Physiology & The Menstrual Cycle - wesley ob/gyn · 2016-07-05 · Physiology & The Menstrual Cycle...
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Physiology & The Menstrual Cycle David A. Grainger, MD, MPH July 8, 2015
Transcript of Physiology & The Menstrual Cycle - wesley ob/gyn · 2016-07-05 · Physiology & The Menstrual Cycle...
Physiology & The Menstrual Cycle
David A. Grainger, MD, MPH
July 8, 2015
Disclosures
• I have no disclosures.
Learning Objective
• To understand the menstrual cycle
12 51
20 weeksBirth
menopausemenarche
6-7 million
1-2 million500,000
0
Medial Basal Hypothalamus
Pituitary
Ovary
Medial Basal Hypothalamus
Pituitary
Ovary
TSHPRLACTHGHFSHLH
OxytocinVasopressin
Median eminence
Arcuate nucleus
GnRH
XXXXX XXXXX
E2 LH
FSH
Follicular Phase LH Surge Luteal PhaseProliferative Phase Secretory Phase
LH
FSH
Theca
Granulosa
Oocyte
Cumulus
Medial Basal Hypothalamus
Pituitary
Ovary
TSHPRLACTHGHFSHLH
OxytocinVasopressin
Median eminence
Arcuate nucleus
Sex steroids (progesterone, androgens, estrogens)Inhibin
GnRH
LH Surge:
1. Induces Ovulation1. PG production2. Proteolytic Enzyme
induction2. Shift from Estrogen to
Progesterone production3. Resumption of Meiosis
XXXXX XXXXX
E2
P4
LH
FSH
Follicular Phase LH Surge Luteal PhaseProliferative Phase Secretory Phase
40 hoursovulation
