Presented by: Dane Smith, DDS Medical Emergencies in the Dental Office.
-
Upload
cathleen-hodges -
Category
Documents
-
view
217 -
download
2
Transcript of Presented by: Dane Smith, DDS Medical Emergencies in the Dental Office.
Nitrogen, CO2, etc.
Atmospheric Pressure20% O2
Airway
Lungs
Veins Arteries
Tissues
Mitochondria
ATP - ADP
H2O/CO2Carbon-based moleculesO2
Clinical manifestations of local-anesthetic overdoseSigns Symptoms Low to Moderate overdose levels
Confusion Headache
Talkativeness Light headedness
Apprehension Dizziness
Excitedness Blurred Vision, unable to focus
Slurred speech Ringing in ears
Generalized Stutter Numbness of tongue & perioral tissues
Muscular twitching and tremor of the face Flushed or chilled feeling
And extremities Drowsiness
Nystagmus Disorientation
Elevated blood pressure Loss of consciousness
Elevated heart rate
Elevated respiratory rate
Moderate to High overdose levels
Generalized tonic-clonic seizure, followed by:
Generalized CNS depression
Depressed blood pressure, heart rate and respiratory rate
0.4 4 7.2
0.5 5 9
1 10 18
1.5 15 27
2 20 36
3 30 54
4 40 72
Miligrams of local anesthetic per cartridge (1.81 ml) commonly used in dentistry
% Total
Concentration = mg/ml x 1.8 ml = mg/cartridge
PatientWeight (lb)
Lidocaine2% with/withoutVasoconstrictor;2.0 mg/lbUp to 300 mg max
CarbocaineMepivacaine2% or 3% with or without vasoconstrictor2.0 mg/lbUp to 300 mg max
CitanestPrilocaine4% with/withoutVasoconstrictor 2.7 mg/lbUp to 400 mg max
SeptocaineArticaine (for adults)4% withVasoconstrictor; 3.2 mg/lbUp to 500 mg max
SeptocaineArticaine (for kids)4%Vasoconstrictor; 2.3 mg/lbUp to 500 mg max
Mg No. of cartridges
Mg No. of cartridges
Mg No. of cartridges
Mg No. of cartridges
Mg No. of Cartridges
Maximal recommended doses of commonly used local anesthetics
2% 3%
20 40 1.1 40 1.1 0.8 54 0.75 64 0.9 46 0.6
40 80 2.2 80 2.2 1.5 108 1.5 128 1.8 92 1.3
60 120 3.3 120 3.3 2.0 162 2.25 192 2.7 138 1.9
80 160 4.4 160 4.4 3.0 216 3.0 256 3.6 184 2.5
100 200 5.5 200 5.5 3.5 270 3.75 320 4.4 230 3.0
120 240 6.5 240 6.5 4.0 324 4.5 384 5.33
140 280 7.5 280 7.5 5.0 378 5.0 448 6.2
160 300 8.0 300 8.0 5.5 400 5.5 500 7.0
180 300 8.0 300 8.0 5.5 400 5.5 500 7.0
200 300 8.0 300 8.0 5.5 400 5.5 500 7.0
Mg
No. of Cartridges
Marcaine
.5% w 1:200,000 epi
90 mg max
From S. Malamed
9 mg /10 lbs
Of body wt
Not to exceed
10 c
100 lbs
10 = 2.5c
4
100 lbs 10 = 2.5c
4
100 lbs 10 = 3.3c
3
100 lbs 10 = 5c
2
100 lbs
320 mg = 4.7c
68 mg/c
100 lbs 400 mg = 5.5c
72 mg/c
100 lbs 300 mg = 5.5c
54 mg/c
100 lbs 320 mg = 8.8c
36 mg/c
Septaocaine
4% w, 1:100,000 epi
Children/Adults
3.2 mg/lb
Citamest
4% w/1:200,000 epi
4.0 mg/lb
600 mg max
Carbocaine
3% w/
vasoconstrictor
3.0 mg/lb
400 mg max
Lidocaine
2% w/ 1:100,000 epi
3.2 mg/lb
500 mg max
Dane’s Rule
Package Insert
Marcaine
.5% w 1:200,000
90 mg max
Maricaine .5%
9 mg/c
* c= carpules
Lidocaine 2% w 1/100,000 epi
Carbocaine 3%W vasoconstrictor
Citanest 4%w 1/200,000 epi
Septocaine 4%w 1/100,000 epiFor kids
Malamed 100lbs Max5.5 c 8.3c
100lbs Max3.5c 5.3c
100lbs Max3.75c 5.5c
100lbs Max3.0c 7.0c
Insert 8.8c 13.8c 5.5c 7.4c
5.5c 8.3c 4.7c 6.9c
Dane’s Rule 5c 3.3c 2.5c 2.5c
Comparables for 100lbs
Marcaine .5%w 1/200,000 epi
9mg/1lbs
1c/10lbs10c max
Mepivacaine 500 4.7 3.0
Lidocaine 400 4.3 3.0
Prilocaine 400 2.8 2.6
Etidocaine 300 1.4 1.3
Effects of vasoconstrictor (epinephrine 1 : 200,000) on peak local anesthetic level in blood
Local Anesthetic
Dose(mg)
Peak Level (ug/ml
without vasoconstrictor
with vasoconstrictor
From S. Malamed
Epinephrine 1 : 50,000 Healthy adult .2 mg Lidocaine 2%
1 : 100,000 Cardiac patient 0.04 mg Articaine 4%
1 : 200,000 Lidocaine 2%
Articaine 4%
Prilocaine 4%
Levonordefrin 1 : 20,000 Healthy adult 1.00 mg Mepivacaine 2%
Cardiac patient 0.2 mg Procaine 2% with
propoxycaine 0.4%
Levarterenol 1 : 30,000 Healthy adult 0.34 mg Procaine 2% with
(Levophed) Cardiac patient 0.14 mg propoxycaine 0.4%
Vasoconstrictor commonly employed in dentistry
Agent Available Maximal Local Anesthetic concentrations dose agents used with
From S. Malamed
1:1000 Epinephrine 1.0 Not Applicable Not available in local anesthetic cartridges
(emergency kit)
1:10,000 Epinephrine 0.1 Not Applicable Not available in local anesthetic cartridges
(emergency kit)
1:20,000 Levonordefrin 0.5 0.09 10 (H), 2 (C)
1:30,000 Levarterenol 0.034 0.06 5(H), 2 (C)
1:50,000 Epinephrine 0.02 0.036 5(H), 2 (C)
1:100,000 Epinephrine 0.01 0.018 10 (H), 2 (C)
1:200,000 Epinephrine 0.005 0.009 20 (H), 4 (C)
Drug mg per maximum no. of cartridgesDilution available mg/ml cartridge (1.8 ml) used for healthy patient (H) and for cardiac patient (C)
Dilutions of vasoconstrictor used in dentistryFrom S. Malamed
Dose .125 mg .3 mg
Epinephrine
Lungs
Heart Arteries
Beta 2 Beta 1 Alpha
Bronchodilation
Oxygen Availability
1. Heart Rate
2. Contractility
3. Centralized Perfusion
4. Counteracts effects of histamine
Blood Pressure
Vascular Resistance
Peripheral Vascular Constriction
Pain
Non-Narcotics
1. Side effects
2. Drug interactions
Acetaminophen
Ibuprophen
Aspirin
Narcotics
Nitrous Oxide
Codeine
Hydrocodiene (vicodin)
Oxycodone (percodon)
Potential Medical Concerns Potential Medical Concerns Potential Medical Concerns
1. Side effects
2. Drug interactions
1. Side effects
2. Drug interactions
Antibiotics
Penicillins
CephalosporinsBiaxin
1. Dosage & Frequency
2. Potential Medical Concerns
3. Side Effects
4. Drug Interactions
ErythromycinsClindamycins
Tetracyclines