Poster Assignment Recap
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Transcript of Poster Assignment Recap
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Poster Assignment Recap• Step 1: choose a topic
• Step 2: choose a paper: – must have a hormone measure/manipulation– must have a behaviour measure/manipulation
• Step 3: read the paper very carefully! You should understand everything about this paper, and be able to explain simply
• Step 4: make your poster
• Step 5: practice your talk (5 minutes max!)
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Poster Judging• Each of you will judge 3 posters during the times
when they are not presenting• You will get the names of the three posters at
the conference• You will fill in a form to rank the posters you visit• You will also write up and turn in a summary of
each poster (one page per poster) that includes at least three questions you asked at the poster and the replies that you got
• Due date is the last class (Dec 6)
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ADX facilitates pairbonding
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CORT prevents pairbonding
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In males, pair-bonding can’t occur if adrenals removed
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In males, stress increases pair-bonding only if adrenals intact
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In males, CORT increases pair-bonding
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Vasopressin (VP1) receptor
Meadow vole Prairie Vole
Ventral pallidum – important for reinforcement, reward, addiction
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Transfection study
• Insert excess V1a gene into the ventral pallidum of prairie voles
VP staining: • reporter gene
(LacZ) only
• V1a
• Additional control was extra V1a in striatum (CP)
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Transfection Study
• VP V1a over-expression: • Increase in social behaviour overall• Pair-bonding even without mating • Agrees with antagonist studies
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Neurology of Aggression
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VMN AH
dorsal PAG
Defensive Aggression
+
+
+
LH-
-
Predation+
-
The two systems are mutually exclusive
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Predatory Aggression (Feeding)
Hypothalamus lateral hypothalamus (LH) stimulation elicits predatory attack
Medial amygdala stimulation inhibits predation via LH
Periaqueductal gray (PAG) stimulation also inhibits
predation
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Defensive Aggression
• Stimulation of the ventromedial nucleus of the hypothalamus (VMN) produces components of defensive aggression
• Lesions of anterior hypothalamus (AH) prevents VMN effects
• PAG stimulation also elicits defensive aggression
• Medial or basal amygdala stimulation facilitates attacks via VMH
• Central amygdala stimulation inhibits attacks via PAG
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Social Aggression
• These forms of aggression can be distinguised from social aggression
• Mostly done in mice and rats• Different neural substrates:
olfactory bulbs (chemosensory cues)basolateral amygdalamedial amygdala (but only if fighting experience)septummedial hypothalamusraphe nuclei (primary 5HT site)
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Androgens in Hyena Dominance• Adult females have high levels as well, but
still less than or similar to male
• Androgen levels are strongly correlated with status within sexes
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Challenge Effects
• Just like birds and mice
• Seems to require some sort of effort or “ego investment”
• Tennis vs Fan vs Lottery