1 - USMLE Forum

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

Remembered questions for STEP 1 - USMLE Forum

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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but site of absorbtion remains small intestine (ileum) as usual

Q13)Sputum silver staining for bugs silver staining reminds me of twobugsbut I am not sure Pneumocysyis carinii Legionella pneumoniaeBut silver staining of PCP is done on pts Bronchoalveolar lavage IguessQ14) First thing to say to dad patient brought by 2daughters who express wish to remain with patientBest statement to make to build rapport with patientplaying crossword on encounter May be Doctor have to ask the ptwhether he wants their daughter in the room while interviewingQ15) Post break-up with boyfriend mother of patient finds synthroidtablets in nursing student daughteracirceurotrades belongings Docacirceurotrades responseto patient synthyroid is Thyroid hormone I guess but not sure if it isT3 or T4 the pt may be planning on weight loss because boyfriendhated her obesity q16)Fragile X family parents concern regarding testing of normal 14-year daughteracirceurotrades genome for similar problems Q 17) Girl child dumps classes since uncleacirceurotrades death and mother findsit helpful for daughter to be around home Intervention requiredFamily therapypsychotherapyacirceurobrvbaretc Q18) Porphyrias like the back of ur hands q19) Carbon tetrachloride how it affects liver CCl4 - The liver convertsCCl4 to a CCl3 free radical which damages the liver (fulminanthepatitis fatty change) from Goljans STARS pathology review p93

Acyclovir mechanism of action inhibhits DNA viral poymerase andphosphorylated by viral thymidine kinaseQ20) Hernia above n lateral to pubis Hernia above the inguinal lig isInguinal hernia and below the lig is femoral hernia So it could beboth Indirect and direct inguinal hernia since it doesnt say anythingabout hernias relation to inf epigastric vesselsQ21)Hydatidiform mole learn how to interpret genotypes of moles

Which 2 Joints are Never affected in RA Distal interphalangeal and theBack joints r never involved in RAQ1) Best means of bringing down temperature of seizingpatient with meningitis pharmacologic and otherwise think nonpharamacologic tt shd be hydrotherapy to bring down tempnpharamacologic may be paracetamol by rectal routeQ2) Acetaminophen overdose how it damages In overdose the storesof GSH are depleted and and the metabolite N-acetylbenzoquinoneiminereacts with hepatocytes leading to liver necrosis Acetaminophen formsfree radicals in the liver and results in fulminant hepatitis renalpapillary necrosisdamages by free radicals which r removed by glutathioneNACETYLCYSTEIN its antidote restores the glutathione levelsQ3) Antimicrosomal antibodies involved in hashimotos autoimmunethyroiditis and autoimmune hepatitisQ4)Dialysis patient on transplant list gets angry often and missesdialysis appointments - intervention need to spend more time withpatientdiscuss regardingreconsideration of transplant listacirceurobrvbaretc Dialysis patient on transplantlist gets angry often and misses dialysis appointments - interventionneed to spend more time with patientdiscuss regarding reconsiderationof transplant listacirceurobrvbaretc need to spend more time with patient toknow what exactly is his probQ5) Adenovirus acirceuroldquo structure nonenvelopedds linear DNA icosahedralnucleocapsid only virus with a fibre protruding from each of 12 verticesof teh capsidQ6) Brown fat of neonates Function site of heat production in aneonate---brown adipose tissue contain natural uncoupling proteinwhich allows energy loss in the form of heat to maintain basal tempQ7) Longterm steroid use effect on adrenals adrenal suppressiontherefore tapered slowly neg feed back on ant pit so decreased ACTHso less stim of adrenalsacirceurobrvbarhypothalamo pituitary axis and eventuallyleads to atrophy of the adrenal glandQ8) Trypanosome cruzi life cycle try cruzi lifecycle involves reduvidbud as a vector and both humans and animals as reservoirs life cycleacirceurobrvbar reservoirs are cats dogsacirceurobrvbar reduviid bug passes the trypomastigoteas it bites and scratching implants in bite siteacirceurobrvbaracirceurobrvbaracirceurobrvbarreservoir isrodents armadillos vector is reduviid bug it transmits the trypo-mastigote form which turns into the amastigote form inside the body Atthe bite site the lseion is called chagoma Systemic symptoms are

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fever lymphadenopathy Tachycardia meningoencephalitis Thencomes the intermediate phase where the patient is asymptomatic withlow levels of the parasite and antibodies against it decades later-thechronic form emerges with dilated cardiomyopathy megacolonmegaesophagusTreatment is NifurtimoxQ9)Patient requiring dialysis says donacirceurotradet want machines to keep mealive Docacirceurotrades next step Q10)Antifungals big time Drug interactions Mechanism of actions(letswrite few antifungals with mech of action and main side effectswe willnever forget it if we do so) amphotericin B binds ergosterol creates poresflucytosine-inhibit thymidilate synthaseazole-inhibit ergosterol synthesisgriesofulvin-interfere with microtubule functionterbinafine- inhibit squalene epoxideDRUG INERACTIONSAZOLE GRP INCREASE TOXICITY OF FOLL BY INHIBITING ITSMETABOLISMbdzcisapridecyclosporinefluoxetinelovastatinomeprazoleQ11) Alcoholic with nosebleed Wot to expect in terms of AST PT andforgotacirceurobrvbar( I dont know exactly whats being askedlets see who figuresit out) AST is increased platelet count is decreased prolonged PTQ12)Picture of normal hand and a slender hand shown and asked fordiagnosis Q13)Wernicke mammillary body identification on CT( here just name thestructures affected in wernickes encephalopathy and ofcourse do knowhow to identify themvery very HY) mammillary bodies anddorsomedial nucleus of thalamusacirceurobrvbarMamillary bodies on the ventralsurface of the brain stemQ14) How HBV causes liver cancer HBV DNA integrates in hostgenomic DNAMODIFICATIONOF GENE EXPRESSION HBVINCORPORATES itself into the hepatocyte dna and triggers malignantgrowth theres is a 200 X Risk of developing HCC in carriers versusnoncarriersQ15)Patient taking OCP Smoker Wot u wanna check first smokinginduces met enzymes increased metabolism of OCPSdecreased efficacySmoking itself is thrombogenic and estrogen also isacirceurobrvbar ask for historyof thrombosis may be check PT PTTQ16)Allopurinol acirceuroldquo effect on renal stones It inhibits xanthine oxidasedecreasing uric acidallopurinol used in pts of renal stones as calcium oxalate stone formersare hyperuricemicQ17)Radiation alopecia acirceuroldquo dermal histopathology sparse mixeddermal inflammatory infiltrate consisting mainly of lymphocytes Mucinous deposits confirmed by alcian bluePAS stain were observedwithin the epidermis of the hair follicleQ18)Streptococcus pyogenes acirceuroldquo patient penicillin allergicNext step Can give Clavulanic acid Sulbactam TazobactamCephalosporins should be avoided in patients allergic to penicillinbecause of cross sensitivity Cephalosporins are susceptible to betalactamase but less than penicillin penicillin allergic pts erythromycinor azithromycin are the alternatives all GRP A Streptoccoci r susceptibleto pencillin G but neither Rhematic fever nor allergic pats benefit frompencillin treatment after onset In pencillin allergies pats should geterythromycin or azithromycinHOWEVER ENTEROCOCCAL ENDOCARDITIS CAN BE ERADICATED ONLYBY PENICILLIN OR VANCOMYCIN COMBINED WITH ANAMINOGLYCOSIDEQ19)t-Rna triplet codon function The anti codon on the tRNA pairs withthe codon for aa in mRNA Q20) Nuclear membrane acirceuroldquo evolutionary importance betweeneukaryotes and prokaryotes all I know is nucleus membrane is absentin prokaryotes and present in euk may be evolutionary imp is to protectthe genetic information

there are 4 trigeminal nuclei---gt1)primary sensory nuclei for sensations of face2)spinal trigeminal nucleus for pain and tempreature sensation of face3)Mesencepahalic nucleus for proprioception4)primary motor nucleus for muscles of mastication

ZEBRA genesZ EBV replication activator (ZEBRA) as lytic cycle

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markersZEBRA is one of the immediate early genes of EBVit isconsidered to be expressed in the initial stage of the lytic cycle beforethe viral particles have been dispersed Zebra sign Hemorrhage is often characterized by a typical streakybleeding pattern due to blood spreading in the cerebellar sulci thiszebra-pattern hemorrhage seems to be typical in a postoperative lossof CSF Zebra bodies - lipid inclusions with concentric lamellar structure withalternating light and dark-staining bands in neuronal cells in neimannpicks Zebra tumor = acoustic neuromaQ1)Lead poisoning( symptoms) --Lead poisoningacirceurobrvbar lead inhibitsferrochelatase and ALA dehydraseacirceurobrvbar coproporhyrin and ALAaccumulate in urine sympacirceurordquoabdominal colic sideroblastic anemiawrist and foot drop lead lines in gingivae and epiphysis of long bonesencephalopathy basophilic stipplingQ2) Glutamine in urea cycle Q3) Large intestine gross section tumor shown Type(felt like the napkin constriction)I never heard of this kind oftumoranyone knows Q4) Radiation therapy pelvis Cause for urinary retention cystitsfibrosisQ5) Osteogenesis imperfecta defect d AD mutation in collagen genesQ6) Medial side of arm numbness after mastectomy nerve involvedintercostobrachial n also known as the lateral cutaneous br of theventral primary ramus of T2Q7) Interleukins big time Learn function of eachwe can namesomeand functionIL1- stim produced mainly by macrophages IL2 syn pyrogenic activates TH IL2- downreg TH2 Tcell growthfactor stim BcellIL3- stim BM stem cellsIL4-class switch to IgEIL5-Class swish to eosinophil promote B cell prolifIL6- produc of acute phase reactantsIL8-chemotactic and adhesion of neutrophilsIL10-Inhibit TH1 inhibit cytokine from macrophageIL12-induce TH0 to TH1Q8) Plummer Vinson esophageal defect Esophageal websacirceurobrvbar irondeficiency anemia o Stomatitis o Glossitis o Dysphagia o Spoon-shaped nails o Esophageal webs

Q9)Scurvy enzymereaction involved Prolyl and lysyl hydroxylase theenzymes that catalyzes the hydroxylation require vitamin CQ10)Reiter syndrome vs Sjogren Reiter syndrome--- urethritis conjunctivitis and ant uveitis arthritisSjogrenXerophthalmia xerostomia arthritis parotid enlargementQ11)Managing hypertensive crisis in MAO inhibitor patient on cheeseitacirceurotrades pathogenesis Treatment ot a Hypertensive Crisis from MAOIReactionThis is a medical emergency with cerebral vascular accidents being oneof the greatest concerns Medical consultation is warranted Patientsshould report to an immediately to an emergency department Initialtreatment options include Phentolamine 5 mg IV or Thorazine 50 to 100 mg po Care should be taken to ensure that the patient does not becomedangerously hypotensive or that the hypertensive state returns once theintervention medication has worn off Tyramine is actively transportedinto neurons and displaces NE leading to intraneuronal release of NEIt can be degraded by MAO but if you are on MAOI its interaction willcause tyramine build up Tons of NE will be replaced and hence theHTN crisisQ12) Neurotransmitter involved in Huntington Decreased GABA andAChQ13)Aortic coarctation site of constriction and symptoms infantile typeis preductal Cardiomegaly Pulmonary venous congestion RightVentricular HypertrophyAdult is postductal asso with notching of ribs Displaced esophagealshadow rightward Left Ventricular Hypertrophy HT in UL weak pulsesin LL

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Q14) Chronic antiplatelet drug in aspirin sensitive Clopidogrel ampTiclopidine They are back-up or alternative drugs to aspirin Theyblock ADP receptors on platelets hence decrease activationQ15)Stroke patient getting MI treated with streptokinasedies due to cva Cause concluded that death of the patient occurreddue to rebleeding on administration of streptokinase 1 IntracranialHemorrhage As PRS has mentioned the death could be due to intracranialhemorrhage Since CVA refers to both ischemic (80) andhemorrhagic(20)This is more likely than other explanation to me

2 Therapeutic Failure It could be due to strptokinases property itselfSince most individuals have had a streptococcal infection sometime intheir lives circulating antibodies against streptokinase are likely to bepresent in most patients These antibodies can combine withstreptokinase and neutralize its fibrinolytic properties (Therapeuticfailure)(lippincott Pharmacology 2nd edition p203) 3 Property of all Thrombolytic agents As the thrombolytic agents dissolute clot Increased local thrombinmay occur as the clot dissolves leading to enhanced plateletaggregability and thrombosis Strategies to prevent this includeadministration of antiplatelet drugs such as aspirin orantithrombotics such as heparin

Drugs that have been implicated in the development of serum sickness-like reactions include the following allopurinol (Zyloprim) arsenicalsand mercurial derivatives barbiturates captopril (Capoten)cephalosporins furazolidone (Furoxone) gold salts griseofulvin(Fulvicin Grifulvin) halothane hydralazine (Apresoline) iodidesmethyldopa para-aminosalicylic acid penicillamine penicillinsphenytoin (Dilantin) piperazine procainamide (Procan SR ProcanbidPronestyl-SR) quinidine (Quinaglute Quinalan Quinidex Quinora)streptokinase (Streptase Kabikinase) sulfonamides and thiouracils

Q16)Leukotriene inhibitors ZafirlukastacirceurobrvbarLT receptor antagonistQ17) Chromolyn sodium Mechanism of action prevent degranulation ofmast cellsQ18)Graveacirceurotrades pathophysiology autoimmune TSH receptor antibodiestype II hypersensitivityQ19) Couple in for infertility counseling High BMI Wifesays acirceuroœit kills me not to be able to have a babyacirceuroDocacirceurotrades best response obese wife possibly has Polycystic OvarianSyndrome (PCOS)74 of PCOS pt has infertility and PCOS accounts for 30 of overallinfertilityTherefore the doctor may have to evaluate for PCOS by Lab bloodtest and Ultrasonography The lab blood test will show Increasedandrogen LH fasting insulin prolactin and estrogens Theultrasonography is the most sensitive diagnostic study If the Dx of PCOS have been confirmed Tx should be Weightreduction quit smoking and antiandrogen(because of hirsutism) andantiestrogen(clomiphen)

Q20)Baby awakens at night frightened goes back to sleepDoes not respond to questions b parents on that awakening Best nextstep The boy is possibly having Night Terrors It occurs in Delta sleep so you cant wake them and they cant remember what happened Andnight terror is shown to be precursor to temporal lobe epilepsyThe doctors response should be either examine for any epilepsy in the pt(prevent or tx the temporal lobeepilepsy) or Identify amp dealing with waking-time anxiety to relieve night terrorsceliac disease is the proximal bowel and tropical sprue involves the entire bowel

Q1) Prematue ejaculation Best next step Ans- selective seratononreuptake inhibhitors like fluoxetine or even clorpramine (which is themost seratonin specific hetrocyclics)Q2)Delirium big time ( just define) Ans-Impaired conciousness(incontrast to dementia which is loss of

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

Remembered questions for STEP 1 - USMLE Forum

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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fever lymphadenopathy Tachycardia meningoencephalitis Thencomes the intermediate phase where the patient is asymptomatic withlow levels of the parasite and antibodies against it decades later-thechronic form emerges with dilated cardiomyopathy megacolonmegaesophagusTreatment is NifurtimoxQ9)Patient requiring dialysis says donacirceurotradet want machines to keep mealive Docacirceurotrades next step Q10)Antifungals big time Drug interactions Mechanism of actions(letswrite few antifungals with mech of action and main side effectswe willnever forget it if we do so) amphotericin B binds ergosterol creates poresflucytosine-inhibit thymidilate synthaseazole-inhibit ergosterol synthesisgriesofulvin-interfere with microtubule functionterbinafine- inhibit squalene epoxideDRUG INERACTIONSAZOLE GRP INCREASE TOXICITY OF FOLL BY INHIBITING ITSMETABOLISMbdzcisapridecyclosporinefluoxetinelovastatinomeprazoleQ11) Alcoholic with nosebleed Wot to expect in terms of AST PT andforgotacirceurobrvbar( I dont know exactly whats being askedlets see who figuresit out) AST is increased platelet count is decreased prolonged PTQ12)Picture of normal hand and a slender hand shown and asked fordiagnosis Q13)Wernicke mammillary body identification on CT( here just name thestructures affected in wernickes encephalopathy and ofcourse do knowhow to identify themvery very HY) mammillary bodies anddorsomedial nucleus of thalamusacirceurobrvbarMamillary bodies on the ventralsurface of the brain stemQ14) How HBV causes liver cancer HBV DNA integrates in hostgenomic DNAMODIFICATIONOF GENE EXPRESSION HBVINCORPORATES itself into the hepatocyte dna and triggers malignantgrowth theres is a 200 X Risk of developing HCC in carriers versusnoncarriersQ15)Patient taking OCP Smoker Wot u wanna check first smokinginduces met enzymes increased metabolism of OCPSdecreased efficacySmoking itself is thrombogenic and estrogen also isacirceurobrvbar ask for historyof thrombosis may be check PT PTTQ16)Allopurinol acirceuroldquo effect on renal stones It inhibits xanthine oxidasedecreasing uric acidallopurinol used in pts of renal stones as calcium oxalate stone formersare hyperuricemicQ17)Radiation alopecia acirceuroldquo dermal histopathology sparse mixeddermal inflammatory infiltrate consisting mainly of lymphocytes Mucinous deposits confirmed by alcian bluePAS stain were observedwithin the epidermis of the hair follicleQ18)Streptococcus pyogenes acirceuroldquo patient penicillin allergicNext step Can give Clavulanic acid Sulbactam TazobactamCephalosporins should be avoided in patients allergic to penicillinbecause of cross sensitivity Cephalosporins are susceptible to betalactamase but less than penicillin penicillin allergic pts erythromycinor azithromycin are the alternatives all GRP A Streptoccoci r susceptibleto pencillin G but neither Rhematic fever nor allergic pats benefit frompencillin treatment after onset In pencillin allergies pats should geterythromycin or azithromycinHOWEVER ENTEROCOCCAL ENDOCARDITIS CAN BE ERADICATED ONLYBY PENICILLIN OR VANCOMYCIN COMBINED WITH ANAMINOGLYCOSIDEQ19)t-Rna triplet codon function The anti codon on the tRNA pairs withthe codon for aa in mRNA Q20) Nuclear membrane acirceuroldquo evolutionary importance betweeneukaryotes and prokaryotes all I know is nucleus membrane is absentin prokaryotes and present in euk may be evolutionary imp is to protectthe genetic information

there are 4 trigeminal nuclei---gt1)primary sensory nuclei for sensations of face2)spinal trigeminal nucleus for pain and tempreature sensation of face3)Mesencepahalic nucleus for proprioception4)primary motor nucleus for muscles of mastication

ZEBRA genesZ EBV replication activator (ZEBRA) as lytic cycle

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markersZEBRA is one of the immediate early genes of EBVit isconsidered to be expressed in the initial stage of the lytic cycle beforethe viral particles have been dispersed Zebra sign Hemorrhage is often characterized by a typical streakybleeding pattern due to blood spreading in the cerebellar sulci thiszebra-pattern hemorrhage seems to be typical in a postoperative lossof CSF Zebra bodies - lipid inclusions with concentric lamellar structure withalternating light and dark-staining bands in neuronal cells in neimannpicks Zebra tumor = acoustic neuromaQ1)Lead poisoning( symptoms) --Lead poisoningacirceurobrvbar lead inhibitsferrochelatase and ALA dehydraseacirceurobrvbar coproporhyrin and ALAaccumulate in urine sympacirceurordquoabdominal colic sideroblastic anemiawrist and foot drop lead lines in gingivae and epiphysis of long bonesencephalopathy basophilic stipplingQ2) Glutamine in urea cycle Q3) Large intestine gross section tumor shown Type(felt like the napkin constriction)I never heard of this kind oftumoranyone knows Q4) Radiation therapy pelvis Cause for urinary retention cystitsfibrosisQ5) Osteogenesis imperfecta defect d AD mutation in collagen genesQ6) Medial side of arm numbness after mastectomy nerve involvedintercostobrachial n also known as the lateral cutaneous br of theventral primary ramus of T2Q7) Interleukins big time Learn function of eachwe can namesomeand functionIL1- stim produced mainly by macrophages IL2 syn pyrogenic activates TH IL2- downreg TH2 Tcell growthfactor stim BcellIL3- stim BM stem cellsIL4-class switch to IgEIL5-Class swish to eosinophil promote B cell prolifIL6- produc of acute phase reactantsIL8-chemotactic and adhesion of neutrophilsIL10-Inhibit TH1 inhibit cytokine from macrophageIL12-induce TH0 to TH1Q8) Plummer Vinson esophageal defect Esophageal websacirceurobrvbar irondeficiency anemia o Stomatitis o Glossitis o Dysphagia o Spoon-shaped nails o Esophageal webs

Q9)Scurvy enzymereaction involved Prolyl and lysyl hydroxylase theenzymes that catalyzes the hydroxylation require vitamin CQ10)Reiter syndrome vs Sjogren Reiter syndrome--- urethritis conjunctivitis and ant uveitis arthritisSjogrenXerophthalmia xerostomia arthritis parotid enlargementQ11)Managing hypertensive crisis in MAO inhibitor patient on cheeseitacirceurotrades pathogenesis Treatment ot a Hypertensive Crisis from MAOIReactionThis is a medical emergency with cerebral vascular accidents being oneof the greatest concerns Medical consultation is warranted Patientsshould report to an immediately to an emergency department Initialtreatment options include Phentolamine 5 mg IV or Thorazine 50 to 100 mg po Care should be taken to ensure that the patient does not becomedangerously hypotensive or that the hypertensive state returns once theintervention medication has worn off Tyramine is actively transportedinto neurons and displaces NE leading to intraneuronal release of NEIt can be degraded by MAO but if you are on MAOI its interaction willcause tyramine build up Tons of NE will be replaced and hence theHTN crisisQ12) Neurotransmitter involved in Huntington Decreased GABA andAChQ13)Aortic coarctation site of constriction and symptoms infantile typeis preductal Cardiomegaly Pulmonary venous congestion RightVentricular HypertrophyAdult is postductal asso with notching of ribs Displaced esophagealshadow rightward Left Ventricular Hypertrophy HT in UL weak pulsesin LL

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Q14) Chronic antiplatelet drug in aspirin sensitive Clopidogrel ampTiclopidine They are back-up or alternative drugs to aspirin Theyblock ADP receptors on platelets hence decrease activationQ15)Stroke patient getting MI treated with streptokinasedies due to cva Cause concluded that death of the patient occurreddue to rebleeding on administration of streptokinase 1 IntracranialHemorrhage As PRS has mentioned the death could be due to intracranialhemorrhage Since CVA refers to both ischemic (80) andhemorrhagic(20)This is more likely than other explanation to me

2 Therapeutic Failure It could be due to strptokinases property itselfSince most individuals have had a streptococcal infection sometime intheir lives circulating antibodies against streptokinase are likely to bepresent in most patients These antibodies can combine withstreptokinase and neutralize its fibrinolytic properties (Therapeuticfailure)(lippincott Pharmacology 2nd edition p203) 3 Property of all Thrombolytic agents As the thrombolytic agents dissolute clot Increased local thrombinmay occur as the clot dissolves leading to enhanced plateletaggregability and thrombosis Strategies to prevent this includeadministration of antiplatelet drugs such as aspirin orantithrombotics such as heparin

Drugs that have been implicated in the development of serum sickness-like reactions include the following allopurinol (Zyloprim) arsenicalsand mercurial derivatives barbiturates captopril (Capoten)cephalosporins furazolidone (Furoxone) gold salts griseofulvin(Fulvicin Grifulvin) halothane hydralazine (Apresoline) iodidesmethyldopa para-aminosalicylic acid penicillamine penicillinsphenytoin (Dilantin) piperazine procainamide (Procan SR ProcanbidPronestyl-SR) quinidine (Quinaglute Quinalan Quinidex Quinora)streptokinase (Streptase Kabikinase) sulfonamides and thiouracils

Q16)Leukotriene inhibitors ZafirlukastacirceurobrvbarLT receptor antagonistQ17) Chromolyn sodium Mechanism of action prevent degranulation ofmast cellsQ18)Graveacirceurotrades pathophysiology autoimmune TSH receptor antibodiestype II hypersensitivityQ19) Couple in for infertility counseling High BMI Wifesays acirceuroœit kills me not to be able to have a babyacirceuroDocacirceurotrades best response obese wife possibly has Polycystic OvarianSyndrome (PCOS)74 of PCOS pt has infertility and PCOS accounts for 30 of overallinfertilityTherefore the doctor may have to evaluate for PCOS by Lab bloodtest and Ultrasonography The lab blood test will show Increasedandrogen LH fasting insulin prolactin and estrogens Theultrasonography is the most sensitive diagnostic study If the Dx of PCOS have been confirmed Tx should be Weightreduction quit smoking and antiandrogen(because of hirsutism) andantiestrogen(clomiphen)

Q20)Baby awakens at night frightened goes back to sleepDoes not respond to questions b parents on that awakening Best nextstep The boy is possibly having Night Terrors It occurs in Delta sleep so you cant wake them and they cant remember what happened Andnight terror is shown to be precursor to temporal lobe epilepsyThe doctors response should be either examine for any epilepsy in the pt(prevent or tx the temporal lobeepilepsy) or Identify amp dealing with waking-time anxiety to relieve night terrorsceliac disease is the proximal bowel and tropical sprue involves the entire bowel

Q1) Prematue ejaculation Best next step Ans- selective seratononreuptake inhibhitors like fluoxetine or even clorpramine (which is themost seratonin specific hetrocyclics)Q2)Delirium big time ( just define) Ans-Impaired conciousness(incontrast to dementia which is loss of

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

Remembered questions for STEP 1 - USMLE Forum

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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markersZEBRA is one of the immediate early genes of EBVit isconsidered to be expressed in the initial stage of the lytic cycle beforethe viral particles have been dispersed Zebra sign Hemorrhage is often characterized by a typical streakybleeding pattern due to blood spreading in the cerebellar sulci thiszebra-pattern hemorrhage seems to be typical in a postoperative lossof CSF Zebra bodies - lipid inclusions with concentric lamellar structure withalternating light and dark-staining bands in neuronal cells in neimannpicks Zebra tumor = acoustic neuromaQ1)Lead poisoning( symptoms) --Lead poisoningacirceurobrvbar lead inhibitsferrochelatase and ALA dehydraseacirceurobrvbar coproporhyrin and ALAaccumulate in urine sympacirceurordquoabdominal colic sideroblastic anemiawrist and foot drop lead lines in gingivae and epiphysis of long bonesencephalopathy basophilic stipplingQ2) Glutamine in urea cycle Q3) Large intestine gross section tumor shown Type(felt like the napkin constriction)I never heard of this kind oftumoranyone knows Q4) Radiation therapy pelvis Cause for urinary retention cystitsfibrosisQ5) Osteogenesis imperfecta defect d AD mutation in collagen genesQ6) Medial side of arm numbness after mastectomy nerve involvedintercostobrachial n also known as the lateral cutaneous br of theventral primary ramus of T2Q7) Interleukins big time Learn function of eachwe can namesomeand functionIL1- stim produced mainly by macrophages IL2 syn pyrogenic activates TH IL2- downreg TH2 Tcell growthfactor stim BcellIL3- stim BM stem cellsIL4-class switch to IgEIL5-Class swish to eosinophil promote B cell prolifIL6- produc of acute phase reactantsIL8-chemotactic and adhesion of neutrophilsIL10-Inhibit TH1 inhibit cytokine from macrophageIL12-induce TH0 to TH1Q8) Plummer Vinson esophageal defect Esophageal websacirceurobrvbar irondeficiency anemia o Stomatitis o Glossitis o Dysphagia o Spoon-shaped nails o Esophageal webs

Q9)Scurvy enzymereaction involved Prolyl and lysyl hydroxylase theenzymes that catalyzes the hydroxylation require vitamin CQ10)Reiter syndrome vs Sjogren Reiter syndrome--- urethritis conjunctivitis and ant uveitis arthritisSjogrenXerophthalmia xerostomia arthritis parotid enlargementQ11)Managing hypertensive crisis in MAO inhibitor patient on cheeseitacirceurotrades pathogenesis Treatment ot a Hypertensive Crisis from MAOIReactionThis is a medical emergency with cerebral vascular accidents being oneof the greatest concerns Medical consultation is warranted Patientsshould report to an immediately to an emergency department Initialtreatment options include Phentolamine 5 mg IV or Thorazine 50 to 100 mg po Care should be taken to ensure that the patient does not becomedangerously hypotensive or that the hypertensive state returns once theintervention medication has worn off Tyramine is actively transportedinto neurons and displaces NE leading to intraneuronal release of NEIt can be degraded by MAO but if you are on MAOI its interaction willcause tyramine build up Tons of NE will be replaced and hence theHTN crisisQ12) Neurotransmitter involved in Huntington Decreased GABA andAChQ13)Aortic coarctation site of constriction and symptoms infantile typeis preductal Cardiomegaly Pulmonary venous congestion RightVentricular HypertrophyAdult is postductal asso with notching of ribs Displaced esophagealshadow rightward Left Ventricular Hypertrophy HT in UL weak pulsesin LL

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Q14) Chronic antiplatelet drug in aspirin sensitive Clopidogrel ampTiclopidine They are back-up or alternative drugs to aspirin Theyblock ADP receptors on platelets hence decrease activationQ15)Stroke patient getting MI treated with streptokinasedies due to cva Cause concluded that death of the patient occurreddue to rebleeding on administration of streptokinase 1 IntracranialHemorrhage As PRS has mentioned the death could be due to intracranialhemorrhage Since CVA refers to both ischemic (80) andhemorrhagic(20)This is more likely than other explanation to me

2 Therapeutic Failure It could be due to strptokinases property itselfSince most individuals have had a streptococcal infection sometime intheir lives circulating antibodies against streptokinase are likely to bepresent in most patients These antibodies can combine withstreptokinase and neutralize its fibrinolytic properties (Therapeuticfailure)(lippincott Pharmacology 2nd edition p203) 3 Property of all Thrombolytic agents As the thrombolytic agents dissolute clot Increased local thrombinmay occur as the clot dissolves leading to enhanced plateletaggregability and thrombosis Strategies to prevent this includeadministration of antiplatelet drugs such as aspirin orantithrombotics such as heparin

Drugs that have been implicated in the development of serum sickness-like reactions include the following allopurinol (Zyloprim) arsenicalsand mercurial derivatives barbiturates captopril (Capoten)cephalosporins furazolidone (Furoxone) gold salts griseofulvin(Fulvicin Grifulvin) halothane hydralazine (Apresoline) iodidesmethyldopa para-aminosalicylic acid penicillamine penicillinsphenytoin (Dilantin) piperazine procainamide (Procan SR ProcanbidPronestyl-SR) quinidine (Quinaglute Quinalan Quinidex Quinora)streptokinase (Streptase Kabikinase) sulfonamides and thiouracils

Q16)Leukotriene inhibitors ZafirlukastacirceurobrvbarLT receptor antagonistQ17) Chromolyn sodium Mechanism of action prevent degranulation ofmast cellsQ18)Graveacirceurotrades pathophysiology autoimmune TSH receptor antibodiestype II hypersensitivityQ19) Couple in for infertility counseling High BMI Wifesays acirceuroœit kills me not to be able to have a babyacirceuroDocacirceurotrades best response obese wife possibly has Polycystic OvarianSyndrome (PCOS)74 of PCOS pt has infertility and PCOS accounts for 30 of overallinfertilityTherefore the doctor may have to evaluate for PCOS by Lab bloodtest and Ultrasonography The lab blood test will show Increasedandrogen LH fasting insulin prolactin and estrogens Theultrasonography is the most sensitive diagnostic study If the Dx of PCOS have been confirmed Tx should be Weightreduction quit smoking and antiandrogen(because of hirsutism) andantiestrogen(clomiphen)

Q20)Baby awakens at night frightened goes back to sleepDoes not respond to questions b parents on that awakening Best nextstep The boy is possibly having Night Terrors It occurs in Delta sleep so you cant wake them and they cant remember what happened Andnight terror is shown to be precursor to temporal lobe epilepsyThe doctors response should be either examine for any epilepsy in the pt(prevent or tx the temporal lobeepilepsy) or Identify amp dealing with waking-time anxiety to relieve night terrorsceliac disease is the proximal bowel and tropical sprue involves the entire bowel

Q1) Prematue ejaculation Best next step Ans- selective seratononreuptake inhibhitors like fluoxetine or even clorpramine (which is themost seratonin specific hetrocyclics)Q2)Delirium big time ( just define) Ans-Impaired conciousness(incontrast to dementia which is loss of

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

Remembered questions for STEP 1 - USMLE Forum

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Q14) Chronic antiplatelet drug in aspirin sensitive Clopidogrel ampTiclopidine They are back-up or alternative drugs to aspirin Theyblock ADP receptors on platelets hence decrease activationQ15)Stroke patient getting MI treated with streptokinasedies due to cva Cause concluded that death of the patient occurreddue to rebleeding on administration of streptokinase 1 IntracranialHemorrhage As PRS has mentioned the death could be due to intracranialhemorrhage Since CVA refers to both ischemic (80) andhemorrhagic(20)This is more likely than other explanation to me

2 Therapeutic Failure It could be due to strptokinases property itselfSince most individuals have had a streptococcal infection sometime intheir lives circulating antibodies against streptokinase are likely to bepresent in most patients These antibodies can combine withstreptokinase and neutralize its fibrinolytic properties (Therapeuticfailure)(lippincott Pharmacology 2nd edition p203) 3 Property of all Thrombolytic agents As the thrombolytic agents dissolute clot Increased local thrombinmay occur as the clot dissolves leading to enhanced plateletaggregability and thrombosis Strategies to prevent this includeadministration of antiplatelet drugs such as aspirin orantithrombotics such as heparin

Drugs that have been implicated in the development of serum sickness-like reactions include the following allopurinol (Zyloprim) arsenicalsand mercurial derivatives barbiturates captopril (Capoten)cephalosporins furazolidone (Furoxone) gold salts griseofulvin(Fulvicin Grifulvin) halothane hydralazine (Apresoline) iodidesmethyldopa para-aminosalicylic acid penicillamine penicillinsphenytoin (Dilantin) piperazine procainamide (Procan SR ProcanbidPronestyl-SR) quinidine (Quinaglute Quinalan Quinidex Quinora)streptokinase (Streptase Kabikinase) sulfonamides and thiouracils

Q16)Leukotriene inhibitors ZafirlukastacirceurobrvbarLT receptor antagonistQ17) Chromolyn sodium Mechanism of action prevent degranulation ofmast cellsQ18)Graveacirceurotrades pathophysiology autoimmune TSH receptor antibodiestype II hypersensitivityQ19) Couple in for infertility counseling High BMI Wifesays acirceuroœit kills me not to be able to have a babyacirceuroDocacirceurotrades best response obese wife possibly has Polycystic OvarianSyndrome (PCOS)74 of PCOS pt has infertility and PCOS accounts for 30 of overallinfertilityTherefore the doctor may have to evaluate for PCOS by Lab bloodtest and Ultrasonography The lab blood test will show Increasedandrogen LH fasting insulin prolactin and estrogens Theultrasonography is the most sensitive diagnostic study If the Dx of PCOS have been confirmed Tx should be Weightreduction quit smoking and antiandrogen(because of hirsutism) andantiestrogen(clomiphen)

Q20)Baby awakens at night frightened goes back to sleepDoes not respond to questions b parents on that awakening Best nextstep The boy is possibly having Night Terrors It occurs in Delta sleep so you cant wake them and they cant remember what happened Andnight terror is shown to be precursor to temporal lobe epilepsyThe doctors response should be either examine for any epilepsy in the pt(prevent or tx the temporal lobeepilepsy) or Identify amp dealing with waking-time anxiety to relieve night terrorsceliac disease is the proximal bowel and tropical sprue involves the entire bowel

Q1) Prematue ejaculation Best next step Ans- selective seratononreuptake inhibhitors like fluoxetine or even clorpramine (which is themost seratonin specific hetrocyclics)Q2)Delirium big time ( just define) Ans-Impaired conciousness(incontrast to dementia which is loss of

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

Remembered questions for STEP 1 - USMLE Forum

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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memory and intellectual abilities)causes-Huntingtons or parkinsons ds CNS infectiontrauma systemicds( like hepatic cardiovascular) high fever substance abuse orwithdrawalmore common occurrence in children and elderlyassociated physical findings-autonomic dysfunction acute medical illnessamd ABNORMAL EEGassociated psycho findings-illusions hallucinations impairedconciousness sundowning(symptoms worse at night)treatment- removal of underlying cause will allow symptoms to resolveQ3)Malingering vs factitious Ans-factitious-when individual tries tosimulate an illness for attention from medical personnel and can evenundergo unnecessary medical and surgical proceduresMalingering-when the same is done for financial or other obvious gainQ4)Leuprolide mechanism of action ans- its a GnRH agonist and causescontinued secretion of Gn from ant pituitary which causes thedownregulation of Gn receptors---gtinhibhition of FSH and LH---gtsupressed gonadal functionused in treating precosious pubery prostatic Caendometriosispremenopausal breast Cautrine leomyoma PCODcan also be usedas contraceptive in both males and femalesQ5) Thromboangitis obliterans( discuss in afew lines) Ans-also calledbuergers dsaffects most commonly smokersit affects the wholeneurovascular bundle of tibial poplteal or radial arteriesthe thrombus is composed of neutrophil containing micro abscessesPtsfrequently have raynauds phenomenonQ6)Lack of T tubules in muscles lead toacirceurobrvbar I think lack of T tubules inmuscle will affect the membrane depolarization and hence contractionQ7)Tryptophantyrosine metabolism both of them are both ketogenicand glucogenic amino acidsQ8) phosphofructokinase acirceuroldquo inhibitors ATP and citrateQ9)Lysosomal storage disordersjust name and imp charecteristic ans-fabrys and hunters are XR rest all are ARTay sachs-def of hexosaminidase and GM2 gangliosides accumulatefabrys - def of alfa galactosidase and ceramide trihexosideaccumulatesMertachromatic leuko dystrophy- def of arylsulfatase and sulfatidesaccumumalatekrabbes- beta galactosidase deficient and galactocerebrosideaccumulatesNieman pick-sphingomylinase def and sphingomylin accumulatesgaucher-def of beta glucosidase and glucocerebroside accumulatesQ10)S-100 positive slide prognostic factor S100 is a tumor markerfor malig melanoma and imp factor which determines prognosis isdepth of the lesionQ11)Gaucher bone marrow Ans-gauchers cells present which aremacrophages with wrinkeled paper cytoplasmQ12)Young boy with breast biopsy for post-traumatic swelling showingmultilayered cells lining ducts next step maybe this is case of gynecomastiaits mostly noticed by medicalpersonnel after traumaIn most cases no treatment isneededgynecomastia goes away in less than 3 yearsOccasionallymedicines may be used to treat gynecomastia especially if tendernessis a problem treatment includes testosterone gel or surgeryQ13)S shaped bug curved bug curved is vibriodoes S shape alsoinclude in this genus Im not sureQ14) Boy and pet dog both having diarrhea Noovaparasites q15) Scleroderma cause for pulmonary hypertension Ans-PH is highblood pressure in the arteries which take blood between the heart andlungs When PH occurs along with other lung heart or systemicconnective tissue disease (such as scleroderma) it is called SecondaryPulmonary Hypertensionwhen its due to scleroderma the cause maybefibrosisQ16) Pulmonary hypertension patient listed for lung transplantationPharmacologic management during waiting periodmaybe diuretics and oxygen therapylooked up a website which stated epoprostenol(FLOLAN) for those listedfor lung transplantQ17) Vascular bed blood flow increased howz capillaryflow controlled this occurs by arteriolar constriction to maintain aconstant flow in capillariesQ18) Carcinoid lung(some imp features) Bronchial carcinoid tumorsarise from Kulchitsky cells (argentaffin cells) within the bronchial

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

Remembered questions for STEP 1 - USMLE Forum

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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mucosaThese cells are neurosecretory cellswhich belong to APUDsysyemThey have the capacity to synthesizeserotoninACTHnorepinephrine bombesin calcitonin antidiuretichormone (ADH) and bradykininThe clinical manifestations of bronchial carcinoids may arise because oftheir endobronchial or central location their potential for metastaticspread or their ability to produce vasoactive aminesHemoptysis is common occurring in at least 50 of patients Thisfinding reflects the vascular nature of these lesions patients may present with complications due to the neurosecretoryactivity of the tumors Bronchial carcinoids may secrete ACTH inquantities sufficient to cause Cushing syndrome in 2 of patientsQ19)Common cause for cataract and aged skin wrinkles Q20) Retinoblastoma risk for another cancer ans-Some especiallythose in which the tumor involves both the eyes are at a risk fordeveloping other tumors like osteogenic sarcomamaybe due to theradiation therapybut I also had read some where that retinoblastoma patients are atincreased risk of developing some brain tumors( cant reme whichspecific brain tumor)plz correct me if Im wron1Testicular CA drains to para aortic LN2Meckelacirceurotrades is a remnant of vitellointestinal duct3A child with tumor near 3rd vent will present with what sympobstructive hydrocephalus4A pic of carotid arteriogram with arrow pointing to one branch askedfor symp in pt due to its block MIangina symptoms5MRI of abd given asked to identify structure lying in relation topancreas head 2nd part of duodenumbile duct6 While operating for hyper PTH surgeon finds 2 supr and 1 infr lobeto locate the ectopic lobe she has to trace which artery maybe inferiorparathyroid artery

7 Histamine is predominantly released from mast cells

8 Pt has loss of afferent limb of papillary reflex asked to identify thestructure in a cut section aferent limb of pupillary reflex is via opticnerveso that must be the structure asked to identify

9 A neonate is for corrective cardiac surgery to reach PDA catheterpassed from femoral vein must pass throu--Lpulm art LARVRAfemoral vein-rt atria-pulm trunk-left pulm artery-PDA

10 Pt has spastic paralysis asked to locate the area responsible on agross pic of brainspastic paralysis is due to UMN lesionso maybe the pyramidaltractor higher areas in motor or premotor cortex11 If sup mesenteric art is occluded at its origin and no sig collateralsthen which organ is most affected duo ileum caecum colon

12 Pt with seizures and anosmia has which cerebral lobe affectedanosmia indicates involvement of pyriform cortex( responsible forsmell)this is located in cerebellumbut quesasks which cerebral lobeinvolved

13 Hypertensive pt with head injury in lucid later deteriorates brain CTgiven asked if it is epidural intra cereb lucid interval indicates thatits epidural

14 Asked for nerve supply to ant Acircfrac12 of ext ear canalant 12 of ext ear canal-supplied by auriculotemporal npost 12 by auricular br of vagusfacial surface of upper part of auricle-auriculotemporalcranial surface of upper part of auricle-lesser occipitla nboth surfaces of lower part of auricle-great auricular nerve

15 A 21yr male with acute LLQ abd pain amp fever with vomiting whatother signs will be present-tenderness at McBuneys pain on passiveflexion of hip

16 Pt with stone in parotid duct asked for thro which muscle does ductpass to open in oral cavity- zygomaticus major temporalis masseterbuccinator orb oris

17 A druken pt sleeps on arm chair develops wrist drop- nerve radial

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

Remembered questions for STEP 1 - USMLE Forum

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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nerve injury

18 10 yr child with elbow dislocation would also have damage to-Deep brachial art median N interosseous memb brachial v mediannerve injury

19 Microscopic pic of FT with ovum in the process of fertilization plentyof sperms also seen around asked to identify the struc derived fromglycoproteins

20 A girl with well dev breasts pubic hair has normal female ext withtestes neither male nor female int organs what is the cause androgeninsensitvityAdies Pupil Dilated pupil which may react better to near than to light Itis probably due to disease affecting the ciliary ganglion Is hyper-sensitive to any weak Pilocarpine (eg 01) with constriction of thepupil in contrast to the pharmacologically dilated pupil (eg byatropine) which will not constrict There may be an associated loss oftendon reflexes particularly the ankle jerks but there is almost neverany associated systemic disease Over a period of years the conditionis likely to become bilateral and the initially dilated pupil will graduallyreduce in size However its poor reaction to light will continue 2- Marcus Gunn Pupil-paradoxical dilatation of pupils in swinging flash-light testseen in retinal detachmentoptic neuritis etc 3Pupils in pontine lesions- pontine lesions cause miosis but normallight response pin-point pupils following pontine haemorrhage 4central diencephalic herniation causes fixed dilated pupils 5Argyll Robertson Pupil- Accomodation Reflex Present(ARP-mnemonic)

6Pupil in Uncal herniation- findings include ipsilateral pupillary dilationloss of light reflex and ptosis due to compression of cranial nerve III

-Often develops into Korsakofs even when treated

-It has a mortality rate of 70 to 80 if untreated

-The treatment is thiamine 100 mg PO daily for 5 days

-The symptoms include Nistagmus ataxia andopisthotonos

-None of the above

2 Which is the most serious complication of the supracondilar fracture of the Humerus

-A compartment syndrome of forearm

-Failure to heal

-Healing in a non anatomic position

-Injury into the median nerve

-Permanent restriction of the Elbow motion

3 Which one of the following descriptors of adiagnostic test is Influenced by the prevalence of thedisease being tested for

-Specificity

-Sensitivity

-Accuracy

-Positive predictive value

-Reliability

4 A 43 years M admitted for Emergency Gastrectomeypresent confusion on the 3rd post-Op day complains oflack of sleep due to cockroaches on the ceiling he is

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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noted to be flashed amp tremelus by the nurses duringthe day the most likely problem is

-Post-Op Electrolites Inbalance

-Paranoid Schizophrenia

-Depression Psychosis

-Delerium Tremons

-Anoxic brain system

5 Pt with known type II DM treated withClorpropamide present to ED in comma blood sugar =1 mmol L you give the Pt 1 ampule of D50W amp thePt wakes up promptley what is the next appropriatemanagement

-Give another ampule then discharge

-Give 2 ampules then discharge

-Give another ampule then observe the pt for 6 h inthe ED

-Give one more ampule admit the Pt amp start IVGlucose Infusion with frequent ongoing glucosemeasurement

6 Pregnant 36 weeks with vaginal watery discharge management

-do sterile speculum exam

7 Barbiturate withdrawal = convulsion

8 Retrovarted uterus complain = asymptomatic

9 G5 P4 post-delivery postpartum hemorrhage mostlikely cause is

-Uterine atony

10 Anal skin tag in child associated with

-chronic Anal Fissure

11 Child with abdominal pain attacks drowning hislegs up mucouid bloody stool Diagnosis

-Intussusception

12 1st sign of foot gangrene is = rest pain

13 Pt M pain in both lower limbs with week popletialartery pulsation management

transvertebral angiogram

14 basket ball player averted his ankle joint duringjumping at match on Examination Pain with IncreasedVarious range Management

-Repair ligament surgery

-Below knee cast

15 clean wound cut with laceration amp incompletesection of nerve management

-Suture of wound Immediately

-Leave the wound open

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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16 pain on walking increase in 2nd amp 3rd metatarsalbone of forefoot Diagnosis

-Stress fracture

-Sesamoid bone

17 Pt 68 years going to elective surgery he has 4mo history of chest pain amp got same attack at nightbefore the day of surgery what do u do

-Lignocaine before surgery

-Trinatreate during surgery

-Send him for ICU

-Postpone the operation amp check function of thecoronaries

18 collage student F 20 years presented with lowerabdominal pain PE bilateral lower abdominaltenderness febrile Vaginal exam tender withcervical mobilization pregnant test (-) Diagnosis

-Acute salpengitis

-Ectopic pregnancy

-UTI

19 vaginal bleeding stooped at the day of admission pregnancy test is (+) US shows empty uterus amp leftadnexal mass Diagnosis

-Ectopic pregnancy

20 young Pt with history of non productive cough butclinically well C-X ray shows bilateral basalInfiltration Diagnosis

-Mycoplasma Pneumonia

21 Pt with Ulcer in sole of the foot at 2nd amp 3rdmetatarsal joint X Ray necrotic amp destroyed part of2nd amp 3rd metatarsal bone what to do

-Radical debridment

-Above knee amputation

-Daily sterile dressing

-Oral antibiotic

22 Problem which cause most work days = back pain

23 Nicotinic skin patchy is contraindicated in

-Pregnancy

-CVA

-Ischemic Heart disease

-Alcoholic

NB (not sure)

24 Psychotherapy is superior to medication in

-Schizophrenia

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

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-Bipolar disorder

-Alcoholic withdrawal

-Dysthimia

25 mother worried about her child because of historyof myopathy in family what Investigation to be done1st

-CPK

-Muscle biopsy

-Nerve biopsy

-EMG

26 Pt on Lithium therapy became weak lethargicIntolerant to heat what Investigation must be done

-Lithium level

-BP

-Thyroid Function test

27 surgical nurse 25 years old is concerned that sheis loosing her mind for the past 6 months she is beenpreoccupied with contamination on his ward she hasbeen not touching any patient door knobs etc

She was also washing her hand excessively which ofthe following treatments will help in reducing herpreoccupation and hand washing

-Fluxetine

-Lorazepam

-Perphenazine

-Insight-oriented psychotherapy

-Nifedipine

28 M 50 years with Prostatic Cancer with bonemetastasis Treatment

radical prostatectomy

-Radiotherapy

-Hormonal therapy in the form of total androgenicblockage

-IV chemotherapy

29 Pt with family history of urticaria presentedwith urticaria investigation revealed C1 esteraseinhibitor deficiency Diagnosis

-Hereditary Angioedema

30 thickened upper Lt lip with mild vesicles Diagnosis

-Urticaria

-Angioedema

-HSV infection

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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31 Erithematous Vulva with whitish lesion of Candidaof Groin amp Satellite lesions what is thepredisposing disease

-DM

-CA vulva

-Lichen sclerosis

32 Pt with sudden cough amp pain in the Rt side of thechest you suspect aspiration of foreign body what finding of the C-X ray

-Hyperlucent Rt side

33 Defrentiaion between Maxilary amp Zigomaticfractures

34 calculation of the effectiveness of a vaccine

Incidence Non Vaccinate - Incidence Vaccinated

---------------------------------------------------------------x 100

Incidence Non Vaccinate

35 child chalking during eating he becameCyanotic agitated with forceful breathing 1staction to do is

-Hit him from his back while head downward

-Introduce your finger in his mouth

36 17 years F at stage 3 Tanner still not menses management

-Examination of the pelvis

-Chromosome analysis

-Estrogen Progesterone level

-Reassurance

37 asthmatic Pt presented in the ER with Dyspnea used to inhaled salbutamol with no Improvement PEshows dyspnea slit rhonchi at the upper chest amp neck management

-IV fluid + Aminophine

-Coricosteroids Inhaled

-Inhaled Salbutamol + IV hydrocortisone + IV Fluid

38 Alfa fetoprotein Increased in

-Menengomyelocele

-Renal Agenesis

-Down Syndrome

39 pt with abnormal pap smear what is the nextstep

-Colposcopy

40 60 years F presented with 5 x 5 cm adnexal mass management

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

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-Surgery

-Chemotherapy

-Radiotherapy

41 Pt found unconscious on the floor behind the baralcoholic ER agitated semiconscious PE showslaceration on the head all the limbs can be movedall the others are normalwhat is your action

-CT of the head

-IV fluid + Observation

-Discharge

42 Pt fail down from the 2nd floor on his back the following will be part of the Initial managementEXCEPT

-Cervical collar

-IV fluid

-Spine X Ray

-Urinary catheter

43 tertiary prevention is

-Rehabilitation

44 in the ER young Pt treated with Procainamide hisBP decreased to 8060 you tried another time withProcainamide his BP still decreasing what to do

-Benztropine

-Saline perfusion

-Digitalis

-Defibrillation

-Intubation

NB the Pt had Arrhythmia with hypertension (thatacirceurotradeswhy we gave him procainamide) amp because its notdecreasing we have to defibrillate him

45 F 23 years present with fibroadenoma of the Ltbreast in the lower medial quadrant of the breast allare possible EXCEPT

-Give Estrogen

-Give Progesterone

-Fine needle aspiration will bring clear liquid

-Mammography can show abnormality

-1-Child 3years with swelling of scrotum Testis canbe palpated through the swelling Fluctuant painlessObserved for few months Translucent DefinitiveManagement

2- Question on probability- probability of finding onedisease is A and other is B (Independent)Probability on finding the 2 diseases in one pt

a) AX B

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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b) A+BFull term child Birth weight 3000 Developsrespiratory distress Xray shows air bronchogramDiagnosisThe growth of the Tumor following cycles

46 F febrile with tumor in upper Rt quadrant of theanus the mass is painful amp red what to do

hot bandages

-Cold sitz baths

-Surgery

-Systemic Antibiotics

-Topical Antibiotics

47 child with juvenile poliposis possiblecomplication

-Diarrhea

-Painless bleeding

-Painful bleeding

-Malignancy (cancer)

-Non of the above

48 a mother brought hear 12 years daughter whopresent repetitive UTI temp 385 IVP amp cystographyare normal what is the best test to do

-Urine culture

-US amp voiding cystography

-Blood culture

-Cystoscopey

-None of the above

49 fibroadenoma of the breast what is false

-The most common benign tumor

-Fine needle aspiration bring clear fluid

-True solid tumor

-Tumor easy to find because encapsulated

NB check it alone

50 F pregnant 28 years with nocturnal numbness inhands amp forearm which wakes hear up for 3 months she also have difficulty grasping objects what isthe most likely etiology

-Dermatomiosis

-Abruptio placenta

-Multiple sclerosis

-Carpal Tunnel Syndrome

-Hyperventilation syndrome

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51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

51 72 years old with heart failure with high bloodpressure treated for long time He was brought to E Rfor hypotension 8060 HR 110 what to give

-Procaine

-Lidocaine

-Cardioversion

-Digitaline

-Furosemide

52 Post-op of Pancreas what is the cause ofhypovolemic shock

-Initial necrosis of acute pancreatitis has producedtripsine

-Septic shock

-Loss of liquids

-Side effect of anesthesia

NB not sure

53 68 years F with history of Hysterectomy came tosee u because of micturation trouble at effort nodigestive trouble she has a feeling of a painlessmass intravaginaly she has to try twice in order tovoid her bladder what is the diagnosis

-Rectocele

-Cystocele

-Prolapse (Prosedentia)

-Urethral sphincter spasm

-Post-surgical stricture

54 young M feels sudden crack in his calf what isthe best clinical sign to diagnose Achilles tendonrupture

-Decreased dorsal flexion

-Impossibility to walk on the toes

-Increased passive dorsiflection of the foot

-Squeezing calf does not passively planter flex foot

55 farmer 74 years M present with bilateralsemetrical neaurosensorial defenses PE is normal diagnosis

-Autosclerosis

-Professional defenses

-Acustic neuroma

-Presbiacusis

-Circulatory deficit

NB Most common cause of hear losing in elderly ispresbiacusis

56 F 45 years with decreased visual acuity no pain

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no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

Remembered questions for STEP 1 - USMLE Forum

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

no tears what do u exam first

-Tonometry

-Refraction

-Angiography

-Neurologic test

-Rheumatoid factor screening

57 Burned Infant 2nd degree in the upper limb whatdo u do

-Debrid amp skin graft

-Debrid amp bandage

-Debrid amp topic cream

-Clean the wound amp systemic antibiotic

-Local care only

58 Cyclist attacked by bee comes to emergency withhypotension 8060 Heart rate 115 what do u dofirst

-Antihistamine H1 amp H2

-Saline perfusion

-Epinephrine Injection

-Intubation

-IV steroid

NB we also give it by subcutaneous or IM amp inchildren IV or Endotracheal tube

59 child 5 years bitten by the neighbors dog thedog received all the vaccines what do u do

-Observe the dog 10 days amp anti rabbi serum

-Observe the dog amp anti rabbis serum amp vaccine

-Kill the dog

-Vaccinate the kid

-Observe the dog

60 F 28 years present with chronic rhinorrhea inthe exam you found mucousal nasal atrophy diagnosis

-Sinusitis

-Cocaine intake

-Nasal poliposis

-Allergic rhinitis

61 F 45 years back from a plane travel complainsvertigo tenitus moderate hearing loss BP is 160110 Diagnosis

-Hypertensive crise

-Miners disease

Remembered questions for STEP 1 - USMLE Forum

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-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

Remembered questions for STEP 1 - USMLE Forum

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

-Migraine

-Acustic neuroma

-Barotaruma

62 what is the most common cause of lung abscess inpost-Op pt

-Bacterial discrimination from operative site

-Atelectasia

-Pneumonia

man with prior history of recurrent calcium kidney stones ishospitalized and passes another stone which was found to be composedof calcium what do you do as the next step in treatment -choiceswere -diuretics advising the person with diet I think stuff like thatOne of the choices was administering Furosemide which is what Ichose

acirceurobrvbaracirceurobrvbarpic of colonoscopy specimen next to diagram of colon w rectumcircled mentions neutrophils found in crypts--but basically asks for dxI chose ulcerative colitis (crohnacirceurotrades was also a choice)

acirceurobrvbaracirceurobrvbaracirceurobrvbarpt presents w pain decreasing w meals how would test forcausative organism I put urease breath testacirceurobrvbaracirceurobrvbaracirceurobrvbarpt comes in after eating at chinese restaurant feelingnauseous dizzy and some other stuff ques asks what could havecaused this and lists bunch of amino acids I chose glutamate thinkingreaction to MSGacirceurobrvbaracirceurobrvbaracirceurobrvbarfetus is found to have bilateral renal agenesis what otherfeatures would be associated w this I narrowed it down toanencephaly and pulmonary hypoplasia ans is pulmonary hypoplasiawhich I unfortunately didnacirceurotradet putacirceurobrvbar argh

acirceurobrvbaracirceurobrvbarman presents w painful big toe negative birefringent crystalsfound was treated with diuretics for htn I think before this painfulbig toe couldacirceurotradeve been prevented how I put by administeringsomething that inhibits xanthine oxidase (sorry canacirceurotradet remember theother choices)acirceurobrvbaracirceurobrvbaracirceurobrvbarelderly lady presents w increasing difficulty getting up fromseated position find stiffness in range of motion in all directionswupper extremities or something like that and then I think there wasan intention tremor but Iacirceurotradem not sureacirceurobrvbar basically the only 2choices that made some sense to me were Parkinsonacirceurotrades and ALS Iput ALS (unfortunately I canacirceurotradet remember if there was any mentionof cognitive deficits but I donacirceurotradet think there wereacirceurobrvbar sorry again)

acirceurobrvbaracirceurobrvbaracirceurobrvbarCT scan of head showing either crescent-shapedhemorrhage or biconcave disc hemorrhage just know that crescent-shaped = subdural hematoma and biconcave disc = epiduralhematoma and that epidural will have symptoms very quicklyacirceurobrvbar acirceurobrvbaracirceurobrvbaracirceurobrvbarProblems w UV-light are caused by deficiencies in DNArepair (right)acirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPt w myasthenia gravis whatacirceurotrades the effect on thepostsynaptic neuron I put something like decreased EPP orsomething like that other choices dealt w amplitude in presynapticpostsynaptic neuron

acirceurobrvbaracirceurobrvbaracirceurobrvbarDeficits from damage to cerebellar vermis vs hemispheresacirceurobrvbaracirceurobrvbarLesion is found on ventral root at L3 deficits would be seenwhere At L3 below L3 above L3acirceurobrvbar I think I overanalyzed this one acirceuro˜cause I put below L3acirceurobrvbar Iacirceurotradem thinking it was at L3acirceurobrvbaracirceurobrvbaracirceurobrvbarQues about differentiating pancreatic cancer from cirrhosisacirceurobrvbar acirceurobrvbaracirceurobrvbarPt has one kidney removed to donate to relative for transplant6 weeks later what will GFR be Choices included decreased by 1020 etc or no change acirceurobrvbaracirceurobrvbaracirceurobrvbarMother finds out she must deliver fetus before termsphingomyelinlecithin ratio is low administering what will help babyAns was glucocorticoids I think

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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acirceurobrvbaracirceurobrvbarCouple are both carriers of hemoglobinopathy hydrops fetaliswas found in baby what will RBC morphology be like I put microcyticacirceurobrvbaracirceurobrvbaracirceurobrvbarPt found to have positive osmotic fragility test may havelisted some other stuff but I put dx as hereditary shperocytosisacirceurobrvbaracirceurobrvbaracirceurobrvbaracirceurobrvbarPic of foot w tendon torn that attached to lateral aspectof pinky toe which muscle was affectedacirceurobrvbaracirceurobrvbarx-ray of hand w sharp object piercing between 4th and 5thfingers which artery was affected acirceurobrvbaracirceurobrvbarpic of an Ig asking which region is the constant region andvariable regionacirceurobrvbar sorry

acirceurobrvbaryoung child presents w recurrent infections w saureus andaspergillus negative nitroblue tetrazolium test had all immunityinjections norm antibody levels this is deficiency of what I think I putoxidase deficiency acirceurobrvbarin fetal circulation travelling from umbilical vein to heart throughwhich do you need pass I put ductus venosusacirceurobrvbaracirceurobrvbarin pt observe medial border of scapula protruding when patientputs arms against wall which nerve is damaged Long thoracic nerve

acirceurobrvbaracirceurobrvbarpt w inability to use left arm show pic of humeral head wtendon retracted from top of head which muscleacirceurotrades tendon was thischoices included suprasinatus infraspinatus teres minor teres majorand biceps I think the answeracirceurotrades supraspinatus

acirceurobrvbaracirceurobrvbardamage to recurrent left() laryngeal nerve will lead toweakness in what acirceurobrvbarhiatal hernia might also affect which structure passing throughthe diaphragm nearby Thoracic duct and azygous veins were choicescanacirceurotradet remember what I choseacirceurobrvbaracirceurobrvbarPt presents w infiltrates in lungs able to tell from exam whenlistening to lungs in left (or right) mid-axillary line which lobes areaffectedacirceurobrvbarWoman undergoes c-section after procedure canacirceurotradet stopprofuse bleeding which artery may have been severed

acirceurobrvbarPt has poor repetition good comprehension and I think difficultyrecognizing fingers or something like that qs asked for which area ofbrain may have been injured looking at 1st Aid Iacirceurotradem thinkingarcuate fasciculus

acirceurobrvbarQues involving internuclear ophthalmoplegia acirceuroldquo woman hasdifficulty w lateral gaze and canacirceurotradet converge eye that has difficultyw lateral gaze which muscle was affected Ans related to SO4 LR6Couldnacirceurotradet think of that mnemonic when I was taking the exam

acirceurobrvbarPt undergoes surgery and falls into coma w chance of normalsurvival very slim no advance directives upon speaking w familyfurther physician finds out that pt did not want to live in persistentvegetative state doc then terminates life support what kind of decisiondid physician make Choices included decision from limited resourcesand some other one

acirceurobrvbaracirceurobrvbarObese woman is chronically tired husband reports that she isvery loud snorer canacirceurotradet remember rest of the ques but somethingto do w sleep apnea may have been dx quesacirceurobrvbara ques involving narcolepsy and what kind of hallucinations areassociated w the conditionacirceurobrvbarQues involving delirium acirceuroldquo after surgery patient is in and out ofconsciousness hallucinating and having illusions

acirceurobrvbarChild is constantly creating trouble in class bullies other kidssometimes will be able to be sustained in task where he has interestthough dx I think I put conduct disorder but Iacirceurotradem not sure if thatacirceurotrades the answer

acirceurobrvbaracirceurobrvbarEating disorder quesacirceurobrvbar canacirceurotradet remember if it was anorexia orbulemia but the question was asking for what could be a condition inthe patient a lot further down the line in the futureacirceurobrvbar I think I put jointproblems or something but I canacirceurotradet remember what the otherchoices wereacirceurobrvbar I just had no idea

acirceurobrvbaracirceurobrvbarWhenever child cries mother gives the child a treat to quiet himdown what kind of reinforcement is this (or something like that)

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

Remembered questions for STEP 1 - USMLE Forum

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

Remembered questions for STEP 1 - USMLE Forum

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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orotic acid which pathwayalbright synd whr is the defectturner synd how to concievehcgivfmutation in hyrophobic signal sequencewhr will be productsaccumulaterer endosomeant spinal artery occlusionarnold chiarithrombosis in MGN wat cozdentine dyplasia whr protien accumulategenetic imprintingreyes synd patho in braindamage to cellular mitopraider willithynic tumorpic of lacerated wt type of woundtearing woundpleotropymoa of azathiioprinmom o negbaby o pos fathers blood typea pos or o neg

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

---A pt with Turner synd Ask you about getting pregnant What do youadvice her Oocyte transfer IVF---Patho slide with given vignette Hypertrophic Cardiomyopathy MCC ofdeath Arrhythmia--- Vignette a young woman with high fever septic condition INRincreased fibrinogen decreased etc Answer DIC ---Two TTP question on different block--- wWd dhat do you give him after desmopressin Cryoprecipitate---Warfarin overdose---Squamous cancer of lung with hypercalcemia Ectopic PTH---PT with numbness and tingling on dorsum of foot ankle reflexdecreased where is the lesion L5S1 disc compression

pay attention to HIV drugs

1- 21 alpha-hyroxylase def2- prolactinemia lactationacirceurobrvbarpt not pregnant3- pt gone 3 months without menstruationacirceurobrvbarDx Pregnant4- Pt with Turner Syndrome streakacirceurobrvbar45XO5- Erecrtion problemsacirceurobrvbarwhat venous sys affected6- Pt with Infertility problem7- Huntington trinucleated repeat8- Non-communicating Hydrocephalous Gross pic shows block between3rd and 4th ventricle9- Remember where spinal pathways crossesacirceurobrvbarmedbrain 10- Iron Def pt c hypochromic microcytic decrease iron stores in bonemarrow11- hyperpigmented neutrophil(pic) pt with neurologic def acirceurobrvbarB12 def12- Pt on vegi dietacirceurobrvbar B12 def13- Pt Sleepy during the day Dx Tx acirceurobrvbarSleep Apnea

had a lot of ct scans and Mribut one thing I will emphasize thatbasic is critically important eg gen pharm and gen patho is must qs about comp inhibitor with graph lots of lines crossing and had toidentify the comp inhibQ about efficacy of drugs on graphq about bony defect on the back of newborn with tuft of hair onit=spina bifidaagain q about meningomylocele asking contentshirshprung disease whts the cause of disease=failure of neural crestcell to migrateq about 40 yr old with 20 yr HO type2 diabetes tingling and sensory

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prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

Remembered questions for STEP 1 - USMLE Forum

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

Remembered questions for STEP 1 - USMLE Forum

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

prob in limbs=pripheral neuropathyoung women with sudden knee joint swelling= trauma( septicarthritis was also given but it was asking sudden)occulomotor lesion in at least three qsmidddle cerebral artery lesionMRI of sp cord =subacute combined degenerationpt has accident and lost conciousness after 18 hrs type ofhamorrhage was askedq about dysphagia even for liquids =achalasialots of neuroanatomymen1 =ret gene diabetic keto acidosis= what happen to oxygen dissociation curvehad to identify on graphacid base balanece graph in person with resp problemtension pneumothorax signs and sypmtomps were given with Xraybasal cell ca best treatment optiongranulation tissue what day of wound healinga lot of immunologygenetics with konckout miceevery block about 3 doc pt relationWaldenstorm gglobulinemiagfr and rpf with efferent art constthyriod was asked the most in endo

X-ray shown there is an artery on the right side and asked about it peronial nerve easyshowed all the bracial plexues and asked to identify the nerve thatgetes effeted if there is a humurs neck is fraturedVertical deplopiacirlcel of willis diagram and asked which artery effected if the personlegs are affectedmajor drift in influeneza and asked how it occuredA child has dermatitis since he started new school adn he rides hisbikes to school and also plays in football feild after school anddescribed as contact dermatitis and asked i1 caused becos he sweat when he is rides the bike2 poison ivy form play gound3 on the way to school becuse of sun i think it wasA man gets into an accident he had his 6 years old sun wiht him in thecar boy got contution on his head a some other injuries asked was the boy on front seatwas he wearign a seat belt some ansewers liek thatYou and a anesthalogist something about gestric surgery andanestahogist said somethign about man being fat do you talk to him in privattalk to him when witness presantdo nothingtake him to the commitePku the boy is put on a diet and phenylalanin is under control what elseshould to test him forLysch Nyhan describe 7 years old boy self mutilation mentalretardaion what some enzyme si missing and wht will accumulat UricacidMcardles disease no increas in lactic acid when the girls excersisesmyophorylase

A woman has rohmatoid arthritis she is given perdenosin then you incthe does started to feel really weak predinosin side effectchronic rohmatoid syndormsome other choicesDescribed a man he had a strok showed 2 picture then he started tosee some changes did say much about where and said one pic from 9month ago one from nowand said what part of body t effect and where

Seborrheic keratosis stuck on appearance of this verrucoidappearing pigmented lesionA woman taking ACE inhibitor has a dry cough which other medicationwould you give heirLosartan

A 55yo man came in to you clinic he had blood in his unrine hisprostate is enlarged and firm and there is a mass above his left

Remembered questions for STEP 1 - USMLE Forum

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

Remembered questions for STEP 1 - USMLE Forum

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

Remembered questions for STEP 1 - USMLE Forum

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

Remembered questions for STEP 1 - USMLE Forum

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

Remembered questions for STEP 1 - USMLE Forum

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

Remembered questions for STEP 1 - USMLE Forum

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

Remembered questions for STEP 1 - USMLE Forum

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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kidney Smoker fro 34 years Whats your diagacirceurobrvbar1 pyelonephritis2prostitis3 renal cell Ca35 years old came in complaing that her shoes donacirceurotradet fit heranymore her jaw wideneda nd there is gap in her teeth whathormoned is responsible for this1 somatostatin A2 prolactin3 eastrogen4 GH5 LH3 A 34 years old and her husband come in to the clinic they want tohave a kid the woman cannt get pregnant there is nothing wrong withthe woman and her husand all the level of hormone are normal whatcannt she get pregacirceurobrvbar1 I piked a choice where it said somtheing like she is PID in the past4 A nurse came in with palpitation complain god anxiety heatintolerance and she admitst that she is taking some pills to loseweight and values of TSH T4 and T3 and given you dia1 Hasimoto2 factitious disorder3 primary hyperthyroidis3 Hypothyridism5 A woman pre described having polyhydamnios whats risk in kid1 Renal agensis2 Esophageal atresisasomother choieces6 A man came in with H pylori you gave him proton blockerwhat is the PH in of stomach something like that

A woman came in with bloody diarrhea for 5 days no travel history shejust got a dog and the dog like to lick her face organism causeign thediarrhea1 Ecoli2campylobacter3 Yersinia pestis

A man who came from berzil had PPD negative then he has meseals ayears later his PPD was positiveMOA how it was positive

How does N gonorrea cause the inf 1 Endotoxin2 capsule3 pilus4 flagellum5 sporesDescribed Actinoyces it was easyHow do you differentiate spcies with in Streptocouccus something likethat1 coagulase 2 catalase3 hemolysis

A older man came in with pneumonia he recived tetnus vaccine 5years agoWhich vaccine should he be given

Osteoyelistis the described in a kid what sickle cells

Over expression of TNF- Alpha what will it cuuse in a mouseMAC formationDec macroghages and IL-2Dec T lymphocytes

A child got into accident and needs blood transfusion he is has Ig A defwhich of the blood is contraindicated in himA normal personsSomeone with Ig A defAnd somother choices I donacirceurotradet remember

MOA how methicillin causes Interstitial nephritisA man taking procanamide get Lupus but it was a long Q give all sort

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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of infHow does a organism becomes resistant to Amoxicillin Cephlosprinsand notAminoglycosisdes

A 18 years old develops rash all over his face after he started a newacne medication he has a sore throat and is also taking Medicaiton forthat then they gave some names of AB he is taking and one of themwas Tetracyclines so I picked that

A man has Aid and is infected with Pneumocytis carini and he wants totake something for proflaxis1 Ramfipin2 TMP-SMx

A man just had PPD positive the drug with wich MOA should he be giveI picked dec synthesis of mycolic acid

A girls just developed dertophytoses she is started on Terbinafin MOAof this drug1 Inhibit fungal enzyme squalene epoxidesA man with aids developes CMV he is given a medication MAO of thismedicartion

A man who have had a depression problem for past 10 years and tried2 kill himself on two occasions is broght by his neighbors because hecannt sleep he think his neighbors dog is in the you clinic and is goingto bite you what medication would you give him Atypical antipsychotic pluexetine amitriptyline benzodiazephines

A boy is havig sezures and described it was partial complax A man come in he is being treated for depression Name of medicationthat is causeing urinary retention tachycardia etc I put amitriptyline

A man got in to an accident broke a lot of rib bone and leg bones hegive pain medication (morphine and lorazepam) and after 30 min he isstill in pain1 Medicaiton is has short half life2 increasead intolerancesom other choices

A man is on clopidogrel is should sid effect Neuropenia

A man is under chemo why is allopurinole added to his regmineinhibits uric acid formation

A girl comes in with inflammation of medium-sized muscular arteriesinvolving renal and visceral she is also positive for HBV next step sheis in pain cyclophosphamide and coricosteriods werenacirceurotradet in choircesit was all the antinflammatories

A manacirceurotrades hand were shown and Raynaudacirceurotrades diseasse wasdescribed what else he has PSSDescribed Kayser-Fleischer ring and asked where is copper beingaccumulatedTension Pnumpthorax explained and gave 5 xray and asked to pick one Epidual hemaotomaPic of diardia lambila shown and aked what it cause bloody diarrheamalabsorption

Guys I Had atlead 15 Q just on 2nd messenger there is a page in FirstAID G-protein linked 2nd messengers Know it well There were oneline Q and confusing

Described a child with maple syrup urine disease and asked whatVitmin should be given to him Also child with led poisoning what is accumulated in urine3 quesiton on Vit B12 asked what is in urin if def

A boy with I dotn remember with what but if his spleen is remobved hewill be susceptible to what kind of infectionsTransduciton descried

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

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A 25 y0 girl whith disseminated diseas with the constitutionalsymptoms rash on palms and soles Described VDRL FTA-ABS medthod and asked about which one ispositive I ma not sure A man is acting strange otherwise healthyand some an organism isfound in his temporal lob 2 Q on influenz virus and vaccineWhat is nevever normal in a person flora staphylococcuss viridianstrep TB EcoliA12 diabetic boy is not taking his not taking is medication regulary 1 involve in actively and dicuss with mother some choices like thatvery confusingA 34 y0 college of you has strep throht he asked u to give him somesample AB if you can because he is really busy and cannt see hisphysican You response should be1 acirceuroœdo you think its strep throatacirceuro2 I m sorry you should see your physican3 I will give you a AB until you see you physian4 I will give penicillin for 10 dayHow does cholestryramines work

A long Q about a man with high cholestrole and asked about whichmedication acts also like an anoxident

Described Torsades de pointes and asked about the medication causedit Sotalol was in the choices

Also gave Arachidonic acid sturcuter and asked where does asprinworkd very werried QA man has asthma diabetes and hypertention what is contrindicatiedAlbutrolPropnololCromolynThrophylline

How does Tomoxifens work they didnacirceurotradet give he name but descriebeditWhy is mesna given along with cyclophosphamideRenal cell Ca slid is hown and asked for risk factor I put smoking itwas a har Q because they just showed the pic and said what cause thisthe slid was form Goljan so I knewGuy I had 10 Q from breast ca I coundted all of them all slid wereshown I didnacirceurotradet really study breast ca and all of those are in goljanslides I just saw and know as goljan the location very hard Q and alsoasked about prognosisAlcholic with pancreatic adenocarcinoma pain readiating ot backShown x-rya and asked which of these is x-ray of a person withrestrictive lung disaesAlso 1 Q about Emphysema described itA q about a girl has high ammonia concentration OTC def

Interssusception which seg most involvedMuliple myeloma guys you had to know it by looking at slide and saidwhat would you see in urine of this person Hurschsprungacirceurotrades disease what would you see in the intestinal biopsymissing ganglionDescribed Gout and asked what kind of crystal would you cHemophila A confusing QDIC 2 Q

Hyperaldosterinism in a child it was very very confusing QAddisionThymus missing what other sturtuer would be missing in this personPTH is inc and phosprus dec yWoman has polycystic kidney diease she at most risk of which cancerOvarian cervical someother choicesHydatiformole in a woman was found 6 months ago now she presentswith basically they described coriocarcinoma

Non communicating hydorceplus showed tumer blocking 3rd venticaleWhich hormone is involved directly in formation of polycycyctic ovariansyndrome LH FSH testestron estrogenEctopic pregnany describedHomeboxe gene abnormalties

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

Remembered questions for STEP 1 - USMLE Forum

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

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Something wrong with Androgen-bindig proteins problem with whatsertoli cell leydign cells testosterone Co2 transport in tissues what form is it in peripheral tissueBicarbonateA Q about inc in Vita min D and what happens to ca pth phosphateRicket described in a child asked what caued itAns another Q about Ricket what kind of bone would you COne Q how does bone get nutrientsSame Q form UW if you constrict efferent arterioles what happens toRPF GFR FFAlso q form UW 3000kcal and 30 from protein 200Q with a women with diabeties has renal problem what medicationshould she be give to slow progression ACE inhibitors ansQ about baroreceptors dotn remember exactlyPDA murmur describedAn other one about senile purpura in old man not palpable describedsenile purpuraA child has meningomycelocele what else would you CShow 5 slide and asked which slid is sertoli cellsAdenoma polyp showed and asked for diagDescribed a man with burkitts lymphoma asked what when worngTranslocation I got this wrong I was thinking apoptosis I donno b Ihouth it was follicular Def of pyruvate kinase what would you c in urineHurler what is accumulatingPetigery of Muscular dystrophy very confusing ans Skew X promble Iput everything else didn tmake senseWhen insuling inc what other hormone inc I dotn remember the QA diabetic pt comes in he excersies he is taking care what is complientwhat else shold you tell him I put check you feet everydaySarcodoiss Q very long and confusingColon cancer APCBillary cirrhosis in a womanA man with hepatocellular ca inc PT time what would you C AFB

1 what kind of receptor on bronchi beta adrenergic Muscurinic receptor

2 bicornu uterus is due tofailure of fusion mullerian ducts

3 chornic pain syndrome where is the defect460ho head injury 10 year back recurrent rhinorrhea whats findingon CSFIf no infection normal CSF5ho radiation exposure in neckwhat cancer would developePapillary carcinoma of thyroid6what make unconjugate bilirubin water soluble--conjugate

7 something like that in my exam as part of reserch by medical student cardiac cell has Ap of + 60 mvfirt time and + 30mv second time why its decrease in secondtime a student add more Na+ outside cellb student remove the Na+ from outside cellc student add more K+ inside celld student remove K+from inside cell

8 withdrawal from which of the ff substances is most likely to producea life threatening syndrome in a person dependent on that substanceA amphetamineB cocaineC heroinD MethyphenidateE secobarbital

9 clinical trials have suggested that retinoic acid can induce remissionin pxs with acute promyelocytic leukemiasuch remission is related tothe abilty of retinoic acid to promote which of the ffA differentiation of leukemic cells

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B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

Remembered questions for STEP 1 - USMLE Forum

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

Remembered questions for STEP 1 - USMLE Forum

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

B diffrentioaation of monocytes into macrophagesC generation of cytotoxic T lymphoctesD Production of interferonE repair of DNA

10 42yr old man with pnuemoccal pnuemonia has acute fibrinouspleuritiswhich of the ff proteolytic neymes is required to eliminate ttheexudate and restore normal anatomya collagenasesb stromeolysinc plasmind thrombine trysin

1Tx of dermatophytosis2Malaria Qlike an asian immigrant with remittant fever chills3Anemia Blood picturemeaning cell counts amp all parameterslikeMcvHctTibc4An interesting Xray which actually looked like Situs inversusbutprobably wud have been taken with pt in a prone positionie on histummy 5role of GAB A in psy

Acellular lesion - diabetic nephropathySpecific site of AG toxicityret gene association - which cancer - as a part of a vignetterecycling of Pyruvate - lactate - Cori cycle - enzyme inhibition whathappensnew kind of osmotic diuretic --blah blah - just plugged in mannitol and Iwas ok - asked for sethiazide and digitalis - sepic of splenic infarctcorticosteroids and adhesion molecule synthesis in the form of graphsMOR for aminoglycosides - case scenarioSerum Na - Legionellaalpha 1-6 - debranching enzyme deficiency - shrouded in a scenariowhere there was labelled substrateesophageal manometry of sclerodermaS100 antigen - melanomapic of basal cell carcinoma - risk factor in womenglyburide seS-S bond important in nephrinbeta MSH - skin pigmentation - case scenarioclos botulinum Werdnig hoffman - comparison scenario

1 po260 pco2 55 Hb 15 whats the p502 MOA ATP on allosteric enzyme3 what kind of receptor on bronchi4ho polychythemia whats change on red pulp of spleen5MOA of superantigen on septic shock6 mutation on CAP 7 length of mRNA is determine by what 8 unlar nerve injury9middle ligament calcification on x-ray10cervical ribs on x- ray11common perioneal nerve injury12 lekage of amniotic fluid case potter s syndrome same as bilateralrenal aplasia13 volvulus11 colon cancer 12 bicornu uterus is due to 13 ho recurrent gonorrhea what the complication after 10 year 14nucleus of teste on fig 15 medial lemniscus on fig16 find corticospinal tract on medulla17 chornic pain syndrome where is the defect on CT18 epidural hematoma which arterisCT19 lateral rectus muscle on saggital view on MRI20L5_ S1 herniation21 disc degeneration22 ho child abuse and child die whtats the pathology on spinalcord23 h o parkinson where is the lewys bodies located on fig

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

Remembered questions for STEP 1 - USMLE Forum

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

Remembered questions for STEP 1 - USMLE Forum

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

Remembered questions for STEP 1 - USMLE Forum

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

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76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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24 XII nerve injurywhats the finding25 411 translocation i think its AML26 pericardial fluid where shoud we put needle to drian fluid271122 translocation whats the defect on heart28 mitral stenosis case29 aortic stenosis case 30 singla S2 heart sound where is located on graph 31 ventricular tachycardia on ECG32 cerival biospy cell have high nnuclear cytoplasm ratio but donot invade the basal membrane CIN33separation of chromatid which phase 34 benifit of circumcission35 persistant vatilline duct36 zero orderkinetics37 h of taking digoxinwhats chage on ECG38B27 relation39h o COPDright shift curve in graphis due toincrease co2 2 3BPG40budd- chiari syndrome41 case of endrometrosis42 HTN patient die suddenly where is the lesion on brian43case of fibroadenoma brest44 case of brest abscesswhats the common bug45mutation on TATA box46 anticodon was given write the codon47digoxin toxicity in old age is due to48MOA of amphotericin B49 MOA of vinblastin50 Se of bleomycin51vit that given with methotraxate is52compatative inhabitor on graph53se of gancylovir54 s e of AZT55 MOA of anstrazole56MOA of sulfonylurea57neutrophil migration is determine by what 58 s e of malaria drugs59case of aseptic meningitis whats the finding on CSF60ho head injury 10 year back recurrent rhinorrhea whats finding onCSF61gulf player weired mole on lower leg whats the risk factor 62case of neurofibromatosis63clean wound on fig whats the healing process64 ho alcohol taking patient is hypoglycemic 50 dextrose isgiven but patient still vomitting what s the next step ofmanagement 65 whats effect of alcohol on gluconeogenesisi66celiac sprue duodenal biopsy done whats the other labfinding antibody to what67 case of rota virus68 case of measles 69 case of cerebral malaria70 case of streptococcus pyogne PSGN71 case of styphi72case of meningitis 72 case of vWF defeciency73case of follicular lymphoma74case of AML75 ho radiation exposure in neckwhat cancer woulddevelope76 embryo derivative of thymus which pouch77 ho autoimmuno disease remove the thymus78 ho die in utero in 22 weeks whats defect oncytogeneticsthey give placenta picture 79 case of turner syndrome80 prevalance is 1 39000 whats the heterogygote frequency of child81 weired pedegree i still dont know what they asking 82 epithelial lining of ureter83 mutation HMCII84 Hb 5 polysegmented neutrophilpatient is dyspneawhats thenext step of management give boold or vit B1285 Hb7 microcytic anemia whats the next step of managementmeasure ferritin or give iron

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

Remembered questions for STEP 1 - USMLE Forum

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

Remembered questions for STEP 1 - USMLE Forum

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

Remembered questions for STEP 1 - USMLE Forum

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

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86ho poor nutration fatty liver what s the case 87 what make unconjugate bilirubin water soluble88stone on ureter whats effect on GFR89left renal a stenosiswhats effect on renin level90 blcok the PTH recepter on kidney whats effect on PO4+ caabsorption on GI 125 dihydrocholicalciferol 91hyperthyrodismwhats TSHT4T392 graves disease antibody to what 93 anorexa nervosa whats the FSH estrogen level94 estrogen produce by which cell 95 spiderangioma is due towhat excess on blood96seminoma lymph drian in where 97 h o hernia in early age what defect 98 left testicular vein drain in to99 h o abortion on 12 week beta_hCG increase what producebeta_ HCG100 MOA of Aspirin101 MOA of iburfen102 conjoined babywhat is the number of placenta amniotic 103 ho sudden headache bood in CSF whats the the cause104 case of temporal arteritis105 pathological finding on PAN106pathology change after 48 hour in MI107 DOC acute gout107color of fluid in acute gout 108NSAID resistance acute goutwhats the next DOC109recurrent kindey stone which amino acid should add indiet110suger burn smell in urine which amin acid metabolism defect111whats the case of anemia in lead poisoning112 + glycin -------gt hema113ho insulin producing tumor glucose is 20 whats the effecton fasting they give whole glycolysis chart 114warfarin toxicitynext step of management 115 second messanger on hemorragic shock116 how many glucose need to produce one fatty acid 117ho epigastric pain does not responce to pain medicinewhats the next step of management 118 site for peritoneal dialysis119 case of BPH120 case of cor pulmonale 121 size of partical that can remove by mucocilliary mechanism122 ho pacemaker replacement does PR interval alwayssame123ho chines pharyngeal carcinomawhats the case tobaoor EBV124 pathology change on acute rejection 125 h o DM they give both kideny an ask what s the pathologypapillary necrosis126 case of transitionl cell carcinoma they give 6 fig of urinarysystem with different shape and size and ask which one is due totrasitiona cell carcinoma127 case of delirium 128 case of schizhophrenia129 case of displacement 130 case of VSD131 nurse give ho hematuria and back painthere is noassotiation between pain and hemature later she threat to sue todoctorchoices is facticious antisocial133 patient came to ur office with his dogwhats ur responcebefore he enter the examination room134ho diarrhea an vominting whats the MOA they give new bugsomething hydrophillia135 case of H influenza136 8 year kid h o asthma patient do not want to quite thesmoking so whats the next step of advise regarding tosmoking140 ho anurea after riding bicycle (saddle injury ) where is thelesion141 drugs work in dista tubule142 damage of pituitary stalk what increse143 antipsychotic drugs work in which receptor

Remembered questions for STEP 1 - USMLE Forum

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144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

Remembered questions for STEP 1 - USMLE Forum

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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ReRemembered questions for STEP 11119522

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Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

144 moa of BUSPIRON145 ho hemorrhoidswhats the DOC 146So TCA147 h o depression after surgery whats the DOC148 case of Osteogenic imperfecta149case of mycoplasma pneumonia150 h o seizure multipal calcification on CT subcutenious ovalshape bumpso whats the bug151 75 year old man lower back pain osteoblastic errosionwhats the case of pain

everybody calm down and pray for peace for the world Ok No hateand no dirty words to each other OK We are all bothers and sistershaving the same dream to become a doc and one day to help othersand yourself

Ok my contribution more precisely it is math3s contribution I put allof her qs together so it will be easier for you to read and to benefit

-------------------------------------------01 which one of the follo cause asthmacockroach spidermilliedecentipedetermiteshttpwwwniehsnihgovairbornepreventroachhtml

cockroaches is the answer

1 visual problem and prolactinhypothalamus orinfundibulumchoose infundi

Hyperprolactinaemia caused by compression of the pituitary stalk(infundibulum)

Hyperprolactinaemia may be caused by either disinhibition (egcompression of the pituitary stalk or reduced dopamine levels) orexcess production from a prolactinoma (a pituitary gland adenomatumour)

2 for terminationg pr synthesisatpgtpcgmpcatpfor terminatin protein synthesis energy req in the form of atp no its gtp

The mRNA Signal STOP Codons UAA UAG or UGA There are no tRNAs that recognizethe STOP codons UAA UAG or UGA ----Soluble Protein Release Factors RF1 responds to UAA or UAG RF2 responds to UAA or UGA RF3 a GTPase (like EF-Tu and binds in a similar A-site location)RF1RF2 interact with RF3-GTP have a similar shape as EF-Tu-GTP-aa-tRNA or EF-G and bind in a similar ribosomal site (A-site) In a mannersimilar to EF-G GTP hydrolysis drives the movement of the terminalmRNA codon into the P-site moving the last tRNA into the E-site andoff At the same time the polypeptide chain is released after hydrolysisof the tRNA-peptide bond In eukaryotes only a single release factor eRF is necessary Itrecognizes all three STOP codons and interacts with GTP A mutation resulting in a premature STOP codon is called a nonsensemutationElongation consists of three distinct steps to add one amino acid Requires three elongation factors EF-TuEF-Ts and EF-G Requires two GTPs per cycle (4 phospharyl bonds)Occurs many times per polypeptide The elongation cycle is similar in prokaryotes and eukaryotes Fast 15-20 amino acids added per second Accurate 1 mistake every ~10000 amino acids Termination results in the release of the polypeptide chain Requires one of the three STOP codons UAA UAG or UGA Requires RF1 or RF2 and RF3 in prokaryotes (eRF in eukaryotes)

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

Remembered questions for STEP 1 - USMLE Forum

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c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

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but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Requires one GTP Each step of protein synthesis (initiation elongation and termination)requires GTP 3 in aat defic in emphysemadefect in lower lobe

4 hi guys back from examwhat to sayit was verytough15straight forwardless from uwasked aboutt -tublesurea into waterand a lot of other stuff in a very confusingwayhad barely time to finish completngneuroanatomy waseasyand also geneticsfew pharmavery confusing doctor-ptrelationship

The Ca which causes muscle contraction is stored in the sarcoplasmicreticulum i thought it was t -tubulesi choose Sr

my exam was tougher than usmle structure of tyrosinetracheso-esophagel fistule=proximal eso blindi knew this a lot of options tomake u wrongca channel=L typei knew thiswent wrong onT tublesdont know about ATP muscle contractiona lot of confusingoptionsprimary lung tumor in asbettoseasked if it was inbronchibronchiolesaveolietc

5 pain anlog med NE5-HTgabaachi got wrong on thisis NE=amytriptyline for pain

math3 - 032107 1448Gabapentin (brand name NeurontinAcircreg) was initially synthesized tomimic the structure of GABA for the treatment of epilepsy Nowadaysgabapentin has been widely used as a medication to relieve painespecially neuropathic painthanks i choose GABAi thought iwaswrong

anout pain yes you are right it is NE via alpha 2 could be alsoanalog of glutamine receptors Mu receptor

6 pulsating abd massartherosclerosis or marfani chooseartherosclerosis

7 guys what is 7 methyl guanosine its cap for 5 end of mrna duringposttranscriptional processing of mrna

8 glands +chondroid celll adenoma adenocarcinoma chondroma chpndrosacroma teratoma

something has both atypical glands +chondroid cellsichoose teratoma I think questions is basicly saying there are 2 differenttype of germ tissue

you are correct math since rest of them it would be only one origin

9 36 atp for cellelar respiration of glucose

depends which transport they used malate or G3Pmalate transport would give you 38G3P shuttle transport would give you 36

choices were 261436

10 anatomic snuff box carpel bone scaphoid n trapezius form thefloor

11 increased intracranial pressurevit excessvit a

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

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12 st corneum clipped offwhat will depositi chose keratin uriteseems like psoriasis what were the choices for the st corneumques

Cells of the stratum corneum contain keratin a protein that helps keepthe skin hydrated by preventing water evaporation In addition thesecells can also absorb water further aiding in hydration and explainingwhy humans and other animals experience wrinkling of the skin on thefingers and toes (colloquially called pruning) when immersed in waterfor prolonged periods

13 which aa deficit in kwashiorkor options wereglycineglutaminealanineaspartate

no these were the only 4 optionsi was going to and fro on this

14 another acute toxicityparaniafear options werepcpheroinebarbituratesbenzo

yes its pcp

15 tyrosine precursor of dopaminethey gave 4 chemicalstructure

16 during seizure where is the problempremotor primary motor

42 The premotor seizures

Seizures from the premotor areas are mainly characterized by tonic andpostural phenomena predominant in upper limbs with adversion whichcan be contralateral or ipsilateral and symmetrical or asymmetricalWhen there is a propagation to the primary motor cortex clonic jerksmay be associated with the seizure

17 kasmala i can not belive they ask me the same qs like what happen if u add the ATP during muscle contration

a myosin attached with actin b myosin separate from actin cdbut i chose bbbbbb myosin separate from actin

for muscle contractionthere were long choicesi chosedephosphyr of myosin when atp is boundi dont know if i am rightkashmala there were no time to differtiate with the choicesthechoices were all long80of q were to mis lead uor asbettose they told he hadmesothelioma and asked where is the primaryneoplasmpleurabronchialveoli ETc

18 what prevent urine going into abdominal cavityis it transversalisfascia for myosin there was only phosphorrylationno dephosichose phosphory another q on insulin was dephosphorylation

dont remember exctaly but something like this In eukaryotes during mRNA post translational modification some part of rna is removed whatyou called ita) Exonb) intervening sequence

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

c) dna fragment and one more option

2) This one is one hoxthe child is born with six fingers in both hand and his 4th and 5thfingers are fused together he has no other abonrmalities what geneproblemi didnt remeber all option but some of them are1) hox b92) pax c3 and some other options that start with other hox

1pansystolic murmur(ASDVSD PDA)2transposition OF GREAT VESSELS(ho 1day old baby cyanotic)3staright easy qs abt deliruim4ho holo systolic murmurans MIT REGURGITATION5a baby born and died (mother has ho oligohydroamnios) inautopsy kidneyagenesiswhat other findingans pulmonaryhypoplasia6 aortic regurgitationit was an easy qs7ho autoimune hemolytic anemiapostive combs test was thereitwas straight qs actually8ho 3 pain one sexual prob thou it was big history anssomatization disorder9a women she always in hurryworry abt lot of things abt her parentsabt kids and call her hubb that he safely reached his officeansgeneralized anxiety disorder10 ho ADHD ASKING ABT MEDICATIONI CHOOSEMEtAMPHATEMNIE11MOA ibuprofen12megalablastic anemiaactually it was ho a patient who was onchemo agent so they were asking abt which vit defciency coz soichoose megalablastic anemia13 ho alcholic Rx B114alziemer pat describing abt wasting it was long historythouans kwashoirkor1514 yr old kid dose nt want a read but he is good in sciencegeography play games he was active drug screen negativebut he justdont want a readthere r chosie but i choose normal coz teenagersthey dont want areadand other choicees dosent match withhistory either16 effernt arteriol constrictedso i choose FF inc GFR inc but renalplasma filo decreease u can chk in FA the same thing is thr17there is ho of grandfather thr her grand daughter she was givingall the history sho din let granda to ans doc qs so wat ur response ichoosetell lady to go out so doc can directly ask qs to the patient18 hypertensive patienton salt restrictionhe came for follwuphe said doc i don like taste of my foodwat ur responsethr rcpl of reponse but i choose give him pocket guide of salt restictionmenu19 ho immigrant kid KOREA ncant speek englishtranslatorhiredthr r some ho coin lesions on the bak of kidwat urresponsei chooseask transalator to ask mother abt coin practicethe qs abt folk medicine20 ho ASD(IN HISTORY fixe split s2)21ho photosenstivityside effectdoxycyclin22 thr is a historypat was on methotrexateprednisonethey wrasking abt wat shld we need to ad more i choose cox 2 inhibitorcoz prdnisone increaase expression of cox 2 so patient can haveinflammatory side effects thats the reason i choose cox 2 i dont knowits right ans or not23ho nulligravidarisk ofans endometrial CA24in clinical study if u find a pt with MI wat u will find in ECGichoose st segment depreesioni look for st segment elevation but i dinfind so i end with this ans25ho married couple they were tring to have baby since 2monthsther sexual practise normalthey both have orgasm normal butthey fight abt the baby prob so coz of it women is depress but at workshe is normala sexaul arousal probb dysthymia c some sexualprob i don remmebrbut i choose dysthymia i don no its ryt or rong26cohort26methoterexate27ho plantar fascitis pt was casher tenderness sole of foot fromheel to front28ho long trem pain probhad gone thru lots of dignostic measures

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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ReRemembered questions for STEP 11119522

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Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

but stil have same probcame to doc saying i thing u r foolingmewat ur responsea u can switch other docb i will refer topscycghc i am doing alll appropriate measures in order this one ichoose 292 qs abt acid base30 patient was on high alltitudenow at sea level wat will bePO2PCO2and PH31INSULIN qsho post prandial it was in grapl32secretin in graph33pt have prob in swallowing had surgerythoracicmass inmediastinum removedwat will intact after surgeryaloweresophageal sphincter responsesome more choices i don remmeber34a pt hit by a truckrearadirect injuryd hyperextensioninjuryc hypoextension i choose direct 358 yr bouy had accident sitting frontgot multiple fracturenohope of survivalwat ur respone to parentsa it must be moral 4 uguysthr some more but stupid ansi choose the one which has assurance idont remmber the choice 3677 yr old lady was on dialysis since 10 yrs she was tired of it wantno more but she was asking that am i have painful death wat urresponseu will have some fluid retention but we r here we ldo our best possible to alleviate ur problem37chlamadia38oxidase pospsedomonas39latral pontine syndrome40clozapine toxi41occulomotor 2 qs42hemisection cord 2 qs43UMN lesion44upper quadrantopniamiddle cerebral artery45picIarrow was on choroidal artery46cerebral artery47antihistamine 2 qs48teenager boy who was normalplay with friends oftenbut nowmother complaing that he sleeps althe timenot playing with palsno druabuse wat RX a chlodiazepoxide b flostinec resperidone49 ANS MEDUIM CHAIN (MCAD)NO KETONE BODIES50 urine methylmalonic acid51tb patient orange yellow urinesweateyesans rifampin52qs 19 yr old houseurine inc ALA 51cholyStyramin MOA52LDL receptor easy history5346 yr old male crying that i will die early like my fatherwat urresponsei choose tell me abt ur father how he died54dabetic pt not taking carefollow up vist wat ur responseiichoose tell me wat u know abt dibetes55another diabetic patient taking good care of diabetesexersicedailywat ur advise in endapres vit Eb fish oilc check ur feet every day56kidney stone pat wat advice u will give57obese diabetic pt wattreatmentainsulinbglyburidecmetformin58obese pt gall stoneu find in ultrasoundwat wiill be nextmangementauricodxycolic acidbopen stomech remove stonecendoscopic removal59chrons Rxsalfasalzine60chemo pt nausea vomitingrx ondansatren61moa thiazoide62in er pt have mi wat tx nitrogylycerine b beta blocker c dgixin63broad ligament of uterus64alcholicacut pancreatitis65marfan ptcystic medil necrosis66substance abuseall nihgt dancingans majuana67xray fracture arrow on navicular bone(which i did rong i m upset iknew tat but still picked wrong)68xraysholderarrow on biceps brachi69wiskot aldrich70LB471side effect of EFAVERINZE(rash history)72bcl2folicular lymphoma73blast crisiscml74obese pt sleep apneadignosisshow75ca mechanism ON SR

Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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Remembered questions for STEP 1 - USMLE Forum

httpwwwusmleforumcomfilesforum20071193828php[1172011 21026 PM]

76colon CA MISMATCH REPAIR77membranous glomerulonephritis78pt ANA positive ig GC3 DEPOSITgood patureacute gn79women 4 wt losswhich drugamphatemine80ADH SOME GRAPH ON IT81sarcodosisnoncaseating granuloma82primaquin moa83MIF (MULLERIN INHIBITORY FACTOR)MUTATION84qs abt renin graph85no spleenrisk strep pnemon8677 yr pt which vaccinei choose hinfulenza vaccineamppnemo vaccine

87seminoma88staph strepow diff ans catalase89p value was less then 1arejection of true null hypothesisbtejection of false null hypothesis90tuberssclerosis91compititive inhibitor graph92ho paranoid93plasmid bacteriaantibiotic resistance94dorsal plantar arch95cor pulmoS396benzoMOA97polyuria which druglithium98pt feeding milkdry vaginayaprolactinmore choice i donrember99rx vit k in warfarin tox100factor 2 defwhr probliverheartlungbreast101GnRHRX IN102estrogeningraph103sildenafil side effect104allupurinol moa105cycloserine moa105copd pt in graph106asking to calculate stroke volume107fibrocystic changewith cycle1083 qs on lober pnmo109acute pancreatitiscozgall stone110ketone bodiesbeta hydroxybutyrate111slide of bone formation112ribosomal rna synthesis113osteogenesis imperfectaprocollagen prob114qs abt st jhon wart medication115asprin toxirx116interferon moa117calculate meanin graph describing kids having uti118thr was control grp versus disease in grph which one have 5 yrmore survival then control119elongation step in tranlation120moa ondinavir121HTLV1122injury at L5123HARDY WEIN BRG11000SOME THIN LIKE TAT124WERD PIC ASKING ABT WHR BACTERIA IS INFECTING125CALCULATE TOATL BODY WATER126XRAYKNIFENEAR RT VENTRICAL OF HEART127HOMEO BOX MUTATIONINSTEAD HEAD LEG SOME WEIRDTHING128ALLOTYPE DIAGRAM129INH TOX

acirceurocent infant in carseat------- face to rearodd ratiowiskott -aldrishMOA of Antidote in phophate intoxication

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ReRemembered questions for STEP 11119522

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