Immunohistochemistry Antibody Validation Report for Anti-Cdk2 Antibody (STJ92197)
Presentation of Michael Mackie in 1st International Antibody Validation Forum 2014
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Transcript of Presentation of Michael Mackie in 1st International Antibody Validation Forum 2014
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A NEW ARTICLE TYPE AND PLATFORM FOR THE
PUBLICATION OF ANTIBODY VALIDATIONS
MICHAEL MARKIEAssociate Publisher, F1000Research
@mmmarksman
f1000research.com@f1000research
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WHAT PUBLISHING SHOULD BE:
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A TYPICAL F1000RESEARCH ARTICLE PAGE:
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THE NEED FOR AN ANTIBODY VALIDATION ARTICLE TYPE?
• Antibodies are among the most common reagents used in research and clinical laboratories
• There is lack of standard guidelines when it comes to manufacturing, validating, and using antibodies
In an ideal world researchers would like:
• Confidence in a particular antibody before it is purchased
• Confidence in the specificity, selectivity and reproducibility
• Information based on actual use cases from the scientific community
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TRYING TO TACKLE THE PROBLEM
1. Viability: costs, incentives, interested parties, potential conflicts
2. Editorial Considerations:
- discussed different types of validations that can be performed - creating a set of flexible guidelines for all validations- Identifying an editorial board
3. Dissemination: creating a permanent, discoverable venue for articles
The Antibody Validation article
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... INTRODUCING THE ANTIBODY VALIDATION COLLECTION
So far we have created:
• A set of author guidelines for validation articles to be published under the F1000Research ‘Research Note’ article type
• A diverse editorial board with a mixture of industry and academia expertise
• A dedicated F1000Research Antibody Validation Collection to host all of the antibody validation articles we receive.
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ANTIBODY COLLECTION PAGE
f1000research.com/article-collections/antibody-validation
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GUEST EDITORS AND EDITORIAL BOARD
Guest Editors: Andrew Chalmers (CiteAb) Matt Helsby (CiteAb) Mei Leung (St John’s Laboratory)
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ARTICLE GUIDELINES
bit.ly/F1R-AV-Guidelines
The article guidelines we devised can be found here online:
There are some here too, please take one!
Your thoughts are more than welcome.
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THE NEXT STEPS
Promoting the new article type and collection to the wider community
Instilling the idea that publishing validations is beneficial and worthwhile
Looking at ways in which we can help grow the content of the collection
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WE WANT TO ENCOURAGE INPUT FROM THE COMMUNITY
Feedback on what we have done to date
Contribute – input will be happily received!
How do we best reach the community?
Are their any potential pitfalls?