Public Health Impact

Basic Science

Discovery

Translational Research Continuum

Proposed Human Application

Proven Clinical Application(clinical trials)

Clinical Practice(effectiveness or outcomes research)

T1 Lab to clinical

T2 Safety/efficacy

T3 Implementation

& adoptionDissemination

Adapted from:Woolf, The meaning of translational research and why it matters, JAMA, 2008Drolet & Lorenzi. Translational research: understanding the continuum…, Translational Research, 2011.

SEC Obesity Prevention Symposium - 2014

Obesity Prevention

Genetic Influences

Physiology

Early Life Influences

Environmental Influences

Interventions Family, School,

Community & Workplace

Technology Community

ActionsPolicy

*Ya-Ziong Tao(Anatomy, Physiology,

Pharmacology

*Danielle Wadsworth

(Kineseology)

*Bonnie Sanderson; *Ann Lambert (Nursing)

*Jan Kavookjian (Pharmacy)

* AU presenters

http://www.secsymposium.com

Does this resemble a “Cluster” in Translational Research?

Health Concern

Genetic Influences

Physiology

Human Influences

Environment Influences

Interventions

Community Actions

Health Policy

T1 Lab to clinical

T2 Safety/efficacy

T3 Implementation

& adoption

Dissemination

School of Nursing- Research Focus

Translational (“T-3”) & dissemination with multidisciplinary collaborationObesity prevention Diabetes – self management skillsCVD- prevention thru management; Elderly & chronic disease – caregivingPet-assisted therapyMilitary – wounded warriorSimulation Health disparity and underserved

populations

Nursing Research Opportunities

Build on current strengths:Outcomes Research - “Big data” Intervention research

◦Health disparities◦CVD and risk factors - prevention and disease management

Expand potential abilities:“T1 and T2” collaborations

◦Nursing physiologist; genetics◦Nursing informatics◦Biostatistician

Current priority research initiatives:End-of-Life and Palliative CareSymptom - Pain

◦ Biology of pain◦ Assessment and management of pain

http://www.ninr.nih.gov/researchandfunding

Examples funding agencies applicable for nursing:• NIH – R-15; R-21• AHRQ; PCORI • HRSA• AHA; ADA; CDC

What or who is needed?

AU – Strategic Focus in Cluster Hire in Health SciencePrioritize health concern

◦Public Health and Alabama need◦Align with funding opportunities

Consider full spectrum of Translational Research◦Identify and “harness” the current AU talent

and expertise ◦Identify the gaps for target hires within the

translational continuum