Ppt Case Misun

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    Department of Pediatric

    Dr. Mohammad Hoesin General Hospital

    Sriwijaya University Faculty of Medicine

    2!"

    Case Presentation

    Presented by:

    Mentari Indah Sari

    Erniyanti Puspita Sari

    Advisor:Dr. Achirul Bakri, SpA!"

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    I. INTRODUCTION

    #

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    # Diarrhoea remains one of the major causes of mor$idityand mortality of children in developin% countries .

    # Most of acute diarrhea caused $y infection. Many of theimpacts that occur due to infection of the %astrointestinaltract includin% to&in that can cause impaired secretion andrea$sorption of 'uid and electrolyte due to dehydration(electrolyte $alance disorders and acid#$ase $alancedisorder. )he invasion and destruction of epithelial cells (

    penetrate into the lamina propria and dama%e the microvillimay constitute a maldi%est and mala$sorption .

    # )o carry out the treatment of diarrhea in a comprehensive (e*cient and e+ective way( it must $e done rationally. )heuse of oral rehydration solutions are %enerally e+ective in

    correctin% dehydration. ,ntravenous 'uid administration isneeded if there is a failure $ecause of the hi%h fre-uency ofdiarrhea( uncontrolla$le vomitin% and oral input todisruption due to infection. Some ways of prevention $yvaccination and the use of pro$iotics has $een widelydisclosed and treatment with specic anti$iotics and

    antiparasitic.

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    II. PATIENT STATUS

    $

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    ,D/0),F,1),30

    0ame 4 0%e 5 6irth date 4 !! months5 March( !7th2!7Se& 4 Female8ei%ht 4 9 :%Hei%ht 4 "; cmenten ?aut )l.

    >elapa

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    0M0/S,S

    Blloanamnesis4 patientCs mother( !! March 2!7(!".

    1hief 1omplain 4 8atery stoolSecondary 1omplain 4 Eomit and fever

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    History

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    )here was no previous illness with similar symptoms)here was no aler%ic history of mil:( food( and dru%s

    History in familial illness with the same complaintin the family denied

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    Pre%nant duration 4 term

    Parturition 4 SpontaneousHelped $y 4 MidwifeDate 4 March( !7th2!"6irth wei%ht 4 2A %ram6irth len%th 4 A cm6irth condition 4 spontaneous cryin%

    BirthHistor

    y

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    Feeding History6reast mil: 4 #" months

    Formula mil: 4 " months# present

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    ?yin% down on stomach 4 @ monthsSittin% 4 " monthsStandin% 4 ! months8al:in% 4!! months

    )al:in% Bmama papa 4 ; months

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    1onclusion4 6asic immuni=ation complete

    ,mmuni=ation

    B#si$ I""%nition

    ! 6ln @ $ln ; $ln

    BCG J

    DPT ( J DP) 2 J DP) @ J

    HEPATITIS B(

    J H/P),),S62

    J H/P),),S6@

    J

    Hi) ( J Hi$ 2 J Hi$ @ J

    PO*IO ( J P3?,3 2 J P3?,3 @ J

    +e#ses J

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    Physical /&aminationB!! March 2!"

    General condition4 mild illness 1onsciousness 4 1ompos Mentis

    /dema B# 5#( sianosis B#5#(dyspnue B#5#( anemia

    B#5#( icteric B# 5#(dismorc B#5#

    )emp 4 @9 31

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    8ei%ht 4 9 >%?en%th 4 "; cm

    8ei%ht5%e 4 SD #2 SD?en%th5%e 4 SD #2 SD8ei%ht5?en%th 4 #! SD #2 SD

    1onclusion 4 0ormowei%ht

    N%trition St#te

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    Specic /&amination

    Shape 4 0ormocephaly( symmetrical(dysmorphic B#

    Hair 4 6lac:( strai%ht( not easilypulled o+

    /yes 4 Sun:en eyes B5( tears B(pupils4 round( isocoric( L @mm(li%ht re'e&es 5( paleconjunctiva B#( icteric sclera B#0ose 4 Secretion B#( nasal 'arin% B#./ars 4 Secretion B#.

    Mouth 4 Dry oral mucosa and lipsB(cyanosis B#

    )hroat 4 Hyperemic pharyn& B#( )onsil)!#)!Ne$, 4 ?ymph node enlar%ement B#

    He#d

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    , 4 Static5dynamic4 symmetrical( retraction#5#P 4 Stem fremitus left ri%htP 4 Sonorous in $oth hemithora& 4 0ormal vesicular sound( rhonchi B#(whee=in% B#.

    P%"o

    , 4 ,ctus cordis not visi$le

    P 4 0o palpa$le thrillP 4 0ormal heart line 4 H< !!A $pm( re%ular rhythm( heartsound ,#,, normal( additional sounds B#

    He#rt

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    , 4 Stomach raised 4 ,ncreased $owel sound BA &5minP 4 Supple( liver and spleen not palpa$le(s:in tur%or decreased BN2O( tenderness B#P 4 )ympanic( shiftin% dullness B#

    A)do"en

    ,n%uinal 4 ?ar%e lymphnode B#(eritema perianal B#( prolaps ani B#

    /&tremity 4 cold acral B#( cyanosis B#( edema

    B#

    Genitalia 4 0ormal.

    0eurolo%ic e&amination is normal

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    cute diarrhoea e.c susp. Eiral infection with mild moderatedehydration Failure of oral rehydration

    cute diarrhoea e.c susp. 6acterial infection with mild moderatedehydration Failure of oral rehydration

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    cute diarrhoea e.c susp.

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    )herapy

    dditional /&amination?a$oratory of 6lood analysis and electrolit

    ?a$oratory of Faeces analysis

    )herapy B Supportive Simptomatic#1ausative0on Pharmacolo%ist

    ,nform patientCs condition

    /ducate oralit usa%e

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    )herapy

    Pharmacolo%ist% ,EFD

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    Pro%nosis

    6onam

    6onam

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    FO**O-UP

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    & 6lood analysis B /mer%ency Unit !!#@#2!" on !74"

    & H$ 4 !!(A %5dl B!!(!#!( %5dl

    & Ht 4 @7 volR B@7#! volR

    & /ritrosit 4 ("" &! mm@5jam B@(9!#(27 &! mm@5jam

    & ?eu:osit 4 ;.A5mm@ B".#!9.7 5mm@

    & )rom$osit 4 2;.5mm@ B2!9.#;9.5mm@

    & Hitun% jenis 4 5!5@;5A5!2 B#!5!#"57#952#52#Amm@

    & ?/D 4 !"mm5jam BN2 mm5jam

    Tanggal Keterangan !@#@# S >eluhan 4 66 cair B 2&( darah B#(

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    !2#@#2!"

    S >eluhan 4 66 cair B @&( cair ampas( darah B#( lendir B#( muntah Btiap ha$is ma:an( isi apa yan%dima:an $anya:nya T %elas$elim$in%( demam B#.O Sense 4 1M; 0 4 !A&5menit ulit 4 tur%or normal

    >epala 4 UU6 ce:un% B#( matace:un% B#( air mata 5( mu:osa$i$ir :erin% B#

    )hora:s 4 simetris( retra:si B#Pulmo 4 vesi:uler B normal(ron:hi B#(

    whee=in% B#1or 4 H< !A&5menit( 6 ,dan ,,

    normal( murmur B#(%allop B#$domen $domen 4 datar(lemas( 6U B menin%:at( hepar5lientida: tera$a( cu$itan :ulit perut:em$ali cepat/:stremitas 4 a:ral din%intida: ada( 1onsistensi4 ?em$e:moe$a4 ne%atif/ritrosit4 0e%atif?eu:osit4 !#25lp6a:teri4 ne%atif

    amur4 0e%atif)elur cacin%4 ne%atifSisa ma:anan B:ar$ohidrat( protein(

    lema:4 ne%atifDarah samar4 ne%atif

    @ @2!"

    e u a ca B ( da a B (lendir B#( muntah B#O Sense 4 1M0 4 ;A&5menit

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    14-3-2016 S >eluhan 4 66 cair B# dan muntah B#O Sense 4 1M; 0 4 ;A&5menit

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    III. *ITERATURE RE0IE-

    #'

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    Diarrhea

    & Diarrhea4 defecation withli-uid5semisolid feces Bmore watercontent for 2 %rams or 2

    ml52h& 8H3 denition4 watery defecation

    @&5d( with or without mucus or $lood

    in feces& A$%te di#rrhe# less than a wee:( N

    episodes5month

    #(

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    /pidemiolo%y

    & Mostly in the rst 2 years of life

    & Hi%hest incidence4 #ge 1/(( "onths

    ) Decline in maternal anti$ody and childCs

    low active immunity) ,ntroduction of food possi$ly

    contaminated

    ) Direct contact with fecal materialBanimal5human when child startscrawlin%

    #*

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    Asy"!to"#ti$ In2e$tion

    & Proportion increases after the a%e of 2

    formation of active immunity& Durin% this phase( fecal material contains

    infectious patho%ens Bviral( $acteria( proto=oalcysts

    &

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    /tiolo%y

    & ,nfectious diarrhea types4 non-infammatory andinfammatory) 0on#in'ammatory4 $acterial enteroto&in production(

    villi surface destruction $y viral( attachment $yparasites( attachment and5or translocation of$acteria

    ) ,n'ammatory4 direct $acterial invasion( cytoto&inproduction

    & 0on#infectious diarrhea4) Food aller%ies) 0eoplasms

    ) natomical defects Bmicrovilli atrophy( malrotation(Hirschsprun%

    ) Mala$sorptions) Food poisonin%) ,mmune deciency

    +#

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    1ommon /tiolo%y

    ++

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    Spread of ,nfection

    & Fecal#oral 4 3 F 4 fnger, ies, uid,feld

    ) Food5water contamination $y

    enteropatho%ens) Hand contact with patient5contaminated

    $elon%in%s

    ) ,ndirectly4 throu%h 'ies

    +$

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    Pathophysiolo%y

    & 3smotic diarrhea4) Material not a$sor$ed BM%( %lucose( sucrose(

    lactose( maltose in colon di+erent osmolarity$etween intestinal lumen and $lood water

    'ows into lumen

    water collection

    e&ceedscolonCs a$sorption capacity diarrhea

    & Secretory diarrhea4) Stimulation $y enteroto&in 0a a$sorption $y

    villi disrupted 1l secretion increases water

    and electrolyte are passed out as watery stool& Motility distur$ances& ,n'ammation of the colon and small

    intestine

    +

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    1linical Manifestations

    & G, symptoms4 diarrhea( a$dominal cramps(vomitin%

    & /lectrolyte and water loss4 dehydration(meta$olic acidosis( hypo:alemia

    &

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    Rotaviral Shigella Salmonella ETEC EIEC Cholera

    Incubation

    Fever

    Nausea/vomitingAbdominal pain

    Headache

    Duration

    17-72 hrs

    +

    OftenTenesmus

    -

    5-7 days

    24-48 hrs

    ++

    SeldomTenesmus

    !ram"

    +

    #7 days

    6-72 hrs

    ++

    OftenTenesmus !ol$!

    +

    3-7 days

    6-72 hrs

    -

    +-

    -

    2-3 days

    6-72 hrs

    ++

    -Tenesmus

    !ram"

    -

    %ar$es

    48-72 hrs

    -

    Often&ram"

    -

    3 days

    Feces

    !olume

    Fre"uenc#

    Consistenc#

    $lood

    SmellColor

    %$C

    &thers

    'ed$um

    5-10()d

    *atery

    -

    otten,ello-

    green$sh

    -

    .nore($a

    /e

    #10()d

    *atery

    +

    -ed-

    green$sh

    +

    &onuls$on

    +

    /e

    Often

    Sem$sol$d

    Somet$mes

    /oulreen$sh

    +

    Se"s$s +

    . lot

    Often

    *atery

    -

    -o !hange

    -

    'eteor$smus

    /e

    Often

    Sem$sol$d

    +

    -ed-

    green$sh

    -

    System$!

    $nfe!t$on +

    . lot

    &ont$nuous

    *atery

    -

    /$shy$!e ater

    -

    -

    +'

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    Dia%nosis

    & namnesis4) Duration( volume of feces

    ) Fecal consistency( color( smell( presence5a$senceof mucus and $lood

    ),f vomitin% is present4 volume and fre-uency) Urination BnormalV DecreasedV Has not passedurine in "#A hoursV

    ) Food and drin:s %iven durin% diarrhea

    ) Fever( other accompanyin% diseases Bcou%h( runny

    nose( otitis media( measles) Medication( oralit administration( administered

    dru%s

    ) ,mmuni=ation history

    +(

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    & Physical /&amination) 6ody wei%ht( vital si%ns

    ) Si%ns of dehydration

    ) >ussmaul respiration4 meta$olic acidosis

    ) 8ea: or a$sent $owel sounds4hypo:alemia

    ) /&tremity4 1

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    MM8< Dehydration1lassication

    $

    8H3 D h d i

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    8H3 Dehydration1lassication

    $-

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    ?a$oratory ,nvesti%ations

    & 1omplete la$ wor:up %enerally not re-uiredunless un:nown underlyin% cause or otherconditions Bsepsis( severe dehydration

    & Sometimes needed4

    & 6lood4 1omplete $lood count( serumelectrolyte( $lood %ases analysis( %lucose(culture( resistance test

    & Urine4 urinalysis( culture( resistance test

    & Feces4 macroscopic Bconsistency( color(presence of $lood5mucus( smell( froth andmicroscopic Bleu:ocyte( stainin%

    $#

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    Mana%ement

    & Principles BWpillarsO4 rehydration(nutritional support( medication asindicated( parent education

    & )reatment plans4 accordin% to 8H3dehydration classication) Plan 4 no dehydration

    ) Plan 64 some dehydration

    ) Plan 14 severe dehydration

    $+

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    $$

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    $

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    $/

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    5in$ S%!!e"ent#tion

    & 8H35U0,1/F4

    ) X" months old4 ! m%5day for !#! days) " months old4 2 m%5day for !#! days

    Feeding

    & 1hildren with diarrhea must still $e fed) 6reastfed $a$ies4 as often as possi$leY on

    demand

    ) 6a$ies( not $reastfed4 mil: at least every @hours

    ) 1hildren Z months old with soft5solid foods4continue feedin% in small $ut fre-uent servin%sB"&5more

    $'

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    Medications

    & nti$iotics4 %enerally not re-uired in acutediarrhea Bmost are due to

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    Medications

    & ntidiarrhea4 often used $ut has nopractical $enet not indicated totreat acute diarrhea in children

    & Pro$iotics and Pre$iotics promotes$alance of intestinal micro'ora

    $*

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    1omplications

    & /lectrolyte ,m$alances4) Hypernatremia

    ) Hyponatremia

    ) Hypo:alemia& Fever& /dema53verhydration

    & Meta$olic cidosis& Paralytic ,leus

    & 1onvulsions

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    Prevention

    & Proper $reastfeedin%& Proper preparations and stora%e of food

    & Use of su*cient clean water

    & Ma:es ha$it of handwashin% with soap afterdefecation and $efore eatin%

    & Use of hy%ienic and clean lavatory $y all familymem$ers

    & Proper stool disposal

    & Host immunity#related4

    ) 6reastfeedin% until a%e 2) ,ncreasin% nutritional value of foods and ade-uate

    feedin% improves nutritional status

    ) ,mmuni=ation Bmor$illi( rotaviral

    -

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    Pro%nosis

    & +ost 6789: resove in ;< d#ys

    & few B7R continue $ut resolve inN! days

    & 7R $ecome persistent diarrhea

    #

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    I0. CASE ANA*=SIS

    +

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    namnesis

    & 8atery stooldefecation !&5daywithout $lood ormucus and volume4 T cup each

    defecation and lastfor N! days B! day& Mild fever& 3ften vomittin% &

    T cup each vomit

    $

    &Acute diarrhea

    &0iral In1ection

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    Physical /&amination

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    /

    Rotaviral Shigella Salmonella ETEC EIEC Cholera

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    Incubation

    Fever

    Nausea/vomiting

    Abdominal pain

    Headache

    Duration

    17-72 hrs

    +

    Often

    Tenesmus

    -

    5-7 days

    24-48 hrs

    ++

    Seldom

    Tenesmus!ram"

    +

    #7 days

    6-72 hrs

    ++

    Often

    Tenesmus !ol$!

    +

    3-7 days

    6-72 hrs

    -

    +

    -

    -

    2-3 days

    6-72 hrs

    ++

    -

    Tenesmus!ram"

    -

    %ar$es

    48-72 hrs

    -

    Often

    &ram"

    -

    3 days

    Feces

    !olume

    Fre"uenc#

    Consistenc#

    $lood

    Smell

    Color

    %$C

    &thers

    'ed$um

    5-10()d

    *atery

    -

    otten

    ,ello-

    green$sh

    -

    .nore($a

    /e

    #10()d

    *atery

    +

    -

    ed-

    green$sh

    +

    &onuls$on

    +

    /e

    Often

    Sem$sol$d

    Somet$mes

    /oul

    reen$sh

    +

    Se"s$s +

    . lot

    Often

    *atery

    -

    -

    o !hange

    -

    'eteor$smus

    /e

    Often

    Sem$sol$d

    +

    -

    ed-

    green$sh

    -

    System$!

    $nfe!t$on +

    . lot

    &ont$nuous

    *atery

    -

    /$shy

    $!e ater

    -

    -

    '

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    Mana%ement

    &

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    Pro%nosis

    Kuo ad vitam et functionam4 d%)i# #d)on#"

    & Eiral infection e.%

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    )han:

    you

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