Physioex 2 Act 1and2
Transcript of Physioex 2 Act 1and2
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Introduction
• Skeletal muscles are connected to the skeletonto form part of the mechanical system thatmoves the limbs and other parts of the body.
• Physiological skeletal muscle contractionrequires generation and spread of a membraneaction potential, transduction of the electrical
energy into an intracellular chemical signalthat, in turn, triggers myolament interaction.
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Introduction
• Force Transducers are also commonlykno!n as Force Sensors . It is dened asa transducer that converts an input
mechanical force into an electrical outputsignal.
• In this e"periment an isolated skeletalmuscle is isolated and !as mounted on a
force transducer to generate musclecontractions !ith controlled electricalstimulations.
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%b&ective' To Identify and measure duration of the latent
period
To understand' (lectrical stimulus
e"citation)contraction coupling
*uscle t!itch
+atent period
ontraction phase
-ela"ation phase
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Skeletal muscle
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+atent period did not change !hendi/erent voltages of stimulus !ereapplied
) in bet!een muscle stimulation andbeginning of muscle response
-ole of acetylcholine
-elease at end)plate potential
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• %b&ective'
– Identify treshold stimulus
– 1nderstand'
2o! motor unit recuitment can increase the tension a!hole muscle develops
2o! Increasing stimulus voltage to an isolatedmuscle in an e"periment
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• Stimulus voltage directly proportionalon the amount of active force – *ore bers and motor neurons are
activated
• #t ma"imal voltage, all muscle bershad generated there ma"imal force
thus they are all depolari3ed and aresuccessfully recruited.