Presentation2
-
Upload
roz-aboalkhair -
Category
Engineering
-
view
77 -
download
0
Transcript of Presentation2
![Page 1: Presentation2](https://reader030.fdocuments.in/reader030/viewer/2022032504/55c3aafabb61eb674d8b456d/html5/thumbnails/1.jpg)
PRESENT BY
ROZANA ABOALKHAIR
GLUCOSE NANOSENSOR TATTOO
![Page 2: Presentation2](https://reader030.fdocuments.in/reader030/viewer/2022032504/55c3aafabb61eb674d8b456d/html5/thumbnails/2.jpg)
OVERVIEW
• INTRODUCTION
• GLUCOSE NANOSENSOR TOOLS
i- INJECTOR
ii-NANOSENSOR TATTO
iii- IMAGING DEVICE
• CONCLUSION
![Page 3: Presentation2](https://reader030.fdocuments.in/reader030/viewer/2022032504/55c3aafabb61eb674d8b456d/html5/thumbnails/3.jpg)
Diabetes Has Become Epidemic • Every day,
3,600 new cases of diabetes are diagnosed.
580 people die of diabetes-related complications.
225 people have a diabetes-related amputation.
120 people with diabetes progress to end-stage renal disease.
55 people with diabetes become blind.
American diabetes association, May,2012.
![Page 4: Presentation2](https://reader030.fdocuments.in/reader030/viewer/2022032504/55c3aafabb61eb674d8b456d/html5/thumbnails/4.jpg)
GLUCOSE NANOSENSOR TOOLS
• Injector
• Nanosensor tattoo
• Imaging device
Trends in Molecular Medicine, Volume 16, Issue 12, 584-593, 23 September 2010
![Page 5: Presentation2](https://reader030.fdocuments.in/reader030/viewer/2022032504/55c3aafabb61eb674d8b456d/html5/thumbnails/5.jpg)
PLACEMENT IN SKIN
Skin Pharmacol Physiol,2009
![Page 6: Presentation2](https://reader030.fdocuments.in/reader030/viewer/2022032504/55c3aafabb61eb674d8b456d/html5/thumbnails/6.jpg)
PLACEMENT IN SKIN
Skin Pharmacol Physiol,2009
![Page 7: Presentation2](https://reader030.fdocuments.in/reader030/viewer/2022032504/55c3aafabb61eb674d8b456d/html5/thumbnails/7.jpg)
Nanosensors composed of a hydrophobic polymer containing:
• Lipophilic glucose recognition elements
(boronic acid derivatives, PhB(OH)2 )
• Fluorescent reporters. (alizarin, C14H8O4 )
Trends in Molecular Medicine, Volume 16, Issue 12, 584-593, 23 September 2010
NANOSENSOR TATTOO COMPONENTS
![Page 8: Presentation2](https://reader030.fdocuments.in/reader030/viewer/2022032504/55c3aafabb61eb674d8b456d/html5/thumbnails/8.jpg)
Imaging Device
Trends in Molecular Medicine, Volume 16, Issue 12, 584-593, 23 September 2010
![Page 9: Presentation2](https://reader030.fdocuments.in/reader030/viewer/2022032504/55c3aafabb61eb674d8b456d/html5/thumbnails/9.jpg)
CONCLUSION• minimize the need for the implantation of electrochemical sensors , which minimizes
patient inconvenience and pain.
• Can performed when the patient is sleeping.
• Provide a means to measure the glucose levels continuously instead of only specific time.
• It would be an additional cost of producing this smart tattoo, by thoroughly comparing the smart tattoo with other commercially available nanosensors.
• The tattoo, like most cutting-edge technologies have drawbacks, but can be turned around to full efficiency.
![Page 10: Presentation2](https://reader030.fdocuments.in/reader030/viewer/2022032504/55c3aafabb61eb674d8b456d/html5/thumbnails/10.jpg)
Reference • American Diabetes Association. (2012). "Diabetes Basics.”
• Cash, Kevin J., and Heather A. Clark. "Nanosensors and nanomaterials for monitoring glucose in diabetes." Trends in molecular medicine 16.12 (2010): 584-593.
• Card, Jeffrey W., and Bernadene A. Magnuson. "A review of the efficacy and safety of nanoparticle-based oral insulin delivery systems." American Journal of Physiology-Gastrointestinal and Liver Physiology 301.6 (2011): G956-G967.
![Page 11: Presentation2](https://reader030.fdocuments.in/reader030/viewer/2022032504/55c3aafabb61eb674d8b456d/html5/thumbnails/11.jpg)
THANK YOU…