Quality control of Baby Care Products by Ashwini
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Transcript of Quality control of Baby Care Products by Ashwini
G.ASHWINI
M.PHARMACY 1/1
ROLL NO 100809885003
OUCT
QUALITY CONTROL OF
BABY POWDERS AND
SHAMPOOS
G.ASHWINI
M.PHARMACY 1/1
ROLL NO : 100809885003
OUCT
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CONTENTS
INTRODUCTION
ANATOMICAL DIFFERENCE BETWEEN
BABY AND ADULT SKIN
PHYSIOLOGICAL DIFFERENCE BETWEEN
BABY AND ADULT SKIN
BABY POWDERS
FORMULATION
EVALUATION
BABY SHAMPOOS
FORMULATION
EVALUATION
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Need different skin and hair care
Their exist anatomical and physiological differences
The skin of the newborn is “unripe”.
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EPIDERMIS:
Only in prematures
The stratum corneum is lacking, a significant barrier function , photoprotection, immunological barrier, and receptor function, respectively—still has to develop progressively.
The stratum germinativum , melanocytes are less pigmented, which explains the pale color of the newborn’s skin.
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In the dermis, numerous fibroblasts produce elastic and collagen fibers but fewer in
number than in adult life.
It is known that the dermal matrix differs in
composition depending on age. Indeed, during
development, the water, glycogen, and hyaluronic acid contents of the matrix
decrease, but its dermatan sulfate content increases
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Dermal absorption in newborn skin is similar to that observed in adult skin. For babies, however, a number of typical risk factors exist.
The surface area/body weight ratio is 2.3-fold higher in newborns than in adults .
Pharmacokinetic parameters differ widely between babies and adults .
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BABY CARE PRODUCTS:
Baby care products are defined as the paediatric cosmetics which usually contain harmless ingredients that make no or therapeutic value and is used more or less to prevent rather than cure undesirable skin problems.
Different kinds of baby care products are baby creams, baby lotions, baby oils, baby powders, baby shampoos, etc..,.
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BABY
POWDERS
BABY POWDERS
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Formulation:
Talc : 70% Magnesium stearate : 6.0%
light calcium : 24.0%
carbonate
Perfume : q.s
Baby powders are used for
the maintenance of
Epidermal physiology and the
skin care in the new borns.
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Shade control and lighting: Pressure testing: Flow property Particle size determination
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Abrasiveness
Breakage test
Stability
Sterlity test
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BABY SHAMPOOS
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FORMULATION: Surfactants 15-30%
Foam Stabilizers 1-4 %
Thickener 0-5%
Deionized Water Q.S
Baby shampoos are
used to clean the scalp
and the hair of the
babies
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Preservatives 0,1-1 %
Humectants 1-5 %
PH Buffers Q.S. neutral pH
Chelating Agents 0-0,02 %
Pearlescing/ opacifying agents 0,2-2%
Perfume 0,5-1 %
Colouring agents Q.S.
Conditioning agents Q.S. desired effect
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Evaluation of Safety Skin toxicity test.
Eye toxicity test.
Evaluation of antimicrobial activity
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six rabbilts are selected
On skin of each rabbit round patch is made by removing hair
Dilute preparations of 8-10% are applied on to patches of all
rabbits
Shampoo is allowed to for aperiod of 3-4 hrs and wash it
completely
After effieicent washing skin is observed for any adverse
reactions
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Six rabbits are selected
Test eye control eye
Apply product
Wash it after 20 sec,
5min and 24 hrs
Observe at 1hr,24hrs,48hrs,
7th day and 14th day
Washed on first day and after 24
hrs
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Since shampoos are liquid or viscous preparations, they are liable to microbial growth. Hence the preservative is added to prevent the microbial growth. This test is usually done by a method called as “Challenge study”.
According to this study, the product is said to be preserved when it does not support microbial growth even after repeated attacks of various micro-organisms.
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Intially app. Starin of micro organism is selceted and is considered
as test organism
Culture of test organism is prepared
The product is inoculted repeated in culture media and studies are
Carried out for 10- 12 weeks
Along with test ,control samples are prepared and reserved for reference
Usaually two types of control samples are prepared i.e., one sample
long with preservative and with out preservative
The test comes to conclusion only when it has been proven that has not
supportedMicrobial growth www.pharmacygraduates.org
Baby skin is very sensitive than adult, so we should take a lot of care
What ever we are applying should be
Non toxic
Non irritant
Free from microbial contamination
Totally it must be mild and Safer to use.
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Sharma PP. Cosmetics-formulation, manufacturing
and quality control. 3rd ed., Vandana Publications
Pvt. Ltd., Delhi, 2005.
Nanda S, Nanda A, Khar RK. Cosmetic technology.
Brila Publications Pvt. Ltd., Delhi, 2007.
Amparo Salvador, Alberto Chisvert. Analysis of
Cosmetics products. 1st ed., Elsevier Publications
Pvt. Ltd., U.K, 2007.
Andre O. Barel, Marc Paye, Howard I. Maibach.
Hand book of Cosmetic Science and Technology.
3rd ed., Informa Healthcare USA, 2009.
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