PrograM noVEMbEr 1 (thu)lmce-kslm.org/html/user/core/view/basic/main/45/mail/...department of...

Patient-CenteredLaboratory Medicine

LMCE 2018 &KSLM 59th Annual Meeting

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introduCtion

SY 03 (Kor)

Education course forlaboratory medicine

specialist　

PRE-CONGRESS 01

Patient centered laboratory medicine

(Women's health,Cardiac disease,

Oncology)

PRE-CONGRESS 02

PL 01

08:00

09:00

10:00

11:00

12:00

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17:00

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19:00

20:00

SY 01 (Kor)

The current status ofhealthcare-associated

infection (HAI) and the roleof clinical microbiology MSACL

Clinical mass spectrometry workshop

SY 02 (Kor)

Inspector workshop ofthe Korean laboratoryaccreditation program

SY 04 (Kor)

MFDS-KSLM SessionIn vitro diagnostics

device registration andmodification for MFDS

Blood type and personality – Asian mythology(Walkerhill Theatre, B1)

Opening Ceremony(Walkerhill Theatre, B1)

Welcome Reception(Vista Hall 1, B2)

Floor

Walker Hall 1 Walker Hall 2 Cosmos Hall Art Hall

4F3F1F

Room

PrograM _ noVEMbEr 1 (thu)

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November 1-3, 2018Grand Walkerhill Hotel, Seoul, Korea

intr

oduC

tion

KS 02

OP 02

Floor B2

Vista Hall 1 Walker Hall 1

EW 02 EW 03 EW 04 EW 05EW 01

EW 06

SY 05

SY 07

PL 02

OP 01

New moleculartechnologies for

personalized medicine

Clinical chemistry 1

Walker Hall 2 Cosmos Hall Art Hall

4F3F1F

Room

Break

Break

KS 01Clinical pathologists and taking

care of patients in the clinic

SY 06

Statistics & ethics for laboratory researches

Clinical laboratoryreimbursement

- Financial aspects oflaboratory medicine

AACC-KSLM Select Session Expanding the measurable metabolome: How should we mine the lipidome?

(Vista Hall 1, B2)

SY 09 SY 10

Education track I

SY 08

Practical aspects of laboratory management IV;

Laboratory InformationSystem (LIS) & Information

CommunicationTechnology (ICT)

Genomics of human leukocyte antigen (HLA)

in the era of next generation

sequencing (NGS)

Clinical microbiology

OP 03

Generallaboratory medicine &Transfusion medicine

OP 05SY 12 OP 04

Education track IISY 11

Accreditation system for the

clinical laboratory

Diagnostic genetics 1& Diagnostichematology

Strategies to optimize medicallaboratory for patient care

in the era of universal coverage

Clinical chemistry 2& Diagnosticimmunology

SY 13

AACC-KSLM Select Session

Emerging clinicalapplications for circulating DNA

analysis

Banquet(Walkerhill Theatre, B1)

08:00

09:00

10:00

11:00

12:00

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14:00

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19:00

20:00

Senate Meeting

PrograM _ noVEMbEr 2 (fri)

PL: Plenary LectureKS: Keynote SpeechSY: SymposiumEW: Education WorkshopOP: Oral PresentationKor: Korean



22

introduCtion

SY 19

Guidelines onclinical tests for

patient care

SY 20

Role of specialists intransfusion medicine

ESCMID-KSLMSession

Precision medicine ininfectious diseases

KSLM General Assembly (Vista Hall 1, B2)

KS 04Integrative analyses of microbiota,

immunity & environment can transform (laboratory) medicine

EW 07 EW 08 EW 09 EW 10 EW 11

PL 03

The fight against antimicrobial resistance: Are we doing right?(Vista Hall 1, B2)

08:00

09:00

10:00

11:00

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16:00

17:00

18:00

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20:00

SY 15SY 14 OP 06

Diagnostic genetics 2

Break

Recent trends inclinical chemistry for optimal patients care

SY 16 SY 17 (Kor)

Updates in laboratoryhematology

KCDC-KSLMSession

Legislation fordiagnostic tests:

National regulationor supports

CLSI-KSLMSession

Customer focused documents of CLSI

SY 18

KS 03Bioactive lipids in

laboratory medicine

Floor B2

Vista Hall 1 Cosmos Hall Art Hall

4F3F1F

Room Walker Hall 1 Walker Hall 2

PL: Plenary LectureKS: Keynote SpeechSY: SymposiumEW: Education WorkshopOP: Oral PresentationKor: Korean

PrograM _ noVEMbEr 3 (sat)

Scientific Program-

Plenary SPeakerS

keynote SPeakerS

SymPoSium DeScriPtion

Daily Program- november 1

- november 2

- november 3

PoSter PreSentation

PLENARY SPEAKERS

50

SCIENTIFIC PROGRAM



PL03november 3 (Sat), 11:00-12:00 | Vista Hall 1 (B2)

the fight against antimicrobial resistance: are we doing right?

Jesús Rodríguez BañoUniversity of Sevilla, Spain

PL02 aacc-KSLm Select Sessionnovember 2 (fri), 11:00-12:00 | Vista Hall 1 (B2)

expanding the measurable metabolome: How should we mine the lipidome?

Dennis J. DietzenWashington University School of medicine, USa

PL01november 1 (thu), 17:30-18:30 | Walkerhill theatre (B1)

Blood type and personality - asian mythology

Kyou-Sup HanSeoul national University college of medicine, Korea

KEYNOTE SPEAKERS

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KS04november 3 (Sat), 13:00-13:40 | Vista Hall 1 (B2)

integrative analyses of microbiota, immunity & environment can transform (laboratory) medicine

Shuji OginoHarvard medical School, Brigham and Women’s Hospital, Dana-farber cancer institute, Harvard t.H. chan School of Public Health, and Broad institute of mit and Harvard, USa

KS02november 2 (fri), 17:00-17:40 | Vista Hall 1 (B2)

Strategies to optimize medical laboratory for patient care in the era of universal coverage

Lia G Partakusumanational cardiovascular centre Harapan Kita, indonesia

KS01november 2 (fri), 08:00-08:40 | Vista Hall 1 (B2)

clinical pathologists and taking care of patients in the clinic

Seongsoo JangUniversity of Ulsan college of medicine, Korea

KS03november 3 (Sat), 08:00-08:40 | Vista Hall 1 (B2)

Bioactive lipids in laboratory medicine

Yutaka Yatomithe University of tokyo graduate School of medicine, Japan



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SCIENTIFIC PROGRAM


SYmPOSium 01 (korean)

the current status of healthcare-associated infection (Hai) and the role of clinical microbiologythis session will manage the current situation of healthcare-associated infections in Korea, especially from the point of view of carbapenem-producing enterobacteriaecae, which is a notorious emerging threat in many countries, and the role of the clinical microbiology laboratory in overcoming the public threat will be discussed.


inspector workshop of the korean laboratory accreditation programthis workshop deals with the accreditation checklist and intends to improve understanding and practical skills required of inspection team leaders and members.


education course for laboratory medicine specialistthis session has been organized to provide specialists a chance for continuing education in the department of laboratory medicine, including diagnostic hematology, clinical chemistry, diagnostic immunology, clinical microbiology, transfusion medicine, and diagnostic genetics. this program is operated under Korean medical Law and will introduce the current issues of each sub-specialty regarding clinical practices and resident training.

SYmPOSium 04: mFDS-KSLm SeSSiOn (korean)

Joint Workshop with the ministry of Food and Drug Safety (mFDS) and kSlm industry-academia-government (iag) committee: in vitro diagnostics device registration and modification for mFDSto share the mfDS registration experience in iVD trials and report to mfDS for a minor change of iVD, this workshop, organized by the KSLm iag committee and mfDS, will help principal investigators (Pi) and iVD developers understand the process of registering and minor change reports to mfDS for iVD.

SYmPOSium 05

Statistics & ethics for laboratory researches

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SYmPOSium 06

clinical laboratory reimbursement – Financial aspects of laboratory medicine

SYmPOSium 07

new molecular technologies for personalized medicineadvances in molecular technologies are expanding the scope of personalized medicine, a tailoring of medical treatment based on an individual's genetic profile, especially in the field of medical oncology. topics to be presented in this session will focus on the development and clinical applications of new molecular technologies that drive personalized and precision medicine.

SYmPOSium 08

Practical aspects of laboratory management iV; laboratory information System (liS) & information communication technology (ict)the ‘Laboratory management committee’ will introduce the basic principles of the Laboratory information System (LiS), maximizing the value of test results with information communication technology (ict), and middle Ware applications & ict, which are essential elements for effective laboratory management.

SYmPOSium 09

education track iaccording to the revised eligibility criteria policy, the specialized education of each division will be needed in addition to common education course. therefore, this session aims to admitted professional qualities required as an educational supervisor and a resident in training and to improve the problem solving capabilities when working in the laboratory. in this session, we will go over for the updated laboratory diagnosis in the fields of immunology, microbiology and genetics.

SYmPOSium 10

genomics of human leukocyte antigen (Hla) in the era of next generation sequencing (ngS)We would like to share the recent application of ngS technology in HLa genomics, particularly related with disease association and transplantation.



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SCIENTIFIC PROGRAM


SYmPOSium 11

accreditation system for the clinical laboratory

SYmPOSium 12

education track iiaccording to the revised eligibility criteria policy, specialized education for each division will be needed in addition to general education courses. therefore, this session aims at the professional qualities required as an educational supervisor and resident in training and to improve the problem-solving capabilities when working in the laboratory. the special divisions covered in this session are clinical chemistry, diagnostic hematology, transfusion medicine, and clinical microbiology and will give us the latest practical information.

SYmPOSium 13: AACC-KSLm SeLeCt SeSSiOn

emerging clinical applications for circulating Dna analysismuch recent progress has been achieved in the analysis of circulating graft-derived and tumor-derived Dna. Some of these new applications have been or will soon be implemented clinically for organ transplantation monitoring and cancer screening/diagnosis. in this session, details of clinical studies, technological and molecular approaches as well as new biological understanding of circulating Dna will be shared.

SYmPOSium 14: CLSi-KSLm SeSSiOn

customer focused documents of clSi

SYmPOSium 15

recent trends in clinical chemistry for optimal patients carea hormone is a chemical substance produced in the body by an organ, cells of an organ, or scattered cells, having a specific regulatory effect on the activity of organs. for optimal patient care, accurate and specific measurement of hormones such as vitamin D, thyroid hormones, and testosterone is important. these hormones are measured by a variety of analytical techniques, including bioassay, immunoassay, and mass spectrometry interfaced with liquid chromatography. in this section, we will provide useful information about the analytical details for individual hormones using such techniques and clinical implications of these hormones assays.

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SYmPOSium 16

updates in laboratory hematologyin every discipline of laboratory hematology, we are continuously confronting challenges as the understanding of diseases and clinical practices improve and evolve. essential and inspiring updates in diverse fields covered here will help to stimulate research in laboratory hematology and make clinical services more complete.

SYmPOSium 17: KCDC-KSLm SeSSiOn (korean)

legislation for diagnostic tests: national regulation or supportsenactment and support of legislation is required to perform appropriate diagnostic tests and strengthen the capacity of the laboratory. in Korea, the area of clinical laboratory testing has continuously expanded over time and proper legislation for the clinical laboratory is needed. in this session, the results of the research project for legislation for the clinical laboratory, which was performed by the Korea Legislation research institute with the cooperation of the KSLm, is going to be presented and the results will be discussed by experts to the public.

SYmPOSium 18: eSCmiD-KSLm SeSSiOn

Precision medicine in infectious diseases

SYmPOSium 19

guidelines on clinical tests for patient care

SYmPOSium 20

role of specialists in transfusion medicinePeople with specialized expertise in the field of transfusion medicine play many roles in the modern hospital setting. this session will look at a variety of activities that are performed by these experts so that patients can receive transfusion support that meets the high standards required nowadays.



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SCIENTIFIC PROGRAM

eDucation WorkSHoPS

eDuCAtiOn WORKSHOP 01

review on potential biotin interference in immunoassaysoverviewBeing available as a “beauty” supplement, biotin has been demonstrated to impact assays that use biotin–streptavidin binding. With biotin use being so pervasive, it is critical that laboratorians and clinicians are aware of biotin interference so that misdiagnosis and inappropriate treatment can be prevented.

expected outcomes1. Know the mechanism of biotin interference in immunoassays utilized with biotin–streptavidin binding.2. recognize immunoassays that are susceptible to biotin interference.3. Plan for preventive actions for biotin interference in clinical laboratories.


atellica solution workflow - Doing more with lessoverviewDr. antonio Buño Soto (mD, PhD, currently the Head of Department at the clinical Pathology Service in Hospital Universitario La Paz at madrid, Spain) will share the experience using the atellica Solution from Siemens Healthineers. His team participated in an early adopter’s program study together with five other sites around europe. in the workflow study, he wanted to outline some of the features that the system can provide. for that purpose the team measured turnaround times, throughput of both analyzers and stat capabilities. results of these studies will be presented in the symposium.

expected outcomesthe existing healthcare scenario of increasing costs and reimbursement pressures combined with the need to reduce expenditure, all challenged by a continuing increase in workload explains why laboratories today must face an increasing pressure to automate their processes. the expected outcome from regarding study will be the use of systems that allows the integration of different laboratory disciplines, permit a decrease in turn-around-times while maintaining the requisite quality of results and requires fewer personnel also, thereby lowering costs.

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cobas pro integrated solutions - Simplicity meets excellenceoverviewWe would like to take you on a journey on our latest innovation. cobas® pro integrated solutions is the next generation of our very successful cobas family for clinical chemistry and immunochemistry testing.

expected outcomesafter this workshop, participants will be able to: experience our latest innovation_cobas® pro integrated solutions.


Significance of full panel assays in syndromic diagnosis for infectious diseasesoverviewthe syndromic diagnosis is an approach of attacking infectious diseases by using a full panel assay for all the suspected pathogens responsible for a certain infectious disease. the importance of using full panel assays in syndromic diagnosis for gastrointestinal infections will be discussed by comparing with conventional diagnostic approaches.

expected outcomesevaluate the validity of the syndromic diagnosis of gastrointestinal infections using full panel assays and understand the needs and advantages of full panel assays in syndromic diagnosis, and discuss thechallenges in modifying current diagnostic approaches and required processes for adopting the syndromic diagnosis.


evaluation of a new isothermal amplification molecular diagnostic method for the diagnosis of influenza infectionoverviewWe evaluated the clinical performances of alerei influenza a&B compared with real-time Pcr, and influenza rapid diagnostic kits. compared to multiplex rt-Pcr, sensitivities of alereifor influenza a were 97.7%. the specificities of alerei were 100.0%.

expected outcomesthe clinical performance resultswere high sensitivity, high specificity and satisfactory with the advantage of a significantly shorter test time than any other currently available molecular assay.



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SCIENTIFIC PROGRAM

eDucation WorkSHoPS


next molecular diagnostics solution with SysmexoverviewDuring the education workshop, Sysmex will introduce new molecular technology working on initiatives promoting personalized healthcare that respond to individual characteristics and primary care that offer testing nearby patients, a variety of technology platforms, such as for genes, cells and proteins, and is pushing forward with technological developments aimed at contributing to personalized medicine, thereby creating new clinical value in addition to expanding its operations in existing in vitro diagnostics (iVD) domains, based on principal disease-derived cells, genes, proteins and other elements present in blood and bodily fluids (liquid biopsy).

expected outcomesUnderstanding next generation liquid biopsy technology by Sysmex in the area of personalized healthcare, which will be helpful to develop companion diagnostic drugs related to drug regimens and liquid biopsy technologies that allow more information to be obtained from the blood.Provide solutions with fewer burdens on patients throughminiaturization oftechnologyaimed at improving operability for achieving primary care strategies.


clinical utility of prostate health index (phi ) for prostate cancer detection and prediction of high risk prostate canceroverview• Beckman Coulter prostate health index (PHI) is a Food and Drug Administration (FDA)-approved test that combines total PSa (tPSa), fPSa and p2PSa.• Several studies demonstrated that PHI significantly improves the predictive accuracy for detection of Pca, and associated with Pca aggressiveness compared to either tPSa or free-to- total PSa ratio (%fPSa) and the implementation of %p2PSa and PHi in clinical practice has the potential to significantly lower the rate of unnecessary prostate biopsies. • Active Surveillance (AS) has emerged as a standard management option for men with very low- risk and low-risk Pca and further studies are required to define that PHi could be incorporated into the follow-up schedule in aS patients.

Standard (Gradation)基本表示（グラデーション）

基本表示（浓淡法）

Monochrome (Solid)モノクロ表示（ソリッド）

单色表示（純色）

Reversed (Monochrome)ネガティブ表示（モノクロ）

负片表示（单色）

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Diagnosis and treatment of latent tuberculosis infectionoverviewto eliminate tuberculosis, diagnosis and treatment of latent tuberculosis infection is essential. recently, to diagnose latent tuberculosis infection, interferon-gamma release assays have been used widely. in this workshop, we will discuss about the methods to diagnose latent tuberculosis infection and treatment regimens for it.

expected outcomes1. Understand the difference between active tB and latent tB infection.2. Understand how to diagnose latent tuberculosis infection.3. Understand the treatment regimens of latent tuberculosis infection.


measurement and clinical application of Hba1c in Japanoverviewexplain the current state of measurement of Hba1c in Japan.efforts and Prospects to improve Hba1c Precision in Japan.

expected outcomesHba1c content of Japan's standardized situation and operation will be shared with participants from different countries with the vision it will spread and be utilized in all countries.


clinical implications of syndromic, rapid, sample-to-answer molecular infectious disease testingoverviewrecent innovative sample-to-answer multiplex Pcr testing (such as Biofirefilmarray) with more rapid, comprehensive, accurate results can enable clinicians to rapidly diagnose certain infections which then can allow more optimal clinical management decisions in antimicrobial treatment, hospital infection control, hospital admission/discharge and ultimately better outcome of patients.

expected outcomesParticipants will review the current literature to discuss clinical implications of syndromic, rapid, sample-to-answer molecular infectious disease testing.



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illumina’s amplicon-based Brca1/Brca2 analysis: Faster and more reliableoverviewanalysis of Brca1 and Brca2 genes for pathogenic mutations is essential for the susceptibility screening and even companion diagnostics of breast cancer and ovarian cancer. traditional analysis based on Pcr and Sanger sequencing has limitations in terms of cost and tat. thus, many clinical laboratories have already turned to ngS solutions regarding Brca1 and Brca2 analysis, which will enable more affordable genetic screening with shorter tat. in this workshop, brief technological introduction for ngS technologies and representative illumina platforms will be provided and analytical performance of amplicon-based ngS assay for Brca1 and Brca2 will be discussed with actual data derived from a clinical practice setting.

expected outcomesthis workshop will provide a basic understanding of ngS technologies and platforms required for comprehensive Brca1 and Brca2 analysis. Participants are expected to obtain a perspective about the overall trend of ngS applications in clinical practice, in particular the analysis of Brca1 and Brca2 genes.

eDucation WorkSHoPS

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DaiLy PrograM _ NovEMbEr 1 (Thu)

10:30-16:00(eng.)

Pre-congress 01:Patient centered laboratory medicine

cosmos Hall (3F)

10:40 -12:00 Women’s health

chair kyung eun Song, kyungpook national university School of medicine, korea

clinical aspect of preeclampsiaJoon-Seok Hong, Department of obstetrics and gynecology, Seoul national University Bundang Hospital, Korea

the clinical implications of amHHoon Kim, Department of obstetrics and gynecology, Seoul national University col-lege of medicine, Korea

13:20 -15:00 Cardiac disease

chair Hwan Sub lim, Seoul clinical laboratories, korea

n-terminal B-type natriuretic peptide in heart failureSeok-min Kang, Division of cardiology, Yonsei University college of medicine, Korea

clinical and economical value of high-sensitivity cardiac troponin t assay in the emergency department chien-chang Lee, national taiwan University Hospital, taiwan

15:20 - 16:00 Oncology

chair gye-cheol kwon, chungnam national university college of medicine, korea

navify tumor board - empowering personalized healthcaremarco antonio Valencia Sanchez, roche Diagnostics asia Pacific, Singapore

08:30-16:30(eng.)

Pre-congress 02: mSACLClinical mass spectrometry workshop by mSACL

art Hall (4F)

Fundamentals of mass spectrometryrobert L. fitzgerald, University of california-San Diego, USa

Drug Screening in real time using lc-mS/mS (without the aid of immunoas-says)Dennis J. Dietzen, Washington University School of medicine, USa



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November 1, Thu

Daily Program _ November 1 (Thu)

thyroglobulin by tandem mass spectrometry: How to do it. When you need it. When you don’t.Daniel t. Holmes, University of British columbia, canada

current status of clinical mass spectrometry in koreaSoo-Youn Lee, Samsung medical center, Sungkyunkwan University School of medicine, Korea

murder and munchausen’s: investigation in spontaneous hypoglycemia using lc-mS/mSDaniel t. Holmes, University of British columbia, canada

Hba1c and variant Hb determination by mass spectrometryDavid Herold, University of california-San Diego, USa

targeted metabolomics of pediatric and maternal-fetal pathologyDennis J. Dietzen, Washington University School of medicine, USa

Setting up a lab for successful implementation of lc-mSDavid Herold, University of california-San Diego, USa

08:00-10:00(kor.)

Symposium 01:the current status of healthcare-associated infection (HAi) and the role of clinical microbiology

Walker Hall 1 (1F)

chairs Wonkeun Song, Hallym university college of medicine, koreami-na kim, university of ulsan college of medicine, korea

Sy01-01 Perspectives of Hais from the korean national healthcare-associated infection surveillance systemYoung Hwa choi, Department of infectious Diseases, ajou University School of medicine, Korea

Sy01-02 the current status of carbapenem-resistant enterobacteriacae in korea: Vicious cycle between acute care hospitals and long term care facilitiesHyungmin Lee, Division of Healthcare associated infection control, Korea centers for Disease control and Prevention, Korea

Sy01-03 impact of rapid surveillance of cPe and preemptive isolation on cPe preven-tion and controltaek Soo Kim, Seoul national University Hospital, Korea

Sy01-04 changing role of clinical microbiology in Hai prevention and controlHyukmin Lee, Yonsei University college of medicine, Korea

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10:00-12:00(kor.)

Symposium 02:inspector workshop of the Korean laboratory accreditation program

Walker Hall 1 (1F)

chairs Dae-Soo moon, chosun university Hospital, koreaJeong yeal ahn, gachon university School of medicine, korea

Sy02-01 Quality control program of point-of-care testingJinsook Lim, chungnam national University Hospital, Korea

Sy02-02 korean laboratory accreditation program (klaP): What laboratory directors and inspection team leaders should know & risk management in clinical laboratoriesWoo-in Lee, Kyung Hee University School of medicine, Korea

Sy02-03 inspection points during laboratory result reporting processSang-guk Lee, Yonsei University college of medicine, Korea

Sy02-04 internal quality control program of viral serological assayHyun Soo Kim, Hallym University college of medicine, Korea

13:00-17:00(kor.)

Symposium 03:education course for laboratory medicine specialist

Walker Hall 1 (1F)

chair myung-geun Shin, chonnam national university medical School, korea

Sy03-01 the recycle bin of a clinical laboratoryJaewoo Song, Yonsei University college of medicine, Korea

Sy03-02 guideline for resident training in diagnostic hematologya-Jin Lee, Daegu catholic University School of medicine, Korea

Sy03-03 current issues in clinical chemistrySang Hoon Song, Seoul national University college of medicine, Korea

Sy03-04 guideline for resident training in clinical chemistryHyung-Doo Park, Sungkyunkwan University School of medicine, Korea

chair chun Hwa ihm, eulji university School of medicine, korea

Sy03-05 current issues in diagnostic immunologyeun Suk Kang, Sungkyunkwan University School of medicine, Korea

Sy03-06 guideline for resident training in diagnostic immunologyYongjung Park, Korea national Health insurance Service ilsan Hospital, Korea



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November 1, Thu

Daily Program _ November 1 (Thu)

Sy03-07 current issues in clinical microbiologyKyoung Un Park, Seoul national University college of medicine, Korea

Sy03-08 guideline for resident training in clinical microbiologyJaehyeon Lee, chonbuk national University medical School, Korea

chair kyung Dong kim, yeungnam university Hospital, korea

Sy03-09 current issues in transfusion medicineSo-Yong Kwon, Korean red cross, Korea

Sy03-10 guideline for resident training in transfusion medicinechun Hwa ihm, eulji University School of medicine, Korea

Sy03-11 current issues in diagnostic geneticsJa Young Seo, gachon University gil medical center, Korea

Sy03-12 guideline for resident training in diagnostic geneticsmin-Jung Kwon, Sungkyunkwan University School of medicine, Korea

chair Dongeun yong, yonsei university college of medicine, korea

Sy03-13 current issues in medical ethicsilhak Lee, Department of medical Humanities and Social Sciences, Yonsei University college of medicine, Korea

Sy03-14 current guideline for specialty qualification examination in laboratory medicinemyung-geun Shin, chonnam national University medical School, Korea

15:00-17:00(kor.)

Symposium 04: mFDS-KSLm Sessionindustry-Academia-Government (iAG) Committee:in vitro diagnostics device registration and modifi-cation for mFDS

Walker Hall 2 (1F)

chairs Won-kyu lee, Division of in Vitro Diagnostic Devices, national institute of Food and Drug Safety evaluation, koreaJe Hoon lee, the catholic university of korea yeouido St. mary’s Hospital, korea

15:00-15:10 Welcome addressHyeon-joo oh, Director general of Department of medical Device evaluation, national institute of food and Drug Safety evaluation, Korea

congratulatory address Junghan Song, ceo of KSLm, Seoul national University college of medicine, Korea

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Sy04-01 Development of a guide for changing the permission based on the negative list system for in vitro diagnosticseun-Jee oh, the catholic University of Korea, college of medicine, Korea

Sy04-02 How to make regulatory approval and market access strategy for in vitro diagnostics deviceHye Kyung chung, Synex, Korea

Sy04-03 understanding of gmP (good manufacturing practices) audits for in vitro diag-nosticsJeong Jin Jo, ministry of food and Drug Safety, Korea

17:00-17:30 Opening Ceremony Walkerhill theatre (B1)

17:30-18:30(eng.)

Plenary Lecture 01 Walkerhill theatre (B1)

chair kyungja Han, the catholic university of korea college of medicine, korea

Blood type and personality – asian mythologyKyou-Sup Han, Seoul national University college of medicine, Korea

18:30-20:00 Welcome Reception Vista Hall 1 (B2)



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November 2, Fri

Daily Program _ November 2 (Fri)

08:00-08:40(eng.)

Keynote Speech 01 Vista Hall 1 (B2)

chair Jang-Soo Suh, kyungpook national university School of medicine, korea

clinical pathologists and taking care of patients in the clinicSeongsoo Jang, University of Ulsan college of medicine, Korea

08:40-10:40(eng.)

Symposium 05:Statistics & ethics for laboratory researches

Vista Hall 1 (B2)

chairs Sunjoo kim, gyeongsang national university School of medicine, koreamina Hur, konkuk university School of medicine, korea

Sy05-01 Publication ethics for authorsSoo Young Kim, Department of family medicine, Hallym University medical college, Korea

Sy05-02 using the r programming language for method validation and medical statisticsDaniel t. Holmes, University of British columbia, canada

Sy05-03 making sense of statistics for laboratory medicineShuji ogino, Harvard medical School, Brigham and Women’s Hospital, Dana-farber cancer institute, Harvard t.H. chan School of Public Health, and Broad institute of mit and Harvard, USa

08:00-10:30(eng.)

Symposium 06:Clinical laboratory reimbursement - Financial aspects of laboratory medicine

Walker Hall 1 (1F)

chairs Hyosoon Park, Sungkyunkwan university School of medicine, koreanisarat opartkiattikul, thai Society of clinical Pathology, thailand

Sy06-01 Financial aspects of laboratory medicine in indiaPraveen Sharma, all india institute of medical Sciences, india

Sy06-02 laboratory test reimbursement policies in Japanese health insurance systems; against cost-cut pressuretaiji furukawa, teikyo University School of medicine, Japan

Sy06-03 clinical laboratory reimbursement in tertiary hospital in indonesianina Susana Dewi, Padjadjaran University Bandung, indonesia

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DaiLy PrograM _ NovEMbEr 2 (Fri)

Sy06-04 Financial aspects of laboratory medicine in mongoliaoyundelger munkhtuvshin ertsuud, mongolian association of the Laboratory medicine, mongolia

Sy06-05 Financial aspects of laboratory medicine in malaysiaLai-meng Looi, University of malaya, malaysia

Sy06-06 clinical laboratory reimbursement – Financial aspects of laboratory medicine in thailandnisarat opartkiattikul, thai Society of clinical Pathology, thailand

Sy06-07 Financial aspects of laboratory medicine in public medical units in Vietnamnguyen minh Ha, nguyen tri Phuong Hospital, Vietnam

Sy06-08 Financial aspect of medical laboratories in myanmarWah Wah aung, ministry of Health and Sports, myanmar

Sy06-09 Health insurance reimbursement system in koreatae Hyun Um, inje University ilsan Paik Hospital, Korea

09:00-10:40(eng.)

Symposium 07:new molecular technologies for personalized medicine

Walker Hall 2 (1F)

chairs Jong-Won kim, Sungkyunkwan university School of medicine, koreaJacky lam, the chinese university of Hong kong, Hong kong

Sy07-01 analysis and clinical applications exosome for liquid biopsy of cancerLei Zheng, nanfang Hospital, china

Sy07-02 application of Beaming technology for circulating tumor Dna detectionmyungshin Kim, the catholic University of Korea college of medicine, Korea

Sy07-03 the current and future of circulating tumor Dna sequencing in precision oncologyYoung Kwang chae, northwestern University feinberg School of medicine, USa

09:00-10:40(eng.)

Oral Presentation 01:Clinical chemistry 1

cosmos Hall (3F)

chairs Sang Hoon Song, Seoul national university college of medicine, koreaSoo-youn lee, Samsung medical center, Sungkyunkwan university School of medicine, korea



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o-18 Sigma metric quality framework-an analyte performance indicator and quality improvement tool Lo man Har VanessaHealth care Department, Six Sigma institute, apleichau, Hong Kong

o-7 evaluation of a multiplex phytosterol assay for inherited lipid storage disorders utilizing gas chromatography-mass spectrometryJoon Hee Lee1,2, Sun-Hee Jun3, Da Young Song1,2, Jong Do Seo1,2, Soo Young moon4, Kyunghoon Lee1,3, Sang Hoon Song1,2, Junghan Song1,3 Department of Laboratory medicine1, Seoul national University college ofmedicine, Seoul, Korea; Department of Laboratory medicine2, Seoul nationalUniversity Hospital, Seoul, Korea; Department of Laboratory medicine3,Seoul national University Bundang Hospital, Seongnam, Korea; Departmentof Laboratory medicine4, Pusan national University Hospital, Busan, Korea

o-8 effect of a mixed meal on serum lipids, insulin resistance and systemic inflam-mation in healthy indian adults and those with hypothyroidismLokesh Kumar Sharma, Deep Dutta, neera SharmaBiochemistry, Pgimer-Dr. ram manohar Lohia Hospital, new Delhi, india

o-9 the incidence of acute kidney disease in hematooncologic patients treated with vancomycinahram Yi1, mina Hur1, Hyeong nyeon Kim2, Hanah Kim1, Hee-Jung chung1, Hee-Won moon1, Yeo-min Yun1 Department of Laboratory medicine1, Konkuk University School ofmedicine, Seoul, Korea; Department of Laboratory medicine2, Samkwangmedical Laboratories, Seoul, Korea

o-10 estimated mean recovery of two low-density lipoprotein cholesterol homoge-neous methods based on non-high-density lipoprotein particle size distributionJaeryuk Kim, Woochang Lee, Sail chun, Won-ki minDepartment of Laboratory medicine, asan medical center, Seoul, Korea

o-11 Study of serum lipid abnormalities in patients with nephrotic syndromeSushil Baral1,2, Kanak Badhur raut1, Bharat Jha1, monaj Sigdel1, Prajwal gyawali1, rojeet Shrestha1

Department of medical Biochemistry1, tU teaching Hospital, Kathmandu, nepal; Department of internal medicine2, Bir Hospital, Kathmandu, nepal

o-12 Plasma isoniazid and rifampicin concentrations and therapeutic drug monitor-ing in treating patients with tuberculosis at a tertiary centrealtaf ahmad mir1,2, Sadhna Sharma2, ajay Kumar Duseja3

Department of Biochemistry1, eSicmc and H, Hyderabad, india; Department of Bio-chemistry2, Department of Hepatology3, Postgraduate institute of medical education and research, chandigarh, india

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o-13 comparison of six hemoglobin a1c measurement methods in hemoglobin e trait, and hemoglobin e trait with alpha-thalassemia 1 traitPanumas Kamkang1, Busadee Pratumvinit1, Kanit reesukumal1, thidarat Suksangp-leng3, Sithikan Hanyongyuth1, Suchada riolueang3, Vip Viprakasit2,3

1Department of clinical Pathology, faculty of medicine Siriraj Hospital, mahidol Univer-sity, Bangkok, thailand; 2Division of Hematology/oncology, Department of Pediatrics, faculty of medicine Siriraj Hospital, mahidol University, Bangkok, thailand; 3Siriraj integrated center of excellence for thalassemia (Siicoe-t), faculty of medicine Siriraj Hospital, mahidol University, Bangkok, thailand

o-14 analysis of protein biomarkers in serum of patients with schizophreniaWei Jiang1,2,3, Kaizheng Wang4, Kezhen Bai5, chao Zhang3

Department of Laboratory medicine1, affiliated Hospital of the University of electronic Science and technology of china & Sichuan Provincial People’s Hospital, chengdu, china; Department of Laboratory medicine2, chengdu tianfu new District People’s Hospital, chengdu, china; School of medicine3, University of electronic Science and technology of china, chengdu, china; 4Department of Laboratory medicine, affiliated Hospital of Southwest medical University, Luzhou, china; 5center for mental Health,affiliated Hospital of Southwest medical University, Luzhou, china

09:30-11:00 Senate meeting art Hall (4F)

10:40-11:00 Break

11:00-12:00(eng.)

Plenary Lecture 02 Vista Hall 1 (B2)

chair gye-cheol kwon, chungnam national university college of medicine, korea

expanding the measurable metabolome: How should we mine the lipidome?Dennis J. Dietzen, Washington University School of medicine, USa

12:00-13:00(eng.)

education Workshop 01 Vista Hall 1 (B2)

chair young Joo cha, chung-ang university Hospital, korea

review on potential biotin interference in immunoassaysHai Young Jung, north asia abbott Diagnostic Division, Korea



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12:00-13:00(eng.)

education Workshop 02 Walker Hall 1 (1F)

chair Dal Sik kim, chonbuk national university medical School, korea

atellica solution workflow - Doing more with lessantonio Buño Soto, La Paz Hospital in madrid, Spain

12:00-13:00(eng.)


chair young Jun Hong, korea cancer center Hospital, korea

cobas pro integrated solutions - Simplicity meets excellenceBenjamin Lilienfeld, roche Diagnostics international, Switzerland

12:00-13:00(eng.)

education Workshop 04:Significance of full panel assays in syndromic diagnosis for infectious diseases

cosmos Hall (3F)

chair Jihyun cho, Wonkwang university School of medicine, korea

eW04-01 Study of full panel assays for syndromic approach of diagnosisKyoung Ho roh, Seegene medical foundation, Korea

eW04-02 evaluation of allplex gi assays in detecting pathogens causing antibiotic-associated diarrhea (aaD) in stool specimens collected from korean nation-wide veterans hospitaleunsin Bae, Veterans Healthcare Service (VHS) medical center, Korea

12:00-13:00(eng.)

education Workshop 05 art Hall (4F)

chair chang kyu lee, korea university college of medicine, korea

evaluation of new isothermal amplification molecular diagnostic method for the diagnosis of influenza infectionchea-Seung Lim, Korea University guro Hospital, Korea

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13:00-14:40(eng.)

Symposium 08:Practical aspects of laboratory management iV; Laboratory information System (LiS) & information Communication technology (iCt)

Vista Hall 1 (B2)

chairs ile-kyu Park, Hanyang university medical center, guri Hospital, koreaDaniel t. Holmes, university of British columbia, canada

Sy08-01 Basic principle of liSJe Hoon Lee, the catholic University of Korea Yeouido St. mary’s Hospital, Korea

Sy08-02 using the r statistical programming language for quality improvement and monitoringJanet Simons, St. Paul’s Hospital, canada

Sy08-03 maximizing the value of test results with ictWon-Ki min, University of Ulsan college of medicine, Korea

Sy08-04 middle ware applications and ictHyung Hoi Kim, Pusan national University Hospital, Korea

13:00-14:40(eng.)

Symposium 09:education track i

Walker Hall 1 (1F)

chairs Hee Jung kang, Hallym university college of medicine, koreanamhee ryoo, keimyung university School of medicine, korea

Sy09-01 updates on laboratory diagnosis of HiV infectionYounhee Park, Yonsei University college of medicine, Korea

Sy09-02 application of rapid molecular diagnostic method for tuberculosischang Ki Kim, Seoul clinical Laboratories, Korea

Sy09-03 microbial laboratory tests using matrix assisted laser desorption ionization-time of flight mass spectrometry (malDi-toF mS)Jeong Su Park, Seoul national University Bundang Hospital, Korea

Sy09-04 clinical principles and applications of molecular genetic testingSeung-tae Lee, Yonsei University college of medicine, Korea



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13:00-14:40(eng.)

Symposium 10:Genomics of human leukocyte antigen (HLA) inthe era of next generation sequencing (nGS)

Walker Hall 2 (1F)

chairs eun Suk kang, Sungkyunkwan university School of medicine, koreaDong Hee Whang, inje university college of medicine, korea

Sy10-01 the 17th international Hla and immunogenetics workshop: advances in ngS for studying Hla Steven J. mack, the UcSf School of medicine, USa

Sy10-02 Hla genomics in the field of disease associationKatsushi tokunaga, University of tokyo graduate School of medicine, Japan

Sy10-03 role of Hla-DP in HBV vaccine responseSoie chung, Seoul national University Hospital Healthcare System gangnam center, Korea

13:00-14:40(eng.)

Oral Presentation 02:Clinical microbiology

cosmos Hall (3F)

chairs young uh, yonsei university Wonju college of medicine, koreaSunHwa lee, Seegene medical Foundation, korea

o-19 evaluation of the lower critical concentration for moxifloxacin dst based on lj media recently revised by WHoSoyoun Shin, Byungchul ahn, Seungmo Kim, Soyul Kim, Jongmyun Songaboratory medicine center, the Korean institute of tuberculosis, osong, Korea

o-20 evaluation of linezolid-resistance from vancomycin-resistant enterococcus faecium under pressure of linezolid treatment in a tertiary-care hospital Kuenyoul Park, Sookja Park, Jeonghyun chang, Heungsup Sung, mi-na KimDepartment of Laboratory medicine, University of Ulsan college of medicine and asan medical center, Seoul, Korea

o-21 analysis of the possibility of sputum aFB grading using a classification model based on deep learning taeyoung Kim1, Hyunwoo Park1, myungjin choi1, Soyoun Shin2

inSpace co., Ltd.1, Daejeon, Korea; the Korean institute of tuberculosis2, osong, Korea

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o-22 Determining the genes involved in the evolution of carbapenem resistance in klebsiella pneumoniaenaina a. Pinto1,2, muyoung Lee3, Hyunsook Lee1,2, roshan D’Souza4, insuk Lee3, Don-geun Yong1,2

Department of Laboratory medicine and research institute of Bacterial resistance1, Yonsei University college of medicine, Seoul, Korea; Brain Korea 21 PLUS Project for medical Science2, Yonsei University, Seoul, Korea; Department of Biotechnology, col-lege of Life Science and Biotechnology3, Yonsei University, Seoul, Korea; J. craig Venter institute4, rockville, maryland, USa

o-23 risk factor analysis for candidemia caused by PDr1-mutant candida glabrata and its clinical outcomes eun Jeong Won1, Jong Hee Shin2, min Ji choi2, Seung a Byun2, Soo Hyun Kim2, Yeon-Joon Park3, mi-na Kim4, Young Uh5, Jaehyeon Lee6, Hye Soo Lee6, Sun Hoe Koo7

Department of Parasitology and tropical medicine1, chonnam national University medical School, Hwasun, Korea; Department of Laboratory medicine2, chonnam national University medical School, gwangju, Korea; Department of Laboratory medi-cine3, the catholic University of Korea college of medicine, Seoul, Korea; Department of Laboratory medicine4, University of Ulsan college of medicine and asan medical center, Seoul, Korea; Department of Laboratory medicine5, Yonsei University Wonju college of medicine, Wonju, Korea; Department of Laboratory medicine6, chonbuk national University medical School and chonbuk national University Hospital Branch of national culture collection for Pathogens, Jeonju, Korea; Department of Laboratory medicine7, college of medicine, chungnam national University, Daejeon, Korea

o-24 establishment of a fecal microbiota bank and fecal microbiota transplantation at a korean university affiliated hospitalHyun Soo Seo1,2, Yeon-Hee Kim1,2, Hyung Sun chin1,2, Hye Su moon1,2, chul Soon Park1,2, Jung-Hyun Byun1, Wonjun Kim2, Dongeun Yong1,2

Department of Laboratory medicine and research institute of Bacterial resistance1, Yonsei University college of medicine, Seoul, Korea; microbiotix coorporation2, Seoul, Korea



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o-25 evaluation of mock communities for assessing the characteristics of ngS us-ing illumina miSeq for microbiome analysis Younjee Hwang1,2, Ju Yeong Kim2,3, Se il Kim4,5, Ji Yeon Sung1,6, Hye Su moon1, tai-Soon Yong3, Dongeun Yong1,2; Department of Laboratory medicine and research institute of Bacterial resistance1, Yonsei University college of medicine, Seoul, Korea; Brain Korea 21 PLUS Project for medical Science2, Yonsei University college of medicine, Seoul, Korea; Department of environmental medical Biology, institute of tropical medicine, and arthropods of med-ical importance resource Bank3, Yonsei University college of medicine, Seoul, Korea; Division of chemical and medical metrology4, center for Bioanalysis, Korea research institute of Standards and Science, Daejeon, Korea; convergent research center for emerging Virus infection5, Korea research institute of chemical technology, Daejeon, Korea; roche Diagnostics6, Seoul, Korea

o-26 clinical utility of fecal calprotectin and neutrophil gelatinase-associated lipo-calin in clostridium difficile infectionsJoowon Yi, Hee-Won moon, Hanah Kim, Jeong Hee-Jeong, mina Hur, Yeo-min YunDepartment of Laboratory medicine, Konkuk University School of medicine, Seoul, Korea

o-27 Human herpes virus type 6 and other viruses causing aseptic meningitis in children in Sudannada a. abdelrahim1, nahla a. mohammed2, magnus evander2, clas ahlm3, imad m. fadl-elmula4

Unit of Pharmaceutical microbiology & research, Department of Pharmacy1, nile college, Khartoum, Sudan; Department of clinical microbiology, Division of Virology2, Umea Hospital University, Umea, Sweden; Department of clinical microbiology, Divi-sion of infectious Diseases3, Umea Hospital University, Umea, Sweden; Department ofPathology & clinical genetics4, faculty of medicine, al-neelain University, Khartoum, Sudan

13:00-14:40(eng.)

Oral Presentation 03:General laboratory medicine & transfusion medicine

art Hall (4F)

chairs So-yong kwon, korean red cross, koreaSae yun Baik, Seoul clinical laboratories, korea

o-32 Benefits of automated cross-matching using vision max: a multidimensional analysis Hee-Jung chung, mina Hur, Hyunkyung Lee, Sang gyeu choi, Hanah Kim, Hee-Won moon, Yeo-min YunDepartment of Laboratory medicine, Konkuk University School of medicine, Seoul, Korea

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o-33 understanding thrombocytopenia: role of microrna in neonatal and adult megakaryopoiesisravi Kumar gutti, Sanjeev raghuwanshiDepartment of Biochemistry, University of Hyderabad, Hyderabad, india

o-48 Successful development of real-time display of the ongoing phases of labora-tory tests and expert comments by laboratory physician on the computerized order communication systemSollip Kim1, tae Hyun Um1, chong rae cho1, Dong Wun Shin2

Department of Laboratory medicine1,inje University ilsan Paik Hospital, goyang, Korea; emergency medicine2, inje University, ilsan Paik Hospital, goyang, Korea

o-49 new strategy of nationwide sentinel surveillance for respiratory virus infectionSeungman Park, Ye-Jin oh, mi-na Lee, Hyunmi choi, Yoolim oh, eun-Hee LeeDepartment of Laboratory medicine, green cross Laboratories, goyang, Korea

o-50 Performance evaluation of the uf-5000 for body fluid analysis mo Sae Koo, Sun Hoe Koo, gye cheol Kwon, Seon Young Kim, Jinsook LimDepartment of Laboratory medicine, chungnam national University collegeof medicine, Daejeon, Korea

o-51 a low-cost iot diagnosis platform for monitoring pregnancy status in a re-source-limited settingJun Hyeok Hong, moo Kyoung You, gyeong Jun Jin, m. Jalal Uddin, Joon Sub ShimDepartment of electronics convergence engineering, Kwangwoon University, Seoul, Korea

o-52 Development of a point-of-care diagnostic test for the detection of mycobacte-rium tuberculosis directly from patient blood samplesamit Singh, anil Kumar gupta, Sarman SinghDepartment of Laboratory medicine, all india institute of medical Sciences, new Delhi, india

o-53 comparison of the efficacy of the malaria Pf/Pv test and star diagnostic plus® test to diagnose falciparum and vivax malariaYusra Yusra1, maria ma Djuang2

Department of clinical Pathology1, faculty of medicine, Universitas indonesia, Jakarta, indonesia; Department of clinical Pathology2, Betun Border Buffer general Hospital, malaka, east nusa tenggara, indonesia

14:40-15:00 Break



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15:00-17:00(eng.)

Symposium 11:Accreditation system for the clinical laboratory

Vista Hall 1 (B2)

chairs Woo-in lee, kyung Hee university School of medicine, koreayoung kyung lee, Hallym university college of medicine, korea

Sy11-01 accreditation for next generation sequencingryan robetorye, mayo clinic, USa

Sy11-02 accreditation as a driver of quality improvement and patient-centerednesscarsten engel, Danish institute for Quality and accreditation in Healthcare (iKaS), Denmark

Sy11-03 lmF accreditation & iSo 15189Wee gyo Lee, ajou University School of medicine, Korea

15:00-16:40(eng.)

Symposium 12:education track 2

Walker Hall 1 (1F)

chairs Seok lae chae, Dongguk university college of medicine, koreanam yong lee, Sungkyunkwan university School of medicine, korea

Sy12-01 interpretation of quality control in clinical chemistryKyunghoon Lee, Seoul national University college of medicine, Korea

Sy12-02 molecular genetic tests of hematologic malignancymi-ae Jang, Soonchunhyang University college of medicine, Korea

Sy12-03 aBo discrepancies and rhD variantsDuck cho, Sungkyunkwan University School of medicine, Korea

Sy12-04 evolution of antimicrobial resistance in neisseria gonorrhoeaeHyukmin Lee, Yonsei University college of medicine, Korea

15:00-16:40(eng.)

Symposium 13: AACC-KSLm Select Sessionemerging clinical applications for circulating DnA analysis

Walker Hall 2 (1F)

chairs kyung-a lee, yonsei university college of medicine, korealei Zheng, nanfang Hospital, china

Sy13-01 cancer screening by circulating tumor Dna analysis is becoming a clinical realityJacky Lam, the chinese University of Hong Kong, Hong Kong

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Sy13-02 graft-derived cell-free Dna – a promising noninvasive marker for detection of rejection and graft injury after solid organ transplantationmichael oellerich, george-august University, germany

Sy13-03 the external quality assessment (eQa) program for circulating tumor Dna analysis: Status quo and prospectsWoochang Lee, University of Ulsan college of medicine, Korea

15:00-16:40(eng.)

Oral Presentation 04:Diagnostic genetics 1 & Diagnostic hematology

cosmos Hall (3F)

chairs you kyoung lee, Soonchunhyang university Bucheon Hospital, koreaJi-young Park, Hallym university college of medicine, korea

o-34 novel platform for cell-free nucleic acids isolation from liquid biopsies of can-cer patientschoong eun Jin1,2, Bonhan Koo1,2, tae Yoon Lee3, Kyudong Han4, Seok-Byung Lim5, in Ja Park5, Yong Shin1,2

Department of convergence medicine1, asan medical center and University of Ulsan college of medicine, Seoul, Korea, Biomedical engineering research center2, asan in-stitute of Life Sciences, asan medical center, Seoul, Korea, Department of technology education and Department of Biomedical engineering3, chungnam national Universi-ty, Daejeon, Korea, Department of nanobimedical Science & BK21 PLUS nBm global research center for regenerative medicine4, Dankook University, cheonan, Korea, Department of colon & rectal Surgery5, asan medical center and University of Ulsan college of medicine, Seoul, Korea

o-35 rna sequencing-based whole transcriptome analysis provided accurate detec-tion of all fusion transcripts in hematological malignancyJun Hyung Lee1, Hyun-Jung choi1, Seung-Jung Kee1, Soo-Hyun Kim1, Jong-Hee Shin1, Soon-Pal Suh1, myung-geun Shin1,2 Department of Laboratory medicine1, chonnam national University medical School and chonnam national University, Hwasun Hospital, Hwasun, Korea; Brain Korea 21 Project2, center for Biomedical Human resources, chonnam national University, gwangju, Korea

o-36 a biomedical knowledgebase and a web-based tool for the interpretation of genetic variants Zehwan Kim, Ju Han KimSeoul national University Biomedical informatics (SnUBi), Division of Biomedical informatics, Seoul national University college of medicine, Seoul, Korea



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o-37 ganseq: an easy-to-use sanger sequencing analysis software built with open source bioinformatics libraries Young-gon Kim, Seo Jin Park, chi Hyun cho, eun ah chang, myung Hyun namDepartment of Laboratory medicine, Korea University medical center, Seoul, Korea

o-1 usefulness of hidden parameters of an automated hematology analyzer for distinguishing myelodysplastic syndromeseunyup Lee, Kibum Jeon, Jiwon Lee, Jee-Soo Lee, miyoung Kim, Han-Sung Kim, Hee Jung Kang, Young Kyung LeeDepartment of Laboratory medicine, Hallym University Sacred Heart Hospital, anyang, Korea

o-2 a neuraminidase inhibitor and platelet countsSun-Young Ko1, Young-gon Kim1, Sung Woo Lee2

Department of Laboratory medicine1, Korea University college of medicine, Seoul, Korea; Department of emergency medicine2, Korea University college of medicine, Seoul, Korea

o-3 Bone marrow recovery of hematopoietic stem cells and of the microenviron-ment after chemotherapy for childhood acute lymphoblastic leukemiaSang Hyuk Park1, mee Jeong Lee2, chan-Jeoung Park3, Seongsoo Jang3, eul-Ju Seo3, Ho-Joon im4, Jong-Jin Seo4

Department of Laboratory medicine1, University of Ulsan college of medicine, Ulsan University Hospital, Ulsan, Korea; Department of Pediatrics2, college of medicine, Dankook University, cheonan, Korea; Department of Laboratory medicine3, University of Ulsan college of medicine and asan medical center, Seoul, Korea; Department ofPediatrics4, University of Ulsan college of medicine and asan medical center, Seoul, Korea

o-4 clinical application of next-generation sequencing to the diagnostic workup of patients with acute myeloid leukemia and myelodysplastic syndromemin Young Lee, Young-Uk cho, chan-Jeoung Park, Seongsoo Jang, ari ahnDepartment of Laboratory medicine, asan medical center, University of Ulsan college of medicine, Seoul, Korea

o-5 comprehensive analysis of genetic variations in patients with acute lympho-blastic leukemiaJihye Ha1, Borahm Kim1, Saeam Shin4, Jieun Jang3, Soo Jeong Kim3, Seung-tae Lee1, June-Won cheong3, chuhl Joo Lyu2, Yoo Hong min3, Jong rak choi1

Department of Laboratory medicine1, Yonsei University college of medicine, Seoul, Korea; Department of Pediatrics2, Yonsei University college of medicine, Seoul, Korea; Department of internal medicine3, Yonsei University college of medicine, Seoul, Korea; Department of Laboratory medicine4, Hallym University college of medicine, gangnam Sacred Heart Hospital, Seoul, Korea

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15:00-16:40(eng.)

Oral Presentation 05:Clinical chemistry 2 & Diagnostic immunology

art Hall (4F)

chairs Seung-Jung kee, chonnam national university medical School, koreaHyung-Doo Park, Sungkyunkwan university School of medicine, korea

o-15 circulating biologically active adrenomedullin (bio-aDm) and proenkephalin predict organ dysfunction mortality in patients with sepsisHanah Kim1, mina Hur1, Joachim Struck2, andreas Bergmann2, and Salvatore Di Somma3; 1Department of Laboratory medicine, Konkuk University School of medicine, Seoul, Korea; 2Sphingotec gmbH, Hennigsdorf, germany; 3Departments of medical-Surgery Sciences and translational medicine, School of medicine and Psychology, ‘Sapienza’ University, Sant’ andrea Hospital, rome, italy

o-16 evaluation of the analytical performance and establishment of a reference interval for the axis-shield clinical chemistry heparin binding protein assaySumi Yoon, mina Hur, Hanah Kim, Hee-Jung chung, Hee-Won moon, Yeo-min YunDepartment of Laboratory medicine, Konkuk University School of medicine, Seoul, Korea

o-17 gap between actual Qc and report Qc: Difference in number of results and impact on rejection rateSoo Young moon1, Sun min Lee2, Hyung Hoi Kim1

Department of Laboratory medicine1, Pusan national University Hospital, Busan; Department of Laboratory medicine2, Pusan national University Yangsan Hospital, Yangsan, Korea

o-6 Biochemical and molecular genetic characteristics in korean patients with 17α-hydroxylase/17,20-lyase deficiencyJongwon oh, Soo-Youn Lee, Hyung-Doo ParkDepartment of Laboratory of medicine & genetics1, Samsung medicalcenter, Sungkyunkwan University School of medicine, Seoul, Korea

o-28 evaluation of FlowDSa-Xm for detecting donor-specific Hla antibodiesJong-mi Lee, aeran choi, Hoon Seok Kim, eun-Jee oh Department of Laboratory medicine, Seoul St. mary’s Hospital, college of medicine, the catholic University of Korea, Seoul, Korea

o-29 application of enhanced liver fibrosis and glycosylation isomer of mac-2 bind-ing protein in non-invasive clinical algorithms for liver fibrosismikyoung Park, mina Hur, Hanah Kim, Hee-Jung Jung, Hee-Won moon, Yeo-min YunDepartment of Laboratory medicine, Konkuk University School of medicine, Seoul, Korea



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o-30 comparison of the results between eliSpot and eliSa interferon gamma releasing assays of workers in the independent laboratoryDo-cic mihn, Soo-Hyun KimDiagnostic immunology, Seegene medical foundation, Seoul, Korea

o-31 uses of paired serum samples along with clinical manifestation in diagnosis of toxoplasma gondii infection Khalid Hajissa1,2, Zeehaida mohamed1, Padmaloseni thangarajah1, muhammad amiruddin abdullah1

Department of microbiology and Parasitology1, School of medical Sciences, Universiti Sains malaysia, Kubang Kerian, malaysia; Department of Zoology2, faculty of Science and technology, omdurman islamic University, omdurman, Sudan

17:00-17:40(eng.)


chair Jeong-Ho kim, yonsei university college of medicine, korea

Strategies to optimize medical laboratory for patient care in the era of universal coverageLia g Partakusuma, national cardiovascular centre Harapan Kita, indonesia

17:00-18:00(eng.)

education Workshop 06:next molecular diagnostics solution in Sysmex

Walker Hall 2 (1F)

chair yonggoo kim, the catholic university of korea college of medicine, korea

Highly sensitive liquid biopsy platformstoshiyuki Sato, Strategic technology Planning Division, Sysmex r&D, Japan

18:00-20:00 Banquet Walkerhill theatre (B1)



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Daily Program _ November 3 (Sat)

08:00-08:40(eng.)


chair Won-ki min, university of ulsan college of medicine, korea

Bioactive lipids in laboratory medicineYutaka Yatomi, the University of tokyo graduate School of medicine, Japan

09:00-10:40(eng.)

Symposium 14: CLSi-KSLm SessionCustomer focused documents of CLSi

Vista Hall 1 (B2)

chairs Hwan Sub lim, Seoul clinical laboratories, koreacarl D. mottram, mayo clinic college of medicine, uSa

Sy14-01 clSi document QmS19-customer focus in a quality management systemcarl D. mottram, mayo clinic college of medicine, USa

Sy14-02 clSi document gP45-Studies to evaluate patient outcomesJames H. nichols, Vanderbilt University School of medicine, USa

Sy14-03 Developing and managing a medical laboratory (test) utilization management programSollip Kim, inje University ilsan Paik Hospital, Korea

09:00-10:40(eng.)

Symposium 15:Recent trends in clinical chemistry for optimal patients care

Walker Hall 1 (1F)

chairs Hi Jeong kwon, the catholic university of korea college of medicine, koreaDavid Herold, university of california-San Diego, uSa

Sy15-01 critical levels of serum 25-Hydroxyvitamin D for metabolic bone diseaseHoward morris, University of South australia, australia

Sy15-02 cannabinoids in california-approach to assessing driving under the influencerobert L. fitzgerald, University of california-San Diego, USa

Sy15-03 optiumum utilization of automated urine microscopyJeong-Ho Kim, Yonsei University college of medicine, Korea

Sy15-04 Screening of chitotriosidase: its significance in detection and differential diag-nosis of inherited metabolic diseasesYoon Shin-Podskarbi, Ludwig maximilian University of munich, germany

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DaiLy PrograM _ NovEMbEr 3 (Sat)

09:00-10:40(eng.)

Symposium 16:updates in laboratory hematology

Walker Hall 2 (1F)

chairs chan-Jeoung Park, university of ulsan college of medicine, koreaJin-yeong Han, Dong-a university college of medicine, korea

Sy16-01 Flow cytometry for acute leukemia diagnosis and classificationchan-Jeoung Park, University of Ulsan college of medicine, Korea

Sy16-02 clot wave form analysis, laboratory monitoring of bleeding in hemophiliamidori Shima, nara medical University, Japan

Sy16-03 update on the pathogenesis and laboratory diagnosis of thromboticthrombocytopenic purpuraross i. Baker, murdoch University, australia

09:00-10:40(kor.)

Symposium 17: KCDC-KSLm SessionLegislation for diagnostic tests: national regulation or supports

cosmos Hall (3F)

chairs Won keun Seong, center for laboratory control of infectious Diseases, centers for Disease control & Prevention, koreaJunghan Song, Seoul national university college of medicine, korea

Sy17-01 Background and necessity of enactment of the act on laboratory testing in health and medical fieldSeung-Hee Seo, Korea centers for Disease control and Prevention, Korea

Sy17-02 introduction of current status of legislation in other countriestae Hyun Um, inje University ilsan Paik Hospital, Korea

Sy17-03 a study on the enactment of the “act on tests, diagnostic examinations, etc. for health and medical services”Sejeong Yi, Korea Legislation research institute, Korea

09:00-10:40(eng.)

Oral Presentation 06:Diagnostic genetics 2

art Hall (4F)

chairs eul-Ju Seo, university of ulsan college of medicine, koreaSun-young kong, national cancer center, korea



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o-38 Plasma rna profiling in patients with colorectal cancer using a nanoString-based platformHin fung tsang1,2, Yin Kwan evelyn Wong2, chi Shing William cho4, Sze chuen cesar Wong2,3

Department of clinical Laboratory and Pathology1, Hong Kong adventist Hospital, Hong Kong Special administrative region; Department of Health technology and informatics2, faculty of Health and Social Sciences, the Hong Kong Polytechnic Uni-versity, Hong Kong Special administrative region; Department of Pathology3, Queen elizabeth Hospital, Hong Kong Special administrative region; Department of clinical oncology4, Queen elizabeth Hospital, Hong Kong Special administrative region

o-39 genetic spectrum of idiopathic dilated cardiomyopathy unveiled by next-gener-ation sequencing in a large cohort of koreaHyunjung gu1, man Jin Kim1, Dahae Yang1, minyoung Kim1, Sung im cho1, Dae-Won Sohn2, eun-Jung Bae3, Sung Sup Park1, moon-Woo Seong1

Department of Laboratory medicine1, Seoul national University Hospital,Seoul, Korea; cardiovascular center, Department of internal medicine2, Seoul national University Hospital, Seoul, Korea; Department of Pediatrics3, Seoul national University children’s Hospital, Seoul, Korea

o-40 application of next generation sequencing of gene panels for patients with genetic skin disordersJin Ju Kim1, Borahm Kim1, Seung-tae Lee1, min geol Lee2,Sang Ho oh2, Jong rak choi1

Department of Laboratory medicine1, Yonsei University college of medicine, Seoul, Ko-rea; Department of Dermatology2, Yonsei University college of medicine, Seoul, Korea

o-41 Strategies to enhance clinical and diagnostic utility of targeted panel sequenc-ing in korean hearing loss patientsJohn Hoon rim1,2,4, Jinsei Jung3, Heon Yung gee1,2, Borahm Kim4, Seung-tae Lee4, Jae Young choi3, Jong rak choi4

Department of Pharmacology1, Yonsei University college of medicine, Seoul, Korea; Department of medicine, Physician-Scientist Program2, Yonsei University graduate School of medicine, Seoul, Korea; Department of otorhinolaryngology3, Severance Hospital, Yonsei University college of medicine, Seoul, Korea; Department of Labora-tory medicine4, Severance Hospital, Yonsei University college of medicine, Seoul, Korea

o-42 Diagnostic and clinical implications of a targeted ngS panel in eye disordersYu Jin Park1, Borahm Kim1, Jinu Han2, eung Kweon Kim2, Seung-tae Lee1, Jong rak choi1

Department of Laboratory medicine1, Yonsei University college of medicine, Seoul, Korea; Department of ophthalmology, corneal Dystrophy research institute2, Yonsei University college of medicine, Seoul, Korea

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o-43 multiplex bio-optical sensor for diagnosis of emerging infectious diseases in human respiratory specimensBonhan Koo1, Ki-Ho Hong2, choong eun Jin1, Ji Yeun Kim3, Sung-Han Kim3, Yong Shin1

Department of convergence medicine1, University of Ulsan college of medicine, asan institute of Life Sciences and asan medical center, Seoul, Korea; Department of Laboratory medicine2, Seoul medical center, Seoul, Korea; Department of infectious Diseases3, University of Ulsan college of medicine and asan medical center, Seoul, Korea

o-44 Performance of noninvasive prenatal test from 14,352 singleton pregnancies in korean populationJa-Hyun Jang1,2, Dasom Kim1, minjung Kim1, Sunghee Bang1, chang-Seok Ki1, eun-Hae cho1

research Department1, gc genome, goyang; Department of Human genetics2, gc Labs, goyang, Korea

o-45 association of SnaP-25 (rs3746544) and Dmt1 (rs224589) polymorphism with a body lead burden in occupationally lead (Pb)-exposed individuals of rajasthan, indiaPrasenjit mitra, Shailja Sharma, PVSn Kiran Kumar, raghumoy ghosh, Praveen SharmaDepartment of Biochemistry, all india institute of medical Sciences, Jodhpur, india

o-46 evaluation of candidate SnPs in tmPrSS6 and tF as potential diagnostic markers of anemia in pregnant Filipino womenVanessa Joy timoteo1, Leslie michelle Dalmacio2, mario capanzana3 institute of Biomedical Sciences1, academia Sinica, taiwan international graduate Program-molecular medicine, taipei city, taiwan; Department of Biochemistry and molecular Biology2, college of medicine, University of the Philippines, manila, Philip-pines; Department of Science and technology3, food and nutrition research institute, taguig city, metro manila, Philippines

10:40-11:00 Break

11:00-12:00(eng.)

Plenary Lecture 03 Vista Hall 1 (B2)

chair kyungwon lee, yonsei university college of medicine, korea

the fight against antimicrobial resistance: are we doing right?Jesús rodríguez Baño, University of Sevilla, Spain



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12:00-13:00(eng.)

education Workshop 07 Vista Hall 1 (B2)

chair rojin Park, Soonchunhyang university college of medicine, korea

clinical utility of prostate health index (phi ) for prostate cancer detection and prediction of high risk prostate cancerJeong Hyun Kim, Kangwon national University Hospital, Korea

12:00-13:00(eng.)


chair Hyon-Suk kim, yonsei university college of medicine, korea

Diagnosis and treatment of latent tuberculosis infectionYoung ae Kang, Department of internal medicine, Yonsei University college ofmedicine, Korea

12:00-13:00(eng.)


chair minjeong Park, Hallym university college of medicine, korea

measurement and clinical application of Hba1c in Japanasako Sato, tokyo Women’s medical University, Japan

12:00-13:00(eng.)

education Workshop 10 cosmos Hall (3F)

chair Jae-Seok kim, Hallym university college of medicine, korea

clinical implications of syndromic, rapid, sample-to-answer molecularinfectious disease testinggeehay Hong, biomerieux Korea co., Ltd, Korea

12:00-13:00(eng.)

education Workshop 11 art Hall (4F)

chair Jong rak choi, yonsei university college of medicine, korea

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illumina’s amplicon-based Brca1/Brca2 analysis: Faster and more reliableWoochang Lee, University of Ulsan college of medicine, Korea

13:00-13:40(eng.)


chair chulhun l. chang, Pusan national university School of medicine, korea

integrative analyses of microbiota, immunity & environment can transform (laboratory) medicineShuji ogino, Harvard medical School, Brigham and Women’s Hospital, Dana-farber cancer institute, Harvard t.H. chan School of Public Health, and Broad institute of mit and Harvard, USa

14:00-15:30(eng.)

Symposium 18: eSCmiD-KSLm SessionPrecision medicine in infectious diseases

Vista Hall 1 (B2)

chairs Seok Hoon Jeong, yonsei university college of medicine, koreaJesús rodríguez Baño, university of Sevilla, Spain

Sy18-01 the coming era of precision medicine in infectious diseasesJesús rodríguez Baño, University of Sevilla, Spain

Sy18-02 next generation sequencing in routine clinical microbiologyJohn rossen, University of groningen, the netherlands

Sy18-03 multiplex identification of major sepsis-causing pathogens from the plasma of infected bloodYeun-Jun chung, Department of microbiology, the catholic University of Korea college of medicine, Korea

14:00-15:40(eng.)

Symposium 19:Guidelines on clinical tests for patient care

Walker Hall 1 (1F)

chairs Sail chun, university of ulsan college of medicine, koreaPhilippe gillery, university of reims champagne-ardenne, France



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Sy19-01 chronic renal failure biomarkergraham Jones, St Vincent’s Hospital, australia

Sy19-02 Biomarkers of diabetesPhilippe gillery, University of reims champagne-ardenne, france

Sy19-03 guideline for protein electrophoresis tests for patient careHelen martin, Sa Pathology, australia

Sy19-04 next generation sequencing-based gene panel and exome testingchang-Seok Ki, green cross genome, Korea

14:00-15:30(eng.)

Symposium 20:Role of specialists in transfusion medicine

Walker Hall 2 (1F)

chairs Hyun ok kim, yonsei university college of medicine, koreayoung ae lim, ajou university School of medicine, korea

Sy20-01 the role of the transfusion practitioner as a specialist in transfusion medicinerachel moss, great ormond Street Hospital for children nHS foundation trust, UK

Sy20-02 Support of blood banks for surgeryDavid roxby, flinders medical centre, australia

Sy20-03 a consultant for cliniciansSejong chun, chonnam national University medical School, Korea

15:40-16:00 KSLm General Assembly

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