Plasma Membrane Fix 2
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Transcript of Plasma Membrane Fix 2
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Plasma
MembraneCreated by :
Dyah Candra PalupiSyarifatul LailiAnggun ArifkaDiah Ajeng S.
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Function Of Plasma
Membrane• Plasma membrane is a limit betweencell and its environment.
• Plasma membrane has receptor thatbond with extracellular matrix element
• Plasma membrane also containhormone receptor
• The cell surface also containenzymatic activity
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peci!c Function Of PlasmaMembrane
". The Function Of Cell #oundary Protect the food substances in cell ome of the elements bac$!lled throu%h metabolism
ener%y
The useful substrate been collected or synthesizedby cell As place to excrete the metabolism waste
&. 'nsulatin% Function
Cells react to chan%es (evelop the receptor to reco%nize cell )ormone start to wor$ on certain receptor in plasma
membrane
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Plasma Membrane tructure(ia%ram
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urface Membrane
• The outer surface of both layer is ,surface that faced cell and facedhydrophobic
• The inner surface of both layer has Psurface that faced protoplasm andhydrophobic
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Composition PlasmaMembrane
• Plasma Membrane consist of lipidsand proteins
• There are - $inds of lipids membrane Phospholipids/ Cholesterol and0lycoprotein
• Plasma Membrane structure andchemical composition are varies
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Phospholipids/ Cholesteroland 0lycoprotein
• Phospholipids are amphipathicmolecules/ thus directly formin% alayer of micelles in a li1uid
environment.
• Cholesterol in a form of amphiphaticand located between phospholipids on
membrane.• 0lycolipids is amphiphatic membrane
element.
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Types of MembraneProteins
". Cell2cell reco%nition proteins
&. 'nte%rins
-. 'ntercellular 3unction proteins
4. ,nzymes
5. i%nal transduction proteins A$a 2 6eceptor proteins
7. Transport proteins Passive and active
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• Cell2cell reco%nition proteins 2
identify type of cell and identify a cellas 8self9 versus forei%n
– Most are %lycoproteins
• Carbohydrate chains vary between species/individuals/ and even between cell types in a%iven individual.
• 0lycolipids also play a role in cell reco%nition
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• 'nte%rins are a type of inte%ralprotein
– The cytos$eleton attaches to inte%rins
on the cytoplasmic side of themembrane
– 'nte%rins stren%then the membrane
• 'ntercellular 3unction proteins 2 helpli$e cells stic$ to%ether to formtissues
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• i%nal transduction :receptor;proteins bind hormones and othersubstances on the outside of the cell.
– #indin% tri%%ers a chan%e inside the cell.
• Called signal transduction
• ,xample The bindin% of insulin to insulin
receptors causes the cell to put %lucosetransport proteins into the membrane.
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Messenger molecule
Activatedmolecule
Receptor
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Transport of ubstances Acrossthe Plasma Membrane :PM;
". Passive Transport
› imple (i
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Passive Transport
• In passive transport substancescross the membrane by difusion
– (i
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Factors A
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imple (i
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Facilitated (i
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Facilitated (i
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Osmosis
• Osmosis @ diout of the cellthrou%h a1uaporins 2 protein y%berupa pori9 u membantu 3alannyaair melewati membran
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Osmosis Terms
Consider two solutions separated by a plasma membrane.
Hypertonic› solution with a relatively hi%h concentration of
solute
Hypotonic› solution with a relatively low concentration of
solute
Isotonic› solutions with the same solute concentration
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Osmosis and Animal Cells
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Osmosis and Plant Cells
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Active Transport
• Active transport proteins movesubstances across the PM a%ainsttheir concentration %radient.
– 6e1uires ener%y :ATP;
– Active transport proteins are hi%hlyselective
– Active transport is needed for properfunctionin% of nerves and muscles
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Active Transport
ATP
ATP
P
ADP
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Vesicle
Fluid outside cell
Protein
ytoplasm
ExocytosisExocytosis
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E d t iE d t i
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Vesicle #orming
EndocytosisEndocytosis
,ndocytosis can occur in three ways,ndocytosis can occur in three ways
Pha%ocytosis :Dcell eatin%D;Pha%ocytosis :Dcell eatin%D;
Pinocytosis :Dcell drin$in%D;Pinocytosis :Dcell drin$in%D;
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,ndocytosis
• ,ndocytosis
– PM sin$s inward/ pinches o< and forms avesicle
– Besicle often mer%es with 0ol%i forprocessin% and sortin% of its contents
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,ndocytosis 2 terms
• Pha%ocytosis @ cell eatin%
– Membrane sin$s in and captures solidparticles for transport into the cell
– ,xamples
• olid particles often include bacteria/cell debris/ or food
• Pinocytosis @ cell drin$in% – Cell brin%s in a li1uid
http://academic.brooklyn.cuny.edu/biology/bio4fv/page/phago.htmhttp://academic.brooklyn.cuny.edu/biology/bio4fv/page/phago.htm
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T)A=G FO6
HOI6
ATTA=T'O=
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". Protein apa yan% masu$ pada prosesendositosis J Kida rL
&. Pada slide $e & pada proses e$sositosis
apa$ah ada fa$tor protein tertentu yan%mendoron% pen%eluaran tersebut J :nira;
-. Apa fun%si reseptor ion/ reseptor tirosin $inasedan protein 0 J :ridlo;
4. Apa$ah fun%si membran plasma selalu tetap /
$alau bisa rusa$/ $enapa J :nayla;5. Apa$ah stru$tur membran sama $eti$a
mela$u$an endositosis dan e$sositosis sepertidi$etahui terdapat sitos$eleton J :adini;
7. Fa$tor apa yan% menyebab$an salahpenerimaan sinyal di reseptor J :nina;
N. i$a plasma membran sudah rusa$ apa$ah adasistem pertahanan di dalam sel J :noya;