PREDICTIVE - PREVENTIVE - PERSONALISED …...innovative technologies and exceptional customer...

PREDICTIVE - PREVENTIVE - PERSONALISEDHEALTHCARE

#108, 1st Floor, Elite Business Center, Al Barsha 1, Dubai, UAE.

Tel: +971 4 325 5730 —

[email protected]

HIGHLY SPECIALIZEDDIAGNOSTIC PRODUCTS

TABLE OF CONTENTS Page No

About Us 3

Highly Specialized Diagnostic Products - Introduction 4

1. Specialized Screening Tests 6a. New Born Screening (NBS) 7b. Insure®FIT™ 8

2. Clinical Genetics 10a. Non Invasive Prenatal Test (TRIGENE) 11b. Parkinson-Alzheimer-Dementia Panel 12c. Diabetes/Obesity Panel 13d. Pan Cardio Panel 14e. Retinal Degeneration Panel 15f. Targeted Mutation Screening 16g. Carrier Screening Test 17h. Inherited Disease Panel 18

3. Clinical Genomics 20a. Whole Exome Sequencing 21b. Whole Genome Sequencing 22

4. Cancer Genetics 24a. BRCA1/2 Full Sequencing with deletion & duplication 25b. BRCAPlus™ 26c. BreastNext™ 27d. ColoNext™ 28e. GynPlus™ 29f. Comprehensive Cancer Panel 30

5. Wellness/Anti Aging/Lifestyle Genetic Tests 32a. Geneus™ 33b. Telomere Test 34c. Karmagenes 35d. SkinCareDNA 36e. Fitness & Diet Genetic Test 37f. GPL SNP1000 38

6. Wellness/Anti Aging/Lifestyle Non Genetic Tests 40a. Food Intolerance Test (FOODWatch) 41b. Food Allergy Test 42c. Executive Wellness Profile 43d. Organic Acid Test 44e. Comprehensive Stool Analysis 45f. Gluten/Casein Peptides Test 46g. Weight Management Profile 47h. Skin Vitality Profile 48i. Sleep Balance Profile 49j. Adrenal Stress Profile 50k. Fertility Profile 51l. Cardio Metabolic Profile 52m. Neurotransmitters 53n. Urine Hormones Metabolites 54o. Metals Hair Test 55

7. Counseling Services 58a. Genetic Counseing 59b. Nutritional Counseling 60

ABOUT US

MISSION: To provide a diagnostic service with superlative standards of Efficiency, Ethics and Quality at an affordable cost

VISION: To be the leading provider of affordable diagnostic services in the region

VALUES: • An Obsession with Quality• Ethical in all areas of work• Outstanding customer service that exceeds expectations

GOALS: • Regional and International expansion in the field of medical diagnostic services and developing a strong collaborative partner network to exponentially increase the client base• To build an unmatched reputation in the healthcare sector

Eastern Biotech & Life Sciences is a Medical Diagnostic Services company based in Dubai Science Park. The company has been in operation for over 10 years and has been at the forefront of Diagnostic healthcare in the region. It was established to bring a paradigm shift in the diagnostic industry in the MENA region through adoption of innovative technologies and exceptional customer service. Eastern Biotech and Life Sciences started with a goal of providing predictive and personalized healthcare, the company filled the niche in the highly specialized diagnostic and emerging genetic testing market. Upon achieving a leading market position and regional brand recognition, the company incorporated routine diagnostic testing to its portfolio by setting up its own diagnostic laboratory in Barsha, Dubai and developed a web portal offering all diagnostic tests on B2B and B2C platforms.

The combined Eastern Group of Companies that includes Eastern Biotech and Eastern Clinical Laboratories now offers its services through various channels which include partner laboratories, clinics, hospitals independent doctors, and a ‘Direct-to-Customer’ web portal. The experience gained so far has also allowed us to enhance our services to include Quality and Accreditation support and Project Management for the setting up and commissioning of new laboratories.

Our team of highly qualified and hard working professionals anticipates the future with a renewed sense of enthusiasm to go beyond the ordinary to become an exceptional provider of diagnostic services and to grow beyond the region into the global market.

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HIGHLY SPECIALIZED PRODUCTS

The definition of a genetic test has changed as the applications have evolved

The circumstances of the individual genetic test - including the acute nature of the phenotype, the age of the

patient, family history and specimen availability - guide the selection of tests and test platforms

Our highly specialized test offerings have been carefully hand picked to meet quality, time, technology, & cost

needs of our clients

The portfolio contains clinical testing applications that span medical disciplines, including & not limited to:

Predictive Genetic Tests, Personalized Genetic Tests, Specialized Immunological Tests, Anti Aging & Wellness

Specialty Profiles

Below are some of our featured products in each category

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1.SPECIALIZED SCREENING TESTS Screening tests are laboratory tests that help to identify people with increased risk

for a condition or disease before they have symptoms or even realize they may be at

risk so that preventive measures can be taken. Screening tests help detect disease in

its earliest and most treatable stages. They should be sensitive - that is, to correctly

identify those individuals who have a given disease. Many routine tests performed at

regular health exams are screening tests such as Cholesterol testing and Pap smears

for women. Newborns are screened for a variety of conditions at birth.

• New Born Screening (NBS) • Insure®FIT™

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New Born Screening (NBS) Description: Newborn screening identifies babies with treatable

congenital disorders to prevent adverse outcomes. All of the disorders on the newborn screening panel can be detected by a blood spot collected on filter paper after 24 hours but within 48 hours of birth.

Application(s): •Early diagnosis helps immediate treatment before the baby becomes sick. Usually the affected babies are treated by modification of the diet and/or avoidance of fasting. If the baby requires a repeat test more information will be given about the specific disorder which is suspected. Without appropriate management, some disorders can cause severe disability or death

Technique: Various Immunological Techniques

Sample Type: Blood Spot on filter paper

TAT: 7-10 days

Sample Report: http://www.easternbiotech.com/reports/NBS.pdf

Within 24-48 hours of birth, find hidden disorder or condition in your new born that needs early treatment.

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Insure®FIT™Description: InSure® FIT™ is a CLIA waived test that is available for

Physician Office Lab (POL) testing. To help improvecolorectal cancer screening compliance, InSure®FIT™ screening test offers high sensitivity and ease of use. It is a highly patient-friendly water-Based collection method. It’s patented brush sampling replaces unpleasant fecal collection or smearing and there are no dietary or medication restrictions. InSure® FIT™ has 87% sensitivity for colorectal cancer & 98% specificity. The test has a 66% increase in patient compliance versus a guaiac-based fecal occult blood test (gFOBT) based on a recent study1.

Application(s): Physicians should talk to their patients about starting colorectal cancer screening earlier and/or being screened more often if they have any of the following colorectal cancer risk factors:• Personal history of colorectal cancer or adenomatous

polyps • Personal history of chronic inflammatory bowel disease

(Crohn’s disease or ulcerative colitis) • Strong family history of colorectal cancer or polyps (cancer

or polyps in a first-degree relative [parent, sibling, or child] younger than 60 or in 2 or more first-degree relatives of any age)

• Known family history of hereditary colorectal cancer syndromes such as familial adenomatous polyposis (FAP) or hereditary non-polyposis colon cancer (HNPCC)

Technique: Proprietary technology

Sample Type: Stool in filter paper

TAT: Less than 10 minutes

Sample Report: http://www.easternbiotech.com/reports/IF.pdf

A colorectal cancer screening test that your patient may actually use

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2. CLINICAL GENETICSIn general, Genetic testing refers to the examination of specific bits of DNA that have a known function, usually in a

protein-coding gene. Genetic testing requires that an investigator know which gene or genes to look at, based on some

prior understanding of the underlying biological contribution to a trait or disease.

Clinical (Medical) genetics is the branch of medicine that involves the diagnosis and management of hereditary disorders.

It also refers to the application of genetics to medical care such as diagnosis, management, and counselling people with

genetic

disorders would be considered part of medical genetics.

• TRIGENE Non Invasive Prenatal Test • Parkinson-Alzheimer-Dementia Panel • Diabetes/Obesity Panel • Pan Cardio Panel• Retinal Degeneration Panel• Targeted Mutation Screening • Carrier Screening Test• Inherited Disease Panel

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TRIGENENon Invasive Prenatal Test

Description: Non Invasive Prenatal Testing (NIPT) involves a simple blood test that analyzes cell-free DNA, or cfDNA in maternal blood to pinpoint baby’s risk for a number of genetic disorders including Down syndrome. NIPT is a screening test, which means it’s not “diagnostic”. However it tells you the likelihood of your baby having a disorder. But even though it can’t tell for sure whether your baby has a genetic abnormality, it is highly accurate. The results can help you and your doctor decide next steps, including whether invasive diagnostic tests — which are even more precise but slightly increase the chance of miscarriage — are worth the risk. The screening test can be done as early as 10 Weeks of pregnancy.

Application(s): •The Test is clinically validated for use in pregnant women, of any age or risk category, to assess the risk of fetal trisomy 21 (Down syndrome), trisomy 18 (Edwards Syndrome), & trisomy 13 (Patau syndrome), and other common X & Y chromosomal conditions.

Technique: Microarray with proprietary DNA-based methodology

Sample Type: 10mL Maternal Peripheral blood

TAT: 10-14 Business Days

Sample Report: http://www.easternbiotech.com/reports/NIPT.pdf

Did you know that pieces of your baby’s DNA circulate in your bloodstream? A simple blood test can tell doctors more about your baby than ever before.

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Parkinson’s/Alzheimer’s/Dementia Panel

Description: There are numerous genes associated with Dementia, Alzheimer's and Parkinson's disease. While some of them present particular manifestations that might aid an accurate diagnosis, most of the time, the clinical presentation exhibits common characteristics, making difficult to establish a precise diagnosis. Evidence shows that the conditions are the result of a combination of genetic and environmental factors. In the general population, the risk to develop any of these conditions is estimated to be at least 10%. This risk at least doubles for people with an affected first degree relative. The risk can be estimated more precisely when the genetic cause is known, given that some mutations might confer a higher risk, including early onset presentations. Learning about the genetic risk for these conditions might be of utility for making informed decisions related to medical management and care of a patient and to identify who among the direct family members is at higher or at lower risk.

Application(s): •Considering the significant overlap between the different types of dementia, Alzheimer and Parkinson, identifying the underlying genetic cause can often help to clarify the diagnosis, guide the development of a personalized medical management plan, and avoid unnecessary or ineffective treatments. Learning about the genetic cause of the condition also allows at-risk family members the option to have genetic testing to determine if they may have the condition and/or if they would benefit from additional medical management.

Technique: NGS (Full sequencing with del/dup)

Sample Type: Whole Blood

TAT: 4-6 weeks

Sample Report: http://www.easternbiotech.com/reports/APDMR.pdf

In the general population, the risk to develop Parkinson’s/Alzheimer’s/Dementia is estimated to be at least 10%

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Diabetes/Obesity Panel Description: Diabetes is a group of not well-understood disorders

characterized by abnormal glucose levels. As a complex disease, diabetes is the result of the interplay between the individual’s genetic make-up and the environment and there are multiple genes that are known to be associated with this condition; thus, a multigene panel represents a cost-effective option to identify the genetic cause of diabetes.

Application(s): •The clinical utility of genetic testing for diabetes is based on its capacity to confirm the diagnosis and predict the general clinical course of the condition.

•While a deregulated level of glucose is the common trait for all cases of diabetes, some genetic defects will result in additional manifestations such as macrovascular complications or metabolic syndrome. Identifying the subset of patients who are at higher risk for these or other complications, enables preventive interventions to reduce the negative impact in the patient’s lives.

•Besides improving the management of the individual, discovering of the genetic cause of diabetes in a family allows the identification of family members at risk even before the condition manifests.

•Given the genetic heterogeneity, a multigene panel provides a cost-effective (time and money) alternative that provides an answer in a shorter time and at a lower price.

Technique: NGS


TAT: 5-7 Weeks

Sample Report: http://www.easternbiotech.com/reports/DOSR.pdf

Have you wondered how you developed diabetes? Do you worry that your children will develop it too?

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Pan Cardio PanelDescription: The Pan Cardio Panel is a comprehensive genetic

diagnostic tool developed to cover a wide spectrum of heart related conditions, including arrhythmias and cardiomyopathies. While there are some heart conditions that have an identifiable clinical presentations, some tend to exhibit a heterogeneous phenotype with different responses to specific treatments. Learning the genetic cause of a condition enables clinicians to develop a personalized management plan for each of their patients.

Application(s): •Genetic testing allows the identification of the genetic cause of conditions including hearth disease. Identifying the underlying genetic cause can often help to clarify the diagnosis, guide the development of a personalized medical management plan, and avoid unnecessary or ineffective Treatments. Learning about the genetic cause of the condition also allows at-risk family members the option to have genetic testing to determine if they may have the condition and/or if they would benefit from additional medical management.



TAT: 3-4 weeks

Sample Report: http://www.easternbiotech.com/reports/PCNP.pdf

Do you have a family history of heart problems? Identify the mutated gene causing the disease

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Retinal Degeneration PanelDescription: Mutations in more than 60 genes are known to cause

nonsyndromic retinitis pigmentosa. Mutations in any of the genes responsible for retinitis pigmentosa lead to a gradual loss of rods and cones in the retina. The progressive degeneration of these cells causes the characteristic pattern of vision loss that occurs in people with retinitis pigmentosa. Rods typically break down before cones, which is why night vision impairment is usually the first sign of the disorder. Daytime vision is disrupted later, as both rods and cones are lost. Retinitis pigmentosa often has an autosomal dominant, or autosomal recessive , or X-linked pattern.

Application(s): •Inherited eye disorders are important causes of vision loss. It is desirable to obtain genetic diagnoses for patients with these disorders, as this information can influence patient care by both informing genetic risk assessment and identifying patients who would benefit from novel gene-based therapies

Technique: NGS (Full sequencing)


TAT: 6-8 weeks

Sample Report: http://www.easternbiotech.com/reports/ RDPG.pdf

Retinitis Pigmentosa is the most common inherited cause of blindness in people between the ages of 20 and 60 worldwide (source: http://artificialretina.energy.gov/diseases.shtml)

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Targeted Mutation Screening Description: The test identifies the mutated gene or genes causing

a genetic disease in your family. The identification of a gene mutation(s) allows for further steps to be taken to prevent the passing on of the condition to future generations and may aid in the improvement of treatment of an affected individual.

Application(s): •Mutation screening for a known mutation such as Thalassemia, Sickle cell Anemia, Spinal Muscular Atrophy, Sanjad Sakati and more.

•Screening can be done for any other known mutation as well

•You have the genetic report of a family member and would like to be screened for the same mutation.

•The gene causing the genetic condition affecting your family is of small size (less than 5 exons). •Examples include Beta Thalassemia, Connexin 26

(hearing loss) and more.

Technique: Sanger


TAT: 6-8 business days

Sample Report: http://www.easternbiotech.com/reports/ TMS.pdf

Also known as Familial Mutation Testing, It is used as a diagnostic testing for specific conditions when one or more mutations have been identified in a family member

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Carrier Screening Test Description: Carrier screening analyzes 571 unique genes for

mutations that are known to cause 210 genetic conditions encompassing more than 400 genetic diseases. The majority of the conditions included in Carrier Screening are inherited in an autosomal recessive pattern.

Application(s): •Recommended in cases of consanguineous marriage, history of any genetic condition in the family

•Test allows future parents to find out if they are a carrier for a genetic disorder

•Carrier screening is performed for genetic diseases that are inherited in an Autosomal Recessive or X-linked manner

•Can also identify genetic disorders in people of a particular ethnicity

Technique: NGS (Full Sequencing)


TAT: 4-5 weeks

Sample Report: http://www.easternbiotech.com/reports/CS.pdf

Identify what mutations you and your partner could have, get carrier screening before pregnancy to understand your options earlier on!

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Inherited Disease Panel Description: Broad genetic survey test for investigating general

susceptibility and/or carrier condition for the included Mendelian disorders. 300 genes associated with >700 inherited diseases, including neuromuscular, metabolic, cardiovascular, and developmental diseases.

Application(s): •Pre-conceptional test for couples – Testing done before trying for a baby to understand if there is any risk of passing any inherited disease(s) to the baby.

•Genetic screening of gamete donors•The test can be done by a patient who is concerned

about family history or a particular disease

Technique: NGS (Full Sequencing)


TAT: 4-5 Weeks

Sample Report: http://www.easternbiotech.com/reports/ IDP.pdfHave an inherited genetic condition or disease? Confirm the diagnosis of the genetic condition and guide yourself to proper disease management.

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3.CLINICAL GENOMICSGenomic testing, on the other hand, looks for variations within large segments across

the entirety of genetic material, both within and outside known functional genes.

Investigators don't usually need to have a target gene in mind or any prior knowledge of

the underlying biology of a trait when doing genomic testing. However, genomic testing

produces large amounts of data that must be processed to tease out genetic variants of

significance to a particular trait.

• Whole Exome Sequencing• Whole Genome Sequencing

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Whole Exome SequencingDescription: Less than 2% of whole genome is known to be

protein-coding region, known as Exome. Over 85% of known genetic variants are within this region. Exome sequencing is selective sequencing of the coding regions of the genome, after the Exome has been efficiently captured.

Application(s): •Whole Exome Sequencing is performed for many different clinical Indications. It offers a more comprehensive coverage of the “known” phenotype-specific genes. The clinical usefulness of varies for different disorders. In the majority of cases, the finding does not alter the clinical management, treatment or prognosis. However, it does allow an end to an expensive and stressful diagnostic odyssey. Reaching a molecular diagnosis allows the clinician to allay the guilt that patients can face in the absence of a firm diagnosis. More importantly, it facilitates genetic counseling and allows for more accurate estimates of recurrence risk in the family. Identification of the molecular etiology allows the clinician to guide subsequent pregnancies, either through prenatal diagnostics or pre implantation genetic diagnosis.

Technique: NGS


TAT: 4-6 weeks

Sample Report: http://www.easternbiotech.com/reports/WES.pdf

One of the most extensive genetic tests available, may help find a genetic cause for you or your child’s signs and symptoms even if previous genetic testing did not!

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Whole Genome SequencingDescription: Human whole genome has approximately 3 billion

base pairs of nucleotides. The first human whole genome sequencing (hWGS) was completed and publisehd in 2001. Since then, hWGS is widely studied in the filed of biomedical science, anthropology, forensics and many more. Individual variations, such as single nucleotide polymorphism(SNP), copy number variation (CNV) and structural variations (SV), can be identified by whole genome re-sequencing.

Application(s): •Clinical application of hWGS is the next step in the progression to complete elucidation of the genomic determinants of a patient’s heritable make-up. WGS can provide insights into known and unknown variations in approximately 95% of the individual’s genome. Hence it substantially increases the volume of detected variants.

Technique: NGS


TAT: 6-8 weeks

Sample Report: Contact us for details

Want to determine your entire DNA sequence at one shot?

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4.CANCER GENETICSOver the past decade, we have witnessed a revolution in sequencing technologies

that has had a profound impact on our understanding of genetics and genome

biology. The next generation sequencing technology (NGS) has thus provided a great

potential in the management and treatment of human health bridging to a new era

of molecular pathology and personalized medicine. Eastern Biotech & life sciences

proudly adds to its portfolio several NEW Cancer Genetic tests that will use the

Next Generation Sequencing (NGS) technology. The cutting-edge technology utilizes

a multi-target approach to detect mutation in specific genes & be able to detect

various cancers.

• BRCA1/2 Full Sequencing with Deletion & Duplication• BRCAPlus™• BreastNext™• ColoNext™• GynPlus™• Comprehensive Cancer Panel

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BRCA1/2 Full Sequencing with Deletion & Duplication

Description: BRCA1 and BRCA2 are tumor suppressor genes that have an essential role in both DNA repair and cell cycle control systems. Germline BRCA1 and BRCA2 mutations are implicated in 25-50% of hereditary breast cancer Cases. The genetic test analyzes the BRCA1 and BRCA2 genes to identify any inherited changes (mutations) in them that can increase the risk for cancer.

Application(s): BRCA1/2 testing may be considered for individuals with a personal or family history of any of the following: •Early-onset breast cancer (<45 years-of-age) or

bilateral breast cancer•Two primary breast cancers or clustering of breast

and ovarian cancer•Presence of male breast cancer•Ovarian cancer at any age •At-risk populations (e.g. Ashkenazi Jewish descent)

Technique: Sanger + Deletion/Duplication Analysis


TAT: 3-4 weeks

Sample Report: http://www.easternbiotech.com/reports/BRCA1_2.pdf

Mutations in the BRCA1 and BRCA2 genes are the most common causes of hereditary breast and ovarian cancers

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BRCAPlus™ Description: BRCAPlus™ is a next generation sequencing panel

of 6 genes associated with breast cancer (BRCA1, BRCA2, CDH1, PALB2, PTEN, and TP53). These six genes are associated with five hereditary cancer syndromes (hereditary breast and ovarian cancer or HBOC, hereditary diffuse gastric cancer, hereditary breast and pancreatic cancer, Cowden syndrome, and Li-Fraumeni syndrome).

Application(s): •Indications for Testing• Families with a combination of the cancers below and some

common red flags for hereditary cancer in the family would be appropriate to consider for BRCAplus testing:

• Early-onset breast cancer (diagnosed ≤45 years of age)• Male breast cancer at any age• Breast and ovarian cancer in the same woman• Three or more cases of breast cancer*• Three or more cases of breast, uterine, and/or thyroid cancer* *On the same side of the family

•Common Red Flags for Hereditary Cancer• Cancer diagnosed at a younger age than expected for the general

population (≤ 50 years, for most cancers)• Cancer diagnosed across generations, and in multiple generations

within a family, especially if diagnosed younger than average• Individual with multiple primary cancers (either in paired organs or

in different organs)• A pattern of cancer in the family that is typical of a known cancer

predisposition syndrome (e.g.breast and diffuse gastric cancer with CDH1mutations, or breast and thyroid cancer with PTEN mutations)



TAT: 3-4 Weeks

Sample Report: http://www.easternbiotech.com/reports/BRCAplus.pdf

Family with a combination of Breast, Uterine, Thyroid should consider BRCAPlus

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BreastNext™ Description: BreastNext™ is a next generation sequencing (NGS)

panel that simultaneously analyzes 17 genes (ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, MRE11A, MUTYH, NBN, NF1, PALB2, PTEN, RAD50, RAD51C, RAD51D, and TP53) associated with increased risk for breast cancer, including BRCA1 and BRCA2. Mutations in the genes on the BreastNext panel can confer an estimated 20–87% lifetime risk for breast cancer. Some of these genes have also been associated with increased risks for other cancers, such as pancreatic cancer, ovarian cancer, and sarcoma

Application(s): • Indications for TestingFamilies with a combination of the cancers below and some common red flags for hereditary cancer in the family would be appropriate to consider for BreastNext testing.

• Early-onset breast cancer (diagnosed ≤45 years of age)• Male breast cancer at any age• Breast and ovarian cancer in the same woman• Three or more cases of breast cancer*• Three or more cases of breast, ovarian, and/or pancreatic cancer*• Three or more cases of breast, uterine, and/or thyroid cancer**On the same side of the family

•Common Red Flags for Hereditary Cancer• Cancer diagnosed at a younger age than expected for the general

population (≤ 50 years, for most cancers)• Cancer diagnosed across generations, and in multiple generations

within a family, especially if diagnosed younger than average• Individual with multiple primary cancers (either in paired organs or

in different organs)• A pattern of cancer in the family that is typical of a known cancer

predisposition syndrome



TAT: 3-5 Weeks

Sample Report: http://www.easternbiotech.com/reports/BN.pdf

Most comprehensive panel to understand predisposition for Breast Cancer. Also includes Ovarian, Uterine, Thyroid, Pancreatic, Sarcoma etc

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ColoNext™ Description: ColoNext™ is a next generation sequencing (NGS)

panel that simultaneously analyzes 17 genes (APC, BMPR1A, CDH1, CHEK2, EPCAM, GREM1, MLH1, MSH2, MSH6, MUTYH, PMS2, POLD1, POLE, PTEN, SMAD4, STK11, and TP53 ) associated with increased risk for colorectal cancer. Full gene sequencing is performed for 15 of the genes. Gross deletion/duplication analysis is performed for all 17 genes. Specific site Analysis is available for individual gene mutations identified in a family.

Application(s): •Indications for Testing• ColoNext may be appropriate in the following situations, combined

with common red flags for hereditary cancer:• Early-onset colorectal cancer (diagnosed < 50 years of age)• Multiple primary cancers in one person (e.g. two primary colorectal

cancers or colorectal and uterine cancer)• 3 or more family members with colorectal, uterine, ovarian, and/

or stomach cancer• 10 or more GI polyps during one’s lifetime (adenomatous,

hyperplastic, hamartomatous, and/or other types of polyps)• A family history suspicious for several different hereditary

colorectal cancer syndromes• Previous uninformative genetic testing for hereditary colorectal

cancer•Common Red Flags for Hereditary Cancer

• Cancer diagnosed at a younger age than expected for the general population (≤ 50 years, for most cancers)

• Cancer diagnosed across generations, and in multiple generations within a family, especially if diagnosed younger than average

• Individual with multiple primary cancers (either in paired organs or in different organs)

• A pattern of cancer in the family that is typical of a known cancer predisposition syndrome (e.g. colorectal and uterine cancer in Lynch syndrome, or diffuse gastric cancer and lobular breast cancer



TAT: 3-5 Weeks

Sample Report: http://www.easternbiotech.com/reports/CN.pdf

Colorectal cancer (CRC) affects about 1 in 20 (5%) men and women in their lifetime. Find out your predisposition to the cancer!

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GynPlus™ Description: GynPlus is a next generation sequencing panel that

simultaneously analyzes 9 high-risk ovarian and uterine cancer susceptibility genes Genes on this panel include BRCA1, BRCA2, EPCAM, MLH1, MSH2, MSH6, PMS2, PTEN, and TP53. These nine genes are associated with four hereditary cancer syndromes (hereditary breast and ovarian cancer (HBOC), Lynch syndrome, Cowden syndrome, and Li-Fraumeni syndrome, all of which have published management guidelines. Identification of a mutation in one of these genes can help estimate cancer risk and guide treatment, screening, and/or prevention decisions for the patient.

Application(s): •Indications for Testing• Families with a combination of the cancers below and some

common red flags for hereditary cancer in the family would be appropriate to consider for GYNplus .

• Ovarian cancer at any age• Early onset uterine cancer (diagnosed < 50 years of age)• Multiple primary cancers in one person (e.g. uterine and breast or

thyroid cancer)• Multiple close family members with ovarian or uterine and other

cancers (on the same side of the family)• Cancer histories that are suspicious for both HBOC and Lynch

syndrome•Common Red Flags for Hereditary Cancer

• Cancer diagnosed at a younger age than expected for the general population (≤ 50 years, for most cancers)

• Cancer diagnosed across generations, and in multiple generations within a family, especially if diagnosed younger than average

• Individual with multiple primary cancers (either in paired organs or in different organs)

• A pattern of cancer in the family that is typical of a known cancer predisposition syndrome (for example colon and uterine cancer in Lynch syndrome, or breast cancer and sarcoma with a TP53 mutation)



TAT: 3-5 weeks

Sample Report: http://www.easternbiotech.com/reports/GP.pdf

Lifetime risk for hereditary uterine cancer is 60% and ovarian is 40%. Take the test to find your predisposition to gynecological cancers!

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Comprehensive Cancer Panel Description: Comprehensive Cancer Panel is a next generation

full gene sequencing hereditary cancer panel that simultaneously analyzes 122 genes associated with the most common 15 hereditary cancers such as Breast, Ovarian, Colorectal, Endometrial, Melanoma, Pancreatic, Gastric, Prostrate, Thyroid, and many more. About 10% of all cancer cases are due to hereditary cancer. The identification of the genetic cause of cancer in these patients allows the development of a personalized plan for clinical management for the affected patient and family members.

Application(s): •Genetic testing for cancer is recommended for patients with a personal or a family history suggestive of hereditary cancer: Patients with cancer at an early age or with bilateral (more than one primary) cancer or patients with several family members with similar cancer or other manifestations provocative of cancer syndromes.

•The identification of the gene responsible for the observed cancer might influence the treatment of the cancer patient (radiotherapy, surgical or pharmacological management).

•Some mutations are associated with several types of cancer, therefore the identification of the affected gene will result in a preventive plan that involves the different organs that might be affected.

•When the family mutation is known, unaffected individuals can be tested to start risk-reducing interventions before any cancer manifestation.



TAT: 4-6 weeks

Sample Report: http://www.easternbiotech.com/reports/CCP.pdf

An ideal diagnostic tool for patients with non-specific, personal, or family cancer histories.

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5. WELLNESS/ANTI AGING /LIFESTYLE GENETICS TESTSYour Genetics are a Road Map to Health and Wellness. Through the study and use of genetics, we can identify measures

that could lead to the improvement of human health and wellness. These measures and procedures aim to prevent years

of chronic disease and thousands of dollars in health care costs, and provide families and communities with knowledge

of how to live healthier.

Anti-aging medicine is the pinnacle of biotechnology joined with advanced clinical preventive medicine. The specialty is

founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment,

and reversal of age-related dysfunction, disorders, and diseases. The anti-aging medical model aims to both extend

lifespan as well as prolong health span. To support the anti aging medical model, Eastern Biotech & life sciences has added

several specialty profiles that will help individuals manage & improve their health to live productively and independently.

• Geneus™ • Telomere Test• Karmagenes• SkinCareDNA• Fitness & Diet Genetic Test• GPL SNP1000

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Geneus™ Description: Geneus™ is a genetic screening test that analyzes

your DNA for two types of genetic sequence changes: Single Nucleotide Polymorphisms (SNPs), and mutations. Through blood test, Geneus™ screens your DNA for the presence of 2,205 SNPs and mutations with known associations with over 350 medical conditions. The presence of a SNP or mutation in your DNA will not change over the course of your lifetime, making Geneus™ a once in a lifetime screening test.

Application(s): •Your DNA will be screened for Ancestry, Age related conditions, Allergies & Immune conditions, Cancers, Diabetes, Heart related conditions, HLA typing, Infertility & Reproductive health, Intellectual Abilities & Social Behavior, Liver & Kidney conditions, Metabolism & Eating Habits, Ophthalmological disorders, Thrombosis, Blood Clots & Bleeding disorders, & Other condition such as Male Baldness, Sleep Apnea, Restless Legs Syndrome etc.

Technique: NGS


TAT: 4-6 weeks

Sample Report: http://www.easternbiotech.com/reports/Geneus.pdf

Screen your DNA for the presence of 2,205 SNPs and mutations associated with 350+ medical conditions.

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Telomere TestDescription: Telomeres are the ends of chromosomes, which

have an essential role in protecting their integrity in the process of cellular replication.The function of telomeres is to protect chromosome ends from chromosome fusions and degradation, therefore, ensuring the proper functionality and viability of cells. Thus, telomere length serves as the biomarker of the cell replicative capacity, which defines the biological age of the individual. Knowing the biological age is an excellent indicator of individuals’ overall general health status. Secondly, knowing our biological age permits us to obtain a better understanding of the lifestyle habits that impact our aging process. This affords us the opportunity to make appropriate changes and through periodic re-testing measure the results. Thirdly, Life Length’s Telomere Analysis Technology® (TAT®), will allow for more personalized medicine as doctors increasingly treat patients taking into consideration their biological age.

Application(s): Telomere testing is a valuable emerging diagnostic tool within the area of functional and preventive/personalized medicine with a numberof clinical applications including:•An overall global biomarker of health and the

programs and treatments designed to optimize healthy aging

•Early detection of chronic/age-related diseases•Stratifying risk•Prognosis determination•And for tailoring treatments

Technique: Telomere Analysis Technology®

Sample Type: Blood in EDTA

TAT: 6-8 weeks

Sample Report: http://www.easternbiotech.com/reports/TTSR.pdf

Anti Aging starts with the Telomere Test

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Karmagenes TestDescription: How much - Optimist, Spontaneous, Social, Confident,

Innovative, Self-Aware, Risk Taker, Stress Tolerant, Calm, Emotional, Strategic, Bon Vivant, Decisive - are you? Your personality is the result of the long interplay between your DNA, your cultural and social environment ,and the decisions and experiences you get along the road. In other words, a healthy mixture of Nature (DNA and Objectivity) and Nurture (Environment and Perception).Karmagenes offers the first DNA-based personality test. Its top-notch biotechnology links DNA from your saliva sample with 14 behavioral characteristics to define the role of DNA and Environment in shaping our current behavior.

Application(s): •If you want to know what "Be Yourself" finally means? Get Karmagenes genetic test and figure out what is the hidden potential in your DNA.

•The test allows seeing the differences between your genes and your environment, a really valuable tool that can be helpful to better know your personality's strengths and weaknesses, so you can improve where necessary.

Technique: PCR

Sample Type: Buccal (Cheek) Swab

TAT: 3-4 weeks

Sample Report: http://www.easternbiotech.com/reports/KG.pdf

Integrating genetics & psychology for personal development

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SkinCareDNADescription: There are literally thousands of different skin care

products available for consumers today. It is quite an emotionally distressing experience to choose the right product for your skin. Remove any guesswork! Instead use your genetics to get to the Bottom of your skin’s physiology and identify the most suitable skincare product for you.

SkinCareDNA™ a revolutionary DNA test examines 16 genetic markers (SNPs) in the following categories associated with skin aging.•Firmness + Elasticity•Wrinkling (A.G.E.)•Sun Damage + Pigmentation•Free Radical Damage•Sensitivity + Inflammation

Application(s): Results from the test are used to scientifically create a personalized guide that will provide you with a unique regime tailored specifically to you. This test allows you to not depend on ‘one-size-fits-all’ suggestions and enables using the right skincare products based on your skin’s genetic blueprint.

Technique: SNP array


TAT: 3-4 Weeks

Sample Report: http://www.easternbiotech.com/reports/SCD.pdf

Get to the bottom of your skin’s physiology and understand which ingredient is right for your skin!

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Fitness & Diet Genetic TestDescription: Due to our genetic makeup, we are all different in

many ways. There are the physicial differences such as eye and hair color, but then there are the differences inside us such as how we metabolize nutrients, the way we deal with toxins etc. We all interact with the environment in our own unique way. The fitness & diet genetic test helps identify an individual’s genetic predisposition for sporting or fitness profile, idea diet, and personal nutrition needs based entirely on genes.

Application(s): •To better understand their nutrition requirement•To reduce injury rate during workout or athletic

training•To increase fitness performance •To avoid over training in the gym

Technique: PCR


TAT: 3-4 weeks

Sample Report: http://www.easternbiotech.com/reports/FDGT.pdf

Tailor your workout & diet based on what your genes say!

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GPL SNP1000Description: GPL SNP1000 is the most comprehensive test for

alterations in the genetic code in the pathways that are most important for integrative medicine. This test looks at nine core groups of genes which are crucial for many different biological pathways. Previous to GPL-SNP1000, most genetic tests have only looked at a small subset of genes and very few SNPs (single-nucleotide polymorphisms). GPL-SNP1000 includes over 1,000 different SNPs and over 144 different genes. Here are the pathways that GPL-SNP1000 assesses:• DNA Methylation• Oxalate Metabolism• Mental Disorders / SAM-E/B12 Metabolism• Gluten Opioid Peptide Homeostasis• Autism Spectrum Genes• P450s (cyps)• Cholesterol Deficiency• Acetaminophen Toxification/Detoxification• Transporters

Application(s): •GPL-SNP1000 will help you understand how these nine genetic pathways are performing. These pathways have been specifically selected because of their importance in overall health. This test will help you understand your risks for developing different disorders such as ADHD, Adverse Drug Reactions, Allergies, Anxiety, Arthritis, Autism Spectrum Disorders, Bipolar Disorder, Cancer, Depression, Heart Disease, Osteoporosis, Oxidative Stress, Schizophrenia and more

Technique: NGS


TAT: 6-8 weeks

Sample Report: http://www.easternbiotech.com/reports/G-S1000.pdf

9 specific pathways most important for Functional & Integrative medicine!

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6.WELLNESS/ANTI AGING/LIFESTYLE NON GENETIC TESTSAnti-aging medicine is the pinnacle of biotechnology joined with Advanced clinical preventive medicine. The specialty is

founded on application of advanced scientific and medical technologies for the early detection, prevention, treatment,

and reversal of age-related dysfunction, disorders, and diseases. The anti-aging medical model

aims to both extend lifespan as well as prolong health span. To support the anti aging medical model, Eastern Biotech

& life sciences has added several specialty profiles that will help individuals manage & improve their health to live

productively and independently.

• Food Intolerance Test (FOODWatch)

• Food Allergy Test• Executive Wellness Profile• Organic Acid Test• Comprehensive Stool Analysis• Gluten/Casein Peptides Test• Weight Management Profile• Skin Vitality Profile

• Sleep Balance Profile• Adrenal Stress Profile• Fertility Profile• Cardio Metabolic Profile• Neurotransmitters• Urine Hormones Metabolites• Metals Hair Test

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FOODWatchFood Intolerance Test

Description: Food intolerance is an adverse reaction to a particular food, it involves the immune system, and is a less intense reaction. The symptoms can be unpleasant and in some cases severe but are generally not life-threatening. We offer comprehensive panel for food intolerance (200 plus parameters) which are a combination of various groups of foods that help to narrow the specific intolerance to a particular group of foods.

Application(s): Individuals who believe they have an intolerance against a number of foods that create respiratory issues, neural issues, affects their immune system, hair, skin, nails, metabolic problems, musculo skeletal problems, malabsorption problems, gastro-intestinal problems, genital and/or reproductive problems

Technique: Microarray Technology

Test Options:

•Mini 30 Panel (Meat/Dry Fruits/Fruits/Cereals)

•Mini 30 Panel (Vegetarian & Diary)

•Grande 210 Panel (Comprehensive)


TAT: 3-4 business days based on the panel

Sample Report: http://www.easternbiotech.com/reports/FWatch.pdf

Narrow the specific intolerance to a particular group of foods

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Food Allergy Panel Description: Food allergy occurs when the body’s immune system

reacts to a protein in a certain food, causing the release of antibodies and histamine. The release of histamine causes symptoms. Allergy symptoms can begin within minutes to 2 hours of eating the problem food. Symptoms can vary from mild to severe. Even tiny amounts of a problem food can cause serious reactions in very sensitive people. Occasionally, a very severe, rapidly progressing and life-threatening allergic reaction, known as anaphylaxis, can occur. This requires immediate first aid treatment, for example with an EpiPen adrenaline injection. True food allergy is most common in children, but only affects about 1% of adults. Most children will grow out of food allergies by school age, although seafood and nut allergies tend to be life-long.

Application(s): Test can be used when someone has Oral Allergies, Impaired digestion, Leaky Gut,hereditary allergies in the family, Dizziness and Nausea, Vommitting or Diarrhea immediately after eating a food.

Technique: Based on the panel

Test Options:•Food Allergy Panels (20 Allergens & 44 Allergens)

•Respiratory Allergy Panels (20 Allergens & 44 Allergens)


TAT: 1-5 business days based on the panel

Sample Report: http://www.easternbiotech.com/reports/FA.pdf

Allergic reaction to a food can be severe or life-threatening as it usually involves the immune system and affects numerous organs in the body

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Executive Wellness ProfileDescription: In today’s busy lifestyle of excessive work hours and

fast paced environment, and maintaining a work-life balance, we are constantly negotiating the little time we have. We go week after week without paying particular attention to what we eat and find no time for proper exercise. In juggling all these responsibilities, it is hard to monitor one’s health unless we do a regular Health Check. We are aware that such a lifestyle predisposes us to the classic trait of lifestyle diseases such as diabetes, hypertension, heart disease and excess weight. Hence by doing an Executive Wellness check periodically at Eastern, we are confident that you will have the necessary data to be able to keep a check on your health and proactively take any required steps to live a better healthier lifestyle.

Application(s): • Liver Profile (11)• Kidney Profile (5)• Iron Deficiency Profile (3)• Thyroid Profile(3)• Diabetic Screen (2)• CBC (28)• Testosterone

• Cardiac Risk Markers (6)• Ferritin, Arthritis (2)• Electrolytes (2)• Vitamins (3)• Cholesterol Profile (8)• Pancreas (2)

Technique: Several Immunological & biochemical techniques


TAT: 5-7 days+ shipping

Sample Report: http://www.easternbiotech.com/reports/EWP.pdf

A snapshot of your current health & lifestyle!

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Organic Acid Test (OAT) Description: The Organic Acids Test (OAT) provides an accurate

evaluation of intestinal yeast and bacteria. The test includes 74 urinary metabolite markers that can be very useful for discovering underlying causes of chronic illness such as behavior disorders, hyperactivity, movement disorders, fatigue and immune function. The cause of these high levels could include: oral antibiotic use, high sugar diets, immune deficiencies, and genetic factors. The OAT is strongly recommended as the initial screening test. The Microbial Organic Acids Test (MOAT) is ideal for follow-up to the OAT and is often recommended by practitioners looking for a specific abnormality, to monitor certain microbial imbalances, or to assess treatment efficacy.

Application(s): The test can be used to•Evaluate energy production•Assess central nervous system function•Reveal high levels of GI yeast and bacteria•Detect nutritional and antioxidant deficiencies•Determine problems in fatty acid metabolism•Identify excess oxalate

Technique: Gas Chromatography/Mass Spectrometry (GC/MS)

Sample Type: Urine

TAT: 3-4 weeks

Sample Report: http://www.easternbiotech.com/reports/OAT.pdf

Use the metabolic markers in OAT to treat nutrient deficiencies & chronic illnesses

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Comprehensive Stool Analysis Description: Many chronic disorders come from digestive

problems and inadequate nutrient absorption. Proper gastrointestinal function is needed to eliminate toxic substances, pathogenic microbes, and undigested food particles from the body to prevent health problems. Nutrients require a specific internal environment to be properly digested and transported throughout the body. The comprehensive stool digestive analysis (CSDA) detects the presence of pathogenic microorganisms such as yeast, parasites, and bacteria that contribute to chronic illness and neurological dysfunction. It provides helpful information about prescription and natural products effective against specific strains detected in the sample.

Application(s): The test is useful in the diagnosis of intestinal dysfunction without invasive procedures. The test can be used to•Isolate & identify many different pathogens•Assess digestive problems and inadequate nutrient

absorption•Determine any abnormal intestinal microorganisms

in the GI tract•Determine the amount of beneficial bacteria levels

in the GI tract, intestinal immune function, overall intestinal health, and identify inflammation markers

Technique: Multiple immunological techniques

Sample Type: Stool

TAT: 3-4 weeks

Sample Report: http://www.easternbiotech.com/reports/CSA.pdf

CSDA is an overall assessment of the patient’s digestive system

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Gluten/Casein Peptides Test Description: The Gluten/Casein Peptides Test can determine

the inability to digest wheat, rye, barley, and milk. These undigested proteins, called peptides, are associated with gastrointestinal, neurological, and neuro-Developmental disorders. The Gluten/Casein Peptides Test determines sensitivities, even when a patient has no IgE or IgG allergic reactions to these foods. If either of the peptide results is abnormal, both gluten (from gliadorphin) and casein (from casomorphin) should be eliminated.

Application(s): This test is a very useful tool in determining whether dietary modifications should be part of an integrated treatment plan, or whether the diet should be maintained. It is recommended for the following disorders:

Technique: Elisa

Sample Type: Urine

TAT: 3-4 weeks

Sample Report: http://www.easternbiotech.com/reports/GCP.pdf

Assess the elevated amounts of peptides (Gluten & Casein) that can cause an opiate-like effect

• AD(H)D • AIDS • Alzheimer’s Disease • Arthritis • Autism Spectrum Disorders • Chronic Fatigue Syndrome • Colitis & Crohn’s Disease • Depression • Diarrhea/Constipation

• Down Syndrome • Fibromyalgia • Behavioral Disorders • Multiple Sclerosis • OCD • Psychoses • Schizophrenia • Tic Disorder • Tourette Syndrome

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Weight Management Profile Description: The Weight Management Profile can detect key

hormone imbalances that undermine patients' best efforts to control their weight. It identifies hormonal imbalances that contribute to obesity, weight gain, difficulty losing or sustaining a healthy weight, slowed metabolism, increased body fat deposition, and food/sugar cravings. Used as a screening tool, it serves as an early indicator, of insulin resistance and risks for metabolic syndrome and diabetes.

Application(s): •Test can be used for Women with premenstrual weight gain and fluid retention; perimenopausal and/ or menopausal weight gain in hips/thigh, and/or inability to lose/tendency to regain weight, central obesity, PCOS, adrenal and thyroid dysfunction; breast cancer risks.

•Test can be used for MEN with andropausal weight gain in hips/thighs and/or inability to lose/tendency to regain weight, central obesity, adrenal and thyroid dysfunction; prostate cancer risks. • Optional Thyroid Add-on: free T3, free T4, and TPOab antibodies

provide a better estimation of thyroid hormone bioavailability to facilitate effective thyroid therapy. Consider when symptoms of thyroid deficiency are problematic.

• Optional Cardio Add-on: Cardiometabolic risk markers hs-CRP, triglycerides, total cholesterol, LDL, HDL and VLDL cholesterol for early detection of pro-inflammatory CVD risks and prediabetes.

•Consider test for abdominal obesity, and symptoms of insulin resistance/metabolic syndrome

Technique: Multiple Immunological Techniques

Sample Type: Saliva & Blood Spot


Sample Report: http://www.easternbiotech.com/reports/WMP.pdf

Can’t lose weight? Identify the hormonal imbalances causing your weight gain!

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Skin Vitality Profile Description: Skin is not only a major target of hormone action, it

is also a site of local hormone synthesis, activation and metabolism. The range of hormones tested in the Skin Vitality Profile can help providers identify hormone deficiencies or excesses that are contributing to skin problems.

Application(s): •Consider test for patients with thinning skin, wrinkling, dryness, oiliness, acne, hirsutism, hair loss, melasma, itching, myxedema, or slow wound healing.

Technique: Multiple immunological techniques



Sample Report: http://www.easternbiotech.com/reports/SVP.pdf

Discover the hormonal connection that is vital to youthful skin.

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Sleep Balance Profile Description: When the master stress hormone cortisol is

chronically elevated, particularly at night, it inhibits sleep and leads to lower melatonin levels. In addition to stress-related sleep disturbances, melatonin levels naturally dine as we age – triggering further imbalances. The Sleep Balance Profile – the first four-point test offers a complete diurnal pattern of melatonin and cortisol to help patients struggling with hormone-related sleep imbalances.

Application(s): •The Sleep Balance profile allows patients to find the source of troublesome sleep problems offering long-term treatment solutions.

•The test can be used for patients with inability to get to sleep, chronic sleeplessness affecting vitality, frequent waking, cognition, weight, diabetes, and cardiovascular risks.

•The test allows physicians to pin point imbalance of melatonin and cortisol circadian rhythms associated with acute or chronic sleep disturbances.

Technique:Liquid Chromatography/Tandem Mass Spectrometry

(LC-MS/MS)

Sample Type: Dried Urine


Sample Report: http://www.easternbiotech.com/reports/SBP.pdf

Uncover hidden barriers to a restful sleep

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Adrenal Stress Profile Description: The Adrenal Stress profile measures the DHEA

and diurnal Cortisols, and is the accepted industry standard for evaluating adrenal health. Samples collected at four critical time points in one day provide a useful picture of adrenal function to help patients dealing with stress-related symptoms and disorders. The difference between stress we can handle and stress that gets out of hand is the difference between adrenal balance or imbalance. Both high and lows of the key adrenal hormones, DHEA and Cortisol, can play havoc with body systems and related hormones – triggering further imbalances.

Application(s): •The profile is used to determine if your adrenal functions are burnt out and if you are suffering from adrenal fatigue.

•It allows you to find the source of adrenal imbalances underlying patient symptoms, offering long-term treatment solutions.

Technique: Enzyme Immunoassay (EIA)

Sample Type: Saliva


Sample Report: http://www.easternbiotech.com/reports/ASP.pdf

Find out if stress hormones are out of balance to effectively manage your stress.

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Fertility Profile Description: The profile provides a thorough evaluation that

can identify many problems related to hormone imbalances that affect fertility. Early detection can help your patients address those issues and identify the need for more specialized care. Patients can collect their samples conveniently and at the appropriate cycle times with minimal disruption to their lives and busy work schedules. Sampling is done on days 3 and 21 of the menstrual cycle. Dried blood spot samples are collected on days 3 and 21 of the menstrual cycle, and saliva samples are collected only on day 21. The day 3 sample is optimal for assessment of ovarian reserves with the FSH and LH tests, while the other hormones are measured mid-luteally (day 21 commonly), when the level of hormones should be optimal for a successful pregnancy.

Application(s): The Fertility Profile is geared towards women •who have irregular cycles or fertility issues•who have been trying to get pregnant without

success, or •who would like to be proactive in their preconception

planning by getting a baseline screening

Technique: Enzyme Immunoassay (EIA)



Sample Report: http://www.easternbiotech.com/reports/FP.pdf

Feel as if the clock is ticking in you and unable to conceive? Fertility profile can uncover underlying hormonal imbalances.

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Cardio Metabolic ProfileDescription: Risk for Cardio Vascular Disease and Diabetes II

is known to be particularly high in people who have a disorder known as “metabolic syndrome”, which is often associated with being overweight. CardioMetabolic Profile tests blood markers that can identify people at high risk of these diseases. If levels of several of these blood markers are abnormal, this should be an important “wake-up call” to tackle the problem. Biomarkers such as In, hsCRP, HbA1c, TG, CH, HDL, LDL, VLDL) are used to asses risk factors for the metabolic syndromes.

Application(s): Test is used to Identify individuals at risk for CardioMetabolic/Insulin resistance syndromes. It is very likely that one can be diagnosed with metabolic syndrome if any of the following conditions are present:•Obesity, especially in the waist/abdominal area (the

“apple-shaped” body type)•A body mass index (BMI) greater than 25•High blood pressure•Insulin resistance and/or glucose intolerance (high

fasting blood glucose or high fasting insulin levels)•An abnormal lipid profile known as “atherogenic

dyslipidemia” (low HDL cholesterol, high LDL cholesterol, high VLDL cholesterol, high triglycerides)

•InflammationInsulin resistance, atherogenic dyslipidemia, and inflammation are known as cardiometabolic risk factors and can only be assessed by a blood test such as the CardioMetabolic Profile.

Technique: Multiple Immunological techniques

Sample Type: Dried Blood Spot


Sample Report: http://www.easternbiotech.com/reports/CMP.pdf

Simple lifestyle changes may improve overall risk for Cardio Vascular Disease and Diabetes II. Identify the risks from a simple blood spot test

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NeurotransmittersDescription: Testing neurotransmitters in patients with

psychological conditions can help target specific imbalances – getting to the root of persistent issues such as adrenal dysfunction, mood disorders, lack of ambition and lack of appetite. Neurotransmitter testing gives practitioners a diagnostic edge over the traditional psychological inventory. It offers the advantage of zeroing in on which therapies are best suited for an individual patient. Combining neurotransmitter testing with other hormone testing gives practitioners an even deeper insight into a patient’s Individual neurochemistry.

Application(s): Patients who should be tested include those who suffer from:•Insomnia•Depression•Persistent fatigue•Poor memory•Anxiety•Low libido•Feeling perpetually drained

Technique: Multiple Immunological techniques



Sample Report: http://www.easternbiotech.com/reports/NTM.pdf

Suffering from psychological symptoms? Imbalances in neurotransmitters can cause the brain & body to be over- or under- stimulated that can lead to such symptoms!

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Urine Hormones MetabolitesDescription: Test assesses both parent hormones and their

corresponding metabolites, it reveals how the body is breaking down key hormones like estrogens, progestogens, androgens, cortisol and melatonin. This testing gives insight into whether we are fully detoxifying our hormones, which is important because some hormones can be carcinogenic if they don’t break down properly – leaving us more at risk for a variety of diseases, like cancer.

Application(s): It a good idea to consider urinary hormone testing for •At risk of hormone-dependent cancers – like breast

cancer or prostate cancer•Showing normal saliva cortisol levels but still

experiencing symptoms of adrenal dysfunction•Considering hormone replacement therapy•Experiencing symptoms of cortisol imbalance•Having symptoms of hormonal imbalance such as

weight gain and insomnia

Technique: Chromatography/Mass Spectrometry



Sample Report: http://www.easternbiotech.com/reports/UHM.pdf

There are steps you can take if you are concerned about how your body is processing hormones!

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Metals Hair TestDescription: Heavy metals toxicity caused by increasing levels of

pollution and use of chemicals in industry is a growing threat to our health and development of our children. High levels of toxic metals deposited in body tissues and subsequently in the brain, may cause significant developmental and neurological damage. A Metals Hair Test is ideal for checking current exposure to toxic metals. Hair provides important information that can assist the practitioner with an early diagnosis of physiological disorders associated with aberrations in essential and toxic element metabolism.

Application(s): Hair element analysis provides important information which, in conjunction with symptoms and other laboratory values, can assist the physician with an early diagnosis of physiological disorders associated with aberrations in essential and toxic element metabolism.•Determine if metal toxicity or mineral deficiency is

contributing to the disorder•Monitor the effects of chelation (elimination of

heavy metals from the body)•Identify if supplementation of important minerals

may bring about significant improvements

Technique: Mass Spectrometry (ICP/MS)

Sample Type: Hair

TAT: 2-3 weeks

Sample Report: http://www.easternbiotech.com/reports/MHT.pdf

Toxic metals can affect development, neurological functioning, and overall health

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7.COUNSELING SERVICESCounseling is a collaborative process that involves the development of a confidential

professional relationship that focuses on personal problems. It is an opportunity to

talk to a licensed personnel who is a skilled listener trained in the appropriate field.

The objective of counseling is to help you clarify issues, gain insight into your feelings

and thoughts and deal with the problems effectively. The most helpful aspect of

counseling is that the counselor is objective and is not involved in the situation you’re

trying to resolve. The counselor has only your best interests to consider.

• Genetic Counseling• Nutritional Consultation

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Genetic tests are incomplete without appropriate advice and guidance. Genetic counselors need to frequently speak

to the clients about complex scientific and emotional issues.

The counseling involves – •Confirming, diagnosing or ruling out a genetic condition.•Management. •Communicating genetic risk for future generation. •Providing psychological support.

Our highly qualified genetic counselors offer pre and post test counseling either online, by telephone, or in person.

www.geneticcounseling.ae

Genetic Counseling

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Nutritional consultation involves building a detailed picture of lifestyle, eating habits, medical history and any

concerns one may have about their health. Our nutritional consultant can work to form an eating plan that suits

client’s needs, their lifestyle and daily commitments. The consultant will help clients identify and avoid unnecessary

or harmful foods and enjoy an abundance of wonderful food that makes him feel good in body and in mind. The clients

will take away a tailor-made plan of action knowing exactly what they need to do next.

www.nutritionhelp.info

Nutritional Consultation

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PREDICTIVE - PREVENTIVE - PERSONALISED …...innovative technologies and exceptional customer...

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