Quiz 2 ReviewKristine Krafts, M.D.

Quiz 2 Review

• Immunology Overview

• Hypersensitivity

• Immune Lab Tests

Quiz 2 Review

• Immunology Overview

class I MHC moleculeclass II MHC molecule

class II MHC genes class I MHC genesclass III MHC genes

MHC complex

class II MHC genes class I MHC genesclass III MHC genes

MHC genes are polymorphic!

class II MHC genes class I MHC genesclass III MHC genes

MHC genes are polymorphic =many normal variants!

Quiz 2 Review

• Immunology Overview

• Hypersensitivity

Type I:Allergy

Opsonization and phagocytosis

Type II: Antibody

Type III:Immune complex

Delayed-Type Hypersensitivity (DTH)

T-cell-mediated cytotoxicity

Type IV: T-cell

Quiz 2 Review

• Immunology Overview

• Hypersensitivity

• Immune Lab Tests

patient red cells + AHG = agglutination

patient Ab + AHG = agglutinationdonor

RBC = Ab-coateddonor RBC +