Propranolol_ Drug Information
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Official reprint from UpToDate ® www.uptodate.com ©2013 UpToDate ® Propranolol: Dr ug information Copyrigh t 1978- 2013 Lexicomp, Inc. All rights reserv ed. (For additional information see "P ropra nolol: Pat ient drug information" and see "Propranolol: Pediatric drug info rmation" ) For abbreviations and symbols that may be used in Lexicomp ( show table ) ALERT: U.S. Boxed Warning The FDA-appr ov ed labeling includes a boxed warnin g. S ee Warnings/Precautions secti on for a concis e summary of this information. For verbatim wording of the boxed warning, consult the product labeling or www.fda.gov . Brand Names: U.S. Inderal LA; InnoPran XL Brand Names: Canada Apo-Propranolol®; Dom-Propranolol; Inderal®; Inderal® LA; Novo-Pranol; Nu-Propranolol; PMS-Propranolol; Propranolol Hydrochloride Injection, USP; Teva-Propranolol Pharmacologic Category Antianginal Agent; Antiarrhythmic Agent, Class II; Beta-Blocker, Nonselective Dosing: Adult Akathisia (unlabeled use): Oral: 30-120 mg/day in 2-3 divided doses Es s entia l tre mor: Oral: 40 mg twice daily initially; maintenance doses: Usually 120-320 mg/day Hypertension: Initial: Oral: 40 mg twice daily; increase dosage every 3-7 days; usual dose: 120-240 mg divided in 2-3 doses/day; maximum daily dose: 640 mg; usual dosage range (JNC 7): 40-160 mg/day in 2 divided doses Extended release formulations: Inderal® LA: Initial: 80 mg once daily; usual maintenance: 120-160 mg once daily; maximum daily dose: 640 mg; usual dosage range (JNC 7): 60-180 mg/day once daily InnoPran XL®: Initial: 80 mg once daily at bedtime; if initial response is inadequate, may be increased at 2-3 week intervals to a maximum dose of 120 mg Hypertrophic subaortic stenosis: Oral: 20-40 mg 3-4 times/day
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