Regenerativna medicina- priložnost za podjetja? Miomir Knežević Nacionalni inštitut za biologijo...

Regenerativna medicina-priložnost za podjetja?

Miomir KneževićNacionalni inštitut za biologijo

[email protected]

Uporabljeni material:

• Stem cells and the innovation process

– Dr Paul Martin– Institute for the Study of

Genetics, Biorisks and Society (IGBiS)

• University of Nottingham, UK

Global commercialisation of UK stem cell research

Nicola Perrin: [email protected]

Ian Bunker: [email protected]

The Role of Technology Foresight in Anticipating Global Technology Trend, Terutaka KUWAHARA, NISTEP

mailto:[email protected]









Ocene poslovnih priložnosti

Embrionalne matične celice

Tkivno inženirstvo

Ne moreš graditi ugleda na tistem, kar šele nameravaš narediti

Henry Ford

Uporaba nanotehnologije

0

5

10

15

2005 2010 2015 2020 2025 2030

Time of technological realization

Gap

(ye

ars)

Information/communications

Electronics

Life science

Health/medicine/welfare

Agriculture, etc,

Frontier

Energy/resources

Environment

Nanotechnology/materials

Manufacturing

Industrial infrastructure

Social infrastructure

Social technology

* Nuclear fusion energy area isexcluded.

Innovative nuclear power systems

New informationandcommunicationsprinciples

Basictechnology forrobotic andmanned spaceactivity

Regenerative medical science

NEMStechnology

Environmental and ecological biology

Clean-use technologyfor fossil resources

Nano devices and sensors

Zakasnitveni čas od tehnološke realizacije do uporabe

2005- 2015 2015-2025

2015年までに積極的に進めるべき融合・連携関係

2016-2025年までに積極的に進めるべき融合・連携関係

（注1）各分野で融合・連携を進めるべき当該分野以外の分野を３つまで回答。（注2）各分野で融合・連携を進めるべきと３割以上が回答した分野に向けて→を表示し、双方が該当する場合は← →で表示。（注3）赤太線は５割以上が、融合・連携が必要であると回答した領域間である。

情報・通信

ライフサイエンス

エレクトロニクス

フロンティア

エネルギー資源

保健・医療・福祉農林水産・食品

環境

ナノテク材料

製造

産業基盤

社会基盤

社会技術

情報・通信



フロンティア

エネルギー資源保健・医療・福祉

農林水産・食品

ナノテク材料

製造

産業基盤

社会基盤

社会技術

環境

2015年までに積極的に進めるべき融合・連携関係

2016-2025年までに積極的に進めるべき融合・連携関係

（注1）各分野で融合・連携を進めるべき当該分野以外の分野を３つまで回答。（注2）各分野で融合・連携を進めるべきと３割以上が回答した分野に向けて→を表示し、双方が該当する場合は← →で表示。（注3）赤太線は５割以上が、融合・連携が必要であると回答した領域間である。

情報・通信



フロンティア

エネルギー資源

保健・医療・福祉農林水産・食品

環境

ナノテク材料

製造

産業基盤

社会基盤

社会技術

情報・通信



フロンティア

エネルギー資源保健・医療・福祉

農林水産・食品

ナノテク材料

製造

産業基盤

社会基盤

社会技術

環境

Information and communications

Electronics

Life sciencesLife sciences

Information and communications

Electronics

Space, marine and earth science Space, marine

and earth science

Environment

Environment

Energy and resources

Energy and resources

Manufacturing

Manufacturing

Nanotechnology and material

Agriculture, forestry, fisheries and food

Agriculture, forestry, fisheries and food





Health, medical care and welfare

Health, medical care and welfare

Science and technology for society

Science and technology for society

*1 Respondents chose at most three fields to cooperate. *2 Black arrow indicates that 30% to 50% of respondents. *3 Red arrow indicates that more than 50% of respondents.



Multidisciplinarno okolje – Vede o življenju postajajo center

Basic research in drug development


Technology for measuring biological substances


Controlling higher-order biological functions

Higher-order brain functions

Brain generation and growth

Bioinfomatics

Basic research for new medical technologies

Nanobiology

Understanding and treating brain conditions

Inde

x po

veča

nja

znan

ja

Socialno-ekonomski pomen

Po 2015

Pred 2015Sprememba vpliva “Ved o življenju”

Predvideni čas realizacije tehnologij – Vede o življenju

Čas uporabe v praksi

9.0 yrs.

9.0 yrs.

10.8 yrs.

10.6 yrs.

11.4 yrs.

10.8 yrs.

11.3 yrs.

11.0 yrs.

10.6 yrs.

2005 2010 2015 2020 2025 2030 2035

Information biology

Controlling higher-order biologicalfunctions


Technology for measuring biologicalsubstances


Nanobiology


Understanding and treating brainconditions

Basic research for new medicaltechnologies

Bioinformatics

Controlling higher-order biological functions






Nanobiology


Čas tehnološke realizacije

Najpomembnejše tehnologije na področju Ved o življenju “Top 10”

Topic Area Year

Effective technology to prevent cancer metastasis. Basic research for new medical technologies

2020 / 2030

Technology for immediate, complete control of allergies based on elucidation of the immunoregulatory mechanisms and environmental factors that lead to hay fever, atopic dermatitis, and other allergies.


2015 / 2027

Treatment for preventing the progression of Alzheimer's disease. Understanding and treating brain conditions

2019 / 2030

Elucidation of the etiology of manic-dpressive psychosis at the molecular level.


2020 / -

Technology to detect a cancerous tissue of the diameter smaller than 1 mm presenting anywhere in the body.


2014 / 2023

Elucidation of the etiology of schizophrenia at the molecular level. Understanding and treating brain conditions

2022 / -

Technologies for drug development to predict bioactivities of proteins such as interactions between protein and protein, between proteins and DNA or RNA, and between proteins and synthetic compounds from their higher order structure.


2015 / 2026

Mass production technology for fuels and bioplastics utilizing plants and microorganisms.


2014 / 2024

Technology to manipulate stem cell differentiation and growth for induction of functional cells to use for therapy.


2016 / 2029

Effective cancer prevention measures can be implemented by clarifying the relationships among multiple environmental risk factors associated with cancer.


2020 / 2030

: Nove medicinske tehnologije in zdravila: Študij možganov

: Regenerativna medicina

Regenerativna medicinaTehnološka pot

Izdelava umetnih

organov

Razvoj osnivne

tehnologije

Long-term organ cultivation and preservationtechnology for organ transplants.

Reprograming technology to create stemcells from differentiated somatic cells.

Technology to manipulate stem celldifferentiation and growth for induction offunctional cells to use for therapy.Technology to utilize animals as a bioreactorto produce organs and tissues to transplantinto humans.

Artificial retinas to give sight to the visuallyimpaired.

Artificial organs incorporating human cellsand tissue.Synthetic technology for artificial cells withfunctions such as cell membrane transport,material transfer, and energy conversion.

2025 2030 20352005 2010 2015 2020

Time (years)

Value

5 10 15 20

Training

Cell therapies

Research tools Clinical trials

Manufacturing

Drug screening

Cell banking

Growth factors

Toxicity testing

Therapeutics

Research applications

Enabling technologies

Timescale for commercial opportunities

Stopnje:

Infrastruktura:

Deležniki:

Financiranje:

????

Basic ResearchApplied Development

Clinical Therapies

Universities, Research Institutes

Biotech SMEs Pharma

Clinicians

Government / regulatory agencies

Commercial funding VC, pharma

Research Councils Charities

Manufacturing

Funding Gap

Translation of stem cell research into commercial products

Noben uspeh ni dokončen, nobena napaka ni nepopravljiva: šteje le pogum, da nadaljuješ.

Winston Churchill

Regenerativna medicina- priložnost za podjetja? Miomir Knežević Nacionalni inštitut za biologijo...

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