PANTROFINA® REMEDY A TRANSVERSAL QUENCHING RELIEF

PANTROFINA® REMEDY :

A TRANSVERSAL RELIEF ACTIVE INGREDIENT

Pantrofina® Remedy transversal quenching relief

A complex of active ingredients:• high efficacy against dandruff and skin

itchiness• antibacterial properties• fast and effective quencher of

inflammation

the best answer when scalp or skin are subjected to stressful situations that affect skin homeostasis.

Inci: Propylene Glycol (and) Undecylenic Acid (and) Arginine (and) Salicylic Acid

MANDALA A TRANSVERSAL BEAUTY

Body

Mind

Spirit

Emotions

Harmony

WELLNESS

Our skin is like a complex microcosm, a beautiful Mandala

PANTROFINA REMEDY : A SKIN DISCOMFORT RESCUE,

THE SCALP RELIEF

WHY SCALP?

SCALP CARE : NEW MARKET OPPORTUNITY

Haircare brands still have potential to blur with skincare and emphasise how they can care for the scalp, and in turn improve hair condition.

Scalp care products use trending microbiome-friendly formulas or promote pollution protection benefits for optimal and gentle scalp health.

In France, Germany, Italy and Spain, 75-85% of women agree that caring for the scalp can improve hair condition; yet few products make reference to scalp care.

Gap in the market for a dedicated scalp care segment

18%of haircare launches in

Europe in the 12 months

to April 2019 made

reference to scalp care

Read on mintel.com

SKINIFICATION OF HAIR CARE

POLLUTION PROTECTION

Consumers are showing interest in hair products containing ingredients that have trended in facial skincare.

INGREDIENTS COMMONLY USED IN SKINCARE SHOW INTEREST FOR HAIR

Base: Internet users aged 16+ who have used haircare/hair styling products in the last 12 months - France (1954); Germany (1958); Italy (1974); Spain (1986) Source: Lightspeed/Mintel

SCALP CARE : NEW MARKET OPPORTUNITY LINKED TO

POLLUTION AND SUSTAINABILITY

Exposure to polycyclic aromatic hydrocarbons (PAHs) in people living in urban and rural areas as revealed by hair analysisChemosphereVolume 246May 2020Article 1257641.Chunhui Wang, Shenglu Zhou, Shaohua Wu, Junhong Tang

Toxins (Basel). 2017 Dec 27;10(1). pii: E14. doi: 10.3390/toxins10010014.Human Scalp Hair as an Indicator of Exposure to the Environmental Toxin β-N-Methylamino-l-alanine.Downing S1, Scott LL2, Zguna N3, Downing TG4.

Which are new consumer needs?

Pantrofina Skin 360: strong antioxidantactive ingredientagainst pollutiondamages.

MoripureOur regenerated Sericin, coming from sustainablesource, with proven anti pollution power. An activeshield from pollution.

Protection from pollution,reducing damages

Do it in a sustainable way

PANTROFINA REMEDY : A SKIN DISCOMFORT RESCUE,

THE SCALP RELIEF

The alteration of microenvironment of scalp lead to several discomfort example : dandruff , dermatitis, itching:

PANTROFINA® REMEDY is the perfect solution for sensitive skin and scalp.

Sebaceous hyperproductionPollution

Alteration of skin micro-floraHormonal diseases

Redness, Itchiness, Skin desquamation, Dandruff, Dermatitis

Inflamation

Develop more standalone scalp care sprays and bring an element of convenience and ease of use.

Aveda Rinseless Refresh Micellar Hair & Scalp Refresher

IGK Trust Issues Instant Scalp Rebalancing Treatment

Read on mintel.com

Dr. Organic's Coffee Hair & Scalpcollection, available in Anti-Dandruff and Stimulating (hair growth) variants uses caffeine in its formulation to help energise the scalp and hair.

The Stimulating line includes protein-packed guarana, intense chilli, ginger, lemongrass, black pepper and nettle.

Use stimulating ingredients to boost scalp circulation

SCALP CARE : NEW MARKET OPPORTUNITY

IGK Trust Issues Instant

Scalp Rebalancing Treatment

uses a patented Hydrogel

time-release technology to

moisturise the scalp both

instantly and over time.

Aveda's Rinseless Refresh

Micellar Hair & Scalp Refresher

with Babassu-derived micelles

offers an alternative to dry

shampoo, and attracts and lifts

impurities leaving the scalp clean

in an instant.

PANTROFINA® REMEDY : ANTI-DANDRUFF IN VIVO TEST

The anti-dandruff study was carried out

on 20 male and female subjects with dry or oily dandruff whosuffered from itchiness. The aim of the study was to evaluate the effect of the product on the reduction of dandruff and cutaneous itching after 7 and 28 days of application

INCI %

Water AQUA

QB TO

100RESASSOL C35 DISODIUM COCOYL GLUTAMATE 5

COCO-GLUCOSIDE 5

RESASSOL

APOSTROPHIE

CAPRYLYL/CAPRYL GLUCOSIDE (AND) WATER (AND)

POLYGLYCERYL-3 COCOATE (AND) POLYGLYCERYL-10 LAURATE

(AND) CITRIC ACID 4RESPLANTA

MACADAMIA

MB MACADAMIA SEED OIL GLYCERETH-8 ESTERS 3PANTROFINA

REMEDYPROPYLENE GLYCOL (AND) UNDECYLENIC ACID (AND)

ARGININE (AND) SALICYLIC ACID 1Phenoxyethanol, Benzoic Acid, Dehydroacetic Acid,

Ethylhexylglycerin 1,2

COCAMIDOPROPYLHYDROXYSULTAINE, Water 14

20PS03 Remedy Effective Shampoo

Aveda RinselessRefresh Micellar Hair & Scalp Refresher

PANTROFINA® REMEDY : ANTI-DANDRUFF IN VIVO TEST

The effect of treatment was evaluated on the reduction of dandruff and cutaneous itching after 7 and 28 days of application

The decrease of dandruff amount has been evaluated through acquisition of micro-tricographic images by Dino Lite

Pictures taken at the beginning of the treatment(T0) and after 7 and 28 (T7 and T28) days of application

PANTROFINA® REMEDY : ANTI-DANDRUFF IN VIVO TEST

PANTROFINA® REMEDY showed to be highly effective on decreasing

dandruff in only 7 days for the 80% of panelists.

% of subjects who don’t show a dandruff decrease% of subjects who show a dandruff decrease

Percentage of subjects who show a clinical improvement of the dandruff amount.

PANTROFINA® REMEDY : SCALP ITCHING QUENCHER

The efficacy against itching and skin tolerability was evaluated through a score value given by a visual analogue VAS (Visual Analogue Scale) scale

PANTROFINA® REMEDY : SCALP ITCHING QUENCHER

Each volunteer was asked to assign a value related to a level of scalp itching both at the beginning (T0) and at 7 and 28 daysof treatment (T7 and T28) using the following scale:

0= No itching1= Slight itching2= Moderate itching3= Severe itching

highly efficacy on decreasingscalp itching in only 7 days!

INSTANT RESULTLONG-TERM RESULT

PANTROFINA® REMEDY : ANTI-BACTERIAL PROPERTIES

Recommended Use:Level 0.5 – 1.2 % max

Physical Appearance:Clear yellowish liquid.

Solubility: Pantrofina Remedy is easily soluble in glycol, alcohol, surfactant system.In water solution Pantrofina Remedy gives transparency if premixed in a ration 1:1 with Resassol VS.

Formulation tips:In a cleansing formulation, add Pantrofina Remedy in the primary surfactant. In an emulsion, add Pantrofina Remedy at the end, under 35°C.

pH finished products : 4.5 -5.5

Pantrofina® Remedy MIC for Malassezia Furfur is approximately 1%

Pantrofina® Remedy: MIC

Determination against Malassezia Furfur

The antibacterial efficacy allows to limit the amount of preservative in the formulation assuring microbiology safety

Toxicology:Skin Irritation: Dermal Mild Irritant (Dermal IrritectionAssays)Eye Irritation: Ocular Moderate irritant (Ocular IrritectionAssays)

PANTROFINA® REMEDY : AN EXAMPLE OF EMULSION

20P12_CRE_01 TRULY HYDRATION CREAM

Commercial Name

Phase A

WATER

GLYCERIN

TRIACETIN

Phase B

CETEARYL ALCOHOL 50:50

EMULPHARMA® CHROMA

Phase C

WATER

UREA

Phase D

PANTROFINA® REMEDY

PRESERVATIVE

PERFUME

%

49,8

5

3

5

5

20

10

1

1

0,2

Physical-Chemical Data:Appeareance: Consistent Gel EmulsionpH: 5,3 - 5,8

INCI name

AQUA

GLYCERIN

TRIACETIN

CETEARYL ALCOHOL

LAURYL ALCOHOL, C12-14 PARETH-5, MYRISTYL ALCOHOL, C12-15 PARETH-3 PHOSPHATE, CETETH-2

AQUA

UREA

PROPYLENE GLYCOL (AND) UNDECYLENIC ACID (AND) ARGININE (AND) SALICYLIC ACID

PHENOXYETHANOL, ETHYLHEXYLGLYCERIN

PARFUM

A rich and moisturizingcream, easy to be adsorbed

Moisturizing, thanks to 10% of urea

Pantrofina Remedyoffers an anti-bacterialpower for a long lasting protection.

Emulpharma Chroma, allows to formulate rheologic free emulsions.

PANTROFINA® REMEDY : RESULTS

PANTROFINA® REMEDY : APPLICATION AND CLAIMS

APPLICATION

SCALP CAREOILY SKIN BEAUTYROUTINESENSITIVE SKINAnti-bacterial products ANTI-AGE CREAMDYESAFTER SHAVE

CLAIMS

ANTI DANDRUFFSOOTHINGANTI-ITCHINESSSKINIFICATION OF HAIRCAREHEALTHY AGEINGINSTANT RESULTLONGTERM RESULT

Pantrofina Remedy Inci: Propylene Glycol (and) Undecylenic Acid (and) Arginine (and) Salicylic Acid

China listedPalm oil free Vegan

PANTROFINA REMEDY : A SKIN DISCOMFORT RESCUE,

THE SCALP RELIEF

QUESTIONS ?

Designed to give fast response to skin and scalp

deseases

Pantrofina Remedy

Inci: Propylene Glycol (and) Undecylenic Acid (and) Arginine (and) Salicylic Acid

THANK YOU