Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during...

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Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation (Resolution 16) Ad Hoc Disease Transmission Advisory Committee (DTAC) Dr. Dan Kaul

Transcript of Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during...

Page 1: Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation (Resolution 16) Ad Hoc Disease.

Recognizing Seasonal and Geographically Endemic

Infections in Organ Donors: Considerations during Living

Donor Evaluation(Resolution 16)

Ad Hoc Disease Transmission Advisory Committee (DTAC)

Dr. Dan Kaul

Page 2: Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation (Resolution 16) Ad Hoc Disease.

Current policy requires testing for living donor from areas endemic for Strongyloides, Chagas (T. cruzi), and West Nile Virus.

 Living donor recovery hospitals are struggling with identification of risk factors and testing for these living donors.

The Problem

Page 3: Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation (Resolution 16) Ad Hoc Disease.

#4- Promote Transplant

Patient Safety• Minimize risk to living

organ donors• Properly evaluate

potential living donors

#5- Promote Living Donor

Safety• Increase capacity to

identify patient safety issues

Strategic Plan

Page 4: Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation (Resolution 16) Ad Hoc Disease.

Provide guidance to members regarding the development of a protocol for identifying and testing potential living donors for seasonal and geographically endemic disease.

Goal of the Proposal

Page 5: Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation (Resolution 16) Ad Hoc Disease.

Highlights six “frequently” seen infections of this type based upon review of DTAC experience, existing literature and materials available on the CDC website

Format easily digestible for any member of transplant team using tables, maps, and text

How the Proposal will Achieve its Goal

Page 6: Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation (Resolution 16) Ad Hoc Disease.

Product Guidance Document

Target Population Impact: Living Donors (though it helpful to OPO staff as well)

Total IT Implementation Hours 0/10,680

Total Overall Implementation Hours 20/17,885

Overall Project Impact

0 1000 2000 3000 4000 5000

Series1

0 1000 2000 3000 4000 5000 6000

Se-ries1

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Histoplasmosis

Coccidioidomycosis

Chagas (T. cruzi)

Strongyloides

Tuberculosis

West Nile Virus

Specific Infections Included:

Page 8: Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation (Resolution 16) Ad Hoc Disease.

Risk factors to consider

Who should be screened

How to screen

Management of infected living donor

Management of recipients

Infection avoidance between testing and transplant

Guidance Includes:

Page 9: Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation (Resolution 16) Ad Hoc Disease.

RESOLVED, that the guidance document entitled “Recognizing Seasonal and Geographically Endemic Infections in Organ Donors: Considerations during Living Donor Evaluation,” as set forth in Exhibit C, is hereby approved, effective November 13, 2014.

Resolution 16 (page 49)