Project Unity: The Way of the Future for Plant Breeding
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Transcript of Project Unity: The Way of the Future for Plant Breeding
Phenome Networks Confidential
Unleashing innovation through next generation bio-informatics
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PLANT BREEDING COMPANIES GENERATE ENDLESS DATA
It is stored in sub-optimal datastores such as notes, excels and local solutions.
NO ONE HAS CONSOLIDATED ACCESS TO THE SUM OF DATA FROM PUBLIC RESEARCH
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A large financial investment goes to waste
5,000STUDIES
$100KEACH
$500MINVESTMENT
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Impossible today
Study
1
Study
2
Combinedinsights
1+2
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What if we could standardize phenotype and genotype vocabulary?
• Linking genomics to traditional breeding• Share and compare data from multiple research groups
(standardization)• Link to other academic public-domain data
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Phenome Networks Confidential
Genetic research works to correlate genotypes with phenotypes
MILLIONS OF GENETIC MARKERS
Onestudy, one
population
POPULATION /ENVIRONMENT
POPULATION / ENVIRONMENT
POPULATION / ENVIRONMENT
PH
EN
OT
YP
ES
Large investment
Vast amount of data
Complex analysis
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Many research groups are working.In isolation.
MILLIONS OF GENETIC MARKERS
POPULATION /ENVIRONMENT
POPULATION / ENVIRONMENT
POPULATION / ENVIRONMENT
PH
EN
OT
YP
ES
Onestudy, one
population
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Phenome Networks Confidential
Sharing and collaboration among multiple groups is challenging
?
HISDATA
ADHOCEXCELSHEET
PDF REPORTSMY
DATA
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Phenome Networks Confidential
Missing crucial insights
MILLIONS OF GENETIC MARKERS
POPULATION /ENVIRONMENT
POPULATION / ENVIRONMENT
POPULATION / ENVIRONMENT
PH
EN
OT
YP
ES
Oneproject,
onepopulation
Other traits affected by my favorite marker?
Impact of my markers in other populations?
Are the effects consistent in different environments?
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Standardization is needed…
Phenotype Germplasm Genotype
Trait 1
Trait 2
Trait 3
Trait’s ontology
Unify scales
Germplasm 1
Germplasm 2
Germplasm 3
Pedigree relations
Define source
Marker 1
Marker 2
Marker 3
Link to genetic / physical map
Germplasm
Phenotype Genotype
Metadata on experiments / populations
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Phenome Networks Confidential
In an ideal world we want to innovate by integrating data from multiple sources
MILLIONS OF GENETIC MARKERS
POPULATION /ENVIRONMENT
POPULATION / ENVIRONMENT
POPULATION / ENVIRONMENT
PH
EN
OT
YP
ES
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PublicPrivate
Giving Private Access to Public Data
Register, without central admins
Upload data
Analyze data
Integrate with public academic
data
Share data and
findings
21 3 4
Search dataSearch resultsCorrelateGet alerts
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UNITY: Aggregating all phenotypes / genotypes of all species in one place
PHENOME-NETWORKS
SGN GRAMENE NCBI PANZEA
PapersPapersPapers Papers
Papers
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Phenome Networks Confidential
UNITY: unleashing new insights by combining information about the world’s species
Study
1
Study
2
Combinedinsights
1+2
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We are in private beta.
For more information, go here:
http://phenome-networks.com/unity/