Phol 480: Pulmonary Physiology Section Session 3: Control Instructor Jeff Overholt
Pulmonary Disease ANATOMY & PHYSIOLOGY 13-14. Fact or Myth?
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Transcript of Pulmonary Disease ANATOMY & PHYSIOLOGY 13-14. Fact or Myth?
Pulmonary DiseaseANATOMY & PHYSIOLOGY 13-14
Fact or Myth?
ASTHMA & ANCIENT EGYPT
Cures For Asthma
3,400 B.C.
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Strammonium Flower
1 A.D.Smoking dried fox liver
1860
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Talking Cure
ASTHMA ATTACKS
Levalbuterol
Restrictive v. Obstructive Lung Disease
Obstructive Pulmonary Diseases
• Noted by impediments to normal movement of air through the conducting passageways of the respiratory tract
• Examples:• Asthma: Increased contractability of smooth muscle surrounding conductive
passageways. Common chronic inflammatory disease• Bronchitis: Bacterial or environmental inflammation of mucous membranes of
bronchi and bronchioles• Chronic Obstructive Pulmonary Disease (COPD): Persistent and cumulative
breakdown of lung tissue. Condition couples the anatomical breakdown of lung tissue (emphysema) with physiological narrowing of asthma/bronchitis. Most commonly associated with smoking. 4th leading cause of death worldwide
• Emphysema : Anatomical breakdown of lung tissue• Epiglottitis: Bacterial infection of epiglottis, which can lead to a completely closed
trachea
Restrictive Pulmonary Disease
• Def: Diseases that prevent lung expansion, reduce lung volume or demand increased work to allow ventilation
• Examples:• Cystic Fibrosis: Genetic mutation that leads to excess mucus production in the lung and
scarring/fibroids in the pancreas• Mesothelioma: Tumor formation in the pleura, preventing inflation of the lung• Pneumonia: Viral or bacterial disease that fills alveoli with fluid, hindering oxygenation• Sarcoidosis: Autoimmune or environmentally-triggered disease leading to chronic
formation of inflammatory cells (granulomas) in the lungs, reducing lung volume• Tuberculosis: Bacterial disease leading to granuloma formation in lungs. Highly
communicable.
Evaluation of Pulmonary Disease