UNDER THE HIGH PATRONAGE OFTHE PRESIDENT OF THE REPUBUC OF ITALY

PROCEEDINGS OF THE

VI MEDITERRANEAN CONFERENCE ONMEDICAL AND BIOLOGICAL ENGINEERING

JULY 5- 10, 1992

CAPRI - ITALY

VOLUME I

Editors:

M. Bracale and F. Denoth

AREA Dl RICERCA - CNR - PISA

o UB/TIB Hannover117 671 045l Mill mil ll« 11 mi mil inn inn IIIII urn uin nni ii

XIII

TABLE OF CONTENTS

VOLUME I

PAPERS

SESSION OPEN: OPENING

Biomedical Engineering in Europe: Where should the emphasis be put?BenekenJ.E. 3

SESSION GIUV1: GIUV I

Investigation of Peripheral Circulation at Major Swedish HospitalsVolkmann ft, Fagrell B., Holm J 7

Methodological Aspects on Venous PlethysmographyVolkmann ft, Bergerheim T, Holm J. 9

Organisation of the Vascular LaboratoryTaft A 13

The Vascular Diagnostic Laboratory in the United StatesNeumyer MM 15

The Vascular Laboratory in ItalyBorgatti E., De Fabritiis A., Emiliani L.Filippini M., Martignani A 1 9

Ultrasound for Vascular Application in NeurologySliwka U., Rautonberg W., Hennerici M. 23

Venous Testing: Medical, Social and Economic ImpactNicolaides A.N. 27

SESSION GIUV2: GIUV II

Color Doppler in Evaluation of Renal Artery DiseaseAmato A, De Fabritiis A, Borgatti E. 31

Experimental Comparison of In Vitro Carotid Ultrasound Images with ActualDigitized Anatomical SectionsRighi D., Capinori L, Castellini G., Gori F. 35

New Findings in Non Invasive Diagnostic Techniques of Deep Venous ThrombosisAntignani P.L 39

The Early Alteration of Shear Stress on the Arterial Wall in Patients with VascularRisk Markers and without Vascular Disease: Evaluation by Ecoduplex ScannerSignorelli S.S. 43

Ultrasound Detection of Venous ThrombiAnnoni F., De Stefano A. 4g

Ultrasound Investigations in the Postoperative Control of Arterial Graft of theLower LimbsGossetti B., Martinelli O., Fomasin F.R., trace L, Benedetti-Valentini F. 53

XIV

SESSION NEU_SP1: ELECTROMYOGRAPHY AND BIOELECTRICAL PHENOMENA

Acousticographic and Electromyographic Patterns of Verbal Motor ControlPinelli P., Ceriani F., Miscio G., Pisano F. .' 5 7

Computerized Analysis of Speech and Electromyographic Patterns of Speech MotorControlGrandori F., Pinelli P., Ceriani F., Miscio G., Pisano F., Insalaco S., Ravazzani P. 61

Gaze Control in ManSchmid ft, Zambarbieri D 65

Modeling of Surface EMG during Isokinetic TestCesarelli At, Castaldo ft, Pepino A, Spiezia A, Bracale M., Marasco E., Fazioli G. 69

Separation of Travelling from Non-Travelling Components in Surface MyoelectricSignalsRubio J., Merletti ft., Fan Y. 73

SESSION PHAR_M: PHARMO KINETIC MODELLING

A Multi-Region Distributed Parameter Model for Measuring Glucose Transport inthe Human Skeletal Muscle from Indicato Dilution DataVhini P., Saccomani M.P., Bonadonna ft, Cobelli C. 7 7

Evaluation of Calcium Kinetics as a Tool for Bone Turnover in Comparison toBiochemical ParametersWerner £., Roth P., Spielberger I., Hanson CH. 8 1

Modelling of Lidocaine-MEGX Kinetics to Assess Impairment of Liver FunctionHovorka ft, Fried M., Jones E.A., Di Bisceglie AM, Carson E.R. 8 5

Pharmacometric Modeling by using Bayesian NetworksBellazzi ft, Berzuini C. 8 9

Physiological and Pharmacokinetic Modelling of Trace Element MetabolismHanson CH., Roth P., Werner E., Cantone M.C., de Bartolo D., Gambarini G., Molho A/.,Pirola L 93

SESSION BI0MAT1: BIOMATERIAL AND PROSTHESES

Blends of PVA with Collagen, Gag, Fibronectin as New Bioartificial Materials. I. TheSystem PVA and CollagenGiusti P., Lazzeri L., Barbani N., Narducci P., Palla M., Lelli L 97

Development of an Implantable Neural Connector for Limb Prostheses: In VitroInvestigationsCocco M., Toro M., Migliorini P., Bongioanni P., Sabatini AM., Dario P., Sacchetti ft,Schmidt H. 101

Microbial Colonization of Catheters Explanted from Nephropathic ChildrenGelosia A., Baldassarri L, Mignozzi M., Fiscarelli £., Rizzoni G., Donelli G 1 05

Shape-Memory Alloy Intravascular Endoprosthetic Stents: Design and In Vitro TestsMontesi M.C., Valleggi ft., Trivella M.G., Bergamasco M.. Salsedo F., Dark) P. 1 09

The Effect of Temperature on the Dimensional Variation of Composite ResinsFano V., Ortalli I. 1 1 3

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Tribological Behaviour of UHMWPE Acetabular Cups against Differently TreatedTi-6AI-4V Prosthetic HeadsCigada A, Brunella M.F., Pezzi D 1 1 7

SESSION BIOSP1: BIOMEDICAL SIGNAL PROCESSING I

A New Class of Digital Filters with Applications in Biomedical Signal ProcessingVarri A, Neejarvi J., Neuvo Y. 121

A Tool to Control Biosignal Processing with an Application to Analyse EsophagealFunctionFaust U., LiuJ. 125

Adaptive Identification of Visual Evoked Potentials, Application to MultiparametricStimulationBrikou A.K., Moustakides G.V., Bezerianos A, Papathanasopoubs P. 1 29

Analogical and Digital Filtered Acquisition of Fetal Electrocardiogram byTransabdominal RecordingBortone A, Cicinelli E., Incampo G., Carbonara I., Schonauer S., Rizzon P. 1 33

Improvement of the Diagnostic Sensitivity of the BAEP Amplitudes afterNormalization for Skull Thickness and Head SizeNikHoridis G., Koutsojannis C, Karamitsos D 137

Spectral Analysis of Dystonic Movements with Application of Linear ModelsScholz U., WisselJ., Mainardi L, Poewe W. 141

The European ST-T Database: A Standard for Evaluating Systems for the Analysis ofST-T Changes in Long-Term ECGTaddei A, Distante G., Emdin M., Pisani P., Moody G., Zeelenberg C, Marches'! C. 1 45

SESSION MED_DM1: MEDICAL DATA MANAGEMENT I

Diagnostic Procedures based on a New Medical Imaging ConceptAnastassopoulos G., Kotsopoulos S., Lymberopoulos D., Goumas P. 1 49

Networked Portable Digital Radio for the Hospital EnvironmentMitchell CM., Matthews J.G.W., Evans N.E., Black N.D. 1 53

Object-Oriented Generator of Documentary Banks Application to Head TraumaFroment J.C.. Azencot J., Unterreiner ft, NKSbesso ft 157

Progressive Image Transmission Methods for Biomedical Data Bases AccessArgenti F., Cappellini V., Venetsanopouhs AM 1 61

Unified Medical Data Management on Medical WorkstationsAnastassopoulos G., Lymberopoulos D., Kotsopoulos S., Kokkinakis G. 1 65

SESSION IM_PR01 : MEDICAL IMAGING I

A Computer Assisted Method for Image Feature Extraction and Analysis based on B-spline AlgorithmMarchetti A, Guo Y.H., Azzarelli L., Chimenti M. 169

Automatic Detection of Left Ventricular Endocardium on UltrafastTomodensitometric ImagesBastide N., Herment A, Dumee P., Mousseaux £ , Peronneau P. -j 73

XVI

Correcting Local Distortion for Automatic Comparison of Electrophoresis ImagesWang O.,Neuvo Y. 177

Non-Invasive Hemodynamic Cerebrovascular Parameter Evaluation from InputImpedance Ultrasound MeasurementsEvangelisti A, Powalowski T., Trawinski Z. 181

Some Preliminary Notes about the Use of 'CAD1 Strctures for the Pre-operativePlanning of Intertrocantheric OsteotomiesPepino A, Mosca A, Cesarelli At, Di Salle F., Bracale M. 185

Spatial Characterization of Non Regular Anatomical StructuresCaramella D., Braccini G., Salvetti O., Guelfi ft., Masoni M. 189

SESSION NEU_SP2: EEG AND EVOKED POTENTIALS

A Model for the Magnetic Stimulation of Human Cortex and Peripheral NervesRavazzani P., Grandori F., Piavani A, Vardanega M.G 1 93

A Study of Slow Changes in the EEG Activity during SleepBarcaro U., Bizzari M., Bonanni £., Denoth F, Mum' L, Navona C. 197

A Study of Surface Wave Propagation in the CNVBarcaro U., Denoth F., Navona C, Versari A, Zappoli ft 201

Analysis of Human Brain Evoked Potential on a Single Trial Topographic BasisLiberati D., Cerutti S., Comi G., Locatelli T. 205

Automatic Epileptic Spike Detection by Median Filtering and Simple ArithmeticSharp Transient Detector: A Clinical EvaluationKrajca V. Pettranek S, Patakova I., Ondruska V. 209

Brain Synergies in Simultaneous Bisensory Stimulation: Recognizing and ModelingCortico-Cortical InteractionsLiberati D., Brandazza P., Cerutti S., Cursi M. 21 3

Comparison between two Techniques for Recording Otoacoustic EmissionRavazzani P., Grandori F. 21 7

Electric Induced Field Stimulation Technique using Toroidal Coils. An Application toEvoked PotentialsFerrero J.M., Robles M., Guijarro £., SAiz J., Ferrero J.M.Jr., Mocholl A 221

SESSION PHY_MOD1: PHYSIOLOGICAL MODELLING I

A Comparative Evaluation of Models for the Aortic Input ImpedanceAvanzolini G., Cappello A, Gnudi G 227

A Computer Study on Feedback Control of Glucose Concentration throughSubcutaneous SensorsFabietti P.G., Filippucci F., Crucian! P., Sarti E. 231

A Mathematical Model to Study the Relationship between the Haemodynamics of theMain Cerebral AreasFabbri G., Ursino M. 235

Hormone Secretion Rate Estimation via Spectral Analysis and Deconvolution of theBlood ConcentrationDe Nicolao G., Liberati D. 239

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Improvement of Numerical Interpretation of Healthy Newborn Human BloodViscometric MeasurementsMartino ft, Trevisan F., Cesaro M., Cattozzo V., Cason C, Bettini V., Masiero G. 2 4 3

Numerical Simulation of Stress inside a Skin-like Tactile SensorColli Franzone P., Germagnoli F., Guerri L, Magenes G 2 4 7

Theoretical Implications of Capacity Vessel ControlUrsino At, Belardinelli £., Di Gianmarco P., Antonucci M. 2 5 1

SESSION BI0MCH1: GAIT ANALYSIS

A Large Platform for the Detection of Foot-To-Floor Pressure DistributionMacellari V., Giacomozzi C, Torre M. 2 5 5

Accuracy of the Determination of the Instantaneous Helical Axis for In-VivoApplicationsFioretti S., Leo T, Maurizi M. 2 5 9

An Algorithm for Automatic Movement Detection by means of Professional TVCameraCukush Z , Cecic At, Zanchi V, 2 6 3

Evaluation of Asymmetry of Hemiplegic Gait using Electromyographic PhasicActivityChen J.J., Liou J.J., Hwang I.S., Lin S.I., Huseih T.C. 2 6 7

Gait Evaluation Method in Patients with Implanted Hip ProsthesesStanic U., Herman S., Merhar J., Demsar H, Kljajic N., Malezh At, Vrtacnik P.,Acimovic-Janezic ft, Kljajic M. 2 71

Interpretation of Pre-operative and Post-operative Results of Gait in Patients withTotal Hip ReplacementHerman S., Stanic U., Merhar J., Demsar H, Kljajic N., Malezh At. Vrtacnik P.,Acimovic-Janezic ft, Kljajic M. 2 75

Kinematics of the Lower Limb Joints during GaitCheze L, Gignoux P., Dimnet J., Carrot J.P. 2 7 9

Optimum Proportions of Human Arm Mechanism with respect to its WorkspaceLenarcic J., Umek A 2 8 3

SESSION CEL_EN: CELLULAR ENGINEERING

Analysis of Micromechanical Parameters of Erythrocytes - A Cell Bioassay forIndirect Examination of Drug Effects on Red Blood CellsArtmann G 2 8 7

Aspiration Experiments of Passive Leucocytes Into MicropipettesBucherer C, Geiger S., Lacombe C, Lelievre J.C. 2 9 3

Biomimicry for Chemical and Physical SensingRotfeP. 2 9 7

Cellular Engineering and Burn Treatments from a Dermal Substrate to aReconstructed SkinDamour O., Echinard E. 3 01

XVIII

Cellular Engineering: The Role of the Engineer in the Biological EvolutionNeremRM. .307

Characteristic Locations of Residues in Globular ProteinsRuggiero C , Sacile R 309

Coculture of Endothelial Cells with Smooth Muscle Cells in a Collagen MatrixZiegler T., Nerem RM. 51 3

Image Analysis of Cell Movement in Predicting Biological BehaviourKomotowski D., Kunz M. 51 7

Micromechanical Behaviour of Neutrophils Via Micropore Filtration ApproachNikita K.S., Uzunoglu N.K., Koutsouris D. 321

Modulation of Cell Cycle by Low Level Direct Current in CancerVodovnik L, Miklavcic D., Sersa G .325

Modulation of Single Channel State TransitionsSalvaggio A 529

Molecule Diffusion Simulated in Computer Modelled Brain TissuesLipinskiH.G 533

Organised Protein FilmsAhluwalia A, De Rossi D. 3 3 7

Red Blood Cell Properties Studied by Ultrasonic InterferometryRazavian At, Gamghi N., Coulibali H., Guillet ft., Beuzard Y, Boynard M. 341

The Bio/Electronic Interface: State of the Art and ProspectsGrattarola At, Martinoia S., Cambiaso A 345

SESSION MEDJN: MEDICAL INSTRUMENTATION

A New CCD Microscope and its Application to the Analysis of the Effects ofNitroglycerin on Porcine Coronary VenulesYada T., Kimura A, Yamamoto T., Hiramatsu O., Goto At, Ogasawara Y., Tsujioka K,Kajiya F. 549

A New Microcomputer Controlled Solid-State Ocular FluorophotometerHamidO, Jones DP., 553

A Proximity Communication Link for Physiological Data AcquisitionMcCreesh Z, Evans N.E. 3 5 7

Evaluation of Chest Volumes during RespirationFerrigno G., Camevali P., Molteni F., Pedotti A 361

FRP II: Wide Range High Resolution Low Cost Blood Velocity ProfilerBardelli At, Carretta ft., Di Paolo G., Dotti D., Dotti F., Lombard! ft 565

Portable ElectroventilationDempsey G.J., Cochrane D., Anderson J., Allen D., Adgey J. 369

Study of the Electrode-Skin Interface Behaviour in Switching TransientsFerrero JM.Jr., Saiz J.F., Ferrero J.M., Robles At, Guijarro £., Arnau A 373

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SESSION CARDIO1: CARDIOVASCULAR MODELLING AND MEASUREMENTS

Computer Simulation of Flow Phenomena in Distensible Arterial Bifurcation ModelsPerktold K, Peter R.O., Gurtl R : 5 7 7

Local Point Spread Functions (PSF) in Positron Emission Tomographic (PET)SlicesLabb6 C, Rouseet O., Lavenne F., Landais P., Cinotti L 5 8 3

Model of the Carotid Arterial Impedance in the PigBurattini ft, Montanari L, Mulligan L.J., Gross D.R. 5 8 7

Regional Myocardial Function Curve of the VentricleKondoh Y.Sugawara At, Nukano K, Uchida K. 5 9 1

The Measurement of Electrical Myocardial Impedance as a Method for RejectionDiagnosis after Heart TransplantationMueller J., Wamecke H., Cohnert T., Nelson B., Hetzer ft 395

SESSION EL_STIM1: ELECTRICAL STIMULATION

A Neurophysiological Model of the Long-Term Antispastic Effect of TherapeuticElectrical Stimulation (TES) in Hemiplegic PatientsAlfieri V. .401

A Voice Activated FES System for the Restoration of Hand Movements in PlegicSubjectsD'Alessb T, Bonato P., Capozza At, Falaschi A, Inghilleri At, Modugno A .405

Effects of the Electric Current on Partial Oxygen Tension in Wound SurroundingLikar B., Poredos P., Preseren At, Klesnik At, Vodovnik L 409

Electric and Magnetic Stimulation of Human Peripheral NervesNilsson J., Panizza At, Roth B.J., Basser P.J., Cohen L.G., Caruso G., Hallett M. 41 3

Self-Controlled FES System for ParaplegicsIsakov £., Mizrahi J. .41 7

Sensory Feedback for Enhancing FES in Spinal Cord Injured PatientsKraljA, Los At, Munih At, Bajd T, Turk ft 421

SESSION ART_ORG: CARDIOVASCULAR IMPLANTABLE DEVICES

Arterial Graft Shape and Shear-Stress at the WallCavakanti S., Belardinelli E. .425

Computer Flow Simulation on the Performance of Parallel Corotating Disks as aHeart Assist DevicePinotti At, Rosa E..S .429

Distributed Effects of a Stenosis along an ArteryCavakanti S., Belardinelli E. .433

Prosthetic Heart Valve Evaluation In Vitro: Technical and Methodological Aspects ofPulsatile TestingBarbaro V., Daniele C, Grighni At, Palombo A 437

Research and Development on Implantable Total Artificial Heart (TAH) in JapanKazuhuko A, Iwao F., Kou I., Kunihiko At, Tsuneo C, Yusuke A .441

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SESSION HRV: HEART RATE VARIABILITY

Approximate Dimension and Entropy to Measure the Complexity of Heart RateVariability in Healthy SubjectsBalocchi ft., Michelassi C, Carpeggiani C 445

Estimation of the Power Spectrum for the Analysis of Variability with Time-Frequency DistributionsPola S., Emdin At, Macerata A, Varanini At, Conforti F., Carpeggiani C, Marches'! C. 449

Modelling the Baroreflex: A Matter of BalanceTenVoorde B.J., Rompelman O., Faes TH.J.C, .453

Parametric Spectral Analysis and Chaotic Modelling of Cardiovascular VariabilitySignalsCerutti S., Signorini M.G., Bianchi A, Lissandrello F., Solari S., Montefusco A, Furlan ft,Malliani A -457

Quantitative Correlation between EEG and HRV Signal during Different Sleep StagesBianchi AM., Schoulz U., Cerutti S., Kubicki S., Padovani P. Panizza F. 461

Time-Variant Spectral Estimation Algorithms for the Study of Transient IschemicEpisodesMainardi L., Bianchi A., Stagni A, Signorini M.G., Bertinelli At, Cerutti S 465

SESSION SURG: TECHNOLOGY FOR SURGERY

A New Bleeding-Controlled Bladder Irrigation System for Post-operativeTreatment after Endoscopic SurgeryKreutzkj T., Sommerkamp H., Bruckner B., Hakenberg O., Popken G., Koppermann U. 469

A New Technique to Control Biliary Tract Functions after SphincterotomyBaxa P., Cherubim' At, Walcher G. 473

Analysis of the Accuracy of a Robotic Procedure for Knee ArthroplastyMartelli S., Fadda At, Dario P., Marcacci At, Visani A .477

Co Laser Angioplasty SystemKikuchi At, Arai T, Mizuno K, Takeuchi K, Utsumi A, Akai Y. 481

Revolutional Challenge for Future Medicine by Laser ApplicationKazuhikoA .485

Surgical Planning in Virtual Reality, by means of an Instrumented ToolholderGiorgi C, Beltrame F., Luzzara At, Marcenaro P. 489

The Use of CAD Techniques for the Preoperative Planning of IntertrocanthericOsteotomiesPepino A, Mosca A, Cesarelli At, Di Salle F, Bracale M. .493

SESSION HRVP: CARDIOVASCULAR VARIABILITY SIGNAL

A Study of Blood Pressure Control via a New Method for the Analysis of the BloodPressure SignalAlmog Y., Akselrod S .497

XXI

Are Main Spectral Features of the Arterial Pressure Variability Signal Modifiedwhen Measurements are taken from a Non-Invasive Finger Blood PressureMonitor?Pinna G., Maestri ft, Di Cesare A, La Rovere M.T., Mortara A * 5 0 1

Role of Baroreceptors in Controlling Long Term Modulations of Blood Pressure andPulse IntervalDi Rienzo At, Castiglioni P., Parati G., Omboni S., Ramirez A.J., Pedotti A 505

Time-Qualified Prediction Limits for Circadian Blood Pressure Variability inClinical HealthFernandez J.R., Hermida R.C., Ayala D.E., Cid V., Mojon A 509

SESSION IM_PRO2: MEDICAL IMAGING II

3D Reconstruction of Vascular Structures from two Angiograms by SimulatedAnnealingPellot C, Herment A, Sigelle At, Horain P., Peronneau P. 513

Integrating Statistical and Spatial Information in Medical Image SegmentationCarreira M.J., Cabello D., Mosquera A, Penedo M.G 5 1 7

Measurement of the Flow Field in a Normal Left Ventricle using Magnetic ResonancePhase Velocity EncodingWalker P.G., Scheidegger M.B., Cranney G.B., Pohost G.M., Yoganathan A.P. 521

New Realization of the Image ReconstructionBogorodzki P., Piatkowski A 5 2 5

Quantitation of Regional Myocardial Blood Flow by Constrast EchocardiographyMor-Avi V., David D., Bitton Y., Keselbrener L, Akselrod S 5 2 9

SESSION REHAB1: REHABILITATION ENGINEERING

Communication and Environment Control System for QuadraplegicsOberle A, Bach G., Gauthier G.M., Vercher J.L. Dollfus P. 5 3 3

Left Ventricle Boundary Detection with Kohonen MapsManhaeghe C, Lemahieu I., Vogelaers D 5 3 7

Model of an Experiment Design in Rehabilitation and Physical Activity StudiesBogataj U., Kljajic At, Gros N., Acimovk-Janezic ft 5 4 1

Optimization of the Robotized System 'MASTER' after the Clinical EvaluationDetrkhe JM., Lesigne B. 5 4 5

Research into Optimising Hand and Body Function for Tasks in Everyday Living -The Development of a Range of 'Easy Use' Saucepan HandlesBrown F.R., Torrens G.E., Wright D.K. 549

Restoration of Upper Limb Function to Tetraplegics using Neural Networks and aVoice Processing SystemCliquet AJr., Mendeleck A, Ouesnel D.R.F., Sovi F.X., Feli[e PJr.. Oberg T.D., LemosG.J.P., Guimaraes E.A., Ouevedo A.A.F. 5 5 3

SESSION CLDEV1: BIOMEDICAL AND CLINICAL ENGINEERING

A European course on Biomedical Engineering and on Medical PhysicsProimos B.S 5 5 7

XXII

Activities of the Centre for Information and Evaluation of Biomedical Equipment ofTriesteBravar D., Fonda S., Giribona P 561

An Experimental Set-Up for Measuring the Output of Extra-Corporeal Shock WaveLithotriptersBuizza A., Dell'Aquila T., Giribona P., Spagno C. 565

Decision Support System for the Management of Biomedical Equipment at a RegionalLevelLamberti C, Marsili A, Carota L, Roversi £., Gnudi G., Avanzolini G 569

Electrical Safety in Operating Room Monitors. Measures and ControlsSanchez J.C., Garcia T., Sanz F., Sanz J.L 573

The Clinical Engineering Department as a Private Enterprise within the HealthCare SystemOberg P., Bostrom U., Strom I. 577

SESSION DIA_SYS1: DIAGNOSTIC SYSTEMS

A Prototype System for the Continuous Monitoring of Meconium in Amniotic Fluidduring LabourGenevier E.S.G., Danielian P.J., Steer P.J. 581

Electric Current Distribution and Temperature Evaluation under NoninvasiveCurrent ElectrodesLambert H.L, De Mey G.A, De Bisschop F.R., Vanderstraeten G.G., De Cuyper H.J. 585

Feasibility Study of a Method for Monitoring Anaesthetic DepthRosenfalck A, Nerregaard Christensen K, Eckhart Thomson C, Gade J. 589

Quantitative Estimation of Visual Fatigue through Analysis of Pupillary LightResponseHoshino K, Saito M. 593

Respiratory Impedance during Conventional Mechanical VentilationBarbini P., Cevenini G., Massai Af.ft, Ursino At 597

Volume Flow Rate Measurement in Fleisch Pneumotachograph Considering HeatExchangeBarbosa R.B., Figueiredo A.M.D., Giannella-Neto A 601

SESSION TECH_A1: TECHNOLOGICAL ASSESMENT 1

Measurement of the Output of Commercial Extra-Corporeal Shock WaveLithotripters for Kidney StonesBuizza A, DeWAquila T, GirhonaP., Spagno C. 605

Measuring Health Benefits in Technology AssessmentHutton J. 609

Program for the Assessment of High-Technology Health Care Devices in JapanKikuchi M. .615

Prosthetic Heart Evaluation In Vitro: The FDA Interlaboratory Comparison TestingProtocol Applied on Two Different Pulse DuplicatorsBarbaro V., Daniele C, Grigtoni At, Pabmbo A 619

XXIII

Quality Control of Mammographic Units in GreecePanayiotakis G., Giakoumakis £., Flbni-Vyza A, Xenofos S., Proimos B. 623

Study of Phantoms for the Validation of a Fluorescence Detection System Using aKrypton Laser: Application to Cancer Diagnosis in Phodynamic TherapyDiller M.L, Granjon Y., Guillemin F., Meunier-Reynes A, Yvroud E. 627

Subjective Quality of Care and Safety and the Use of Medical DevicesPersson J., Ekberg K. .631

Technology Assessment and the Medical Equipment IndustryHutton J. .635

Why Technology Assessment?Porsson J. 637

SESSION BI0MAT2: ELLULAR AND TISSUE BIOMECHANICS

Cyclic Stress Fatigue Changes in ArteriesMcCord B.. Aoki T., Ku, D. .639

In-Vitro Electric Properties of Femoral BoneDo Mercato G., Garcia sAnchez F.J. 643

Micromechanical Behavior of Neutrophils Via Micropore Filtration ApproachNikita K.S., Uzunoglu N.K.. Koutsouris D. 647

The Influence of Hydration and Preconditioning on the Failure of Stratum CorneumNikolopoulos C. Barbenel J.C. .653

SESSION US_VASC: ULTRASOUNDS IN CARDIOVASCULAR SYSTEM I

Analysis of Blood Velocity into Myocardium during Coronary Artery Stenosis by 20MHz 80 Channel Pulsed Doppler Velocimeter in DogsKajiya F., Kimura A., Yada T., Hiramatsu O., Tokuda C. Ogasawara Y., Goto At, TsujbkaK. .657

Cardiac Output Measurement with a New Perivascular Multi-element DopplerTransducerKim W.Y., Pedersen EM.. Semod L, Hasenkam J.M., Nygaard H., Paulson P.K. 661

New Developments in Cardiac Ultrasound TechnologyBom N., Do Kroon M.GM. 665

Possible Improvement of Color Flow Images by Adaptive Estimation of the MeanFrequency of the Doppler SignalHerment A, Peronneau P., Pellot C. 669

Quantitative Mapping of Turbulent Stresses Downstream of Mechanical Aortic ValvePhrosthesis in Humans using Perivascular Doppler UltrasoundNygaard H.. Paulson P.K, Hasenkam J.M., Pedersen EM., Rovsing P.E. 673

Spatial and Temporal Development of Velocity Profiles in the Porcine MainPulmonary ArteryHasenkam J.M., Somod L, Pedersen EM., Kim W.Y., Rovsing P.E. 677

Transverse Doppler: A Novel Ultrasound Technique for Accurate Flow VelocityMeasurementsTortoli P., GuidiG., Valgimigli F., Atzeni C, Newhouse V.L 681

XXIV

SESSION BIOMCH2: BIOMECHANICS

Analysis of the Influence of Femur Resection in Hip ArthroplastyBignardi C, Calderale P.M. 685

Biomimetic Approaches to the Design of Materials for Artificial Haptics andManipulationDe Rossi D., Domenici C, Chiarelli, P., CanepaG 6 8 9

Experimental and Numerical Methodologies for Dental Implants EvaluationCalderale PM., Rossetto M. .693

Muscle Bending Profiles in Different Body PosturesMunih At, Kralj A 697

The Biomechanics of Pin-Bone Interface of Three External Fixation Pins on IliacCrestLiuJ., Chang G.L. Chang W.S., Lai K.A., Chou Y.L 701

The Use of Digitised Videofluoroscopic Images in the Analysis of Spinal MechanicsIn-VivoKondracki At, Breen A, Allen ft 703

Three-Dimensional Orifice Geometry Correction is Required for CalculatingRegurgitant (Valvular) Flow Rate by Proximal ConvergenceYoganathan A.P., Cape E.G., Levine R.A., Thomas J.D., Weyman A£. 707

VOLUME II

SESSION MED_US: ULTRASOUNDS IN CARDIOVASCULAR SYSTEM 2

Computational Approaches for Evaluation of Ventricular Wall Motion from 2-DEchocardiogramsBaraldi P., Guidazzoli A, Lambert! C, Prandini A, Sgallari F. 711

Fluid Mechanical Modelling of Mitral Valve EchocardiogramVerdonck P., Segers P., Fronteau C, Verhoeven ft, Missault L., Vandenbogaerde J. 71 5

Left Ventricular Shape Classification Using Parametric ModelingBaroni At, Barletta G., Evangelist! A 719

Parameter Estimation of Vascular Tissue by Ultrasound BackscatterSantarelli M.F., Landini L, Paterni M. 723

Relation between Orientation of Myocardial Fibers and Parameters in UltrasonicsTissue CharacterizationShiina T, Nishimura H., Nakamura T, Takamoto T, Sakamoto T. 7 2 7

Three-Dimensional Echocardiography of the Beating HeartPini ft., Costi At, Akidi G.L, Masotti L, Novins K.L, Greenberg D.P., Devereux R.B. 731

Three-Dimensional Visualization of Velocity Profiles in the Porcine ThoracicDescending AortaPodersen EM, Kim W.Y., Semod L, Hasenkam JM.. Nygaard H. .735