regenerative products - iRES Group · regenerative products. 1 an eye for details iRES® develops,...

regenerativeproducts

1

an eyefor

details

iRES® develops, manufactures and distributes biomaterials for bone and tissue regeneration, and oral

and maxillofacial surgery. Our mission is to keep people at the heart of our work, combining meticulous attention to detail and ongoing research into safe and innovative

new products of the highest quality that offer real value in terms of quality and price.

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ShapeBone® is our new composite material, which we have developed for bone regeneration in reconstructi-ve oral, periodontal and maxillofacial surgery. ShapeBone® was developed by combining natural mineral structu-res of bovine origin with resorbable biopolymers (to provide structural strength) and polysaccharides as cell nutrients. A new concept in compo-

site material, ShapeBone® allows ra-pid growth of, and colonisation by the patient’s own cells. The biopolymers in the matrix degrade within 18 weeks, stimulating the generation of bone tissue and facilitating complete inte-gration.

The new composite bone substitutederived from bovine tissue

Elevated biocompatibility:

The processes and source materials used in the manufacture of ShapeBo-ne® produce a product with eleva-ted levels of biocompatibility. In vivo testing and clinical trials have shown it to be fully compliant with ISO10993 standards.

Open-pore microstructure:

ShapeBone® is made with natural materials and features interconnected osseous trabeculae ranging in size from 50 to 150 microns. The bone type is predominantly sponge-like with an interconnected porosity of 27%, which is effective in promoting cellular colonisation.

availablealso custom

SWISS MADE

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Horizontal and vertical augmenta-tion of atrophied alveolar ridge | Re-pair and filling of alveolar defects to preserve the alveolar ridge following tooth extraction | Repair and filling of extraction defects to create an implant site | Repair and filling of in-traosseous pockets with two or more walls and bi- and trifurcation defects | Membrane support for guided tis-sue regeneration (GTR) | Defects fol-lowing tooth removal surgery or cor-rective osteotomy | Defects following removal of osseous cysts | Maxillofa-cial reconstruction | Augmentation of the maxillary sinus floor | Peri-implant defects.

Limited resorption:Limited initial resorption (less than 5%) thanks to the polymer membrane (coating), which performs a triple fun-ction, specifically:• facilitating cellular colonisation, by virtue of its elevated hydrophilicity;• strengthening the matrix, imparting increased resistance to mechanical compression during surgical wound closure;• providing a protective barrier against inflammatory attack.

Elevated dimensional and volumetric stability:The limited initial resorption has the immediate benefit of allowing the use of less material than normal protocols,

in which an additional 35-40% extra material is added to compensate for the initial loss of volume. This impro-ved performance is also advantage-ous for the management of soft tis-sues, insofar as the soft tissue needs trimmed back to a lesser extent and, as such, need not be stretched so far, making suturing more straightforward.

Additional information:• Certified Class III medical device, compliant with ISO 10993 standards and the Medical Device Directive 93/42 EEC.• Can be stored at a temperature of +2°C to +25°C for up to 4 years• Radiopaque• Osteoconductive

Featuresand benefits

Elevated hydrophilicity:

ShapeBone® is highly hydrophilic. Its micro-composition, which includes the presence of polysaccharides, is designed to increase permeability and hydrophilicity, characteristics that assist bone remodelling and vascula-risation. Newly implanted ShapeBo-ne® will rapidly absorb 38% its own weight in blood.

Outstanding mechanical performance:

ShapeBone® undergoes a unique treatment that imparts elevated ela-sticity and load resistance. Shape-Bone® can withstand high levels of compression (up to 350kg/cm2), can be drilled and cut, and can accom-modate all fixation systems. It can withstand 3 times the maximum com-pression level of its main competitors, with up to 4 times the level of rigidity.

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shapebone

il miglior competitor

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25

20

15

10

50 2- 5- 7- 9- 11- 13- 16- 18- 21- 23- 25- 27- 30- 32- 34- 37- 39- 41- 43- 46- 48-50

MPa

(str

ess)

% di compressione

Elevated mechanical performance ShapeBone® exhibits rigid pseu-doelastic behaviour. It can withstand a maximum load three times greater than that of its competitors, and is four times as rigid.

Uniaxialcompression test

Histology and density

Vigorous growth of new bone tissue following a ShapeBone graft (black arrow) is indicated by the presence of osteocytes in the lacunae (yellow arrow). Mature lamellar bone formation and osteoblasts producing neo-formation bone tissue in surrounding areas that contain bone neo-tissue can also be identified (green arrows).

The ShapeBone graft (black arrows) is progressively replaced by immature, neo-formed bone tissue (green arrows). Osteoblasts can be observed both in their active state and at rest, at which point, having formed the mature bone (yellow arrows), they become oste-ocytes.

*All histological and densiometric testing was conducted on human subjects, four months after the application of the graft.

The progressive expansion of tissues during the osseointegration of the ShapeBone graft (black arrows) mirrors its evolution over time: the diffusion of osteoblast colonies (grey ar-rows) is indicative of a gradual substitution of the graft by immature, neo-formed bone and the subsequent transformation into mature lamellar bone (yellow arrows).

The CT scan confirms the elevated degree to which ShapeBone integrates with the body’s own tissues, revealing the lack of demarcation between the implant and the native bone, the latter displaying normal morphometric structure. The average neo-formed bone density (sampled at the ShapeBone graft surrounding the mini-screw mount) is 500 HU.

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Code Desc. Dim. (mm) Q.ty Price

SB005 Microchips 0.25-1 0.5 cc 69,00 €

SB010 Microchips 0.25-1 1 cc 81,00 €

SB020 Microchips 0.25-1 2 cc 129,00 €

SB050 Microchips 0.25-1 5 cc 279,00 €

SB121 Microchips 1-2 1 cc 84,00 €



SB250 Granules 2-4 5 cc 194,00 €

SB011005 Block 7x7x7 1 209,00 €

SB011010 Block 10x10x10 1 230,00 €

SB011020 Block 10x10x20 1 345,00 €

SB011030 Block 10x20x20 1 550,00 €

SB011110 Block 14x12x6 1 270,00 €

SB011130 Block 14x12x8 1 290,00 €

SB011160 Block 14x12x12 1 370,00 €

SB011180 Block 14x12x20 1 490,00 €

SB011190 Block 14x12x24 1 560,00 €

SB011210 Block 15x30x20 1 780,00 €

SB011220 Block 15x30x30 1 830,00 €

Descriptions,codes,prices

Code Desc. Dim. (mm) Q.ty Price

SB011230 Block 15x30x40 1 960,00 €

SB011250 Block 15x30x60 1 1.500,00 €

SB011310 Block 16x14x6 1 350,00 €

SB011330 Block 16x14x8 1 390,00 €

SB013040 Plate 10x10x4 1 200,00 €

SB013010 Plate 3x25x15 1 290,00 €

SB014010 Wedge 35x22x5 1 527,00 €

SB014030 Wedge 35x25x10 1 800,00 €

SB014060 Wedge 40x25x14 1 1.120,00 €

SB012010 Cylinder Ø11x20 1 590,00 €

SB012030 Cylinder Ø14x20 1 690,00 €

SB012050 Cylinder Ø11x10 1 430,00 €

SB012060 Cylinder Ø14x14 1 590,00 €

SB016010 Shape U 15x6x4 1 345,00 €

SB016020 Shape U 15x7x3.5 1 345,00 €

SB016210 Shape L 15x7x6 1 345,00 €

SB016110 Shape C Ø8x12 1 345,00 €

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01) FixLite® stimulates an antimicrobial reaction by combining two products, a diode laser and a photoactive so-lution.

02) FixLite® was developed for the detoxification and biostimulation of gingival and osseous tissues.

03) FixLite® is designed to be sim-ple enough for everyday use in the treatment of mucositis, gingivitis, pe-ri-implantitis, periodontitis and ab-scesses, for improving the safety of the post-extraction implant process, for managing secondary intention surgical wound closure, for cleaning the alveoli, for assisting the regenera-tion of both hard and soft tissues, and for managing surgical complications

caused by bacterial inflammation.

04) FixLite® has been designed to be ready to use immediately upon supply and is intended for decontamination, regeneration, peri-implantitis, and medium and light biostimulation.

05) The FixLite® system can be pre-set for specific functions thanks to the programmes and rigid protocols loaded into the system. Furthermore, it is effective on all tissue types and implant surfaces.

06) FixLite® is also supplied ready for use in soft-tissue surgery, endodon-tics, whitening and various other tre-atments.

An innovative system that combines diode lasers (hllt) and a photoactive solution

What’s in the box?• Compact laser unit 14 cm (l) x 15 cm (h) x 24cm (d)• Laser transmission fibre integrated with handpiece• Control pedal• 3 pairs of safety glasses• External mains power adaptor• 1 USB cable• 1 tip bender• 1 pack of 4 x 400-micron interchan-geable single-use tips• 1 user’s manual

Features:• Compact laser unit 14 cm (l) x 15 cm (h) x 24cm (d) with 4.3 “color chart” screen• Interchangeable tips• Multi-tip handpiece• USB port

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Code Price

FixLite Completo 8.500,00 €

FixLite Solutions 120,00 €

FixLite Tips 50,00 €

Descriptions, codes, prices

• Customised software featuring five preset clinical programmes for trea-ting: 1. Peri-implantitis 2. Regenera-tion 3. Periodontal decontamination 4. Light biostimulation 5. Medium biosti-mulation

The solution:FixLite® biostimulation solution has been PATENTED. An innovative solu-tion with anti-microbial and biostimu-lation properties. FixLite®’s precise patented formula is an industrial se-cret.

Solution packages:The solution is supplied in 4 strips, each containing 5 single-use 1.5-ml phials. On average, one strip is suffi-cient for complete treatment of one patient.

The patented FixLite® technique:01) An example of PHOTODYNAMIC THERAPY, which is to say the deacti-vation of cells, microorganisms or molecules using HIGH INTENSITY li-ght (HLLT – High Level Laser Therapy), rather than heat, employing a DIODE laser to achieve deep penetration of tissues.02) Using this laser in combination with the patented solution enables: 2a) maximal penetration; the wavelen-gths used can penetrate up to 2 cm into gingival and osseous tissues. 2b) the avoidance of thermal effects, due to a low average power. 2c) effecti-ve ANTIMICROBIAL action and BIO-STIMULATION of tissues thanks to the properties of the patented solution. 2d) the production of singlet oxygen thanks to the use of high frequencies.

03) It is a well-documented technique that has been used in the dental sec-tor for more than 15 years.04) For the treatment of PERI-IM-PLANTITIS, PERIODONTITIS, BONE REGENERATION and ENHANCED BIOSTIMULATION of tissue.

Benefits of FixLite®:01) The DIODE laser stimulates detoxi-fication, microbe elimination and bio-stimulation processes, even at depth.02) HLLT therapy guarantees eleva-ted levels of tissue decontamination compared to the superficial effects of the LLLT (Low Level Laser Therapy) currently on the market.03) FixLite® solution is highly effective for three reasons: 3a) it is transparent, and does not impede the effects of the laser. 3b) it produces antimicrobial effects and detoxifies without the use of a colouring agent. 3c) it penetrates deeply, achieving enhanced levels of detoxification.04) The system is safe and follows preset protocols based on 15 years of documented use.05) Free, specialised training for me-dical practitioners.

For the treatment and cure of:Peri-implantitis | Periodontitis | Muco-sitis | Abscesses | Gingivitis. Also for use in: detoxification prior to surgery; anti-microbial protection following cyst removal; biostimulation of tissues to promote regeneration.

Comparisons with our competitors:01) FixLite® uses photodynamic HLLT (High Level Laser Therapy). Other commercially available lasers employ photodynamic LLLT (Low Level Light Therapy).02) FixLite® uses a diode laser in combination with a patented solution that acts on bacteria within the tissue, whether a colouring agent has been used or not. Other commercially avai-lable laser systems require the use of colouring agents. These (our main competitors) have been shown to be relatively ineffective because they eliminate only those bacteria that are coloured by the solution, and/or tho-se struck directly by the laser, meaning they are effective only on superficial layers and not deep within the tissue.03) The efficacy of the FixLite® is not compromised by the presence of air pockets during treatment.04) Treatment is faster than the long processes involved in applying com-peting treatment products.

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A synthetic bone grafting material marketed worldwide, CERASORB® consists of phase-pure (>99%) granular ß-tricalcium phosphate for fi lling bone defects in oral and maxillofacial surgery. The granular products are characterized by their interconnecting porosity and their osteoconductive properties. CERASORB® comes in different presentations with distinct granule sizes, porosities, resorption rates and handling characteristics to serve different needs. The product

is characterized by a high level of handiness.

• Well documented in more than 135 scientific publications

• World Reference Standard for all materials of its class

• Successfully used worldwide in clinical practice for more than twelve years

• More than one million units sold in 75 countries worldwide

The reliable choice for regenerating bone

CERASORB® β-TCPCERASORB® ClassicCERASORB® MCERASORB® PerioCERASORB® Plus

COMPLETELY REABSORBED

MATERIALDURING BONE

REGENERATION. LEAVES NO RESIDUE

AND IS REPLACED WITH NATURAL

BONE.

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SafetyCerasorb® is composed of calcium and phosphate, both bone elements. It’s well tolerated by the body without immune-mediated risks or risks of infection that may be observed with materials of biological origin. It does not produce systemic and local toxicity and it is non-allergenic. Because of its homogenous solubility, it releases calcium and phosphate ions in the site in physiological concentrations (Ca/P ratio 1:5). These are easily absorbed by osteoblasts for bone mineralization. It is then reabsorbed within the formation of the new bone.

ProductionCerasorb® is produced in a clean room, through a sterilization process, through a high temperature process, validated and controlled

by computer. Its basic components are calcium carbonate and calcium hydrogen phosphate. The material is then ground into granules of defined sizes, and then sieved into the final product (Cerasorb® Classic, Cerasorb® Perio e Cerasorb® M). While Cerasorb® Classic is finally shaped as a “snowball”, other products are processed to reach a lenghtened shape after a cold isostatic compression of 150-200 MPa. For Cerasorb® M an Additive is added to obtain the desired porosity. The polygonal granules are produced with a special grinding technique and then sieved to obtain granules of different sizes.

QualityThe quality of the starting synthetic components and materials for packaging is controlled for

admittance The synthesis of Cerasorb® is controlled by many chemical and mineralogical tests performed internally and externally. The product complies with international standards, i.e. ASTMF-1088-04 (Specific Standard forl ß-tricalcium phosphate for surgical implant). Its pure phase (99%) exceeds 99% of purity required by the Standard. The product is packaged in a clean room and then exposed to validated gamma rays, sterilized by gamma rays and delivered in packs in rigid double blisters. The color coded cover helps to select the more convenient size of the granules. The covers are easy to open by unscrewing them.

CERASORB® ClassicWith its open interconnecting microporosity (about 35%) its stable microstructure facilitates the entry of body fl uids and the ingrowth of blood vessels and cellular elements and prevents mi-croparticulate break-down and resultant undesired phagocytosis.

Granule size:150–500 μm, 500–1.000 μm, 1.000–2.000 μm

CERASORB® MIs characterized by an open interconnecting multiporosity with micro, meso, and macropores (5 µm – 500 µm) and a total porosity of about 65 vol. %. Its polygonal, irregularly shaped granules facilitate wedging and interdigitation at the site. Micromotions are largely prevented.

Granule size:500–1.000 μm, 1.000–2.000 μm

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CERASORB® PerioSpecifically developed for the management of periodontal bone defects, CERASORB ® Perio consists of polygonal granules. Its porosity is 20 + 5 vol.%. This facilitates wedging and interdigita-tion of the polygonal granules, which form a stable agglomeration with an optimal resorption rate.

Granule size:63–250 μm, 250–500 μm

CERASORB® PlusPredictable resorptionCancellous bone will resorb faster than new bone that is formed. CERASORB®Plus acts as a resorption reducing agent. Cortical bone and non-resorbable bone grafting materials usually persist in the defect for years and undergo very slow resorption. CERASORB® Plus provides the space needed by autogenous bone.

Dimensione dei granuli:500 – 1.000 μm

Indications for use:

Indications for use: before applying Cerasorb®, mix with autologous blood. Fill the defect entirely, introducing the material in direct

contact with the bone. Avoid excessive condensation and breaking up of the granules.

INDICATION CERASORB® PRODUCTS GRANULE SIZE

Periodontal defects Cerasorb® Perio 63-250 µm | 250-500 µm

Apicoectomies Cerasorb® Classic & Cerasorb® M 500-1.000 µm

Post-extraction alveoli Cerasorb® Classic & Cerasorb® M 500-1.000 µm

Cystectomies Cerasorb® Classic & Cerasorb® M 500-1.000 µm | 1.000-2.000 µm

Augmentation of the maxillary sinus floor

Cerasorb® Classic 500-1.000 µm | 1.000-2.000 µm

Cerasorb® M 500-1.000 µm | 1.000-2.000 µm

Filling in peri-implant spaces Cerasorb® Classic & Cerasorb® M ggf 500-1.000 µm

Most commonly used varietiesCerasorb® Classic 500-1.000 µm

Cerasorb® M 500-1.000 µm | 1.000-2.000 µm

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Code Granule size Quantity Price

6000054-A 1.000-2.000 µ 1 x 1 cc 90,00 €

6000054 1.000-2.000 µ 5 x 1 cc 367,00 €

6000063-A 500-1.000 µ 1 x 2 cc 170,00 €

6000063 500-1.000 µ 5 x 2 cc 679,00 €

6000064-A 1.000-2.000 µ 1 x 2 cc 170,00 €

6000064 1.000-2.000 µ 5 x 2 cc 679,00 €


6000043-A 500-1.000 µ 1 x 0,5 cc 50,00 €

6000043 500-1.000 µ 5 x 0,5 cc 198,00 €

6000044-A 1.000-2.000 µ 1 x 0,5 cc 50,00 €

6000044 1.000-2.000 µ 5 x 0,5 cc 198,00 €

6000053-A 500-1.000 µ 1 x 1 cc 90,00 €

6000053 500-1.000 µ 5 x 1 cc 367,00 €

CERASORB® Classic


6000001 A 500-1.000 µ 1 x 0,5 cc 50,00 €

6000001 500-1.000 µ 5 x 0,5 cc 198,00 €

6000002 A 1.000-2.000 µ 1 x 0,5 cc 50,00 €

6000002 1.000-2.000 µ 5 x 0,5 cc 198,00 €

6000011 A 500-1.000 µ 1 x 1 cc 90,00 €

6000011 500-1.000 µ 5 x 1 cc 367,00 €


6000012 A 1.000-2.000 µ 1 x 1 cc 90,00 €

6000012 1.000-2.000 µ 5 x 1 cc 367,00 €

6000021 A 500-1.000 µ 1 x 2 cc 170,00 €

6000021 500-1.000 µ 5 x 2 cc 679,00 €

6000022 A 1.000-2.000 µ 1 x 2 cc 170,00 €

6000022 1.000-2.000 µ 5 x 2 cc 679,00 €

CERASORB® M


6000081-A 63-250 µ 1 x 0,5 cc 65,00 €

6000081 63-250 µ 5 x 0,5 cc 261,00 €


6000082-A 250-500 µ 1 x 0,5 cc 70,00 €

6000082 250-500 µ 5 x 0,5 cc 261,00 €

CERASORB® Perio


6000073 500-1.000 µ 5 x 1 cc 418,00 €

6000075-A 500-1.000 µ 1 x 2 cc 165,00 €

6000075 500-1.000 µ 5 x 2 cc 749,00 €


6000071-A 500-1.000 µ 1 x 0,5 cc 60,00 €

6000071 500-1.000 µ 5 x 0,5 cc 239,00 €

6000073-A 500-1.000 µ 1 x 1 cc 105,00 €

CERASORB® Plus


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The formulation of CERASORB® Paste is based on the latest developments in our understanding of bone biology. The proven properties and benefits of CERASORB® synthetic granules are now available suspended in a hyaluro-nic acid matrix that is effective in pro-moting healing.

Syringe supplied ready to use: ma-terial for bone regeneration in paste form, supplied in a pre-filled syringe for immediate application.

Optimised over 15 years of clinical use, CERASORB® M granules, which fea-

ture an interconnecting pore system, provide an effective guide for the formation of the new bone structure. Produced synthetically, they avoids the potential risks inherent to material derived from human or animal donors, such as immunological reaction or in-fection. The granules are resorbed as the new bone is formed.

All studies conducted on CERA-SORB® paste have shown it to be highly biocompatible. Both the par-ticles of ß-TCP and the support me-dium are completely resorbed as the new bone tissue is resorbed.

Resorbablepaste forfilling in and reconstructingosseousdefects withone or morewalls

CERASORB® PASTEß-tricalcium phosphate paste

The formulation of the paste means it retains a

ductile, volumetrically stable form even inside the defect, up to the point that

it is completely resorbed.

The hydrogel support does

not harden either during or

after application

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Quick andeasy to apply

Complete bone regeneration

The CERASORB granules and hyaluronic acid are complete resorbed by the body and the bone is restored to its healthy state. The CERASORB granules and hyaluronic acid medium are broken down completely and replaced by the patient’s own bone cells. New research indicates that the hyaluronic acid actually promotes the differentiation of stem cells into osteoblasts and has an anti-inflammatory effect. Two studies conducted on rabbit subjects studied CERASORB Paste in detail. In both studies, bone structure had been entirely restored after just 6 months. Defects filled with

The density of the paste is about 2 g / cm3

CERASORB Paste healed completely, while untreated defects were found still to be largely unfilled after 6 months. In another study, CERASORB Paste was used

in scapula defects in sheep. Bone regeneration within the defect was identifiable after just 6 months, and after 12 months the spongiosa had been completely restored to its original healthy condition. After 6 months, the defect has regenerated with osseous tissue, and the process

of bone remodelling, which will lead to restoration of the original bone structure, is well under way. In the newly formed bone, traces of ß-tricalcium phosphate can be detected in a state of advanced degradation. In other words, they are surrounded by the newly formed bone tissue with excellent levels of bone contact. After 12 months, the defect has regenerated with osseous tissue, and the original bone structure has been fully restored with both compact and spongy bone. The ß-TCP has been completely resorbed.

The paste is applied directly to the defect using the syringe.

Mixing with blood or other fluids is not required.

CERASORB Paste can be applied with precision directly from the ready-fil-led sterile syringe, allowing effective application to even the most diffi-cult-to-access sites. Once the defect is fully filled, the paste offers optimi-sed and extensive surface contact with the surrounding healthy bone.

Method 1To use the syringe for direct application simply remove of the cap, which functions as a Luer Lock adaptor.

Method 2Syringe with Luer Lock adap-tor in place for application via cannula to sites that are diffi-cult to access.

Code Contents Price

9001304041 0,5 cc 107,00 €

9001304051 1 cc 190,00 €


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CERASORB® FOAMFoam of β-TCP

CERASORB® Foam can be used in dentistry and maxillofacial surgery with the following indications: refilling or reconstruction of non-infected bone defects with one or more walls, such as:• Filling alveolar defects to preserve the alveolar ridge following tooth ex-traction

• Augmentation of an atrophied alve-olar ridge• Filling post-extraction defects to prepare the site for an implant

Carefully remove all bone residue and necrotic tissue before introducing the bone regeneration material. Be-fore the material is inserted, it is vital

that the CERASORB® Foam be able to come into direct contact with the living, bleeding bone and that the bone be carefully cooled. Impregna-te the CERASORB® Foam with blood from the area of the defect or with sa-line solution prior to the insertion.

Alveolus filling material with a double benefit volumetric stability and effective support during bone regeneration

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CERASORB® Foam materials for bone regeneration are resorbable, osteo-conductive and have similar proper-ties to the spongiosa. They are for-med from a composite of ß-tricalcium phosphate and porcine collagen and are indicated for the filling and joining of bone defects resulting from dege-nerative conditions or trauma.

Formulation

The matrix structure of CERASORB® Foam promotes regeneration of bone tissue in three dimensions. When the synthetic, bioactive ceramic mate-rial comes into contact with the living bone, it is resorbed by the body over a period of months during which time it is replaced by the patient’s own lo-cal bone tissue. CERASORB® Foam is radiopaque.

PropertiesCERASORB® Foam, the perfect size for filling alveolar defects.

Once impregnated with blood, the material can be moulded to fit the precise form and size of the defect.

CERASORB® Foam is easy to position

Insert the material without exerting pressure, leaving it uncompressed.

CERASORB® Foam is easy to work and mould to the shape and size of the defect. Positioning is equally straightforward. To this point, it has produced no unwanted side effects or interacted with medication or other medical devices. CERASORB® Gra-nulate has been used clinically, with positive results, for over 15 years and is documented in over 150 scientific publications. Combined with colla-gen in CERASORB® Foam, it produ-ces a dual benefit: volumetric stability and effective support during bone regeneration.

Productsafety


Code Contents Price

8001001010 0,5 cc 146,25 €

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The optimized hydroxyapatitehigh porosity synthetic ha

HA 95% • β-TCP 5%

Osbone® Dental is a new-generation, synthetic hydroxyapatite offering a sate and effective alternative to hydroxyapatite products ot human or animai origin. lts high porosity and ability tor rapid osseointe gration makes it an excellent choice for:• Socket preservation• Highly stable implant beds• Sinus lifting procedures

• Ridge augmentations• Guided Tissue Regeneration• Buccal wall detectsThe use ot Osbone® Dental may prove to be the best solution despite the presence ot challenging situations such as nicotine abuse, metabolic diseases, osteoporosis and other cases where bone growth is compromised.

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9000800505 250-1.000 µ 5 x 0,5 cc 199,00 €

9000801005 250-1.000 µ 5 x 1 cc 330,00 €

9000902001 1.000-2.000 µ 1 x 2 cc 130,00 €

Osbone® biocompatibility

Osbone® demonstrates excellent cell proliteration. In contrast, bovine hydroxyapatite only produced isola-ted cells and a low proliteration atter 28 days.

Interconnecting spongious open-cell pore structure

The high porosity of Osbone® (80%) provides an optimized open-cell structure that closely resembles hu-man cancellous bone.

Additional Osbone® advantages

High patient acceptance - Osbone® is readily accepted by patients thanks to the fully synthetic origin. Patient in-formation need not address possible complications and risks of immunolo-gica! reactions or infections of biolo-gica! origin. No complicated record keeping necessary - Simple patient labels are included with Osbone®, but there is no requirement tor ex-tensive record keeping and reporting as with human materiai. Natural osse-oinductivity - Osbone® is mixed with the patient’s own blood to provide enhanced healing and form a put-ty like consistency, allowing the pa-tient’s own cells to stimulate growth. No hazardous waste - In contrast to materials of biologica! origin, the pro-duction process Osbone is ecologi-cally friendly and does not produce any hazardous waste.

Ideal flexibility for immediate or delayed placement

An open study with 32 centers, 190 patients, and at least 12 months fol-low-up has been published using Osbone2 Of the augmented implant areas, 98.7% were reported as suitable at the time of implant placement. Im-mediate placement was performed in 117 of the implants. The authors repor-ted that there was “... never any loss of a dental implant, confirming the sta-bility of the healed ceramic materiai.”


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Membrane to be used for applications: GBR (Guided Bone Regeneration) GTR (Guided Tissue Regeneration)

Unique resorbable collagen membranetranslucent,resilient,flexible

CollaGuide® is manufactured from Type 12i bovine collagen with no che-mical cross-linking creating an excel-lent healing environment. lt is free of any additional chemicals. These pro-perties promote healing and con-sistent resorption. (Wang H. Carroll W. Guided bone regeneration using bone grafts and collagen membra-nes. Quintessence lnternational. 32, 2001; 504-515.)

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Code Dimensions Quantity Price

6000141 15 x 20 mm 1 107,00 €

6000142 20 x 30 mm 1 120,00 €

6000143 30 x 40 mm 1 186,00 €

Collaguide® it’s available in three different size:Collaguide® 15 x 20 mmCollaguide® 20 x 30 mmCollaguide® 30 x 40 mm

Descriptions, code, prices

TranslucentEasy to piace! For the first time any bone graft is visible. Ability to check at any time.

Resilient and flexibleEasy to handle! When hydrated, the membrane is easy to handle, can be cut to size, flexible and easy to piace. lf needed, CollaGuide® can be fixed with sutures or tacks.

ResorbableSecond surgery unnecessary to remo-ve membrane. As the barrier resorbs, a matrix is created that allows fibroblast infiltration and cellular attachment.

Collaguide® membrane can be ap-plied with any bone substitute material or bone formation on the market. It is recommended to use the bone for-mation material Cerasorb®.

Dimensions disponibili:15x20 mm | 20x30 mm | 30x40mm

lts dense fibrous structure crea-tes a porosity designed to retard epithelial downgrowth and prevent gingiva connective celi migration into the wound site.

As the barrier resorbs, fibrils that make up the membrane separate, creating a matrix that allows fibroblast infiltration and cellular at tachment.

Collaguide® membrane cropped

Before closing. You can see the graft through the membrane

Two weeks after surgery

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9000701520 15x20 mm 1 115,00 €

9000702530 25x30 mm 1 140,00 €

9000703040 30x40 mm 1 195,00 €

Membrane to be used for applications: GBR (Guided Bone Regeneration) GTR (Guided Tissue Regeneration)

The membrane of choice inguided tissue regeneration and guided bone regeneration


Osgide® is a bioresorbable barrier membrane for use in guided tissue regeneration (GTR) and guided bone regeneration (GBR).The resorbable Osgide® membrane is used as protec-tion for bone repla-cement material to assist bone rege-neration for periodontal bone defects and bone augmentation. Osgide® is a highly pure membrane that is manu-factured from porcine raw materials under controlled and standardised processes and consists of a fibre network of collagen and elastin.The membrane creates a protected environment for bone regeneration in the defect area, by presenting a bar-rier against the migration of soft tissue and assists the ingrowth of osteoge-nic cells in the bone defect. The fibre network of Osgide® prevents the mi-gration of bone replacement material and provides mechanical stability in the region to be reconstructed.

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Benefits of Osgide®

The Osgide® membrane has the fol-lowing benefits as a result of sophi-sticated technical manufacturing pro-cesses:• High therapeutic safety due to re-liable barrier function• Excellent biocompatibility and cell compatibility• Very good plasticity• High tensile strength• Ideal combination with different bone replace-ment materials• Simple and reliable application

Cruciala dependable barrier function!

Osgide® is a bioresorbable membra-ne so that a second surgical proce-dure to remove the membrane is not required. The stability compared with degrada-tion is of great importance for resorbable membranes. Many stu-dies show that the barrier function is often only guaranteed for a relatively short time for non-cross-linked colla-gen membranes and can vary widely.For this reason, great importance was attached to reproducible high stability during the development of Osgide® where good tissue integration and va-scularisation of the non-cross-linked membrane are preserved. Due to the slowed biodegradation of Osgide®, the barrier function of the membrane is not interrupted prematurely and is preserved for more than 12 weeks. This was shown in comparative studies with other non-cross-linked membranes.

Excellent handling

Osgide® is also safe and easy to han-dle in a wet state. It is characterised by simple and universal handling and can be cut with scissors or a scalpel to the size of the defect. Depending on the size, several small defects can be treated with one membrane. Due to the high stability, it does not bre-ak. It does not stick and ideally adapts to the tissue and bone replacement material used. As a result, you save va-luable time!

The use of membranes for bone aug-mentation

The use of barrier membranes has be-come the clinical standard for GTR and GBR procedures. To achieve a safe treatment success in bone aug-men-tation, professional societies recommend the use of barrier mem-branes in combination with bone re-pla-cement materials. Scientific studies show that more bone is formed the bone regenera-tion process and the implant survival rate increases when membranes are used. In the USA, the Food and Drug Administration (FDA) recommends that suitable membranes are to be used for bone development to pre-vent the migration of bone replace-ment materials.

What happens when osgide®is resorbed?

Osgide® is initially integrated in the surrounding tissue and resorbed by the body‘s own processes. No toxic degradation products are released during this resorption process.It does not result in the release of contaminants such as cross-linked

substances or pH value changes that are observed for synthetic polymer membranes.

Is osgide® chemically cross-linked?No, chemical cross-linking was enti-rely dispensed with Osgide®. In the literature, strong chemical cross-lin-king is associated with an increased incidence of dehiscence.

Is there a risk of confusion of the membrane sides during application?

No, Osgide® has two different si-des which can not be confused. The smooth side should be positioned towards the mucosa in order to assist soft tissue healing and to avoid migra-tion in the augmentation (GTR).The rough side facing the bone serves as a guide for the osteoblasts in the GBR and enables rapid development of the bone graft.

Does osgide® has to be rehydrated be-fore use or even washed?

No, Osgide® is very hydrophilic and wets in a few seconds. Osgide® is not cross-linked. For this reason, it does not contain potential toxic resi-dues that could result from a chemical cross-linking process.

Should osgide® only be combined with certain bone replacement ma-terials?

Osgide® can be combined with all commercially available bone replace-ment materials and autologous bone. To gain a stable implant location, the combina-tion with Osbone® bone replacement material can be recom-mended.

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LAYER 3GINGIVAL INTERFACE

The outer surface with its embossed textured

surface consists of large inter-connective pathways.

The inner structure decelerates fibroblasts infiltration and improves

cell apposition. Histological examinations have demonstrated

connec-tive tissue entering the internal matrix structure, depositing

collagen fibers.

LAYER 2INTERMEDIATE LAYER

A well-organized blood clot forms inside the labyrinthine structure

between the two different outer surfaces. This supports the

formation of collateral vessels and an unrestricted flow of interstitial fluid.

The hollow spaces, which are irregular in shape and size, form a framework

for the apposition and stabilization of fibroblasts, actively supporting the

healing process.

LAYER 1 DEFECT INTERFACE

This layer consists of closed pores and ensures that generous amounts of

blood are adsorbed, at the same time facilitating the adaptation

of the membrane to the tooth surface. This layer also serves as

a barrier, preventing the migration of fibro-blasts and apical ingrowth

of epithelial cells. By doing so, it promotes gingival attachment.

Bioresorbable barrier matrixbased acid polylactic

The unique membrane structurebio - resorbable with multiple applications: GTR (Guided Tissue Regeneration) GBR (Guided Bone Regeneration)

Three-Layer TechnologyThe patented barrier matrix is cha-rac-terized by its unique three-di-mensional architecture. This internal structure creates a three-dimensional gradient of density de-signed to al-low fibroblasts and epi-thelial cells to enter the hollow spaces and to atta-ch themselves to the walls, stabilizing these cells in the process. The inno-vative structure is easily re-cogni-zable in the cross-section: The inner layer, featuring large and closed po-res, transforms into a chamber-like structure in the intermediate layer and then into the highly porous outer layer, also featuring large pores.

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3° strato

2° strato

1° strato


6000110 18 x 30 mm 1 105,00 €


Easy HandlingEpi-Guide can be perfectly cut to size for any defect using scissors or a scalpel. Once in contact with blood, the barrier matrix will become flexible and easily adaptable to the site. The structured embossed surface should face the soft tissue. The blood-soa-ked barrier matrix attaches closely to the tooth; in most cases, it will be un-necessary to hold the matrix in place with a suture.

Structure and CharacteristicsThe Epi-Guide barrier matrix comes in 18 x 30 mm (0.7 x 1.2 in.) rectangles. For easier orientation, the surface fa-cing the soft tissue has an embossed textured surface. Epi-Guide is highly hydrophilic and will accommodate a large amount of blood in the interme-diate chamber layer specifically desi-gned for this purpose. The patented three-layer barrier matrix contains a layer that prevents the ingrowth. of epithelial cells. In this manner, the bar-rier matrix serves as a placeholder for the development of bone and perio-dontal tissue. An evenly distributed blood clot is formed where the gin-giva, the barrier matrix, and the tooth tissue meet which counteracts flap recession and pocket formation.

Resorption BehaviorIt was shown in histological examina-tions performed six weeks postope-ratively that inflammation-free colla-gen fibers had formed in the barrier matrix. The archi-tecture and the structure of the barrier had remai-ned stable. After three weeks, as the formation of collagen fibers conti-nues, bioresorption sets in; the matrix,

however, continues to serve its function. After approxima-tely 12 months, Epi-Guide® will have been completely resorbed. No second-sta-ge surgery is required. Sutu-re dehiscences and a slight gingival recession are very well tolerated by Epi-Guide . The membrane surface with its open and interconnected pores counteracts suture

dehiscences and gingival recession.

Function and ApplicationFollowing careful preparation of the implant site (granulation tissue must be removed), scissors or a scalpel are used to trim the Epi-Guide membra-ne to size, making sure that the defect is sufficiently covered. The material should overlap the defect by 2-3 mm each on the mesial, distal, and api-cal aspects, but not on the coronal aspect. The embossed side is desi-gned to face away from the tooth sur-face so that the flat side of the barrier matrix attaches to the tooth surface. As soon as the Epi-Guide® membra-ne is exposed to blood, it will become very sticky. A suture will not be neces-sary in most situations, although the surgeon may certainly provide one at his or her discre-tion.

BiocompatibilityEpi-Guide consists of lactic acid poly-mers. The polymer structure (D, D-L, L-polylactide) breaks down into carbon di-oxide (CO ) and water (H O). That polylactic acid (PLA) is safe and innocuous has been demonstra-ted in numerous toxicological stu-dies and in vitro and in vivo studies of biocompatibility on several animal species as well as in-vivo studies on humans. PLA is an immunologically

inactive sub-stance. Because of their biological and mechanical proper-ties, PLA polymers have been used for widely divergent therapeutic ap-plications for many years, invariably demonstrating their biocompatibility, bio-logical resorption ability, and ab-sence of toxicity.

Clinical Use inPeriodontal Surgery (GTR)Treatment of a Class II furcation de-fect at a molar site using an Epi-Gui-de® membrane with surgical re-entry twelve months post-operatively:

Clinical Use in GBRA sufficient volume of healthy tooth substance is one of the most impor-tant pre-requisites for the successful insertion of dental implants. An insuffi-cient bone supply is an absolute con-traindication. The use of the barrier matrix makes it possible to succes-sfully regenerate bone and to rebuild atrophied alveolar ridges. Treatment of extraction sockets: In a 67-year-old male patient wearing a three-unit bri-dge, abutments 44 and 46 were se-ve-rely periodontally involved and had to be extracted Following the extraction there was a great amount of bone loss on the buccal aspects of both the premolar and the molar extraction sockets (Figure 2). The gra-nulation tissue was removed and the cortical bone layer roughened. Then the defect was filled with a mixture of bone replacement material and au-to-genous bone and covered with Epi-Guide® The augmented region was covered with a connective-tissue flap, followed by primary closure. Sur-gical re-entry after six months showed a significant amount of newly formed bone. The Epi-Guide® membrane had been resorbed completely.

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9310000030 10x10x10 mm 30 30,00 €

9360000005 50x10x10 mm 5 27,00 €

STYPRO® EMOSTATICO


Implantable resorbable gelatinespongefor instant haemostatic control

Technologically advanced biomaterial

Stypro® haemostatic spongeTopical haemostat for complete haemostasis. Technologically advanced biomaterial. An im-plantable, resorbable, gelatine sponge for in-stant management of haemocoagulation, the first step towards successful tissue repair and natural wound healing. Stypro® is an EC-certified Class III medical device and, as such, compliant with the Medical Device Directive 93/42 EEC. Stypro® is a gelatine sponge of porcine origin used in surgery when conventional procedures prove ineffective or impractical for management of haemostasis. Stypro® promotes the aggregation of platelets, accelerating the process of coagulation. Com-ponents within the blood interact with the large

surface area of the sponge, impregnating its po-rous structure and activating the natural process of platelet adhesion and the consequent process of coagulation

Stypro®: displays excellent shape retention; is easy to mould and shape; is implantable and com-pletely resorbable; is free from porcine endoge-nous retroviruses; is useful in procedures for tissue repair; is soft and malleable; can be used dry or impregnated with sterile saline solution; is com-pletely resorbed within three weeks.

Stypro®: absorbs elevated quantities of liquid (up to 50 times its weight); is free from any known risk of TSE transmission; demonstrates a rapid haemo-static effect (without the addition of exogenous thrombin); exhibits optimal porosity which impro-ves interconnectivity; exhibits excellent tolerance and biocompatibility.

Store Stypro® between +10°C and +25°C. Ensure packaging is not damaged and use immediately after opening. The product must not be resteri-lised. Use Stypro® under sterile conditions in a controlled environment.

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Code Description Q.ty Price

6000161 Titanium pin-setting 1 55,00 €

6000162 Steel pin-setting 1 45,00 €

6000163 Steel handle forpin-setting instruments 1 50,00 €

6000164 Extraction key 1 45,00 €

6000165 Steel container for pin 1 130,00 €


6000166 3-mm titanium pin 5 75,00 €

6000167 3-mm titanium pin 10 150,00 €

6000168 5-mm titanium pin 5 75,00 €

6000169 5-mm titanium pin 10 150,00 €

6000170

Complete kit comprising: 6000161, , 162, 163, 164,

and 165 and 15 pins of the client’s choice from 3mm

and 5mm dimesions

1 550,00 €

Fixation systemnon resorbable titanium pins

Ti-System is a fixation system for foil and membranes. The titanium pins combine all the handling benefits of tack fixation with the advantages of screw systems. The pins can be set in the bone quickly but safely and pre-cisely, without pre-drilling. They can subsequently be removed quickly and gently using the hexagonal key

supplied. The screw thread under the head and the perfectly engineered fit with the key make the entire process straightforward. Ti-System offers a simple and convenient method for rapid, safe fixation of foils and mem-branes used in bone regeneration surgery and their subsequent removal.

The pins (which are made of grade 5 titanium alloy) are available in two len-gths: 3 mm, for use in normal bone, and 5 mm for use in particularly soft bone tissue. The pins are subjected to electrochemical passivation, which renders them completely bioelectri-cally neutral and thus able to assist with the healing and regeneration of the bone without causing irritation.

The supplied Steribox is an important component of the Ti-System kit. It is used both for storing the instrumen-ts and in the sterilisation process. All Ti-System components can be orde-red separately: both sizes of pin (3 mm or 5 mm) are available in packages of 5 or 10.

The Ti-System set includes:10 x 3-mm pins and 5 x 5-mm pins; 1 pin setting instrument with titanium tip; 1 Steribox for the pins; hexagonal key.

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6000171 Inion tacks set (applicator + 4 tacks) 1 150,00 €

6000172 Inion tacks (4 tacks) 1 125,00 €

Descriptions, code,prices

Resorbable iniontacks

A simple, quick and safe fixation sy-stem for all forms of membrane used in bone-augmentation surgery. The Inion tacks are particularly easy to remove and can be inserted easily and safely by applying slight pressure to the sin-gle-use applicator included with the

tack set. The stainless-steel drill, also included, achieves optimal insertion depth. The drill can be sterilised and is therefore reusable. The synthetic tacks are made from L-lactic acid, D-lactic acid, and trimethylene carbonate. The heads exhibit excellent flexibility and

the tacks are completely resorbable. They are particularly indicated for the fixation of resorbable membranes.

Naturally, a reusable, stainless-ste-el applicator is also available. The tacks can be purchased separately in packets of four.

The tack set includes:4 x Inion tacks1 x single-use applicator in plastic1 x reusable drill in stainless steel

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3987 Safescraper Twist curve version 3 126,00 €


Safescraper TWIST provides an easy method to obtain ideal autologous cortical bone for grafts in any type

of defects with a minimally invasive te-chnique.

Easy to use

Safescraper TWIST makes autologous bone always available in any condi-tion, both for small and large harvests. The exclusive cutting performance of the blade allows cortical shavings to be collected, while preserving maxi-mum cell vitality, which is essential for graft integration. The bone collected is already combined with blood and ready to be positioned in the defect, or it can be temporary maintained in aseptic conditions in the transparent chamber.

Benefits of the device

Ready to use the disposable device is presented in individual sterile packa-ges. Its sterility in an undamaged package is guaranteed for 3 years

Minimally invasive

the manual harvesting technique is non-traumatic and well tolerated by

the patient

Useful

cortical bone can be harvested from any intraoral site, including near to the bone defect

Versatile

it is the ideal device for both extensive and minor harvesting procedures. Its curved tip version facilitates access in

all intraoral donor sites courtesy of Dr. Ferdinando D’Avenia (Italy).

Properties of the cortical graft

High cells vitality

The manual harvesting technique pre-serves the cellular component of the graft. The cortical shavings obtained by the Safescraper TWIST blade con-tain living and well-preserved bone cells, particularly osteocytes (mean vitality: 45-72%), but also osteoblasts, osteoclasts and osteoprogenitor cel-ls.

Ideal morphology

The cortical bone obtained with Safe-scraper TWIST looks like a elongated and convoluted shaving of a mean length of 1.3 mm and thickness ran-ging between 150 and 250 µm

The gold standard in intraoral bone harvesting

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4049Single use device in sterile single

package. Sterility for 3 years unopened

1 55,00 €


The experience has acquired in developing bone harvesting systems Safescraper has allowed the realization of Micross: a throwaway minimally invasive disposable device indicated in case of manual cortical bone harvesting. The excellent cutting performance, due to Micross exclusive micro-blade, allows an easy autologous collection even in narrow and hard to reach areas, near to the bone defect. The manual harvesting technique warrants the best preservation of cell vitality of the cortical tissue, a fundamental characteristic that allows the best

graft integration and reduces reabsorption activity.

The only instrument for the Tunnel harvesting technique Micross is the only bone harvesting device specifically studied for tunnel surgical techniques that minimize post-operation discomfort. The external diameter of the cannula is 5mm and due to its particular shape the instrument can be inserted in tissue tunnels in the intraoral area as the external oblique line, the cortical palatine and the zygomatic process.

Clinical application Micross allows the harvest of the

strictly necessary measure of bone tissue for the treatment of minor periodontal and peri-implant defects, permitting to avoid the use of bone substitutes.

By using Micross the bone tissue is directly collected in the chamber inside the cannula and it gets an excellent biological plasticity, because of the presence of coagulated blood. The volumizing effect, due to the curly morphology of the collection, reduces the quantity of bone needed to fill the defect and as a consequence it minimizes invasiveness for the patient.

Making the bone harvesting a handy procedure

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9003100006 Smartscraper 3 136,00 €


Smartscraper, the new generation of instruments for intra-oral bone collection which enables the clinician to use a single instrument, with a blade for the bone collection and a syringe for immediate grafting of the collected particulate

Advantages of the Smartscraper

Unique the small size of the spout (3mm) means that the syringe can be used to insert the bone particulate in the transcrestal sinus lift and in defects where access is restricted.

Versatile one instrument contains the blade

for harvesting the bone particulate and the syringe for positioning the particulate in the defect.

Rapid the double use of the instrument reduces surgical times and the management of various instruments used in the traditional techniques.

Minimally invasive the manual collection method is not traumatic and is well tolerated by the patient.

Flexible enables collection of cortical bone in all intra-oral locations, including in proximity of the defect, for both large quantities and small collections.

Economical enables intra-oral collection of the strictly necessary quantity while avoiding use of other substitutes up to 0.3 cc of bone.

Ready to use single-use instrument in a single sterile pack. In a properly closed pack sterility is guaranteed for 3 years.

The instrument is opened with a simple movement; the syringe in which the bone particulate has been collected enables positioning of the graft in the less accessible areas and simplifying the surgical procedure.

All in One, from collection to graft

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Cones formulated from equine collagenwith or without antibiotic protection

Following an extraction, the alveolus may not heal in an optimal manner wi-thout certain treatments. This can lead to insufficient reformation of bone tissue for secure implant placement, and immediate retreat of the alveolar ridge. It is therefore necessary that the alveolar ridge be reconstructed before an implant is installed.

1. Safe, rapid haemostasis. No risk of secondary haemorrhage. Stabilisation

Parasorb® HD Cone and Genta-Coll® are supplied sterile packed and are available in the following package sizes:

MK10 Genta-Coll® HD Cone [10 cones] • ø1.2 cm, h 1.6 cm

MK11 Genta-Coll® HD Cone [5 cones] • ø1.2 cm, h 1.6 cm

DK-10101 Parasorb® HD Cone [10 cones] • ø1.2 cm, h 1.6 cm

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Genta-Coll Hd Cone

Code Quantity Price

MK10 10 cone 170,00 €

MK11 5 cone 115,00 €

PARASORB® Hd Cone

Code Quantity Price

DK-1010 10 cone 90,00 €


of the blood clot with optional anti-biotic protection for patients at risk (e.g. smokers, patients with diabetes, patients with compromised immunity).

2. Reduction of atrophy in alveolar ridge. Stabilisation of the alveoli and preservation of the vestibular lamella. Maintenance of volume in the alveolar process Improved long-term aesthe-tic outcome and functionality.

3. Reliable bone regeneration. Defi-ned matrix for regeneration. Angio-conductive and osteoconductive. Formation of stable bone support for implant in a relatively short timescale. Greater confidence of positive long-term aesthetic outcome and functio-nality.

4. High levels of patient and practitio-ner satisfaction. Simple, safe applica-tion. Simplification of later treatment phases. Increased patient comfort.

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A combination of two teseted experimental prototypes membrane and collagen cone

Experiences with Parasorb®Sombrero:

“To date, our experience of using the ‘sombrero’ has been overwhelmingly positive. Neither adapting it for indi-vidual characteristics nor handling it in a treatment situation have presented problems. Use of the product leads to reliable bone healing in the alve-olus with stable epithelial coverage, two indispensable conditions for the

siting of an implant, for maxillofacial surgery or for an operation leading to a subsequent prosthetic intervention.”

Prof. Dres. J. Kleinheinz,

Clinic and Outpatient Clinic for Cra-nio-Maxillofacial Surgery

University Hospital Muenster (Universi-tätsklinikum Münster)

Parasorb Sombrero® is supplied sterile packed and is available in the following package sizes:

Package containing 1 cone membrane (code RD0001)

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Code Quantity Price

RD0001 1 cono 130,00 €

The membrane’s barrier effect pre-vents the ingrowth of connective tis-sue while its structure enables the growth of neo-formation bone cells and rapid development of an epithe-lial covering. The “Saliva-proof” seal provides protection from infection.

The cone stabilises the blood clot and the alveolus, helping to preserve the delicate vestibular lamella. It provides the alveolar process with volumetric stability, displays osteoconductive

and angioconductive properties, fa-cilitates stable bone healing at the site of the alveolus and improves long-term aesthetic outcomes and functio-nality. The product is easy to handle, since the cone and membrane are well joined to one another. It offers a de-fined matrix for regeneration, forms a stable implant site in a relatively short time span, requires minimal peeling back of the gum bordering the alveo-lus (minimising trauma and prolonging the vitality of the tissue). The healing

phase proceeds without complica-tions. Parasorb Sombrero is comple-tely resorbable.

Indications:

• simultaneous protection and filling of the alveolus (socket preservation)• simultaneous protection and filling of defects as part of guided bone rege-neration (GBR)• treatment of alveoli and other bone defects.


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Features, advantages, indications

FEATURES:

Made with a synthetic material, it is composed of calcium and phosphate, both factors of bone mineral phase. It is well tolerated by the body without immune-mediated risk or risk of infection. Degree of interconnected porosity of 35% and β-TCP of 65%. Radiopaque. Granule size: 150-500 microns, 500-1000 microns, from 1000 to 2000 microns.

INDICATIONS:

• Peri-implant defects.• Split creast.• Post-extraction cavities.

ADVANTAGES:

• No mechanical irritation of the surrounding tissues.• Intergranular spaces facilitating bone formation.• Complete reabsorbtion.

CERASORB® CLASSIC

FEATURES:

The level of interconnected porosity is of 65% and β-TCP of 35%. The granule structure is irregular and polygonal. This structure provides a great stability and impedes micro-movements of the material. It results less Radiopaque.Granule size: 150-500 microns, from 1000 to 2000 microns.

INDICATIONS:

• Periodontal defects.• Peri-implant defects.• Sinus lift.• Mini sinus lift.• Split creast.• Post implant bone regeneration.

ADVANTAGES:

• No mechanical irritation of surrounding tissues.• Intergranular spaces facilitate bone formation.• Complete reabsorption.

CERASORB® M

FEATURES:

Specifically studied for periodontal defects, it is made of polygonal granules which form a stable agglomerate. It has a good reabsorbtion rate. Its porosity of 25% and 75% of β-TCP is quickly reabsorbed. It is very Radiopaque.Granule size: 63-250 microns, 250-500 microns.

INDICATIONS:

• Periodontal defects

ADVANTAGES:

• No mechanical irritation of surrounding tissues.• Intergranular spaces that favor bone formation.• Complete reabsorbtion.

CERASORB® PERIO

35

FEATURES:

Used with autologous bone grafts, its Plus formulation is ideal to decrease the physiological reabsorbtion. The newly formed bone has a better mineralization. Mixture rapport 1:1. Very Radiopaque.Granule size: 500-1000 microns.

INDICATIONS:

• Mixed with block grafts.• Mixed with autologous bone collect with Safescraper.• Vertical regeneration.

ADVANTAGES:

It combines the advantages of Cerasorb Classic and Cerasorb M.

CERASORB® PLUS

FEATURES:

Syringe ready to use; the synthetic granules Cerasorb M in hyaluronic acid matrix help the healing of the tissues. Completely reabsorbed. Radiopaque.Syringe 0,5 cc, Syringe 1 cc.

INDICATIONS:

• Contenitive defects 3-4 insides.

ADVANTAGES:

Syringe ready to use. Unneeded mixing with blood or physiologic material.

CERASORB® PASTE

FEATURES:

The Cerasorb Ortho Foam structure allows the three-dimensional regeneration of bone tissue. In close contact with vital bone, the synthetic bioactive ceramic material is reabsorbed by the body within the course of months and it is simultaneously replaced by newly formed bone. Radiopaque. Completely reabsorbed. 0.5 cc.

INDICATIONS:

Filling of the blisters; 2 or more insides.

ADVANTAGES:

Volume retention and effective support in bone reconstruction.

CERASORB® FOAM

FEATURES:

HA 95% β-TCP 5%. It is a synthetic hydroxyapatite. The product must be mixed with autologous blood. It can also be mixed with PRP and autologous bone. Granule size: 250-1000 microns, 1000-2000 microns.

INDICATIONS:

Periodontal defects; Peri-implant defects; Sinus lift; Mini sinus lift; Split creast; Post implant bone regeneration; Vertical regeneration; Horizontal regeneration.

ADVANTAGES:

It doesn’t contain any material of animal or human origin. Slowly resorbable, volume retention.

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FEATURES:

It is a membrane based on type 1 bovine collagen without crosslinking agents, translucent, elastic and flexible. It provides a good barrier effect; four-mnonths barrier effect is reabsorbed in 8 months. Dimensions: 15x20; 20x30; 30x40.

INDICATIONS:

• GTR• GBR

ADVANTAGES:

It does not require a second surgery to reopen. The dense, fibrous structure creates porosity in order to slow down the growth of epithelial cells and to preserve the gingival connective cell migration into the healing site.

FEATURES:

It is a membrane based on swine collagen. It has a high degree of purity, consisting in a network of collagen and elastin fibers, creating a protected space in the treating area by promoting and creating a barrier effect. The rough side facing the hard tissue acts as a guide for osteoblasts; the smooth side facing the soft tissue supports their recovery. Dimensions: 15x20, 25x30, 30x40.

INDICATIONS:

• For small or big defeats when needed a barrier effect• Schneider membrane protection• Hole protection lateral or crestal sinus lift• GTR• GBR fixed with pin

ADVANTAGES:

• Barrier effect• Excellent compatibility• Excellent moldability• High tensile strength• Combined with various grafting materials• Fixable with Pin or Screws

FEATURES:

It is a synthetic membrane, bio-resorbable based on polylactic acid. Tri-Layer technology: the first rough layer touches the mucous membrane, it is characterized by wide grooves. It inhibits the infiltration of fibroblasts facilitating cell adhesion. The interlayer, with a labyrinth structure, supports the formation of collateral vessels and the flow of interstitial fluid. It provides the stabilization of fibroblasts. The third layer is in direct contact with the osseus part; closed pores allow it to absorb blood and adhere to the tooth surface, promoting the gingival attachment. Dimensions: 18X30.

INDICATIONS:

• GTR• Furcations treatments Class II• Dehiscences

ADVANTAGES:

Slow reabsorbtion, barrier effect in 20 weeks. Complete reabsorption between six and twelve months; Unic tri-layer; It can be left exposed.

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FEATURES:

It is a swine gelatin sponge, implantable and resorbable for the immediate haematological control, accelerating the coagulation.It is reabsorbed in 3 weeks. Dimensions: 10x10x10 mm, 50x10x10 mm.

FEATURES:

Sterile single use, curved to be easy to use; Package 3 pieces.

FEATURES:

It is a complete fixing system of membranes, made of grids. Grade 5 titanium.Titanium applicator; steel applicator; steel applicator handle; screwdriver for extraction; steel box for pin; titanium pin 3mm; titanium pin 5mm.

FEATURES:

It’s a complete fixed system with resorbable pin. Syntetics L-lactic acid, D-lactic acid and Trimethyl carbonate. Very flexable. Inion Tacks set (applicator and 4 more tacks). Inion Tacks 4.

INDICATIONS:

• Small injuries.• Mini sinus lift with Cosci technique, shredded introduced in cavities as the

Schneider membrane protection.

INDICATIONS:

It allows to get easily and barely invasively cortical bone autograft. It can be used pure or mixed with synthetic or animal particles.

INDICATIONS:

To fix resorbable membranes and not, grids.

INDICATIONS:

It fixes reasorbable membrane with slow reabsorbtion.

ADVANTAGES:

• High capacity to absorb liquids up to 50 times its weight.• Low cost.

ADVANTAGES:

• Sterile single use.• Mini-invasive, non-traumatic for the patient.• Thanks to the curved version is possible to take cortical bone.• It is ideal for large and small amounts. • Bone chips

ADVANTAGES:

The titanium tacks combine all the benefits of the fixing handling with the screwing one.

ADVANTAGES:

It is not removable to avoid the second operation.

STYPRO® EMOSTATICO

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FEATURES:

• Sterile single use, external diameter 5mmPackage 1 piece

INDICATIONS:

• Allows to get easily and so minimally invasive cortical bone autograft.• Used pure or mixed with synthetic or animal particles.• Technical picking tunnel• Restricted areas.

ADVANTAGES:

• Mini-invasive device, easy even in restricted areas.• Levy for tunnel techniques that minimize the inconvenience to the patient. • Bone chips.

FEATURES:

• Sterile single use, two product in one• Package 3 pieces

INDICATIONS:

• It allows to get easily and so minimally invasive cortical autologous bone, and with convenient place syringe into the defect.

• It can be used pure or mixed with synthetic or animal particles.• Technical picking tunnel• Restricted areas

ADVANTAGES:

• Flexible, allows to obtain in a single instrument, the blade and syringe to place the material taken into the defect to be treated. The small size of the spout (3 mm) allows to place in small particulate defects.

• Bone chips

FEATURES:

• Collagen cones equine origin with antibiotic• Package 5 or 10 cones

INDICATIONS:

• Socket Presevertion.• Alveolus protection, filling and treatment.• Indicated for patients at risk (ex. diabetics, smokers, immunosuppressed)

ADVANTAGES:

• Quick and safe homeostasis• Clot stabilization with antibiotic protection• Reducing atrophy of the alveolar ridge

39

FEATURES:

• Cones in collagen of equine origin• Package 10 cones

FEATURES:

• It is the combination of two prototypes (membrane and collagen Cone)• Package 1 cone

INDICATIONS:

• Socket Presevertion• Alveulus protection, filling and treatment.

INDICATIONS:

• Socket presevertion• Protection and filling the alveolus and treatment of other defects

ADVANTAGES:

• Quick and safe homeostasis• Clot stabilization.• Enhancing aesthetics• Reducing atrophy of the alveolar ridge

ADVANTAGES:

• The barrier effect of the membrane prevents the intrusion of connective while its structure allows the growth of newly formed bone cells, and a fast epithelialization above it.

• It protects against infection.• Osteoconductive

Cat

_Reg

_Rev

C -

03/

2017

[email protected] | www.ires.dental

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