Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which...

16
Poincaré Plots: A Mini-Review ReyLab, Beth Israel Deaconess Medical Center Harvard Medical School Dept. Psychiatry, Taipei Veterans General Hospital, Taiwan Albert C.-C. Yang, MD [email protected] HRV 2006

Transcript of Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which...

Page 1: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Poincaré Plots: A Mini­Review

ReyLab, Beth Israel Deaconess Medical CenterHarvard Medical School

Dept. Psychiatry, Taipei Veterans General Hospital, Taiwan

Albert C.­C. Yang, MD

[email protected]

HRV 2006

Page 2: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Henri Poincaré (1854­1912)

Page 3: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Poincaré plot Poincaré HRV plot is a graph in which each 

RR interval is plotted against next RR interval (a type of delay map)

Synonyms Scatter plot; scattergram Return map; phase delay map Lorenz plot

Page 4: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Poincaré & related plots as nonlinear toolsVisualization of higher­dimensional phase spaces 

in two or three­dimensional sub­spaces 

Source: http://en.wikipedia.org/wiki/Recurrence_plot

uncorrelated noise harmonic oscillationchaotic time series with linear trend 

time series generated from an AR model 

Page 5: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Poincaré HRV plot: normal

RRn (ms)

RRn+

1 (m

s)

Page 6: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Visualization of ectopic beats

normal beats

normal     ectopicectopic  post­ectopicpost­ectopic    normal 

Page 7: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Critically ill PatientHealthy Controlmean heart rate : 52 bpm mean heart rate : 51 bpm

Poincaré HRV plot: healthy vs. disease

Data Source: Taipei Veterans General Hospital, Taiwan

Page 8: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

   Early­detected    cancer patient

          Hospice      cancer patient

   Chemotherapy     cancer patient

HRV in different stages of cancer

Data Source: Taipei Veterans General Hospital, Taiwan

Page 9: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

How aging and illness may affect the geometry of Poincaré HRV plot

Prematurely (22th week)Newborn (one day)

10­year­old healthy control

25­year­old healthy control

Critically ill patient in ICU

Data Source: Taipei Veterans General Hospital, Taiwan

RRn (ms)

RRn+

1 (m

s)

Page 10: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Quantitative analysis of Poincaré HRV plots

Ellipse fitting technique Histogram technique Correlation coefficient

Variable geometries of Poincaré HRV plots

Page 11: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Ellipse fitting technique

Huikuri, H. V. et al. Circulation 1996;93:1836­1844

SD2

SD1

SD1: dispersion (standard  deviation) of points perpendicular to the axis of line­of­identity

SD2: dispersion (standard deviation) of points along the axis of line­of­identity

Line­of­identity

Page 12: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Ellipse fitting technique – Risk Stratification in Cardiovascular Disease

Stein PK et al. Indian Pacing and Electrophysiology Journal 2005;5:210­220

Page 13: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Histogram technique

Brennan M. et al. IEEE Trans Biomed Eng 2001;48:1342­47

Page 14: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Do these indices actually measure nonlinear properties of heart rate dynamics

Tulppo MP et al. Am J Physiol 1996;271:H244­H252

Page 15: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Ellipse fitting technique

Do these indices actually measure nonlinear properties of heart rate dynamics

Brennan M. et al. IEEE Trans Biomed Eng 2001;48:1342­47

SDRR : standard deviation of the RR intervals

SDSD: standard deviation of the successive differences of the RR intervals

Page 16: Poincaré Plots: A MiniReview - PhysioNet · Poincaré plot Poincaré HRV plot is a graph in which each RR interval is plotted against next RR interval (a type of delay map)

Summary Advantages

Simple visualization tool  Outlier (ectopic beat or artifact) identifier Possible insights into short­term and long­term 

variability  Limitations

Derived statistics not independent of other time domain measures