Polymerase δ and ε in colon cancer
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Transcript of Polymerase δ and ε in colon cancer
Polymerase δ and εin colon cancer
Aaron Stevens
Polymerase δ and ε contain both polymerase and exonuclease domains
Polymerase δ and ε are the major replicative polymerases
Pol δ and ε help repair damage
Mutating the exonuclease domain leads to decreased survival rates
Point mutations in Pol δ are found in colon cancer
Mutating the exonuclease domain of Polymerase δ leads to cancer
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