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Prevalence of Depression in Europe - ISPOR | The ... Prevalence of Self-Reported and Medically...
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Chart-1: Prevalence of Self-Reported and Medically Diagnosed Depression within Lifetime Medically-diagnosed Self-reported EHP 2007 / 2008, N = 237,354 patients are treated with prescription medication, majority of medically-undiagnosed depressive individuals remained un-medicated, with only a small proportion reporting OTC medication use. Depression is common concomitant disease of a multitude of ailments. As shown in Chart-4, prevalence of various diseases in individuals suffering from depression is quite higher than those in general panel population. Burden of depression strongly influenced daily activities. The average number of days missed from regular work due to sickness is approximately 2.8 times higher in the depression group compared to the general panel population. Conclusions Prevalence of depression appears to be substantial in the studied European nations and peaked in the 40-60 age group. Females had substantially higher disease burden, amounting to as much as twice as their male counterparts in certain age groups. Observed diagnosis and treatment patterns warrant further scrutiny to devise a holistic disease management strategy to alleviate burden. Methods TNS Healthcare’s European Healthcare Panel of individuals in France, Germany, Italy, UK and the Netherlands was surveyed in 2007 / 2008 to assess disease burden at national level. The self-reported epidemiological data is representative of population gender and age (18-24, 25-34, 35-44, 45-54,5 5-64, 65-69 yrs) strata in respective countries, ensured by sampling and intensive panel management. The survey collected information on select health conditions (incl. depression; in the past 12 months), quality of life and healthcare-utilization. In the TNS European Healthcare Panel, 8,665, 41,360, 29,552, 81,440, 59,881 and 19,107 individuals completed the survey in the Netherlands, Germany, Italy, France, UK and Spain respectively. Results Burden of depression varies by gender and age. Across the studied countries pre- valence of depression is higher in women than in men and both males and females Prevalence of DEPRESSION in Europe A Comparison of Six Countries have the highest risk to suffering from depression in their midlife (40 to 60 years). Irrespective of gender, age and country a large number of individuals who indicated suffering from low mood / depression are not medically diagnosed as such. Overall 17% of individuals in age group 18-69 years reported to suffer from depression / low mood. This amounts to 35,235,000 individuals, who are adversely affected by depressed mood in these six countries. Prevalence of depression is thereby not equally spread across Europe: particularly the British and the Spanish reported more often to be afflicted with depressed feeling or low mood than the other European counterparts in the study. On the contrary, the Dutch reported the lowest prevalence. As depicted in Chart-2, the point of diagnosis of depressive mood varies across the six studied nations: diagnosis by GP was predominant in UK, France and the Netherlands, whereas in Germany, Italy and Spain the primary diagnosis was done by a specialist or a physician at medical care centre. A significant portion of individuals remained medically undiagnosed in the studied geographies. Differences between medically diagnosed and undiagnosed patients are observed in terms of medication use (Chart-3). Whereas the majority of medically diagnosed Introduction The term depression is often used to describe a temporarily low mood or miserable feeling. However, a clinical or major depression is a mental-disorder, which can be characterized as a co-occurrence of low mood, low self-esteem and loss of interest in daily activities and social environment. Signs and symptoms as well as duration of depressive phase vary between individuals. Especially if a depression stays undiagnosed and therefore untreated the risk of committing suicide increases. Objectives Objective of the study was to assess the prevalence of depression among six large European nations and to detect intra-European differences in treatment and medication patterns. 6,151,508 7,121,215 6,049,846 3,298,334 3,963,251 7,024,310 3,937,162 1,051,206 800,618 7,836,468 4,307,451 3,483,509 Netherlands UK Spain Germany France Italy Graphic-1: Prevalence of Depression / Depressive Mood and Total Number of Individuals Suffering from Depression / Depressive Mood and thereof Untreated Total number Thereof untreated EHP 2007 / 2008, N = 237,354 Chart-2: Diagnosis of Depression / Depressive Mood General practitioner / family doctor Specialist / hospital / medical care center Not medically diagnosed (e.g. diagnosed myself / friends) EHP 2007 / 2008, N = 52,569 UK 33% 55% 12% Germany 39% 21% 40% Netherlands 31% 40% 29% France 46% 38% 16% Spain 36% 27% 37% Italy 43% 23% 34% TNS Healthcare, a Kantar Health Company // Siva Narayanan, MS MHS Ph: +1 203 434 9581 Em: [email protected] // Peter Potthoff, MD Ph: +49 (0)89 5600 1370 Em: [email protected] 45 40 35 30 25 20 15 10 5 0 Female Age (years) Age (years) Male 20-24 25-29 30-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 18-19 20-24 25-29 30-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 18-19 Percentages ≥ 8% ≥ 14% ≥ 20% Prevalence of depression / depressive mood Siva Narayanan – TNS Healthcare, a Kantar Health Company, New York, USA Peter Potthoff, Bernd Guether, Claudia Kanitscheider, Inga-Verena Wiebers – TNS Healthcare, a Kantar Health Company, Munich, Germany Chart-4: Prevalence of Selected Disease-Groups Comparison between Total Population and Group of Individuals Suffering from Depression Individuals suffering from depression Total population EHP 2007 / 2008, N = 237,354 0 10 20 30 40 50 60 70 90 80 Ratio Infection diseases 2.1 Metabolism diseases 1.4 Oncological diseases 2.0 Eye diseases 1.7 Musculoskeletal disease 1.6 Urology diseases 1.2 Respiratory diseases 1.7 Mens and womens health 2.0 Skin diseases 1.6 Cardiovascular diseases 1.4 Gastro intestinal diseases 1.9 Central nervous system 2.5 Pain diseases 1.5 Percentages Chart-3: Use of Medications to Treat Depression / Depressive Mood EHP 2007 / 2008, N = 237,354 18,000 16,000 14,000 12,000 10,000 8,000 6,000 4,000 2,000 0 medically diagnosed not medically diagnosed # of Individuals, in ‘000s None Prescription medication OTC, herbal remedy, complementary therapie
Transcript of Prevalence of Depression in Europe - ISPOR | The ... Prevalence of Self-Reported and Medically...
Chart-1: Prevalence of Self-Reported and Medically Diagnosed Depression within Lifetime
Medically-diagnosed Self-reported
EHP 2007 / 2008, N = 237,354
patients are treated with prescription medication, majority of medically-undiagnosed depressive individuals remained un-medicated, with only a small proportion reporting OTC medication use.Depression is common concomitant disease of a multitude of ailments. As shown in Chart-4, prevalence of various diseases in individuals suffering from depression is quite higher than those in general panel population.Burden of depression strongly infl uenced daily activities. The average number of days missed from regular work due to sickness is approximately 2.8 times higher in the depression group compared to the general panel population.
ConclusionsPrevalence of depression appears to be substantial in the studied European nations and peaked in the 40-60 age group. Females had substantially higher disease burden, amounting to as much as twice as their male counterparts in certain age groups. Observed diagnosis and treatment patterns warrant further scrutiny to devise a holistic disease management strategy to alleviate burden.
MethodsTNS Healthcare’s European Healthcare Panel of individuals in France, Germany, Italy, UK and the Netherlands was surveyed in 2007 / 2008 to assess disease burden at national level. The self-reported epidemiological data is representative of population gender and age (18-24, 25-34, 35-44, 45-54,5 5-64, 65-69 yrs) strata in respective countries, ensured by sampling and intensive panel management. The survey collected information on select health conditions (incl. depression; in the past 12 months), quality of life and healthcare-utilization. In the TNS European Healthcare Panel, 8,665, 41,360, 29,552, 81,440, 59,881 and 19,107 individuals completed the survey in the Netherlands, Germany, Italy, France, UK and Spain respectively.
ResultsBurden of depression varies by gender and age. Across the studied countries pre- valence of depression is higher in women than in men and both males and females
Prevalence of DEPRESSION in EuropeA Comparison of Six Countries
have the highest risk to suffering from depression in their midlife (40 to 60 years).Irrespective of gender, age and country a large number of individuals who indicated suffering from low mood / depression are not medically diagnosed as such. Overall 17% of individuals in age group 18-69 years reported to suffer from depression / low mood. This amounts to 35,235,000 individuals, who are adversely affected by depressed mood in these six countries. Prevalence of depression is thereby not equally spread across Europe: particularly the British and the Spanish reported more often to be affl icted with depressed feeling or low mood than the other European counterparts in the study. On the contrary, the Dutch reported the lowest prevalence.
As depicted in Chart-2, the point of diagnosis of depressive mood varies acrossthe six studied nations: diagnosis by GP was predominant in UK, France and theNetherlands, whereas in Germany, Italy and Spain the primary diagnosis was done by a specialist or a physician at medical care centre. A signifi cant portion of individuals remained medically undiagnosed in the studied geographies.Differences between medically diagnosed and undiagnosed patients are observed in terms of medication use (Chart-3). Whereas the majority of medically diagnosed
IntroductionThe term depression is often used to describe a temporarily low mood or miserable feeling. However, a clinical or major depression is a mental-disorder, which can be characterized as a co-occurrence of low mood, low self-esteem and loss of interest in daily activities and social environment. Signs and symptoms as well as duration of depressive phase vary between individuals. Especially if a depression stays undiagnosed and therefore untreated the risk of committing suicide increases.
ObjectivesObjective of the study was to assess the prevalence of depression among six large European nations and to detect intra-European differences in treatment and medication patterns.
6,151,508
7,121,215 6,049,846
3,298,334
3,963,251
7,024,3103,937,162
1,051,206800,618
7,836,4684,307,451
3,483,509
NetherlandsUK
Spain
Germany
France
Italy
Graphic-1: Prevalence of Depression / Depressive Mood and Total Number of Individuals Suffering from Depression / Depressive Mood and thereof Untreated
Total numberThereof untreated
EHP 2007 / 2008, N = 237,354
Chart-2: Diagnosis of Depression / Depressive Mood
General practitioner / family doctor
Specialist / hospital / medical care center
Not medically diagnosed(e.g. diagnosed myself / friends)
EHP 2007 / 2008, N = 52,569
UK
33%
55%
12%
Germany
39%
21%
40%
Netherlands
31% 40%
29%
France
46% 38%
16%
Spain
36%27%
37%
Italy
43%
23%
34%
TNS Healthcare, a Kantar Health Company // Siva Narayanan, MS MHS Ph: +1 203 434 9581 Em: [email protected] // Peter Potthoff, MD Ph: +49 (0)89 5600 1370 Em: [email protected]
45
40
35
30
25
20
15
10
5
0
Female
Age (years) Age (years)
Male
20-2
425
-29
30-3
435
-39
40-4
445
-49
50-5
455
-59
60-6
465
-69
18-1
920
-24
25-2
930
-34
35-3
940
-44
45-4
950
-54
55-5
960
-64
65-6
918
-19
Per
cent
ages
≥ 8%≥ 14%≥ 20%
Prevalence of depression / depressive mood
Siva Narayanan – TNS Healthcare, a Kantar Health Company, New York, USAPeter Potthoff, Bernd Guether, Claudia Kanitscheider, Inga-Verena Wiebers – TNS Healthcare, a Kantar Health Company, Munich, Germany
Chart-4: Prevalence of Selected Disease-GroupsComparison between Total Population and Group of Individuals Suffering from Depression
Individuals suffering from depression Total population
EHP 2007 / 2008, N = 237,354
0 10 20 30 40 50 60 70 9080
Ratio
Infection diseases 2.1
Metabolism diseases 1.4
Oncological diseases 2.0
Eye diseases 1.7
Musculoskeletal disease 1.6
Urology diseases 1.2
Respiratory diseases 1.7
Mens and womens health 2.0
Skin diseases 1.6
Cardiovascular diseases 1.4
Gastro intestinal diseases 1.9
Central nervous system 2.5
Pain diseases 1.5
Percentages
Chart-3: Use of Medications to Treat Depression / Depressive Mood
EHP 2007 / 2008, N = 237,354
18,000
16,000
14,000
12,000
10,000
8,000
6,000
4,000
2,000
0
medically diagnosed not medically diagnosed
# of
Indi
vidu
als,
in ‘0
00s
NonePrescription medication OTC, herbal remedy, complementary therapie
