ReaMetrix Product Catalog 2010

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    1585 Industrial RoadSan Carlos, CA 94070USAPhone : +1 650 620 9253

    Fax : +1 650 620 0093

    50-B, II PhasePeenya Industrial AreaPeenya, Bangalore 560058, IndiaPh: +91-80-28378693/5Fax: +91-80-41172451

    E-mail: [email protected]: www.reametrix.com

    ReaMetrix help us in keeping our commitmentin oering tests at aordable costs especially HIV.We have so far conducted hundreds of tests andhave obtained accurate and reproducible results.The availability of these reagents at this very af-

    fordable price point has allowed us to signicantlyreduce the cost of these tests to the patient.

    Dr. Sujay Prasad, Director, Anand Diagnostics

    With the new concept of dried reagents a samplecan be added to the reagent tube where the sampleis collected. The sample integrity is maintainedupto a week at temperatures upto 40C. This givesus tremendous exibility in the way samples canbe handled.

    Dr.Anjali Kale, Head Reference Laboratory,Dr Lal Pathlabs

    ISO 9001:2008certifed company

    www.reametrix.com

    ReaMetrixAccelerating Innovation

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    Company

    ReaMetrix, Inc. is a nextgeneration biotechnologycompany that was founded withthe unique business model ofusing the labor cost arbitragethrough India to create signi-cant and sustainable

    value arbitrage. As with theearly Silicon Valley entrepre-neurs, we are working to build acompany culture that providestalented Indian scientists withan environment where they havefreedom to exercise their train-ing, skills and imagination whilebuilding corporate value. Ouregalitarian approach allows us toencourage and reward initiativethroughout our organization.Our people are the key to oursuccess.

    The challenge of technological inno-vation is to create solutions that arelocally aordable and sustainable inthe long run within the local macro-economic constraints. The solutions

    should permit generation of localeconomic activity that will reinforcelong-term economic sustainability.

    Bala S. Manian, CEO ReaMetrixInc..Aordable DiagnosticsChang -ing the Paradigm in India. Cytometry

    Part B (Clinical Cytometry) 74B(Suppl. 1):S117S122 (2008)

    Process is our Product

    At ReaMetrix, we have built aworld-class research and devel-opment facility in Bangalore,India with a primary focus ofapplying Six Sigma product de-velopment strategies to diagnos-tic and life science products. We

    believe that process control is acritical component of generatinghigh quality data and products.Our corporate infrastructureis process-centric, and we liveby our philosophy on a dailybasis. Rigorous documentation,full audit trails, and a dedicatedquality group result in high qual-ity products, and reproducible,trustworthy data. At ReaMetrix,Process is our Product.

    ReaMetrix is committed tobecoming the leading provider ofhigh quality research and diag-nostic assay solutions resultingin a transformation of the costopportunities available in Indiainto value for both the biotech-

    nology and global health sectors.

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    HIV Immunophenotyping

    Reagents forDiagnostic Use

    CatalogNumber

    Product/Reagent

    IntendedUse

    Format Storage KitSizes

    25118-00 Dry Tri T-STAT

    CD3/CD4/CD8 Reagent *

    Dry Room

    Temperature

    50For determining absolute counts of human

    total T, helper/inducer & suppressor/cytotoxicT lymphocytes in erythrocyte-lysedwhole blood

    25197-00 Dry Tri T-STATCD3/CD4/CD45 Reagent

    Dry RoomTemperature

    50For determining absolute lymphocyte count(ALC), percentages & absolute counts of hu-man total T and helper/inducer T lymphocytesin erythrocyte-lysed whole blood

    25239-00 ReaPan 34845Reagent

    Dry RoomTemperature

    50For determining ALC, percentages and absolutecounts of human total T, helper/inducer &

    Suppressor/cytotoxic T lymphocytes in eryth-rocyte-lysed whole blood

    25244-00 ReaPan 3 4 GReagent

    Dry RoomTemperature

    50Reagent For determining absolute counts ofhuman total T, helper/inducer T lymphocyteson Guava Platform

    25332-00 ReaPan 3 8 GReagent

    Dry RoomTemperature

    50For determining absolute counts of humantotal T, suppressor/cytotoxic T lymphocyteson Guava Platform

    25124-00 Rea T-Count CD4/CD3 & CD8/CD3(Dual tube) Reagent

    Dry RoomTemperature

    50For determining absolute counts of human to-tal T, helper/inducer & suppressor/cytotoxic Tlymphocytes in erythrocyte-xed whole bloodon BD FACSCount platform

    25242-00 Rea T Count CD4/CD3 (Single Tube)Reagent

    Dry RoomTemperature

    50For determining absolute counts of humantotal T, helper/inducer T lymphocytes inerythrocyte-xed whole blood onBD FACSCount platform

    Decentralized Staining Concept

    Blood samples from collectioncentres that operate in resourcepoor settings, age by the time asthey are shipped to c entralizedtesting facilities. CD receptors areknown to undergo a process calledcapping (internalization of

    receptors), with sample ageing.

    Dry reagents enable staining tobe done in collection centres thattypically have no electricity torun refrigeration units. Stainedsamples can then be transportedwithout the need for cold chain.

    The decentralized approach tosample processing mitigates therisk associated with variation incell counts. Studies on samplesstained and xed using dry re-

    agents have shown that there is nodrop in staining intensity or cellcount upto 8 days when stored atroom temperature.

    Regulatory Status

    ReaMetrix Reagents conform tohighest international standardsof quality. Most of the diagnosticreagents are CE marked and/orFDA cleared. For details, please

    contact us.

    * For In Vitro Diagnostic Usein the United States

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    Reagents forDiagnostic Use

    25238-00 ReaPan

    B27

    Dry RoomTemperature

    25For detection of HLA-B27 antigen expressionin erythrocyte-lysed whole blood (LWB) using

    ow cytometry

    25323-00 ReaPanS34

    Dry RoomTemperature

    25For enumeration of Hematopoietic stem cellsCD34+ in human peripheral or mobilized bloodsamples, umbilical cord blood samples, bonemarrow samples and leukapheresis samples byow cytometry

    25329-00 ReaPan

    Micro

    Dry Room

    Temperature

    50For screening of Urine samples for presence/

    absence of bacteria by ow cytometry

    25108-00 ReaCountTubes

    Dry RoomTemperature

    50Absolute Counting Fluorescent Beads-Providesabsolute counts for immunophenotyping

    CatalogNumber

    Product/Reagent

    IntendedUse

    Format Storage KitSizes

    Hematopoietic CD34+ Stem Cell Enumeration

    Presence/Absence test for Bacteria in Urine

    ReaCount Tubes

    HLA B-27 Typing

    ReaPan S34: Ease in Workfow

    ReaMetrix Stem cell enumera-tion reagents are provided in oneready-to-use reagent dried tube.The assay just needs additionof sample, simplifying samplepreparation. Incubation time is 30minutes, speeding time to results;

    a boon to diagnostic labs thatprocess multiple samples simulta-neously. Predispensed uorescencereference beads included in thereagent tube, ensure accurateenumeration of CD34+ cellsinterest. The result: more ecientworkow and greater condencein results.

    ReaMetrix HLA B27 reagent:Enabling Reduced HLA-B7 CrossReactivity

    The only existing owcytometry based reagent featuringtwo antibodies against the HLA-B27 antigen. The result: increasedSensitivity. The reagent use anti-B7antibody against HLA-B7 antigen,which ensures minimal cross reac-tivity thus reducing the number offalse positives. The result: higherSpecicity. The reagent usesbuilt-in intensity controls in each

    test making the assay highly ro-

    bust and independent of externalstandards.

    Regulatory Status

    ReaMetrix Reagents conform tohighest international standardsof quality. Most of the diagnosticreagents are CE marked and/orFDA cleared. For details, pleasecontact us.

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    Reagents forResearch Use

    25347-00 Anti CD3-Atto488/CD4-

    PE-DyLight 594/CD8-PE/CD45-PerCP Reagent

    Dry RoomTemperature

    50For determining ALC, percentages and absolutecounts of human total T, helper/inducer

    & Suppressor/cytotoxic T lymphocytes inerythrocyte-lysed whole blood on BeckmanCoulter 4 colour EPICS-XL Instrument

    25384-00 Anti CD45-Atto 488/ CD4-PE reagent

    Dry RoomTemperature

    50For determining ALC, percentages and absolutecounts of human helper/inducer T lympho-cytes in erythrocyte-lysed whole blood

    25348-00Anti CD41-Atto488 &CD61-Atto488 reagentwith AbsoluteCounting Beads

    DryRoom

    Temperature50For determining absolute counts of human

    platelets in stained-xed whole blood

    25387-00 7-Amino-actinomycin D( 7-AAD) nucleic acid dyeready-to-use solutionwith Absolute CountingBeads

    Liquid 2-8 C 25For enumeration of residual leucocytes inLeuco reduced blood products

    25381-00 Anti CD235ab-Dy649/Thiazole Orange re-agent with AbsoluteCounting Beads

    Dry RoomTemperature

    50For determining percentages and absolutecounts of human reticulocytes and absolutecount of erythrocytes using Flow Cytometry

    CatalogNumber

    Product/Reagent

    TypicalUsage

    Format Storage KitSizes

    Human Platelets Enumeration

    Residual Leucocytes Enumeration

    Human Reticulocyte Enumeration

    HIV Immunophenotyping

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    Reagents for Research Use

    ReaMetrix Multicolor Immunophenotyping Reagents(Leukemia-Lymphoma Panel)

    ExcitationLaser (nm)

    EmissionMaximum (nm)

    488 488 , 532 488 , 532 488 , 532 488 595, 633,635, 647

    595, 633,635, 647

    488, 532, 561

    523 578 618 676 678660 660

    785

    AntibodiesAtto-488(FITC Equivalent)

    Phycoerythrin(PE)

    PE-DyLight 594(PE-Texas Redequivalent)

    PE-Dyomics 649(PE-Cy5 equivalent)

    PerCP APCPE-HiLyte 750(PE-Cy7 equivalent)

    APC-HiLyte 750(APC-Cy7 equivalent)

    CD2

    CD3

    CD4CD5

    CD7

    CD8

    CD10

    CD11b

    CD13

    CD14

    CD15

    CD16

    CD19

    CD20

    CD22

    CD23

    CD25

    CD33

    CD34

    CD36

    CD38

    CD41

    CD45

    25802-01

    25803-01

    25804-0125805-01

    25807-01

    25808-01

    25810-01

    25811-01

    25813-01

    25814-01

    25815-01

    25816-01

    25819-01

    25820-01

    25822-01

    25823-01

    25825-01

    25833-01

    25834-01

    25835-01

    25838-01

    25841-01

    25845-01

    25802-02

    25803-02

    25804-0225805-02

    25807-02

    25808-02

    25810-02

    25811-02

    25813-02

    25814-02

    25815-02

    25816-02

    25819-02

    25820-02

    25822-02

    25823-02

    25825-02

    25833-02

    25834-02

    25835-02

    25838-02

    25841-02

    25845-02

    25802-08

    25803-08

    25804-0825805-08

    25807-08

    25808-08

    25810-08

    25811-08

    25813-08

    25814-08

    25815-08

    25816-08

    25819-08

    25820-08

    25822-08

    25823-08

    25825-08

    25833-08

    25834-08

    25835-08

    25838-08

    25841-08

    25845-08

    25802-03

    25803-03

    25804-0325805-03

    25807-03

    25808-03

    25810-03

    25811-03

    25813-03

    25814-03

    25815-03

    25816-03

    25819-03

    25820-03

    25822-03

    25823-03

    25825-03

    25833-03

    25834-03

    25835-03

    25838-03

    25841-03

    25845-03

    25802-04

    25803-04

    25804-0425805-04

    25807-04

    25808-04

    25810-04

    25811-04

    25813-04

    25814-04

    25815-04

    25816-04

    25819-04

    25820-04

    25822-04

    25823-04

    25825-04

    25833-04

    25834-04

    25835-04

    25838-04

    25841-04

    25845-04

    25802-05

    25803-05

    25804-0525805-05

    25807-05

    25808-05

    25810-05

    25811-05

    25813-05

    25814-05

    25815-05

    25816-05

    25819-05

    25820-05

    25822-05

    25823-05

    25825-05

    25833-05

    25834-05

    25835-05

    25838-05

    25841-05

    25845-05

    25802-06

    25803-06

    25804-0625805-06

    25807-06

    25808-06

    25810-06

    25811-06

    25813-06

    25814-06

    25815-06

    25816-06

    25819-06

    25820-06

    25822-06

    25823-06

    25825-06

    25833-06

    25834-06

    25835-06

    25838-06

    25841-06

    25845-06

    25802-07

    25803-07

    25804-0725805-07

    25807-07

    25808-07

    25810-07

    25811-07

    25813-07

    25814-07

    25815-07

    25816-07

    25819-07

    25820-07

    25822-07

    25823-07

    25825-07

    25833-07

    25834-07

    25835-07

    25838-07

    25841-07

    25845-07

    PackSizes

    25 Tests100 Tests

    Using its own unique dr ied down reagent technology, ReaMetrix canmix and match a ntibodies and uorophores to create specic multicol-or dried down L-L panels of reagents as per customers requirements.

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    ExcitationLaser (nm)

    EmissionMaximum (nm)

    488 488 , 532 488 , 532 488 , 532

    523 578 618 676

    AntibodiesAtto-488(FITC Equivalent)

    Phycoerythrin(PE)

    PE-DyLight 594(PE-Texas Redequivalent)

    PE-Dyomics 649(PE-Cy5 equivalent)

    CD55

    CD56

    CD59CD61

    CD64

    CD73

    CD79a

    CD90

    CD103

    CD105

    CD117

    HLA-DR

    Kappa

    Lambda

    IgM

    TCR

    TCR

    MPO

    FMC7

    Mouse IgG1,

    Mouse IgG2a,

    Mouse IgG2b,

    Mouse IgG3

    25855-01

    25856-01

    25859-01

    25861-01

    25864-01

    25873-01

    25879-01

    25890-01

    25903-01

    25905-01

    25917-01

    25750-01

    25751-01

    25752-01

    25753-01

    25754-01

    25755-01

    25756-01

    25757-01

    25758-01

    25759-01

    25760-01

    25761-01

    25855-02

    25856-02

    25859-02

    25861-02

    25864-02

    25873-02

    25879-02

    25890-02

    25903-02

    25905-02

    25917-02

    25750-02

    25751-02

    25752-02

    25753-02

    25754-02

    25755-02

    25756-02

    25757-02

    25758-02

    25759-02

    25760-02

    25761-02

    25855-08

    25856-08

    25859-08

    25861-08

    25864-08

    25873-08

    25879-08

    25890-08

    25903-08

    25905-08

    25917-08

    25750-08

    25751-08

    25752-08

    25753-08

    25754-08

    25755-08

    25756-08

    25757-08

    25758-08

    25759-08

    25760-08

    25761-08

    25855-03

    25856-03

    25859-0325861-03

    25864-03

    25873-03

    25879-03

    25890-03

    25903-03

    25905-03

    25917-03

    25750-03

    25751-03

    25752-03

    25753-03

    25754-03

    25755-03

    25756-03

    25757-03

    25758-03

    25759-03

    25760-03

    25761-03

    488 595, 633,635, 647

    595, 633,635, 647

    488, 532, 561

    678660 660

    785

    PerCP APCPE-HiLyte 750(PE-Cy7 equivalent)

    APC-HiLyte 750(APC-Cy7 equivalent)

    25855-04

    25856-04

    25859-0425861-04

    25864-04

    25873-04

    25879-04

    25890-04

    25903-04

    25905-04

    25917-04

    25750-04

    25751-04

    25752-04

    25753-04

    25754-04

    25755-04

    25756-04

    25757-04

    25758-04

    25759-04

    25760-04

    25761-04

    25855-05

    25856-05

    25859-05

    25861-05

    25864-05

    25873-05

    25879-05

    25890-05

    25903-05

    25905-05

    25917-05

    25750-05

    25751-05

    25752-05

    25753-05

    25754-05

    25755-05

    25756-05

    25757-05

    25758-05

    25759-05

    25760-05

    25761-05

    25855-06

    25856-06

    25859-0625861-06

    25864-06

    25873-06

    25879-06

    25890-06

    25903-06

    25905-06

    25917-06

    25750-06

    25751-06

    25752-06

    25753-06

    25754-06

    25755-06

    25756-06

    25757-06

    25758-06

    25759-06

    25760-06

    25761-06

    25855-07

    25856-07

    25859-07

    25861-07

    25864-07

    25873-07

    25879-07

    25890-07

    25903-07

    25905-07

    25917-07

    25750-07

    25751-07

    25752-07

    25753-07

    25754-07

    25755-07

    25756-07

    25757-07

    25758-07

    25759-07

    25760-07

    25761-07

    PackSizes

    25 Tests100 Tests

    This concept is suited to diagnostic labs that process multiple samplessimultaneously. This approach can be used to standardize panels (anti-bodies and uorophores) across various laboratories so that there canbe an unbiased discussion of the results of immunophenotyping.

    Reagents for Research Use

    ReaMetrix Multicolor Immunophenotyping Reagents(Leukemia-Lymphoma Panel)

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    ReagentAccessories

    CatalogNumber

    Product/Reagent

    TypicalUsage

    Format Storage KitSizes

    Accessories for Diagnostic Use

    25237-00 ReaLyse lysing Solution

    (10X Concentrate)

    Liquid RoomTemperature

    50

    ml

    Erythrolytic reagent intended for lysing redblood cells to enable a lyse-no wash protocol

    25326-00 ReaFix

    Diluent Solution)Liquid Room

    Temperature

    Diluent solution used for dilution of Lysingsolution & Fixative solution

    25325-00 ReaFix Fixative Solution(5% Formaldehyde)

    Liquid RoomTemperature

    50

    ml

    Fixative solution intended for the xation ofcell preparations

    25108-00 ReaFlow Liquid RoomTemperature

    4 cans(each 5 l)

    Buered sheath uid meant for use on mostow cytometer systems.

    25108-00 ReaQuant Dry RoomTemperature

    25

    Tests

    Assay control reagent kit that includes Low,Medium, and High control beads (and ifneeded Zero control bead tube) for use insetting up the BD FACSCount instrument andchecking linearity.

    50

    ml

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    OtherServices

    Design of Research Reagents

    Custom Conjugation Services

    Custom Cell Line Development Services

    Bead Based FLISA Assay

    Bead Based FLISA for Quantita-tive Estimation of Antigen Con-centrations by Flow Cytometrytechnique

    ReaMetrix oers customconjugation services inAntibody, proteins,Chemokines, micro andnanosphere conjugations with

    uorophores andQuantum dots

    ReaMetrix oers development

    of stable cell lines expressingprotein of interest at high,homogenous levels

    Detection of PCR Products onFlow Cytometry AssayQualitative Detection of PCRProducts on Flow Cytometry

    ReaMetrix can customize Antibody-Dye combinations to meet yourrequirements

    We provide a completedevelopment solution from, thecloning of novel genes into suitableexpression vectors, transfectionoptimization, stable clone isolation