Poultry Nutritional Supplement · Ration PlusTM supplemented through feed pelleted at 76.6°C...

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D. D. Hall 1 , E. Wozniak 1 , and M. D. Sims 2 . 1 Cytozyme Laboratories, Inc., South Salt Lake City, UT, USA,. 2 Virginia Diversified Research Corp, Harrisonburg, VA, USA. A 21-day trial was conducted with liquid and dry Ration Plus TM for Poultry (RP; AAFCO 36.11 Lactobacillus acidophilus fermentation product). RP was applied to antibiotic-free corn-soy based diets pre-pelleting with dry RP at 0, 0.05 or 0.10%, and post-pelleting with liquid RP at 0.05% in a soy- oil carrier. Pelleting was performed at 76.6 o C (170 o F). Straight-run Cobb 500 broiler (n= 768) chicks were randomly assigned to 32 pens of 24 chicks (8 replications/treatment). A live coccidia vaccine was administered at the hatchery. On day four, chicks were exposed to used litter from a healthy flock. Heat stress at bird-level was maintained at 35 o C (95 o F) on days 0-7, 38 o C (100 o F) on days 7-14, and 40 o C (105 o F) on days 14-21. Results showed that body weights were not affected by the supplement. Final results further demonstrated that the mortality adjusted feed conversion in the control group (1.46) was significantly (P<0.05) higher than in the 0.05% liquid RP group (1.30) and in both 0.05% and 0.10% dry RP groups (1.36 and 1.34, respectively). The three RP treatments, post-pelleted liquid, and pre-pelleted 0.05% and 0.10% dry, had significantly (P<0.05) lower mortality (13.1, 18.8 and 15.6%, respectively) than that of the control (30.7%). RP improved mortality adjusted feed efficiency and lowered mortality in broilers. Comparison of RP results pre- and post-pelleting indicated that RP was pellet stable under the reported trial conditions. These data suggest that RP dry formulation may be effective in minimizing broiler mortality caused by heat stress during the extremes of hot summer weather conditions. Key Words: antibiotic-free, broiler, heat stress, pellet Ration Plus TM supplemented through feed pelleted at 76.6°C (170°F) improved performance of Straight Run Cobb 500 broilers during 21 day evaluation under heat stress conditions. Poultry | Nutritional Supplement Effects of Ration Plus TM on Broiler Chickens Fed Antibiotic-Free Diets Added Pre- or Post-Pelleting in Heat Stress Environments. Pelleting Effects Ration Plus TM applied in pelleted diets improved performance of broilers Data presented at International Scientific Poultry Forum (IPSF) 2017 Atlanta Georgia, USA, Booth C72 0.572 a Body Weight (kg) 0.567 a 0.552 a 0.573 a 30.7 a Mortality (%) 18.8 b 15.6 b 13.1 b 1.46 a Mortality-adjusted Feed Conversion Ratio 1.36 ab 1.34 b 1.30 b Control Performance Parameter 0.05% Dry (Pre-pelleted) 0.10% Dry (Pre-pelleted) Ration Plus Application Dose (Method) 0.05% Liquid (Post-pelleted) Means with different letters in a row indicate significant difference (P≤0.10 by LSD test).

Transcript of Poultry Nutritional Supplement · Ration PlusTM supplemented through feed pelleted at 76.6°C...

Page 1: Poultry Nutritional Supplement · Ration PlusTM supplemented through feed pelleted at 76.6°C (170°F) improved performance of Straight Run Cobb 500 broilers during 21 day evaluation

D. D. Hall1, E. Wozniak1, and M. D. Sims2. 1Cytozyme Laboratories, Inc., South Salt Lake City, UT, USA,. 2Virginia Diversified Research Corp, Harrisonburg, VA, USA.

A 21-day trial was conducted with liquid and dry Ration PlusTM for Poultry (RP; AAFCO 36.11 Lactobacillus acidophilus fermentation product). RP was applied to antibiotic-free corn-soy based diets pre-pelleting with dry RP at 0, 0.05 or 0.10%, and post-pelleting with liquid RP at 0.05% in a soy-oil carrier. Pelleting was performed at 76.6oC (170oF). Straight-run Cobb 500 broiler (n= 768) chicks were randomly assigned to 32 pens of 24 chicks (8 replications/treatment). A live coccidia vaccine was administered at the hatchery. On day four, chicks were exposed to used litter from a healthy flock. Heat stress at bird-level was maintained at 35oC (95oF) on days 0-7, 38oC (100oF) on days 7-14, and 40oC (105oF) on days 14-21. Results showed that body weights were not affected by the supplement. Final results further demonstrated that the mortality adjusted feed conversion in the control group (1.46) was significantly (P<0.05) higher than in the 0.05% liquid RP group (1.30) and in both 0.05% and 0.10% dry RP groups (1.36 and 1.34, respectively). The three RP treatments, post-pelleted liquid, and pre-pelleted 0.05% and 0.10% dry, had significantly (P<0.05) lower mortality (13.1, 18.8 and 15.6%, respectively) than that of the control (30.7%). RP improved mortality adjusted feed efficiency and lowered mortality in broilers. Comparison of RP results pre- and post-pelleting indicated that RP was pellet stable under the reported trial conditions. These data suggest that RP dry formulation may be effective in minimizing broiler mortality caused by heat stress during the extremes of hot summer weather conditions.

Key Words: antibiotic-free, broiler, heat stress, pellet

Ration PlusTM supplemented through feed pelleted at 76.6°C (170°F) improved performance of Straight Run Cobb 500 broilers during 21 day evaluation under heat stress conditions.

Poultry | Nutritional Supplement

Effects of Ration PlusTM on Broiler Chickens Fed Antibiotic-Free Diets Added Pre- or Post-Pelleting in

Heat Stress Environments.

Pelleting EffectsRation PlusTM applied in pelleted diets improved performance of broilers

Data presented at International Scientific Poultry Forum (IPSF) 2017Atlanta Georgia, USA, Booth C72

0.572aBody Weight (kg) 0.567a 0.552a 0.573a

30.7aMortality (%) 18.8b 15.6b 13.1b

1.46aMortality-adjusted Feed Conversion Ratio 1.36ab 1.34b 1.30b

ControlPerformance Parameter 0.05% Dry(Pre-pelleted)

0.10% Dry(Pre-pelleted)

Ration Plus Application Dose (Method)0.05% Liquid

(Post-pelleted)

Means with different letters in a row indicate significant difference (P≤0.10 by LSD test).

Page 2: Poultry Nutritional Supplement · Ration PlusTM supplemented through feed pelleted at 76.6°C (170°F) improved performance of Straight Run Cobb 500 broilers during 21 day evaluation

Cytozyme TechnologyOVERCOMING STRESS IMPACT

Ammonia buildup

Poor water quality

High humidity

High or low temperature

Crowding

Molds and toxins

Diseases, bacteria and viruses

Nutrient deficiency

ST

RE

SS

ST

RE

SS

Common ResponseReactive Oxygen Species (ROS)

OverproductionO2*

SuperoxideH2O2

HydrogenPeroxide

*OHHydroxylRadical

Cytozyme protects cells from overproduction of ROS

ROS overproduction damages cells and tissue

With Cytozyme

DNA damagemutations

Healthy membrane

Active proteins

Healthy DNA

Cells damaged by excessive production of ROS lose their integrity and can not support functions of the epithelial barrier leading to tissue destruction, mucosal inflammation, infections and lesions in the intestinal wall. Damage of the intestinal wall causes reduction of digestion efficiency and poor nutrient uptake.

Cytozyme products help to protect tissue from overproduction of ROS keeping cells healthy and supporting overall gut functions.

Protein breakdownand deactivation

Lesion score 2 Lesion score 0

Cytozyme products protect cells from overproduction of ROS reducing the impact of stress on animal production and increasing performance.

AntioxidantAnti-

oxidant

ROSROS

In a normal, healthy cell reactive oxygen species (ROS) are produced during processes involved in production of energy. ROS molecules act as important signaling molecules in a variety of cellular processes. In a healthy cell ROS are controlled and balanced by non-enzymatic antioxidant systems.

Stress causes an excessive production of reactive oxygen species (ROS) in the cell structures. These molecules cause oxidative (free radical) damage to phospholipids (components of cell membranes), proteins and DNA. All these oxidation processes lead ultimately to cell death.

Damaged membrane

Oxidation of phospholipids leads to damage of membranes causing destruction of mitochondria, lysosomes, endoplasmic reticulum and cell membrane resulting in disintegration of cell structure.

Healthy DNA ensures proper gene expression.

Oxidation of proteins leads to damage of their structure and deactivation of enzymatic activity resulting in disruption of metabolic processes.

CONCLUSION

With CytozymeWithout Cytozyme

Membranes ensure cell compartmentalization and proper cell functions.

Active proteins ensure optimal cell metabolism.

Mitochondria

Damaged DNA

DNA

Cell Membrane

Damaged Mitochondria

Damaged Cell Membrane

Damaged Rough Endoplasmic Reticulum

Damaged Smooth Endoplasmic Reticulum

Rough EndoplasmicReticulum

Smooth EndoplasmicReticulum

Golgi Apparatus

Lysosome

Damaged Lysosome

Peroxisome

Damaged Peroxisome

Damaged Golgi Apparatus

Cytozyme Laboratories, Inc.2700 South 600 WestSalt Lake City, Utah 84115, USAe-mail: [email protected]

Tel: (801) 533-9208Fax: (801) 537-1312www.cytozyme.com

Conclusion: Cytozyme products protect cells from overproduction of ROS reducing the impact of stress on animal production and increasing performance.

Overcoming the Impact of Stress