Pine.Bio slide deck - Idea Village CAPITALx (New Orleans Entrepreneur Week 2017)
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Transcript of Pine.Bio slide deck - Idea Village CAPITALx (New Orleans Entrepreneur Week 2017)
PINEBIOAnalytics for molecular data in healthcare
CLINICAL DATA
GENOMICS
TRANSCRIPTOMICS
MICROBIOME
PROTEOMICS
EPIGENETICS
disease symptoms
CANCERwill this affect my family?how long do I have?what exactly is going on?what is the best treatment?
1,600,000People die from cancer every
year in the US alone…
24%relapse or exhaust standard of care
radiologist
medical oncologist
surgical oncologist
patient
pathologist
drug interactions
clinical trials
co-morbidities
epigenetic biomarkers
circulating tumor cells
copy number variation
new screens
combination therapies
resistance development
cfDNA markers
micro biome variation
PERSONALIZED CARE
PRECISION INSIGHT
data aggregation better decisions
PINEBIO
research and discovery molecular diagnostics
ANALYTICAL DASHBOARDS
PERSONALIZED CLINICAL INTERFACE
POWERFUL DATA ANALYSIS ENVIRONMENT
PROTEIN-DRUG INTERACTIONS
STRUCTURALSCREENING
MUTATION ANALYSIS
12
3
ACADEMIC HOSPITALS PHARMA COMPANIES
BUSINESS MODEL
SAAS LICENSE SERVICES DATA+ +
RESEARCH TEAMS
less headaches for doctors
more options for
patients
DR. ALFRED TAUBER DR. LEONID BRODSKYEstablished one of the first bioinformatics labs at Lomonosov Moscow State University in 1989. Dr. Leonid Brodsky has been leading bioinformatics research, computational biology and systems biology modeling for over 30 years. His expertise and methods contributed to numerous scientific discoveries and publications. Currently, he is a Senior Reseach associate, and the Director of the Tauber Bioinformatics Research Center in University of Haifa
Zoltan Kohn Professor Emeritus of Medicine at Boston University. Originally trained as a biochemist and hematologist. Aside from over 125 research publications in
biochemistry and cell biology, Tauber has published extensively on 19th and 20th century biomedicine, the development of modern immunology, the doctor-patient
relationship, and contemporary science studies. In 2013 Tauber was appointed Chairman of the Board of Governors of the University of Haifa.
COMPANY FOUNDERS
CORE TEAM
ELIA BRODSKY AVI TITIEVSKY PRIYAL DE ZOYSAJACLYN WILLIAMS
Harvard Business School HBX CORe, Bar Ilan Applied
Mathematics, BA in Visual Communications and
Marketing. A number of previous startups as founder
or co-founder.
MS in Computer Science and Ph.D. candidate in Machine
Learning for Systems Engineering. Has been
working closely with TBRC for the past 6 years at Haifa
University.
MS in Microbiology from University of South
Mississippi. Experience in lab management, genomics and bioinformatics and several
publications in microbiology.
Background in big Pharma and tech companies such as
Seven Bridges, Life technologies. Ph.D. in
BioScience and Biotechnology.
TRACTION & MILESTONES:
in October 2016, our multi-omics platform was awarded
the grand prize of $20,000 in a startup competition organized
by the Pistoia Alliance, a professional organization that brings together big Pharma
and tech companies
Starting in March 2017, our team is collaborating on a DARPA-
funded projects with researchers from University of San Francisco, Boston University, CDC, IBM and others. This a multi-million dollar project seeks to develop a new
therapeutic for infectious diseases.
For the past several months, our team has participated in a number of business accelerator programs, including the Propeller Health Accelerator and the CAPITALx program run by the Idea
Village. These programs and the team at the New Orleans BioInnovation Center are helping prepare our company for growth.
VALIDATION PROJECTS AND EARLY ADOPTERS:
LOW FREQUENCY MUTATION DETECTION IN VIROLOGY: COLLABORATION WITH UCSF, STANFORD AND OTHERS TO DEVELOP A METHOD OF HOST-PATHOGEN INTERACTIONS USING ULTRA DEEP SEQUENCING.
DARPA INTERCEPT PROGRAM:WORKING WITH RESEARCH AND MODELING TEAMS FROM UCSF, BU, STANFORD AND IBM AS A DATA ANALYTICS AND MANAGEMENT PLATFORM PROVIDER. THE OBJECTIVE OF THE PROJECT IS DEVELOPMENT OF NEW THERAPEUTICS
CLINICAL TRIALS DATA:WORKING ON A CLINICAL TRIAL DATASET FOR ACCORD THERAPEUTICS TO IDENTIFY BIOMARKERS FOR DRUG RESPONSE
CLINICAL CANCER STUDIES:A NUMBER OF VALIDATION PROJECTS WITH RESEARCHERS AT LSU HEALTH SCIENCES AND TULANE MEDICAL SCHOOL TO DEVELOP EFFECTIVE WORKFLOWS AROUND EARLY DETECTION OF PATIENTS WHERE MOLECULAR INSIGHT CAN LEAD TO MORE EFFECTIVE TREATMENTS
BASIC RESEARCH PROJECTS:COLLABORATION WITH A NUMBER OF RESEARCHERS ON TARGET DISCOVERY AND ANALYSIS OF MULTI-OMICS DATASETS FOR PLATFORM DEVELOPMENT AND REFINEMENT
OCT. 2015 DEC. 2015 JULY. 2016 MARCH. 2017 APRIL. 2017