Reduction-Division Genetic Recombination 1. cell division GAMETES, HALF CHROMOSOMES, The form of...
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Transcript of Reduction-Division Genetic Recombination 1. cell division GAMETES, HALF CHROMOSOMES, The form of...
The form of cell divisioncell division by which GAMETESGAMETES, , with HALFHALF the number of CHROMOSOMESCHROMOSOMES, , are produced.
DIPLOIDDIPLOID (2n) (2n) HAPLOIDHAPLOID (n) (n) MeiosisMeiosis is SEXUALSEXUAL
reproduction.reproduction. TWOTWO divisions divisions (MEIOSIS IMEIOSIS I and
MEIOSIS IIMEIOSIS II).2
Sex cells divide to produce GAMETESGAMETES (sperm or egg)(sperm or egg).
Gametes have HALFHALF the # of chromosomes.
Occurs only in GONADSGONADS (testes (testes or ovaries).or ovaries).
Male: Male: SPERMATOGENESIS -SPERMATOGENESIS -spermsperm
Female: Female: OOGENESIS - OOGENESIS - egg or egg or
ovaova3
2n=46
humansex cell
diploid (2n)
n=23
n=23
Meiosis I
n=23
n=23
n=23
n=23
sperm
haploid (n)
Meiosis II4
2n=46
humansex cell
diploid (2n)
n=23
n=23
Meiosis I
n=23egg
Haploid (1n)
Meiosis II5
Polar Bodies (die)
Similar to mitosismitosis interphase. CHROMOSOMESCHROMOSOMES (DNA)(DNA) replicate in the S S
phasephase Each duplicated chromosomechromosome consist
of twotwo identicalidentical SISTER SISTER CHROMATIDS CHROMATIDS attached at their CENTROMERESCENTROMERES.
CENTRIOLECENTRIOLE pairs also replicate.
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Cell division Cell division that reduces the chromosome number chromosome number by one-half.one-half.
Four phasesFour phases:a.a. Prophase IProphase Ib.b. Metaphase IMetaphase Ic.c. Anaphase IAnaphase Id.d. Telophase ITelophase I
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Prophase IProphase I
LongestLongest and and most complex most complex phase (90%).phase (90%).
ChromosomesChromosomes condense. SynapsisSynapsis occurs - Homologous chromosomesHomologous chromosomes come togetherto form a tetradtetrad.
TetradTetrad is two chromosomestwo chromosomesor four chromatids four chromatids (sister and non-sister chromatids).
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•Homologs contain DNA that codes for the same genes , but different versions of those genes
•Genes occur at the same loci
Pair of chromosomeschromosomes (maternalmaternal and paternalpaternal) that are similar in shape similar in shape and sizeand size..
Homologous pairs ((tetradstetrads) carry ) carry GENES controlling the SAME inherited GENES controlling the SAME inherited traitstraits.
Each locuslocus (position of a gene) (position of a gene) is in the same position on homologues.
HumansHumans have 23 pairs 23 pairs of homologous homologous chromosomes:chromosomes:a. First 22 pairs 22 pairs of autosomesautosomes
b. Last pair of sex chromsex chromosomesosomes12
LOCLOCII
Crossing over Crossing over may occur between non-sister chromatidschromatids at sites called chiasmatachiasmata.
Crossing overCrossing over: segments of nonsister chromatidschromatids break and reattach to the other chromatidchromatid.
Chiasmata (chiasma) Chiasmata (chiasma) are where chromosomes touch each other and exchange genes exchange genes (crossing overcrossing over.)
Causes Genetic RecombinationGenetic Recombination
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• Nucleus & Nucleolus Nucleus & Nucleolus disappear
• SpindleSpindle forms
• Chromosomes coilcoil & SynapsisSynapsis (pairing) occurs
• TetradsTetrads form & Crossing over Crossing over Occurs
centriolesspindle fiber
asterfibers
19TETRADTETRAD
Shortest phase Tetrads align on the equator. Independent assortment occurs –
chromosomes separate randomly causing GENETIC RECOMBINATION
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Formula: 2n
Example:Example: 2n = 42n = 4 then then 1n = 21n = 2 thusthus 222 2 = 4= 4
combinations combinations
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In terms of In terms of Independent Independent AssortmentAssortment -how many -how many different combinations of different combinations of sperm could a sperm could a humanhuman malemale produce? produce?
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Formula: 2Formula: 2nn
Human chromosomes:Human chromosomes:2n = 462n = 46
n = 23n = 23 222323 = ~8 million = ~8 million combinationscombinations
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Homologous chromosomes Homologous chromosomes separate and move towards the poles.
Sister chromatids Sister chromatids remain attached at their centromerescentromeres.
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Each pole now has haploidhaploid (1n) set of chromosomeschromosomes.
CytokinesisCytokinesis occurs and two haploid daughter cells are formed.
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No Interphase II No Interphase II or very or very shortshort
No DNA ReplicationNo DNA Replication Remember: Meiosis II is Remember: Meiosis II is
similar to mitosissimilar to mitosis
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Same as Same as ProphaseProphase in in mitosismitosis
Nucleus & nucleolus disappearNucleus & nucleolus disappear Chromosomes condenseChromosomes condense Spindle formsSpindle forms
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Same as Same as TelophaseTelophase in mitosis. in mitosis. Nuclei and Nucleoli Nuclei and Nucleoli reform, spindle reform, spindle
disappearsdisappears CYTOKINESISCYTOKINESIS occurs. occurs. Remember: Remember: FOUR HAPLOID FOUR HAPLOID
DAUGHTER cells DAUGHTER cells are produced.are produced.
Called Called GAMETESGAMETES (eggs and sperm) (eggs and sperm)
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1n Sperm cell fertilizes 1n
egg to form 2n zygote
Also known as Also known as GENETIC GENETIC RECOMBINATIONRECOMBINATION
Important to population as the raw Important to population as the raw material for material for NATURAL SELECTION.NATURAL SELECTION.
All organisms are All organisms are NOTNOT alike alike StrongestStrongest “ “most fit” most fit” survive to survive to
reproduce & pass on traitsreproduce & pass on traits
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What are the What are the 33 sources of sources of genetic recombination genetic recombination or or variation? variation?
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1.1. CROSSING OVER CROSSING OVER (prophase (prophase I)I)
2.2. INDEPENDENT ASSORTMENT INDEPENDENT ASSORTMENT (metaphase I)(metaphase I)
3.3. RANDOM FERTILIZATIONRANDOM FERTILIZATION
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A cell containing 20 20 chromosomeschromosomes (diploid)(diploid) at the beginning of meiosis would, at its completion, produce cells containing how many chromosomeschromosomes?
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AAn organized organized picture picture of the chromosomes of a human arranged in pairs arranged in pairs by size by size from largest to smallest.
PPairs 1-221-22 called AUTOSOMESAUTOSOMES
LLast pair are SEX SEX CHROMOSOMESCHROMOSOMES
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Male - XYMale - XY
The fusion of a spermsperm and eggegg to form a zygotezygote.
A zygote is a FERTILIZED EGGFERTILIZED EGG
n=23egg
sperm n=23
2n=46zygote
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A cell containing 40 40 chromatidschromatids at the beginning of meiosis would, at its completion, produce cells containing how many chromosomeschromosomes?
46