Program at a Glance - CCG. Osama Yasin, Zagazig University Guidance Genotoxicity Testing Prof. Azza...

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Program at a Glance

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Time

Time

RegistrationOpening CeremonySession 1 Session 2 (Cardiology)Coffee BreakSession 3 (Ophthalmology)LunchSession 4 (Pediatrics)Session 5 (Orthopedic)Session 6 (Neurosurgery)

Session 7 (Evidence Based Medicine in Academic Branches) Session 8 (Patient Physician Relationship, Medical Responsibility and Malpractice)

Conference Recommendations

09:00AM – 10:00AM10:00AM – 10:30AM10:30AM – 11:20AM11:30AM – 01:00PM 01:00PM – 01:30PM 01:30PM – 03:00PM03:00PM – 05:00PM05:00PM – 06:00PM06:15PM – 07:45PM08:00PM – 09:30PM

09:00AM – 10:30PM10:30AM – 11:30AM 11:30AM - 12:00PM

Thur

sday

Fr

iday

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ScientificProgram

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Time Thursday 24th March 2016

Prof. Maivel H. GhattasDean of Faculty of Medicine Port Said University.

Prof. Rashed El KasabyPort Said University President .

General Adel El GhadbanPort Said Governor.

Faculty of Medicine: The present & The Future Prof. Maivel H. GhattasDean of Faculty of Medicine Port Said University

The Role of Faculty of Medicine in Community Services Prof. Ehab GhoneimVice Dean for Community Services& Environmental Development Affair

Medical student Ass. Prof. Khalid SabryVice Dean for Education & Student Affairs

10:00 am – 10:10 am

10:10 am – 10:20 am

10:20 am – 10:30 am

10:30 am – 11:00 am

11:00 am – 11:10 am

11:10 am – 11:20 am

Registration

Opening Ceremony

09:00am – 10:30am

10:00am - 11:20am

Session (I) 10:30am - 11:20am

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Dr. Mahmoud El Fowi, El Amiri Hospital New guidelines in management of dyslipidemia

Prof. Ragab Abdel Salam , Zagazig university Hypertension: the gateway cardiovascular risk

Prof. Hesham Hegazy , Suez Canal University Marking a new beginning in heart failure treatment

Prof. Azza EL Eraky , Port Said University Thyroid disease and the heart, are we missing the diagnosis

Dr. Ahmed Hamam , Armed Forced College of Medicine Relation of epicardial adipose tissue volume, microalbuminuria, thyroid hormones axis to coronary artery calcium in type 2 diabetic patients

Dr. Amr Abou El Magd, Armed Forced College of Medicine Study of Retinol Binding Protein 4 Level in The Prediction of Response to Antiviral Therapy in Chronic Hepatitis C Patients

Coffee break

11:30 am – 11:45 am

11:45 am – 12:00 Noon

12:00 Noon – 12:15 pm

12:15 pm – 12:30 pm

12:30 pm – 12:45 pm

12:45 pm – 01:00 pm

01:00 pm – 01:30 pm

Session (II): Evidence Based Medicine in Cardiology

Prof. Fathi Makldy Prof. Mohamed ShoeirProf. Ahmed Al Hawary Prof. Ragab Abdel Salam

11:30am - 01:00pm

Chairpersons

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Prof. Ehab Ghoneim , Port Said University Cataract surgery in the small eye

Prof. Khalid Mansour, Cairo university Capsulorhexis related complications

Prof. Mahmoud Ismail, Al Azhar University Femto Phaco: True or false

Prof. Ahmed Mostafa , Cairo University Management of combined cataract and glaucoma.

Lunch

01:30 pm – 01:50 pm

01:50 pm – 02:20 pm

02:20 pm – 02:40 pm

02:40 pm – 03:00 pm

03:00 pm – 05:00 pm

Session (III): Evidence Based Medicine in Ophthalmology

Prof. Karem KolkailahProf. Tarek RadwanProf. Ehab Ghoneim

01:30pm - 03:00pm

Chairpersons

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Ass. Prof. Nesrin Mosaad Handoka , Port Said University Vitamin D and pediatric asthma

Prof. Azza Abdel Gawad Tantawy, Ain Shams University Transfusion therapy in pediatrics: Risks and Challenges

Prof. Suzan Samir Gad, Suez Canal University Patients safety standards

05:00 pm – 05:20 pm

05:20 pm – 05:40 pm

05:40 pm – 06:00 pm

Session (IV): Evidence Based Medicine in Pediatrics.

Prof. Mohamed El KaliobyProf. Hala Mounir AghaProf. Sonia El SharkawyAss.Prof. Nesrin Mosad Handoka

05:00 pm - 06:00pm

Chairpersons

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Prof. Mohamed Wafa , Ain Shams University Complications of surgery of degenerative scoliosis

Prof. Sherif Sokar , Suez Canal University Physiology of rotator impingrment

Prof. Hany H Lotfy , Armed Forced College of Medicine How to choose MSK imaging modality

Prof. Mohamed Wafa , Ain Shams University Spinopelvic fixation

Ass. Prof. khalid sabry , Port Said University Low back pain in children

Prof. Mohammed Ibrahim Monier , Armed Forced College of Medicine Role of Diagnostic Laparoscopy in Abdominal Trauma

06:15 pm – 06:30 pm

06:30 pm – 06:45 pm

06:45 pm – 07:00 pm

07:00 pm – 07:15 pm

07:15 pm – 07:30 pm

07:30 pm – 07:45 pm

Session (V): Evidence Based Medicine in Orthopedic

Prof. Mohamed WafaMaj. Gen. Dr Ayman Shafei Ass. Prof. Khalid Sabry

06:15 pm - 08:00pm

Chairpersons

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Ass. Prof. Ayman Galhoum, Port said University Lumbar discogenic pain

Dr. Mohamed Elsebaee, Damanhur University Current trends in the management of the brachial plexus injuries

Dr. Ali Salah Khidr , Suez Canal University Neurosurgical management of Parkinson`s disease versus best medical

Ass. Prof. Heba Youssef , Port said University Influence of drugs and substance abuse on traumatic brain injuries severity assessment among road traffic casualties therapy

Prof. Esam El Khatib , Suez Canal University Posterior Lumbar Interbody Fusion (PLIF) augmented with pedicle screw fixation in low grade lumbar spondylolithesis

Prof. Hegazy Megahed, Al Azhar University Management of neuropathy in rheumatoid arthritis

08:00 pm – 08:15 pm

08:15 pm – 08:30 pm

08:30 pm – 08:45 pm

08:45 pm – 09:00 pm

09:00 pm – 09:15 pm

09:15 pm – 09:30 pm

Session (VI): Evidence Based Medicine in Neurosurgery

Prof. Nabil HassanProf Magdy EmeraProf. Esam El Khatib

08:00 pm - 09:30pm

Chairpersons

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Time Friday 25th March 2016

Dr. Ibrahim Taher El- Serafi , Port said University Role of pharmacogenomics in personalized medicine

Prof. Refaat Sadek, Port said University Virological diagnosis of influenza viruses in a university hospital in Egypt

Prof. Osama Yasin, Zagazig University Guidance Genotoxicity Testing

Prof. Azza Zidan, Port said University Early detection of breast cancer

Ass. Prof. Mona Abdel Bary , Port said University Effect of Stem Cells Injection in Adult Male Albino Rats with Streptozotocin- Induced Diabetic Nephropathy

09:00 am – 09:15 am

09:15 am – 09:30 am

09:30 am – 09:45 am

10:00 am – 10:15 am

09:45 am – 10:00 am

Session (VII): Evidence Based Medicine in Academic Branches

Prof. Mohamed Farid El AsmarProf. Taher El-SerafiProf. Somaya HosnyProf. Maivel H. Ghattas

09:00 am - 10:30am

Chairpersons

12

Time Friday 25th March 2016

Prof. Nagah Hegazy, Zagazig University Bioethics: Benifits & harm

Ass. Prof. Heba Youssef , Port said University Medicolegal Aspect in Toxicological Emergency Management

Prof. Ahmed Elsigini , Ain Shams University Medicolegal Responsibility & Problems In Egypt

Conference Recommendations Prof. Maivel H. Ghattas

Ass. Prof. Amany Khafagy, Port said University Evaluation of physicians’ knowledge, attitude and practice regarding obtaining patients’ consent in Suez Canal University hospital - A step toward professionalism

10:30 am – 10:45 am

11:00 am – 11:15 am

11:15 am – 11:30 am

11:30 am – 12:00 Noon

10:45 am – 11:00 am

Session (VIII): Patient Physician Relationship, Medical Responsibility and Malpractice

Prof. Refaat SadekProf. Azza ZidanProf. Ahmed ElsiginiDr. Adel Tealab

10:30 am - 11:30am

Chairpersons

13

Chairpersons

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Prof. Rashed El Kasaby Port Said University President

Prof. Ehab Ghoneim - The Role of Faculty of Medicine in Community Services

- Vice Dean for Community Services& Environmental Development Affair

General Aadel El Ghadban Port Said Governor

Ass. Prof. Khalid Sabry - Medical student

- Vice Dean for Education & Student Affairs

Prof. Maivel H. Ghattas Faculty of Medicine: The present & The Future

Dean of Faculty of Medicine Port Said University

Session (I) Opening Ceremony

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Prof. Mohamed ShoeirProfessor of Internal Medicine, Faculty of

Medicine, Suez Canal University

Prof. Ragab Abdel Salam Professor of Cardiology, Faculty of Medicine,

Zagazig University

Prof. Ahmed Al Hawary Professor of Cardiology, Faculty of Medicine, Suez

Canal University

Prof. Fathi Makldy Professor of Cardiology, Faculty of Medicine,

Suez Canal University

Session (II): Evidence Based Medicine in Cardiology

16

New Guidelines in Management of Dyslipidemia

-The guidelines for lipid management have been changing since the first issue of the NCEP-ATP-I

in 1988. At that time the focus was on 1ry prevention and LDL target of 130. In 1993, LDL target

reduced to <100, HDL as CHD risk emerged and they started to Focus on 2ry prevention. In 2001 the

ATP-III emphasizes on 1ry prevention, stressed on high risk groups for 2ry prevention, there were

new risk levels (LDL<100 for all adults; HDL: 40; TG<150. Non-HDL as 2ry target for metabolic syn-

drome. CHD risk equivalent emerged and Global risk score introduced.

-Revised ATP-III in 2004 changed LDL target to <70 in high risk patients.

-The New Cholesterol Guidelines issued in 2013 by ACC/AHA replaced treat to target policy to pa-

tient centered approach aiming at ASCVD Risk Reduction. The new guidelines defined 4 statin-ben-

efit groups, High- intensity and Moderate-intensity statins.

Dr. Mahmoud Mahmoud ElfowiConsultant in internal medicine Port-Said General Hospital MRCP-UK

17

Hypertension: The Gateway to Manage Cardiovascular Risk

Measurement of BP is a simple, straightforward procedure. Elevated blood pressure (≥ 140/90 mm

Hg) is very common, affecting more than 40% of adults. Unfortunately, treatment of raised BP is

clearly inefficient to reduce the overall associated cardiovascular disease risk. People with high

blood pressure frequently have other risk factors for CVD. These include the common occurrence of

dyslipidaemia, impaired glucose tolerance, decreased GFR, proteinuria and cardiac abnormalities on

electrocardiography (ECG) and other target organ damage. Thus, the identification of hypertension

should prompt the physician to search for other risk factors and consider them as part of a compre-

hensive strategy to reduce a patient’s cardiovascular risk. This concept is important because the sim-

ple measurement of blood pressure provides what “a gateway to risk factor management” -- a simple

means of identifying people at risk for CVD prior to the onset of disease-associated symptoms and

events is an ideal concept in preventive cardiovascular medicine.

Prof. Ragab A. MahfouzProfessor of cardiology, Zagazig University

18

Marking a New Beginning in Heart Failure Treatment

HF is a complex clinical syndrome that results from any structural or functional impairment of ven-

tricular filling or ejection of blood. The absolute mortality rates for HF remain approximately 50%

within 5 years of diagnosis. Medical care for heart failure (HF) includes a number of nonpharmaco-

logic, pharmacologic, and invasive strategies to limit and reverse the manifestations of heart failure.

Prof Hesham HegazyProfessor of Cardiology, Faculty of Medicine, Suez Canal University

19

Thyroid disease and the heart: are we missing the diagnosis?

Thyroid disease is quite common. Current estimates suggest that it affects as many as 9% to 15% of

the adult female population and a smaller percentage of adult males. The cardiovascular signs and

symptoms of thyroid disease are some of the most profound and clinically relevant findings that

accompany both hyperthyroidism and hypothyroidism. Both hyperthyroidism and hypothyroidism

produce changes in cardiac contractility, myocardial oxygen consumption, cardiac output, blood

pressure, and systemic vascular resistance (SVR).

Prof. Azza El ErakyProfessor and Head of Cardiology Department, Faculty of Medicine, Port said University

20

Relation of epicardial adipose tissue volume, microalbuminuria, thyroid hormones axis to coronary artery calcium in type 2 diabetic patients

Cardiovascular disease (CVD) is the most significant cause of mortality in type 2 diabetes mellitus

(T2DM) patients. Visceral adipose tissue (VAT) may be important in sustaining the proinflammatory

background of cardiovascular disease. Epicardial adipose tissue (EAT), is a special VAT that surrounds

the major branches of the coronary artery branches and myocardium. This close anatomical relation-

ship between EAT and coronary arteries and myocardium further promotes local paracrine interac-

tions between these tissues. A calcific deposit in coronary artery are in connection with coronary

artery atheromatous plaque and is considered an indicator of atherosclerosis Microalbuminuria has

long been recognized as an important biomarker that predicts micro and macrovascular complica-

tions and mortality in patients with T2DM.Complex interplay between thyroid function and insu-

lin resistance has been implicated in diabetic dyslipidemia. Furthermore, triiodothyronine (T3) was

found to be a key signal in myocardial cells. Whether there is an association between EAT albuminu-

ria thyroid hormones to coronary atherosclerosis and coronary artery calcium is a question to be fur-

ther evaluated. Our objective is to investigate the relation between EAT volume, thyroid hormones

and microalbuminuria to coronary artery calcium in T2DM.

Dr. Ahmed Mohamed HamamAssistant Lecturer of internal medicine and endocrinology

Armed Forced College of Medicine

21

Study of Retinol Binding Protein 4 Level in The Prediction of Response to Antiviral Therapy in Chronic Hepatitis C Patients

Hepatitis C virus (HCV) infection is one of the principle causes of cirrhosis and hepatocellular car-

cinoma and has a strong impact on public health worldwide. Retinol-binding protein 4 (RBP4) is

a protein serving as a carrier of retinol in the blood, Liver is the primary source of RBP4 synthesis.

It was demonstrated that patients with chronic liver disease showed a significantly different RBP4

levels from healthy controls. These findings may reflect the impact of hepatic necro-inflammatory

activity on RBP4. The correlation between RBP4 and HCV has rarely been investigated. Meanwhile,

the impact of disease progression and severity on RBP4 in HCV deserves to be clarified. This work

had been conducted to investigate the relationship between the changes in the serum RBP4 levels

throughout the course of Pegylated interferon and ribavirin and the virological response pattern.

Also the relation between serum RBP4 and biochemical & histological characteristics of chronic hep-

atitis C patient

From the results we concluded that sustained virological response was associated with significant

reduction in RBP4 level at the end of the treatment course. However, failure to attain this reduction

in RBP4 level, and the most important is persistent elevation in RBP4 at the end of treatment was

coincident with breakthrough and relapse.

Dr Amr Abou El Magd Assistant lecture of internal medicine department


22

Prof. Karem Kolkailah Professor of Ophthalmology, Faculty of


Prof. Tarek Radwan Professor of Ophthalmology, Head of Ophthalmology

Department, Faculty of Medicine, Suez Canal University

Prof. Ehab Ghoneim Professor and Head of Ophthalmology Department,

Faculty of Medicine, Port Said UniversityVice dean for Community Service Affairs and

Environmental Development

Session (III): Evidence Based Medicine in Ophthalmology

23

Cataract surgery in the small eye

The surgical management of cataract in the small eye presents the ophthalmic surgeon with nu-

merous challenges. An understanding of the anatomic classification in addition to a thorough pre-

operative assessment will help individualize each case and enable the surgeon to better prepare for

the obstacles that might be encountered during surgery. Small eye classification, preoperative as-

sessment, biometry, associated comorbidities, intraocular lens selection, surgical issues, anesthesia,

Intraoperative considerations, postoperative issue.

Prof. Ehab Ghoneim Professor and Head of Ophthalmology Department, Faculty of Medicine,

Port Said University

24

Capsulorhexis related complications

Capsular block syndrome, Zonular dialysis, capsular phimosis, intraocular lens decentration and oth-

er related complications.

Prof. Khalid Mansour Professor of Ophthalmology, Faculty of Medicine, Cairo University

25

Femto Phaco: True or false

surgically induced astigmatism, anterior capsulorrhexis, financial aspect of femtosecond laser

technology, Is Femto cataract surgery here to stay

Prof. Mahmoud Ismail Professor of Ophthalmology, Faculty of Medicine,

Al Azhar University

26

Management of combined cataract and glaucoma.

Types of glaucoma associated with cataract, phacolytic glaucoma, phacomorphic glaucoma, surgi-

cal techniques and complications

Prof. Ahmed MostafaProfessor of Ophthalmology, Faculty of Medicine, Cairo University

27

Prof. Mohamed El Kalioby Professor of Pediatrics, Faculty of Medicine,


Ass. Prof. Nesrin Mosad Handoka Assistant Professor of Pediatrics,

Head of Pediatric departmentFaculty of Medicine, Port-Said University

Prof. Hala Mounir Agha Professor of Pediatrics, Faculty of Medicine,

Cairo University

Prof. Sonia El Sharkawy Professor and Head of Pediatrics Department,

Faculty of Medicine, Suez Canal University

Session (IV): Evidence Based Medicine in Pediatrics

28

Vitamin D and pediatric asthma

The detrimental effects of vitamin D deficiency in pediatrics have become increasingly apparent and

extend beyond skeletal health. Vitamin D may play an important role in pulmonary health by inhib-

iting inflammation, in part through maintaining regulatory T cells, and direct induction of innate

antimicrobial. Children with asthma appear to be at increased risk of vitamin D insufficiency. Evi-

dence based data suggest that low serum vitamin D in children with asthma is associated with more

symptoms, exacerbations, reduced lung function, increased medication usage and severe disease.

Ass. Prof. Nesrin Mosad HandokaAssistant Professor and Acting Head of Pediatric Department

Faculty of Medicine, Port-Said University

29

Transfusion Therapy in Pediatrics: Risks and Challenges

Transfusion of blood products is a cornerstone in managing many critically ill children and patients

with hematological diseases. Major improvements in blood product safety have not diminished the

need for caution in transfusion practice. In adults, recent progress has been made in the identifica-

tion and implementation of best transfusion practices on the basis of evidence-based clinical trials,

published clinical practice guidelines, and process improvements for blood use and clinical patient

outcomes. Pediatric transfusion practice is still highly based on adult guidelines, although children

should never be managed as young adults. In children, it is important to consider the interplay be-

tween benefits and potential adverse effects of transfusion therapy putting a challenge in decision

making.

Prof. Azza Abdel Gawad TantawyProfessor of Pediatrics

Pediatric Hematology / Oncology UnitFaculty of Medicine, Ain Shams University

30

Neonatal Safety Standards

Patient safety is defined as freedom from accidental injury. By establishing operational systems and

processes, one attempts to minimize the likelihood of errors and maximize the likelihood of prevent-

ing them.

The standard is an authoritative principle or rule that usually implies a model or pattern for guid-

ance, by comparison with which the quantity, excellence, correctness for the planning team to apply

the functional aspects of operations with sensitivity to the needs of infants, family and staff

Patients in the NICU are very small and fragile, many with immature organ systems, and superim-

posed serious illness. Such infants are likely to receive complex care from a team of experts. These

increase the potential for errors and add additional demands for a higher threshold for device safety

and efficacy.

The aim for the standards proposed by Egyptian Neonatal Safety Training Network is to embrace

nearly all health care disciplines and actors, in NICU and endorse a comprehensive multifaceted ap-

proach to prevent and manage the actual and potential risks to patient safety in NICUs.

These standards are dealing with all locations, process that newborn infants and families may

seek medical care. Starting from delivery room, outpatient clinics, private or general hospitals NICUs,

events may happen.

The standards were prepared from different sources; national and international. We are proud by

this output and have the pleasure to introduce to all colleagues in Egypt and worldwide.

Prof. Suzan Samir GadProf. of Pediatrics and Neonatology

Head of NICU, Faculty of Medicine, Suez Canal University

31

Prof. Mohamed Wafa Professor of Orthopedic surgery, Faculty of

Medicine, Ain Shams University

Maj. Gen. Dr Ayman Shafei Dean of Armed Forces College of medicine

Ass. Prof. khalid sabry Assistant Professor and Acting Head of Orthopedic

Surgery Department, Faculty of Medicine, Port-Said University

Vice dean of Education and student’s affairs

Session (V): Evidence Based Medicine in Orthopedic Surgery

32

Complications of surgery of degenerative scoliosis

In that topic, we will discuss;

-Major surgery differ than idiopathic

-Neurological, Vascular, General complications

-When to do surgery for degenerative type of scoliosis

Prof. Mohamed WafaProfessor of Orthopedic Surgery, Faculty of Medicine,

Ain Shams University

33

Physiology of rotator impingrment

Points to be discussed

-Common condition with many varieties of treatment

-Conservative, Local injections, Physiotherapy and Arthroscopic

-Understanding the underline causes essential for treatment.

Prof. Sherif SokarProfessor of Orthopedic Surgery, Faculty of Medicine,


34

How to choose MSK imaging modality

Musculoskeletal imaging deals with imaging of bone and joint abnormalities, Conventional radio-

graphs (X-rays) have been the mainstay of diagnosis, Plain radiographs are usually the starting

point, Newer modalities as “advanced imaging techniques include ultrasound ,computed tomog-

raphy (CT) and magnetic resonance imaging (MRI),. Ultrasound shows the anatomy and function of

the soft tissue surrounding bones and joints, helping us to directly observe function as the patient

moves in a real-time setting and to characterize masses. CT gives a highly detailed picture of the

anatomy of bone and the resulting changes. MRI has revolutionized the diagnosis of bone and soft

tissue conditions with its detailed depiction of anatomy and highly accurate detection of abnormal-

ities. Radiology is a double edged sword, Mistakes lead to abuse, radiation exposure, false diagnosis

or delayed diagnosis and treatment false and therefore increase morbidly and mortality. We can use

all of these techniques to guide biopsy (getting a sample of tissue or fluid) or treatment via a per-

cutaneous approach to avoid the need for hospitalization, general anesthesia and surgery in many

conditions

Prof. Hany H LoftyArmed Forces College of medicine

-Vice Dean for Research and graduate education, Armed forces College of medicine -Head of MRI Unit-Maadi Armed forces hospital

-Member of board and Assistant Secretary General; Egyptian Society of Radiology and nuclear medicine- Secretary General of the Radiology Council -Military Medical Academy

35

Spinopelvic fixation

In that topic, we will discuss;

-When we need to extend lumbar fixation to pelvis

-Different methods to do that, some old techniques

-Recent modalities for spinopelvic fixation. Conditions need extension of fixation to pelvis

-Neurogenic, myogenic, static encephalopathy

Prof. Mohamed WafaProfessor of Orthopedic Surgery, Faculty of Medicine,

Ain Shams University

36

Nano technology In Orthopedic Surgery

To be discussed

-Recent modalities of Nano:

-introduction about uses

-Clinical application and surgical uses

Ass. Prof. khalid SabryAssistant Professor and Acting Head of Orthopedic Surgery Department,

Faculty of Medicine, Port-Said UniversityVice dean of Education and student’s affairs

37

Role of Diagnostic Laparoscopy in Abdominal Trauma

The role of laparoscopy in diagnosis as well as therapeutic interventions has increased markedly in

the last few years. In trauma, it has become a viable alternative for the diagnosis of intra-abdomi-

nal injury following penetrating and blunt trauma. The number of negative and/ or nontherapeutic

laparotomies performed has decreased since the use of laparoscopy in diagnosis and management.

We concluded that Laparoscopy can be performed safely and effectively in stable patients with ab-

dominal trauma.

Dr. Mohammed Ibrahim MonierAssistant Lecturer of internal medicine and endocrinology


38

Prof. Nabil Hassan Professor of Neurosurgery, Faculty of


Prof. Magdy Emera Professor and Head of Anesthesiology and intensive

care Department Faculty of Medicine, Port-Said University

Prof. Essam El Khateeb Professor of Neurosurgery, Faculty of Medicine, Suez

Canal University

Session (VI): Evidence Based Medicine in Neurosurgery

39

Evidence-based guidelines in discogenic back pain

According to literature, short-term pain relief was defined as relief lasting at least 6 months and long-

term relief was defined as longer than 6 months, except for intradiscal therapies, mechanical disc

decompression, spinal cord stimulation and intrathecal infusion systems, wherein up to one-year

relief was considered as short-term. We concluded that the indicated evidence for diagnostic and

therapeutic interventions in discogenic back pain is variable from Level I to III.

Ass. Prof. Ayman GalhoumAssistant professor and Head of neuro-surgical department, Faculty of Medicine, Port Said University

40

Brachial plexus surgery: clinical analysis of ten cases

Brachial plexus surgery is a complex surgery and multiple surgical techniques were advanced. The

concept that patients who underwent surgery will obtain full recovery is still far from truth. In this

study, we show our results after usage some surgical techniques, aiming to describe them. Through

case series study, the team operated 10 cases, and concluded that: brachial plexus surgery renders

satisfactory results for restoring the upper limb functions. The results showing that neurolysis and

nerve transfer give better results than nerve grafting

Dr. Mohamed Elsebaee Lecturer of Neurosurgery, Faculty of Medicine, Damanhur University

41

Neurosurgical management of Parkinson`s disease versus best medical therapy

Parkinson’s Disease (PD) is the second most common neurodegenerative disorder, affecting over

1,000,000 Americans with approximately 65,000 new cases per year in the US.

We will review randomized controlled trials of different authors and centers considering the efficacy

of surgical management of Parkinson`s disease versus best medical therapy.

Dr. Ali Salah Khidr Lecturer of Neurosurgery, Faculty of Medicine, Suez Canal University

42

Influence of drugs and substance abuse on traumatic brain injuries severity assessment among road traffic casualties

Road traffic crashes (RTCs) are the leading injuries related cause of death worldwide. A clear dose

effect relationship has been demonstrated for drugs and /or substances use and traumatic brain

injury (TBI).

The objective of the study is to estimate the prevalence of drug and substances use in traumatic

brain injuries casualties. Second to assess TBI severity by selected assessment prognostic tools.

We concluded that drugs and substances abuse among road traffic casualties influence the severity

of TBI and clinical outcome.

Ass. Prof. Heba YoussefAsset. Professor of Forensic Medicine & Toxicology, Faculty of Medicine, Port-Said University

43

Posterior Lumbar Interbody Fusion (PLIF) augmented with pedicle screw fixation in low grade lumbar spondylolithesis

Seventeen patients with low grade spondylolisthesis who underwent instrumented fixation were

retrospectively analyzed from the period of 2011 to 2012. A PLIF and PSF (Group A) was performed

in 9 patients, and PLIF and percutaneous PSF (Group B) was performed in 8 patients. Data were col-

lected preoperatively and at 6 months after surgery. A comparative analysis was made between the

2 groups using visual analog pain scale (VAS) before and after surgery, and functional disability was

assessed using the Oswestry Disability Index (ODI), by which low back pain, disability was assisted

using a questionnaire and radiological (dynamic plain radiographs and CT scans) measures.

We concluded that patients with PLIF and PSF results were much better than those with PLIF and

percutaneous PSF. The postoperative back pain was much less in the percutaneous group and rela-

tively longer time for fusion. These results seem to favor PLIF with SF rather than PLIF with percuta-

neous PSF in the treatment of low grade spondylolisthesis.

Prof. Esam El Khatib professor neuro-surgery, Faculty of Medicine, Suez Canal University

44

Management of neuropathy in rheumatoid arthritis

Rheumatoid arthritis (RA) is associated with various nonarticular manifestations, including severe

neurologic abnormalities. A variety of pathogenic mechanisms are responsible:

Rheumatoid synovitis and pannus may compress or invade adjacent structures (including the spinal

cord and peripheral nerves), resulting in myelopathy, radiculopathy, and entrapment neuropathies.

Electrophysiological studies have very important roles in diagnosis of neurological involvement.

Rheumatoid vasculitis may cause ischemia, infarction, or bleeding; these may ultimately result in

transient ischemic attacks (TIA), stroke, quadriplegia, or paraparesis. With peripheral nervous system

involvement due to vasculitis, there may be multiple nerve dysfunction (mononeuritis multiplex) or

a more indolent polyneuropathy.

The introduction of newer medications since the 1990s, along with more aggressive and effective

strategies for the treatment of RA, appears to have reduced the frequency with which some of the

neurologic manifestations of RA are observed.

Extraarticular involvement in RA is a marker of disease severity and is associated with increased

overall morbidity and premature mortality

Successful management of systemic manifestations of RA is predicated upon control of the underly-

ing joint disease and often includes glucocorticoid and immunosuppressive treatments

Prof. Hegazy Megahed Professor of Neurosurgery, Faculty of Medicine, Al Azhar University

45

Prof. Mohamed Farid El Asmar

Professor of Biochemistry, Faculty of Medi-

Prof. Taher El-Serafi Professor of Biochemistry, Faculty of Medicine, Suez

Canal University

Prof. Maivel H. Ghattas Professor and Head of Biochemistry Department,

Faculty of Medicine, Port said UniversityDean of Faculty of Medicine Port said University

Prof. Somaya Hosny Professor of Histology, Faculty of Medicine, Suez

Canal University

Session (VII): Evidence Based Medicine in Academic Branches

46

Role of pharmacogenomics in personalized medicine

Personalized medicine is the customization of the healthcare. Pharmacogenomics is the corner

stone to personalize the treatment strategy in several diseases. Conditioning regimen is a major

step prior to “Hematopoietic stem cell transplantation “. Personalizing the conditioning regimen can

improve the treatment outcome and reduce its adverse effects.

Dr. Ibrahim Taher El- SerafiLecturer of Biochemistry, Faculty of Medicine, Port said University

47

Virological diagnosis of influenza viruses in a university hospital in Egypt

Influenza-like illness is a nonspecific respiratory illness characterized by fever, fatigue, cough, sore

throat, headache and other symptoms that stop within a few days.

Aim of the work: Aim of this study was to expect influenza virus as a cause of influenza like illness

depending on signs and symptoms and to compare rapid techniques and viral isolation for its di-

agnosis. Determine whether nasal or throat swabs are superior specimens to detect the seasonal

influenza virus by measuring viral load in all specimens by real time RT-PCR. Compare qPCR assays

with conventional RT-PCR to assess its potential application in routine surveillance and diagnosis.

The mean, median, standard deviation and range of viral load by nasal swabs are higher than those

of throat swabs denoting that nasal swabs are more useful diagnostic tools in diagnosis of influenza

than throat swabs.

Prof. Refaat Sadek Professor and Head of Medical Microbiology and Immunology Department, Faculty of Medicine,

Port said Universitymember of Egyptian scientific committee for graduation of Professor and assistant Professor

48

Guidance Genotoxicity Testing

Materials in the nanoscale are used in many commercial products and industrial practices in the

new millennium. This article, would like to briefly discuss the methodologies currently available for

genotoxic studies and present a survey of the in vitro and in vivo genotoxicological studies conduct-

ed in recent years. Genotoxicity tests include: 1- Single Cell Gel Electrophoresis assay (comet assay)

that is an uncomplicated and sensitive technique for the detection of DNA damage at the level of

the individual eukaryotic cell. 2- The micronucleus test (MN): for assessing chromosome damage

because they enable both chromosome loss and chromosome breakage to be measured reliably.

3- Sister-chromatid exchange (SCE) that is the process whereby, during DNA replication, two sister

chromatids break and rejoin with one another, physically exchanging regions of the parental strands

in the duplicated chromosomes. 4- The Ames test that was developed in the 1970‟s by Bruce Ames.

Because the assay does not use a live animal model, it is inexpensive, easy, and fast. The guidance

only applies to small-molecule, non-biological pharmaceutical products intended to be used in hu-

man subjects. Genotoxicity tests are used to determine whether a pharmaceutical compound in-

duces genetic damage to a subject, which can cause a wide range of problems including cancer and

heritable birth defects. The guidance notes a “battery approach” to genotoxicity testing is preferable

given the broad spectrum of potential events and the limits of single-test analysis, and describes the

requirements of conducting genotoxicity battery tests by OECD 2014.

Prof, Osama Yasein IbrahimProfessor of Histology and Cell Biology, Faculty of Medicine, Zagazig University

49

Effect of Stem Cells Injection in Adult Male Albino Rats with Streptozotocin-In-duced Diabetic Nephropathy

Diabetic Nephropathy is a leading cause of end-stage renal disease and the most frequent cause

of mortality in patients with diabetes. Therefore, it is extremely important to identify novel inter-

ventions to halt the progression of diabetic nephropathy. This study investigated the effect of hu-

man umbilical cord blood (HUCB) derived (CD34+) stem cells therapy on renal morphologic and

functional changes and alterations of kidney enzyme levels in streptozotocin (STZ)-induced diabetic

nephropathy in rats.

This study concluded that HUCB CD34+ cells transplantation in diabetic rats is able to improve blood

glucose level, partially ameliorate the renal damage in diabetic rats and consequently improve renal

function, renal histology and renal enzyme levels alteration.

Ass. Prof. Mona Abdel BaryAssistant professor and Acting Head of Physiology Department, Faculty of Medicine Port said University

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Effect of Stem Cells Injection in Adult Male Albino Rats with Streptozotocin-In-duced Diabetic Nephropathy

Breast cancer is the world’s most common cancer among women, and the most likely cause of wom-

en death from cancer worldwide

Points to be discussed:

-Different morphological histopathological patterns of cancer breast

-Different ways for classification of cancer breast: either on hormonal basis (ER, PR and HER2) or,

based on molecular features.

Prof. Azza zidanProfessor and Head of Pathology Department, Faculty of Medicine, Port said University

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Prof. Refaat Sadek Professor and Head of Microbiology

Department, Faculty of Medicine, Port said University

Prof. Azza zidan Professor and Head of Pathology Department, Faculty

of Medicine, Port said University

Dr. Adel Tealab Director of the Directorate of Health in Port Said

Prof. Ahmed Elsigini Professor of Forensic Medicine and Toxicology

Faculty of Medicine Ain Shams University Former Director Manager for Forensic Medicine

Consultation Unit ASU

Session (VIII): Evidence Based Medicine in Academic Branches

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Bioethics: Benefits & harms

Medical ethics are more concerned with the ethics of the health care professionals and their relation-

ship with the patient. They are concerned with many topics like:

-Abortion

-Organ transplant, artificial ventilator, and brain death

-Euthanasia

-In vitro fertilization (IVF)

-Stem cell research

-Genetic engineering

-Doctor patient relationship

Prof. Nagah Ibrahim Hegazy Professor of Forensic Medicine & Toxicology, Faculty of Medicine, Zagazig University

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Evaluation of physicians’ knowledge, attitude and practice regarding obtaining patients’ consent in Suez Canal University hospital - A step toward professionalism

Informed consent means that the treating health care provider discloses appropriate information to

a competent patient so that the patient may make a voluntary choice to accept or refuse treatment.

It legitimizes medical interferences, keeps patient’s rights and freedoms, acting without it is usually

illegal.

This study concluded that postgraduate training concerning ethical issues of obtaining and

documenting patients’ informed consent for medical procedures should be offered to graduates

before they start their clinical training.

Ass. Prof. Amany AhmedAssistant Professor of Forensic Medicine & Toxicology and Acting head of Forensic Medicine & Clinical Toxicology

department, Faculty of Medicine, Port-Said University

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Medicolegal Aspect in Toxicological Emergency Management

One of the most important duty in treating acutely intoxicated patients is the medico-legal aspect

of the case. The doctor in charge at a Government or Public hospital is supposed first to manage the

cases effectively and according to evidence based protocol of management, document all cases and

report to the Police all cases of poisoning which may be suicidal, homicidal or accidental admitted

to his institution because it is also a part of his duties to protect the society. In case of death, a death

certificate should not be issued but the fact of death must be communicated to the nearest Police

station for necessary investigation.

Ass. Prof. Heba YoussefAssistant professor of Forensic Medicine & Toxicology, Faculty of Medicine, Port-Said University

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Medicolegal Responsibility & Problems in Egypt

Discussion about: physician patient relationship and medical malpractice

Prof. Ahmed Ibrahim ElsiganiProfessor of Forensic Medicine & Toxicology and former director of Forensic Medicine Consultation Unit, Faculty of

Medicine, Ain Shams University

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Sponsors

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Sponsors

El-Shorbagy BMG

HiMed Ortho Care

Global Pharma

58

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Program at a Glance - CCG. Osama Yasin, Zagazig University Guidance Genotoxicity Testing Prof. Azza...

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