PROGRAM3rd AUSTRIAN BIOMARKER SYMPOSIUMEarly Diagnostics

08:00 - 08:45 Registration & Coffee

08:45 - 09:00 Welcome by AIT Austrian Institute of Technology

09:00 - 12:40 Session 1: Personalized Medicine and Early Diagnosis (Chair Wendy Alderton)

09:00 - 09:20 Epigenetic biomarker development for precision medicine. Christoph Bock, Center of Molecular Medicine (CEMM), Austria

09:20 - 09:45 Advances in the Early Detection of Ovarian Cancer. Wendy Alderton, Abcodia, United Kingdom

09:45 - 10:05 Gender Medicine in Diabetes and Cancer. Alexandra Kautzky-Willer, Medical University of Vienna, Austria

10:05 - 10:25 A Novel Sample Preparation Concept for Sepsis Diagnostics: Efficient Cell Type-Specific Lysis by Electric Fields using High-K Dielectric Electrode Passivation. Klemens Wassermann, Austrian Institute of Technology, Austria

10:25 - 10:45 Liquid Biopsy a new tool in the era of personalized medicine. Luca Quagliata, University Hospital Basel, Switzerland

10:45 - 11:20 Coffee

11:20 - 11:40 Identification of Stem Cells marker genes using an unbiased data-driven approach. Frank Staubli, Nebion, Switzerland

11:40 - 12:00 Are blood metabolites the key for early diagnosis in pulmonary hypertension? Natalie Bordag, CBmed GmbH, Austria

12:00 - 12:20 Immortal human primary like cells: relevant and standardizable model systems. Johannes Grillari, EverCyte, Austria

12:20 - 12:40 Diagnosis of Prostate Cancer using microRNAs from Urinary Exosomes. Anne Karin Rasmussen, Exiqon A/S, Denmark

12:40 - 14:00 Lunch

13:30 - 14:30 Coffee & Poster Presentation

14:30 - 17:40 Session 2: Big Data & Systems Biology (Chair Reinhard Schneider)

14:30 - 15:15 Key Note Lecture 1: Big data and mathematical modeling in biomarker discovery. Parag Mallick, Stanford University, USA

15:15 - 15:35 Molecular genetic testing and the future of clinical genomics. Angelo Nuzzo, Platomics, Austria

15:35 - 16:00 Big Data and Computation Platform for the Detection of Biomarker Signatures as Part of the Luxembourg Parkinson’s Disease Cohort. Reinhard Schneider, University of Luxembourg, Luxembourg

16:00 - 16:20 Coffee

16:20 - 16:40 Diagnosing lung cancer: Selection of diagnostic features from genome wide DNA methylation data and validation in cell-free blood. Klemens Vierlinger, Austrian Institute of Technology, Austria

16:40 - 17:00 Patient-specific mathematical models of signal transduction pathways as robust biomarkers for the stratification of cancer patients. Walter Kolch, System Biology Irland & Conway Institute, University College Dublin, Ireland

17:00 - 17:20 Translational long-term approach suggests loss of mucosal integrity as major driving force for progression of COPD. Rolf Ziesche, Medical University of Vienna, Austria

17:20 - 17:40 Biomarker Discovery in the Age of Big Data. Frank Schacherer, Qiagen, Germany

17:40 - 18:30 Networking & Posterviewing / Coffee & Drinks (Exhibitors)

18:30 - 19:00 Transfer to Social Event „Heuriger“ (for Speakers & Sponsors)

19:00 - 00:00 Social Event (Dinner)

Networking dinner „Bürgermeisterempfang“ at „Heurigen Fuhrgassel-Huber“ for participants on March 10, 2016 – 19:00 hrs. Registration is mandatory. (Neustift am Walde 68, 1190 Vienna, Bus line 35A, Stop „Neustift am Walde“)

PROGRAM March 10, 2016

08:30 - 09:00 Registration & Coffee

09:00 - 10:25 Session 3: Novel Sensor Technologies & POC (Chair Max Sonnleitner)

09:00 - 09:25 How to match the market requirements of microfluidics based biosensors. Max Sonnleitner, Greiner BioOne, Austria

09:25 - 09:45 The Changing Face of Point-of-Care Diagnostics. David Dolinger, FIND, Switzerland

09:45 - 10:05 Paper-based biosensors. Elvira Fortunato, Universidade Nova de Lisboa, Portugal

10:05 - 10:25 Rapid Diagnosis of Infectious Disease at Point of Care. Belinda Thompson, Atlas Genetics, United Kingdom

10:25 - 11:00 Coffee

11:00 - 12:25 Session 4: Circulating Biomarkers (Chair Eckart Meese)

11:00 - 11:25 Potentials and Limitations of blood born miRNomes in the Cancer Context. Eckart Meese, Saarland University, Germany

11:25 - 11:45 Noninvasive Biomarkers of Neurological Diseases. Balwant Rai, Kepler Space University , USA & JBR Heath Education and Research Society, India

11:45 - 12:05 The Challenge of Developing and Validating Novel In-Vitro Diagnostics Considering Increasing Regulations. Uwe Staub, Epigenomics, Germany

12:05 - 12:25 Saliva based Biomarkers for diagnosis of Oral Pre-cancer and Cancer. Jasdeep Kaur, Catholic University Leuven, Belgium

12:25 - 13:30 Lunch

13:00 - 14:00 Coffee & Poster Presentation

14:00 - 17:00 Session 5: Cutting Edge Biomarker Technologies (Chair Jörg Hoheisl)

14:00 - 14:45 Keynote Lecture 2: High-throughput, high-performance DNA-assisted protein analyses. Ulf Landegren, Uppsala University, Sweden

14:45 - 15:10 The 100,000 Genomes Project: Lessons learned from the Rare Diseases pilot. Willem Ouwehand, University of Cambridge, United Kingdom

15:10 - 15:30 Metabolic markers enable early diagnosis of heart failure and pancreatic cancer. Philipp Schatz, Metanomics Health, Germany

15:30 - 16:15 Coffee & Poster Viewing

16:15 - 16:40 Affinity Proteomics: Personalised diagnostics and therapy optimisation with fully synthetic molecules. Jörg Hoheisl, German Cancer Research Center (DKFZ), Germany

16:40 - 17:00 Quality control for the quantification of gene expression biomarkers. Mikael Kubista, TATAA, Sweden

17:00 - 17:15 Poster Prize & Closing remarks

PROGRAM March 11, 2016

Tech Gate Vienna Donau City Straße 1 1220 Vienna, Austria

www.biomarker-development.com

A special thank you to all sponsors !

AIT Austrian Institute of Technology GmbHDonau-City-Strasse 1 | 1220 Vienna, AustriaT +43 (0) 50550-0 | F +43 (0) 50550-2201office@ait.ac.at | www.ait.ac.at

www.biomarker-development.com