R&D is the foundation for the competitiveness and ... · R&D is the foundation for the...

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R&D is the foundation for the competitiveness and stability of any university. It comprises about 50% of all activities conducted by a leading university. Universities do not only teach but also produce practical knowledge in sciences.

Voronezh State University is the alma mater of a Nobel Prize laureate, Pavel Alekseyevich Cherenkov. We take great pride in our graduates. Our researchers have very stable publication records in Web of Science and Scopus, and these are good records. VSU holds leading positions in various Russian and international university rankings. Thus, our university was included in the world leading rankings, such as the global QS World University Rankings, and Times Higher Education World University Rankings. People are aware of our university.

VSU's activities are also aimed at strengthening the innovative industries of the Russian economy. By offering support in this area the university has created a system of R&D advanced development and dynamic implementation of R&D projects. Commercialisation of our researchers’ inventions and projects has always been interconnected with the following question: “Did we manage to move forward and actually produce the devices, technologies, and equipment we are suggesting?” And the answer to this question is “Yes, we did.” The system for the commercialisation of our inventions and R&D projects is up and running. The chain “fundamental research — applied research — innovative project — introduction of the project into production” has been working quite efficiently. Following this chain we were able to implement a few large hi-tech production projects. In some cases R&D projects have given place to projects which involve research, development, design, and testing. Thanks to the efficiency and active approach of the researchers, in 2015 and 2016, VSU was recognised as "the best innovative university in the Voronezh Region". Our researchers are highly praised by the Ministry of Education and Science of the Russian Federation. In 2017, we won two large contests held by the Ministry. Our university is now officially the centre of innovative, technological, and social development of the Voronezh Region, and can now open a university-based engineering centre. VSU does its best to enhance the competitiveness of the region.

In this volume you will find all the information about the latest results and most advanced projects conducted by the scientists of Voronezh State University. It will provide you with the details of each project, its stages, results, cost, and profitability. It’s time to demonstrate our innovation potential! We are sure you’ll be amazed at how big it actually is!

VSU Rector, DSc in Economics,Professor D.A. Endovitsky

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PROJECTS CONDUCTED WITHIN THE FRAMEWORK OF THE DECREE OF THE RUSSIAN GOVERNMENT NO 218 "STATE SUPPORT OF DEVELOPMENT OF COOPERATION BETWEEN RUSSIAN EDUCATIONAL INSTITUTIONS OF HIGHER EDUCATION, STATE RESEARCH INSTITUTIONS AND ORGANISATIONS THAT IMPLEMENT INTEGRATED HI-TECH PRODUCTION PROJECTS AS A PART OF THE SUB-PROGRAMME "INSTITUTIONAL DEVELOPMENT OF THE RESEARCH SECTOR".Multifunctional high-speed video module with commercial linear sensors of near IR radiation ............................................ 6

Developing a hi-tech industry for plant oil and fibre processing and transformation into non-food products ................ 8

INFORMATION TECHNOLOGIES

Full-scale production of the rehabilitation system Breath&Play for children enduring pulmonary pathology ..............10

Information System with tactile and temperature feedback in myoelectric prostheses ......................................................... 12

Software for creating non-electronic interactive surfaces and gadgets. .........................................................................................14

Software package for increasing image and video resolution ............................................................................................................... 16

Universal automobile diagnostics and repairs suit CAR DIS .................................................................................................................... 18

An eye-tracking system capable of identifying the positioning of the pupil on a video image that can be used for various purposes ............................................................................................................................................................... 19

Development of an online platform for the analysis, forecasting, and optimisation of energy consumption ............... 20

MACHINE BUILDING

Fuel processing device Knyaz-1 ............................................................................................................................................................................ 21

Innovative technology of preliminary thermomechanical treatment aimed at hardening cutting and measuring tools ........................................................................................................................................................22

Advanced device for transportation of liquids through pipelines ....................................................................................................... 24

PHYSICS

Development and enhancement of nuclear physical and X-ray methods for nanomaterials diagnostics .................. 26

Creating an enterprise for implementing various methods of enhancing the resistance of Electronic Component Base to modern and future types of noise ................................................................................................28

Fibre optic device for early diagnostics of oral cavity pathology ........................................................................................................ 30

Magnetic nanostructured transition metals silicides with the optical magnetic reversal effect for silicon-based micro-and nanoelectronics ..................................................................................................................................................32

A unit for sol-gel synthesis of nano particles with size dependent optical properties ..............................................................34

Innovative development and implementation of a correlation receiver for ultra-wideband radioelectronic and location systems ..................................................................................................................................................................................................36

TABLE OF CONTENTS

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Energy-efficient technology of producing nanomaterials for power electronics ........................................................................38

Independent automated system “Smart Greenhouse” .............................................................................................................................39

CHEMISTRY

Creating hi-tech production of efficient multifunctional membrane units for high purity hydrogen evolution from hydrogen-containing gas mixtures ....................................................................................................................................40

Production line of ion-exchange membranes ................................................................................................................................................ 42

Full-time hi-tech production of innovative water-retaining supersorbent Solid Water ...........................................................44

Development of energy-saving technologies used in the process of production of emulsifiers and emulsifying systems for food and non-food industry based on raw materials and their derivative products ......................................................................................................................................................................................... 46

Development of new corrosion inhibitors for non-ferrous metals based on the functional derivatives of aminotriazole ........................................................................................................................................................................................................... 48

BIOTECHNOLOGIES

Molecular design and production of antibiotics and preservatives based on lytic bacteriophages and viruses ........... 49

Microbial production of hyaluronic acid for the cosmetic and pharmaceutical industries ...................................................... 50

Nutrient additives for livestock animals ........................................................................................................................................................... 51

Development of the technology of the common oak (Quercus robur L.) quickened growth for the reafforestation of the Central Black Earth Region .......................................................................................................................52

Development of the genetic identification method of biomaterials’ taxonomy, based on DNA barcoding .....................54

Development of biotechnologies for plant pollination and protection from pests and vermin in greenhouses ............56

Development of unique equipment and manufacture of consumable products for bumblebee farms and greenhouse facilities ..........................................................................................................................................................................................58

MRI contrast agent Lipocsan .................................................................................................................................................................................60

PHARMACEUTICS

Development of innovative encapsulated dosage forms based on microcapsules ......................................................................62

Development of an innovative technology for the generation of wound healing multi-enzymatic medication “ZAZHIVIN” ................................................................................................................................................................................................................... 64

Development of an innovative wound healing medicine “Rannet” .................................................................................................... 66

GEOLOGY

Development of Pavlovsk Mining and Concentration Complex screening processing technology aimed at enhancing the market demand for them and decreasing the environmental impact ........................................................... 68

Contacts ........................................................................................................................................................................................................................... 70

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VIDEO MODULE

The proposed video module registers moving objects line by line, converts received video data into digital format, processes the lines (frames) of the image using special algorithms and determines the output signals. The module includes an image receiver (a monochrome or an RGB sensor), a signal coder, and a digital signal processor. Analog output data is digitalized by the analog-to-digital converter (14 bit) and passes to a special signal processing processor – dual-core Analog Devices ADSP-BF561 Blackfin processor. Industrial interface of RS485 standard is used to connect the VM to a PC. Using this interface it is possible to develop industrial networks employing a large number of video modules. The output signals of the module are presented in the form of 4 digital differential pairs capable of delivering data transfer speed up to 30 MHz.The project was conducted within the framework of the Decree of the Russian Government No 218 dated 9 April 2010 "State support of development of cooperation

Project product(s) (commercialised object)High-speed video module based on commercial linear sensors of near IR radiation for various computer vision systems.

Enterprises that may be interested in the results of the projectThe owner and the major consumer of the proposed video modules is OOO Voronezhselmash.

Stage of progress

OOO Voronezhselmash together with a team of researchers from Voronezh State University (Research Institute for Physics and the Faculty of Computer Sciences) have designed a product line of colour sorting machines, including models that simultaneously analyse images from several video modules working in different spectral ranges.

between Russian educational institutions of higher education, state research institutions and organisations that implement integrated hi-tech production projects as a part of the sub-programme "Institutional development of the research sector" of the state programme of the Russian Federation "Science and technologies development for 2013-2020".

Multifunctional high-speed video module with commercial linear sensors of near IR radiation

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Advantages over existing analogues

Much lower price, precise adjustment mechanism for optimal positioning and tuning of the video modules, flexible and user-friendly software used to sort various objects.

Patent protection for the main technological solutions of the project

1. Patent 2367832, Russian Federation, IPC F16K 31/02 (2007.11) Fast switching solenoid valve / patent holders: G.V. Chuiko, V.D. Strygin, B.A. Zon, G.V. Pakhomov, A.A. Churikov, V.A. Shulgin; applicants and patent holders: G.V. Chuiko, V.D. Strygin, B.A. Zon, G.V. Pakhomov, A.A. Churikov, V.A. Shulgin; statement No. 26 published 20.05.2009.

2. Utility model patent, RU 83436 U1 Russian Federation, IPC B07C 5/342 (2006.01) Grain colour sorter apparatus / authors: G.V. Chuiko, V.D. Strygin, G.V. Pahomov, A.A. Chyurikov, V.A. Shulgin, A.A. Ageev, Ya.I. Shkirya; patent holder – OAO Voronezhselmash; published 10.06.2008, statement No. 16.

3. “Laser sorter machine” / authors: E.M. Babishov, V.A. Goldfarb, D.A. Minakov, G.V. Pahomov, V.D. Strygin, G.V.Chyuiko, A.A. Chyurikov, V.A. Shulgin; patent holder – OAO Voronezhselmash.

4. “Fibre optic laser sorter” / authors: E.M. Babishov, V.A. Goldfarb, D.A. Minakov, G.V. Pahomov, V.D. Strygin, G.V.Chyuiko, A.A. Chyurikov, V.A. Shulgin; patent holder – OAO Voronezhselmash.

Commercialisation risks

The project’s implementation may carry the following risks:• volatility of the currency market;• overrated market;• high requirements for employees’

qualifications;• lack of efficient maintenance services.

Project’s initiator (developer)

OOO Voronezhselmash, FSFEI HE VSU’s research team.

Total cost (funding) of the project in roubles160,000,000.

Source of fundingThe sources of funding are investments by OOO Voronezhselmash, national science foundations (“Skolkovo”, the Fund for Promotion of Small Enterprises in Scientific and Technical Field, grants from the Ministry of Education and Science, etc.), FSFEI HE VSU, as well as internal funds.

Duration of the project2017–2019.

Payback periodThe project is already generating profit.

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OILS PROCESSING

Project objectives: design and development of production technologies for new surface-active materials compositions based on natural raw material, including oil and fibre, and their processing waste in the framework of the construction of a fat-containing waste recycling plant.

Project product(s) (commercialised object)A wide range of high-performance emollients, foam boosters, and foam viscosity increasing agents based on plant oil and fibre, as well as emollient compositions, foam booster compositions, and viscosity compositions used in the cosmetic industry.


The competitiveness of the products is based on their lower production cost as compared to foreign and Russian analogues, due to the fact, that the enterprise uses its own raw materials (sunflower, soya-bean oil, and palm oils) and waste product from oil and fat production, as well as advanced production technologies.


At the moment the following risks are highly probable: fluctuations in price and currency exchange rate, manufacturing risks (equipment failure, various defects); Force Majeure.

Enterprises that may be interested in the results of the project

The prospective consumers of the proposed emollient compositions, foam booster compositions, and viscosity compositions are enterprises manufacturing hard and liquid soap, cosmetics, personal hygiene products, household chemicals and cleaners (liquid and powder), foam concrete blocks, etc.Following the programme for improving its environmental efficiency, OAO EFKO has set up its own hard soap and soap chip manufacture (both lye and toilet) where the proposed innovative additives are used. The capacity of the major production line is 6 tons per hour, i.e. 49 thousand tons in one year.

Developing a hi-tech industry for plant oil and fibre processing and transformation into non-food products

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As a result of the project, 5 invention patents of the Russian Federation were published, and 2 patent applications submitted.


The project was initiated by OAO EFKO of the EFKO Group.

Total cost (funding) of the project in roubles360,000,000

Source of funding50% (180 million roubles) – state funding, 50% (180 million roubles) – extra-budgetary financing – investment by the industrial partner.

Stage of progress

Production technologies were developed for the compositions of new surface-active materials based on natural raw material, including oil and fibre, and their processing waste in the framework of the construction of a fat-containing waste recycling plant.A technology was developed for producing emollient compositions based on natural materials – a mixture of plant acid esters (sunflower oil and soya-bean oil) and organic spirits, including linolic, olenic, and palmitic acid esters.A technology was developed for producing foam booster compositions based on natural materials – a mixture of amino and sulfo derivatives of plant oil fatty acid (sunflower oil and soya-bean oil), including mono– and diethanolamide, and sulfocationites of linolic, olenic, and palmitic acid esters.A technology was developed for producing viscosity compositions based on nanocrystalline cellulose produced from plant industry waste and sugar industry, including the dust of sugar beet pulp (fractions of less than 0.1 mm).

Duration of the project12.02.2013 – 31.12.2015

Payback period4 years

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Breath&Play

The system is a hardware-software system that registers breathing information and employs biofeedback in the form of a game. The system will help children recover from lung diseases and to restore lost functions. Doing breathing exercises in the form of a game keeps children interested in the rehabilitation process. It is also possible to save the results of each exercise session in the system’s database, and thus better control the process and assess the dynamics of the rehabilitation process. The system is based on a device developed by VSU’s researchers – a digital spirograph that can register the maximum expiratory flow rate, breathing rate, and lung capacity. The system includes PC software and a mobile Android application with game based breathing exercises, as well as a programme for analysing the dynamics of the lungs performance for each user.

Project product(s) (commercialised object)A digital spirograph that can register maximal expiratory flow rate, breathing rate, and lung capacity. PC software and a mobile Android application with game based breathing exercises, and a programme for analysing the dynamics of the lungs performance for each user. The product we propose is an information system consisting of the said device and software.

Stage of progress

A functioning prototype of the device and the software for game based breathing exercises were created.

Full-scale production of the rehabilitation system "Breath&Play" for children enduring pulmonary pathology

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• Size (fits into one’s palm, weights no more than 200 g).

• Connection to a tablet or a smartphone.• Game based exercises and rehabilitation.• Analysis of data used in medical

diagnostics methods (breathing rate, forced expiratory volume, etc.).

• Low production cost (about 1000 roubles).


Intellectual property rights for the software are registered for the computer programmes and database certificates• No. 2015661028 dated 15 October 2015,

and• No. 2016610682 dated 18 January 2016.• Patents on the digital spirograph and the

rehabilitation methodology are about to be published.

Enterprises that may be interested in the results of the project.

• hospitals;• rehabilitation centres;• sports clubs;• kindergartens;• schools.

Total cost (funding) of the project in roubles1,600,000 for the project itself, and 4,000,000 in order to introduce the product into the market.

Source of funding• venture

investment;• the Fund for

Promotion of Small Enterprises in Scientific and Technical Field;

• bank loans;• internal

financing.• The total funding

currently amounts to 500,000 roubles.

Duration of the project3 years



• Lack of demand. This kind of risk can be eliminated by establishing close contacts with prospective customers starting from the earliest stages of the product development.

• Funding risks. Can be eliminated by attracting investors, using bank loans, and internal financing.

• Problems with certification. Certification is required only for a limited number of the system’s functions concerning medical diagnostics, while most of its functions do not require any certification.

• Increase in competitiveness level on the market. Low production cost (about 1000 roubles) and a large number of functions allow the system to compete with existing analogues. Continuous upgrade of the device itself and the rehabilitation methodology used will help to maintain a stable position on the market.


Alexey Maximov,lecturer at the Faculty of Computer Sciences, VSU.

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Information system with tactile and temperature feedback in myoelectric prostheses

Tactile and temperature feed-back system

in prostheses

Project product(s) (commercialised object)Tactile feed-back system in myoelectric prostheses and the method of production. Temperature feed-back system in myoelectric prostheses and the method of production.

Stage of progressA laboratory machine employing the tactile feed-back system was produced.


Prospective customers are state and private healthcare services and hospitals, such as military rehabilitation centres, myoelectric prostheses manufacturers, as well as the disabled and their families.


The problem of artificial biological feed-back in the filed of prostheses is becoming more and more urgent. In the USA, the research of feed-back in myoelectric prostheses is financed by the Defence Advanced Research Projects Agency (DARPA).Among the organisations conducting their research in this field are the following:• laboratory of user-friendly bio-electric

interfaces at the Swiss Federal Institute of Technology in Lausanne (Switzerland);

• laboratory of advanced development in robotics and systems at the Scuola Normale Superiore di Pisa (Italy);

This is a system that expands the functionality of a myoelectric prosthesis either autonomous or with partial integration into artificial limbs. The system includes tactile and temperature sensors, a single-board computer, a USB-module, a tactile stimulator, and a tutorial on how to use the system.

• the University of Tel Aviv (Israel).There are also three large companies that are leaders on the market of myoelectric prostheses without artificial biological feedback (these companies sometimes use artificial biological feedback as an experiment or in exclusive models):• RSLSteeper;• I-LIMB;• Otto Bock.All the existing analogues have the same disadvantage – high price (starting with $ 20 000) and lack of feedback.There have appeared recently a number of projects in Russia that offer lower price, but still have no feedback systems.

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1. Engineering (presence of similar systems on the market; lack of equipment necessary to conduct a thorough research and develop the software; lack of volunteers and hence, no opportunity to test the system and create a unified testing database).

2. Intellectual (lack of facilities required for the research, such as laboratories, software, and volunteers; absence of project participants due to illness, a business trip, or for any other reason).

3. Investment (lack of financing).4. Marketing (lack of demand among the

prospective consumers; inability of the prospective consumers to purchase the product; prospective customers being unaware of the product).

Patent protection for the main technological solutions of the projectA patent application is being prepared for the “Feedback method for a myoelectric prosthesis”.

Total cost (funding) of the project in roubles

At least 5 000 000 roubles to set up a small-scale production line.

Source of fundingGrant received within the the framework of programme "Participant of the Youth Scientific and Innovation Competition (U.M.N.I.K.)” Additional funding is required in order to produce a prototype. Further funding will be required to launch a small-scale production.

Duration of the project2017–2020

Payback periodon the 4th year from the start of the production.


Laboratory of Medical Cybernetics at the Faculty of Computer Sciences.Supervisor: Ya. Turovsky, lecturer.Implemented by K. Fisenko, student.

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SmartWall-based non-electronic interactive surfaces and gadgets have no direct analogues. Among the indirect analogues of the product are any electronic gadgets or devices using sensing technologies (such as interactive boards) which are much more expensive and fragile.


• Innovation risks. • Financial risks. • Market risks. • Business risks.

SmartWall

The aim of the project is to develop the SmartWall software based on a new method for the segmentation of noisy images with dynamic threshold values for image binarisation. The software makes it possible to control a computer using non-electronic surfaces such as walls, paper, or a table surface. The software uses computer vision techniques to transform any surface into an interactive element without sensing technologies. The SmartWall software was developed in Visual Studio 2013 using C# programming language. .NET Framework 4.5 is required. SmartWall-based applications run on the Microsoft Windows OS and require a webcam. SmartWall can create two types of interactive surfaces - stationary and portable. The software can be applied to surfaces of any colour and texture and in various light level. It can also work with projection screens.

Project product(s) (commercialised object)SmartWall Software and SmartWall-based applications and services that can be used in various spheres.

Software for creating non-electronic interactive surfaces and gadgets.

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An application for the computer programmes and database certificate has been submitted.


Mechislav Prinev,student of the Faculty of Applied Mathe-matics, Informatics, and Mechanics, VSU.


The main potential customers are educational institutions, rehabilitation centres, shopping centres, agricultural enterprises, and individuals.

Total cost (funding) of the project in roubles.5,000,000.

Sources of fundingIt is planned to use the income from the sale of the software, and to obtain additional financing by participating in grant competitions, such as U.M.N.I.K. and Innovation Cup. In 2018, it is also planned to submit an application to the Start programme of the Fund for Promotion of Innovations, and obtain financing from the regional budget.

Stage of progress

The SmartWall software has been developed as well as the following SmartWall-based products:• a programme that can binarise and save

noisy images either downloaded, or captured by the webcam;

• a programme that allows to control an audio player using a paper remote controller;

• a concept version of the programme for controlling a computer with one’s eyes;

• SmartWallBand application (allows to control Skype using buttons drawn on a textile bracelet);

• SmartWallBattle application (requires a projector and a webcam; can be used in interactive quizzes organised by educational institutions. Players touch drawn buttons and the application registers the time of the answer, decides, whether it is correct, and keeps track of the team points);

• a concept version of the programme for sensory rooms. The programme performs segmentation of images from multiple cameras and on various surfaces;

• entertainment and educational content for small children and children with disabilities.

Duration of the project3 years.

Payback time4th year of active sales.

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INCREASED IMAGE QUALITY

Various systems are now being developed in order to register and process optical information. The effectiveness of such systems depend on the quality of the analysed data which is often presented in digital image and video formats. One of the major requirements to the quality of such images is that they must have high resolution (even the smallest details, such as text or faces, should be recognisable). This requirement is often very difficult to fulfil due to physical and technical limitations of the equipment used. Another requirement is that any noise appearing after image registration or during its transfer by any communication channel, should be compensated for. Such noise can be either additive, or applicative (registered images may get corrupted with impulse noise, overlapping areas, etc.).The proposed software employs new algorithms for increasing the resolution that improve the quality of the images and eliminate the effect of both additive and applicative noise (overlapping areas, flares, impulse noise, etc.).

Project product(s) (commercialised object)The project’s product is a PC application that can increase the resolution (size and detail quality) of several images (or frames) and improve their quality. One of the project’s objective is also to develop mobile applications with the same functions.

Stage of progress

Key algorithms were developed in MATLAB. A prototype of the PC software for image sequence processing was developed. The software is being developed using C# and C++.The results of the project were presented in 12 papers, including 4 papers published in journals included in the list of referenced scholarly journals recommended by the State Commission for Academic Degrees and Titles. A PhD thesis on the topic was successfully defended. The results were also reported at six international conferences.

Software package for increasing image and video resolution


Payback periodApproximately 2 years.

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The major advantage of the proposed software is that it employs new unique algorithms for image processing that help to increase the resolution and eliminate the effects of noise and distortions such as objects overlap, or clouds on air-photography images. It is also possible to perform image processing employing parallel processing with automated adjustment of the algorithm.


An application for the computer programmes and database certificate has been submitted to the Federal Institute of Industrial Property.A GOST Р15.011-96 report and a patent pattern GOST 15.012-84 are to be prepared.


Alexander Ivankov,lecturer at the Department of Information Security and Processing Technologies of the Faculty of Computer Sciences.

Enterprises that may be interested in the results of the project.

The project is of great interest to companies specialising in surveillance systems used for traffic control. Terms of partnership are now being discussed. The research is already being conducted in collaboration with some of the interested companies.Individuals may also be among the prospective consumers of the product. A number of polls demonstrated that they would also like to purchase such software to install on their PCs.

Total cost (funding) of the project in roubles7,000,000. The major expenditures include the developers’ salary and organisation of promotion events.

Source of fundingAmong the prospective sources of funding are the Skolkovo Foundation, State Foundation for Assistance to the Voronezh Region Small Innovative Enterprises, Foundation for Developing Internet Initiatives, Russian Venture Company Foundation, inner financing, a VSU-based small innovative business, and grants from the Fund for Promotion of Small Enterprises in Scientific and Technical Field awarded to the participants of such programmes as U.M.N.I.K. and START. Another possible source is bank loans.


• Lack of financing (15%). Proposed solution – bank loan.

• Failure to meet deadlines (30%). Proposed solution – it is advisable to divide the project in a number of small stages and report to the client upon completion of each step.

• New requirements (40%). Proposed solution – it is advisable to plan and discuss with the client all the required functions and project deadlines in between the project’s stages.

• Underestimating other products. New competitors on the market (50%). Proposed solution – specialisation in one field (video only or image only); adjustment of pricing policy.

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Universal automobile diagnostics and repairs suit CAR DIS

CAR DIS

Project product(s) (commercialised object)CAR DIS device, interactive software, and a unique database containing information about practically any kind of motor vehicle, including lorries and special vehicles.

Stage of progressA CAR DIS prototype was produced that performs all the functions (diagnostics, programming, and coding) via the K-line protocol.


The risks are reduced to the minimal level thanks to collaboration with industrial partners who actually perform automobile diagnostics, maintenance and repair, as well as revision of marketing strategies, diversification of the sources of financing, and high quality of the product.


The results of the project will be interesting to car services, authorized dealers, auto parts stores, and drivers. The project will also be interesting to enterprises specialising in electronic parts and units used to construct the device.


Maxim Glazykin, student of the Faculty of Applied Mathematics, Informatics, and Mechanics.


We have searched the database of the Federal service for intellectual property for patents about similar devices. As a result, we found no patents registered for devices with similar properties or functions as the proposed universal automobile diagnostics and repairs suit CAR DIS. A utility model patent application is now being prepared. It is due to be submitted in Spring 2017.


We examined 18 devices of various brands, including the Russian ones. None of these devices are capable of performing all the functions that CAR DIS will have. The analogues examined also have the following drawbacks: poor quality translations, unfriendly interfaces, improper assembly, unavailability on the open market, etc.

Total cost (funding) of the project in roubles

12 500 000

Source of fundingProspective sources of funding include inner financing, investment by Avtosvet chain, the Innovation Cup grant, subsidies for small innovative businesses (the Decree of the Voronezh Region Government No.817 dated 20 September 2013), the Fund for Promotion of Innovations (START and BUSINESS-START programmes), Skolkovo Foundation, the Foundaion for Business Development in the Voronezh Region.


Payback period2 years.

The aim of the project is to develop and produce an interactive device for the diagnostics, maintenance, and repair of practically any modern car, the likes of which will have no analogues in Russia.

years

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An eye-tracking system capable of identifying the positioning of the pupil on a video that can be used for various purposes

GLAZODVIG

Project product(s) (commercialised object)1. A device for

production of images of the eye area.

2. Software for marketing research.

3. Software for eye-operating systems for various devices.

4. Software for integration with augmented reality systems.

Stage of progressA prototype was produced. The software is under revision.


• Lack of demand – the risk level is very low as the results of the project can be applied in various areas.

• Lack of funding – the risk level is low as the project is in its final stage.


• Market research companies.• Rehabilitation centres and institutions

for critically ill patients.• Companies specialising in computer

peripherals.• Research laboratories.


Laboratory of Medical Cybernetics at the Faculty of Computer Sciences.Supervisor: Ya. Turovsky, lecturer.Implemented by A. Alexeiev, student.


5 computer programmes and database certificates were obtained. A utility model patent application is about to be submitted.


1. Lower equipment and software costs with comparable quality.2. Simpler software and equipment tuning process as compared to the existing analogues.3. The software can be used in other systems.4. The software can be used with any equipment that meets key requirements, without quality loss.

Total cost (funding) of the project in roubles450 000.

Source of fundingGrant received within the framework of the U.M.N.I.K. Programme – 400 000 roubles.First place at VSU’s innovation projects competition 2015 – 20 000 roubles.Private finances – 30 000 roubles.



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An online platform for the analysis, forecasting and optimisation of energy consumption with additional web-based applications for enterprises of national economy of the Russian Federation and house management companies. The platform will automatically keep track of energy consumption, as well as perform its forecasting and optimisation. It will also notify the consumers about their energy consumption levels. The architecture of the information and analysis system can be easily modified. The platform is user-friendly. Its services allow consumers to reduce operational costs and provide them with a substantial saving (up to 20%) of the cost of energy consumption.

Project product(s) (commercialised object)

A web-service allowing enterprises to save on the consumption and cost of electricity and other resources.


Cross-platform software and unique functions within one service. High availability of the platform - users can register themselves and quickly test the service. The system of collection, storage, and processing of data is organised in such a way that over 100,000 users can access the database of the platform at the same time.

Patent protection for main technological solutions of the project

The results of intellectual activity are protected as commercial secrets (know-how). The suggested method was assessed and estimated, and the know-how is officially now owned by Voronezh State University. Further steps to protect intellectual property rights are to be taken - applications for computer programs and data bases certificates are being prepared.

Enterprises that may be interested in the results of the projectEnterprises consuming from 100 kVA to 670 kVA with average electricity bills over 200,000 roubles per month. Enterprises with maximum capacity over 670 kVA purchasing electricity at retail price.

Total cost (funding) of the project in roubles.

First stage (operational tests) – 2,000,000. Further development and promotion of the platform – 5,000,000.

Sources of fundingFirst, the project was funded by VSU only. The project is currently being funded by a grant obtained within the Start-1 programme of the Foundation for Assistance to Small Innovative Enterprises in Science and Technology. It is planned that the project will be further financed from its own earnings as well as by funding from other sources.

Stage of progressBy the end of 2017 the project was 70% ready. Operational test of the beta-version of the platform are due to begin in the 2nd quarter of 2018.

Development of an online platform for the analysis, forecasting, and optimisation of energy consumption


Payback time1.5-2 years.


There are the following commercialisation risks: research and technical risks, production risks, market risks, financial risks, and human resources risks. Project’s initiator

(developer)

Alexander Kashirin;Faculty of Computer Sciences, VSU.

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Fuel processing device Knyaz-1


• The product may cease to be unique. • The device failure risk. • Unexpected suspension of production.


Transport enterprises and other companies using power units with combustion engines.


German Komarov,master’s degree student of the Faculty of Geology, VSU.


Patent No. RF172392. The details of the device construction will be protected as commercial secrets (know-how) without any information available about its functioning. The project was selected for the final of the OPEN INNOVATIONS STARTUP TOUR in Kursk.


High environmental performance, no need to interfere with the engine.

Total cost (funding) of the project in roubles.11,000,000.

Sources of fundingStart programme and VTB 24 lease payments.


Payback time3 years.

Development of a fuel processing device for• the purification of fuel from decaying

products and metal-based additives which clog fuel injection equipment in vehicles of Euro 3 - Euro 6 standards;

• the device also generates a hydrogen additive to improve fuel emissions, power output, and economy.


A device that generates a hydrogen additive without water, within the fuel itself. It does not require maintenance, and does not interfere with the work of the engine.

Stage of progressA prototype of the device was produced. A grant application within the Start-1 programme was submitted and is currently under consideration.

KNYAZ-1

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RESISTANCE ENHANCING

Innovative technology of preliminary plastic form-based thermomechanical treatment that allows increasing cutting and measuring tools resistance more than two times.

Project product(s) (commercialised object)Innovative technology of preliminary thermomechanical treatment aimed at hardening cutting and measuring tools.


The project develops mass-production technologies for preliminary thermomechanical treatment of instrument steel work pieces aimed at hardening cutting and measuring tools, i.e. increasing their depreciation period. These technologies allow decreasing tooling backup costs of machine workshops at machine engineering companies and decreasing companies’ losses caused by the necessity to replace/repair tools. Direct analogies, i.e. organisations that introduce tool hardening technologies based on innovative preliminary thermomechanical treatment techniques, were not found. Preliminary marketing analysis revealed several companies that offer tool hardening by means of surface hardening by coating.

Innovative technology of preliminary thermomechanical treatment aimed at hardening cutting and measuring tools

Key advantages over analogues:1) Low production cost.2) High fabricability (only one simple operation is added to the existing tool production technologies used at enterprises, i.e. work piece displacement upsetting when cold or hot.3) Tool lots do not need to be transported to be processed, and as a result to be stored, packaged, etc., as the enterprise’s equipment can be used for the innovative preliminary thermomechanical treatment (if pressure equipment is available).4) Surface hardening by means of coating can complement the innovative preliminary thermomechanical treatment (as instrumental steel microstructure is changed).


After the completion of the R&D works (2017) the obtained results of intellectual activity will be protected by an invention patent and a utility model patent issued by the Federal Institute of Industrial Property (Rospatent).


The key customers are professional consumers, i.e. large machine engineering plants with cutting and measuring tools workshops; small and medium-sized businesses producing specialised tools for machine engineering companies; and toolmakers with a large-scale production of standard cutting tools.


Source of fundingThe Foundation for Assistance to Small Innovative Enterprises in Science and Technology, industrial partner financing, and internal funds.

Stage of progress

A small innovation business – OOO I-Expert Group – was founded to commercialize the project’s results. The project is at the R&D stage.




Commercialisation risks connected with low innovative activity of enterprises’ management.


Alexander Khvan,Director of the VSU innovative business incubator of Voronezh State University, DSc in Technical Sciences, associate professor.

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TRANSPORTATION OF LIQUIDS

An advanced device for transportation of liquids through pipelines was developed. It is a new hydraulic electric pump with increased performance due to increased efficiency coefficient (approximately 20%) and improved ergonomics. It is also more reliable and has a longer life time owing to its simplified construction. All the above mentioned characteristics provide for a considerably lower cost of the product. The device is supposed to be used in oil and oil products transportation to create turbulent flows in the pipe line and as a result 3-4 times faster stripping of a tank car compared to the existing technologies.

Project product(s) (commercialised object)Advanced device for transportation of liquids through pipelines.


The developed innovative device for transportation of liquids through pipelines used for stripping of oil tank cars at oil tank farms has the following technological and operational advantages over the most advanced analogues with comparable performance and pipeline diameters.1) The cost of the device is 4-7 times lower than of the comparable analogues which

Advanced device for the transportation of liquids through pipelines

allows the potential consumer – oil tank farms – to decrease their investment into modernisation of the drainage system and to save on tank cars demurrage charges.2) Power consumption is 3-5 times lower than in the case of analogues which allows oil tank farms to save on energy.3) Lower weight and size of the device make it more mobile, interchangeable, and substitutable when used for stripping of oil tank cars, and also allows decreasing mounting costs of a new system in case of the oil tank farm modernisation.


An application for an invention patent was submitted to the Federal Institute of Industrial Property (Rospatent).


Potential consumers of new devices for faster stripping are oil tank farms and oil products supply enterprises.


Source of fundingThe Foundation for Assistance to Small Innovative Enterprises in Science and Technology, industrial partner financing, and internal funds.

Stage of progress

Pre-seed stage. R&D is conducted. A laboratory model was produced.




Commercial (market) risks – there is a possibility of failure to find expected demand for the device, i.e. consumers will not buy sufficient number of new devices. These risks can be offset by recruitment of qualified sales personnel and by investment into advertising and promotion of the product.


Alexander Khvan,Director of the VSU innovative business incubator of Voronezh State University, DSc in Technical Sciences, associate professor.

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Various nanostructures, including silicon-based, are of considerable scientific interest as owing to their special physical properties they can be used in the most advanced areas of science and technology, for example nanoelectronics, optoelectronics, spintronics, and etc. The main mechanisms and peculiarities of electronic energy spectrum and other physical properties in the process of transfer from high-volume crystalline materials to nanosized objects is poorly studied. Certain characteristics of interphase, interlayer and other structural interactions in nanostructured silicon-based systems, is also poorly studied in relation to optimization and stabilization of their advantageous properties. On the other hand, the fundamental science has formidable analytical methods to obtain detailed and highly precise information about electron energy structure of promising objects and nanostructures, including hybrids. Among such methods are nuclear physical and X-ray methods of nano materials diagnostics.

Project product(s) (commercialised object)Nuclear physical and X-ray diagnostic methods for nanomaterials.

Patent protection for the main technological solutions of the project2 applications for invention patents of the Russian Federation were submitted.

Development and enhancement of nanomaterials nuclear physical and X-ray diagnostic methods

Parameter stability of materials used in semiconductor and IC equipment influences significantly their performance and reliability. This influences the development of various devices, optimization of production conditions and their production as a whole. For example, silicon oxide and nitride, which are used for passivation of high voltage devices, have a number of disadvantages: electron and ion charges accumulated in the passivation layer influence the space charge region, there are immobile positive charges in the silicon oxide layer in the contact area with Si-wafer that causes crystal parameter instability and a decrease in the percentage yield. Today, constant increase in product standards leads to a constantly increasing demand in new technologies and new research methods for function materials. Hence, the existing analytical methods used in production do not allow fully studying the structure, phase and quantitative composition of the functional layers used in the production of semiconductor equipment.

NANOMATERIALS DIAGNOSTICS


Scientific and technological potential, detailed study of the fundamental basis of the developed diagnostic techniques.


The developed technologies can be demanded by Russian semiconductor production companies: OAO Angstrem, FGUP Pulsar, OAO NIIME and Micron, and ZAO Group of Companies El. For example, ZAO VFSD Micron needs technologies used to generate stabilized coatings for passivation of high voltage devices. The enterprise has technological capabilities for the formation of layers of a number of dielectric coatings: thermal silicon dioxide SiO2, low-temperature SiO2 (НТ SiO2), medium temperature SiO2 (СТ SiO2), medium temperature phosphosilicate glass, silicon nitride Si3N4, silicon oxynitride, polyimide, and polycrystalline silicon. One of the particular features of the production of semiconductor equipment is high integrity and stability of materials’ parameters.Among other potential consumers of the project’s results can be steel industry companies (where high precision element, phase, and structural analysis are needed).


Source of funding15,430,000 roubles – of federal financing.5,400,000 roubles – industrial partner financing.

Stage of progress

The following diagnostic techniques were developed:• Ultrasoft X-ray spectroscopy

diagnostics of electronic structure and phase composition of thin-film silicone-based nanostructures;

• Diagnostics of non-destructive phase analysis of surface and subsurface layer of experimental samples of thin-film silicone-based nanostructures;

• Moessbauer spectroscopy-based diagnostics of hybrid biological nanoobjects (Dps proteins).

Duration of the projectStarted on 11 August 2014Finished on 31 December 2016.



• Decrease in investment programmes by potential consumers as a result of financial instability.

• Technological unavailability of the enterprise.

• Uncertainty with regard to the expected investment income

Project’s initiator (developer)Evelina Domashevskaya, Head of the Department of Solid-State Physics and Nanostructure of Voronezh State University, DSc in Physics and Mathematics, professor.

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The Department of Electronics of Voronezh State University has very deeply rooted traditions, a long-standing experience in the area of electromagnetic compatibility, and a highly qualified scientific school headed by Professor A.M. Bobreshov (Dean of the Faculty of Physics, Head of the Department of Electronics). For the last 10 years, its staff has been conducting intense research of ultra-wideband and narrowband radio systems cofunctioning. For example, evaluation methods of ultra-wideband interference on the element base were developed; research was conducted and attempts to explain physical mechanisms of the interference effect were made. Major differences between traditional harmonic noise and ultra-wideband interference were determined. Parameters which consider the physical nature of the effect and which can be used to evaluate the functioning of devices in the ultra-wideband interference environment were determined. Recommendations were made about the performance optimization of radio systems aimed at improving their functionality when exposed to interferences of various types.A solution was found for the fundamental and applied problems of resistant functioning of the electronic components in the ultra-

Creating an enterprise for implementing various methods of enhancing the resistance of Electronic Component Base to modern and future types of noise

INTERFERENCE ELIMINATION

Project product(s) (commercialised object)Automated measurement systems.

Stage of progressThe impact of impulse overloads on the electronic components was studied. Reversible failures were revealed and experimentally studied. Works were conducted in cooperation with the Ministry of Defence of the Russian Federation.

wideband interference environment as a result of creating automated measurement systems in the radioelectronic companies.Earlier projects were used to develop a method to assess resistance capacity of the electronic components of the electronic equipment to discontinuous ultra-wideband interference. Impulse signals are extremely penetrating and can be dangerous for modern communication systems.


• Automated measurements that can be introduced into a specified production and that will take into account particular features of the production and its products.

• Specified parameters for assessment of electromagnetic compatibility of electronic components base and electronic elements.

• Possibilities to detect ways to improve process and design parameters of semiconductor devices and electronic elements.


1. A.М. Bobreshov AIK EMS 3.6.2: Certificate 2013611752 / Voronezh State University; А. М. Bobreshov, I.S. Korovchenko, V.A. Stepkin, G.K. Uskov. – 2013. (№ 2012660891; submitted 11.12.2012; published 20.03.2013).

2. A.М. Bobreshov Test module for assessing the resistance capacity of the semiconductor electronic components of the low-noise microwave band amplifier to high amplitude impulse noise: patent 134667 Russian Federation: MPK G01R31/26 / А.М. Bobreshov, I. S. Korovchenko, V.A. Stepkin, G. K. Uskov; author and patent holder: FSFEI HPE VSU – № 2013136406; submitted 05.08.2013; published 20.11.2013. – 13 p.


Igor Korovchenko,PhD in Physics and Mathematics, associate professor at the Department of Electronics of the Faculty of Physics of Voronezh State University.


• Work complexity can be under-estimated and as a result the project can fail to be fully implemented.

• During the production stage, there is a possibility of disruption in the supply of components and as a result the suspension of production and the disruption of production and sales plans.

• Some necessary components can be taken out of production.

• Underrated or overrated sales market.


Source of fundingStrategic production partner is AO Concern Sozvezdie. It is planned to obtain financing from the Foundation for Assistance to Small Innovative Enterprises in Science and Technology, the Skolkovo Foundation, and other sources.

Payback period3.5 years

Duration of the project2016 – 2018


Today, there are about 5–6 companies in Russia which are involved in the introduction of automated solutions and specialise in microelectronics. The estimated market volume is 200–250 million roubles for automated control systems and about 50 million roubles annually for the maintenance. Moreover, there has been a tendency for increasing production output, purchasing of new production lines, and opening of new productions.

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Fibre optic device for early diagnostics of oral cavity pathology

in vivo

Today, one of challenges in dentistry is early non-invasive diagnostics of the most common tooth pathologies in vivo, i.e. caries, non-carious diseases i.e. wedge-shaped defects, erosion, pathological abrasion of dental hard tissues, etc., dental disorders that started before tooth crowning, such as: fluorosis, retrognathia, epulis, etc., and other pathologies of oral mucosa: lichen acuminatus, leukokeratosis, and etc. The project is aimed at the development of a device for early non-invasive express diagnostics of the above mentioned mouth cavity pathologies in vivo by means of spectrum analysis instruments: laser-induced fluorescence and reflectance spectroscopy. Additionally, the device can be used to control treatment, photodynamic therapy, photopolymerization, and dental bleaching. The key advantages of the device are its mulifunctionality, reliability, and precision.

Project product(s) (commercialised object)A device for early non-invasive express diagnostics of mouth cavity pathologies in vivo by means of spectrum analysis instruments: laser-induced fluorescence and reflectance spectroscopy. Additionally, the device can be used to control treatment, photodynamic therapy, photopolymerization, and dental bleaching.


The device which is most similar to the proposed device in terms of functionality and specifications is DIAGNOdent pen 2190, KaVo (Germany). Nevertheless, this device is, firstly, more expensive, and, secondly, can only be used to treat carious pathologies. DIAGNOdent pen 2190 cannot be used for treatment control and non-carious pathology diagnostics.


Patented optical circuit proved to be efficient to record a very low dental tissue and oral mucosa fluorescence signal [Patent of the Russian Federation № 2011119146].It is also planned to prepare and to submit the following applications for inventions:• Non-invasive non-carious pathology

diagnostics device.• Non-invasive oral mucosa pathology

diagnostics device.

Total cost (funding) of the project in roublesExtra-budgetary investments and internal funding will amount to 6 million roubles within a 3 year period of the project's implementation.Budgetary investments will amount to 14 million roubles within a 3 year period of the project's implementation.

Source of fundingNational foundations (Skolkovo, the Fund for Promotion of Small Enterprises in Scientific and Technical Field, grants from the Ministry of Education and Science, etc.), investment from private companies, FSFEI HE VSU’s investments, and internal funds.


Payback period4–5 years


Dmitry Minakov,PhD in Physics and Mathematics, associate professor, researcher at the Fundamental Department of the Faculty of Physics of Voronezh State University.

Iraida Sarycheva,PhD in Medical Sciences, deputy chief doctor at Burdenko Voronezh State Medical University’s dental clinic.

Stage of progress

• A method used to record dental tissue and oral mucosa fluorescence spectrum and diffuse reflection was developed. Algorithms to process recorded spectrum data were developed.

• A device prototype used to excite and record fluorescence spectrum and record dental tissue and oral mucosa spectrum reflection was developed.

• Dental tissue, both intact and invaded by various pathologies, were studied by means of optical spectroscopy, raster electron microscopy, and XRD microscopy methods. The results obtained prove that laser-induced fluorescence can be used for early non-invasive diagnostics in vivo of various pathologies of the human oral mucosa. For the first time, it was proved that laser-induced fluorescence can be used to diagnose early stages of wedge-shaped defects, erosion, fluorosis, and epulis.


Market sectors:• Geographical: the Russian Federation,

Kazakhstan and others, EU countries, South East Asia, the USA, etc.

• Product: restorative dentistry and cosmetology.

Potential customers:• Dental clinics (there are about 80,000

restorative general practitioners in the Russian Federation [DISCOVERY Research Group]): MVK Beauty Line, Dentaljaz, StomArtStudio Leonardo, Dental Mir, ORTODONT.PRO, Interdent, Virtuos, Dental City, Kolobri, TARI-DENT, Dentika, and etc.

• Cosmetological institutions: Bikord, Art-klinik, Beauty Trend, LINklinik, Best klinik na Krasnoselskoi, and etc.


• Volatility of the currency market and as a result increasing prices for optics, fibre optics, spectrum equipment, and electronics.

• Overrated sales market.

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NANOSTRUCTURED TRANSITION METALS SILICIDES

The goal of the project is to create magnetic nanostructured transition metals silicides for super-dense data recording by means of an optical method, i.e. circularly polarized light.The obtained structures are suggested to be used for high response non-volatile memory devices using super-dense data recording.The production of magnetic nanostructured transition metals silicides with magnetic response at room temperature will allow integrating silicon-based microelectronics into spintronics.The developed approaches to the synthesis and modelling of magnetic nanostructures which are based on the latest global achievements and VSU’s own developments will provide the top performance.Development of near-field optical probes will provide for a considerable increase in density of data recording/reading in magnetic nanostructured transition metals silicide systems.The developed technologies, equipment, and devices will expand nanotechnology production capacities and will be demanded in such areas of science and technology as micro– and nano– electronics, micro– and nano– system equipment, near-field optical microscopy, and integrated photonics.

Project product(s) (commercialised object)Magnetic nanostructured transition metals silicides with the optical magnetic reversal effect for silicon-based micro-and nanoelectronics.


• Low production cost of nanostructures formation.

• Single-domain magnetization of nanostructures;

• Optical magnetic reversal effect;• Compatibility with CMOS technology.

Stage of progressThe project is currently at the R&D stage aimed at the introduction of the product into production. The developed project surpasses the world’s scientific and technical level.

Magnetic nanostructured transition metals silicides with the optical magnetic reversal effect for silicon-based micro-and nanoelectronics

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• “A device for production of ferromagnetic silicon-based silicide nanoclusters”, № 102007 of 17.08.2010;

• “Production process of nanostructured layers of magnetic materials” № 074942 of 02.11.2012;

• “A method for information record and reproduction” № 059948 of 29.08.2012.


• Centre for on-chip-system engineering;• ZAO Micron, Voronezh;• Ecole Central de Lille, IEMN-Lille (the

Institute of Electronics, Microelectronics and Nanotechnology), France, Lille;

• Research institutions that specialise on the development and production in the area of spintronics, photonics, microelectronics, and microsystem engineering.

• NPK Technological centre, National Research University of Electronic Technology;

• Enterprises within the Innovation Technological centre of Saint Petersburg Electrotechnical University (LETI);

• OOO INTERTEKH;• OOO Analysis systems;• Technological centre for 3D chip

assembly;• OOO Zelnas;• Enterprises that specialise on research

measurement equipment and test objects;

• Introduction to academic programmes at universities.


Source of fundingGrants, subsidies, internal funds attracted funding.


Payback period3 to 5 years


• Environmental risks.• Marketing risks.• Technical risks.• Legal risks.• Commercial risks.• Financial risks, including inflation,

deflation, currency exchange rate fluctuations.


OOO Optoferronanocilitsid, science adviser – Alexander Lazarev, PhD, associate professor at the Department of Experimental Physics of the Faculty of Physics of Voronezh State University.

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SYNTHESIS OF NANO PARTICLES

This project is aimed at developing a technology and a unit for the synthesis of nano particles with size dependable optical properties. A unit for sol-gel synthesis of Ag2S, CdS, CdS/ZnS, ZnxCd1-xS colloid quantum dots and their hybrid associates with molecules of organic dyes was developed. The technology enables: 1) to generate hydrophilic gelatinized colloid solution with hybrid associates; 2) at the synthesis stage, to control size dependable optical properties of quantum dots to achieve optimal spectral matching of properties of associate’s components and to achieve maximum values for singlet oxygen photosensibilization.

Project product(s) (commercialised object)The proposed unit for sol-gel synthesis of nano particles with size dependable optical properties is designed to generate colloidal nanoparticles which can become an effective base for a new generation of products and technologies used to diagnose and treat ontological diseases.


• Photostability of generated hybrid associates alongside with sufficient efficiency of singlet oxygen photosensibilization.

• Initial hydrophilic properties of the produced colloid solution with hybrid associates.

• Low cytotoxicity.• Biocompatibility.• Low production cost.• Possibility to use normalized elements

and parts simultaneously used to solve other tasks.

Stage of progress

A prototype of the unit for sol-gel synthesis of nano particles with size dependable optical properties was created at the Department of Optics and Spectroscopy of

A unit for sol-gel synthesis of nano particles with size dependable optical properties

the Faculty of Physics of Voronezh State University, and a utility model patent of the Russian Federation was received. Moreover, synthesis methods of colloidal nanoparticles, CdS, CdS/ZnS, ZnxCd1-xS, and their hybrid associates with organic molecules of thiazine dyes were developed; a number of patents were received for these methods.

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• Utility model patent 134445, the Russian Federation, MPK B 01 J 13/00, B 82 B 3/00, B 82Y 40/00, A unit for synthesis of colloidal semiconductor nanocrystals by means of a low-temperature sol-gel method / O.V. Ovchinnikov, M.S. Smirnov, B.I. Shapiro, T.S. Shatskikh, A.S. Perepelitsa; author and patent holder: Voronezh State University (FSFEI HPE VSU) (RU). – № 2013127444/05; submitted 17.06.13; published 20.11.13, statement № 32. – 2 p.

• Invention patent № 2538262, the Russian Federation, MPK C 01G 5/00, B 01 J 13/00, C 09 K 11/02, Production process of semiconductor Ag2S colloid quantum dots / O.V. Ovchinnikov, M.S. Smirnov, B.I. Shapiro, T.S. Shatskikh, A.S. Perepelitsa, V.Y. Khokhlov; author and patent holder: Voronezh State University (FSFEI HPE VSU) (RU). – № 2013127476/05(040933); submitted 17.06.13; published 10/01/2015, statement № 1. – 9 p.

• Invention patent № 2540385, the Russian Federation, MPK C09K 11/54, C09K 11/56, B82B 3/00, B82Y 40/00, Production process of semiconductor cadmium sulphide colloid quantum dots / O.V. Ovchinnikov, M.S. Smirnov, B.I. Shapiro, T.S. Shatskikh, A.S. Perepelitsa, A.O. Dedikova; author and patent holder: Voronezh State University (FSFEI HPE VSU) (RU). – № 2013127477/05; submitted 17.06.13; published 10/02/2015, statement № 4. – 12 p.


Pharmacological companies, ontological centres, and OOO Science and Technology experimental centre “Nanotekh-Dubna”.


Source of fundingThe prototype was created with the support of the Russian Foundation for Basic Research, the federal target programme and the grant by the Ministry of Education and Science of the Russian Federation in the framework of the state order to higher education institutions in the sphere of scientific research for years 2014 – 2016.To conduct further commercialisation of the project it is expected to attract private investment and the investment of the venture capital fund OOO Maxwell Biotech Group.


Payback period7.7 years


Technical risks:• Absence of the required parameters

of colloidal nanoparticles ensembles produced by the proposed unit.

Medical risks:• Introduction of biomarkers will cause a

strong autoimmune response.Commercial risks:• The technology might fail to be listed

in the register of methods of high-technology medical care.


A team from the Department of Optics and Spectroscopy of the Faculty of Physics, Head researcher – Oleg Ovchinnikov, Head of the Department of Optics and Spectroscopy of the Faculty of Physics, DSc in Physics and Mathematics, professor.

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Energy-efficient technology of producing nanomaterials for power electronics

COLD SYNTHESIS OF SILICON-CARBIDE

Today, owing to its unique properties, silicon carbide (SiC) is used for various electronic equipment. Silicon carbide has the edge over the classical semiconductor materials – silicon (Si) and gallium arsenide(GaAs) for all important criteria.Silicon carbide is generated at high temperatures between 1,600 and 2,500 °С. As a result, it involves great energy costs and requires expensive equipment.The project proposes a whole new energy-efficient way of silicon carbide production at room temperature which also offers an import substitution solution.

Project product(s) (commercialised object)Technology of cold (23 °С) synthesis of silicon carbide crystal nanophase.

Duration of the projectThe implementation of the project is expected between 2017 and 2020.



The closest analogue of the proposed technology is sol-gel technology developed by a research team from Ulyanov Saint Petersburg State Electrotechnical University "LETI". The proposed method is used to generate silicon carbide at 700 °С, compared to the classical technology that uses temperature between 1,600 and 2,500 °С.The innovative project proposes a unique technology that allows decreasing production costs and generating silicon carbide at room temperature of 23 °С.

Stage of progress

Initial stage.Silicon carbide synthesis was conducted in the laboratory conditions. Nanophase silicon carbide was generated. Research was carried out using high-precision equipment. According to the results of the diffractometric analysis the generated structures have silicon carbide phase, 4-H SiC polytype. The project needs to be continued in the framework of design and experimental works.


Patent of the Russian Federation No.2015152302“Production process of nanocomposite materials based on short carbon nanotubes”. D. A. Zhukalin, L.A. Bitutskaya, A.V. Tuchin.


1. Insufficient number of companies interested in the technology

Solutions:1) To provide information by organising specialised workshops.2) Direct meetings with heads of companies.3) To search partners on specialised forums.

2. Insufficient financingSolutions:1) To prepare and send out sponsorship packages to potential sponsors.2) To submit grant applications and to participate in contests for innovation projects financing.3) To cooperate with the administration of Voronezh State University.


Dmitry Zhukalin,PhD in Physics and Mathematics,Associate Professor at the Department of Semiconductor Physics and Microelectronics, the Faculty of Physics of Voronezh State University


The technology is of great importance for electronics producers all over the world. In the Voronezh region, such companies include: OAO Voronezh Semiconductor Plant, AO Research Institute of Electronic Technology, OAO Design and Engineering Centre “Elektronika”, OAO Concern Sozvezdie, and OOO AEDON.

Total cost (funding) of the project in roubles15,000,000 in the first year of the project and 2,000,000 in the following years.

Source of fundingGrant of the Russian Foundation for Basic Research 16-43-360281 “Physical and chemical foundations of silicon-carbide nanostructures low-temperature synthesis for extreme electronics electronic components base”.Applications for financial support of the project are being prepared or were submitted to a number of Russian foundations; negotiations are conducted with companies who have offered support to other research projects.

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Today, DLS-spectroscopy is used to measure colloidal particles. The goal of this project is to create a dielectric spectroscopy measurement system which allows not only inexpensive and efficient measurements but also statistical distribution of studied dispersions along particle sizes.


Integrated compact device that uses dielectric spectroscopy to measure the size of colloidal particles of 20nm and more with total weight of particles of several mg. In case of polydisperse colloids, the device enables to recapture the function of particles size distribution in a wide range of particles concentrations in the colloid solution.


• The device allows recapturing the function of particles size distribution;

• is compact and easy to operate;• is more reliable;• is cheaper.

Patent protection for the main technological solutions of the projectComputer program “Colloid KEF–16” № 2016619081 of 12.08.2016.

Enterprises that may be interested in the results of the projectEFKO Group of Companies, OOO Laska, and the Skolkovo Foundation.


Source of fundingGrants, subsidies, internal funds, and attracted funding. “The Fund for Promotion of Small Enterprises in Scientific and Technical Field” – contract № 11991Р/21889 of 27 June 2013, № 359 GS2/21889 of 01 April 2015, with total amount –3 million roubles. An investment contract was concluded with OOO Laska in the amount of 2 million roubles, and with OOO Polimer–V in the amount of 4 million roubles.

Stage of progress

Technical requirements for the colloidal particle size analyser based on the method of dielectric spectroscopy were developed; programmes and test methods for prototype models of the colloid particles size distribution analyser were developed.Prototype models of the colloid particles size distribution analyser were created. Laboratory testing of prototype models of the device were carried out to adjust the characteristics for further commercialization.

Development of colloidal particle size analyser based on the method of dielectric spectroscopy




• Environmental risks.• Marketing risks.• Technical risks.• Legal risks.• Commercial risks.• Financial risks.


OOO PlazmoSil, Alexander Lazarev, general director.

Spectroscopy

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Independent automated system “Smart Greenhouse”


• Failure of electronic equipment (sensors or microcontrollers). The risk of lack of components is highly unlikely.

• It may be impossible to use certain sensors if a greenhouse has complex structure.

• Marketing risks: failure to reach the planned turnover.

• Financial risks: low demand in non-agricultural regions.


Private agricultural companies and groups, such as OOO TK Eletskiye ovoschi, OOO Ovoschi Chernozemiya, TTs LipetskAgro.


Andrey Lun,PhD student of the Faculty of Physics, VSU.


An application was submitted to register the utility model “Independent automated system for microclimate control in greenhouses” (application No. 2017135897, submitted 9 October 2017).


Wider range of functions and options for the fine-tuning of greenhouse conditions according to the type of plants.


Source of fundingIt is planned to create a VSU-based small innovative enterprise to support the project.



A demo version of the independent automated system “Smart Greenhouse”.

Project product(s) (commercialised object)An independent system based on a unique algorithm for automatic adjustment of the conditions in greenhouses depending on the type of plants.

Stage of progressResearchers are now collecting real-life data at VSU's Botanical garden for the development of the algorithm.

Smart Greenhouse

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Creating hi-tech production of efficient multifunctional membrane units for high purity hydrogen evolution from hydrogen-containing gas mixtures

MEMBRANES

Project product(s) (commercialised object)Membrane units for hydrogen ultrapurification.

Stage of progressA technical proposal for the membrane unit is being developed.

As a result of the project, conducted jointly with the initiating enterprise, the following results will be gained.• A hi-tech production technology of efficient multifunctional membrane units for high purity hydrogen evolution from hydrogen-containing gas mixtures.• A prototype of an efficient multifunctional membrane unit for high purity hydrogen evolution from hydrogen-containing gas mixtures.• Hi-tech production of efficient multifunctional membrane units for high purity hydrogen evolution from hydrogen-containing gas mixtures.The proposed technology will be used to produce efficient multifunctional membrane units for high purity hydrogen (99,9999 %) evolution from hydrogen-containing gas mixtures. The proposed membrane unit will contain selective membrane elements based on thin films of palladium alloys. Within the framework of the project, VSU’s researchers will manufacture and test a laboratory version of the membrane unit. They will then, together with the partner enterprise, manufacture and test a prototype of this


The closet commercial analogue of the proposed technology is a FEL 50 – 150 membrane element, developed and produced as a test batch by the Institute of Petrochemical Synthesis of the Russian Academy of Sciences over 10 years ago. On the other hand, all the commercial membrane filtration systems used, are based on a selective layer of less than 30 μm, which makes such filters inefficient and expensive, and hence, the high price of ultrapure hydrogen. Thus, the major advantages of the proposed technology over the existing analogues are:• lower price;• low energy consumption of the unit;• significantly higher capacity.

membrane unit. The last stage of the project will include approval tests of the test sample, after which the enterprise will launch their production.

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Invention patent “Method for production of composite membranes from thin films of metals” RU2381055 was registered, and applications were prepared to patent the filter construction and the method for creating selective membranes.


The need for ultrapure hydrogen exists in many industries: energy (for hydrogen fuel cells), food, chemistry, electronics, steel, and space industries. The key consumers of ultrapure gaseous hydrogen in the Voronezh Region, who are greatly interested in applying effective membrane-based purification technologies are OAO KBKHA and AO VFSD Micron (Voronezh). Among the prospective consumers there is also OAO Novolipetsk Steel. The list of prospective customers in other regions includes companies specialising in scientific equipment, such as the company Novolab, the Manometer and Khromatograph plants, non-government funds Meta-chrome and TsvetChrome, as well as companies that use such chromatographs as the Tsvet-800, Stier, Cristallux, Cristall-10, etc., and want to upgrade their equipment.


Valentin Ievlev,head researcher, Full Member of the Russian Academy of Sciences, Head of the Department of Materials Science and the Industry of Nanosystems.

Alexander Maximenko,principal investigator of the project, researcher at the Department of Materials Science and the Industry of Nanosystems.


Financial and manufacturing risks.




Source of fundingFederal budget, inner financing of the initiator enterprise.

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Production line of ion-exchange membranes

ION-EXCHANGE MEMBRANES

Project product(s) (commercialised object)Next generation ion-exchange membranes and electrodialysis machines employing these membranes.


Payback period5 years. This time may be shorter if the number of orders is large enough.

Ion-exchange membranes are used in electrodialysis machines for filtering, separating and concentrating of substances. Electrodialysis technologies present a scalable system that can be used to solve various problems, such as industrial sewage disposal, synthesis and production of food and pharmaceutical products, as well as production of ultra pure water for thermal power stations, nuclear power stations and electronics industry. The machines that separate and concentrate acids and alkali use bipolar membranes, and the demand for these membranes has always been great. The project stages include modification of the existing types of ion-exchange membranes, development of new membranes, as well as design and testing of electrodialysis machines.As a result of the project, technological solutions for the production of ion-exchange membranes and electrodialysis machines will be developed, and laboratory and experimental-industrial electrodialysis machines will be tested in conditions which are as close as possible to the real-life production.


The major advantage of the proposed system is that the results were introduced and tested at real economic sector enterprises. The proposed advanced methods of ion-exchange membrane production can be easily adjusted to manufacturing conditions in Russia. Research in the area of bipolar membrane production resulted in a product which is in high demanded. Most of the patented methods for the production of bipolar membranes are rather complicated, not flexible enough, and hence, difficult to implement. The proposed ion-exchange membranes may be used to produce highly competitive import-substituting electrodeionisation machines for ultrapure water production.

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Participants of the project registered a number of patents for the ion-exchange membranes. The results of the intellectual activity were introduced to real economic sector enterprises in collaboration with OOO Innovative Enterprise Shchekinoazot. Patents for the results of development and application of electrodialysis technologies and the technologies for the production of next generation ion-exchange membranes are to be registered. Project’s initiator

(developer)

Pavel Kulintsov,PhD student and the leading engineer of the Department of Physical Chemistry of the Faculty of Chemistry.


Limited financial means of the customers. It may prove to be impossible to reach the technology efficiency level required by the customer. The quality of bipolar ion-exchange membranes produced by OOO Innovative Enterprise Shchekinoazot needs to be increased. Introduction of new types of bipolar membranes may result in higher production costs.

Stage of progress

Samples of modified membranes were synthesised, and prototypes of electrodialysis machines constructed. Intellectual property rights are protected by invention patents. Electrodialysis technologies are now being introduced at various enterprises in Russia and its neighbouring countries. The results of testing of the proposed technologies were presented at several Russian and international technological exhibitions.


Source of fundingR&D projects; targeted subsidies from the funds of the Ministry of Education and Science of the Russian Federation; investment by industrial partners; grants won within the framework of the federal target programme; participation in programmes within the framework of the Decree of the Government of the Russian Federation №218 "State support of development of cooperation between Russian universities and organisations that realise integrated hi-tech production projects”.


Electrodialysis technologies are widely used in the nuclear industry, as well as food, pharmaceutical, and chemical industries. The project is conducted jointly with AO Gidrogas and OOO Innovative Enterprise Shchekinoazot. Among the prospective customers are dairy industry enterprises in Russia and its neighbouring countries, as well as enterprises which are eager to increase the efficiency of raw material utilisation and lower the amount of industrial waste.

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Full-time hi-tech production of innovative water-retaining supersorbent Solid Water

Solid Water is a polymer, whose beads are sown in the field. The field is then watered. The polymers absorb water and function as automated reservoirs that maintain the humidity level in the soil. When the humidity level reduces, the beads release the water gradually so that it can get into the roots of plants. When it rains, or the field is watered, they absorb water again. This absorption-release cycle can repeat many times. 1 kg of the supersorbent absorbs up to 500 litres of water from the soil. It could be enough to fill the polymers with water once a year, and thus, even during dry periods agricultural plants will keep growing. Once sown in the field, the sorbent will function properly for 10 years.Various micro– and macroelements can also be added to the sorbent, thus transforming it into an organic fertilizer.The project has been conducted for 4 years using advanced equipment provided by Voronezh State University. The project is conducted jointly with Voronezh State Agricultural University.

SOLID WATER

Project product(s) (commercialised object)Supersorbent beads.

Stage of progressRefining the methodology of supersorbent synthesis and designing an advanced production unit.


The substrate proposed is an import-substituting solution. Solid water is cheaper than its foreign analogues.The main advantage is that the technology is adapted to the Russian climate and the beads are frost-resistant. Solid Water also has certain benefits for the environment as it improves the structure of the soil, and does not pollute or swamp it. When the beads’ lifespan is finished, they dissolve into non-toxic components. The advantage of the production method of Solid Water is that it uses industrial chemical agents and simple equipment that does not require great expenditure.

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1. Patent of the Russian Federation No.2574722Date of issue: 09.12.14.Method for obtaining hydrophilic cross-linked polymer with supersorbent propertiesPublished 10.02.2016. Statement No.4.Authors: V.A. Kuznetsov, V.F. Selemenev, V.N. Semenov, M.V. Bakalova.

2. Patent application No.2016110329 dated 21.03.2016.Methods for obtaining a supersorbent which contains microelements.Authors: V.A. Kuznetsov, I.V. Ostankova, V.F. Selemenev, V.N. Semenov, A.V. Zenischeva, A.L. Lukin, M.S. Lavlinskaya, A.N. Kharin.

3. Patent application No.2016110178 dated 21.03.2016.Method for obtaining water absorbing composite polymer material.Authors: V.A. Kuznetsov, V.F. Selemenev, V.N. Semenov, A.L. Lukin, I.V. Ostankova, M.S. Lavlinskaya, A.V. Zenischeva.


Source of fundingUniversity budget.


Duration of the project1.5 years


• Lack of financing to purchase equipment.• Intellectual property theft.• Equipment failure.• Increase in price of raw materials, energy

and water supply.


Vyacheslav Kuznetsov,DSc in Chemistry, Professor at the Department of High Molecular Compounds and Colloids of VSU.

Vladimir Selemenev,Prof., DSc in Chemistry, Head of the Department of Analytical Chemistry of VSU, Honoured Worker of Science of the Russian Federation.

Viktor Semenov,DSc in Chemistry, Professor at the Department of General and Inorganic Chemistry, Dean of the Faculty of Chemistry of VSU.

Alexey Lukin,DSc in Agriculture, Professor at Voronezh State Agricultural University.


• Agricultural companies.• Farms.• Fertilizer distribution centres.

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Development of energy-saving technologies used for the production of emulsifiers and emulsifying systems for food and non-food industry based on raw materials and their derivative products

EMULSIFIERS

The objective of the project is to develop high-performance energy-saving technologies used in the process of production of emulsifiers using renewable natural resources, including biocatalysts unprecedented in Russia and providing import substitution solutions in the industry.The proposed technology allows to:• recycle plant raw materials and

processing waste from oils;

Project product(s) (commercialised object)A wide range of high-performance emulsifiers based on plant oils and their processing waste.

Patent protection for the main technological solutions of the projectOne patent application was prepared, and two more are to be completed.

• produce a wide range of individual emulsifiers and emulsifying systems with set properties by modifying the fatty acid composition of a certain component.

The project’s products and the proposed technology have no analogues in Russia, and thus, the project will provide import substituting solutions in food emulsifiers industry.

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The project was initiated by OAO EFKO of the EFKO Group of companies.


At the moment, the following risks are highly probable: price and currency exchange rate fluctuations, manufacturing risks (equipment failure, various defects); Force Majeure.

Total cost (funding) of the project in roubles68 000 000, including 34 000 000 of subsidies, and another 34 000 000 of extra-budgetary funds.

Source of funding50% (34 000 000) – federal budget, 50% (34 000 000) – extra-budgetary funds.


Duration of the project27.10.2015 – 31.12.2017


Prospective consumers of the product are companies and enterprises working in food industry, cosmetics, personal hygiene products, household chemicals and cleaners and medical industries.OOO EFKO Food Ingredients is currently employing imported emulsifiers. The internal consumption market will thus total to 137 000 tons a year.

Stage of progress

Laboratory methods of synthesizing emulsifiers based on individual fatty acids and fatty acid model mixtures, oils and their processing waste, including monoglycerides, polyglycerol esters of different esterification degree, fatty acid alkanolamid sulfocationites and succinates, 2-alkyl-4-(2-hydroxyethyl)-imidazolines and their modification products, 5-alkyl-3-amino-1,2,4-triazoles and their modification products, 2-R-4-alkyl-5-amino-1,3,5-triazines, were developed.Consumer performance of the oil-based emulsifiers when used in food production was examined thanks to the investment by the industrial partner OAO EFKO. Laboratory methods of synthesizing emulsifiers based on plant oil and biocatalysis application were developed.


The competitiveness of the products is based on their lower production cost as compared to foreign and Russian analogues due to the fact that the enterprise uses its own raw material (sunflower, soya-bean oil, and palm oils) and wastes of oils and fats production, as well as advanced production technologies.

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Development of new corrosion inhibitors for non-ferrous metals based on the functional derivatives of aminotriazole


Risks connected with the current political and economic situation in Russia; risks associated with innovation projects; manufacturing risks.


An invention patent was registered, a patent application submitted. It is planned to register more patents.


Low production cost, wide range of derivatives, low price of end-products, high effectiveness at low concentration, high protection effectiveness.


Source of fundingInternal funds, prospective investors, the Foundation for Assistance to Small Innovative Enterprises in Science and Technology.



The objective of the project is to develop the production of functional derivatives of aminotriazole that demonstrate an anti-corrosion effect on the surface of non-ferrous metals. The first samples were received and their passivating power for copper examined. There are plans to expand the range of aminotriazole derivatives, as well as set up a production aimed at selling corrosion inhibitors.

Project product(s) (commercialised object)Corrosion inhibitors for non-ferrous metals.

Stage of progressPre-seed stage. Methods for synthesising derivatives of aminotriazole with proved passivating power were developed.


PAO Pigment (Tambov). OOO LKM Group (Lipetsk) and other paint material manufacturers. House management companies in Voronezh and the Voronezh Region. Production plants and large enterprises in Voronezh and the Voronezh Region.


Alexey Kruzhilin,PhD student of the Department of Organic Chemistry of the Faculty of Chemistry of VSU.

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We are headed towards the antibiotic apocalypse, as more and more bacteria are becoming resistant to the existing antibiotics. Rapidly mutating hospital and lung infections, supergerms and tuberculosis germs – these are just some of the bacteria that bring the apocalypse closer every day. Some governments, for example in the USA, Japan, and Korea, have already sounded the alarm. Within the next few years Big Pharma is going to complete clinical testing of only three germicides. With our project, we suggest a new approach to the design and production of antibiotics based on enzymes derived from bacteriophages and viruses. Such antibiotics function both as germicides and antifungals, and as preservatives in various food industries including the wine and cheese making industries.

Project product(s) (commercialised object)Broad-spectrum and narrow-spectrum antibiotics, antifungals, and preservatives for food industries.


Safe for humans, does not build up tolerance in bacteria and fungi even with long-term use, as it affects the fundamental metabolism processes of the target cells.

Patent protection for the main technological solutions of the projectKnow-how.


Pharmaceutical companies, food-producing companies.

Total cost (funding) of the project in roubles8 000 000 for R&D project.

Source of fundingInternal financing.

Stage of progress

Research and development. A functioning prototype of the antibiotic effective against Staphylococcus aureus was produced.

Molecular design and production of antibiotics and preservatives based on lytic bacteriophages and viruses

Duration of the project1 year.Payback period2 years.


None


The projects initiators and developers are members of a VSU-based small innovative business OOO Institute of System Biotechnologies.

Antibiotics

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Hyaluronic acid is a natural polysaccharide with various biological functions. It is one of the main components of vitreous humours, ligaments, joint capsules, and skin. Trauma– or age-related hyaluronic acid degradation results in joint pathologies, wrinkle formation, and loss of skin elasticity. In the past few years we have been studying various properties of enzymes derived from biosynthesis and biodegradation of hyaluronic acid. The results of the research allowed us to develop a technology for production of hyaluronate with a set molecular mass by bacteria and yeast cells.

Project product(s) (commercialised object)Technology for production of ultrapure hyaluronic acid.


The proposed production has no analogues in Russia. We suggest using hyaluronic acid in every cosmetic product, especially skin care products. The price of these products will rise only insignificantly, while they will acquire unique properties and, in mass production, will make the nation healthier and more beautiful.

Patent protection for the main technological solutions of the projectKnow-how. Patent applications will be submitted upon receiving sufficient financing.


Cosmetics manufacturers.

Total cost (funding) of the project in roubles12 000 000, of which 2 000 000 was already obtained from inner

funds.

Source of fundingInner financing, reinvestment of profits.

Stage of progress

The production line is being scaled. The first goods are being distributed through marketing networks. Ways and terms of distribution through federal pharmacy chains are being discussed. Sales started in September 2016. The sales volume at the moment is 100 000 roubles and is growing by at least 50% every month.

Microbial production of hyaluronic acid for the cosmetic and pharmaceutical industries

Duration of the projectIf we manage to attract sufficient investment, it will be possible to increase the output up to 300 kg

per month within 1.5 years.

Payback period2.5 years.


There are no commercialisation risks in cosmetic industry.


Small innovative business OOO Institute of system biotechnologies.

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Production of nutrient additives in the form of essential and limiting amino acids is a huge industry with thousand tons of output product, most of which is imported. We propose a type of bacteria that can produce amino acids, vitamins, and antigenic determinants of pathogens directly in animals’ gastrointestinal tracts. This will result in a weight gain of 5 to 10% depending on the animal. Using this nutrient additive it is also possible to feed animals with low-protein food without adding exogenic amino acids. The proposed bacteria do not differ from animal gut microflora, and are safe for humans – the consumers of the end product. The bacteria can also be used to synthesise vitamins and metabolic regulators, as well as antigenic determinants of pathogens that are not recognised by the immune system. It will thus be possible to perform immunisation by including certain bacteria into animal nutrition. Such bacteria will be available on sale in veterinary pharmacies not only for agricultural enterprises, but for individuals as well, which may help to prevent diseases such as bird flu and African swine fever.

Project product(s) (commercialised object)Bacterial feed additives.


A few milligrams of the proposed additive yield a weight gain comparable to that resulting from a few kilograms of amino acids.

Patent protection for the main technological solutions of the projectKnow-how.


Agricultural enterprises.

Total cost (funding) of the project in roubles5 000 000 to produce a prototype.

Source of fundingInternal financing.

Stage of progressR&D.

Nutrient additives for livestock animals

Duration of the project6 months

Payback period1 year


Technically, the additive contains GMOs, so legal risks are expected.


The projects initiators and developers are members of a VSU-based small innovative business OOO Institute of System Biotechnologies.

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Development of the technology of the common oak (Quercus robur L.) quickened growth for the reafforestation of the Central Black Earth Region

Introduction of the technology for the quickened growth of the common oak (Quercus robur L.) will help to solve some of the most urgent environmental and industrial problems of the Central Black Earth Region on federal, regional, and municipal levels. As a result of many years of research, a technology for the quickened growth of the common oak (Quercus robur L.) was developed. Various types of mixed soil were tested that quicken the growth of the common oak. The mixtures include peat, silt, humus, and various amounts of fertilizers. It takes a year to grow young plants to a usable size, when they have have strong rootstocks and enough leaves for photosynthesis. If the technology is introduced in a full-scale production, 150 000 young plants will be grown every year.

COMMON OAK

Project product(s) (commercialised object)Young plants of common oak; methodology for the quickened growth of trees and hardy-shrub plants.

Stage of progressSearch for investors.


1. Shorter growth time.2. Uses silt, which helps to solve the problem of waste disposal.3. Lower production cost.4. Using local soils.5. Year-round production.6. Large target market.

Total cost (funding) of the project in roubles1 850 000

Source of fundingExternal investors (including state institutions) interested in the implementation of the project. The project may also be interesting to owners or lessees of forest areas that need reforestation.




Two patent applications are ready to be submitted to the Federal service for intellectual property, patents, and trademarks. A patent in a similar area was registered (No.2498968, Russian Federation, IPC C05F5/00, C05F3/00. Method for utilising oil extraction manufacture wastes as fertiliser for tomatoes growing in black soil / T.A. Devyatova, K.Yu. Tolkalina, V.N. Kalaev, A.A. Voronin.: applicants and patent holders: Federal State-Funded Educational Institution of Higher Professional Education "Voronezh State University" (FSFEI HPE "VSU"). – 2012112005/13; submitted 29.03.2012; published 20.11.13, statement No. 32. – 8.).


Evgeniya Moiseeva,PhD in Biology, lecturer at the Department of Ecology and Land Resources of the Faculty of Biomedical Sciences and senior research fellow at the B.M. Kozo-Polyansky Botanical Garden of Voronezh State University.


• Thawing of the greenhouse facility in winter if the heating system fails.

• Plants becoming infected by diseases and pests.

• Failure to reach the planned turnover.• Lower sale price as compared to the

planned one.


There are several groups of prospective consumers.1. Participants of federal reafforestation

programmes.2. Lessees of forest areas.3. Agricultural enterprises and groups.4. Land and estate owners.5. Technologies for the quickened growth

of forest trees that can be employed for large-scale city landscaping, are now being developed. Some of these technologies aim at growing rare ornamental trees and shrubs widely used by landscape designers and gardeners (Phododendron L., in particular).

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DNA identification

The aim of the project is to create a laboratory where taxonomy identification will be performed during any development stage with no regard to the gender of the organism. The method consists of the decoding of a certain DNA segment of the organism and its comparison to the results presented in international databases. As a barcode, a cytochrome c oxidase subunit 1 gene of a mitochondrial DNA is used for animals, ITS – for fungi, rbcl and matK – for plants. Markers of this sequence will include nested PCR, TaqMan probes, molecular beacon probes, etc.

Project product(s) (commercialised object)A database comprising DNA cytochrome c oxidase genes for various species and their genetic markers. Biomaterial taxonomy identification services.

Stage of progress

The project is now in its final stage. The proposed analysis method was tested on organisms from various taxonomic groups, and their sequenced sequences were registered in the genbank system.

Development of a genetic identification method for biomaterial taxonomy based on DNA barcoding


The proposed identification method is an innovative one. The key difference of the proposed method from existing foreign analogues is that we are going to develop an information system compiling a set of genetic markers for each insect species. This will result in lower production cost, and will allow agricultural enterprises to simultaneously identify the taxonomy of a large number of insects belonging to different groups.


Two patent applications were submitted: “Differentiation method for commercially valuable Amblyseius mites based on restriction analysis” and “Identification method of Eurygaster integriceps based on restriction analysis of cytochrome c oxidase subunit 1 gene of a mitochondrial DNA”.


Manufacturing and commercial risk.


Prospective consumers of the product may include various research institutes, supervision bodies (Federal Service for Veterinary and Phytosanitary Surveillance, Federal Service on Customers' Rights Protection and Human Well-being Surveillance, etc.), quarantine service, customs bodies, farms, and agricultural organisations, in particular, ZAO Verofarm, and ZAO Molvest.


Source of fundingTo finish the research within this project it is necessary to obtain grants from Russian Foundation for Basic Research, federal target programmes, etc., or Bortnik Fund financing.




Anastasia Kokina,Lecturer, PhD student of the Department of Genetics, Cytology and Bioengineering of the Faculty of Biomedical Sciences of VSU.

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Development of biotechnologies for plant pollination and protection from pests and vermin in greenhouses

BIOCONTROL

Project product(s) (commercialised object)Predator mites — biological plant protection agents.

Stage of progressThe first import-substituting production of Phytoseiulus predator mites and predator Amblyseius swirskii mites that were separated from pests were created.


There are no analogues in Russia with similar functions. Advantages over existing foreign analogues: lower price and higher viability of mites due to shorter delivery time.

Predatory insects and mites are widely used for pest management of plants in greenhouses. Biological plant protection helps to fight pests which are resistant to pesticides, and thus cut down on the use of toxins and to achieve ecologically clean production. There are no, however, any specialised industries producing the most demanded biological protection agents. To meet the demand, it is necessary either to import these agents or to produce them in the in-plant laboratories.In Russia, the Amblyseius swirskii and Phytoseiulus predator mites are separated from a very dangerous plant pest, the spider mite. These are only produced by OOO Tekhnologii Shmelevodstva. The foreign importers present on the market are Biobest (Belgium), BioBee (Israel), Koppert (Netherlands). Total turnover of the imported Phytoseiulus mite is about 360 million mites. In 2016, the total greenhouse area in Russia was 2.17 thousand hectares. By 2020 it will be 3.5-4.6 thousand hectares. The demand for biological protection agents is growing in proportion to the growth of greenhouse areas, and will amount to 1,000 million roubles.

The target consumers of the project are national greenhouses. The project aims at developing an import-substituting production of predator mites for greenhouse facilities.


A.V. Lopatin, M.Yu. Syromyatnikov, D.V. Vostrikov, D.M. Gerasomiv, V.N. PopovA rearing cage for bumblebees, insects, and mites grown to protect plants from pests // Utility model patent No. 136683. Application No. 031385. Project No. 2013121285. Priority of the utility model registered on 13.05.2013. Registered in state utility models register of the Russian Federation on 20.01.2014. Patent-holders – OOO Tekhnologii Shmelevodstva, FSFEI HPE "VSU”.A.V. Lopatin, M.Yu. Syromyatnikov, D.V. Vostrikov, Malikova, V.N. PopovThe multicomponent substrate for the storage and transportation of biological plant protection agents and other small animals // Invention patent. Application: Application No. 056245. Project No. 2016135833. Date of receipt - 05.09.2016.

Enterprises that may be interested in the results of the projectGreenhouse facilities in Russia.


Payback period2025


New competitors. Decline in production by Russian greenhouse facilities due to lower prices on imported goods.

Полная стоимость (бюджет) проекта, руб.150 000 000.

Source of fundingGrant obtained within the Start 13 H5 programme of the Foundation for Assistance to Small Innovative Enterprises in Science and Technology – 1 000 000 roubles. Application No. 13-1-Н5.7-0189-1-С. Contract No. 12067р/22848 dated 25.07.2013. Project title – Development of biotechnologies for cucumber pollinating by bumblebees, and bumblebees control based on using devices for stimulating family initiation, as well as improvement of the laboratory methods of breeding Phytoseiulus predator mites. Federal State-Funded Educational Institution “Foundation for Assistance to Small Innovative Enterprises in Science and Technology”.Grant for the implementation of the project “Development of biotechnologies of plant pollination and protection in greenhouse facilities” provided by the Voronezh Region Economic Development Department – 1 000 000. Contract No. 7/B dated of 16.12.2013.Internal financing, including profit reinvestment.

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VSU-based small innovative enterprise OOO Tekhnologii Shmelevodstva and its CEO Alexey Lopatin, PhD in Biology, head researcher at the "Venevitinovo" Educational and Research Bioсentre.

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Development of unique equipment and consumable products manufacture for bumblebee farms and greenhouse facilities

BUMBLEBEE FARMS

Project product(s) (commercialised object)Bumblebee breeding technologies. Consumable products for bumblebee farms and greenhouse facilities which use bumblebees (food, medicine, etc.). R&D service.

Enterprises that may be interested in the results of the projectEvery bumblebee farm in Russia.

There are two specialised bumblebee farms, two greenhouse facility-based bumblebee laboratories, and a single enterprise OOO Tekhnologii Shmelevodstva, that develop unique technologies, equipment and consumable products for bumblebee farms in Russia. The technological gap between the leading bumblebee enterprises in Russia and most international companies has been practically eliminated thanks to introduction of technologies developed by OOO Tekhnologii Shmelevodstva. The development and introduction of new bumblebee breeding technologies can significantly reduce the cost of plant pollination by bumblebees. This can very much help in reaching a goal set for Russian greenhouse facilities for 2020 – to double the output of greenhouse vegetables. Local production of irreplaceable consumables for greenhouse facilities is a key component of a state’s food secutiry. Such consumables include bumblebees and consumable products – food, medicine, etc. The target consumers of the project are bumblebee farms in Russia. The products were developed, produced, and introduced by VSU researchers.

Total cost (funding) of the project in roubles3 500 000

Source of fundingState support subsidies to small innovative enterprises – 500 000 roubles, grants obtained from Department of Industry, Department of Transport, and Department of Innovations of the Voronezh Region.R&D grant for solving various problems in Voronezh. Voronezh administration, Mikhail Yurievich Syromyatnikov – 100 000 roubles."U.M.N.I.K." programme grant — 270 000 roubles. Innovation Technology Business competition prize received in 2011 – 20 000 roubles.Innovation Technology Business competition prize granted 2011 by Angstrem furniture production group – 20 000 roubles.Subsidies from the Voronezh budget granted to partly compensate for the expenditures of the small innovative business – 308 605 roubles.Inner financing, including profit reinvestment.


The proposed laboratory is the only large laboratory for developing bumblebee breeding technologies in Russia that does not belong to large bumblebee producers.


Know-how 102010000000029. Protein feed for bumblebees and honey bees with a pollen substitute preparation technique. License agreement No. 2/11 dated 11 October 2011. Accounting statement No. 381. License agreement No. 2/11 granting the right to use the results of intellectual activity.

A.V. Lopatin, M.Yu. Syromyatnikov Control method over cucumber pollination by bumblebees and honey bee // Invention patent No. 2485767. Application No. 062743. Project No. 2011141922/13(062743). Priority of the invention dated 18.10.2011. The patent was granted on 5 February 2013. Registered in the state register of the Russian Federation on 27.6.2013. Patent holder – OOO Tekhnologii Shmelevodstva

A.V. Lopatin, M.Yu. Syromyatnikov, G.K. Uskov, V.N. Popov A device for the stimulation of bumblebee colony development // Utility model patent No. 132947. Project No. 2013104015/13(005852). Priority of the utility model registered on 31.01.2013. The patent was granted on 15 March 2013. Registered in the state register of the Russian Federation on 10.10.2013. Patent holder – OOO Tekhnologii Shmelevodstva

A.V. Lopatin, M.Yu. Syromyatnikov, D.V. Vostrikov, D.M. Gerasomiv, V.N. Popov A rearing cage for bumblebees, insects, and mites grown to protect plants from pests // Utility model patent No. 136683. Application No. 031385. Project No. 2013121285. Priority of the utility model registered on 13.05.2013. Registered in


Payback period2017


VSU-based small innovative enterprise OOO Tekhnologii Shmelevodstva and its CEO Alexey Lopatin, PhD in Biology, head researcher at the "Venevitinovo" Educational and Research Bioсentre.

Stage of progressThe project resulted in the development of a unique hi-tech knowledge-intensive production of equipment and consumable products for bumblebee farms and greenhouse facilities which use bumblebees.

state utility models register of the Russian Federation on 20.01.2014. Patent-holders – OOO Tekhnologii Shmelevodstva, FSFEI HPE "VSU”.

A.V. Lopatin, M.Yu. Syromyatnikov, V.N. Popov Method for the evaluation of toxicity and nutritional value of feed for bumblebees and bees, bee-keeping products, and other food products based on artificial bumblebee microcolonies // Invention patent. Application: Application No. 056587. Project No. 2016136035. Date of receipt - 06.09.2016.


Decline in production by Russian bumblebee farms – the key consumers of the product.

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The suggested MRI contrast agent based on magnetic liposomes with magnetite nanoparticles is highly advantageous compared to the traditional chelated gadolinium complexes.

MRI contrast agent Lipocsan

Lipocsan

Project product(s) (commercialised object)MRI contrast agent based on stealth liposomes.

MRI contrast agents enhance the diagnostic capability of MRI and are used to determine the size of the tumour and improve the visibility of its internal body structures. They also help to identify metastases with more accuracy. Gadolinium(III) containing MRI contrast agents are some of the most commonly used. Being quite effective, gadolinium(III), however, is also highly toxic. The suggested MRI contrast agent is based on nanostructured magnetite which is incorporated into stealth liposomes. It is not toxic and helps to reduce the probability of side effects and allergic reactions.


Sources of funding• 2018-2020 - FTP “Research and

Development in Top-Priority Areas of Science and Technology in Russia for 2014-2020” activity 1.3 “Applied research aimed at developing new products and technologies”.

• In 2019, it is planned to obtain financing from the Fund for Promotion of Innovations in order to complete the project and conduct preclinical trial of the produced agent (Start 1 programme).

• In 2020, it is planned to continue cooperation with the Fund for Promotion of Innovations and obtain financing for the development of full-scale production of the suggested agent.

• It is also planned to obtain financing from the Fund for Promotion of Innovations within the Start 2 programme provided that the project will be co-financed from VSU’s internal funds.

• Inner financing.

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Patent research on “Development and production of the product. Patent research. Content requirements and procedure” was carried out in accordance with the requirements of GOST 15.011-96. The researchers working on the project also registered an invention patent (application No. RF2015147397 submitted 3 November, 2015) “Production of liposomes” (patent No. RU2621145 registered by V.G.Artyukhov, I.A.Koltakov, and E.V.Shilova). While conducting the R&D project on the production of the Lipocsan MRI contrast agent, the researchers also developed new methods of production and processing of nanostructured magnetite as well as new methods for incorporating nanostructured magnetite into lopisomes. It is, therefore, possible to submit applications for the registration of the intellectual property rights on the obtained samples and developed methods.

Duration of the project2018 – 2027

Payback time6 years.

Project’s initiator(developer)

Igor Koltakov, associate professor at the Department of Biophysics and Biotechnology of the the Faculty of Biology and Soil Sciences, VSU.

Stage of progressFinal stage of the R&D project.


• Research and technical risks. • Production risks. • Market risks. • Financial risks. • Human resources risks.


• Leading medical centres and research laboratories in Voronezh and the Central Black Earth Region.

• State and private diagnostic centres with MRI equipment.

• Leading pharmaceutical companies that promote new products on European and world markets.

Major consumers in the Voronezh Region will be the following:• Voronezh Regional Clinical Diagnostic

Centre; • Interregional centre for early diagnostics

and treatment of oncology diseases; • Voronezh regional children's clinical

hospital; • Diagnostic and treatment centre of

the International Institute of Biological Systems;

• Chernozemiye medical centre; • MRI-Expert.

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Development of innovative encapsulated dosage forms based on microcapsules

ENCAPSULATED DOSAGE FORMS

One of the goals of the development strategy for the pharmaceutical industry of the Russian Federation up to the year 2020 is promotion of the development, production and export of innovative medicinal products, among other things by creating additional financing mechanisms to support innovative projects.Modern medicine and pharmacy are focsued on developing new neuroleptic agents. Today, one of the most popular and desirable dosage forms is microcapsules, which, among other things, make it possible to decrease the extent to which the substance stability is influenced by humidity. Placing microcapsules inside capsules can

result in a significant prolongation of the pharmacological effect. For that, a number of technological solutions are needed, specifically: It is necessary to develop the microencapsulation technology and to select the optimal auxiliary substances. The development of the technology for new dosage forms of afobazol enables us to obtain medicinal products that will outperform in many ways the existing dosage forms, i.e. tablets.Successful implementation of the project will result in a new competitive product on the pharmaceutical market that will have a number of advantages compared to alternative dosage forms.

Project product(s) (commercialised object)Afobazol sustained-action anxiolithic capsules.

Stage of progressTechnological and pharmacological studies aimed at the development of the product were competed.

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• Sustained action that enables reducing the dosage frequency from 3 times (tablets) to once (capsules) a day.

• 1.8 reduction of the cost of the protracted treatment – from 550 roubles to 200 roubles.


An application for the patent “Methods of producing anxiolithic capsules” is being prepared.

Enterprises that may be interested in the results of the projectPharmaceutical companies that produce solid-dosage forms.


• Failure to produce the desired dosage form discovered during the process of non-clinical and clinical studies.

• A product with the same characteristics launched by another company.




Source of funding• U.M.N.I.K programme (“Developing the

formula and performing a technological study of microencapsulated pharmaceutical forms of afobazol”).

• Grant of the President of the Russian Federation (“Methodological aspects of developing new dosage forms based on microcapsules”)


Yulia Polkovnikova,PhD in Pharmaceutics, lecturer at the Department of Pharmaceutical Chemistry and Pharmaceutical Engineering of Voronezh State University

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Development of an innovative technology for the generation of wound healing multi-enzymatic medication “ZAZHIVIN”

ZAZHIVIN

A technology for heterogeneous enzyme preparations for medical purposes was developed. The preparations combine low toxicity and low allergic response with higher clinical effectiveness compared to existing similar products. A pilot batch of heterogeneous enzyme preparations was produced. They will serve as an active substance of the medicinal products used locally to treat wounds, burns, chancres, post-operative suture, and scars.

Project product(s) (commercialised object)A safe and modern alternative to antibiotics and chemotherapeutic agents used to treat wounds and wound infections, including those that are antibiotic resistant.


Compared to existing similar products the developed enzymic preparations will have the following characteristics: high clinical effectiveness; sustained action; low toxicity and allergic response, and as a result safe in case of chronic administration; lower concentration of the active substance, and lower price.


The Voronezh region has pharmaceutical manufacturing companies (ZAO Areal, OOO Experimental Pharmaceutical Plant №1, OOO Experimental Pharmaceutical Plant №2, OOO NPP Avitsenna, etc.) that can be involved in the production of the end product, which will be developed as a result of the project.A wide range of institutions can be interested in the results of the project: sanitation-and-epidemiological, medical, and veterinary institutions that deal with pathogenic and opportunistic pathogenic microflora.

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• Application № 2017123458 of 03.07.2017 “Production process of a heterogeneous preparation of different dispersity based on bromelin and chitosan” / M.G. Kholyavka, V.G. Artyukhov, V.A. Koroleva

• Application № 2017123459 of 03.07.2017 “Production process of a heterogeneous preparation based on bromelin with wound healing properties” / M.G. Kholyavka, V.G. Artyukhov, S.M. Sazykina

• Application № 2017123462 of 03.07.2017 “Production process of a heterogeneous enzymic preparation with wound healing and regenerating properties” / M.G. Kholyavka, V.G. Artyukhov, V.A. Koroleva

• Application № 2017123460 of 03.07.2017 “Production process of a heterogeneous preparation based on collagenase and chitosan” / M.G. Kholyavka, V.G. Artyukhov, S.S. Olshannikova

• Application № 2017123457 of 03.07.2017 “Production process of a heterogeneous preparation based on papaine” / M.G. Kholyavka, V.G. Artyukhov, V.A. Koroleva

Total cost (funding) of the project in roublesApproximately 6,000,000.

Source of fundingIt is planned to obtain Bortnik Fund financing (U.M.N.I.K. And START programmes) and Federal Target Programmes financing. To take part in the START programme it is planned to create a small innovative business in Voronezh State University in accordance with Federal law №217.Among other expected sources of funding are subsidies provided in the framework of the governmental support of small and medium businesses by subjects of the Russian Federation in accordance with article 78 of the Budgetary Code of the Russian Federation and the Decree of the Government of the Russian Federation of 27.02.2009 № 178.

Payback periodApproximately 8 years.

Duration of the project7-8 years.


Commercialisation risks are twice as high as risk average and are 18-20%. The major risks can result from insufficient financing of the project during the R&D stage and potential industrial espionage.

Stage of progress

The technological solutions of the project are based on research results. Trypsin, bromelin, ficine, papaine, and collagenase were immobilized on chitosan of various polymerization levels and VION fibres. A method of trypsin immobilization on chitosan which enables to save up to 94% of the enzyme activity was suggested. The optimum functioning conditions for the preparations were determined. Their physical and chemical and kinetic properties were investigated.


Marina Kholyavka,PhD in Biology, researcher, associate professor at the Department of Biophysics and Biotechnology of the Faculty of Biology and Soil Sciences of Voronezh State University.

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Development of an innovative wound healing medicine “RANNET”

RANNET

A model composition of a gel based on chitosan, taurine, and allantoin was developed. A large number of samples of developed gels were used to select the optimal composition of active and auxiliary substances which meets all the necessary requirements (pasting, swelling properties, transparency, and homogeneity). Apparent the wound healing properties of the obtained model gel composition were revealed. It reduces wound healing time of wounds by 47.94%.

Project product(s) (commercialised object)Rannet gel composition.

Stage of progressLaboratory study.


The global market offers a wide range of wound healing medicinal products. However, they fail to fully provide the desired wound healing action. Today, the closest competitor to the suggested product is a wound healing hydrogel with iodovidon and anilocaine produced by OOO APPOLO. The gel prevents the tissue from drying and traumatizing, contributes to the lysis of necrotic tissues, and provides for the wound drainage. Moreover, RPO ArgoVasna offers a wide spectrum propolis gel which also has

wound healing properties. Another wound healing product is Levomekol ointment. However, it can be allergic and can cause agranulocytosis. Solkoseril gel has gained a reputation of an efficient wound healing product. However, 1 tube (20 grams) costs over 200 roubles. Moreover, the product does not have an antibacterial action. Despite a wide spectrum of pharmacological activities these products have a number of disadvantages: intolerance to ingredients; these gels do not minimize cicatrization; and have a relatively narrow spectrum of action. The developed composition of RANNET gel does not have the above mentioned disadvantages.

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The decision to grant a patent of the Russian Federation was received.

Enterprises that may be interested in the results of the project• ZAO Rafarma,• OAO Nizhfarm,• ZAO Verofarm,• OAO Akrikhin,• AstraZeneka,• STADA CIS,• ZAO VERTEKS.


Source of fundingGrants of the Russian Federation “Russian Foundation for Basic Research”, founders’ funds, and venture investment.


Payback period14 months


Research and technical risks – possibility of negative R&D result is very low as the first products were developed as a result of preliminary research. Technical risks will also be minimized as allocation of the budget funds will allow conducting sufficient research and design and experimental work and to develop solutions of the required quality. Negative results can be eliminated due to technological advances and the qualifications of the involved researchers who have been successfully working on similar projects in related fields for over 5 years.Industrial risks – possibility of failure to master production is very low as the manufacturing process management has been certified. The manufacturing equipment wear and tear is below 25%. Shortage of components can be ruled out as at least 3 independent suppliers will be used to supply each component.Commercial risks – all calculations used for the business model are based on the analysis of the economic performance of the existing industrial units, the situation on the market of pharmaceutical equipment and expert assessment of leading specialists from international companies involved in similar production.Conjunctural risks are minimized due to the analysis of data concerning promising projects conducted by competitors. The data were received at annual international exhibitions and conferences dedicated to cell technologies.


Pavel Fedosov,post-graduate student of the Department of Pharmacology of the Faculty of Pharmaceutics of Voronezh State University

Sales risks – developed products will have a lower price and a shorter payback period compared to imported products. It is of great importance for potential customers.Financial risks – there is a possibility of failure to find financing to cover the organisation of project activities. To mitigate these risks it is planned to take part in grant and subsidy competitions in the framework of programmes aimed at the support of entrepreneurial activity.

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Development of Pavlovsk Mining and Concentration Complex screening processing technology focused on enhancing the market demand for them and decreasing the environmental impact

HEAVY MINERALS

Project product(s) (commercialised object)The products of the stone screening dust procession are zirconium, ilmenine, rutile, and magnetite concentrates, as well as fractions classified according to the size of the particles.


This technology offers lower production cost for concentrates extraction compared to similar productions as it allows complete procession of each component of the stone screening dust and its further sale.

The operation of Pavlovsk Mining and Concentration Complex has led to the accumulation of about 30 million tonnes of stone screening dust. Its mineral composition has been studied and an innovative technology for its waste-free recycling has been developed. It classifies the stone screening dust into three fractions according to the size of the particles with the following extraction of heavy concentrates. The main application area for the first fraction is filling material for asphalt coating. Potential consumers of the second fraction are manufacturers of reinforced concrete products. The third fraction is the most valuable component of the stone screening dust, as it has such minerals as magnetite, ilmenite, rutile, and zirconium. Magnetite is used in ferrous metallurgy and the electrochemical industry. Ilmenite and rutile are high-demand materials in titanium sponge and titanium white production, which are used in the chemical and steel industries. Zirconium concentrate is a highly valuable material and a material of strategic importance.


Duration of the projectMaturity of the technology – 1 year.


Source of funding• Attraction

of external investors interested in the implementation of the project.

• Attraction of public investment.

• Attraction of funding from the State Foundation for Assistance to the Voronezh Region Small Innovative Enterprises.


At the current stage patent application documentation is being prepared.


Dmitry Shevtsov,post-graduate student of the Faculty of Geology of Voronezh State University, lecturer at the Department of General Geology and Geodynamics.


The most crucial commercialisation risks are changes on the sales market. There is also a small risk of losing material resources as a result of unscheduled shutdown of Pavlovsk Mining and Concentration Complex.Among unaccounted factors are: sustainable financing of the project at the earlier stages, equipment delivery and assembly schedules, qualified staff, and other mounting and design works. However, all the above mentioned factors are not crucial for the project implementation.

Stage of progress

The project is being tuned, including more detailed studies of the heavy mineral fraction of the stone screening dust and the most promising methods of extraction. Experimental equipment is being developed for the initial stage of the technology introduction into the full-scale production.


Companies specialising in asphalt production, distribution, and laying and production of reinforced concrete products.The results of the project are of high interest for organisations that purchase zirconium, ilmenine, and rutile concentrates from abroad, as well as for Pavlovsk Mining and Concentration Complex.

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CONTACTS

Address 1 Universitetskaya Ploschad, Voronezh, 394018, Russia Tel. +7 (473) 220-75-21 Russian telegraph office, Voronezh, 22 Fax. +7 (473) 220-87-55 E-mail [email protected]

Director of VSU Innovation Business Incubator, DSc in Technical Sciences, associate professor Alexander Dmitriyevich Khvan Tel. +7 (473) 220-81-35

Translated by Irina Charychanskaya Yulia Dymant

Edited by Simon Cox Designed by VSU department of marketing and advertising

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