PROS AND CONS ABOUT SWEETENER ASPARTAME USED IN SOFTDRINKS et al

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    PROS AND CONSON THE CONTROVERSIAL

    SWEETENER

    ASPARTAMEUSED IN

    SOFTDRINKS & JUICES ET AL

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    A. IN FAVOR OF ASPARTAME BY WIKIPEDIA:

    Aspartame

    Aspartam[1]

    IUPAC !am[hide]

    N-(L--Aspartyl)-L-phenylalanine,

    1-methyl ester

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    http://en.wikipedia.org/wiki/Aspartame#cite_note-1http://en.wikipedia.org/wiki/International_Union_of_Pure_and_Applied_Chemistry_nomenclaturehttp://en.wikipedia.org/wiki/Aspartamehttp://en.wikipedia.org/wiki/Aspartamehttp://en.wikipedia.org/wiki/File:Aspartame_sample.jpghttp://en.wikipedia.org/wiki/File:Aspartame-from-hydrate-xtal-2000-3D-balls.pnghttp://en.wikipedia.org/wiki/File:Aspartame.svghttp://en.wikipedia.org/wiki/Aspartame#cite_note-1http://en.wikipedia.org/wiki/International_Union_of_Pure_and_Applied_Chemistry_nomenclaturehttp://en.wikipedia.org/wiki/Aspartame
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    Aspartame(APM; / s p r tem/!r /s p rtem/" #s a$ art#%#a' $!$)

    sa&&*ar#+es,eete$er-se+ as a s-ar s-st#t-te#$ s!me %!!+s a$+ e0eraes. I$

    t*e E-r!pea$ 1$#!$ #t #s &!+#%#e+ as E234. Aspartame #s a met*5'ester!%

    t*e aspart#& a+/p*e$5'a'a$#$e+#pept#+e. It ,as %#rst s!'+ -$+er t*e ra$+

    $ame N-traS,eet; s#$&e 6772 #t a's! *as ee$ s!'+ -$+er t*e ra$+ $ame

    Am#$!S,eet.89It ,as %#rst s5$t*es#e+ #$ 42e&t !% se0era' p!'#t#&a' a$+ me+#&a'

    &!$tr!0ers#es &!$ress#!$a' *ear#$sa$+ I$ter$et *!a=es8?838!#$e+ #$t! a$ a$*5+r#+e a$+t*e am#$! r!-p #s pr!te&te+ 5 a &!mp!-$+ t*at ,#'' pre0e$t %-rt*er rea&t#!$s !% t*atr!-p. P*e$5'a'a$#$e #s met*5'ate+ a$+ &!m#$e+ ,#t* t*e N)pr!te&te+ aspart#&a$*5+r#+e t*e$ t*e '!$ r!-p #s rem!0e+ %r!m aspart#& a+ 5 a+ *5+r!'5s#s.T*e +ra,a& !% t*#s te&*$#G-e #s t*at a 5pr!+-&t t*e #tter tast#$ H)%!rm #spr!+-&e+ ,*e$ t*e ,r!$ &ar!=5' r!-p %r!m aspart#& a+ '#$s t! p*e$5'a'a$#$e. Apr!&ess -s#$ a$ e$5me %r!m Bacillus thermoproteolyticus t! &ata'5e t*e

    &!$+e$sat#!$ !% t*e &*em#&a''5 a'tere+ am#$! a+s ,#'' pr!+-&e *#* 5#e'+s ,#t*!-tt*e H)%!rm 5pr!+-&t. A 0ar#a$t !% t*#s met*!+ ,*#&* *as $!t ee$ -se+&!mmera''5 -ses -$m!+#%#e+ aspart#& a+ -t pr!+-&es '!, 5#e'+s. Met*!+s %!r+#re&t'5 pr!+-$ aspart5')p*e$5'a'a$#$e 5 e$5mat#& mea$s %!''!,e+ 5 &*em#&a'met*5'at#!$ *a0e a's! ee$ tr#e+ -t $!t s&a'e+ %!r #$+-str#a' pr!+-&t#!$.844

    Pr!pert#es a$+ -se

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pedia.org/wiki/Phenylalaninehttp://en.wikipedia.org/wiki/Acidhttp://en.wikipedia.org/wiki/Base_(chemistry)http://en.wikipedia.org/wiki/Methanolhttp://en.wikipedia.org/wiki/Hydrolysishttp://en.wikipedia.org/wiki/Peptide_bondhttp://en.wikipedia.org/wiki/Peptide_bondhttp://en.wikipedia.org/wiki/Hydrolyzedhttp://en.wikipedia.org/wiki/Aspartame#cite_note-9http://en.wikipedia.org/wiki/Aspartame#cite_note-odonnell-10http://en.wikipedia.org/wiki/Thermolysinhttp://en.wikipedia.org/wiki/Aspartame#cite_note-11
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    Beta)aspartame +#%%ers %r!m aspartame ase+ -p!$ ,*#&* &ar!=5' r!-p !%

    aspartate #$+s t! t*e $#tr!e$ !% p*e$5'a'a$#$e.

    Aspartame a$ art#%#a' s,eete$er #s appr!=#mate'5 677 t#mes s,eeter t*a$ s-&r!se!r ta'e s-ar. D-e t! t*#s pr!pert5 e0e$ t*!-* aspartame pr!+-&es %!-r#'!&a'!r#es !% e$er5 per ram ,*e$ meta!'#e+ t*e G-a$t#t5 !% aspartame $ee+e+t! pr!+-&e a s,eet taste #s s! sma'' t*at #ts &a'!r#& &!$tr#-t#!$ #s $e'##'e.8@T*etaste !% aspartame a$+ !t*er art#%#a' s,eete$ers +#%%ers %r!m t*at !% ta'e s-ar #$t*e t#mes !% !$set a$+ *!, '!$ t*e s,eet$ess 'asts t*!-* aspartame &!mes&'!sest t! s-ars taste pr!%#'e am!$ appr!0e+ art#%#a' s,eete$ers.847T*es,eet$ess !% aspartame 'asts '!$er t*a$ s-&r!se s! #t #s !%te$ 'e$+e+ ,#t* !t*er

    art#%#a' s,eete$ers s-&* as a&es-'%ame p!tass#-mt! pr!+-&e a$ !0era'' taste m!re'#e s-ar.846Aspartame &a$ e s5$t*es#e+ %r!m #ts &!$st#t-e$t am#$! a+s )p*e$5'a'a$#$ea$+ )aspartate.

    #e ma$5 !t*er pept#+es aspartame ma5 *5+r!'5e(rea +!,$" #$t! #ts &!$st#t-e$tam#$! a+s -$+er &!$+#t#!$s !% e'e0ate+ temperat-re !r *#* pC. T*#s maesaspartame -$+es#ra'e as a a#$ s,eete$er a$+ pr!$e t! +era+at#!$ #$ pr!+-&ts*!st#$ a *#* pC as reG-#re+ %!r a '!$ s*e'% '#%e. T*e sta#'#t5 !% aspartame -$+er*eat#$ &a$ e #mpr!0e+ t! s!me e=te$t 5 e$&as#$ #t #$ %ats !r #$ma't!+e=tr#$. T*esta#'#t5 ,*e$ +#ss!'0e+ #$ ,ater +epe$+s mare+'5 !$ pC. At r!!m temperat-re #t #sm!st sta'e at pC ?.9 ,*ere #ts *a'%)'#%e#s $ear'5 977 +a5s. At pC *!,e0er #ts *a'%)'#%e#s !$'5 a %e, +a5s. M!st s!%t)+r#$s *a0e a pC et,ee$ 9 a$+ 3 ,*ere aspartame#s reas!$a'5 sta'e. I$ pr!+-&ts t*at ma5 reG-#re a '!$er s*e'% '#%e s-&*as s5r-ps%!r %!-$ta#$ e0eraes aspartame #s s!met#mes 'e$+e+ ,#t* a m!resta'e s,eete$er s-&* as sa&&*ar#$.849

    Aspartames ma>!r +e&!mp!s#t#!$ pr!+-&ts are #ts &5&'#&+#pept#+e(#$ a 63)+#et!p#pera#$e !r DKP %!rm" t*e +e)ester#%#e+ +#pept#+e (aspart5')p*e$5'a'a$#$e"a$+ #ts &!$st#t-e$t &!mp!$e$tsp*e$5'a'a$#$e84?aspart#& a+843a$+ met*a$!'.84

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    Aspartame ,as +#s&!0ere+ #$ 42

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    I$#t#a''5 aspartame ,as appr!0e+ 5 t*e 1.S. F!!+ a$+ Dr- A+m#$#strat#!$(FDA" #$42? *!,e0er pr!'ems ,#t* Sear'es sa%et5 test#$ pr!ram #$&'-+#$ test#$ !%aspartame ,ere +#s&!0ere+ s-seG-e$t'5. T*e appr!0a' ,as res$+e+ t*e %!''!,#$5ear -t a%ter !-ts#+e re0#e,s !% t*e pr!'emat#& tests a$+ a++#t#!$a' test#$ %#$a'appr!0a' ,as ra$te+ #$ 42@4. Be&a-se a''eat#!$s !%&!$%'#&ts !% #$terestmarre+ t*eFDAs appr!0a' !% aspartame8894896t*e 1.S. L!0er$me$t A&&!-$ta#'#t5

    O%%#&ere0#e,e+ t*e a&t#!$s !% #$0!'0e+ !%%#a's #$ 42@< a$+ t*e appr!0a' pr!&ess #$42@; $e#t*er t*e a''eat#!$s !% &!$%'#&t !% #$terest $!r pr!'ems #$ t*e %#$a' appr!0a'pr!&ess ,ere s-sta$t#ate+.8899

    I$ a++#t#!$ t*e e$ters %!r D#sease !$tr!' #$0est#ate+ #$ 42@? a$+ ,as -$a'e t!%#$+ a$5 s#$#%#&a$t ep#+em#!'!#&a'ass!at#!$s t! ser#!-s r#s !r *arm.89?

    S#$&e De&emer 422@ a ,#+e'5 r&-'ate+ ema#' *!a= te+ aspartame as t*e &a-se!% $-mer!-s +#seases.893

    T*e ,e#*t !% e=#st#$ se$t#%#& e0#+e$&e #$+#&ates t*at aspartame #s sa%e at &-rre$t'e0e's !% &!$s-mpt#!$ as a $!$)$-tr#t#0e s,eete$er.8@Re0#e,s &!$+-&te+ 5

    re-'at!r5 ae$es +e&a+es a%ter aspartame ,as %#rst appr!0e+ *a0e s-pp!rte+ #ts&!$t#$-e+ a0a#'a#'#t5.89

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    %r-#t +r#$s a$+ &*e,#$ -m am!$ !t*ers #$ sma''er G-a$t#t#es.8@A 46 1S %'-#+!-$&e (933 m'" &a$ !% +#et s!+a &!$ta#$s 4@7 m#''#rams (7.77

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    B. AGAINST ASPARTAME

    If a product is approved by the Food and Dru Administration (FDA) and composed of natural

    inredients, !ould you assume it is safe to consume"

    If the same product is an artificial sweetener, !ould you assume it helps control your !eiht"

    #illions of people use aspartame, the artificial s!eetener $no!n as %utra&!eet '#, !ith these assumptionsin mind

    o!ever, aspartame*s tainted history of approval and potentially to+ic inredients cast serious doubt on

    the safety of this suar substitute Furthermore, aspartame may actually increase your appetite (Farber )

    .hile the FDA approval may sinal the reen liht for safe consumption, / percent of all complaintsreistered !ith the FDA are for adverse reactions to aspartame, includin five reported deaths A closer

    loo$ at the unscientific studies, suspicious approval methods, and its harmful inredients, reveal the

    hidden daners of this artificial s!eetener In reality, aspartame poses a public health threat

    Over 10,000 Complaints

    'he FDA has received over 10,000 complaints reardin adverse reactions to aspartame y the FDA2so!n admission, less than 1 percent of those !ho e+perience a reaction to a product ever report it 'his

    means that the 10,000 documented accounts probably mean that there are rouhly a million people !ho

    have e+perienced reactions to aspartame

    .hile a variety of symptoms have been reported, almost t!o-thirds of them fall into the neuroloical andbehavioral cateory consistin mostly of headaches, mood alterations, and hallucinations 'he remainin

    third is mostly astrointestinal symptoms

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    .here is aspartame found or used"

    Aspartame, sold as %utra&!eet or 34ual, is an artificial s!eetener, present in over 5000 products It is

    responsible for a host of health problems, includin brain diseases, miraines and psycholoical ailments

    Dr 6 7oberts has called aspartame 8an inored epidemic9 -- his database contains over 1,:00 reports

    of adverse reactions to aspartame

    ;;;;;

    Aspartame can be found in thousands of products such asuice beveraes

    la+atives

    multivitamins

    mil$ drin$s

    pharmaceuticals and supplements, includin

    over-the-counter medicines

    sha$e mi+es

    soft drin$s

    tabletop s!eeteners

    tea beveraes

    instant teas and coffees

    toppin mi+es

    !ine coolers

    yourt

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    Ailments Resulting From Aspartame

    'he components of aspartamecan lead to a !ide variety of ailments &ome of these problems occur

    radually !hile others are immediate, acute reactions

    A fe! of the many disorders associated !ith aspartame include the follo!inority -- 5H percent O of complainants also reported

    neuroloicalPbehavioral symptoms

    &ome of the most commonly reported neuroloical symptoms includeournalEnvironmental Health PerspectivesM+iiN statesob of e+plainin, in layman*s terms, !hat

    aspartame is made of, and ho! patients have, and can, test their vulnerability to this chemical usincessation and rechallene (I !ill also offer further suestions on ho! to do this at the end of this article)

    'his type of anecdotal evidence, !hich critics love to dismiss as silly nonsense, can nonetheless be

    invaluable to the individual in 4uestion, as you can clearly discover !hether there*s a direct cause and

    effect on your body from consumin aspartame

    Dr 6 7oberts is one of several e+pert investiators on aspartame and has testified before conress onthe topic of aspartame safety

    In a document titled,?rofessional pinion of 6 7oberts, #D, FAG?, FGG?, Goncernin

    eadaches Gaused by the se of ?roducts Gontainin Aspartame, he states thatects !ere iven

    pure aspartame administered as capsules or in cold !ater %o consumer !ill ever inest aspartame in this

    form

    !/citoto/icit#

    Aspartame has three components< phenylalanine, aspartic acid, and methanol (!ood alcohol) 'hose !ho

    defend the chemical arue that phenylalanine and aspartic acid are a harmless and natural part of your diet

    ?henylalanine and aspartic acid are indeed amino acids that are normally supplied by the foods you eato!ever, they can only be considered natural and harmless !hen they are consumed in combination !ith

    other amino acids, fats, and carbohydrates in the form of real food

    .hen phenylalanine and aspartic acid are consumed as free amino acids, they enter your central nervous

    system in abnormally hih concentrations, causin e+cessive firin of brain neurons and potential cell

    death 'his concept has been termed 8e+citoto+icity9 by Dr 7ussell layloc$, a prominent neurosureon

    Blin"ness an" Cancer

    ?otentially even more !orrisome is the 10 percent of aspartame that is absorbed into your bloodstream as

    methanol 'he 3nvironmental ?rotection Aency defines safe consumption of this danerous substance as

    no more than H/ millirams per day, !hich is the amount found in half a can of diet soda #ethanolpoisonin can result in fatal $idney damae, blindness, multiple oran system failure and death

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    'he manufacturers of aspartame aain defend the methanol by claimin it is found naturally in many

    foods ut in nature, methanol is bound to pectin, a form of fiber As a result of this bond, your body is not

    e+posed to methanol, nor does it brea$ it do!n o!ever, your body does absorb the pectin-free methanolin aspartame, and further brea$s it do!n into formaldehyde

    Formaldehyde can accumulate !ithin your cells, and react !ith other cellular proteins such as en=ymes

    and D%A Formaldehyde can cause cancer in laboratory animals and li$ely causes cancer in humans

    'here is no $no!n threshold level belo! !hich there is no threat of cancer

    Are 'ou aving a Reaction

    If you thin$ you may be havin a reaction to aspartame, you miht !ant to consider doin an

    eliminationPchallene !ith it First eliminate it (and all other artificial s!eeteners) from your diet

    completely for a period of one to t!o !ee$s After this period, reintroduce it in a sinificant 4uantity Fore+ample, use it in your beverae in the mornin, and eat at least t!o aspartame containin products the

    remainder of the day Avoid other artificial s!eeteners on this day

    Do this for a period of one to three days %otice ho! your body is feelin, particularly if it feels different

    than !hen you !ere artificial s!eetener free %early t!o-thirds of aspartame reactors e+periencedsymptomatic improvement !ithin t!o days after avoidin aspartame .ith continued abstinence, their

    complaints enerally disappeared

    Lastly, report your reaction to any aspartame product bycallin the FDA Gonsumer Gomplaint

    Goordinatorin your area

    Source:

    .!erco"a.co!

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    h# "on2t we hear aout these things

    'he reason many people do not hear about serious reactions to aspartame is t!ofold< 1) Lac$ of a!areness

    by the eneral population Aspartame-caused diseases are not reported in the ne!spapers li$e plane

    crashes 'his is because these incidents occur one at a time in thousands of different locations across thenited &tates ) #ost people do not associate their symptoms !ith the lon-term use of aspartame Forthe people !ho have $illed a sinificant percentae of their brain cells and thereby caused a chronic

    illness, there is no !ay that they !ould normally associate such an illness !ith aspartame consumption

    o! aspartame !as approved is a lesson in ho! chemical and pharmaceutical companies can manipulate

    overnment aencies such as the FDA, BbribeB orani=ations such as the American Dietetic Association,and flood the scientific community !ith fla!ed and fraudulent industry-sponsored studies funded by the

    ma$ers of aspartame

    3ri$ #illstone, a researcher at the &cience ?olicy 7esearch nit of &usse+ niversity has compiled

    thousands of paes of evidence, some of !hich have been obtained usin the freedom of information act:, sho!in< 1 Laboratory tests !ere fa$ed and daners !ere concealed 'umors !ere removed from

    animals and animals that had died !ere Brestored to lifeB in laboratory records : False and misleadin

    statements !ere made to the FDA 'he t!o & Attorneys iven the tas$ of brinin fraud charesaainst the aspartame manufacturer too$ positions !ith the manufacturer*s la! firm, lettin the statute of

    limitations run out 'he Gommissioner of the FDA overruled the ob>ections of the FDA*s o!n scientific

    board of in4uiry &hortly after that decision, he too$ a position !ith urson-#arsteller, the firm in chareof public relations for @D &earle

    A ?ublic oard of In4uiry (?I) !as conducted in 1/0 'here !ere three scientists !ho revie!ed the

    ob>ections of lney and 'urner to the approval of aspartame 'hey voted unanimously aainst aspartame*s

    approval 'he FDA Gommissioner, Dr Arthur ull ayes, 6r then created a -person &cientificGommission to revie! the ?I findins After it became clear that the Gommission !ould uphold the

    ?I*s decision by a vote of : to , another person !as added to the Gommission, creatin a deadloc$ed

    vote 'his allo!ed the FDA Gommissioner to brea$ the deadloc$ and approve aspartame for dry oods in1/1 Dr 6ac4ueline Rerrett, the &enior &cientist in an FDA ureau of Foods revie! team created in

    Auust 1HH to revie! the ressler 7eport (a report that detailed @D &earle*s abuses durin the pre-

    approval testin) said< BIt !as pretty obvious that some!here alon the line, the bureau officials !ere!or$in up to a !hite!ashB In 1/H, Rerrett testified before the & &enate statin that the e+periments

    conducted by &earle !ere a BdisasterB &he stated that her team !as instructed not to comment on or be

    concerned !ith the overall validity of the studies &he stated that 4uestions about birth defects have not

    been ans!ered &he continued her testimony by discussin the fact that DE? has been sho!n to increaseuterine polyps and chane blood cholesterol and that increasin the temperature of the product leads to an

    increase in production of DE?(1:)

    S)*r+, Aspartam-s H.//! Da!0rs.!erco"a.co!

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  • 8/13/2019 PROS AND CONS ABOUT SWEETENER ASPARTAME USED IN SOFTDRINKS et al

    19/25

    All .n"ustr#3Fun"e" %tu"ies 4ive Aspartame Clean Bill of ealth,

    hile +a5orit# of .n"epen"ent Research Fin" .n"ications of

    a&ar"s

    A 15 revie! of 15 studiesMviiN MviiiNbelieved to be relevant to human safety, by Dr 7alph @ .alton, a

    professor of Glinical ?sychiatry, sho!ed a remar$able discrepancy bet!een study results and their sourceof fundin

    f the 15 studies, H had industry related fundin (such as &earle, %utras!eetS, A>inomoto, and the

    International Life &ciences Institute %utrition Foundation), and 1 !ere independently funded

    f thoseority of the s!eetness 'hat phenylalanine

    methyl bond, called a methyl ester and is very !ea$

    If the methyl alcohol is removed from aspartame as easily happens !hen drin$s s!eetened !ith it aree+posed to hiher temperatures, it no loner tastes s!eet 'his is precisely !hat happened to most of the

    diet soda sent to the #iddle 3ast for & troops 'hey received non s!eet sodas that !ere loaded !ith

    danerous levels of methanol !hich is more or less li$e drin$in straiht poison !hen it*s in this alreadybro$en do!n state

    Dr #onte e+plains the history of ho! methanol found its !ay into our food supply